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SH2D1B ,SH2D1B ,O14796
  • Uniprot Accession= O14796
  • Ensembl Transcript= ENST00000367929.2
  • Uniprot Name= SH2D1B
  • Name= SH2 domain-containing protein 1B
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 30
GO term GO name GO namespace GO def
GO:0045089 positive regulation of innate immune response biological_process Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. [GOC:ebc]
GO:0050776 regulation of immune response biological_process Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai]
GO:0002682 regulation of immune system process biological_process Any process that modulates the frequency, rate, or extent of an immune system process. [GOC:add]
GO:0045088 regulation of innate immune response biological_process Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. [GOC:ebc]
GO:0050789 regulation of biological process biological_process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:ai, GOC:go_curators]
GO:0002705 positive regulation of leukocyte mediated immunity biological_process Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add]
GO:0002708 positive regulation of lymphocyte mediated immunity biological_process Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add]
GO:0048583 regulation of response to stimulus biological_process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0002250 adaptive immune response biological_process An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). [GO_REF:0000022, GOC:add, ISBN:0781735149]
GO:0048518 positive regulation of biological process biological_process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. [GOC:jid]
GO:0030674 protein-macromolecule adaptor activity molecular_function The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid. [GOC:bf, GOC:mah, GOC:vw]
GO:0045087 innate immune response biological_process Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. [GO_REF:0000022, GOC:add, GOC:ebc, GOC:mtg_sensu]
GO:0002833 positive regulation of response to biotic stimulus biological_process Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. [GOC:add]
GO:0002831 regulation of response to biotic stimulus biological_process Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. [GOC:add]
GO:0002706 regulation of lymphocyte mediated immunity biological_process Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. [GOC:add]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0031349 positive regulation of defense response biological_process Any process that activates or increases the frequency, rate or extent of a defense response. [GOC:mah]
GO:0032103 positive regulation of response to external stimulus biological_process Any process that activates, maintains or increases the rate of a response to an external stimulus. [GOC:mah]
GO:0032101 regulation of response to external stimulus biological_process Any process that modulates the frequency, rate or extent of a response to an external stimulus. [GOC:mah]
GO:0002697 regulation of immune effector process biological_process Any process that modulates the frequency, rate, or extent of an immune effector process. [GOC:add]
GO:0002684 positive regulation of immune system process biological_process Any process that activates or increases the frequency, rate, or extent of an immune system process. [GOC:add]
GO:0031347 regulation of defense response biological_process Any process that modulates the frequency, rate or extent of a defense response. [GOC:mah]
GO:0050778 positive regulation of immune response biological_process Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. [GOC:ai]
GO:0048584 positive regulation of response to stimulus biological_process Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. [GOC:jid]
GO:0002699 positive regulation of immune effector process biological_process Any process that activates or increases the frequency, rate, or extent of an immune effector process. [GOC:add]
GO:0080134 regulation of response to stress biological_process Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). [GOC:dhl]
GO:0065007 biological regulation biological_process Any process that modulates a measurable attribute of any biological process, quality or function. [GOC:dph, GOC:isa_complete, GOC:mah, GOC:pr, GOC:vw]
GO:0002703 regulation of leukocyte mediated immunity biological_process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. [GOC:add]
GO:0002366 leukocyte activation involved in immune response biological_process A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. [GOC:add, ISBN:0781735149]