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MKNK1 ,MKNK1 ,Q9BUB5
  • Uniprot Accession= Q9BUB5
  • Ensembl Transcript= ENST00000371946.8
  • Uniprot Name= MKNK1
  • Name= MAP kinase-interacting serine/threonine-protein kinase 1
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 22
GO term GO name GO namespace GO def
GO:0018105 peptidyl-serine phosphorylation biological_process The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine. [RESID:AA0037]
GO:0046777 protein autophosphorylation biological_process The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation). [ISBN:0198506732]
GO:0016773 phosphotransferase activity, alcohol group as acceptor molecular_function Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). [GOC:jl]
GO:0006417 regulation of translation biological_process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. [GOC:isa_complete]
GO:0140096 catalytic activity, acting on a protein molecular_function Catalytic activity that acts to modify a protein. [GOC:molecular_function_refactoring, GOC:pdt]
GO:0004674 protein serine/threonine kinase activity molecular_function Catalysis of the reactions
GO:0016301 kinase activity molecular_function Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [ISBN:0198506732]
GO:0004712 protein serine/threonine/tyrosine kinase activity molecular_function Catalysis of the reactions
GO:0035556 intracellular signal transduction biological_process The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. [GOC:bf, GOC:jl, GOC:signaling, ISBN:3527303782]
GO:0005737 cytoplasm cellular_component The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. [ISBN:0198547684]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005515 protein binding molecular_function Binding to a protein. [GOC:go_curators]
GO:0016740 transferase activity molecular_function Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. [ISBN:0198506732]
GO:0003824 catalytic activity molecular_function Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [GOC:vw, ISBN:0198506732]
GO:0004672 protein kinase activity molecular_function Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction
GO:0005516 calmodulin binding molecular_function Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. [GOC:krc]
GO:0005524 ATP binding molecular_function Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. [ISBN:0198506732]
GO:0006468 protein phosphorylation biological_process The process of introducing a phosphate group on to a protein. [GOC:hb]
GO:0016772 transferase activity, transferring phosphorus-containing groups molecular_function Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). [GOC:jl, ISBN:0198506732]
GO:0005829 cytosol cellular_component The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. [GOC:hjd, GOC:jl]
GO:0046872 metal ion binding molecular_function Binding to a metal ion. [GOC:ai]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]