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INKA2 ,INKA2 ,Q9NTI7
  • Uniprot Accession= Q9NTI7
  • Ensembl Transcript= ENST00000357260.5
  • Uniprot Name= INKA2
  • Name= PAK4-inhibitor INKA2
  • Chromosome= chr1
  • Driver status= Not Cancer Driver
  • Number of GO Term: 10
GO term GO name GO namespace GO def
GO:0098772 molecular function regulator molecular_function A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. [GOC:dos, GOC:pt]
GO:0004857 enzyme inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of an enzyme. [GOC:ai, GOC:ebc]
GO:0030234 enzyme regulator activity molecular_function Binds to and modulates the activity of an enzyme. [GOC:dph, GOC:mah, GOC:tb]
GO:0019887 protein kinase regulator activity molecular_function Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. [GOC:ai]
GO:0043086 negative regulation of catalytic activity biological_process Any process that stops or reduces the activity of an enzyme. [GOC:ebc, GOC:jl, GOC:tb, GOC:vw]
GO:0019901 protein kinase binding molecular_function Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. [GOC:jl]
GO:0019207 kinase regulator activity molecular_function Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. [GOC:ai]
GO:0004860 protein kinase inhibitor activity molecular_function Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein. [GOC:ai]
GO:0005654 nucleoplasm cellular_component That part of the nuclear content other than the chromosomes or the nucleolus. [GOC:ma, ISBN:0124325653]
GO:0005634 nucleus cellular_component A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. [GOC:go_curators]