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FBXO2 ,FBXO2 ,Q9UK22
  • Number of Interaction partner in intact: 20
  • Number of Interaction partner in biogrid: 350
  • Number of Interaction partner in hippie: 396
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 Not Cancer Driver No 1 hippie, biogrid 240 497 44 44 0
ACP2 ACP2 P11117 Lysosomal acid phosphatase chr11 Not Cancer Driver No 1 hippie, biogrid 41 77 11 11 0
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 Not Cancer Driver No 1 hippie, biogrid 88 156 20 20 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 Not Cancer Driver No 1 hippie, biogrid 80 182 17 17 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 Not Cancer Driver No 1 hippie, biogrid 175 162 26 26 0
ADAM33 ADAM33 Q9BZ11 Disintegrin and metalloproteinase domain-containing protein 33 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 94 165 28 28 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 Not Cancer Driver No 1 hippie, biogrid 86 129 13 13 0
ADAMTS7 ADAMTS7 Q9UKP4 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 Not Cancer Driver No 1 hippie, biogrid 244 640 100 100 0
ADGRA3 ADGRA3 Q8IWK6 Adhesion G protein-coupled receptor A3 chr4 Not Cancer Driver No 1 hippie 197 347 52 52 0
ADGRF1 ADGRF1 Q5T601 Adhesion G-protein coupled receptor F1 chr6 Not Cancer Driver No 1 hippie 159 8 0 0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 Not Cancer Driver No 1 hippie 64 67 4 4 9
ADGRG6_ENST00000230173 ADGRG6 Q86SQ4 Adhesion G-protein coupled receptor G6 chr6 Not Cancer Driver No 1 hippie 132 23 0 0 2
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 Not Cancer Driver No 1 hippie 1124 496 77 77 2
AGA AGA P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase chr4 Not Cancer Driver No 1 hippie, biogrid 46 78 11 11 12
AGRN AGRN O00468 Agrin chr1 Not Cancer Driver No 1 hippie, biogrid 188 490 40 40 5
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 1 hippie 74 131 41 41 0
ALCAM ALCAM Q13740 CD166 antigen chr3 Not Cancer Driver No 2 intact, hippie, biogrid 89 96 19 19 0
AMIGO3 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 Not Cancer Driver No 2 hippie, biogrid 69 60 7 7 0
AMOT AMOT Q4VCS5 Angiomotin chrX Not Cancer Driver No 1 hippie, biogrid 161 909 128 128 0
AMOTL1 AMOTL1 Q8IY63 Angiomotin-like protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 136 851 121 121 0
AMOTL2_ENST00000422605 AMOTL2 Q9Y2J4 Angiomotin-like protein 2 chr3 Not Cancer Driver No 1 hippie, biogrid 94 741 93 93 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie 104 146 26 26 0
ANKRD46_ENST00000519597 ANKRD46 Q86W74 Ankyrin repeat domain-containing protein 46 chr8 Not Cancer Driver No 1 hippie, biogrid 28 30 1 1 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 Not Cancer Driver No 1 hippie, biogrid 134 80 11 11 0
ARSB ARSB P15848 Arylsulfatase B chr5 Not Cancer Driver No 1 hippie, biogrid 59 81 6 6 29
ARSK ARSK Q6UWY0 Arylsulfatase K chr5 Not Cancer Driver No 1 hippie, biogrid 70 9 2 2 0
ASIC4_ENST00000358078 ASIC4 A0A8I5KPF5 Acid-sensing ion channel 4 chr2 Not Cancer Driver No 2 hippie, biogrid 121 249 35 35 0
ASIC5 ASIC5 Q9NY37 Acid-sensing ion channel 5 chr4 Not Cancer Driver No 1 hippie, biogrid 112 12 4 4 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 Not Cancer Driver No 1 hippie, biogrid 88 468 59 59 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 Not Cancer Driver No 1 hippie, biogrid 70 557 59 59 0
ATRN ATRN O75882 Attractin chr20 Not Cancer Driver No 1 hippie, biogrid 136 53 5 5 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 Not Cancer Driver No 1 hippie, biogrid 168 341 64 64 0
AZU1 AZU1 P20160 Azurocidin chr19 Not Cancer Driver No 3 intact, hippie, biogrid 42 53 13 13 0
B3GALNT2 B3GALNT2 Q8NCR0 UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 chr1 Not Cancer Driver No 1 hippie, biogrid 39 0 0 0 4
B3GNT2 B3GNT2 Q9NY97 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 51 22 6 6 0
B3GNT3_ENST00000595387 B3GNT3 Q9Y2A9 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 chr19 Not Cancer Driver No 1 hippie, biogrid 69 44 6 6 0
B4GALT3_ENST00000367998 B4GALT3 O60512 Beta-1,4-galactosyltransferase 3 chr1 Not Cancer Driver No 1 hippie, biogrid 56 171 27 27 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 Not Cancer Driver No 1 hippie 55 53 5 5 0
BCHE BCHE P06276 Cholinesterase chr3 Not Cancer Driver No 2 intact, hippie, biogrid 185 14 4 4 38
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 119 154 25 25 3
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 Not Cancer Driver No 1 hippie, biogrid 86 142 26 26 5
BOC_ENST00000355385 BOC Q9BWV1 Brother of CDO chr3 Not Cancer Driver No 2 intact, hippie, biogrid 175 568 92 92 0
BRAP BRAP Q7Z569 BRCA1-associated protein chr12 Not Cancer Driver No 1 hippie 70 192 24 24 0
BTD_ENST00000643237 BTD P43251 Biotinidase chr3 Not Cancer Driver No 1 hippie, biogrid 63 13 1 1 9
BTN2A1 BTN2A1 Q7KYR7 Butyrophilin subfamily 2 member A1 chr6 Not Cancer Driver No 1 hippie, biogrid 86 38 9 9 0
C1RL C1RL Q9NZP8 Complement C1r subcomponent-like protein chr12 Not Cancer Driver No 1 hippie, biogrid 60 146 22 22 0
C4BPB C4BPB P20851 C4b-binding protein beta chain chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
C8A C8A P07357 Complement component C8 alpha chain chr1 Not Cancer Driver No 1 hippie, biogrid 176 25 9 9 0
CACHD1 CACHD1 Q5VU97 VWFA and cache domain-containing protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 174 206 25 25 0
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 Not Cancer Driver No 1 hippie, biogrid 277 99 25 25 0
CACNA2D2 CACNA2D2 Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2 chr3 Not Cancer Driver No 1 hippie, biogrid 126 185 20 20 1
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 Not Cancer Driver No 1 hippie, biogrid 48 94 9 9 0
CAV2 CAV2 P51636 Caveolin-2 chr7 Not Cancer Driver No 1 intact, hippie 20 5 2 2 0
CBLIF CBLIF P27352 Cobalamin binding intrinsic factor chr11 Not Cancer Driver No 1 intact, hippie 67 61 11 11 1
CBLN4 CBLN4 Q9NTU7 Cerebellin-4 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 62 20 10 10 0
CCDC28A CCDC28A Q8IWP9 Coiled-coil domain-containing protein 28A chr6 Not Cancer Driver No 1 hippie, biogrid 50 198 28 28 0
CD101 CD101 Q93033 Immunoglobulin superfamily member 2 chr1 Not Cancer Driver No 1 hippie, biogrid 135 137 18 18 0
CD109 CD109 Q6YHK3 CD109 antigen chr6 Not Cancer Driver No 1 hippie, biogrid 204 54 11 11 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 Not Cancer Driver No 1 hippie, biogrid 42 60 5 5 0
CD276 CD276 Q5ZPR3 CD276 antigen chr15 Not Cancer Driver No 1 hippie, biogrid 62 139 10 10 0
CD320 CD320 Q9NPF0 CD320 antigen chr19 Not Cancer Driver No 1 hippie, biogrid 30 82 9 9 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 Not Cancer Driver No 1 hippie, biogrid 37 0 0 0 0
CD48_ENST00000368046 CD48 P09326 CD48 antigen chr1 Not Cancer Driver No 1 hippie, biogrid 39 2 0 0 0
CDHR2 CDHR2 Q9BYE9 Cadherin-related family member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 237 251 52 52 0
CDHR4 CDHR4 A6H8M9 Cadherin-related family member 4 chr3 Not Cancer Driver No 1 hippie, biogrid 54 111 4 4 0
CELSR3 CELSR3 Q9NYQ7 Cadherin EGF LAG seven-pass G-type receptor 3 chr3 Not Cancer Driver No 1 hippie, biogrid 395 1315 167 167 0
CEMIP2 CEMIP2 Q9UHN6 Cell surface hyaluronidase chr9 Not Cancer Driver No 1 hippie 198 229 26 26 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 Not Cancer Driver No 1 hippie, biogrid 207 105 10 10 0
CHST10_ENST00000409701 CHST10 O43529 Carbohydrate sulfotransferase 10 chr2 Not Cancer Driver No 1 hippie, biogrid 59 15 1 1 0
CHST12 CHST12 Q9NRB3 Carbohydrate sulfotransferase 12 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 75 84 15 15 0
CHST8_ENST00000434302 CHST8 Q9H2A9 Carbohydrate sulfotransferase 8 chr19 Not Cancer Driver No 1 hippie, biogrid 105 150 23 23 1
CILP2 CILP2 Q8IUL8 Cartilage intermediate layer protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 207 401 86 86 0
CLN5_ENST00000377453 CLN5 O75503 Ceroid-lipofuscinosis neuronal protein 5 chr13 Not Cancer Driver No 1 hippie, biogrid 39 16 1 1 12
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 83 163 19 19 0
CNTN1 CNTN1 Q12860 Contactin-1 chr12 Not Cancer Driver No 1 hippie, biogrid 265 220 50 50 0
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 173 141 15 15 6
CNTNAP3 CNTNAP3 Q9BZ76 Contactin-associated protein-like 3 chr9 Not Cancer Driver No 1 hippie, biogrid 181 216 14 14 0
CNTNAP3B CNTNAP3B Q96NU0 Contactin-associated protein-like 3B chr9 Not Cancer Driver No 1 hippie, biogrid 125 217 16 16 0
COCH_ENST00000643575 COCH O43405 Cochlin chr14 Not Cancer Driver No 1 hippie, biogrid 81 43 6 6 14
COL12A1 COL12A1 Q99715 Collagen alpha-1(XII) chain chr6 Not Cancer Driver No 1 hippie, biogrid 553 1413 266 266 2
COL14A1 COL14A1 Q05707 Collagen alpha-1(XIV) chain chr8 Not Cancer Driver No 1 hippie, biogrid 402 711 188 188 0
COL18A1 COL18A1 P39060 Collagen alpha-1(XVIII) chain chr21 Not Cancer Driver No 1 hippie, biogrid 179 1284 142 142 0
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 Not Cancer Driver No 1 hippie, biogrid 145 434 61 61 12
COL6A2 COL6A2 P12110 Collagen alpha-2(VI) chain chr21 Not Cancer Driver No 1 hippie, biogrid 220 460 97 97 10
COLEC12 COLEC12 Q5KU26 Collectin-12 chr18 Not Cancer Driver No 1 hippie, biogrid 147 450 90 90 0
CPD CPD O75976 Carboxypeptidase D chr17 Not Cancer Driver No 1 hippie, biogrid 131 476 45 45 0
CREG1 CREG1 O75629 Protein CREG1 chr1 Not Cancer Driver No 1 hippie, biogrid 12 31 0 0 0
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 51 101 7 7 14
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 Not Cancer Driver No 1 hippie, biogrid 259 838 85 85 0
CSTL1_ENST00000246020 CSTL1 Q9H114 Cystatin-like 1 chr20 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CTBS CTBS Q01459 Di-N-acetylchitobiase chr1 Not Cancer Driver No 1 hippie, biogrid 40 0 0 0 0
CTF1 CTF1 Q16619 Cardiotrophin-1 chr16 Not Cancer Driver No 1 hippie, biogrid 6 90 4 4 0
CTHRC1 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 Not Cancer Driver No 1 hippie, biogrid 31 62 5 5 0
CTSF CTSF Q9UBX1 Cathepsin F chr11 Not Cancer Driver No 1 hippie, biogrid 63 78 7 7 4
CTSV CTSV O60911 Cathepsin L2 chr9 Not Cancer Driver No 1 hippie, biogrid 55 7 1 1 0
CTSZ CTSZ Q9UBR2 Cathepsin Z chr20 Not Cancer Driver No 1 hippie, biogrid 30 10 0 0 0
CTU1 CTU1 Q7Z7A3 Cytoplasmic tRNA 2-thiolation protein 1 chr19 Not Cancer Driver No 1 hippie, biogrid 12 60 1 1 0
CUL1_ENST00000602748 CUL1 Q13616 Cullin-1 chr7 Not Cancer Driver No 1 hippie 151 65 9 9 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 Not Cancer Driver No 1 hippie 188 372 41 41 3
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 Not Cancer Driver No 1 hippie, biogrid 102 485 61 61 4
DNAJC13 DNAJC13 O75165 DnaJ homolog subfamily C member 13 chr3 Not Cancer Driver No 1 hippie, biogrid 276 141 17 17 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 Not Cancer Driver No 1 hippie, biogrid 192 257 61 61 5
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 Not Cancer Driver No 1 hippie, biogrid 193 158 17 17 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 Not Cancer Driver No 1 hippie, biogrid 118 99 26 26 1
ECPAS_ENST00000338205 ECPAS Q5VYK3 Proteasome adapter and scaffold protein ECM29 chr9 Not Cancer Driver No 1 hippie 176 240 22 22 0
EDEM2 EDEM2 Q9BV94 ER degradation-enhancing alpha-mannosidase-like protein 2 chr20 Not Cancer Driver No 1 hippie, biogrid 69 54 3 3 0
EDIL3 EDIL3 O43854 EGF-like repeat and discoidin I-like domain-containing protein 3 chr5 Not Cancer Driver No 1 hippie, biogrid 135 44 16 16 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 444 223 35 35 1
EMB EMB Q6PCB8 Embigin chr5 Not Cancer Driver No 1 hippie, biogrid 78 96 18 18 0
EMC1 EMC1 Q8N766 ER membrane protein complex subunit 1 chr1 Not Cancer Driver No 1 hippie, biogrid 107 59 6 6 2
EMC3 EMC3 Q9P0I2 ER membrane protein complex subunit 3 chr3 Not Cancer Driver No 1 hippie, biogrid 26 31 6 6 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 Not Cancer Driver No 1 hippie, biogrid 15 17 2 2 0
EMC7 EMC7 Q9NPA0 ER membrane protein complex subunit 7 chr15 Not Cancer Driver No 1 hippie, biogrid 35 54 10 10 0
EMC8 EMC8 O43402 ER membrane protein complex subunit 8 chr16 Not Cancer Driver No 1 hippie, biogrid 15 20 0 0 0
EMILIN2 EMILIN2 Q9BXX0 EMILIN-2 chr18 Not Cancer Driver No 1 hippie, biogrid 158 617 94 94 0
EMILIN3 EMILIN3 Q9NT22 EMILIN-3 chr20 Not Cancer Driver No 1 hippie, biogrid 97 337 40 40 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 Not Cancer Driver No 1 hippie, biogrid 148 101 5 5 33
ENPP4 ENPP4 Q9Y6X5 Bis(5'-adenosyl)-triphosphatase ENPP4 chr6 Not Cancer Driver No 1 hippie, biogrid 79 20 4 4 0
ENPP5 ENPP5 Q9UJA9 Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 chr6 Not Cancer Driver No 1 hippie, biogrid 88 8 1 1 0
EPDR1 EPDR1 Q9UM22 Mammalian ependymin-related protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 40 38 11 11 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 Not Cancer Driver No 1 hippie, biogrid 147 211 38 38 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 Not Cancer Driver No 1 hippie, biogrid 341 83 39 39 0
EPHB4 EPHB4 P54760 Ephrin type-B receptor 4 chr7 Not Cancer Driver No 1 hippie, biogrid 125 184 19 19 11
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 Not Cancer Driver No 1 hippie, biogrid 97 23 4 4 0
ERO1B ERO1B Q86YB8 ERO1-like protein beta chr1 Not Cancer Driver No 2 intact, hippie 59 20 2 2 0
ERVMER34-1 ERVMER34-1 Q9H9K5 Endogenous retroviral envelope protein HEMO chr4 Not Cancer Driver No 1 hippie, biogrid 20 30 1 1 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 Not Cancer Driver No 1 hippie, biogrid 466 110 16 16 360
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 Compendium Yes 1 hippie, biogrid 607 135 24 24 30
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 Census, Compendium Yes 1 hippie, biogrid 152 230 43 43 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 Census, Compendium Yes 1 hippie, biogrid 238 228 44 44 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 hippie, biogrid 173 241 26 26 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 Census, Compendium Yes 1 hippie, biogrid 113 162 28 28 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 Not Cancer Driver No 1 hippie, biogrid 299 103 20 20 0
FN1 FN1 P02751 Fibronectin chr2 Compendium Yes 1 hippie, biogrid 394 1243 185 185 8
FOLR3 FOLR3 P41439 Folate receptor gamma chr11 Not Cancer Driver No 1 hippie, biogrid 58 15 4 4 0
FRAS1 FRAS1 Q86XX4 Extracellular matrix organizing protein FRAS1 chr4 Not Cancer Driver No 1 hippie, biogrid 628 806 116 116 0
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 Not Cancer Driver No 1 hippie, biogrid 101 147 18 18 131
GALNT5 GALNT5 Q7Z7M9 Polypeptide N-acetylgalactosaminyltransferase 5 chr2 Not Cancer Driver No 1 hippie, biogrid 147 399 56 56 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 Not Cancer Driver No 1 hippie, biogrid 82 42 6 6 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 Not Cancer Driver No 2 intact, hippie, biogrid 72 53 15 15 0
GGCX GGCX P38435 Vitamin K-dependent gamma-carboxylase chr2 Not Cancer Driver No 1 hippie, biogrid 77 131 15 15 8
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 Not Cancer Driver No 1 hippie 34 0 0 0 46
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 134 103 7 7 0
GNPTAB GNPTAB Q3T906 N-acetylglucosamine-1-phosphotransferase subunits alpha/beta chr12 Not Cancer Driver No 1 hippie, biogrid 144 259 23 23 25
GNS GNS P15586 N-acetylglucosamine-6-sulfatase chr12 Not Cancer Driver No 1 hippie, biogrid 48 22 0 0 3
GPAA1 GPAA1 O43292 Glycosylphosphatidylinositol anchor attachment 1 protein chr8 Not Cancer Driver No 1 hippie, biogrid 55 20 3 3 5
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 Not Cancer Driver No 1 hippie, biogrid 88 190 15 15 13
GRN GRN P28799 Progranulin chr17 Not Cancer Driver No 1 hippie, biogrid 76 29 6 6 1
GUSB GUSB P08236 Beta-glucuronidase chr7 Not Cancer Driver No 1 hippie, biogrid 93 11 0 0 36
GXYLT1 GXYLT1 Q4G148 Glucoside xylosyltransferase 1 chr12 Not Cancer Driver No 1 hippie, biogrid 58 7 0 0 0
GZMH GZMH P20718 Granzyme H chr14 Not Cancer Driver No 1 hippie, biogrid 47 50 14 14 0
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 Not Cancer Driver No 1 hippie, biogrid 96 39 3 3 2
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 Not Cancer Driver No 1 hippie, biogrid 45 0 0 0 9
HK2 HK2 P52789 Hexokinase-2 chr2 Not Cancer Driver No 1 hippie, biogrid 138 77 7 7 0
HPSE HPSE Q9Y251 Heparanase chr4 Not Cancer Driver No 1 hippie, biogrid 90 16 2 2 0
HS6ST1 HS6ST1 O60243 Heparan-sulfate 6-O-sulfotransferase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 60 66 14 14 6
HS6ST2_ENST00000406696 HS6ST2 Q96MM7 Heparan-sulfate 6-O-sulfotransferase 2 chrX Not Cancer Driver No 1 hippie, biogrid 77 184 20 20 0
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 Compendium Yes 1 hippie, biogrid 506 1709 194 194 1
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 Not Cancer Driver No 1 hippie, biogrid 132 373 47 47 0
ICAM5 ICAM5 Q9UMF0 Intercellular adhesion molecule 5 chr19 Not Cancer Driver No 1 hippie, biogrid 103 419 47 47 0
IDUA IDUA P35475 Alpha-L-iduronidase chr4 Not Cancer Driver No 1 hippie, biogrid 46 101 5 5 57
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 Compendium Yes 1 hippie, biogrid 55 175 22 22 10
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 Not Cancer Driver No 1 hippie, biogrid 183 265 37 37 6
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 Not Cancer Driver No 1 hippie, biogrid 318 255 20 20 0
IGSF3_ENST00000369486 IGSF3 O75054 Immunoglobulin superfamily member 3 chr1 Not Cancer Driver No 1 hippie, biogrid 184 224 34 34 0
IGSF9 IGSF9 Q9P2J2 Protein turtle homolog A chr1 Not Cancer Driver No 1 hippie, biogrid 167 520 56 56 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 Not Cancer Driver No 1 hippie, biogrid 108 207 38 38 1
IL17RA IL17RA Q96F46 Interleukin-17 receptor A chr22 Not Cancer Driver No 1 hippie, biogrid 92 301 20 20 0
IL25 IL25 Q9H293 Interleukin-25 chr14 Not Cancer Driver No 1 hippie, biogrid 30 50 8 8 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 Not Cancer Driver No 1 hippie 55 165 23 23 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 Census, Compendium Yes 2 hippie, biogrid 102 315 40 40 2
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 Not Cancer Driver No 1 hippie, biogrid 18 34 12 12 3
INSR INSR P06213 Insulin receptor chr19 Not Cancer Driver No 1 hippie, biogrid 190 280 57 57 64
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 Not Cancer Driver No 1 hippie 72 88 8 8 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 Not Cancer Driver No 1 hippie, biogrid 156 107 13 13 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 Not Cancer Driver No 1 hippie, biogrid 166 26 0 0 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 Not Cancer Driver No 1 hippie, biogrid 254 97 27 27 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 Not Cancer Driver No 1 hippie, biogrid 127 201 29 29 0
ITGA6_ENST00000442250 ITGA6 P23229 Integrin alpha-6 chr2 Not Cancer Driver No 1 hippie, biogrid 130 226 29 29 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 Not Cancer Driver No 1 hippie, biogrid 292 114 26 26 1
ITGAV ITGAV P06756 Integrin alpha-V chr2 Census Yes 1 hippie, biogrid 153 92 9 9 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 Not Cancer Driver No 2 hippie, biogrid 103 84 10 10 0
ITGB5 ITGB5 P18084 Integrin beta-5 chr3 Not Cancer Driver No 1 hippie, biogrid 86 27 3 3 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 Not Cancer Driver No 1 hippie, biogrid 182 172 20 20 52
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 Not Cancer Driver No 1 hippie, biogrid 126 158 24 24 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 Census Yes 1 hippie, biogrid 97 327 47 47 0
KIAA0319L KIAA0319L Q8IZA0 Dyslexia-associated protein KIAA0319-like protein chr1 Not Cancer Driver No 1 hippie, biogrid 117 508 58 58 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 Not Cancer Driver No 1 hippie, biogrid 69 75 16 16 0
KPTN KPTN Q9Y664 KICSTOR complex protein kaptin chr19 Not Cancer Driver No 1 hippie, biogrid 44 21 2 2 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX Not Cancer Driver No 1 hippie, biogrid 228 442 75 75 54
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 Not Cancer Driver No 1 hippie, biogrid 47 208 11 11 0
LAMA1 LAMA1 P25391 Laminin subunit alpha-1 chr18 Not Cancer Driver No 1 hippie, biogrid 600 329 71 71 0
LAMA3 LAMA3 Q16787 Laminin subunit alpha-3 chr18 Not Cancer Driver No 1 hippie, biogrid 478 743 98 98 0
LAMA4 LAMA4 Q16363 Laminin subunit alpha-4 chr6 Not Cancer Driver No 1 hippie, biogrid 323 486 87 87 1
LAMA5 LAMA5 O15230 Laminin subunit alpha-5 chr20 Not Cancer Driver No 1 hippie, biogrid 431 701 90 90 0
LAMB1 LAMB1 P07942 Laminin subunit beta-1 chr7 Not Cancer Driver No 1 hippie, biogrid 240 418 50 50 0
LAMB2 LAMB2 P55268 Laminin subunit beta-2 chr3 Not Cancer Driver No 1 hippie, biogrid 234 463 67 67 9
LAMB3_ENST00000367030 LAMB3 Q13751 Laminin subunit beta-3 chr1 Not Cancer Driver No 1 hippie, biogrid 226 376 66 66 4
LAMC1 LAMC1 P11047 Laminin subunit gamma-1 chr1 Not Cancer Driver No 1 hippie, biogrid 232 562 94 94 0
LAMC2 LAMC2 Q13753 Laminin subunit gamma-2 chr1 Not Cancer Driver No 1 hippie, biogrid 165 496 68 68 0
LAMC3 LAMC3 Q9Y6N6 Laminin subunit gamma-3 chr9 Not Cancer Driver No 1 hippie, biogrid 243 422 49 49 1
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX Not Cancer Driver No 1 hippie 43 55 7 7 1
LEPR LEPR P48357 Leptin receptor chr1 Not Cancer Driver No 1 hippie, biogrid 243 57 11 11 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 Not Cancer Driver No 1 hippie, biogrid 57 112 19 19 0
LIFR_ENST00000453190 LIFR P42702 Leukemia inhibitory factor receptor chr5 Census, Compendium Yes 1 hippie, biogrid 247 259 56 56 1
LINGO1 LINGO1 Q96FE5 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 chr15 Not Cancer Driver No 1 hippie, biogrid 130 37 10 10 2
LIPA LIPA P38571 Lysosomal acid lipase/cholesteryl ester hydrolase chr10 Not Cancer Driver No 1 hippie, biogrid 44 12 1 1 4
LMF2 LMF2 Q9BU23 Lipase maturation factor 2 chr22 Not Cancer Driver No 1 hippie, biogrid 75 78 17 17 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 Not Cancer Driver No 1 hippie, biogrid 115 103 8 8 0
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 Not Cancer Driver No 1 hippie, biogrid 134 39 4 4 0
LRFN3 LRFN3 Q9BTN0 Leucine-rich repeat and fibronectin type-III domain-containing protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 77 212 20 20 0
LRFN4 LRFN4 Q6PJG9 Leucine-rich repeat and fibronectin type-III domain-containing protein 4 chr11 Not Cancer Driver No 1 hippie, biogrid 51 168 13 13 0
LRIG1 LRIG1 Q96JA1 Leucine-rich repeats and immunoglobulin-like domains protein 1 chr3 Not Cancer Driver No 1 hippie, biogrid 156 352 49 49 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 Not Cancer Driver No 1 hippie, biogrid 131 231 30 30 0
LRIG3 LRIG3 Q6UXM1 Leucine-rich repeats and immunoglobulin-like domains protein 3 chr12 Census, Compendium Yes 1 hippie, biogrid 143 230 31 31 0
LRP10 LRP10 Q7Z4F1 Low-density lipoprotein receptor-related protein 10 chr14 Not Cancer Driver No 1 hippie, biogrid 99 237 32 32 0
LRP1B LRP1B Q9NZR2 Low-density lipoprotein receptor-related protein 1B chr2 Census, Compendium Yes 1 hippie, biogrid 1727 177 78 78 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 Not Cancer Driver No 1 hippie, biogrid 998 209 40 40 1
LTBP4 LTBP4 Q8N2S1 Latent-transforming growth factor beta-binding protein 4 chr19 Not Cancer Driver No 1 hippie, biogrid 191 432 42 42 1
LYRM4_ENST00000330636 LYRM4 Q9HD34 LYR motif-containing protein 4 chr6 Not Cancer Driver No 1 hippie, biogrid 14 11 1 1 1
MAN2B1 MAN2B1 O00754 Lysosomal alpha-mannosidase chr19 Not Cancer Driver No 1 hippie, biogrid 139 145 21 21 40
MAN2B2 MAN2B2 Q9Y2E5 Epididymis-specific alpha-mannosidase chr4 Not Cancer Driver No 1 hippie, biogrid 135 153 23 23 0
MANBA MANBA O00462 Beta-mannosidase chr4 Not Cancer Driver No 1 hippie, biogrid 108 10 0 0 3
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 Not Cancer Driver No 1 intact, hippie 128 750 126 126 18
MCAM MCAM P43121 Cell surface glycoprotein MUC18 chr11 Not Cancer Driver No 1 hippie, biogrid 91 305 46 46 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 363 476 59 59 3
MERTK_ENST00000421804 MERTK Q12866 Tyrosine-protein kinase Mer chr2 Not Cancer Driver No 1 hippie, biogrid 175 159 31 31 3
MEST MEST Q5EB52 Mesoderm-specific transcript homolog protein chr7 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 Census, Compendium Yes 1 hippie, biogrid 226 62 15 15 19
MGMT MGMT B4DEE8 Methylated-DNA--protein-cysteine methyltransferase chr10 Census Yes 1 hippie 43 40 15 15 0
MGRN1_ENST00000399577 MGRN1 O60291 E3 ubiquitin-protein ligase MGRN1 chr16 Not Cancer Driver No 1 hippie, biogrid 76 228 37 37 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 222 1490 178 178 0
MINPP1 MINPP1 Q9UNW1 Multiple inositol polyphosphate phosphatase 1 chr10 Not Cancer Driver No 1 hippie, biogrid 52 46 2 2 2
MMD MMD Q15546 Monocyte to macrophage differentiation factor chr17 Not Cancer Driver No 1 hippie 30 0 0 0 0
MRC2 MRC2 Q9UBG0 C-type mannose receptor 2 chr17 Not Cancer Driver No 1 hippie, biogrid 185 256 36 36 0
MYORG MYORG Q6NSJ0 Myogenesis-regulating glycosidase chr9 Not Cancer Driver No 1 hippie 88 60 3 3 2
NAAA NAAA Q02083 N-acylethanolamine-hydrolyzing acid amidase chr4 Not Cancer Driver No 1 hippie, biogrid 42 43 3 3 0
NAGLU NAGLU P54802 Alpha-N-acetylglucosaminidase chr17 Not Cancer Driver No 1 hippie, biogrid 70 18 1 1 68
NCLN NCLN Q969V3 Nicalin chr19 Not Cancer Driver No 1 hippie, biogrid 42 38 4 4 0
NCSTN NCSTN Q92542 Nicastrin chr1 Not Cancer Driver No 1 hippie, biogrid 94 72 11 11 1
NECTIN3 NECTIN3 Q9NQS3 Nectin-3 chr3 Not Cancer Driver No 2 intact, hippie 72 106 9 9 0
NEDD8 NEDD8 Q15843 NEDD8 chr14 Not Cancer Driver No 1 hippie 10 36 5 5 0
NELL2_ENST00000452445 NELL2 Q99435 Protein kinase C-binding protein NELL2 chr12 Not Cancer Driver No 1 hippie, biogrid 194 15 4 4 0
NFS1 NFS1 Q9Y697 Cysteine desulfurase, mitochondrial chr20 Not Cancer Driver No 1 hippie, biogrid 46 72 9 9 1
NID1 NID1 P14543 Nidogen-1 chr1 Not Cancer Driver No 1 hippie, biogrid 246 340 72 72 0
NID2 NID2 Q14112 Nidogen-2 chr14 Not Cancer Driver No 1 hippie, biogrid 270 415 96 96 0
NOMO1 NOMO1 Q15155 Nodal modulator 1 chr16 Not Cancer Driver No 1 hippie, biogrid 130 128 23 23 0
NOMO3 NOMO3 P69849 Nodal modulator 3 chr16 Not Cancer Driver No 1 hippie, biogrid 44 129 3 3 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 Census, Compendium Yes 1 hippie, biogrid 363 686 87 87 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 Census, Compendium Yes 1 hippie, biogrid 282 630 77 77 1
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 Not Cancer Driver No 1 hippie, biogrid 306 557 81 81 110
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie, biogrid 155 24 0 0 150
NPTX2 NPTX2 P47972 Neuronal pentraxin-2 chr7 Not Cancer Driver No 1 hippie, biogrid 78 165 10 10 0
NPTXR_ENST00000640136 NPTXR O95502 Neuronal pentraxin receptor chr22 Not Cancer Driver No 1 hippie, biogrid 59 207 14 14 0
NTM_ENST00000374786 NTM Q9P121 Neurotrimin chr11 Not Cancer Driver No 3 intact, hippie, biogrid 126 48 14 14 0
NUP210 NUP210 Q8TEM1 Nuclear pore membrane glycoprotein 210 chr3 Not Cancer Driver No 1 hippie, biogrid 262 156 19 19 0
OLFM2 OLFM2 O95897 Noelin-2 chr19 Not Cancer Driver No 1 hippie, biogrid 74 16 2 2 0
OPCML OPCML Q14982 Opioid-binding protein/cell adhesion molecule chr11 Not Cancer Driver No 2 hippie, biogrid 125 36 18 18 1
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 Not Cancer Driver No 1 hippie, biogrid 105 401 37 37 0
OSMR OSMR Q99650 Oncostatin-M-specific receptor subunit beta chr5 Not Cancer Driver No 1 hippie, biogrid 167 145 22 22 5
OSTM1 OSTM1 Q86WC4 Osteopetrosis-associated transmembrane protein 1 chr6 Not Cancer Driver No 1 hippie, biogrid 31 24 4 4 0
PAX4_ENST00000378740 PAX4 O43316 Paired box protein Pax-4 chr7 Not Cancer Driver No 1 intact, hippie 77 138 39 39 4
PCDH9 PCDH9 Q9HC56 Protocadherin-9 chr13 Not Cancer Driver No 1 hippie, biogrid 313 620 169 169 0
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 Not Cancer Driver No 1 hippie, biogrid 319 168 25 25 0
PCYOX1 PCYOX1 Q9UHG3 Prenylcysteine oxidase 1 chr2 Not Cancer Driver No 1 hippie, biogrid 60 9 1 1 0
PCYOX1L PCYOX1L Q8NBM8 Prenylcysteine oxidase-like chr5 Not Cancer Driver No 1 hippie, biogrid 61 0 0 0 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 Not Cancer Driver No 1 hippie 86 464 54 54 12
PFDN6_ENST00000374610 PFDN6 O15212 Prefoldin subunit 6 chr6 Not Cancer Driver No 1 intact, hippie 14 57 8 8 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 Not Cancer Driver No 1 hippie, biogrid 122 471 26 26 12
PIGK PIGK Q92643 GPI-anchor transamidase chr1 Not Cancer Driver No 1 hippie, biogrid 54 37 9 9 5
PIGS PIGS Q96S52 GPI transamidase component PIG-S chr17 Not Cancer Driver No 1 hippie, biogrid 59 32 4 4 2
PIGT PIGT Q969N2 GPI transamidase component PIG-T chr20 Not Cancer Driver No 1 hippie, biogrid 51 36 6 6 1
PIGU PIGU Q9H490 Phosphatidylinositol glycan anchor biosynthesis class U protein chr20 Not Cancer Driver No 1 hippie, biogrid 47 0 0 0 2
PKD2 PKD2 Q13563 Polycystin-2 chr4 Not Cancer Driver No 1 hippie, biogrid 113 375 35 35 10
PLA2G15 PLA2G15 Q8NCC3 Phospholipase A2 group XV chr16 Not Cancer Driver No 1 hippie, biogrid 61 11 3 3 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 Not Cancer Driver No 1 hippie, biogrid 89 15 2 2 0
PLBD2 PLBD2 Q8NHP8 Putative phospholipase B-like 2 chr12 Not Cancer Driver No 1 hippie, biogrid 57 29 6 6 0
PLOD3 PLOD3 O60568 Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 chr7 Not Cancer Driver No 1 hippie, biogrid 108 65 8 8 1
PLTP PLTP P55058 Phospholipid transfer protein chr20 Not Cancer Driver No 1 hippie, biogrid 78 27 6 6 0
PLXNA1 PLXNA1 Q9UIW2 Plexin-A1 chr3 Not Cancer Driver No 1 hippie, biogrid 281 228 28 28 0
PLXNA2 PLXNA2 O75051 Plexin-A2 chr1 Not Cancer Driver No 1 hippie, biogrid 312 142 25 25 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX Not Cancer Driver No 1 hippie, biogrid 243 199 34 34 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 Not Cancer Driver No 1 hippie, biogrid 273 304 35 35 0
PLXNC1 PLXNC1 O60486 Plexin-C1 chr12 Not Cancer Driver No 1 hippie, biogrid 205 135 18 18 0
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 Not Cancer Driver No 1 hippie, biogrid 246 321 35 35 0
POFUT1 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 Not Cancer Driver No 1 hippie, biogrid 56 17 2 2 0
POGLUT1 POGLUT1 Q8NBL1 Protein O-glucosyltransferase 1 chr3 Not Cancer Driver No 1 hippie, biogrid 57 0 0 0 3
POMGNT2_ENST00000441964 POMGNT2 Q8NAT1 Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 chr3 Not Cancer Driver No 1 hippie, biogrid 65 23 6 6 3
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 hippie, biogrid 53 30 9 9 3
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 Not Cancer Driver No 1 hippie, biogrid 75 55 5 5 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 Not Cancer Driver No 1 hippie, biogrid 84 60 3 3 15
PPT2_ENST00000395523 PPT2 Q9UMR5 Lysosomal thioesterase PPT2 chr6 Compendium Yes 1 hippie, biogrid 45 0 0 0 0
PRCP_ENST00000313010 PRCP P42785 Lysosomal Pro-X carboxypeptidase chr11 Not Cancer Driver No 1 hippie, biogrid 58 0 0 0 0
PRELP PRELP P51888 Prolargin chr1 Not Cancer Driver No 1 hippie, biogrid 63 55 13 13 0
PRNP PRNP P04156 Major prion protein chr20 Not Cancer Driver No 1 hippie 36 115 7 7 18
PTGFRN PTGFRN Q9P2B2 Prostaglandin F2 receptor negative regulator chr1 Not Cancer Driver No 1 hippie, biogrid 122 121 16 16 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 Not Cancer Driver No 1 hippie, biogrid 212 465 61 61 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 Not Cancer Driver No 1 hippie, biogrid 184 401 61 61 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 Census, Compendium Yes 1 hippie, biogrid 292 302 57 57 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 Not Cancer Driver No 1 hippie, biogrid 250 829 111 111 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 Not Cancer Driver No 1 hippie, biogrid 248 325 64 64 0
PVR PVR P15151 Poliovirus receptor chr19 Not Cancer Driver No 1 hippie, biogrid 39 120 19 19 0
PXDN PXDN Q92626 Peroxidasin homolog chr2 Not Cancer Driver No 1 hippie, biogrid 332 307 77 77 1
QSOX1 QSOX1 O00391 Sulfhydryl oxidase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 93 189 22 22 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 Not Cancer Driver No 1 hippie 10 18 1 1 0
RNASET2_ENST00000476238 RNASET2 O00584 Ribonuclease T2 chr6 Not Cancer Driver No 3 hippie, biogrid 32 37 3 3 1
RNF157 RNF157 Q96PX1 E3 ubiquitin ligase RNF157 chr17 Not Cancer Driver No 1 hippie, biogrid 76 375 39 39 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 Not Cancer Driver No 1 hippie, biogrid 353 1122 234 234 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 1 hippie, biogrid 145 732 81 81 0
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 Not Cancer Driver No 1 hippie, biogrid 145 329 36 36 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 Not Cancer Driver No 1 hippie, biogrid 80 230 29 29 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 Not Cancer Driver No 1 hippie, biogrid 53 6 1 1 0
SDK2 SDK2 Q58EX2 Protein sidekick-2 chr17 Not Cancer Driver No 1 hippie, biogrid 330 850 131 131 0
SEC11A_ENST00000268220 SEC11A P67812 Signal peptidase complex catalytic subunit SEC11A chr15 Not Cancer Driver No 1 hippie, biogrid 20 0 0 0 0
SEL1L3 SEL1L3 Q68CR1 Protein sel-1 homolog 3 chr4 Not Cancer Driver No 1 hippie, biogrid 156 77 2 2 0
SELENON SELENON Q9NZV5 Selenoprotein N chr1 Not Cancer Driver No 1 hippie 53 93 5 5 11
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 Not Cancer Driver No 1 hippie, biogrid 136 111 23 23 0
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 Not Cancer Driver No 1 hippie, biogrid 94 107 17 17 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 Not Cancer Driver No 1 hippie, biogrid 111 149 27 27 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 Not Cancer Driver No 1 hippie, biogrid 117 132 15 15 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 Not Cancer Driver No 1 hippie, biogrid 95 285 30 30 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 Not Cancer Driver No 1 hippie, biogrid 136 456 72 72 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 Not Cancer Driver No 1 hippie, biogrid 77 340 26 26 0
SERPINA1 SERPINA1 P01009 Alpha-1-antitrypsin chr14 Not Cancer Driver No 1 hippie 66 38 7 7 0
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 Not Cancer Driver No 2 hippie, biogrid 103 24 17 17 0
SERPINA9_ENST00000380365 SERPINA9 Q86WD7 Serpin A9 chr14 Not Cancer Driver No 1 hippie, biogrid 96 25 6 6 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 Not Cancer Driver No 1 hippie, biogrid 62 0 0 0 0
SEZ6L2_ENST00000308713 SEZ6L2 Q6UXD5 Seizure 6-like protein 2 chr16 Not Cancer Driver No 1 hippie, biogrid 161 433 92 92 0
SGSH SGSH P51688 N-sulphoglucosamine sulphohydrolase chr17 Not Cancer Driver No 1 hippie, biogrid 45 44 2 2 56
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 Not Cancer Driver No 1 hippie, biogrid 51 32 7 7 0
SIAE SIAE Q9HAT2 Sialate O-acetylesterase chr11 Not Cancer Driver No 1 hippie, biogrid 53 10 3 3 9
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 19 95 17 17 0
SLAMF7 SLAMF7 Q9NQ25 SLAM family member 7 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 66 53 14 14 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 Not Cancer Driver No 1 hippie, biogrid 153 202 23 23 0
SLC4A7_ENST00000295736 SLC4A7 Q9Y6M7 Sodium bicarbonate cotransporter 3 chr3 Not Cancer Driver No 1 hippie, biogrid 165 406 57 57 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 Not Cancer Driver No 1 hippie, biogrid 428 31 13 13 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SNED1 SNED1 Q8TER0 Sushi, nidogen and EGF-like domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie, biogrid 147 325 33 33 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 Not Cancer Driver No 1 hippie, biogrid 374 87 10 10 0
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 Not Cancer Driver No 1 hippie, biogrid 63 75 12 12 0
ST14 ST14 Q9Y5Y6 Suppressor of tumorigenicity 14 protein chr11 Not Cancer Driver No 1 hippie, biogrid 106 47 5 5 1
ST6GALNAC4 ST6GALNAC4 Q9H4F1 Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase chr9 Not Cancer Driver No 1 hippie, biogrid 34 0 0 0 0
ST6GALNAC5 ST6GALNAC5 Q9BVH7 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 chr1 Not Cancer Driver No 3 hippie, biogrid 91 94 25 25 0
ST8SIA4 ST8SIA4 Q92187 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase chr5 Not Cancer Driver No 1 hippie, biogrid 95 5 1 1 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 Not Cancer Driver No 1 hippie 35 112 14 14 12
SUCO_ENST00000263688 SUCO Q9UBS9 SUN domain-containing ossification factor chr1 Not Cancer Driver No 1 hippie, biogrid 164 785 99 99 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 Not Cancer Driver No 1 hippie, biogrid 246 269 71 71 0
SULF2_ENST00000484875 SULF2 Q8IWU5 Extracellular sulfatase Sulf-2 chr20 Not Cancer Driver No 1 hippie, biogrid 145 142 18 18 0
SUMF1 SUMF1 Q8NBK3 Formylglycine-generating enzyme chr3 Not Cancer Driver No 1 hippie, biogrid 41 141 15 15 16
SUN1 SUN1 O94901 SUN domain-containing protein 1 chr7 Not Cancer Driver No 1 hippie, biogrid 109 246 26 26 0
SUSD1_ENST00000374270 SUSD1 Q6UWL2 Sushi domain-containing protein 1 chr9 Not Cancer Driver No 1 hippie, biogrid 80 45 8 8 0
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 Not Cancer Driver No 1 hippie, biogrid 779 1888 220 220 1
TAPBP_ENST00000434618 TAPBP O15533 Tapasin chr6 Not Cancer Driver No 1 hippie, biogrid 58 168 26 26 0
TCTN2 TCTN2 Q96GX1 Tectonic-2 chr12 Not Cancer Driver No 1 hippie, biogrid 75 23 2 2 0
TENM3 TENM3 Q9P273 Teneurin-3 chr4 Not Cancer Driver No 1 hippie, biogrid 618 484 112 112 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 Not Cancer Driver No 1 hippie, biogrid 41 41 4 4 10
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 Not Cancer Driver No 1 hippie, biogrid 129 268 41 41 0
THSD4 THSD4 Q6ZMP0 Thrombospondin type-1 domain-containing protein 4 chr15 Not Cancer Driver No 1 hippie, biogrid 172 410 62 62 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX Not Cancer Driver No 1 hippie, biogrid 25 0 0 0 0
TINAGL1 TINAGL1 Q9GZM7 Tubulointerstitial nephritis antigen-like chr1 Not Cancer Driver No 1 hippie, biogrid 62 89 15 15 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 Not Cancer Driver No 1 hippie, biogrid 31 13 3 3 0
TMED4 TMED4 Q7Z7H5 Transmembrane emp24 domain-containing protein 4 chr7 Not Cancer Driver No 1 hippie, biogrid 20 34 2 2 0
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 16 22 2 2 0
TMEM131 TMEM131 Q92545 Transmembrane protein 131 chr2 Not Cancer Driver No 1 hippie, biogrid 258 765 118 118 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 Not Cancer Driver No 1 hippie 188 448 47 47 0
TMEM231 TMEM231 Q9H6L2 Transmembrane protein 231 chr16 Not Cancer Driver No 1 hippie, biogrid 15 16 1 1 2
TMEM25_ENST00000313236 TMEM25 Q86YD3 Transmembrane protein 25 chr11 Not Cancer Driver No 1 hippie, biogrid 50 128 11 11 0
TMEM39A TMEM39A Q9NV64 Transmembrane protein 39A chr3 Not Cancer Driver No 1 hippie, biogrid 53 14 1 1 0
TMPRSS11B TMPRSS11B Q86T26 Transmembrane protease serine 11B chr4 Not Cancer Driver No 2 hippie, biogrid 95 5 0 0 0
TMTC3 TMTC3 Q6ZXV5 Protein O-mannosyl-transferase TMTC3 chr12 Not Cancer Driver No 1 hippie, biogrid 122 84 7 7 2
TOR1A TOR1A O14656 Torsin-1A chr9 Not Cancer Driver No 1 hippie 33 0 0 0 3
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 71 401 44 44 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 Not Cancer Driver No 1 hippie, biogrid 58 13 1 1 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
TTC13 TTC13 Q8NBP0 Tetratricopeptide repeat protein 13 chr1 Not Cancer Driver No 1 hippie, biogrid 128 49 1 1 0
TTC17 TTC17 Q96AE7 Tetratricopeptide repeat protein 17 chr11 Not Cancer Driver No 1 hippie, biogrid 161 276 46 46 0
TXNDC11 TXNDC11 Q6PKC3 Thioredoxin domain-containing protein 11 chr16 Not Cancer Driver No 1 hippie, biogrid 81 179 17 17 0
TXNDC15 TXNDC15 Q96J42 Thioredoxin domain-containing protein 15 chr5 Not Cancer Driver No 1 hippie, biogrid 36 137 15 15 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 Not Cancer Driver No 1 hippie, biogrid 20 102 8 8 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 Not Cancer Driver No 1 hippie 13 14 0 0 0
UBE2D2 UBE2D2 P62837 Ubiquitin-conjugating enzyme E2 D2 chr5 Compendium Yes 1 hippie 19 13 1 1 0
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 Not Cancer Driver No 1 hippie 21 13 4 4 0
UBE2E1 UBE2E1 P51965 Ubiquitin-conjugating enzyme E2 E1 chr3 Not Cancer Driver No 1 hippie 21 78 10 10 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 Not Cancer Driver No 1 hippie 19 32 4 4 0
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 Not Cancer Driver No 1 hippie, biogrid 107 18 2 2 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 Not Cancer Driver No 1 hippie, biogrid 155 117 20 20 0
VASN VASN Q6EMK4 Vasorin chr16 Not Cancer Driver No 2 intact, hippie, biogrid 37 233 8 8 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 Not Cancer Driver No 1 hippie 88 186 16 16 16
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 Not Cancer Driver No 1 hippie, biogrid 16 10 0 0 0
VPS36 VPS36 Q86VN1 Vacuolar protein-sorting-associated protein 36 chr13 Not Cancer Driver No 1 hippie, biogrid 35 94 14 14 0
VSTM1 VSTM1 Q6UX27 V-set and transmembrane domain-containing protein 1 chr19 Not Cancer Driver No 1 intact, hippie 72 126 40 40 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie, biogrid 105 203 10 10 39
WNT10B WNT10B O00744 Protein Wnt-10b chr12 Not Cancer Driver No 1 hippie, biogrid 56 84 16 16 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 Not Cancer Driver No 1 hippie, biogrid 93 18 9 9 4
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 Not Cancer Driver No 1 hippie 89 462 63 63 0