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Total number of protein in "GO:0019903" GO term:  120

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AC011195.2 IGBP1P2 A0A1W2PR95 HCG1642624, isoform CRA_a chr17 GO:0019903 Not Cancer Driver No 6 0.018 201 4 0.02 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0019903 Not Cancer Driver No 419 0.335 215 38 0.177 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0019903 Not Cancer Driver No 37 0.087 405 34 0.084 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0019903 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0019903 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANAPC5 ANAPC5 Q9UJX4 Anaphase-promoting complex subunit 5 chr12 GO:0019903 Not Cancer Driver No 94 0.125 41 4 0.098 0
ANK1_ENST00000347528 ANK1 P16157 Ankyrin-1 chr8 GO:0019903 Census Yes 405 0.215 810 171 0.211 3
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0019903 Not Cancer Driver No 127 0.135 521 71 0.136 2
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0019903 Not Cancer Driver No 126 0.115 316 31 0.098 1
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0019903 Not Cancer Driver No 17 0.152 112 17 0.152 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0019903 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0019903 Census, Compendium Yes 24 0.1 72 5 0.069 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:0019903 Not Cancer Driver No 16 0.086 133 10 0.075 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0019903 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BOD1L2 BOD1L2 Q8IYS8 Biorientation of chromosomes in cell division protein 1-like 2 chr18 GO:0019903 Not Cancer Driver No 29 0.169 144 26 0.181 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:0019903 Not Cancer Driver No 48 0.124 94 9 0.096 0
CD22 CD22 P20273 B-cell receptor CD22 chr19 GO:0019903 Not Cancer Driver No 173 0.204 290 66 0.228 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0019903 Not Cancer Driver No 119 0.327 177 50 0.282 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0019903 Not Cancer Driver No 179 0.217 289 75 0.26 0
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0019903 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0019903 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0019903 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0019903 Not Cancer Driver No 64 0.122 241 25 0.104 0
CLEC12B CLEC12B Q2HXU8 C-type lectin domain family 12 member B chr12 GO:0019903 Not Cancer Driver No 34 0.123 57 8 0.14 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0019903 Census Yes 133 0.137 124 17 0.137 20
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0019903 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0019903 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTTNBP2NL CTTNBP2NL Q9P2B4 CTTNBP2 N-terminal-like protein chr1 GO:0019903 Not Cancer Driver No 82 0.128 559 78 0.14 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0019903 Not Cancer Driver No 131 0.11 681 68 0.1 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0019903 Not Cancer Driver No 116 0.16 232 55 0.237 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0019903 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0019903 Not Cancer Driver No 149 0.134 410 51 0.124 1
ENSA_ENST00000369014 ENSA O43768 Alpha-endosulfine chr1 GO:0019903 Not Cancer Driver No 15 0.124 121 15 0.124 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0019903 Census, Compendium Yes 275 0.219 314 41 0.131 1
FBXL2 FBXL2 Q9UKC9 F-box/LRR-repeat protein 2 chr3 GO:0019903 Not Cancer Driver No 48 0.113 0 0 0.0 0
FCRL2 FCRL2 Q96LA5 Fc receptor-like protein 2 chr1 GO:0019903 Not Cancer Driver No 116 0.228 76 14 0.184 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0019903 Not Cancer Driver No 193 0.263 217 44 0.203 0
FCRL6 FCRL6 Q6DN72 Fc receptor-like protein 6 chr1 GO:0019903 Not Cancer Driver No 85 0.196 155 24 0.155 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0019903 Census, Compendium Yes 253 0.186 259 41 0.158 13
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0019903 Census, Compendium Yes 81 0.124 584 75 0.128 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0019903 Not Cancer Driver No 173 0.271 229 66 0.288 19
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0019903 Not Cancer Driver No 41 0.108 20 0 0.0 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0019903 Not Cancer Driver No 28 0.129 10 1 0.1 0
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0019903 Not Cancer Driver No 308 0.276 179 22 0.123 0
GTF2F1 GTF2F1 P35269 General transcription factor IIF subunit 1 chr19 GO:0019903 Not Cancer Driver No 63 0.122 426 48 0.113 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0019903 Not Cancer Driver No 94 0.117 268 35 0.131 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:0019903 Not Cancer Driver No 51 0.15 193 28 0.145 0
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0019903 Not Cancer Driver No 108 0.151 76 13 0.171 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0019903 Not Cancer Driver No 183 0.11 351 35 0.1 0
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0019903 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0019903 Not Cancer Driver No 156 0.132 107 13 0.121 0
JAK1 JAK1 P23458 Tyrosine-protein kinase JAK1 chr1 GO:0019903 Census, Compendium Yes 147 0.127 120 7 0.058 2
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0019903 Census, Compendium Yes 167 0.149 63 10 0.159 7
JUP JUP P14923 Junction plakoglobin chr17 GO:0019903 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0019903 Not Cancer Driver No 88 0.105 251 17 0.068 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0019903 Not Cancer Driver No 60 0.141 31 6 0.194 3
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 GO:0019903 Not Cancer Driver No 92 0.132 409 59 0.144 0
KIFAP3 KIFAP3 Q92845 Kinesin-associated protein 3 chr1 GO:0019903 Not Cancer Driver No 116 0.146 71 10 0.141 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0019903 Census Yes 86 0.169 94 13 0.138 1
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0019903 Not Cancer Driver No 15 0.06 133 6 0.045 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0019903 Not Cancer Driver No 162 0.362 277 115 0.415 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0019903 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0019903 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0019903 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0019903 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0019903 Not Cancer Driver No 128 0.169 750 126 0.168 18
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0019903 Not Cancer Driver No 90 0.102 389 44 0.113 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0019903 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0019903 Not Cancer Driver No 95 0.09 98 9 0.092 0
MTMR3 MTMR3 Q13615 Myotubularin-related protein 3 chr22 GO:0019903 Not Cancer Driver No 130 0.109 501 66 0.132 0
MTMR4 MTMR4 Q9NYA4 Myotubularin-related protein 4 chr17 GO:0019903 Not Cancer Driver No 147 0.123 474 59 0.124 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0019903 Not Cancer Driver No 60 0.109 45 7 0.156 0
MVP MVP Q14764 Major vault protein chr16 GO:0019903 Not Cancer Driver No 141 0.158 285 31 0.109 0
MYO16_ENST00000357550 MYO16 Q9Y6X6 Unconventional myosin-XVI chr13 GO:0019903 Not Cancer Driver No 412 0.222 681 112 0.164 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:0019903 Not Cancer Driver No 50 0.189 197 38 0.193 2
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0019903 Not Cancer Driver No 61 0.137 92 19 0.207 0
PDLIM4 PDLIM4 P50479 PDZ and LIM domain protein 4 chr5 GO:0019903 Not Cancer Driver No 42 0.127 238 28 0.118 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0019903 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0019903 Not Cancer Driver No 96 0.132 418 47 0.112 3
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0019903 Not Cancer Driver No 35 0.091 146 9 0.062 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 GO:0019903 Not Cancer Driver No 37 0.117 16 0 0.0 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:0019903 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0019903 Not Cancer Driver No 67 0.128 139 18 0.129 0
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 GO:0019903 Not Cancer Driver No 82 0.093 471 47 0.1 0
PPP6R2_ENST00000216061 PPP6R2 O75170 Serine/threonine-protein phosphatase 6 regulatory subunit 2 chr22 GO:0019903 Not Cancer Driver No 103 0.107 491 63 0.128 0
PPP6R3_ENST00000393800 PPP6R3 Q5H9R7 Serine/threonine-protein phosphatase 6 regulatory subunit 3 chr11 GO:0019903 Not Cancer Driver No 108 0.124 389 52 0.134 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0019903 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0019903 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0019903 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPRT_ENST00000373187 PTPRT O14522 Receptor-type tyrosine-protein phosphatase T chr20 GO:0019903 Census, Compendium Yes 535 0.371 299 125 0.418 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0019903 Not Cancer Driver No 62 0.105 341 24 0.07 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0019903 Not Cancer Driver No 34 0.107 13 0 0.0 0
ROS1 ROS1 P08922 Proto-oncogene tyrosine-protein kinase ROS chr6 GO:0019903 Census Yes 498 0.212 191 55 0.288 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0019903 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0019903 Not Cancer Driver No 45 0.086 226 26 0.115 0
SHOC2 SHOC2 Q9UQ13 Leucine-rich repeat protein SHOC-2 chr10 GO:0019903 Not Cancer Driver No 55 0.095 110 12 0.109 2
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0019903 Census, Compendium Yes 96 0.19 281 51 0.181 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0019903 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0019903 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0019903 Not Cancer Driver No 89 0.109 251 29 0.116 1
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 GO:0019903 Not Cancer Driver No 132 0.13 295 51 0.173 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 GO:0019903 Not Cancer Driver No 134 0.118 664 82 0.123 0
SNX3 SNX3 O60493 Sorting nexin-3 chr6 GO:0019903 Not Cancer Driver No 21 0.13 37 4 0.108 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0019903 Not Cancer Driver No 16 0.104 93 9 0.097 79
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0019903 Not Cancer Driver No 47 0.122 25 2 0.08 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0019903 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0019903 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0019903 Census, Compendium Yes 106 0.125 325 44 0.135 0
STRN STRN O43815 Striatin chr2 GO:0019903 Census, Compendium Yes 97 0.124 348 43 0.124 0
STRN3 STRN3 Q13033 Striatin-3 chr14 GO:0019903 Not Cancer Driver No 93 0.117 366 42 0.115 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 GO:0019903 Not Cancer Driver No 84 0.112 407 40 0.098 0
STX17_ENST00000534052 STX17 P56962 Syntaxin-17 chr9 GO:0019903 Not Cancer Driver No 27 0.089 81 4 0.049 0
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0019903 Not Cancer Driver No 55 0.176 18 3 0.167 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0019903 Not Cancer Driver No 101 0.139 42 5 0.119 12
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0019903 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0019903 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0019903 Compendium Yes 61 0.107 101 9 0.089 1
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0019903 Not Cancer Driver No 88 0.109 186 16 0.086 16
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0019903 Not Cancer Driver No 65 0.137 180 18 0.1 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0019903 Census Yes 32 0.125 41 3 0.073 0