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ATF3_ENST00000366987 ,ATF3 ,P18847
  • Number of Interaction partner in intact: 0
  • Number of Interaction partner in biogrid: 8
  • Number of Interaction partner in hippie: 96
Identifier UniProt Gene UniProt Accession UniProt Name Chromosome Cancer Database Cancer Driver Number of independent pubication Interaction Database Number of missense mutations Number of disordered residues Number of mutations in disordered residues Number of mutations in disordered residues Number of omim mutations
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 Not Cancer Driver No 1 hippie 112 43 5 5 5
APBB2_ENST00000295974 APBB2 Q92870 Amyloid beta precursor protein binding family B member 2 chr4 Not Cancer Driver No 1 hippie 88 419 51 51 0
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 Not Cancer Driver No 1 hippie 70 149 14 14 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 Not Cancer Driver No 1 hippie 65 451 58 58 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 Not Cancer Driver No 1 hippie 23 118 14 14 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 Not Cancer Driver No 1 hippie 53 259 38 38 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 Not Cancer Driver No 1 hippie 45 468 45 45 0
ATXN1 ATXN1 P54253 Ataxin-1 chr6 Not Cancer Driver No 1 hippie 193 604 168 168 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 Not Cancer Driver No 1 hippie 28 119 25 25 0
BATF3 BATF3 Q9NR55 Basic leucine zipper transcriptional factor ATF-like 3 chr1 Not Cancer Driver No 1 hippie 18 127 18 18 0
CALD1 CALD1 Q05682 Caldesmon chr7 Not Cancer Driver No 1 hippie 133 793 133 133 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 Not Cancer Driver No 1 hippie 40 41 2 2 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 Not Cancer Driver No 1 hippie 37 19 0 0 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 Census, Compendium Yes 1 hippie 12 342 12 12 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 Not Cancer Driver No 1 hippie 3 276 2 2 0
CEBPE CEBPE Q15744 CCAAT/enhancer-binding protein epsilon chr14 Not Cancer Driver No 1 hippie 56 257 53 53 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 Not Cancer Driver No 1 hippie 13 141 12 12 0
CORO1B CORO1B Q9BR76 Coronin-1B chr11 Not Cancer Driver No 1 hippie 41 138 10 10 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 Not Cancer Driver No 1 hippie 33 168 11 11 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 Census, Compendium Yes 1 hippie 412 1796 247 247 33
CRK CRK P46108 Adapter molecule crk chr17 Not Cancer Driver No 1 hippie 30 197 23 23 0
DBP DBP Q10586 D site-binding protein chr19 Not Cancer Driver No 1 hippie 24 280 18 18 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 Census Yes 1 hippie 172 817 111 111 11
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 Census Yes 2 hippie, biogrid 29 160 27 27 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 Not Cancer Driver No 1 hippie 83 10 1 1 0
DOK5 DOK5 Q9P104 Docking protein 5 chr20 Not Cancer Driver No 1 hippie 87 15 7 7 0
EEF1B2_ENST00000236957 EEF1B2 P24534 Elongation factor 1-beta chr2 Not Cancer Driver No 1 hippie 63 71 11 11 0
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 Not Cancer Driver No 1 hippie 211 829 117 117 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 Not Cancer Driver No 1 hippie 25 53 8 8 7
EWSR1_ENST00000397938 EWSR1 Q01844 RNA-binding protein EWS chr22 Census, Compendium Yes 1 hippie 94 646 93 93 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 Census, Compendium Yes 1 hippie, biogrid 173 241 26 26 37
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 Not Cancer Driver No 1 hippie 30 0 0 0 0
FOS FOS P01100 Protein c-Fos chr14 Not Cancer Driver No 1 hippie 45 245 33 33 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 Not Cancer Driver No 1 hippie 24 271 24 24 0
FOSL2 FOSL2 P15408 Fos-related antigen 2 chr2 Not Cancer Driver No 1 hippie 54 323 54 54 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 Not Cancer Driver No 1 hippie 56 146 13 13 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 Not Cancer Driver No 1 hippie 47 135 10 10 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 Not Cancer Driver No 1 hippie 67 121 11 11 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 Not Cancer Driver No 1 hippie 65 61 8 8 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 Not Cancer Driver No 1 hippie 182 749 132 132 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 Not Cancer Driver No 1 hippie 118 718 73 73 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX Not Cancer Driver No 1 hippie 178 409 59 59 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 Census, Compendium Yes 1 hippie 106 257 37 37 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 Census, Compendium Yes 1 hippie 100 254 43 43 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 Census, Compendium Yes 1 hippie 14 34 4 4 0
IGSF21 IGSF21 Q96ID5 Immunoglobulin superfamily member 21 chr1 Not Cancer Driver No 1 hippie, biogrid 119 183 47 47 0
JUN JUN P05412 Transcription factor Jun chr1 Census Yes 1 hippie 35 281 25 25 0
JUNB JUNB P17275 Transcription factor JunB chr19 Not Cancer Driver No 3 hippie, biogrid 20 305 16 16 0
JUND JUND P17535 Transcription factor JunD chr19 Not Cancer Driver No 1 hippie 21 313 19 19 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 Not Cancer Driver No 1 hippie 65 173 21 21 3
KRT38 KRT38 O76015 Keratin, type I cuticular Ha8 chr17 Not Cancer Driver No 1 hippie, biogrid 89 52 15 15 0
LMO1 LMO1 P25800 Rhombotin-1 chr11 Census Yes 1 hippie, biogrid 23 0 0 0 0
LRIF1 LRIF1 Q5T3J3 Ligand-dependent nuclear receptor-interacting factor 1 chr1 Not Cancer Driver No 1 hippie, biogrid 116 520 74 74 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 Census Yes 1 hippie 35 301 34 34 10
MAFF_ENST00000426621 MAFF Q9ULX9 Transcription factor MafF chr22 Not Cancer Driver No 1 hippie 9 118 7 7 0
MAFG MAFG O15525 Transcription factor MafG chr17 Not Cancer Driver No 1 hippie 5 132 5 5 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 Census, Compendium Yes 1 hippie 56 297 37 37 0
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 Not Cancer Driver No 1 hippie 62 454 56 56 0
MEN1 MEN1 O00255 Menin chr11 Census, Compendium Yes 1 hippie 73 228 15 15 90
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 Census, Compendium Yes 1 hippie 80 299 46 46 0
MYL6B MYL6B P14649 Myosin light chain 6B chr12 Not Cancer Driver No 1 hippie 24 109 14 14 0
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 Not Cancer Driver No 1 hippie 173 713 130 130 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 Census, Compendium Yes 1 hippie 228 402 62 62 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 Not Cancer Driver No 1 hippie 104 344 38 38 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 Not Cancer Driver No 1 hippie 92 362 37 37 12
NUF2_ENST00000367900 NUF2 Q9BZD4 Kinetochore protein Nuf2 chr1 Not Cancer Driver No 1 hippie 97 74 20 20 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 Not Cancer Driver No 1 hippie 32 238 23 23 0
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 Not Cancer Driver No 1 hippie 33 303 24 24 0
RELA RELA Q04206 Transcription factor p65 chr11 Compendium Yes 1 hippie 75 400 48 48 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 Not Cancer Driver No 1 hippie 287 1355 164 164 0
SH2D1A SH2D1A O60880 SH2 domain-containing protein 1A chrX Not Cancer Driver No 1 hippie 40 24 8 8 19
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 Census, Compendium Yes 1 hippie 79 137 12 12 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 Census, Compendium Yes 1 hippie 97 111 19 19 5
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 Census, Compendium Yes 1 hippie 349 1072 195 195 5
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 Not Cancer Driver No 1 hippie 21 107 13 13 5
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 Census Yes 1 hippie 53 356 48 48 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 Not Cancer Driver No 1 hippie 131 144 25 25 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 Census, Compendium Yes 1 hippie 110 152 15 15 19
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 Not Cancer Driver No 1 hippie 10 76 7 7 0
SUMO2 SUMO2 P61956 Small ubiquitin-related modifier 2 chr17 Not Cancer Driver No 1 hippie 9 69 6 6 0
SUMO3_ENST00000332859 SUMO3 P55854 Small ubiquitin-related modifier 3 chr21 Not Cancer Driver No 1 hippie 7 87 5 5 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX Not Cancer Driver No 1 hippie 59 15 1 1 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 Not Cancer Driver No 1 hippie 51 202 15 15 27
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 Not Cancer Driver No 1 hippie 66 220 31 31 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 Not Cancer Driver No 1 hippie 227 1632 190 190 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 Census, Compendium Yes 2 hippie, biogrid 2891 282 1466 1466 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 Census, Compendium Yes 1 hippie 229 398 143 143 28
TP73 TP73 O15350 Tumor protein p73 chr1 Not Cancer Driver No 1 hippie 82 443 55 55 0
TPM4_ENST00000300933 TPM4 P67936 Tropomyosin alpha-4 chain chr19 Census Yes 1 hippie 28 216 28 28 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 Not Cancer Driver No 1 hippie 59 225 20 20 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 Not Cancer Driver No 1 hippie 16 16 3 3 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 Not Cancer Driver No 1 hippie 170 165 15 15 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 Not Cancer Driver No 1 hippie 172 228 30 30 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 Not Cancer Driver No 1 hippie 33 34 7 7 4
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 Not Cancer Driver No 1 hippie 146 329 36 36 0
ZNF212 ZNF212 Q9UDV6 Zinc finger protein 212 chr7 Not Cancer Driver No 1 hippie 68 289 34 34 0