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BRCA2_ENST00000544455 ,BRCA2 ,P51587
  • Uniprot Accession= P51587
  • Ensembl Transcript= ENST00000544455.5
  • Uniprot Name= BRCA2
  • Name= Breast cancer type 2 susceptibility protein
  • Chromosome= chr13
  • Driver status= Census, Compendium
  • Number of Interaction partner in intact: 35
  • Number of Interaction partner in biogrid: 57
  • Number of Interaction partner in hippie: 208
Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
Cancer Database
Cancer Driver
Number of independent pubication
Interaction Database
Number of missense mutations
Number of disordered residues
Number of mutations in disordered residues
Number of mutations in disordered residues
Number of omim mutations
AARSD1 AARSD1 Q9BTE6 Alanyl-tRNA editing protein Aarsd1 chr17 Not Cancer Driver No 2 intact, hippie, biogrid 40 157 20 20 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 Census, Compendium Yes 1 hippie 139 604 73 73 2
AGA AGA P20933 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase chr4 Not Cancer Driver No 1 hippie 46 78 11 11 12
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 Not Cancer Driver No 1 hippie, biogrid 104 146 26 26 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 Not Cancer Driver No 2 hippie, biogrid 34 103 14 14 0
ASF1A ASF1A Q9Y294 Histone chaperone ASF1A chr6 Not Cancer Driver No 1 hippie, biogrid 18 69 2 2 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 Not Cancer Driver No 1 hippie, biogrid 95 293 39 39 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 Census, Compendium Yes 1 hippie 205 1300 174 174 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 Census, Compendium Yes 1 hippie 469 225 39 39 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 Census, Compendium Yes 1 hippie 338 106 14 14 1
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 Not Cancer Driver No 1 hippie 51 63 8 8 0
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 Not Cancer Driver No 1 hippie 52 0 0 0 0
BACH1_ENST00000286800 BACH1 O14867 Transcription regulator protein BACH1 chr21 Not Cancer Driver No 1 hippie 105 328 39 39 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 Not Cancer Driver No 2 intact, hippie, biogrid 55 402 49 49 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 Census Yes 1 hippie 96 384 49 49 0
BCCIP_ENST00000278100 BCCIP Q9P287 BRCA2 and CDKN1A-interacting protein chr10 Not Cancer Driver No 1 hippie 35 99 16 16 0
BNC2 BNC2 Q6ZN30 Zinc finger protein basonuclin-2 chr9 Not Cancer Driver No 1 hippie 242 682 150 150 1
BORCS8 BORCS8 Q96FH0 BLOC-1-related complex subunit 8 chr19 Not Cancer Driver No 1 hippie 2 56 0 0 0
BPIFB4 BPIFB4 P59827 BPI fold-containing family B member 4 chr20 Not Cancer Driver No 1 hippie 137 74 15 15 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 Census, Compendium Yes 4 intact, hippie 224 1458 174 174 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 Census, Compendium Yes 2 intact, hippie 457 1542 225 225 46
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX Not Cancer Driver No 1 hippie 39 74 7 7 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 Census Yes 1 hippie 174 397 59 59 6
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 Census Yes 1 hippie 96 480 35 35 7
C6orf141 C6orf141 Q5SZD1 Uncharacterized protein C6orf141 chr6 Not Cancer Driver No 2 intact, hippie, biogrid 12 226 9 9 0
CABLES2 CABLES2 Q9BTV7 CDK5 and ABL1 enzyme substrate 2 chr20 Not Cancer Driver No 1 hippie 38 250 11 11 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 Not Cancer Driver No 1 hippie, biogrid 53 126 7 7 1
CAT CAT P04040 Catalase chr11 Not Cancer Driver No 1 hippie 70 176 18 18 0
CCDC24 CCDC24 Q8N4L8 Coiled-coil domain-containing protein 24 chr1 Not Cancer Driver No 1 hippie 36 138 23 23 0
CCDC96 CCDC96 Q2M329 Coiled-coil domain-containing protein 96 chr4 Not Cancer Driver No 1 hippie, biogrid 74 308 41 41 0
CCNA1 CCNA1 P78396 Cyclin-A1 chr13 Not Cancer Driver No 1 hippie 112 82 21 21 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 Not Cancer Driver No 1 hippie 45 186 19 19 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 Not Cancer Driver No 1 hippie 49 145 14 14 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 Census, Compendium Yes 1 hippie 55 31 25 25 0
CCNE1 CCNE1 P24864 G1/S-specific cyclin-E1 chr19 Census Yes 1 hippie 63 142 26 26 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 Not Cancer Driver No 1 hippie, biogrid 216 104 46 46 0
CDC45_ENST00000407835 CDC45 O75419 Cell division control protein 45 homolog chr22 Not Cancer Driver No 1 intact, hippie 73 66 16 16 5
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 Not Cancer Driver No 1 hippie 24 0 0 0 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 Not Cancer Driver No 1 hippie 82 201 33 33 0
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 Not Cancer Driver No 1 hippie, biogrid 127 690 72 72 0
CFAP299_ENST00000358105 CFAP299 Q6V702 Cilia- and flagella-associated protein 299 chr4 Not Cancer Driver No 1 hippie 51 29 7 7 0
CFAP52 CFAP52 Q8N1V2 Cilia- and flagella-associated protein 52 chr17 Not Cancer Driver No 1 hippie 107 4 0 0 0
CFH CFH P08603 Complement factor H chr1 Not Cancer Driver No 1 hippie 355 89 28 28 42
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 Not Cancer Driver No 1 hippie 58 86 16 16 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 Census, Compendium Yes 1 hippie 335 157 130 130 13
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 Not Cancer Driver No 1 hippie 25 201 22 22 2
CLHC1_ENST00000407122 CLHC1 Q8NHS4 Clathrin heavy chain linker domain-containing protein 1 chr2 Not Cancer Driver No 1 hippie 68 15 0 0 0
CNKSR1 CNKSR1 Q969H4 Connector enhancer of kinase suppressor of ras 1 chr1 Not Cancer Driver No 2 hippie, biogrid 118 405 68 68 0
COL11A1 COL11A1 P12107 Collagen alpha-1(XI) chain chr1 Not Cancer Driver No 1 hippie 749 1436 617 617 8
CRYAA CRYAA P02489 Alpha-crystallin A chain chr21 Not Cancer Driver No 1 hippie, biogrid 34 42 11 11 10
CRYL1 CRYL1 Q9Y2S2 Lambda-crystallin homolog chr13 Not Cancer Driver No 1 hippie, biogrid 36 29 3 3 0
CT55 CT55 Q8WUE5 Cancer/testis antigen 55 chrX Not Cancer Driver No 1 hippie 42 40 3 3 0
CWF19L2 CWF19L2 Q2TBE0 CWF19-like protein 2 chr11 Not Cancer Driver No 1 hippie 119 615 83 83 0
DCST2 DCST2 Q5T1A1 DC-STAMP domain-containing protein 2 chr1 Not Cancer Driver No 1 hippie 110 130 15 15 0
DDX3Y_ENST00000336079 DDX3Y O15523 ATP-dependent RNA helicase DDX3Y chrY Not Cancer Driver No 1 hippie 31 289 18 18 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 Not Cancer Driver No 1 hippie 138 326 43 43 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 Not Cancer Driver No 2 intact, hippie 39 49 5 5 0
DNAH9 DNAH9 Q9NYC9 Dynein axonemal heavy chain 9 chr17 Not Cancer Driver No 1 hippie 1009 325 64 64 4
DPPA3 DPPA3 Q6W0C5 Developmental pluripotency-associated protein 3 chr12 Not Cancer Driver No 1 hippie, biogrid 58 105 43 43 0
DSN1 DSN1 Q9H410 Kinetochore-associated protein DSN1 homolog chr20 Not Cancer Driver No 3 intact, hippie, biogrid 45 191 28 28 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 Not Cancer Driver No 1 hippie, biogrid 49 210 25 25 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 Compendium Yes 1 hippie, biogrid 70 273 34 34 0
DYDC1_ENST00000421924 DYDC1 Q8WWB3 DPY30 domain-containing protein 1 chr10 Not Cancer Driver No 1 hippie 29 94 17 17 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 Not Cancer Driver No 1 hippie 505 495 62 62 21
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 Not Cancer Driver No 1 hippie 46 208 20 20 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 Not Cancer Driver No 1 hippie 43 211 14 14 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 Not Cancer Driver No 1 hippie 33 13 0 0 0
EIF2B4_ENST00000347454 EIF2B4 Q9UI10 Translation initiation factor eIF-2B subunit delta chr2 Not Cancer Driver No 1 hippie 57 212 29 29 7
EMSY_ENST00000529032 EMSY Q7Z589 BRCA2-interacting transcriptional repressor EMSY chr11 Not Cancer Driver No 1 hippie 166 1151 147 147 0
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 Census Yes 1 hippie 175 816 121 121 6
ETAA1 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 Not Cancer Driver No 1 hippie 101 735 75 75 0
F8 F8 P00451 Coagulation factor VIII chrX Not Cancer Driver No 1 hippie 414 931 174 174 472
FAM160A2_ENST00000449352 FHIP1B Q8N612 FHF complex subunit HOOK interacting protein 1B chr11 Not Cancer Driver No 1 intact 129 415 54 54 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 Census, Compendium Yes 2 intact, hippie 176 181 14 14 3
FANCE FANCE Q9HB96 Fanconi anemia group E protein chr6 Census Yes 1 hippie 47 199 22 22 0
FANCG FANCG O15287 Fanconi anemia group G protein chr9 Census Yes 1 hippie 64 48 3 3 1
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 Not Cancer Driver No 1 hippie 161 129 20 20 2
FBXL13_ENST00000436908 FBXL13 Q8NEE6 Dynein regulatory complex subunit 6 chr7 Not Cancer Driver No 1 hippie 103 41 5 5 0
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 Not Cancer Driver No 1 hippie 114 177 26 26 7
FLNA FLNA P21333 Filamin-A chrX Census Yes 1 hippie 416 1456 214 214 28
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 Not Cancer Driver No 1 hippie 92 70 13 13 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 Not Cancer Driver No 1 hippie 72 146 3 3 0
GOLGA6L2 GOLGA6L2 Q8N9W4 Golgin subfamily A member 6-like protein 2 chr15 Not Cancer Driver No 1 hippie 57 830 50 50 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 Not Cancer Driver No 1 intact, hippie 28 10 1 1 0
GREB1L GREB1L Q9C091 GREB1-like protein chr18 Not Cancer Driver No 1 hippie 87 480 22 22 25
HMG20B HMG20B Q9P0W2 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related chr19 Not Cancer Driver No 1 hippie 27 237 18 18 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 Not Cancer Driver No 1 hippie 42 227 35 35 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 Not Cancer Driver No 1 hippie, biogrid 52 23 3 3 1
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 Not Cancer Driver No 1 hippie 94 268 35 35 0
HSPB8 HSPB8 Q9UJY1 Heat shock protein beta-8 chr12 Not Cancer Driver No 3 intact, hippie, biogrid 40 130 31 31 5
IER2_ENST00000587885 IER2 Q9BTL4 Immediate early response gene 2 protein chr19 Not Cancer Driver No 1 hippie, biogrid 16 178 13 13 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 Not Cancer Driver No 1 hippie 107 266 27 27 0
KATNAL2_ENST00000356157 KATNAL2 Q8IYT4 Katanin p60 ATPase-containing subunit A-like 2 chr18 Not Cancer Driver No 1 hippie 84 142 30 30 0
KEAP1_ENST00000393623 KEAP1 Q14145 Kelch-like ECH-associated protein 1 chr19 Census, Compendium Yes 1 hippie 237 57 12 12 0
KIF4A KIF4A O95239 Chromosome-associated kinesin KIF4A chrX Not Cancer Driver No 1 hippie 188 674 116 116 0
KLHL40 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 Not Cancer Driver No 1 hippie, biogrid 108 44 8 8 13
KRT2 KRT2 P35908 Keratin, type II cytoskeletal 2 epidermal chr12 Not Cancer Driver No 1 hippie, biogrid 122 335 59 59 15
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie, biogrid 89 52 15 15 0
KRT78 KRT78 Q8N1N4 Keratin, type II cytoskeletal 78 chr12 Not Cancer Driver No 1 hippie, biogrid 96 122 27 27 0
L3MBTL1 L3MBTL1 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 chr20 Not Cancer Driver No 2 intact, hippie, biogrid 116 447 40 40 0
LIMD1 LIMD1 Q9UGP4 LIM domain-containing protein 1 chr3 Not Cancer Driver No 1 hippie 58 428 36 36 0
LMNA LMNA P02545 Prelamin-A/C chr1 Census Yes 1 hippie 68 544 49 49 131
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 Not Cancer Driver No 1 hippie 519 90 17 17 23
LZTS2 LZTS2 Q9BRK4 Leucine zipper putative tumor suppressor 2 chr10 Not Cancer Driver No 1 hippie 78 508 66 66 0
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX Not Cancer Driver No 1 hippie 131 457 71 71 0
MAPK6 MAPK6 Q16659 Mitogen-activated protein kinase 6 chr15 Not Cancer Driver No 1 hippie 79 165 20 20 0
MCPH1 MCPH1 Q8NEM0 Microcephalin chr8 Not Cancer Driver No 1 hippie 110 446 62 62 1
MDC1 MDC1 Q14676 Mediator of DNA damage checkpoint protein 1 chr6 Not Cancer Driver No 1 hippie 249 1829 223 223 0
MDFIC_ENST00000393486 MDFIC Q9P1T7 MyoD family inhibitor domain-containing protein chr7 Not Cancer Driver No 1 hippie 35 143 23 23 0
MFSD13A MFSD13A Q14CX5 Transmembrane protein 180 chr10 Not Cancer Driver No 1 hippie 40 12 0 0 0
MGMT MGMT B4DEE8 Methylated-DNA--protein-cysteine methyltransferase chr10 Census Yes 1 hippie 43 40 15 15 0
MIER2 MIER2 Q8N344 Mesoderm induction early response protein 2 chr19 Not Cancer Driver No 1 hippie, biogrid 72 365 45 45 0
MLF1_ENST00000355893 MLF1 P58340 Myeloid leukemia factor 1 chr3 Census Yes 3 hippie, biogrid 40 243 37 37 0
MMP10 MMP10 P09238 Stromelysin-2 chr11 Not Cancer Driver No 1 hippie 88 38 9 9 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 Not Cancer Driver No 3 hippie, biogrid 43 163 17 17 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX Not Cancer Driver No 2 intact, hippie, biogrid 44 136 21 21 0
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 Not Cancer Driver No 1 intact, hippie 78 283 32 32 0
MTMR6 MTMR6 Q9Y217 Myotubularin-related protein 6 chr13 Not Cancer Driver No 1 hippie 87 68 16 16 0
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 Not Cancer Driver No 1 hippie 275 1215 169 169 5
NAA11 NAA11 Q9BSU3 N-alpha-acetyltransferase 11 chr4 Not Cancer Driver No 1 hippie, biogrid 64 123 31 31 0
NCAPH2_ENST00000420993 NCAPH2 Q6IBW4 Condensin-2 complex subunit H2 chr22 Not Cancer Driver No 2 hippie, biogrid 67 335 39 39 0
NCKAP5 NCKAP5 O14513 Nck-associated protein 5 chr2 Not Cancer Driver No 1 hippie 450 1677 408 408 0
NCL NCL P19338 Nucleolin chr2 Not Cancer Driver No 1 intact, hippie 85 569 68 68 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 Not Cancer Driver No 1 hippie 150 711 79 79 0
NEURL4 NEURL4 Q96JN8 Neuralized-like protein 4 chr17 Not Cancer Driver No 1 intact, hippie 217 751 119 119 0
NIN NIN Q8N4C6 Ninein chr14 Census, Compendium Yes 1 hippie 239 1392 164 164 2
NINL NINL Q9Y2I6 Ninein-like protein chr20 Not Cancer Driver No 1 hippie 230 881 150 150 0
NPM1 NPM1 P06748 Nucleophosmin chr5 Census, Compendium Yes 1 hippie 29 249 22 22 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 Not Cancer Driver No 1 biogrid 144 89 18 18 20
NPY4R_ENST00000612632 NPY4R P50391 Neuropeptide Y receptor type 4 chr10 Not Cancer Driver No 1 biogrid 110 5 2 2 0
NSL1 NSL1 Q96IY1 Kinetochore-associated protein NSL1 homolog chr1 Not Cancer Driver No 1 hippie, biogrid 30 117 12 12 0
NSMCE4A NSMCE4A Q9NXX6 Non-structural maintenance of chromosomes element 4 homolog A chr10 Not Cancer Driver No 3 intact, hippie, biogrid 17 200 5 5 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 Not Cancer Driver No 1 hippie 107 58 27 27 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 Census Yes 13 intact, hippie, biogrid 124 769 77 77 1
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 Not Cancer Driver No 1 intact 119 320 34 34 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 Not Cancer Driver No 1 intact, hippie 30 22 3 3 1
PDS5B PDS5B Q9NTI5 Sister chromatid cohesion protein PDS5 homolog B chr13 Not Cancer Driver No 1 hippie 174 455 61 61 0
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 Not Cancer Driver No 1 biogrid 112 26 5 5 101
PLEC PLEC Q15149 Plectin chr8 Not Cancer Driver No 1 hippie 677 2130 272 272 2
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 Not Cancer Driver No 1 hippie 87 119 13 13 0
PMS1 PMS1 P54277 PMS1 protein homolog 1 chr2 Census Yes 1 hippie 114 283 38 38 0
PMS2 PMS2 P54278 Mismatch repair endonuclease PMS2 chr7 Census, Compendium Yes 1 hippie 117 331 44 44 9
POLH POLH Q9Y253 DNA polymerase eta chr6 Not Cancer Driver No 1 intact, hippie 72 291 20 20 10
POLN_ENST00000382865 POLN Q7Z5Q5 DNA polymerase nu chr4 Not Cancer Driver No 1 hippie 115 247 28 28 0
POLR1E POLR1E Q9GZS1 DNA-directed RNA polymerase I subunit RPA49 chr9 Not Cancer Driver No 1 hippie, biogrid 39 85 6 6 0
POLR2A POLR2A P24928-2 Isoform 2 of DNA-directed RNA polymerase II subunit RPB1 chr17 Census Yes 1 hippie 56 230 20 20 0
PPA2 PPA2 Q9H2U2 Inorganic pyrophosphatase 2, mitochondrial chr4 Not Cancer Driver No 1 hippie 49 71 9 9 9
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 Not Cancer Driver No 2 intact, hippie, biogrid 114 384 53 53 0
PPP1R17 PPP1R17 O96001 Protein phosphatase 1 regulatory subunit 17 chr7 Not Cancer Driver No 1 hippie 39 143 36 36 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 Not Cancer Driver No 1 hippie 41 12 1 1 8
PRELID2 PRELID2 Q8N945 PRELI domain-containing protein 2 chr5 Not Cancer Driver No 1 hippie, biogrid 20 3 0 0 0
PSMD3 PSMD3 O43242 26S proteasome non-ATPase regulatory subunit 3 chr17 Not Cancer Driver No 1 hippie 69 152 19 19 0
PSMD6_ENST00000295901 PSMD6 Q15008 26S proteasome non-ATPase regulatory subunit 6 chr3 Not Cancer Driver No 1 hippie 33 40 3 3 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 Not Cancer Driver No 1 hippie, biogrid 11 52 3 3 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 Not Cancer Driver No 1 hippie 40 63 2 2 0
PYGM PYGM P11217 Glycogen phosphorylase, muscle form chr11 Not Cancer Driver No 1 hippie 153 39 4 4 17
RABL2A_ENST00000393166 RABL2A Q9UBK7 Rab-like protein 2A chr2 Not Cancer Driver No 2 intact, hippie, biogrid 23 44 5 5 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 Census, Compendium Yes 1 intact, hippie 115 421 74 74 3
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 Not Cancer Driver No 1 intact, hippie 50 283 41 41 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 Not Cancer Driver No 1 hippie 157 730 84 84 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 Not Cancer Driver No 1 hippie 47 18 2 2 6
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 Not Cancer Driver No 17 intact, hippie, biogrid 42 47 5 5 3
RELCH RELCH Q9P260 RAB11-binding protein RELCH chr18 Not Cancer Driver No 1 hippie 114 384 29 29 0
RFXANK_ENST00000407360 RFXANK O14593 DNA-binding protein RFXANK chr19 Not Cancer Driver No 1 intact, hippie, biogrid 22 120 6 6 1
RNASEH2A RNASEH2A O75792 Ribonuclease H2 subunit A chr19 Not Cancer Driver No 1 hippie 42 31 3 3 7
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 Not Cancer Driver No 1 hippie 77 471 66 66 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 Not Cancer Driver No 1 hippie 145 732 81 81 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 Not Cancer Driver No 1 hippie 51 98 6 6 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 Not Cancer Driver No 1 hippie 28 114 16 16 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 Not Cancer Driver No 1 hippie 75 204 29 29 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 Not Cancer Driver No 1 hippie, biogrid 48 187 30 30 0
SEM1_ENST00000356686 SEM1 Q6ZVN7 Putative protein SEM1, isoform 2 chr7 Not Cancer Driver No 1 hippie 2 52 1 1 0
SERPINH1_ENST00000358171 SERPINH1 P50454 Serpin H1 chr11 Not Cancer Driver No 1 hippie 51 52 6 6 1
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 Not Cancer Driver No 1 hippie 288 1659 186 186 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 Not Cancer Driver No 1 hippie 84 157 14 14 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 Not Cancer Driver No 1 hippie 52 52 6 6 0
SLC16A14 SLC16A14 Q7RTX9 Monocarboxylate transporter 14 chr2 Not Cancer Driver No 1 hippie 126 52 16 16 0
SLCO1B3_ENST00000381545 SLCO1B3 Q9NPD5 Solute carrier organic anion transporter family member 1B3 chr12 Not Cancer Driver No 1 hippie 208 35 8 8 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 Not Cancer Driver No 1 intact, hippie 149 605 70 70 0
SNX32 SNX32 Q86XE0 Sorting nexin-32 chr11 Not Cancer Driver No 2 hippie, biogrid 64 86 10 10 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 Not Cancer Driver No 1 hippie, biogrid 33 85 7 7 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 Not Cancer Driver No 1 hippie 96 599 71 71 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 Not Cancer Driver No 1 biogrid 82 293 39 39 0
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 Not Cancer Driver No 1 hippie 89 125 14 14 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 Not Cancer Driver No 1 hippie 84 407 40 40 0
SUPT3H_ENST00000371459 SUPT3H O75486 Transcription initiation protein SPT3 homolog chr6 Not Cancer Driver No 1 hippie 49 49 4 4 0
SYCP3_ENST00000392924 SYCP3 Q8IZU3 Synaptonemal complex protein 3 chr12 Not Cancer Driver No 1 intact, hippie 30 124 12 12 0
SYNE3 SYNE3 Q6ZMZ3 Nesprin-3 chr14 Not Cancer Driver No 1 hippie, biogrid 143 236 42 42 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 Not Cancer Driver No 1 hippie 332 396 67 67 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 Not Cancer Driver No 1 hippie, biogrid 28 310 16 16 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 Census Yes 1 hippie 110 212 16 16 31
TEX45 TEX45 Q8NA69 Testis-expressed protein 45 chr19 Not Cancer Driver No 1 intact, hippie 41 415 30 30 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 intact, hippie 227 1632 190 190 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 2 intact, hippie 2891 282 1466 1466 83
TPSAB1 TPSAB1 Q15661 Tryptase alpha/beta-1 chr16 Not Cancer Driver No 1 biogrid 40 28 6 6 0
TRIM29 TRIM29 Q14134 Tripartite motif-containing protein 29 chr11 Not Cancer Driver No 1 hippie 121 351 72 72 0
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 Not Cancer Driver No 1 hippie, biogrid 23 147 13 13 0
TSGA10IP TSGA10IP Q3SY00 Testis-specific protein 10-interacting protein chr11 Not Cancer Driver No 1 hippie, biogrid 79 552 79 79 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 Not Cancer Driver No 1 hippie 118 550 50 50 0
TYK2 TYK2 P29597 Non-receptor tyrosine-protein kinase TYK2 chr19 Not Cancer Driver No 1 biogrid 148 213 29 29 0
UIMC1_ENST00000511320 UIMC1 Q96RL1 BRCA1-A complex subunit RAP80 chr5 Not Cancer Driver No 1 hippie 64 609 51 51 0
UPP1_ENST00000395564 UPP1 Q16831 Uridine phosphorylase 1 chr7 Not Cancer Driver No 1 hippie, biogrid 47 13 3 3 0
UQCC1 UQCC1 Q9NVA1 Ubiquinol-cytochrome-c reductase complex assembly factor 1 chr20 Not Cancer Driver No 1 hippie 46 59 10 10 0
USP11 USP11 P51784 Ubiquitin carboxyl-terminal hydrolase 11 chrX Not Cancer Driver No 2 intact, hippie 140 210 28 28 0
USP21_ENST00000289865 USP21 Q9UK80 Ubiquitin carboxyl-terminal hydrolase 21 chr1 Not Cancer Driver No 1 hippie 95 230 47 47 0
UTP14C UTP14C Q5TAP6 U3 small nucleolar RNA-associated protein 14 homolog C chr13 Not Cancer Driver No 1 hippie 84 657 72 72 0
VIRMA VIRMA Q69YN4 Protein virilizer homolog chr8 Not Cancer Driver No 1 hippie 211 631 93 93 0
VPS28_ENST00000292510 VPS28 Q9UK41 Vacuolar protein sorting-associated protein 28 homolog chr8 Not Cancer Driver No 1 hippie, biogrid 28 31 5 5 0
WTIP WTIP A6NIX2 Wilms tumor protein 1-interacting protein chr19 Not Cancer Driver No 1 hippie 32 217 2 2 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 Census, Compendium Yes 1 hippie 140 33 9 9 0
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 Not Cancer Driver No 3 intact, hippie 24 35 2 2 1
ZNF503 ZNF503 Q96F45 Zinc finger protein 503 chr10 Not Cancer Driver No 1 hippie 26 446 14 14 0
ZNF707_ENST00000358656 ZNF707 Q96C28 Zinc finger protein 707 chr8 Not Cancer Driver No 1 hippie 53 138 21 21 0
ZYG11A ZYG11A Q6WRX3 Protein zyg-11 homolog A chr1 Not Cancer Driver No 1 hippie 52 7 0 0 0