Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AARSD1 | AARSD1 | Q9BTE6 | Alanyl-tRNA editing protein Aarsd1 | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 40 | 157 | 20 | 20 | 0 |
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | Census, Compendium | Yes | 1 | hippie | 139 | 604 | 73 | 73 | 2 |
AGA | AGA | P20933 | N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | chr4 | Not Cancer Driver | No | 1 | hippie | 46 | 78 | 11 | 11 | 12 |
ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 104 | 146 | 26 | 26 | 0 |
APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | Not Cancer Driver | No | 2 | hippie, biogrid | 34 | 103 | 14 | 14 | 0 |
ASF1A | ASF1A | Q9Y294 | Histone chaperone ASF1A | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 18 | 69 | 2 | 2 | 0 |
ASH2L | ASH2L | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 95 | 293 | 39 | 39 | 0 |
ASXL1_ENST00000613218 | ASXL1 | Q8IXJ9 | Polycomb group protein ASXL1 | chr20 | Census, Compendium | Yes | 1 | hippie | 205 | 1300 | 174 | 174 | 0 |
ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | Census, Compendium | Yes | 1 | hippie | 469 | 225 | 39 | 39 | 41 |
ATR | ATR | Q13535 | Serine/threonine-protein kinase ATR | chr3 | Census, Compendium | Yes | 1 | hippie | 338 | 106 | 14 | 14 | 1 |
AURKB_ENST00000585124 | AURKB | Q96GD4 | Aurora kinase B | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 63 | 8 | 8 | 0 |
BABAM2_ENST00000342045 | BABAM2 | Q9NXR7 | BRISC and BRCA1-A complex member 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 52 | 0 | 0 | 0 | 0 |
BACH1_ENST00000286800 | BACH1 | O14867 | Transcription regulator protein BACH1 | chr21 | Not Cancer Driver | No | 1 | hippie | 105 | 328 | 39 | 39 | 0 |
BAG4 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 55 | 402 | 49 | 49 | 0 |
BARD1 | BARD1 | Q99728 | BRCA1-associated RING domain protein 1 | chr2 | Census | Yes | 1 | hippie | 96 | 384 | 49 | 49 | 0 |
BCCIP_ENST00000278100 | BCCIP | Q9P287 | BRCA2 and CDKN1A-interacting protein | chr10 | Not Cancer Driver | No | 1 | hippie | 35 | 99 | 16 | 16 | 0 |
BNC2 | BNC2 | Q6ZN30 | Zinc finger protein basonuclin-2 | chr9 | Not Cancer Driver | No | 1 | hippie | 242 | 682 | 150 | 150 | 1 |
BORCS8 | BORCS8 | Q96FH0 | BLOC-1-related complex subunit 8 | chr19 | Not Cancer Driver | No | 1 | hippie | 2 | 56 | 0 | 0 | 0 |
BPIFB4 | BPIFB4 | P59827 | BPI fold-containing family B member 4 | chr20 | Not Cancer Driver | No | 1 | hippie | 137 | 74 | 15 | 15 | 0 |
BRCA1_ENST00000357654 | BRCA1 | P38398 | Breast cancer type 1 susceptibility protein | chr17 | Census, Compendium | Yes | 4 | intact, hippie | 224 | 1458 | 174 | 174 | 35 |
BRCA2_ENST00000544455 | BRCA2 | P51587 | Breast cancer type 2 susceptibility protein | chr13 | Census, Compendium | Yes | 2 | intact, hippie | 457 | 1542 | 225 | 225 | 46 |
BRCC3 | BRCC3 | P46736 | Lys-63-specific deubiquitinase BRCC36 | chrX | Not Cancer Driver | No | 1 | hippie | 39 | 74 | 7 | 7 | 0 |
BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | Census | Yes | 1 | hippie | 174 | 397 | 59 | 59 | 6 |
BUB1B | BUB1B | O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | chr15 | Census | Yes | 1 | hippie | 96 | 480 | 35 | 35 | 7 |
C6orf141 | C6orf141 | Q5SZD1 | Uncharacterized protein C6orf141 | chr6 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 12 | 226 | 9 | 9 | 0 |
CABLES2 | CABLES2 | Q9BTV7 | CDK5 and ABL1 enzyme substrate 2 | chr20 | Not Cancer Driver | No | 1 | hippie | 38 | 250 | 11 | 11 | 0 |
CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 53 | 126 | 7 | 7 | 1 |
CAT | CAT | P04040 | Catalase | chr11 | Not Cancer Driver | No | 1 | hippie | 70 | 176 | 18 | 18 | 0 |
CCDC24 | CCDC24 | Q8N4L8 | Coiled-coil domain-containing protein 24 | chr1 | Not Cancer Driver | No | 1 | hippie | 36 | 138 | 23 | 23 | 0 |
CCDC96 | CCDC96 | Q2M329 | Coiled-coil domain-containing protein 96 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 74 | 308 | 41 | 41 | 0 |
CCNA1 | CCNA1 | P78396 | Cyclin-A1 | chr13 | Not Cancer Driver | No | 1 | hippie | 112 | 82 | 21 | 21 | 0 |
CCNA2_ENST00000618014 | CCNA2 | P20248 | Cyclin-A2 | chr4 | Not Cancer Driver | No | 1 | hippie | 45 | 186 | 19 | 19 | 0 |
CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | Not Cancer Driver | No | 1 | hippie | 49 | 145 | 14 | 14 | 0 |
CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | Census, Compendium | Yes | 1 | hippie | 55 | 31 | 25 | 25 | 0 |
CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | Census | Yes | 1 | hippie | 63 | 142 | 26 | 26 | 0 |
CCT8L2 | CCT8L2 | Q96SF2 | T-complex protein 1 subunit theta-like 2 | chr22 | Not Cancer Driver | No | 1 | hippie, biogrid | 216 | 104 | 46 | 46 | 0 |
CDC45_ENST00000407835 | CDC45 | O75419 | Cell division control protein 45 homolog | chr22 | Not Cancer Driver | No | 1 | intact, hippie | 73 | 66 | 16 | 16 | 5 |
CDK2 | CDK2 | P24941 | Cyclin-dependent kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 24 | 0 | 0 | 0 | 0 |
CELF3 | CELF3 | Q5SZQ8 | CUGBP Elav-like family member 3 | chr1 | Not Cancer Driver | No | 1 | hippie | 82 | 201 | 33 | 33 | 0 |
CEP135 | CEP135 | Q66GS9 | Centrosomal protein of 135 kDa | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 127 | 690 | 72 | 72 | 0 |
CFAP299_ENST00000358105 | CFAP299 | Q6V702 | Cilia- and flagella-associated protein 299 | chr4 | Not Cancer Driver | No | 1 | hippie | 51 | 29 | 7 | 7 | 0 |
CFAP52 | CFAP52 | Q8N1V2 | Cilia- and flagella-associated protein 52 | chr17 | Not Cancer Driver | No | 1 | hippie | 107 | 4 | 0 | 0 | 0 |
CFH | CFH | P08603 | Complement factor H | chr1 | Not Cancer Driver | No | 1 | hippie | 355 | 89 | 28 | 28 | 42 |
CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | Not Cancer Driver | No | 1 | hippie | 58 | 86 | 16 | 16 | 0 |
CHEK2_ENST00000405598 | CHEK2 | O96017 | Serine/threonine-protein kinase Chk2 | chr22 | Census, Compendium | Yes | 1 | hippie | 335 | 157 | 130 | 130 | 13 |
CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | Not Cancer Driver | No | 1 | hippie | 25 | 201 | 22 | 22 | 2 |
CLHC1_ENST00000407122 | CLHC1 | Q8NHS4 | Clathrin heavy chain linker domain-containing protein 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 68 | 15 | 0 | 0 | 0 |
CNKSR1 | CNKSR1 | Q969H4 | Connector enhancer of kinase suppressor of ras 1 | chr1 | Not Cancer Driver | No | 2 | hippie, biogrid | 118 | 405 | 68 | 68 | 0 |
COL11A1 | COL11A1 | P12107 | Collagen alpha-1(XI) chain | chr1 | Not Cancer Driver | No | 1 | hippie | 749 | 1436 | 617 | 617 | 8 |
CRYAA | CRYAA | P02489 | Alpha-crystallin A chain | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 34 | 42 | 11 | 11 | 10 |
CRYL1 | CRYL1 | Q9Y2S2 | Lambda-crystallin homolog | chr13 | Not Cancer Driver | No | 1 | hippie, biogrid | 36 | 29 | 3 | 3 | 0 |
CT55 | CT55 | Q8WUE5 | Cancer/testis antigen 55 | chrX | Not Cancer Driver | No | 1 | hippie | 42 | 40 | 3 | 3 | 0 |
CWF19L2 | CWF19L2 | Q2TBE0 | CWF19-like protein 2 | chr11 | Not Cancer Driver | No | 1 | hippie | 119 | 615 | 83 | 83 | 0 |
DCST2 | DCST2 | Q5T1A1 | DC-STAMP domain-containing protein 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 110 | 130 | 15 | 15 | 0 |
DDX3Y_ENST00000336079 | DDX3Y | O15523 | ATP-dependent RNA helicase DDX3Y | chrY | Not Cancer Driver | No | 1 | hippie | 31 | 289 | 18 | 18 | 0 |
DGKH | DGKH | Q86XP1 | Diacylglycerol kinase eta | chr13 | Not Cancer Driver | No | 1 | hippie | 138 | 326 | 43 | 43 | 0 |
DMC1 | DMC1 | Q14565 | Meiotic recombination protein DMC1/LIM15 homolog | chr22 | Not Cancer Driver | No | 2 | intact, hippie | 39 | 49 | 5 | 5 | 0 |
DNAH9 | DNAH9 | Q9NYC9 | Dynein axonemal heavy chain 9 | chr17 | Not Cancer Driver | No | 1 | hippie | 1009 | 325 | 64 | 64 | 4 |
DPPA3 | DPPA3 | Q6W0C5 | Developmental pluripotency-associated protein 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 58 | 105 | 43 | 43 | 0 |
DSN1 | DSN1 | Q9H410 | Kinetochore-associated protein DSN1 homolog | chr20 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 45 | 191 | 28 | 28 | 0 |
DTNBP1 | DTNBP1 | Q96EV8 | Dysbindin | chr6 | Not Cancer Driver | No | 1 | hippie, biogrid | 49 | 210 | 25 | 25 | 0 |
DUSP16 | DUSP16 | Q9BY84 | Dual specificity protein phosphatase 16 | chr12 | Compendium | Yes | 1 | hippie, biogrid | 70 | 273 | 34 | 34 | 0 |
DYDC1_ENST00000421924 | DYDC1 | Q8WWB3 | DPY30 domain-containing protein 1 | chr10 | Not Cancer Driver | No | 1 | hippie | 29 | 94 | 17 | 17 | 0 |
DYNC1H1 | DYNC1H1 | Q14204 | Cytoplasmic dynein 1 heavy chain 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 505 | 495 | 62 | 62 | 21 |
DYNC1LI1 | DYNC1LI1 | Q9Y6G9 | Cytoplasmic dynein 1 light intermediate chain 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 46 | 208 | 20 | 20 | 0 |
DYNC1LI2 | DYNC1LI2 | O43237 | Cytoplasmic dynein 1 light intermediate chain 2 | chr16 | Not Cancer Driver | No | 1 | hippie | 43 | 211 | 14 | 14 | 0 |
EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | Not Cancer Driver | No | 1 | hippie | 33 | 13 | 0 | 0 | 0 |
EIF2B4_ENST00000347454 | EIF2B4 | Q9UI10 | Translation initiation factor eIF-2B subunit delta | chr2 | Not Cancer Driver | No | 1 | hippie | 57 | 212 | 29 | 29 | 7 |
EMSY_ENST00000529032 | EMSY | Q7Z589 | BRCA2-interacting transcriptional repressor EMSY | chr11 | Not Cancer Driver | No | 1 | hippie | 166 | 1151 | 147 | 147 | 0 |
ERCC5 | ERCC5 | P28715 | DNA excision repair protein ERCC-5 | chr13 | Census | Yes | 1 | hippie | 175 | 816 | 121 | 121 | 6 |
ETAA1 | ETAA1 | Q9NY74 | Ewing's tumor-associated antigen 1 | chr2 | Not Cancer Driver | No | 1 | hippie | 101 | 735 | 75 | 75 | 0 |
F8 | F8 | P00451 | Coagulation factor VIII | chrX | Not Cancer Driver | No | 1 | hippie | 414 | 931 | 174 | 174 | 472 |
FAM160A2_ENST00000449352 | FHIP1B | Q8N612 | FHF complex subunit HOOK interacting protein 1B | chr11 | Not Cancer Driver | No | 1 | intact | 129 | 415 | 54 | 54 | 0 |
FANCD2_ENST00000383807 | FANCD2 | Q9BXW9 | Fanconi anemia group D2 protein | chr3 | Census, Compendium | Yes | 2 | intact, hippie | 176 | 181 | 14 | 14 | 3 |
FANCE | FANCE | Q9HB96 | Fanconi anemia group E protein | chr6 | Census | Yes | 1 | hippie | 47 | 199 | 22 | 22 | 0 |
FANCG | FANCG | O15287 | Fanconi anemia group G protein | chr9 | Census | Yes | 1 | hippie | 64 | 48 | 3 | 3 | 1 |
FANCI | FANCI | Q9NVI1 | Fanconi anemia group I protein | chr15 | Not Cancer Driver | No | 1 | hippie | 161 | 129 | 20 | 20 | 2 |
FBXL13_ENST00000436908 | FBXL13 | Q8NEE6 | Dynein regulatory complex subunit 6 | chr7 | Not Cancer Driver | No | 1 | hippie | 103 | 41 | 5 | 5 | 0 |
FIG4 | FIG4 | Q92562 | Polyphosphoinositide phosphatase | chr6 | Not Cancer Driver | No | 1 | hippie | 114 | 177 | 26 | 26 | 7 |
FLNA | FLNA | P21333 | Filamin-A | chrX | Census | Yes | 1 | hippie | 416 | 1456 | 214 | 214 | 28 |
FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | Not Cancer Driver | No | 1 | hippie | 92 | 70 | 13 | 13 | 0 |
FZD8 | FZD8 | Q9H461 | Frizzled-8 | chr10 | Not Cancer Driver | No | 1 | hippie | 72 | 146 | 3 | 3 | 0 |
GOLGA6L2 | GOLGA6L2 | Q8N9W4 | Golgin subfamily A member 6-like protein 2 | chr15 | Not Cancer Driver | No | 1 | hippie | 57 | 830 | 50 | 50 | 0 |
GRB2_ENST00000392564 | GRB2 | P62993 | Growth factor receptor-bound protein 2 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 28 | 10 | 1 | 1 | 0 |
GREB1L | GREB1L | Q9C091 | GREB1-like protein | chr18 | Not Cancer Driver | No | 1 | hippie | 87 | 480 | 22 | 22 | 25 |
HMG20B | HMG20B | Q9P0W2 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related | chr19 | Not Cancer Driver | No | 1 | hippie | 27 | 237 | 18 | 18 | 0 |
HNRNPC_ENST00000420743 | HNRNPC | P07910 | Heterogeneous nuclear ribonucleoproteins C1/C2 | chr14 | Not Cancer Driver | No | 1 | hippie | 42 | 227 | 35 | 35 | 0 |
HSF2BP | HSF2BP | O75031 | Heat shock factor 2-binding protein | chr21 | Not Cancer Driver | No | 1 | hippie, biogrid | 52 | 23 | 3 | 3 | 1 |
HSP90B1 | HSP90B1 | P14625 | Endoplasmin | chr12 | Not Cancer Driver | No | 1 | hippie | 94 | 268 | 35 | 35 | 0 |
HSPB8 | HSPB8 | Q9UJY1 | Heat shock protein beta-8 | chr12 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 40 | 130 | 31 | 31 | 5 |
IER2_ENST00000587885 | IER2 | Q9BTL4 | Immediate early response gene 2 protein | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 16 | 178 | 13 | 13 | 0 |
KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | Not Cancer Driver | No | 1 | hippie | 107 | 266 | 27 | 27 | 0 |
KATNAL2_ENST00000356157 | KATNAL2 | Q8IYT4 | Katanin p60 ATPase-containing subunit A-like 2 | chr18 | Not Cancer Driver | No | 1 | hippie | 84 | 142 | 30 | 30 | 0 |
KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | Census, Compendium | Yes | 1 | hippie | 237 | 57 | 12 | 12 | 0 |
KIF4A | KIF4A | O95239 | Chromosome-associated kinesin KIF4A | chrX | Not Cancer Driver | No | 1 | hippie | 188 | 674 | 116 | 116 | 0 |
KLHL40 | KLHL40 | Q2TBA0 | Kelch-like protein 40 | chr3 | Not Cancer Driver | No | 1 | hippie, biogrid | 108 | 44 | 8 | 8 | 13 |
KRT2 | KRT2 | P35908 | Keratin, type II cytoskeletal 2 epidermal | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 122 | 335 | 59 | 59 | 15 |
KRT38 | KRT38 | O76015 | Keratin, type I cuticular Ha8 | chr17 | Not Cancer Driver | No | 1 | hippie, biogrid | 89 | 52 | 15 | 15 | 0 |
KRT78 | KRT78 | Q8N1N4 | Keratin, type II cytoskeletal 78 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 96 | 122 | 27 | 27 | 0 |
L3MBTL1 | L3MBTL1 | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | chr20 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 116 | 447 | 40 | 40 | 0 |
LIMD1 | LIMD1 | Q9UGP4 | LIM domain-containing protein 1 | chr3 | Not Cancer Driver | No | 1 | hippie | 58 | 428 | 36 | 36 | 0 |
LMNA | LMNA | P02545 | Prelamin-A/C | chr1 | Census | Yes | 1 | hippie | 68 | 544 | 49 | 49 | 131 |
LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | Not Cancer Driver | No | 1 | hippie | 519 | 90 | 17 | 17 | 23 |
LZTS2 | LZTS2 | Q9BRK4 | Leucine zipper putative tumor suppressor 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 78 | 508 | 66 | 66 | 0 |
MAGED1_ENST00000326587 | MAGED1 | Q9Y5V3 | Melanoma-associated antigen D1 | chrX | Not Cancer Driver | No | 1 | hippie | 131 | 457 | 71 | 71 | 0 |
MAPK6 | MAPK6 | Q16659 | Mitogen-activated protein kinase 6 | chr15 | Not Cancer Driver | No | 1 | hippie | 79 | 165 | 20 | 20 | 0 |
MCPH1 | MCPH1 | Q8NEM0 | Microcephalin | chr8 | Not Cancer Driver | No | 1 | hippie | 110 | 446 | 62 | 62 | 1 |
MDC1 | MDC1 | Q14676 | Mediator of DNA damage checkpoint protein 1 | chr6 | Not Cancer Driver | No | 1 | hippie | 249 | 1829 | 223 | 223 | 0 |
MDFIC_ENST00000393486 | MDFIC | Q9P1T7 | MyoD family inhibitor domain-containing protein | chr7 | Not Cancer Driver | No | 1 | hippie | 35 | 143 | 23 | 23 | 0 |
MFSD13A | MFSD13A | Q14CX5 | Transmembrane protein 180 | chr10 | Not Cancer Driver | No | 1 | hippie | 40 | 12 | 0 | 0 | 0 |
MGMT | MGMT | B4DEE8 | Methylated-DNA--protein-cysteine methyltransferase | chr10 | Census | Yes | 1 | hippie | 43 | 40 | 15 | 15 | 0 |
MIER2 | MIER2 | Q8N344 | Mesoderm induction early response protein 2 | chr19 | Not Cancer Driver | No | 1 | hippie, biogrid | 72 | 365 | 45 | 45 | 0 |
MLF1_ENST00000355893 | MLF1 | P58340 | Myeloid leukemia factor 1 | chr3 | Census | Yes | 3 | hippie, biogrid | 40 | 243 | 37 | 37 | 0 |
MMP10 | MMP10 | P09238 | Stromelysin-2 | chr11 | Not Cancer Driver | No | 1 | hippie | 88 | 38 | 9 | 9 | 0 |
MORF4L1 | MORF4L1 | Q9UBU8 | Mortality factor 4-like protein 1 | chr15 | Not Cancer Driver | No | 3 | hippie, biogrid | 43 | 163 | 17 | 17 | 0 |
MORF4L2_ENST00000433176 | MORF4L2 | Q15014 | Mortality factor 4-like protein 2 | chrX | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 44 | 136 | 21 | 21 | 0 |
MTA2 | MTA2 | O94776 | Metastasis-associated protein MTA2 | chr11 | Not Cancer Driver | No | 1 | intact, hippie | 78 | 283 | 32 | 32 | 0 |
MTMR6 | MTMR6 | Q9Y217 | Myotubularin-related protein 6 | chr13 | Not Cancer Driver | No | 1 | hippie | 87 | 68 | 16 | 16 | 0 |
MYH14_ENST00000596571 | MYH14 | Q7Z406 | Myosin-14 | chr19 | Not Cancer Driver | No | 1 | hippie | 275 | 1215 | 169 | 169 | 5 |
NAA11 | NAA11 | Q9BSU3 | N-alpha-acetyltransferase 11 | chr4 | Not Cancer Driver | No | 1 | hippie, biogrid | 64 | 123 | 31 | 31 | 0 |
NCAPH2_ENST00000420993 | NCAPH2 | Q6IBW4 | Condensin-2 complex subunit H2 | chr22 | Not Cancer Driver | No | 2 | hippie, biogrid | 67 | 335 | 39 | 39 | 0 |
NCKAP5 | NCKAP5 | O14513 | Nck-associated protein 5 | chr2 | Not Cancer Driver | No | 1 | hippie | 450 | 1677 | 408 | 408 | 0 |
NCL | NCL | P19338 | Nucleolin | chr2 | Not Cancer Driver | No | 1 | intact, hippie | 85 | 569 | 68 | 68 | 0 |
NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | Not Cancer Driver | No | 1 | hippie | 150 | 711 | 79 | 79 | 0 |
NEURL4 | NEURL4 | Q96JN8 | Neuralized-like protein 4 | chr17 | Not Cancer Driver | No | 1 | intact, hippie | 217 | 751 | 119 | 119 | 0 |
NIN | NIN | Q8N4C6 | Ninein | chr14 | Census, Compendium | Yes | 1 | hippie | 239 | 1392 | 164 | 164 | 2 |
NINL | NINL | Q9Y2I6 | Ninein-like protein | chr20 | Not Cancer Driver | No | 1 | hippie | 230 | 881 | 150 | 150 | 0 |
NPM1 | NPM1 | P06748 | Nucleophosmin | chr5 | Census, Compendium | Yes | 1 | hippie | 29 | 249 | 22 | 22 | 0 |
NPR2 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | Not Cancer Driver | No | 1 | biogrid | 144 | 89 | 18 | 18 | 20 |
NPY4R_ENST00000612632 | NPY4R | P50391 | Neuropeptide Y receptor type 4 | chr10 | Not Cancer Driver | No | 1 | biogrid | 110 | 5 | 2 | 2 | 0 |
NSL1 | NSL1 | Q96IY1 | Kinetochore-associated protein NSL1 homolog | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 30 | 117 | 12 | 12 | 0 |
NSMCE4A | NSMCE4A | Q9NXX6 | Non-structural maintenance of chromosomes element 4 homolog A | chr10 | Not Cancer Driver | No | 3 | intact, hippie, biogrid | 17 | 200 | 5 | 5 | 0 |
OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | Not Cancer Driver | No | 1 | hippie | 107 | 58 | 27 | 27 | 0 |
PALB2 | PALB2 | Q86YC2 | Partner and localizer of BRCA2 | chr16 | Census | Yes | 13 | intact, hippie, biogrid | 124 | 769 | 77 | 77 | 1 |
PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | Not Cancer Driver | No | 1 | intact | 119 | 320 | 34 | 34 | 0 |
PCNA | PCNA | P12004 | Proliferating cell nuclear antigen | chr20 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 22 | 3 | 3 | 1 |
PDS5B | PDS5B | Q9NTI5 | Sister chromatid cohesion protein PDS5 homolog B | chr13 | Not Cancer Driver | No | 1 | hippie | 174 | 455 | 61 | 61 | 0 |
PKLR | PKLR | P30613 | Pyruvate kinase PKLR | chr1 | Not Cancer Driver | No | 1 | biogrid | 112 | 26 | 5 | 5 | 101 |
PLEC | PLEC | Q15149 | Plectin | chr8 | Not Cancer Driver | No | 1 | hippie | 677 | 2130 | 272 | 272 | 2 |
PLK1 | PLK1 | P53350 | Serine/threonine-protein kinase PLK1 | chr16 | Not Cancer Driver | No | 1 | hippie | 87 | 119 | 13 | 13 | 0 |
PMS1 | PMS1 | P54277 | PMS1 protein homolog 1 | chr2 | Census | Yes | 1 | hippie | 114 | 283 | 38 | 38 | 0 |
PMS2 | PMS2 | P54278 | Mismatch repair endonuclease PMS2 | chr7 | Census, Compendium | Yes | 1 | hippie | 117 | 331 | 44 | 44 | 9 |
POLH | POLH | Q9Y253 | DNA polymerase eta | chr6 | Not Cancer Driver | No | 1 | intact, hippie | 72 | 291 | 20 | 20 | 10 |
POLN_ENST00000382865 | POLN | Q7Z5Q5 | DNA polymerase nu | chr4 | Not Cancer Driver | No | 1 | hippie | 115 | 247 | 28 | 28 | 0 |
POLR1E | POLR1E | Q9GZS1 | DNA-directed RNA polymerase I subunit RPA49 | chr9 | Not Cancer Driver | No | 1 | hippie, biogrid | 39 | 85 | 6 | 6 | 0 |
POLR2A | POLR2A | P24928-2 | Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 | chr17 | Census | Yes | 1 | hippie | 56 | 230 | 20 | 20 | 0 |
PPA2 | PPA2 | Q9H2U2 | Inorganic pyrophosphatase 2, mitochondrial | chr4 | Not Cancer Driver | No | 1 | hippie | 49 | 71 | 9 | 9 | 9 |
PPM1E | PPM1E | Q8WY54 | Protein phosphatase 1E | chr17 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 114 | 384 | 53 | 53 | 0 |
PPP1R17 | PPP1R17 | O96001 | Protein phosphatase 1 regulatory subunit 17 | chr7 | Not Cancer Driver | No | 1 | hippie | 39 | 143 | 36 | 36 | 0 |
PPP2CA | PPP2CA | P67775 | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform | chr5 | Not Cancer Driver | No | 1 | hippie | 41 | 12 | 1 | 1 | 8 |
PRELID2 | PRELID2 | Q8N945 | PRELI domain-containing protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 20 | 3 | 0 | 0 | 0 |
PSMD3 | PSMD3 | O43242 | 26S proteasome non-ATPase regulatory subunit 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 69 | 152 | 19 | 19 | 0 |
PSMD6_ENST00000295901 | PSMD6 | Q15008 | 26S proteasome non-ATPase regulatory subunit 6 | chr3 | Not Cancer Driver | No | 1 | hippie | 33 | 40 | 3 | 3 | 0 |
PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | Not Cancer Driver | No | 1 | hippie, biogrid | 11 | 52 | 3 | 3 | 0 |
PTPA_ENST00000337738 | PTPA | Q15257 | Serine/threonine-protein phosphatase 2A activator | chr9 | Not Cancer Driver | No | 1 | hippie | 40 | 63 | 2 | 2 | 0 |
PYGM | PYGM | P11217 | Glycogen phosphorylase, muscle form | chr11 | Not Cancer Driver | No | 1 | hippie | 153 | 39 | 4 | 4 | 17 |
RABL2A_ENST00000393166 | RABL2A | Q9UBK7 | Rab-like protein 2A | chr2 | Not Cancer Driver | No | 2 | intact, hippie, biogrid | 23 | 44 | 5 | 5 | 0 |
RAD21 | RAD21 | O60216 | Double-strand-break repair protein rad21 homolog | chr8 | Census, Compendium | Yes | 1 | intact, hippie | 115 | 421 | 74 | 74 | 3 |
RAD23A | RAD23A | P54725 | UV excision repair protein RAD23 homolog A | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 50 | 283 | 41 | 41 | 0 |
RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | Not Cancer Driver | No | 1 | hippie | 157 | 730 | 84 | 84 | 0 |
RAD51C | RAD51C | O43502 | DNA repair protein RAD51 homolog 3 | chr17 | Not Cancer Driver | No | 1 | hippie | 47 | 18 | 2 | 2 | 6 |
RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | Not Cancer Driver | No | 17 | intact, hippie, biogrid | 42 | 47 | 5 | 5 | 3 |
RELCH | RELCH | Q9P260 | RAB11-binding protein RELCH | chr18 | Not Cancer Driver | No | 1 | hippie | 114 | 384 | 29 | 29 | 0 |
RFXANK_ENST00000407360 | RFXANK | O14593 | DNA-binding protein RFXANK | chr19 | Not Cancer Driver | No | 1 | intact, hippie, biogrid | 22 | 120 | 6 | 6 | 1 |
RNASEH2A | RNASEH2A | O75792 | Ribonuclease H2 subunit A | chr19 | Not Cancer Driver | No | 1 | hippie | 42 | 31 | 3 | 3 | 7 |
RNF168 | RNF168 | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | chr3 | Not Cancer Driver | No | 1 | hippie | 77 | 471 | 66 | 66 | 0 |
ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | Not Cancer Driver | No | 1 | hippie | 145 | 732 | 81 | 81 | 0 |
RPA1 | RPA1 | P27694 | Replication protein A 70 kDa DNA-binding subunit | chr17 | Not Cancer Driver | No | 1 | hippie | 51 | 98 | 6 | 6 | 0 |
RPA2_ENST00000373912 | RPA2 | P15927 | Replication protein A 32 kDa subunit | chr1 | Not Cancer Driver | No | 1 | hippie | 28 | 114 | 16 | 16 | 0 |
RUFY3_ENST00000226328 | RUFY3 | Q7L099 | Protein RUFY3 | chr4 | Not Cancer Driver | No | 1 | hippie | 75 | 204 | 29 | 29 | 0 |
SDF4 | SDF4 | Q9BRK5 | 45 kDa calcium-binding protein | chr1 | Not Cancer Driver | No | 1 | hippie, biogrid | 48 | 187 | 30 | 30 | 0 |
SEM1_ENST00000356686 | SEM1 | Q6ZVN7 | Putative protein SEM1, isoform 2 | chr7 | Not Cancer Driver | No | 1 | hippie | 2 | 52 | 1 | 1 | 0 |
SERPINH1_ENST00000358171 | SERPINH1 | P50454 | Serpin H1 | chr11 | Not Cancer Driver | No | 1 | hippie | 51 | 52 | 6 | 6 | 1 |
SHANK1 | SHANK1 | Q9Y566 | SH3 and multiple ankyrin repeat domains protein 1 | chr19 | Not Cancer Driver | No | 1 | hippie | 288 | 1659 | 186 | 186 | 0 |
SHLD2_ENST00000298784 | SHLD2 | Q86V20 | Shieldin complex subunit 2 | chr10 | Not Cancer Driver | No | 1 | hippie | 84 | 157 | 14 | 14 | 0 |
SKP2 | SKP2 | Q13309 | S-phase kinase-associated protein 2 | chr5 | Not Cancer Driver | No | 1 | hippie | 52 | 52 | 6 | 6 | 0 |
SLC16A14 | SLC16A14 | Q7RTX9 | Monocarboxylate transporter 14 | chr2 | Not Cancer Driver | No | 1 | hippie | 126 | 52 | 16 | 16 | 0 |
SLCO1B3_ENST00000381545 | SLCO1B3 | Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | chr12 | Not Cancer Driver | No | 1 | hippie | 208 | 35 | 8 | 8 | 0 |
SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | Census, Compendium | Yes | 1 | hippie | 79 | 137 | 12 | 12 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | Census, Compendium | Yes | 1 | hippie | 97 | 111 | 19 | 19 | 5 |
SMC3 | SMC3 | Q9UQE7 | Structural maintenance of chromosomes protein 3 | chr10 | Not Cancer Driver | No | 1 | intact, hippie | 149 | 605 | 70 | 70 | 0 |
SNX32 | SNX32 | Q86XE0 | Sorting nexin-32 | chr11 | Not Cancer Driver | No | 2 | hippie, biogrid | 64 | 86 | 10 | 10 | 0 |
SNX6 | SNX6 | Q9UNH7 | Sorting nexin-6 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 33 | 85 | 7 | 7 | 0 |
SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | Not Cancer Driver | No | 1 | hippie | 96 | 599 | 71 | 71 | 0 |
SPHK2 | SPHK2 | Q9NRA0 | Sphingosine kinase 2 | chr19 | Not Cancer Driver | No | 1 | biogrid | 82 | 293 | 39 | 39 | 0 |
STAT5A_ENST00000590949 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | Not Cancer Driver | No | 1 | hippie | 89 | 125 | 14 | 14 | 0 |
STRN4_ENST00000263280 | STRN4 | Q9NRL3 | Striatin-4 | chr19 | Not Cancer Driver | No | 1 | hippie | 84 | 407 | 40 | 40 | 0 |
SUPT3H_ENST00000371459 | SUPT3H | O75486 | Transcription initiation protein SPT3 homolog | chr6 | Not Cancer Driver | No | 1 | hippie | 49 | 49 | 4 | 4 | 0 |
SYCP3_ENST00000392924 | SYCP3 | Q8IZU3 | Synaptonemal complex protein 3 | chr12 | Not Cancer Driver | No | 1 | intact, hippie | 30 | 124 | 12 | 12 | 0 |
SYNE3 | SYNE3 | Q6ZMZ3 | Nesprin-3 | chr14 | Not Cancer Driver | No | 1 | hippie, biogrid | 143 | 236 | 42 | 42 | 0 |
TEP1 | TEP1 | Q99973 | Telomerase protein component 1 | chr14 | Not Cancer Driver | No | 1 | hippie | 332 | 396 | 67 | 67 | 0 |
TERF2IP | TERF2IP | Q9NYB0 | Telomeric repeat-binding factor 2-interacting protein 1 | chr16 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 310 | 16 | 16 | 0 |
TERT | TERT | O14746 | Telomerase reverse transcriptase | chr5 | Census | Yes | 1 | hippie | 110 | 212 | 16 | 16 | 31 |
TEX45 | TEX45 | Q8NA69 | Testis-expressed protein 45 | chr19 | Not Cancer Driver | No | 1 | intact, hippie | 41 | 415 | 30 | 30 | 0 |
TP53BP1_ENST00000263801 | TP53BP1 | Q12888 | TP53-binding protein 1 | chr15 | Not Cancer Driver | No | 1 | intact, hippie | 227 | 1632 | 190 | 190 | 0 |
TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | Census, Compendium | Yes | 2 | intact, hippie | 2891 | 282 | 1466 | 1466 | 83 |
TPSAB1 | TPSAB1 | Q15661 | Tryptase alpha/beta-1 | chr16 | Not Cancer Driver | No | 1 | biogrid | 40 | 28 | 6 | 6 | 0 |
TRIM29 | TRIM29 | Q14134 | Tripartite motif-containing protein 29 | chr11 | Not Cancer Driver | No | 1 | hippie | 121 | 351 | 72 | 72 | 0 |
TRIM52 | TRIM52 | Q96A61 | E3 ubiquitin-protein ligase TRIM52 | chr5 | Not Cancer Driver | No | 1 | hippie, biogrid | 23 | 147 | 13 | 13 | 0 |
TSGA10IP | TSGA10IP | Q3SY00 | Testis-specific protein 10-interacting protein | chr11 | Not Cancer Driver | No | 1 | hippie, biogrid | 79 | 552 | 79 | 79 | 0 |
TTF2 | TTF2 | Q9UNY4 | Transcription termination factor 2 | chr1 | Not Cancer Driver | No | 1 | hippie | 118 | 550 | 50 | 50 | 0 |
TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | Not Cancer Driver | No | 1 | biogrid | 148 | 213 | 29 | 29 | 0 |
UIMC1_ENST00000511320 | UIMC1 | Q96RL1 | BRCA1-A complex subunit RAP80 | chr5 | Not Cancer Driver | No | 1 | hippie | 64 | 609 | 51 | 51 | 0 |
UPP1_ENST00000395564 | UPP1 | Q16831 | Uridine phosphorylase 1 | chr7 | Not Cancer Driver | No | 1 | hippie, biogrid | 47 | 13 | 3 | 3 | 0 |
UQCC1 | UQCC1 | Q9NVA1 | Ubiquinol-cytochrome-c reductase complex assembly factor 1 | chr20 | Not Cancer Driver | No | 1 | hippie | 46 | 59 | 10 | 10 | 0 |
USP11 | USP11 | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | chrX | Not Cancer Driver | No | 2 | intact, hippie | 140 | 210 | 28 | 28 | 0 |
USP21_ENST00000289865 | USP21 | Q9UK80 | Ubiquitin carboxyl-terminal hydrolase 21 | chr1 | Not Cancer Driver | No | 1 | hippie | 95 | 230 | 47 | 47 | 0 |
UTP14C | UTP14C | Q5TAP6 | U3 small nucleolar RNA-associated protein 14 homolog C | chr13 | Not Cancer Driver | No | 1 | hippie | 84 | 657 | 72 | 72 | 0 |
VIRMA | VIRMA | Q69YN4 | Protein virilizer homolog | chr8 | Not Cancer Driver | No | 1 | hippie | 211 | 631 | 93 | 93 | 0 |
VPS28_ENST00000292510 | VPS28 | Q9UK41 | Vacuolar protein sorting-associated protein 28 homolog | chr8 | Not Cancer Driver | No | 1 | hippie, biogrid | 28 | 31 | 5 | 5 | 0 |
WTIP | WTIP | A6NIX2 | Wilms tumor protein 1-interacting protein | chr19 | Not Cancer Driver | No | 1 | hippie | 32 | 217 | 2 | 2 | 0 |
XPO1_ENST00000406957 | XPO1 | O14980 | Exportin-1 | chr2 | Census, Compendium | Yes | 1 | hippie | 140 | 33 | 9 | 9 | 0 |
XRCC3_ENST00000352127 | XRCC3 | O43542 | DNA repair protein XRCC3 | chr14 | Not Cancer Driver | No | 3 | intact, hippie | 24 | 35 | 2 | 2 | 1 |
ZNF503 | ZNF503 | Q96F45 | Zinc finger protein 503 | chr10 | Not Cancer Driver | No | 1 | hippie | 26 | 446 | 14 | 14 | 0 |
ZNF707_ENST00000358656 | ZNF707 | Q96C28 | Zinc finger protein 707 | chr8 | Not Cancer Driver | No | 1 | hippie | 53 | 138 | 21 | 21 | 0 |
ZYG11A | ZYG11A | Q6WRX3 | Protein zyg-11 homolog A | chr1 | Not Cancer Driver | No | 1 | hippie | 52 | 7 | 0 | 0 | 0 |
Identifier |
UniProt Gene |
UniProt Accession |
UniProt Name |
Chromosome |
Cancer Database |
Cancer Driver |
Number of independent pubication |
Interaction Database |
Number of missense mutations |
Number of disordered residues |
Number of mutations in disordered residues |
Number of mutations in disordered residues |
Number of omim mutations |
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