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SMG5 ,SMG5 ,Q9UPR3
  • Uniprot Accession= Q9UPR3
  • Ensembl Transcript= ENST00000361813.5
  • Uniprot Name= SMG5
  • Name= Nonsense-mediated mRNA decay factor SMG5
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 18
GO term GO name GO namespace GO def
GO:0035303 regulation of dephosphorylation biological_process Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule. [GOC:bf]
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay biological_process The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins. [GOC:krc, GOC:ma, PMID:10025395]
GO:0042826 histone deacetylase binding molecular_function Binding to histone deacetylase. [GOC:jl]
GO:0032204 regulation of telomere maintenance biological_process Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA. [GOC:mah]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]
GO:0006406 mRNA export from nucleus biological_process The directed movement of mRNA from the nucleus to the cytoplasm. [GOC:ma]
GO:0019903 protein phosphatase binding molecular_function Binding to a protein phosphatase. [GOC:jl]
GO:0032210 regulation of telomere maintenance via telomerase biological_process Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase. [GOC:mah]
GO:0005488 binding molecular_function The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. [GOC:ceb, GOC:mah, ISBN:0198506732]
GO:0019899 enzyme binding molecular_function Binding to an enzyme, a protein with catalytic activity. [GOC:jl]
GO:0005697 telomerase holoenzyme complex cellular_component Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits. [PMID:11884619]
GO:0019902 phosphatase binding molecular_function Binding to a phosphatase. [GOC:jl]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0070034 telomerase RNA binding molecular_function Binding to the telomerase RNA template. [GOC:krc, PMID:16884717]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0031625 ubiquitin protein ligase binding molecular_function Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins. [GOC:vp]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0042162 telomeric DNA binding molecular_function Binding to a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end. [GOC:jl, SO:0000624]