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DHCR24 ,DHCR24 ,Q15392
  • Number of Interaction partner in intact: 26
  • Number of Interaction partner in biogrid: 64
  • Number of Interaction partner in hippie: 126
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
AAR2_ENST00000320849 AAR2 Q9Y312 Protein AAR2 homolog chr20 Not Cancer Driver No 1 hippie 56 28 6 6 0
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 Not Cancer Driver No 3 hippie, biogrid 50 39 4 4 17
AGK AGK Q53H12 Acylglycerol kinase, mitochondrial chr7 Not Cancer Driver No 1 hippie 71 77 6 6 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 Not Cancer Driver No 1 hippie 73 229 30 30 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 Not Cancer Driver No 1 hippie 70 54 1 1 0
APOB APOB P04114 Apolipoprotein B-100 chr2 Not Cancer Driver No 1 hippie, biogrid 1022 315 72 72 3
APP APP P05067 Amyloid-beta precursor protein chr21 Not Cancer Driver No 1 intact, hippie 128 418 71 71 17
ARMC8_ENST00000469044 ARMC8 Q8IUR7 Armadillo repeat-containing protein 8 chr3 Not Cancer Driver No 1 hippie 71 7 0 0 0
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 Not Cancer Driver No 2 intact, hippie, biogrid 203 117 24 24 0
ATP13A3_ENST00000256031 ATP13A3 Q9H7F0 Polyamine-transporting ATPase 13A3 chr3 Not Cancer Driver No 1 hippie, biogrid 149 49 11 11 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 Not Cancer Driver No 1 hippie, biogrid 200 115 29 29 31
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 Not Cancer Driver No 1 hippie, biogrid 157 80 11 11 1
ATP2A3_ENST00000397041 ATP2A3 Q93084 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 chr17 Not Cancer Driver No 1 hippie, biogrid 130 147 16 16 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 Not Cancer Driver No 1 hippie 39 11 0 0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 Not Cancer Driver No 1 hippie 14 15 1 1 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 Not Cancer Driver No 2 hippie, biogrid 40 0 0 0 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 Census, Compendium Yes 1 hippie 77 98 16 16 0
BRI3BP BRI3BP Q8WY22 BRI3-binding protein chr12 Not Cancer Driver No 1 hippie, biogrid 30 18 3 3 0
BTF3 BTF3 P20290 Transcription factor BTF3 chr5 Not Cancer Driver No 1 hippie 27 192 24 24 0
C15orf48_ENST00000396650 NMES1 Q9C002 Normal mucosa of esophagus-specific gene 1 protein chr15 Not Cancer Driver No 1 intact 14 10 1 1 0
CAV2 CAV2 P51636 Caveolin-2 chr7 Not Cancer Driver No 2 intact, hippie, biogrid 20 5 2 2 0
CCR4 CCR4 P51679 C-C chemokine receptor type 4 chr3 Census Yes 1 intact, hippie 45 0 0 0 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 Census Yes 1 hippie 29 54 9 9 0
CD81 CD81 P60033 CD81 antigen chr11 Not Cancer Driver No 1 hippie 28 0 0 0 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 Not Cancer Driver No 1 intact, hippie 24 114 21 21 1
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 Not Cancer Driver No 1 intact, hippie 198 634 64 64 0
CNR2 CNR2 P34972 Cannabinoid receptor 2 chr1 Not Cancer Driver No 1 intact, hippie 57 21 4 4 0
COQ10A COQ10A Q96MF6 Coenzyme Q-binding protein COQ10 homolog A, mitochondrial chr12 Not Cancer Driver No 1 hippie 27 28 0 0 0
COQ9 COQ9 O75208 Ubiquinone biosynthesis protein COQ9, mitochondrial chr16 Not Cancer Driver No 1 intact, hippie, biogrid 43 111 13 13 0
COX6B1_ENST00000592141 COX6B1 P14854 Cytochrome c oxidase subunit 6B1 chr19 Not Cancer Driver No 1 hippie 15 23 6 6 2
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 Not Cancer Driver No 1 intact, hippie 42 123 9 9 1
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 Not Cancer Driver No 1 hippie, biogrid 28 11 1 1 0
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 Not Cancer Driver No 1 hippie 85 7 1 1 53
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 Not Cancer Driver No 1 intact, hippie 132 514 82 82 0
EFTUD2 EFTUD2 Q15029 116 kDa U5 small nuclear ribonucleoprotein component chr17 Compendium Yes 1 hippie 132 179 30 30 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 Census, Compendium Yes 1 hippie 444 223 35 35 1
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
ENDOD1 ENDOD1 O94919 Endonuclease domain-containing 1 protein chr11 Not Cancer Driver No 1 hippie, biogrid 51 72 9 9 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 Not Cancer Driver No 3 intact, hippie, biogrid 78 70 2 2 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 Not Cancer Driver No 1 hippie 54 0 0 0 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 Not Cancer Driver No 1 hippie, biogrid 45 2 0 0 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 96 26 5 5 0
FUNDC1 FUNDC1 Q8IVP5 FUN14 domain-containing protein 1 chrX Not Cancer Driver No 1 hippie, biogrid 16 24 2 2 0
FUNDC2 FUNDC2 Q9BWH2 FUN14 domain-containing protein 2 chrX Not Cancer Driver No 2 hippie, biogrid 28 34 3 3 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie, biogrid 92 70 13 13 0
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 Not Cancer Driver No 1 hippie 74 38 5 5 171
GP5 GP5 P40197 Platelet glycoprotein V chr3 Not Cancer Driver No 1 hippie, biogrid 81 57 5 5 0
GPR182 GPR182 O15218 G-protein coupled receptor 182 chr12 Not Cancer Driver No 1 hippie, biogrid 49 33 4 4 0
GPR45 GPR45 Q9Y5Y3 Probable G-protein coupled receptor 45 chr2 Not Cancer Driver No 1 hippie, biogrid 97 0 0 0 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 Not Cancer Driver No 1 intact 84 112 12 12 0
HRAS HRAS P01112 GTPase HRas chr11 Census, Compendium Yes 2 intact, hippie, biogrid 107 16 4 4 18
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 28 3 0 0 0
HSD3B7 HSD3B7 Q9H2F3 3 beta-hydroxysteroid dehydrogenase type 7 chr16 Not Cancer Driver No 1 hippie, biogrid 43 27 5 5 2
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 Not Cancer Driver No 1 hippie, biogrid 69 18 5 5 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 Census, Compendium Yes 1 intact, hippie 106 211 31 31 1
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 Not Cancer Driver No 1 intact, hippie 12 24 2 2 0
ITFG1 ITFG1 Q8TB96 T-cell immunomodulatory protein chr16 Not Cancer Driver No 1 hippie 70 18 3 3 0
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 65 21 4 4 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 Not Cancer Driver No 1 hippie 222 774 102 102 2
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 Not Cancer Driver No 1 hippie 57 4 0 0 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 79 21 6 6 0
LPAR2_ENST00000586703 LPAR2 Q9HBW0 Lysophosphatidic acid receptor 2 chr19 Not Cancer Driver No 1 hippie, biogrid 47 2 0 0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 intact, hippie 519 90 17 17 23
LUZP1_ENST00000418342 LUZP1 Q86V48 Leucine zipper protein 1 chr1 Not Cancer Driver No 3 intact, hippie, biogrid 102 972 91 91 0
MFSD4A MFSD4A Q8N468 Major facilitator superfamily domain-containing protein 4A chr1 Not Cancer Driver No 1 hippie 56 29 3 3 0
NANOG NANOG Q9H9S0 Homeobox protein NANOG chr12 Not Cancer Driver No 1 hippie 46 169 35 35 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 Not Cancer Driver No 1 hippie, biogrid 14 4 0 0 0
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 Not Cancer Driver No 2 hippie, biogrid 14 46 4 4 2
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 Not Cancer Driver No 1 hippie 155 24 0 0 150
NUBPL NUBPL Q8TB37 Iron-sulfur protein NUBPL chr14 Not Cancer Driver No 1 hippie, biogrid 32 49 1 1 2
NUP155 NUP155 O75694 Nuclear pore complex protein Nup155 chr5 Not Cancer Driver No 1 hippie, biogrid 154 221 19 19 1
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 60 16 1 1 0
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 Not Cancer Driver No 1 hippie, biogrid 67 60 13 13 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 Not Cancer Driver No 1 hippie, biogrid 54 45 7 7 2
PGR PGR P06401 Progesterone receptor chr11 Not Cancer Driver No 1 intact, hippie 161 480 55 55 0
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX Not Cancer Driver No 1 hippie 30 74 16 16 0
PI4KB_ENST00000368873 PI4KB Q9UBF8 Phosphatidylinositol 4-kinase beta chr1 Not Cancer Driver No 1 hippie 93 311 34 34 0
PIGH PIGH Q14442 Phosphatidylinositol N-acetylglucosaminyltransferase subunit H chr14 Not Cancer Driver No 1 hippie, biogrid 12 1 0 0 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 Not Cancer Driver No 1 intact, hippie, biogrid 53 30 9 9 3
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 Census Yes 1 hippie 36 186 12 12 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 Not Cancer Driver No 1 intact, hippie 61 134 21 21 96
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 Not Cancer Driver No 1 hippie 23 67 6 6 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 Not Cancer Driver No 1 hippie 49 140 25 25 0
PTPN5 PTPN5 P54829 Tyrosine-protein phosphatase non-receptor type 5 chr11 Not Cancer Driver No 1 hippie 101 163 32 32 0
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 Not Cancer Driver No 1 hippie, biogrid 37 1 0 0 1
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 Not Cancer Driver No 1 hippie 202 578 75 75 0
REEP5 REEP5 Q00765 Receptor expression-enhancing protein 5 chr5 Not Cancer Driver No 2 hippie, biogrid 34 0 0 0 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 Census, Compendium Yes 1 hippie 208 105 12 12 139
RHOA RHOA P61586 Transforming protein RhoA chr3 Census, Compendium Yes 1 hippie 99 46 13 13 2
RNF4 RNF4 P78317 E3 ubiquitin-protein ligase RNF4 chr4 Not Cancer Driver No 1 hippie 14 117 7 7 0
RTN1 RTN1 Q16799 Reticulon-1 chr14 Not Cancer Driver No 1 hippie, biogrid 177 573 134 134 0
RTN3 RTN3 O95197 Reticulon-3 chr11 Not Cancer Driver No 1 hippie, biogrid 132 707 87 87 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 Not Cancer Driver No 1 hippie, biogrid 121 866 82 82 0
SEC61B SEC61B P60468 Protein transport protein Sec61 subunit beta chr9 Not Cancer Driver No 1 hippie, biogrid 11 60 7 7 0
SIGMAR1 SIGMAR1 Q99720 Sigma non-opioid intracellular receptor 1 chr9 Not Cancer Driver No 1 hippie, biogrid 22 2 0 0 1
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 Not Cancer Driver No 1 hippie, biogrid 141 297 18 18 8
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 Not Cancer Driver No 1 intact, hippie 63 43 1 1 0
SLC16A11 SLC16A11 Q8NCK7 Monocarboxylate transporter 11 chr17 Not Cancer Driver No 1 hippie 33 72 5 5 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 Not Cancer Driver No 1 hippie, biogrid 69 17 4 4 1
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 Not Cancer Driver No 1 hippie, biogrid 51 13 2 2 48
SLC30A7_ENST00000357650 SLC30A7 Q8NEW0 Zinc transporter 7 chr1 Not Cancer Driver No 1 hippie, biogrid 32 46 2 2 0
SLC38A1_ENST00000546893 SLC38A1 Q9H2H9 Sodium-coupled neutral amino acid transporter 1 chr12 Not Cancer Driver No 1 intact, hippie 95 25 4 4 0
SLC4A2 SLC4A2 P04920 Anion exchange protein 2 chr7 Not Cancer Driver No 1 hippie, biogrid 150 509 62 62 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SPPL2B SPPL2B Q8TCT7 Signal peptide peptidase-like 2B chr19 Not Cancer Driver No 1 hippie, biogrid 68 99 17 17 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie, biogrid 131 144 25 25 26
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 Not Cancer Driver No 1 hippie 77 456 63 63 0
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 Not Cancer Driver No 1 hippie, biogrid 70 387 45 45 13
SYNGR1 SYNGR1 O43759 Synaptogyrin-1 chr22 Not Cancer Driver No 1 hippie, biogrid 26 48 5 5 0
SYP SYP P08247 Synaptophysin chrX Not Cancer Driver No 1 hippie, biogrid 36 93 8 8 1
TEX101_ENST00000598265 TEX101 Q9BY14 Testis-expressed protein 101 chr19 Not Cancer Driver No 1 intact, hippie 45 2 0 0 0
TMEM41B_ENST00000611268 TMEM41B Q5BJD5 Transmembrane protein 41B chr11 Not Cancer Driver No 1 hippie 19 47 3 3 0
TMEM63A TMEM63A O94886 CSC1-like protein 1 chr1 Not Cancer Driver No 1 hippie, biogrid 87 36 1 1 3
TMPO TMPO P42166 Lamina-associated polypeptide 2, isoform alpha chr12 Not Cancer Driver No 1 hippie 78 412 52 52 0
TMPRSS4_ENST00000437212 TMPRSS4 Q9NRS4 Transmembrane protease serine 4 chr11 Not Cancer Driver No 1 hippie, biogrid 47 35 4 4 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 1 hippie 2891 282 1466 1466 83
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 Not Cancer Driver No 1 hippie, biogrid 29 0 0 0 0
TTYH1_ENST00000376530 TTYH1 Q9H313 Protein tweety homolog 1 chr19 Not Cancer Driver No 1 hippie, biogrid 56 21 3 3 0
UBL4A UBL4A P11441 Ubiquitin-like protein 4A chrX Not Cancer Driver No 1 hippie 22 16 5 5 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX Not Cancer Driver No 1 hippie 82 581 79 79 8
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 Not Cancer Driver No 1 intact, hippie 57 127 5 5 0
VIPR1 VIPR1 P32241 Vasoactive intestinal polypeptide receptor 1 chr3 Not Cancer Driver No 1 hippie, biogrid 41 10 2 2 0
VIPR2 VIPR2 P41587 Vasoactive intestinal polypeptide receptor 2 chr7 Not Cancer Driver No 1 hippie, biogrid 74 0 0 0 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 Not Cancer Driver No 1 hippie, biogrid 30 35 3 3 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 Not Cancer Driver No 1 hippie, biogrid 105 203 10 10 39
WWP2 WWP2 O00308 NEDD4-like E3 ubiquitin-protein ligase WWP2 chr16 Not Cancer Driver No 1 hippie 112 422 57 57 0