Total number of protein in "GO:0019887" GO term: 84
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0019887 | Census, Compendium | Yes | 55 | 0.108 | 360 | 39 | 0.108 | 0 |
| AFAP1L2 | AFAP1L2 | Q8N4X5 | Actin filament-associated protein 1-like 2 | chr10 | GO:0019887 | Not Cancer Driver | No | 86 | 0.105 | 558 | 59 | 0.106 | 0 |
| ALKAL1 | ALKAL1 | Q6UXT8 | ALK and LTK ligand 1 | chr8 | GO:0019887 | Not Cancer Driver | No | 18 | 0.14 | 49 | 3 | 0.061 | 0 |
| ALKAL2 | ALKAL2 | Q6UX46 | ALK and LTK ligand 2 | chr2 | GO:0019887 | Not Cancer Driver | No | 7 | 0.046 | 31 | 0 | 0.0 | 0 |
| ANGPT4 | ANGPT4 | Q9Y264 | Angiopoietin-4 | chr20 | GO:0019887 | Not Cancer Driver | No | 104 | 0.207 | 150 | 32 | 0.213 | 0 |
| ANKRD54 | ANKRD54 | Q6NXT1 | Ankyrin repeat domain-containing protein 54 | chr22 | GO:0019887 | Not Cancer Driver | No | 26 | 0.087 | 188 | 12 | 0.064 | 0 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0019887 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| CAMK2N1 | CAMK2N1 | Q7Z7J9 | Calcium/calmodulin-dependent protein kinase II inhibitor 1 | chr1 | GO:0019887 | Not Cancer Driver | No | 10 | 0.128 | 72 | 9 | 0.125 | 0 |
| CAMK2N2 | CAMK2N2 | Q96S95 | Calcium/calmodulin-dependent protein kinase II inhibitor 2 | chr3 | GO:0019887 | Not Cancer Driver | No | 6 | 0.076 | 74 | 5 | 0.068 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0019887 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CCNB1 | CCNB1 | P14635 | G2/mitotic-specific cyclin-B1 | chr5 | GO:0019887 | Not Cancer Driver | No | 49 | 0.113 | 145 | 14 | 0.097 | 0 |
| CCNK | CCNK | O75909 | Cyclin-K | chr14 | GO:0019887 | Not Cancer Driver | No | 39 | 0.067 | 347 | 15 | 0.043 | 1 |
| CCNT1 | CCNT1 | O60563 | Cyclin-T1 | chr12 | GO:0019887 | Not Cancer Driver | No | 85 | 0.117 | 495 | 61 | 0.123 | 0 |
| CCNT2 | CCNT2 | O60583 | Cyclin-T2 | chr2 | GO:0019887 | Not Cancer Driver | No | 76 | 0.104 | 471 | 52 | 0.11 | 0 |
| CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:0019887 | Not Cancer Driver | No | 38 | 0.111 | 94 | 6 | 0.064 | 0 |
| CCNYL1 | CCNYL1 | Q8N7R7 | Cyclin-Y-like protein 1 | chr2 | GO:0019887 | Not Cancer Driver | No | 31 | 0.086 | 100 | 8 | 0.08 | 0 |
| CDC37 | CDC37 | Q16543 | Hsp90 co-chaperone Cdc37 | chr19 | GO:0019887 | Not Cancer Driver | No | 52 | 0.138 | 214 | 31 | 0.145 | 0 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0019887 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CDK5R2 | CDK5R2 | Q13319 | Cyclin-dependent kinase 5 activator 2 | chr2 | GO:0019887 | Not Cancer Driver | No | 14 | 0.038 | 204 | 5 | 0.025 | 0 |
| CDKN1A_ENST00000373711 | CDKN1A | P38936 | Cyclin-dependent kinase inhibitor 1 | chr6 | GO:0019887 | Census, Compendium | Yes | 48 | 0.293 | 121 | 30 | 0.248 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0019887 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN1C | CDKN1C | P49918 | Cyclin-dependent kinase inhibitor 1C | chr11 | GO:0019887 | Not Cancer Driver | No | 2 | 0.006 | 256 | 1 | 0.004 | 7 |
| CDKN2A_ENST00000304494 | CDKN2A | P42771 | Cyclin-dependent kinase inhibitor 2A | chr9 | GO:0019887 | Census, Compendium | Yes | 166 | 1.064 | 83 | 88 | 1.06 | 36 |
| CDKN2B | CDKN2B | P42772 | Cyclin-dependent kinase 4 inhibitor B | chr9 | GO:0019887 | Not Cancer Driver | No | 15 | 0.109 | 67 | 3 | 0.045 | 0 |
| CDKN2C_ENST00000371761 | CDKN2C | P42773 | Cyclin-dependent kinase 4 inhibitor C | chr1 | GO:0019887 | Census, Compendium | Yes | 23 | 0.137 | 49 | 6 | 0.122 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0019887 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0019887 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
| CIT_ENST00000261833 | CIT | O14578 | Citron Rho-interacting kinase | chr12 | GO:0019887 | Not Cancer Driver | No | 284 | 0.14 | 1017 | 160 | 0.157 | 3 |
| CKS1B | CKS1B | P61024 | Cyclin-dependent kinases regulatory subunit 1 | chr1 | GO:0019887 | Not Cancer Driver | No | 10 | 0.127 | 10 | 0 | 0.0 | 0 |
| CKS2 | CKS2 | P33552 | Cyclin-dependent kinases regulatory subunit 2 | chr9 | GO:0019887 | Not Cancer Driver | No | 9 | 0.114 | 10 | 2 | 0.2 | 0 |
| CSNK2B_ENST00000375866 | CSNK2B | P67870 | Casein kinase II subunit beta | chr6 | GO:0019887 | Not Cancer Driver | No | 20 | 0.093 | 19 | 0 | 0.0 | 4 |
| CXCL10 | CXCL10 | P02778 | C-X-C motif chemokine 10 | chr4 | GO:0019887 | Not Cancer Driver | No | 19 | 0.194 | 12 | 4 | 0.333 | 0 |
| DGKQ | DGKQ | P52824 | Diacylglycerol kinase theta | chr4 | GO:0019887 | Not Cancer Driver | No | 56 | 0.059 | 264 | 11 | 0.042 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0019887 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0019887 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| ELP3 | ELP3 | Q9H9T3 | Elongator complex protein 3 | chr8 | GO:0019887 | Not Cancer Driver | No | 60 | 0.11 | 19 | 4 | 0.211 | 0 |
| ELP4_ENST00000640961 | ELP4 | Q96EB1 | Elongator complex protein 4 | chr11 | GO:0019887 | Not Cancer Driver | No | 60 | 0.142 | 55 | 4 | 0.073 | 0 |
| ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0019887 | Census, Compendium | Yes | 298 | 0.222 | 396 | 70 | 0.177 | 3 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0019887 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0019887 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FGFR1OP | CEP43 | O95684 | Centrosomal protein 43 | chr6 | GO:0019887 | Not Cancer Driver | No | 43 | 0.108 | 272 | 33 | 0.121 | 0 |
| GAS6 | GAS6 | Q14393 | Growth arrest-specific protein 6 | chr13 | GO:0019887 | Not Cancer Driver | No | 82 | 0.121 | 42 | 6 | 0.143 | 0 |
| GCN1 | GCN1 | Q92616 | eIF-2-alpha kinase activator GCN1 | chr12 | GO:0019887 | Not Cancer Driver | No | 327 | 0.122 | 117 | 16 | 0.137 | 0 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0019887 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0019887 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
| GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0019887 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
| H2AFY | MACROH2A1 | O75367 | Core histone macro-H2A.1 | chr5 | GO:0019887 | Not Cancer Driver | No | 46 | 0.124 | 125 | 19 | 0.152 | 0 |
| HEXIM1 | HEXIM1 | O94992 | Protein HEXIM1 | chr17 | GO:0019887 | Not Cancer Driver | No | 40 | 0.111 | 352 | 40 | 0.114 | 0 |
| HEXIM2_ENST00000592695 | HEXIM2 | Q96MH2 | Protein HEXIM2 | chr17 | GO:0019887 | Not Cancer Driver | No | 35 | 0.122 | 286 | 35 | 0.122 | 0 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0019887 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0019887 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| HYAL2_ENST00000357750 | HYAL2 | Q12891 | Hyaluronidase-2 | chr3 | GO:0019887 | Not Cancer Driver | No | 52 | 0.11 | 8 | 1 | 0.125 | 0 |
| IBTK | IBTK | Q9P2D0 | Inhibitor of Bruton tyrosine kinase | chr6 | GO:0019887 | Not Cancer Driver | No | 146 | 0.108 | 364 | 39 | 0.107 | 0 |
| INCA1_ENST00000576820 | INCA1 | Q0VD86 | Protein INCA1 | chr17 | GO:0019887 | Not Cancer Driver | No | 18 | 0.076 | 195 | 14 | 0.072 | 0 |
| INKA1 | INKA1 | Q96EL1 | PAK4-inhibitor INKA1 | chr3 | GO:0019887 | Not Cancer Driver | No | 40 | 0.139 | 227 | 36 | 0.159 | 0 |
| INKA2 | INKA2 | Q9NTI7 | PAK4-inhibitor INKA2 | chr1 | GO:0019887 | Not Cancer Driver | No | 41 | 0.138 | 271 | 38 | 0.14 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0019887 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
| KIDINS220 | KIDINS220 | Q9ULH0 | Kinase D-interacting substrate of 220 kDa | chr2 | GO:0019887 | Not Cancer Driver | No | 245 | 0.138 | 683 | 113 | 0.165 | 0 |
| LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0019887 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
| MNAT1 | MNAT1 | P51948 | CDK-activating kinase assembly factor MAT1 | chr14 | GO:0019887 | Not Cancer Driver | No | 23 | 0.074 | 64 | 2 | 0.031 | 0 |
| NCAPG2_ENST00000356309 | NCAPG2 | Q86XI2 | Condensin-2 complex subunit G2 | chr7 | GO:0019887 | Not Cancer Driver | No | 113 | 0.099 | 72 | 8 | 0.111 | 3 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0019887 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NRG3_ENST00000404547 | NRG3 | P56975 | Pro-neuregulin-3, membrane-bound isoform | chr10 | GO:0019887 | Not Cancer Driver | No | 227 | 0.315 | 425 | 134 | 0.315 | 0 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0019887 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PKIA | PKIA | P61925 | cAMP-dependent protein kinase inhibitor alpha | chr8 | GO:0019887 | Not Cancer Driver | No | 18 | 0.237 | 76 | 18 | 0.237 | 0 |
| PKIB_ENST00000368448 | PKIB | Q9C010 | cAMP-dependent protein kinase inhibitor beta | chr6 | GO:0019887 | Not Cancer Driver | No | 13 | 0.167 | 78 | 13 | 0.167 | 0 |
| PKIG_ENST00000372891 | PKIG | Q9Y2B9 | cAMP-dependent protein kinase inhibitor gamma | chr20 | GO:0019887 | Not Cancer Driver | No | 15 | 0.197 | 76 | 15 | 0.197 | 0 |
| PPP1R1B | PPP1R1B | Q9UD71 | Protein phosphatase 1 regulatory subunit 1B | chr17 | GO:0019887 | Not Cancer Driver | No | 30 | 0.147 | 204 | 30 | 0.147 | 0 |
| PRKAG1_ENST00000548065 | PRKAG1 | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | chr12 | GO:0019887 | Not Cancer Driver | No | 35 | 0.106 | 25 | 2 | 0.08 | 0 |
| PRKAG2 | PRKAG2 | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | chr7 | GO:0019887 | Not Cancer Driver | No | 76 | 0.134 | 240 | 45 | 0.188 | 7 |
| PRKAG3_ENST00000529249 | PRKAG3 | Q9UGI9 | 5'-AMP-activated protein kinase subunit gamma-3 | chr2 | GO:0019887 | Not Cancer Driver | No | 74 | 0.151 | 144 | 25 | 0.174 | 0 |
| PRKAR1A_ENST00000536854 | PRKAR1A | P10644 | cAMP-dependent protein kinase type I-alpha regulatory subunit | chr17 | GO:0019887 | Census, Compendium | Yes | 39 | 0.102 | 66 | 11 | 0.167 | 17 |
| PRKAR1B_ENST00000403562 | PRKAR1B | P31321 | cAMP-dependent protein kinase type I-beta regulatory subunit | chr7 | GO:0019887 | Not Cancer Driver | No | 53 | 0.139 | 71 | 13 | 0.183 | 0 |
| PRKAR2A | PRKAR2A | P13861 | cAMP-dependent protein kinase type II-alpha regulatory subunit | chr3 | GO:0019887 | Not Cancer Driver | No | 37 | 0.092 | 149 | 13 | 0.087 | 0 |
| PRKAR2B | PRKAR2B | P31323 | cAMP-dependent protein kinase type II-beta regulatory subunit | chr7 | GO:0019887 | Not Cancer Driver | No | 60 | 0.144 | 125 | 4 | 0.032 | 0 |
| RAC2 | RAC2 | P15153 | Ras-related C3 botulinum toxin substrate 2 | chr22 | GO:0019887 | Not Cancer Driver | No | 31 | 0.161 | 0 | 0 | 0.0 | 2 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0019887 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0019887 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0019887 | Not Cancer Driver | No | 27 | 0.109 | 75 | 9 | 0.12 | 0 |
| SPRED1 | SPRED1 | Q7Z699 | Sprouty-related, EVH1 domain-containing protein 1 | chr15 | GO:0019887 | Not Cancer Driver | No | 71 | 0.16 | 194 | 35 | 0.18 | 2 |
| SPRED2 | SPRED2 | Q7Z698 | Sprouty-related, EVH1 domain-containing protein 2 | chr2 | GO:0019887 | Not Cancer Driver | No | 73 | 0.175 | 228 | 43 | 0.189 | 0 |
| SPRY2 | SPRY2 | O43597 | Protein sprouty homolog 2 | chr13 | GO:0019887 | Not Cancer Driver | No | 46 | 0.146 | 169 | 29 | 0.172 | 1 |
| TAL1 | TAL1 | P17542 | T-cell acute lymphocytic leukemia protein 1 | chr1 | GO:0019887 | Census | Yes | 54 | 0.163 | 305 | 53 | 0.174 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | GO:0019887 | Not Cancer Driver | No | 26 | 0.105 | 77 | 9 | 0.117 | 2 |