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Total number of protein in "GO:0080135" GO term:  487

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0080135 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0080135 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0080135 Not Cancer Driver No 46 0.126 248 31 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0080135 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0080135 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0080135 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0080135 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0080135 Not Cancer Driver No 51 0.129 6 2 0.333 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0080135 Not Cancer Driver No 419 0.335 215 38 0.177 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0080135 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0080135 Not Cancer Driver No 23 0.131 20 2 0.1 0
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0080135 Not Cancer Driver No 36 0.118 87 9 0.103 0
AIFM2_ENST00000307864 AIFM2 Q9BRQ8 Ferroptosis suppressor protein 1 chr10 GO:0080135 Not Cancer Driver No 47 0.126 8 0 0.0 0
AJUBA AJUBA Q96IF1 LIM domain-containing protein ajuba chr14 GO:0080135 Compendium Yes 45 0.084 307 13 0.042 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0080135 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 GO:0080135 Census, Compendium Yes 92 0.192 131 24 0.183 3
ALOX5 ALOX5 P09917 Polyunsaturated fatty acid 5-lipoxygenase chr10 GO:0080135 Not Cancer Driver No 129 0.191 16 2 0.125 0
AMBP AMBP P02760 Protein AMBP chr9 GO:0080135 Not Cancer Driver No 57 0.162 61 15 0.246 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0080135 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0080135 Not Cancer Driver No 52 0.163 83 13 0.157 0
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0080135 Not Cancer Driver No 23 0.085 0 0 0.0 0
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0080135 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0080135 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0080135 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0080135 Not Cancer Driver No 71 0.113 332 40 0.12 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0080135 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0080135 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0080135 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0080135 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0080135 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0080135 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0080135 Not Cancer Driver No 46 0.127 181 24 0.133 0
AUNIP_ENST00000374298 AUNIP Q9H7T9 Aurora kinase A and ninein-interacting protein chr1 GO:0080135 Not Cancer Driver No 23 0.064 341 21 0.062 0
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0080135 Census, Compendium Yes 114 0.135 547 77 0.141 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0080135 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0080135 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0080135 Not Cancer Driver No 37 0.083 63 7 0.111 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0080135 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0080135 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0080135 Census Yes 30 0.156 39 2 0.051 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0080135 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0080135 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0080135 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0080135 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0080135 Census, Compendium Yes 134 0.19 328 67 0.204 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0080135 Not Cancer Driver No 81 0.207 0 0 0.0 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0080135 Not Cancer Driver No 56 0.124 30 1 0.033 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0080135 Not Cancer Driver No 23 0.118 74 9 0.122 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0080135 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0080135 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0080135 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0080135 Census, Compendium Yes 66 0.124 21 0 0.0 8
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0080135 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0080135 Not Cancer Driver No 189 0.153 934 147 0.157 0
C12orf49 SPRING1 Q9H741 SREBP regulating gene protein chr12 GO:0080135 Not Cancer Driver No 26 0.127 0 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0080135 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0080135 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0080135 Not Cancer Driver No 102 0.111 528 62 0.117 0
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0080135 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0080135 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD44 CD44 P16070 CD44 antigen chr11 GO:0080135 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0080135 Census Yes 31 0.105 185 20 0.108 0
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:0080135 Census Yes 40 0.123 24 3 0.125 1
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0080135 Not Cancer Driver No 17 0.102 44 3 0.068 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0080135 Not Cancer Driver No 38 0.1 36 4 0.111 0
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0080135 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 GO:0080135 Not Cancer Driver No 24 0.159 114 21 0.184 1
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0080135 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 GO:0080135 Not Cancer Driver No 47 0.142 119 17 0.143 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0080135 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0080135 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0080135 Not Cancer Driver No 41 0.205 34 5 0.147 0
COPS3 COPS3 Q9UNS2 COP9 signalosome complex subunit 3 chr17 GO:0080135 Not Cancer Driver No 55 0.13 67 10 0.149 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0080135 Not Cancer Driver No 36 0.108 32 7 0.219 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0080135 Not Cancer Driver No 85 0.177 37 7 0.189 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0080135 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0080135 Census Yes 68 0.131 372 50 0.134 0
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0080135 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0080135 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0080135 Not Cancer Driver No 76 0.13 91 5 0.055 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0080135 Census, Compendium Yes 415 0.531 288 301 1.045 14
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:0080135 Not Cancer Driver No 64 0.084 102 2 0.02 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0080135 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYLD CYLD Q9NQC7 Ubiquitin carboxyl-terminal hydrolase CYLD chr16 GO:0080135 Census, Compendium Yes 116 0.121 213 31 0.146 3
CYREN CYREN Q9BWK5 Cell cycle regulator of non-homologous end joining chr7 GO:0080135 Not Cancer Driver No 24 0.153 128 19 0.148 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0080135 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0080135 Not Cancer Driver No 163 0.195 598 127 0.212 1
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0080135 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:0080135 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0080135 Census Yes 29 0.172 160 27 0.169 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0080135 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0080135 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX39B_ENST00000458640 DDX39B Q13838 Spliceosome RNA helicase DDX39B chr6 GO:0080135 Not Cancer Driver No 49 0.114 34 8 0.235 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0080135 Census Yes 74 0.121 225 23 0.102 0
DEK DEK P35659 Protein DEK chr6 GO:0080135 Census Yes 47 0.125 297 41 0.138 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0080135 Not Cancer Driver No 16 0.086 12 2 0.167 2
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0080135 Not Cancer Driver No 120 0.133 460 67 0.146 0
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0080135 Not Cancer Driver No 49 0.105 269 28 0.104 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0080135 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0080135 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJB6 DNAJB6 O75190 DnaJ homolog subfamily B member 6 chr7 GO:0080135 Not Cancer Driver No 33 0.101 198 17 0.086 3
DNAJB9 DNAJB9 Q9UBS3 DnaJ homolog subfamily B member 9 chr7 GO:0080135 Not Cancer Driver No 30 0.135 107 15 0.14 0
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 GO:0080135 Not Cancer Driver No 67 0.108 425 48 0.113 0
DNAJC7 DNAJC7 Q99615 DnaJ homolog subfamily C member 7 chr17 GO:0080135 Not Cancer Driver No 41 0.083 102 9 0.088 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0080135 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0080135 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0080135 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0080135 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0080135 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0080135 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0080135 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0080135 Not Cancer Driver No 87 0.148 193 20 0.104 0
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:0080135 Not Cancer Driver No 27 0.155 11 1 0.091 0
EFHD1 EFHD1 Q9BUP0 EF-hand domain-containing protein D1 chr2 GO:0080135 Not Cancer Driver No 30 0.126 94 7 0.074 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:0080135 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0080135 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0080135 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ELL3 ELL3 Q9HB65 RNA polymerase II elongation factor ELL3 chr15 GO:0080135 Not Cancer Driver No 50 0.126 186 13 0.07 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0080135 Not Cancer Driver No 25 0.095 109 15 0.138 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0080135 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0080135 Not Cancer Driver No 51 0.118 21 2 0.095 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0080135 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0080135 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 GO:0080135 Not Cancer Driver No 104 0.124 515 68 0.132 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:0080135 Not Cancer Driver No 95 0.118 583 67 0.115 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0080135 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPO EPO P01588 Erythropoietin chr7 GO:0080135 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0080135 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0080135 Census Yes 120 0.131 225 27 0.12 15
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0080135 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0080135 Not Cancer Driver No 25 0.063 53 8 0.151 7
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0080135 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERP29 ERP29 P30040 Endoplasmic reticulum resident protein 29 chr12 GO:0080135 Not Cancer Driver No 29 0.111 34 5 0.147 0
ETAA1 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 GO:0080135 Not Cancer Driver No 101 0.109 735 75 0.102 0
EZR EZR P15311 Ezrin chr6 GO:0080135 Census Yes 66 0.113 295 35 0.119 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0080135 Not Cancer Driver No 55 0.139 7 2 0.286 0
FAM168A FAM168A Q92567 Protein FAM168A chr11 GO:0080135 Not Cancer Driver No 17 0.07 139 11 0.079 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0080135 Not Cancer Driver No 109 0.127 24 5 0.208 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0080135 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBLN5 FBLN5 Q9UBX5 Fibulin-5 chr14 GO:0080135 Not Cancer Driver No 77 0.172 11 2 0.182 16
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0080135 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0080135 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0080135 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0080135 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0080135 Census Yes 51 0.165 99 30 0.303 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0080135 Not Cancer Driver No 69 0.11 33 3 0.091 0
FICD FICD Q9BVA6 Protein adenylyltransferase FICD chr12 GO:0080135 Not Cancer Driver No 46 0.1 42 3 0.071 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0080135 Not Cancer Driver No 10 0.093 58 4 0.069 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:0080135 Not Cancer Driver No 51 0.111 0 0 0.0 10
FLNA FLNA P21333 Filamin-A chrX GO:0080135 Census Yes 416 0.157 1456 214 0.147 28
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0080135 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0080135 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0080135 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0080135 Census, Compendium Yes 70 0.104 595 68 0.114 0
FUS FUS P35637 RNA-binding protein FUS chr16 GO:0080135 Census Yes 51 0.097 524 51 0.097 20
FUT8_ENST00000394586 FUT8 Q9BYC5 Alpha-(1,6)-fucosyltransferase chr14 GO:0080135 Not Cancer Driver No 79 0.137 80 19 0.237 1
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0080135 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD1 FZD1 Q9UP38 Frizzled-1 chr7 GO:0080135 Not Cancer Driver No 78 0.121 133 2 0.015 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0080135 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:0080135 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0080135 Not Cancer Driver No 13 0.082 20 2 0.1 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0080135 Not Cancer Driver No 48 0.109 301 34 0.113 18
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0080135 Not Cancer Driver No 20 0.08 99 5 0.051 38
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0080135 Not Cancer Driver No 91 0.2 225 46 0.204 14
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0080135 Not Cancer Driver No 10 0.049 97 4 0.041 1
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 GO:0080135 Not Cancer Driver No 124 0.202 200 42 0.21 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0080135 Not Cancer Driver No 62 0.129 81 8 0.099 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0080135 Not Cancer Driver No 29 0.089 319 26 0.082 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0080135 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:0080135 Not Cancer Driver No 39 0.105 150 15 0.1 0
GRN GRN P28799 Progranulin chr17 GO:0080135 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0080135 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0080135 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0080135 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0080135 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0080135 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0080135 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0080135 Not Cancer Driver No 59 0.088 622 57 0.092 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0080135 Census Yes 38 0.097 248 17 0.069 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0080135 Compendium Yes 233 0.32 43 16 0.372 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:0080135 Not Cancer Driver No 24 0.033 361 6 0.017 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0080135 Census Yes 118 0.143 435 51 0.117 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0080135 Not Cancer Driver No 128 0.105 559 51 0.091 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0080135 Not Cancer Driver No 94 0.278 85 22 0.259 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0080135 Census Yes 12 0.11 109 12 0.11 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0080135 Not Cancer Driver No 25 0.116 203 20 0.099 0
HNRNPK_ENST00000351839 HNRNPK P61978 Heterogeneous nuclear ribonucleoprotein K chr9 GO:0080135 Not Cancer Driver No 75 0.162 302 59 0.195 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0080135 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0080135 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0080135 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0080135 Not Cancer Driver No 10 0.049 118 8 0.068 20
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0080135 Compendium Yes 44 0.096 127 9 0.071 2
HYOU1 HYOU1 Q9Y4L1 Hypoxia up-regulated protein 1 chr11 GO:0080135 Not Cancer Driver No 132 0.132 373 47 0.126 0
IER5 IER5 Q5VY09 Immediate early response gene 5 protein chr1 GO:0080135 Not Cancer Driver No 20 0.061 271 15 0.055 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:0080135 Not Cancer Driver No 51 0.15 193 28 0.145 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0080135 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0080135 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0080135 Not Cancer Driver No 39 0.145 16 3 0.188 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0080135 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 GO:0080135 Not Cancer Driver No 44 0.105 292 32 0.11 1
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0080135 Not Cancer Driver No 31 0.124 108 15 0.139 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0080135 Not Cancer Driver No 138 0.122 394 45 0.114 0
INS INS P01308 Insulin chr11 GO:0080135 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0080135 Not Cancer Driver No 37 0.134 43 1 0.023 0
INSIG2 INSIG2 Q9Y5U4 Insulin-induced gene 2 protein chr2 GO:0080135 Not Cancer Driver No 47 0.209 11 3 0.273 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0080135 Not Cancer Driver No 95 0.105 335 42 0.125 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0080135 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0080135 Census Yes 97 0.159 327 47 0.144 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0080135 Not Cancer Driver No 109 0.256 40 10 0.25 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0080135 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0080135 Not Cancer Driver No 78 0.149 215 33 0.153 0
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0080135 Not Cancer Driver No 68 0.313 121 43 0.355 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0080135 Not Cancer Driver No 204 0.19 492 85 0.173 0
KLHL31 KLHL31 Q9H511 Kelch-like protein 31 chr6 GO:0080135 Not Cancer Driver No 69 0.109 32 1 0.031 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0080135 Not Cancer Driver No 65 0.25 76 15 0.197 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0080135 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0080135 Not Cancer Driver No 37 0.08 142 9 0.063 0
KREMEN1_ENST00000407188 KREMEN1 Q96MU8 Kremen protein 1 chr22 GO:0080135 Not Cancer Driver No 68 0.144 73 7 0.096 1
LANCL1_ENST00000450366 LANCL1 O43813 Glutathione S-transferase LANCL1 chr2 GO:0080135 Not Cancer Driver No 45 0.113 10 0 0.0 0
LEP LEP P41159 Leptin chr7 GO:0080135 Not Cancer Driver No 29 0.174 0 0 0.0 2
LETM1 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 GO:0080135 Not Cancer Driver No 77 0.104 286 28 0.098 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0080135 Not Cancer Driver No 54 0.152 65 16 0.246 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0080135 Not Cancer Driver No 54 0.111 1 0 0.0 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0080135 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0080135 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0080135 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0080135 Not Cancer Driver No 79 0.252 103 18 0.175 0
MANF MANF P55145 Mesencephalic astrocyte-derived neurotrophic factor chr3 GO:0080135 Not Cancer Driver No 14 0.077 1 0 0.0 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0080135 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0080135 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0080135 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0080135 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0080135 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0080135 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0080135 Not Cancer Driver No 79 0.111 444 40 0.09 1
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0080135 Not Cancer Driver No 70 0.134 173 25 0.145 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0080135 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0080135 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0080135 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0080135 Not Cancer Driver No 40 0.1 179 10 0.056 0
MBTD1_ENST00000415868 MBTD1 Q05BQ5 MBT domain-containing protein 1 chr17 GO:0080135 Not Cancer Driver No 66 0.105 119 8 0.067 0
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0080135 Not Cancer Driver No 63 0.121 16 4 0.25 9
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0080135 Not Cancer Driver No 30 0.086 203 21 0.103 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0080135 Census, Compendium Yes 56 0.114 297 37 0.125 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0080135 Not Cancer Driver No 22 0.115 171 21 0.123 0
MEAK7 MEAK7 Q6P9B6 MTOR-associated protein MEAK7 chr16 GO:0080135 Not Cancer Driver No 56 0.123 182 24 0.132 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:0080135 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEN1 MEN1 O00255 Menin chr11 GO:0080135 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0080135 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0080135 Not Cancer Driver No 95 0.09 98 9 0.092 0
MICU1 MICU1 Q9BPX6 Calcium uptake protein 1, mitochondrial chr10 GO:0080135 Not Cancer Driver No 50 0.105 97 18 0.186 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0080135 Not Cancer Driver No 4 0.035 0 0 0.0 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0080135 Not Cancer Driver No 113 0.085 740 56 0.076 0
MMP3 MMP3 P08254 Stromelysin-1 chr11 GO:0080135 Not Cancer Driver No 99 0.208 66 14 0.212 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0080135 Not Cancer Driver No 73 0.071 11 0 0.0 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:0080135 Not Cancer Driver No 43 0.119 163 17 0.104 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0080135 Not Cancer Driver No 44 0.153 136 21 0.154 0
MRGBP MRGBP Q9NV56 MRG/MORF4L-binding protein chr20 GO:0080135 Not Cancer Driver No 27 0.132 147 23 0.156 0
MRNIP MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0080135 Not Cancer Driver No 44 0.128 268 35 0.131 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0080135 Not Cancer Driver No 39 0.129 197 16 0.081 7
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0080135 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0080135 Census Yes 40 0.032 1050 19 0.018 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0080135 Census, Compendium Yes 80 0.182 299 46 0.154 0
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0080135 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0080135 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0080135 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0080135 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCOA7_ENST00000368357 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 GO:0080135 Not Cancer Driver No 110 0.117 538 63 0.117 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0080135 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0080135 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 GO:0080135 Not Cancer Driver No 78 0.093 492 49 0.1 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:0080135 Not Cancer Driver No 31 0.099 36 0 0.0 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0080135 Census, Compendium Yes 228 0.377 402 62 0.154 4
NME5 NME5 P56597 Nucleoside diphosphate kinase homolog 5 chr5 GO:0080135 Not Cancer Driver No 17 0.08 6 0 0.0 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0080135 Not Cancer Driver No 20 0.096 179 17 0.095 2
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0080135 Census, Compendium Yes 101 0.214 349 64 0.183 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0080135 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0080135 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0080135 Not Cancer Driver No 32 0.212 71 14 0.197 1
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0080135 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0080135 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0080135 Census Yes 83 0.133 298 37 0.124 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0080135 Census, Compendium Yes 191 0.14 552 76 0.138 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0080135 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUDT16L1 NUDT16L1 Q9BRJ7 Tudor-interacting repair regulator protein chr16 GO:0080135 Not Cancer Driver No 16 0.076 6 0 0.0 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0080135 Not Cancer Driver No 10 0.122 82 10 0.122 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0080135 Not Cancer Driver No 37 0.107 71 12 0.169 0
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0080135 Not Cancer Driver No 46 0.309 48 14 0.292 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0080135 Not Cancer Driver No 114 0.119 131 17 0.13 60
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0080135 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0080135 Not Cancer Driver No 107 0.268 58 27 0.466 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0080135 Not Cancer Driver No 126 0.144 544 76 0.14 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0080135 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0080135 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX GO:0080135 Not Cancer Driver No 20 0.196 102 20 0.196 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0080135 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0080135 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0080135 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0080135 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0080135 Not Cancer Driver No 35 0.103 327 33 0.101 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0080135 Not Cancer Driver No 23 0.071 92 6 0.065 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0080135 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0080135 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0080135 Not Cancer Driver No 32 0.113 238 23 0.097 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0080135 Census Yes 160 0.124 948 116 0.122 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:0080135 Not Cancer Driver No 134 0.078 744 29 0.039 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0080135 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0080135 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0080135 Census, Compendium Yes 154 0.213 268 61 0.228 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0080135 Not Cancer Driver No 57 0.098 99 13 0.131 23
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0080135 Not Cancer Driver No 80 0.113 598 66 0.11 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0080135 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0080135 Not Cancer Driver No 92 0.134 178 21 0.118 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0080135 Not Cancer Driver No 2 0.037 23 1 0.043 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0080135 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPLA8 PNPLA8 Q9NP80 Calcium-independent phospholipase A2-gamma chr7 GO:0080135 Not Cancer Driver No 94 0.12 140 18 0.129 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0080135 Not Cancer Driver No 86 0.11 115 10 0.087 2
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 GO:0080135 Not Cancer Driver No 157 0.111 746 78 0.105 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0080135 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0080135 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0080135 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0080135 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0080135 Not Cancer Driver No 72 0.101 415 45 0.108 1
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0080135 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0080135 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0080135 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0080135 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0080135 Census, Compendium Yes 69 0.282 205 49 0.239 1
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0080135 Not Cancer Driver No 20 0.088 53 5 0.094 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0080135 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0080135 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTN PTN P21246 Pleiotrophin chr7 GO:0080135 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0080135 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0080135 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0080135 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0080135 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0080135 Not Cancer Driver No 250 0.128 829 111 0.134 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0080135 Not Cancer Driver No 23 0.128 30 9 0.3 0
PYCR1_ENST00000329875 PYCR1 P32322 Pyrroline-5-carboxylate reductase 1, mitochondrial chr17 GO:0080135 Not Cancer Driver No 31 0.097 67 10 0.149 9
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0080135 Not Cancer Driver No 174 0.354 291 99 0.34 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0080135 Not Cancer Driver No 101 0.13 106 16 0.151 4
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0080135 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0080135 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0080135 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0080135 Not Cancer Driver No 34 0.087 135 7 0.052 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0080135 Not Cancer Driver No 96 0.12 191 12 0.063 1
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0080135 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBL1 RBL1 P28749 Retinoblastoma-like protein 1 chr20 GO:0080135 Not Cancer Driver No 140 0.131 335 41 0.122 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:0080135 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:0080135 Not Cancer Driver No 39 0.129 259 37 0.143 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0080135 Not Cancer Driver No 142 0.129 868 113 0.13 4
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:0080135 Census Yes 68 0.088 318 30 0.094 1
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0080135 Not Cancer Driver No 63 0.14 105 13 0.124 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0080135 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0080135 Compendium Yes 82 0.122 277 39 0.141 4
RNASEH2B RNASEH2B Q5TBB1 Ribonuclease H2 subunit B chr13 GO:0080135 Not Cancer Driver No 34 0.109 84 9 0.107 14
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0080135 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0080135 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0080135 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0080135 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0080135 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0080135 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0080135 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0080135 Not Cancer Driver No 22 0.091 48 4 0.083 0
RSL1D1 RSL1D1 O76021 Ribosomal L1 domain-containing protein 1 chr16 GO:0080135 Not Cancer Driver No 61 0.124 275 33 0.12 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0080135 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0080135 Not Cancer Driver No 38 0.08 148 17 0.115 5
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0080135 Not Cancer Driver No 56 0.127 142 12 0.085 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0080135 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0080135 Not Cancer Driver No 62 0.134 100 13 0.13 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0080135 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCARF1 SCARF1 Q14162 Scavenger receptor class F member 1 chr17 GO:0080135 Not Cancer Driver No 90 0.108 340 61 0.179 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0080135 Not Cancer Driver No 7 0.037 122 6 0.049 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0080135 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0080135 Not Cancer Driver No 142 0.364 47 28 0.596 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0080135 Not Cancer Driver No 62 0.091 154 12 0.078 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0080135 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0080135 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0080135 Not Cancer Driver No 47 0.159 1 0 0.0 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0080135 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0080135 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0080135 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0080135 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0080135 Not Cancer Driver No 3 0.012 81 1 0.012 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0080135 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0080135 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0080135 Not Cancer Driver No 48 0.12 163 15 0.092 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0080135 Not Cancer Driver No 77 0.113 356 32 0.09 0
SLC25A23 SLC25A23 Q9BV35 Calcium-binding mitochondrial carrier protein SCaMC-3 chr19 GO:0080135 Not Cancer Driver No 63 0.135 74 8 0.108 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0080135 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 GO:0080135 Not Cancer Driver No 60 0.119 9 1 0.111 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0080135 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0080135 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0080135 Not Cancer Driver No 112 0.095 725 76 0.105 0
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 GO:0080135 Not Cancer Driver No 240 0.12 342 45 0.132 45
SMYD2 SMYD2 Q9NRG4 N-lysine methyltransferase SMYD2 chr1 GO:0080135 Not Cancer Driver No 42 0.097 12 0 0.0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0080135 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0080135 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0080135 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0080135 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0080135 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0080135 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0080135 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0080135 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0080135 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0080135 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0080135 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0080135 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0080135 Not Cancer Driver No 73 0.175 228 43 0.189 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0080135 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0080135 Not Cancer Driver No 62 0.149 119 18 0.151 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0080135 Not Cancer Driver No 64 0.117 182 19 0.104 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0080135 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0080135 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0080135 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAF9B TAF9B Q9HBM6 Transcription initiation factor TFIID subunit 9B chrX GO:0080135 Not Cancer Driver No 48 0.191 189 34 0.18 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0080135 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0080135 Not Cancer Driver No 74 0.104 401 36 0.09 1
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0080135 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0080135 Census Yes 110 0.097 212 16 0.075 31
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0080135 Not Cancer Driver No 87 0.104 331 39 0.118 0
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0080135 Not Cancer Driver No 55 0.084 280 26 0.093 0
THOC5_ENST00000397872 THOC5 Q13769 THO complex subunit 5 homolog chr22 GO:0080135 Not Cancer Driver No 88 0.129 173 25 0.145 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0080135 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0080135 Not Cancer Driver No 154 0.127 367 51 0.139 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0080135 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0080135 Not Cancer Driver No 99 0.124 1 0 0.0 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0080135 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0080135 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0080135 Not Cancer Driver No 49 0.102 22 8 0.364 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0080135 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 GO:0080135 Not Cancer Driver No 24 0.097 6 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0080135 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNR TNR Q92752 Tenascin-R chr1 GO:0080135 Not Cancer Driver No 496 0.365 358 128 0.358 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0080135 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPT1_ENST00000530705 TPT1 P13693 Translationally-controlled tumor protein chr13 GO:0080135 Not Cancer Driver No 17 0.099 43 6 0.14 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:0080135 Not Cancer Driver No 74 0.105 110 11 0.1 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0080135 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0080135 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0080135 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0080135 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0080135 Census, Compendium Yes 554 0.144 402 59 0.147 8
TSC1 TSC1 Q92574 Hamartin chr9 GO:0080135 Census, Compendium Yes 135 0.116 732 78 0.107 11
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0080135 Not Cancer Driver No 23 0.114 132 11 0.083 7
TXN TXN P10599 Thioredoxin chr9 GO:0080135 Not Cancer Driver No 6 0.057 0 0 0.0 0
TXNDC12 TXNDC12 O95881 Thioredoxin domain-containing protein 12 chr1 GO:0080135 Not Cancer Driver No 21 0.122 44 6 0.136 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0080135 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0080135 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0080135 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0080135 Not Cancer Driver No 82 0.131 581 79 0.136 8
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0080135 Not Cancer Driver No 35 0.118 271 33 0.122 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0080135 Not Cancer Driver No 109 0.137 141 24 0.17 0
ULK4 ULK4 Q96C45 Serine/threonine-protein kinase ULK4 chr3 GO:0080135 Not Cancer Driver No 162 0.127 180 33 0.183 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0080135 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0080135 Not Cancer Driver No 59 0.119 86 6 0.07 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0080135 Not Cancer Driver No 161 0.122 539 68 0.126 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0080135 Not Cancer Driver No 135 0.128 354 55 0.155 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0080135 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP51 USP51 Q70EK9 Ubiquitin carboxyl-terminal hydrolase 51 chrX GO:0080135 Not Cancer Driver No 100 0.141 246 34 0.138 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0080135 Not Cancer Driver No 39 0.107 215 18 0.084 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0080135 Not Cancer Driver No 27 0.116 41 7 0.171 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0080135 Not Cancer Driver No 88 0.172 20 5 0.25 0
VPS13C_ENST00000261517 VPS13C Q709C8 Intermembrane lipid transfer protein VPS13C chr15 GO:0080135 Not Cancer Driver No 446 0.119 433 51 0.118 1
VPS72 VPS72 Q15906 Vacuolar protein sorting-associated protein 72 homolog chr1 GO:0080135 Not Cancer Driver No 43 0.118 329 37 0.112 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0080135 Census, Compendium Yes 75 0.149 400 55 0.138 30
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0080135 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 GO:0080135 Not Cancer Driver No 60 0.096 288 33 0.115 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0080135 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0080135 Not Cancer Driver No 29 0.078 25 0 0.0 8
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0080135 Not Cancer Driver No 66 0.12 232 29 0.125 4
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0080135 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0080135 Not Cancer Driver No 279 0.209 134 24 0.179 1
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0080135 Not Cancer Driver No 85 0.134 426 53 0.124 1
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0080135 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0080135 Not Cancer Driver No 49 0.132 359 47 0.131 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 GO:0080135 Not Cancer Driver No 23 0.101 17 1 0.059 0
YJU2 YJU2 Q9BW85 Splicing factor YJU2 chr19 GO:0080135 Not Cancer Driver No 29 0.09 233 13 0.056 0
YPEL3_ENST00000566595 YPEL3 P61236 Protein yippee-like 3 chr16 GO:0080135 Not Cancer Driver No 13 0.109 0 0 0.0 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0080135 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0080135 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCWPW1 ZCWPW1 Q9H0M4 Zinc finger CW-type PWWP domain protein 1 chr7 GO:0080135 Not Cancer Driver No 90 0.139 456 61 0.134 0
ZKSCAN3_ENST00000252211 ZKSCAN3 Q9BRR0 Zinc finger protein with KRAB and SCAN domains 3 chr6 GO:0080135 Not Cancer Driver No 70 0.13 267 30 0.112 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0080135 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0080135 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF277 ZNF277 Q9NRM2 Zinc finger protein 277 chr7 GO:0080135 Not Cancer Driver No 59 0.131 79 15 0.19 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0080135 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0080135 Not Cancer Driver No 114 0.201 91 19 0.209 0