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CDK11A ,CDK11A ,Q9UQ88
  • Uniprot Accession= Q9UQ88
  • Ensembl Transcript= ENST00000378633.5
  • Uniprot Name= CDK11A
  • Name= Cyclin-dependent kinase 11A
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of Interaction partner in intact: 30
  • Number of Interaction partner in biogrid: 61
  • Number of Interaction partner in hippie: 121
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
A2M A2M P01023 Alpha-2-macroglobulin chr12 Not Cancer Driver No 1 hippie 260 144 22 22 0
AHSG AHSG P02765 Alpha-2-HS-glycoprotein chr3 Not Cancer Driver No 1 intact, hippie, biogrid 74 131 41 41 0
AL662899.2_ENST00000375880 CSNK2B Q5SRQ3 Casein kinase II subunit beta chr6 Not Cancer Driver No 2 hippie, biogrid 21 30 1 1 0
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 Not Cancer Driver No 1 intact, hippie, biogrid 62 1144 34 34 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 Not Cancer Driver No 1 hippie, biogrid 126 316 31 31 1
AP4M1_ENST00000421755 AP4M1 O00189 AP-4 complex subunit mu-1 chr7 Not Cancer Driver No 1 hippie 63 64 7 7 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 2 hippie, biogrid 34 103 14 14 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 Not Cancer Driver No 1 intact, hippie, biogrid 28 131 8 8 3
B4GALT1 B4GALT1 P15291 Beta-1,4-galactosyltransferase 1 chr9 Not Cancer Driver No 1 hippie 38 129 13 13 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 Not Cancer Driver No 1 hippie 108 677 75 75 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 Compendium Yes 1 hippie 82 482 57 57 0
BTNL9 BTNL9 Q6UXG8 Butyrophilin-like protein 9 chr5 Not Cancer Driver No 1 hippie, biogrid 69 87 4 4 0
C18orf25 C18orf25 Q96B23 Uncharacterized protein C18orf25 chr18 Not Cancer Driver No 1 intact, hippie 30 393 27 27 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 Not Cancer Driver No 1 hippie, biogrid 23 119 18 18 0
CCNL1 CCNL1 Q9UK58 Cyclin-L1 chr3 Not Cancer Driver No 2 hippie, biogrid 58 281 38 38 0
CCNL2 CCNL2 Q96S94 Cyclin-L2 chr1 Not Cancer Driver No 3 hippie, biogrid 77 251 33 33 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 Not Cancer Driver No 2 hippie, biogrid 63 46 3 3 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 Not Cancer Driver No 1 hippie, biogrid 71 95 12 12 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 Not Cancer Driver No 2 hippie, biogrid 51 92 2 2 0
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 Not Cancer Driver No 2 hippie, biogrid 66 5 1 1 0
CCT6B CCT6B Q92526 T-complex protein 1 subunit zeta-2 chr17 Not Cancer Driver No 2 hippie, biogrid 90 1 0 0 0
CDC37 CDC37 Q16543 Hsp90 co-chaperone Cdc37 chr19 Not Cancer Driver No 4 intact, hippie, biogrid 52 214 31 31 0
CDK11A CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 Not Cancer Driver No 1 hippie 66 485 44 44 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 Not Cancer Driver No 1 hippie, biogrid 74 501 35 35 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 Census, Compendium Yes 1 hippie 166 83 88 88 36
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 Not Cancer Driver No 1 hippie 50 173 7 7 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 intact, hippie 335 157 130 130 13
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 Not Cancer Driver No 1 hippie 284 1017 160 160 3
COIL COIL P38432 Coilin chr17 Not Cancer Driver No 1 hippie, biogrid 61 385 42 42 0
CRNN CRNN Q9UBG3 Cornulin chr1 Not Cancer Driver No 1 hippie, biogrid 109 421 95 95 1
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 Not Cancer Driver No 3 intact, hippie, biogrid 71 75 8 8 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 Not Cancer Driver No 3 intact, hippie, biogrid 43 13 1 1 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 Not Cancer Driver No 2 hippie, biogrid 20 19 0 0 4
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 Not Cancer Driver No 1 hippie, biogrid 164 385 48 48 0
D2HGDH D2HGDH Q8N465 D-2-hydroxyglutarate dehydrogenase, mitochondrial chr2 Not Cancer Driver No 1 hippie, biogrid 61 46 1 1 0
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 Census, Compendium Yes 1 hippie, biogrid 45 70 5 5 2
DDX23 DDX23 Q9BUQ8 Probable ATP-dependent RNA helicase DDX23 chr12 Not Cancer Driver No 1 hippie, biogrid 121 426 71 71 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 Not Cancer Driver No 1 hippie 118 61 10 10 2
DHX40 DHX40 Q8IX18 Probable ATP-dependent RNA helicase DHX40 chr17 Not Cancer Driver No 1 hippie, biogrid 90 166 24 24 0
DHX8 DHX8 Q14562 ATP-dependent RNA helicase DHX8 chr17 Not Cancer Driver No 1 hippie, biogrid 138 490 72 72 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 Not Cancer Driver No 1 hippie, biogrid 67 179 30 30 5
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 Not Cancer Driver No 1 hippie 104 284 33 33 0
EEF1AKMT3 EEF1AKMT3 Q96AZ1 EEF1A lysine methyltransferase 3 chr12 Not Cancer Driver No 1 hippie 23 33 1 1 0
EID3 EID3 Q8N140 EP300-interacting inhibitor of differentiation 3 chr12 Not Cancer Driver No 1 hippie, biogrid 40 55 6 6 0
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 Not Cancer Driver No 1 hippie 29 125 8 8 1
EPS15L1_ENST00000248070 EPS15L1 Q9UBC2 Epidermal growth factor receptor substrate 15-like 1 chr19 Not Cancer Driver No 1 hippie 109 603 76 76 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 Census, Compendium Yes 1 intact, hippie 121 195 27 27 2
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 Census, Compendium Yes 1 hippie 322 230 38 38 0
FKBP5 FKBP5 Q13451 Peptidyl-prolyl cis-trans isomerase FKBP5 chr6 Not Cancer Driver No 3 intact, hippie, biogrid 70 150 20 20 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 Not Cancer Driver No 1 hippie 79 548 64 64 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 Not Cancer Driver No 1 hippie 10 39 5 5 0
GC_ENST00000273951 GC P02774 Vitamin D-binding protein chr4 Not Cancer Driver No 1 hippie, biogrid 93 13 3 3 0
HKR1 ZNF875 P10072 Zinc finger protein 875 chr19 Not Cancer Driver No 1 intact, hippie 105 191 26 26 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 3 intact, hippie, biogrid 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 3 intact, hippie, biogrid 100 254 43 43 0
HSPB8 HSPB8 Q9UJY1 Heat shock protein beta-8 chr12 Not Cancer Driver No 1 hippie, biogrid 40 130 31 31 5
HTRA4 HTRA4 P83105 Serine protease HTRA4 chr8 Not Cancer Driver No 1 hippie 57 15 0 0 0
ITIH2 ITIH2 P19823 Inter-alpha-trypsin inhibitor heavy chain H2 chr10 Not Cancer Driver No 1 hippie, biogrid 204 110 24 24 0
IVNS1ABP IVNS1ABP Q9Y6Y0 Influenza virus NS1A-binding protein chr1 Not Cancer Driver No 1 hippie 85 90 12 12 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 Not Cancer Driver No 1 hippie 61 277 50 50 0
KPNA2_ENST00000330459 KPNA2 P52292 Importin subunit alpha-1 chr17 Not Cancer Driver No 1 intact, hippie 74 129 18 18 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 Not Cancer Driver No 1 hippie 92 94 11 11 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 Not Cancer Driver No 1 hippie 58 350 44 44 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 Not Cancer Driver No 1 hippie, biogrid 74 611 69 69 0
LRRC29 LRRC29 Q8WV35 Leucine-rich repeat-containing protein 29 chr16 Not Cancer Driver No 1 hippie, biogrid 20 47 2 2 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 Not Cancer Driver No 2 intact, hippie 104 275 38 38 1
MCM4 MCM4 P33991 DNA replication licensing factor MCM4 chr8 Not Cancer Driver No 2 intact, hippie 121 215 35 35 0
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 Not Cancer Driver No 2 intact, hippie 101 122 13 13 0
MED4 MED4 Q9NPJ6 Mediator of RNA polymerase II transcription subunit 4 chr13 Not Cancer Driver No 1 hippie 29 161 17 17 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 hippie 85 569 68 68 0
NOLC1_ENST00000605788 NOLC1 Q14978 Nucleolar and coiled-body phosphoprotein 1 chr10 Not Cancer Driver No 1 hippie, biogrid 74 662 69 69 0
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 Not Cancer Driver No 1 intact, hippie 47 156 14 14 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 Not Cancer Driver No 1 hippie 10 82 10 10 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 Not Cancer Driver No 1 hippie 57 299 30 30 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 hippie, biogrid 119 320 34 34 0
PDHA1_ENST00000422285 PDHA1 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial chrX Not Cancer Driver No 1 hippie, biogrid 70 43 6 6 20
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 Not Cancer Driver No 1 hippie, biogrid 134 610 82 82 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 Not Cancer Driver No 1 hippie 17 115 12 12 0
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 Not Cancer Driver No 1 hippie 136 687 128 128 0
PNN PNN Q9H307 Pinin chr14 Not Cancer Driver No 1 hippie, biogrid 94 700 90 90 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
PRPF40A PRPF40A O75400 Pre-mRNA-processing factor 40 homolog A chr2 Not Cancer Driver No 1 hippie 83 694 57 57 0
PSMD1 PSMD1 Q99460 26S proteasome non-ATPase regulatory subunit 1 chr2 Not Cancer Driver No 1 intact, hippie 110 201 19 19 0
RBM25 RBM25 P49756 RNA-binding protein 25 chr14 Not Cancer Driver No 1 intact, hippie 124 549 88 88 0
RNPS1_ENST00000301730 RNPS1 Q15287 RNA-binding protein with serine-rich domain 1 chr16 Not Cancer Driver No 2 hippie, biogrid 30 305 30 30 0
RPL31_ENST00000264258 RPL31 P62899 60S ribosomal protein L31 chr2 Not Cancer Driver No 1 hippie, biogrid 19 69 14 14 0
RPS24_ENST00000613865 RPS24 P62847 40S ribosomal protein S24 chr10 Not Cancer Driver No 1 hippie, biogrid 13 88 10 10 0
S100A7A_ENST00000329256 S100A7A Q86SG5 Protein S100-A7A chr1 Not Cancer Driver No 1 hippie, biogrid 31 20 12 12 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 Census Yes 1 hippie, biogrid 39 28 14 14 0
SAP30BP SAP30BP Q9UHR5 SAP30-binding protein chr17 Not Cancer Driver No 2 hippie, biogrid 25 233 19 19 0
SENP3_ENST00000429205 SENP3 Q9H4L4 Sentrin-specific protease 3 chr17 Not Cancer Driver No 1 hippie, biogrid 53 288 30 30 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 Not Cancer Driver No 1 hippie, biogrid 120 48 18 18 0
SKIV2L SKIV2L Q15477 Helicase SKI2W chr6 Not Cancer Driver No 1 intact, hippie 140 390 54 54 1
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 Not Cancer Driver No 1 hippie 134 664 82 82 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 Census Yes 1 intact, hippie 39 312 39 39 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 Not Cancer Driver No 1 intact, hippie 63 332 44 44 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 Not Cancer Driver No 1 hippie 128 841 81 81 0
SPRR3 SPRR3 Q9UBC9 Small proline-rich protein 3 chr1 Not Cancer Driver No 1 hippie, biogrid 57 169 57 57 0
SRRT SRRT Q9BXP5 Serrate RNA effector molecule homolog chr7 Not Cancer Driver No 1 intact, hippie, biogrid 146 595 108 108 0
SRSF7 SRSF7 Q16629 Serine/arginine-rich splicing factor 7 chr2 Not Cancer Driver No 1 hippie 40 175 26 26 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUPT16H SUPT16H Q9Y5B9 FACT complex subunit SPT16 chr14 Not Cancer Driver No 1 hippie, biogrid 147 301 44 44 0
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 Not Cancer Driver No 1 hippie, biogrid 66 69 9 9 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 Not Cancer Driver No 1 hippie 109 141 24 24 0
UHRF2 UHRF2 Q96PU4 E3 ubiquitin-protein ligase UHRF2 chr9 Not Cancer Driver No 1 hippie 88 253 22 22 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 Not Cancer Driver No 1 hippie 136 259 39 39 0
WDR47_ENST00000369962 WDR47 O94967 WD repeat-containing protein 47 chr1 Not Cancer Driver No 1 hippie, biogrid 113 317 35 35 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 Not Cancer Driver No 1 intact, hippie, biogrid 166 105 13 13 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 Not Cancer Driver No 1 hippie 66 140 12 12 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 Census Yes 1 intact, hippie 32 41 3 3 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 Not Cancer Driver No 1 hippie, biogrid 139 929 134 134 0
ZFP14 ZFP14 Q9HCL3 Zinc finger protein 14 homolog chr19 Not Cancer Driver No 1 intact, hippie 88 52 10 10 0
ZG16B ZG16B Q96DA0 Zymogen granule protein 16 homolog B chr16 Not Cancer Driver No 1 hippie, biogrid 28 36 2 2 0
ZNF267 ZNF267 Q14586 Zinc finger protein 267 chr16 Not Cancer Driver No 1 intact, hippie 134 81 18 18 0
ZNF330 ZNF330 Q9Y3S2 Zinc finger protein 330 chr4 Not Cancer Driver No 1 hippie, biogrid 44 127 19 19 0
ZNF33A_ENST00000458705 ZNF33A Q06730 Zinc finger protein 33A chr10 Not Cancer Driver No 1 intact, hippie 150 142 21 21 0
ZNF460 ZNF460 Q14592 Zinc finger protein 460 chr19 Not Cancer Driver No 1 hippie 83 131 16 16 0
ZNF510 ZNF510 Q9Y2H8 Zinc finger protein 510 chr9 Not Cancer Driver No 1 intact, hippie 73 272 35 35 0