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Total number of protein in "GO:0060284" GO term:  405

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0060284 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0060284 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0060284 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0060284 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0060284 Not Cancer Driver No 51 0.129 6 2 0.333 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0060284 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADGRA2 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0060284 Not Cancer Driver No 140 0.105 417 32 0.077 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0060284 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0060284 Not Cancer Driver No 130 0.118 615 66 0.107 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0060284 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0060284 Not Cancer Driver No 104 0.127 146 26 0.178 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0060284 Not Cancer Driver No 145 0.138 239 33 0.138 0
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 GO:0060284 Not Cancer Driver No 24 0.079 257 24 0.093 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0060284 Not Cancer Driver No 28 0.105 131 8 0.061 3
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0060284 Not Cancer Driver No 70 0.105 149 14 0.094 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0060284 Not Cancer Driver No 125 0.132 464 76 0.164 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0060284 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0060284 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 GO:0060284 Not Cancer Driver No 40 0.133 49 8 0.163 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0060284 Not Cancer Driver No 2 0.01 166 1 0.006 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0060284 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0060284 Not Cancer Driver No 554 0.159 424 67 0.158 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0060284 Not Cancer Driver No 63 0.178 327 55 0.168 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0060284 Not Cancer Driver No 36 0.089 178 21 0.118 0
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0060284 Census, Compendium Yes 114 0.135 547 77 0.141 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0060284 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0060284 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0060284 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0060284 Census, Compendium Yes 210 0.251 677 171 0.253 3
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0060284 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0060284 Not Cancer Driver No 47 0.19 79 19 0.241 1
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0060284 Not Cancer Driver No 88 0.161 267 38 0.142 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0060284 Not Cancer Driver No 65 0.11 456 42 0.092 5
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0060284 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0060284 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0060284 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0060284 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0060284 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0060284 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0060284 Not Cancer Driver No 273 0.359 36 17 0.472 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0060284 Not Cancer Driver No 14 0.05 103 6 0.058 2
CALR CALR P27797 Calreticulin chr19 GO:0060284 Census Yes 45 0.108 245 31 0.127 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0060284 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAPRIN1_ENST00000532820 CAPRIN1 Q14444 Caprin-1 chr11 GO:0060284 Not Cancer Driver No 84 0.118 603 72 0.119 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0060284 Not Cancer Driver No 171 0.125 537 87 0.162 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0060284 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0060284 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCL11 CCL11 P51671 Eotaxin chr17 GO:0060284 Not Cancer Driver No 18 0.186 14 3 0.214 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0060284 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0060284 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0060284 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0060284 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0060284 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0060284 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0060284 Not Cancer Driver No 165 0.172 685 120 0.175 18
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0060284 Not Cancer Driver No 15 0.109 67 3 0.045 0
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0060284 Not Cancer Driver No 38 0.1 36 4 0.111 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0060284 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0060284 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLDN18 CLDN18 P56856 Claudin-18 chr3 GO:0060284 Not Cancer Driver No 44 0.169 21 5 0.238 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0060284 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0060284 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0060284 Not Cancer Driver No 83 0.098 458 38 0.083 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0060284 Not Cancer Driver No 61 0.129 84 13 0.155 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0060284 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0060284 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0060284 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 GO:0060284 Not Cancer Driver No 75 0.133 397 46 0.116 0
CTDSP1 CTDSP1 Q9GZU7 Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 chr2 GO:0060284 Not Cancer Driver No 34 0.13 46 2 0.043 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0060284 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0060284 Census, Compendium Yes 415 0.531 288 301 1.045 14
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0060284 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0060284 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0060284 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0060284 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0060284 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0060284 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0060284 Not Cancer Driver No 46 0.037 96 0 0.0 0
DAAM2 DAAM2 Q86T65 Disheveled-associated activator of morphogenesis 2 chr6 GO:0060284 Not Cancer Driver No 183 0.171 272 55 0.202 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0060284 Not Cancer Driver No 200 0.34 393 143 0.364 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0060284 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0060284 Not Cancer Driver No 102 0.114 485 61 0.126 4
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0060284 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0060284 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0060284 Census, Compendium Yes 530 0.366 631 215 0.341 2
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0060284 Not Cancer Driver No 113 0.218 19 4 0.211 2
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0060284 Not Cancer Driver No 159 0.158 222 39 0.176 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0060284 Census, Compendium Yes 264 0.137 362 45 0.124 4
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0060284 Not Cancer Driver No 181 0.115 375 49 0.131 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0060284 Not Cancer Driver No 132 0.155 514 82 0.16 0
DLL3 DLL3 Q9NYJ7 Delta-like protein 3 chr19 GO:0060284 Not Cancer Driver No 73 0.118 119 10 0.084 1
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0060284 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0060284 Not Cancer Driver No 46 0.14 262 38 0.145 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0060284 Not Cancer Driver No 25 0.046 325 19 0.058 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0060284 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJB11_ENST00000265028 DNAJB11 Q9UBS4 DnaJ homolog subfamily B member 11 chr3 GO:0060284 Not Cancer Driver No 52 0.145 141 21 0.149 2
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0060284 Census Yes 138 0.159 270 43 0.159 22
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0060284 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0060284 Not Cancer Driver No 278 0.149 330 45 0.136 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0060284 Not Cancer Driver No 61 0.175 249 48 0.193 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0060284 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0060284 Not Cancer Driver No 88 0.22 45 17 0.378 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0060284 Not Cancer Driver No 652 0.324 603 201 0.333 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0060284 Not Cancer Driver No 81 0.168 135 24 0.178 0
DYNLT1 DYNLT1 P63172 Dynein light chain Tctex-type 1 chr6 GO:0060284 Not Cancer Driver No 7 0.062 1 0 0.0 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0060284 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0060284 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0060284 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0060284 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0060284 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0060284 Compendium Yes 90 0.189 352 59 0.168 11
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0060284 Not Cancer Driver No 104 0.115 382 43 0.113 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0060284 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0060284 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0060284 Not Cancer Driver No 186 0.176 119 17 0.143 7
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0060284 Census, Compendium Yes 120 0.161 284 44 0.155 11
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0060284 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0060284 Not Cancer Driver No 115 0.185 97 25 0.258 10
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0060284 Not Cancer Driver No 99 0.133 206 20 0.097 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0060284 Compendium Yes 122 0.174 22 3 0.136 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0060284 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBXO22 FBXO22 Q8NEZ5 F-box only protein 22 chr15 GO:0060284 Not Cancer Driver No 65 0.161 15 3 0.2 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0060284 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0060284 Census, Compendium Yes 322 0.455 230 38 0.165 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0060284 Not Cancer Driver No 68 0.114 120 4 0.033 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0060284 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0060284 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0060284 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0060284 Not Cancer Driver No 70 0.286 96 33 0.344 2
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0060284 Not Cancer Driver No 81 0.179 53 8 0.151 8
FLNA FLNA P21333 Filamin-A chrX GO:0060284 Census Yes 416 0.157 1456 214 0.147 28
FN1 FN1 P02751 Fibronectin chr2 GO:0060284 Compendium Yes 394 0.159 1243 185 0.149 8
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0060284 Not Cancer Driver No 132 0.27 322 79 0.245 2
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0060284 Not Cancer Driver No 58 0.178 31 6 0.194 1
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0060284 Not Cancer Driver No 134 0.159 96 12 0.125 0
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0060284 Not Cancer Driver No 64 0.096 141 13 0.092 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0060284 Not Cancer Driver No 92 0.155 166 27 0.163 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0060284 Not Cancer Driver No 69 0.154 34 6 0.176 2
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0060284 Not Cancer Driver No 65 0.15 288 42 0.146 62
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0060284 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0060284 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0060284 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GORASP1 GORASP1 Q9BQQ3 Golgi reassembly-stacking protein 1 chr3 GO:0060284 Not Cancer Driver No 49 0.111 293 32 0.109 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0060284 Not Cancer Driver No 62 0.129 81 8 0.099 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0060284 Not Cancer Driver No 42 0.115 45 1 0.022 1
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0060284 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0060284 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0060284 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0060284 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0060284 Not Cancer Driver No 44 0.145 210 26 0.124 1
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0060284 Not Cancer Driver No 100 0.181 17 7 0.412 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0060284 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0060284 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0060284 Not Cancer Driver No 286 0.283 631 178 0.282 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0060284 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0060284 Not Cancer Driver No 1 0.006 73 0 0.0 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0060284 Census Yes 118 0.143 435 51 0.117 0
HOOK3 HOOK3 Q86VS8 Protein Hook homolog 3 chr8 GO:0060284 Census Yes 79 0.11 493 55 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0060284 Not Cancer Driver No 20 0.129 17 6 0.353 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0060284 Not Cancer Driver No 14 0.104 52 7 0.135 0
ID4 ID4 P47928 DNA-binding protein inhibitor ID-4 chr6 GO:0060284 Not Cancer Driver No 4 0.025 71 1 0.014 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0060284 Not Cancer Driver No 45 0.231 87 23 0.264 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0060284 Census, Compendium Yes 106 0.14 211 31 0.147 1
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0060284 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0060284 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0060284 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0060284 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0060284 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0060284 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0060284 Census, Compendium Yes 102 0.111 315 40 0.127 2
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0060284 Not Cancer Driver No 45 0.1 71 9 0.127 0
INS INS P01308 Insulin chr11 GO:0060284 Not Cancer Driver No 15 0.136 5 1 0.2 22
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0060284 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0060284 Not Cancer Driver No 31 0.085 185 17 0.092 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0060284 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0060284 Not Cancer Driver No 28 0.061 216 7 0.032 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0060284 Not Cancer Driver No 183 0.135 804 100 0.124 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0060284 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0060284 Not Cancer Driver No 122 0.115 337 44 0.131 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0060284 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF14 KIF14 Q15058 Kinesin-like protein KIF14 chr1 GO:0060284 Not Cancer Driver No 222 0.135 774 102 0.132 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0060284 Census, Compendium Yes 226 0.232 83 33 0.398 21
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0060284 Not Cancer Driver No 228 0.181 442 75 0.17 54
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0060284 Not Cancer Driver No 119 0.138 63 3 0.048 104
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 GO:0060284 Not Cancer Driver No 60 0.148 203 28 0.138 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0060284 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0060284 Not Cancer Driver No 203 0.312 291 97 0.333 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0060284 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0060284 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0060284 Not Cancer Driver No 55 0.161 8 0 0.0 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0060284 Not Cancer Driver No 37 0.177 86 12 0.14 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0060284 Not Cancer Driver No 99 0.177 456 84 0.184 1
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0060284 Not Cancer Driver No 65 0.184 9 0 0.0 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0060284 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0060284 Not Cancer Driver No 233 0.122 265 28 0.106 11
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0060284 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0060284 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0060284 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTF LTF P02788 Lactotransferrin chr3 GO:0060284 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0060284 Census Yes 95 0.186 84 12 0.143 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0060284 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0060284 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0060284 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0060284 Compendium Yes 367 0.201 1726 340 0.197 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0060284 Census Yes 157 0.163 593 91 0.153 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0060284 Not Cancer Driver No 128 0.169 750 126 0.168 18
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0060284 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0060284 Not Cancer Driver No 218 0.236 124 33 0.266 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0060284 Not Cancer Driver No 15 0.105 20 2 0.1 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0060284 Not Cancer Driver No 363 0.128 476 59 0.124 3
MELTF MELTF P08582 Melanotransferrin chr3 GO:0060284 Not Cancer Driver No 106 0.144 23 6 0.261 0
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0060284 Census Yes 77 0.121 129 19 0.147 14
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0060284 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0060284 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0060284 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0060284 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0060284 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0060284 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYOC MYOC Q99972 Myocilin chr1 GO:0060284 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0060284 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0060284 Not Cancer Driver No 36 0.161 132 20 0.152 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0060284 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0060284 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0060284 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0060284 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0060284 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0060284 Not Cancer Driver No 155 0.172 685 120 0.175 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0060284 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0060284 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0060284 Not Cancer Driver No 38 0.104 325 34 0.105 0
NKX6-2 NKX6-2 Q9C056 Homeobox protein Nkx-6.2 chr10 GO:0060284 Not Cancer Driver No 27 0.097 137 23 0.168 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0060284 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0060284 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0060284 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0060284 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0060284 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0060284 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0060284 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0060284 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0060284 Not Cancer Driver No 75 0.195 57 6 0.105 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0060284 Compendium Yes 146 0.158 211 31 0.147 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0060284 Not Cancer Driver No 57 0.094 66 4 0.061 2
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0060284 Census, Compendium Yes 249 0.297 57 21 0.368 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0060284 Not Cancer Driver No 233 0.123 553 60 0.108 0
OLFM4 OLFM4 Q6UX06 Olfactomedin-4 chr13 GO:0060284 Not Cancer Driver No 117 0.229 54 11 0.204 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0060284 Census Yes 37 0.115 256 37 0.145 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0060284 Not Cancer Driver No 36 0.111 278 29 0.104 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0060284 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0060284 Not Cancer Driver No 23 0.128 3 0 0.0 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0060284 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0060284 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 GO:0060284 Not Cancer Driver No 87 0.138 67 13 0.194 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0060284 Not Cancer Driver No 72 0.171 337 56 0.166 38
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 GO:0060284 Census Yes 152 0.075 1665 134 0.08 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0060284 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0060284 Not Cancer Driver No 113 0.129 163 23 0.141 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0060284 Not Cancer Driver No 24 0.079 155 12 0.077 1
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0060284 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0060284 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0060284 Not Cancer Driver No 243 0.13 199 34 0.171 0
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0060284 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0060284 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0060284 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0060284 Compendium Yes 85 0.163 140 27 0.193 7
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0060284 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0060284 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0060284 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0060284 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0060284 Not Cancer Driver No 83 0.13 72 6 0.083 0
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0060284 Not Cancer Driver No 73 0.158 41 9 0.22 36
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0060284 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRTG PRTG Q2VWP7 Protogenin chr15 GO:0060284 Not Cancer Driver No 192 0.167 271 49 0.181 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0060284 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0060284 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTHLH_ENST00000539239 PTHLH P12272 Parathyroid hormone-related protein chr12 GO:0060284 Not Cancer Driver No 44 0.249 132 40 0.303 2
PTN PTN P21246 Pleiotrophin chr7 GO:0060284 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0060284 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0060284 Not Cancer Driver No 250 0.128 829 111 0.134 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0060284 Not Cancer Driver No 480 0.207 978 216 0.221 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0060284 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0060284 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0060284 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0060284 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0060284 Not Cancer Driver No 216 0.144 803 116 0.144 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0060284 Not Cancer Driver No 63 0.121 194 27 0.139 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0060284 Not Cancer Driver No 115 0.118 9 2 0.222 0
RELN RELN P78509 Reelin chr7 GO:0060284 Not Cancer Driver No 761 0.22 107 19 0.178 7
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0060284 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0060284 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFLNA_ENST00000546355 RFLNA Q6ZTI6 Refilin-A chr12 GO:0060284 Not Cancer Driver No 23 0.106 122 8 0.066 0
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 GO:0060284 Not Cancer Driver No 113 0.151 308 41 0.133 0
RHEB RHEB Q15382 GTP-binding protein Rheb chr7 GO:0060284 Not Cancer Driver No 30 0.163 0 0 0.0 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0060284 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF10_ENST00000325954 RNF10 Q8N5U6 RING finger protein 10 chr12 GO:0060284 Not Cancer Driver No 108 0.133 455 63 0.138 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0060284 Not Cancer Driver No 86 0.136 168 26 0.155 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0060284 Compendium Yes 91 0.133 601 87 0.145 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0060284 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0060284 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPS19_ENST00000600467 RPS19 P39019 40S ribosomal protein S19 chr19 GO:0060284 Not Cancer Driver No 15 0.103 61 3 0.049 23
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0060284 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0060284 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0060284 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0060284 Not Cancer Driver No 75 0.16 204 29 0.142 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0060284 Not Cancer Driver No 55 0.091 85 4 0.047 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0060284 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0060284 Not Cancer Driver No 38 0.108 16 3 0.188 2
S1PR3 S1PR3 Q99500 Sphingosine 1-phosphate receptor 3 chr9 GO:0060284 Not Cancer Driver No 69 0.183 28 4 0.143 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0060284 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0060284 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0060284 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0060284 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0060284 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0060284 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0060284 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0060284 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0060284 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0060284 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0060284 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0060284 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0060284 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0060284 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0060284 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0060284 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0060284 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0060284 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0060284 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0060284 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0060284 Not Cancer Driver No 62 0.156 0 0 0.0 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0060284 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0060284 Not Cancer Driver No 67 0.202 200 40 0.2 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0060284 Census Yes 68 0.108 470 52 0.111 0
SIGLEC15 SIGLEC15 Q6ZMC9 Sialic acid-binding Ig-like lectin 15 chr18 GO:0060284 Not Cancer Driver No 27 0.082 99 15 0.152 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0060284 Not Cancer Driver No 56 0.144 85 17 0.2 0
SKI SKI P12755 Ski oncogene chr1 GO:0060284 Census Yes 44 0.06 432 26 0.06 14
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0060284 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0060284 Not Cancer Driver No 68 0.127 80 16 0.2 0
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0060284 Not Cancer Driver No 221 0.144 36 1 0.028 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0060284 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0060284 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0060284 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0060284 Census, Compendium Yes 112 0.142 241 27 0.112 1
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0060284 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0060284 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0060284 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0060284 Not Cancer Driver No 43 0.096 403 39 0.097 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 GO:0060284 Not Cancer Driver No 112 0.168 396 68 0.172 1
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 GO:0060284 Not Cancer Driver No 63 0.119 75 12 0.16 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0060284 Not Cancer Driver No 56 0.178 296 54 0.182 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0060284 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRF SRF P11831 Serum response factor chr6 GO:0060284 Not Cancer Driver No 44 0.087 443 42 0.095 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0060284 Census Yes 53 0.134 356 48 0.135 0
SS18L2 SS18L2 Q9UHA2 SS18-like protein 2 chr3 GO:0060284 Not Cancer Driver No 4 0.052 7 1 0.143 0
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0060284 Not Cancer Driver No 68 0.119 486 54 0.111 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0060284 Not Cancer Driver No 153 0.114 830 90 0.108 2
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0060284 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0060284 Not Cancer Driver No 111 0.261 107 41 0.383 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0060284 Not Cancer Driver No 22 0.068 27 1 0.037 0
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0060284 Not Cancer Driver No 44 0.101 253 25 0.099 0
TCP11_ENST00000512012 TCP11 Q8WWU5 T-complex protein 11 homolog chr6 GO:0060284 Not Cancer Driver No 78 0.155 112 13 0.116 0
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0060284 Not Cancer Driver No 492 0.178 498 63 0.127 3
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0060284 Not Cancer Driver No 63 0.101 339 35 0.103 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0060284 Not Cancer Driver No 41 0.105 41 4 0.098 10
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0060284 Not Cancer Driver No 24 0.149 5 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0060284 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 GO:0060284 Not Cancer Driver No 24 0.085 220 15 0.068 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0060284 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNF TNF P01375 Tumor necrosis factor chr6 GO:0060284 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0060284 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0060284 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0060284 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNR TNR Q92752 Tenascin-R chr1 GO:0060284 Not Cancer Driver No 496 0.365 358 128 0.358 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0060284 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0060284 Not Cancer Driver No 82 0.129 443 55 0.124 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0060284 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0060284 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0060284 Not Cancer Driver No 58 0.124 132 14 0.106 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0060284 Not Cancer Driver No 115 0.152 173 30 0.173 0
TRIM58 TRIM58 Q8NG06 E3 ubiquitin-protein ligase TRIM58 chr1 GO:0060284 Not Cancer Driver No 194 0.399 84 41 0.488 0
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0060284 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0060284 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0060284 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0060284 Not Cancer Driver No 105 0.137 175 23 0.131 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0060284 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0060284 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTPA TTPA P49638 Alpha-tocopherol transfer protein chr8 GO:0060284 Not Cancer Driver No 53 0.191 20 1 0.05 7
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0060284 Not Cancer Driver No 34 0.097 59 8 0.136 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0060284 Not Cancer Driver No 24 0.212 28 8 0.286 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0060284 Not Cancer Driver No 109 0.137 141 24 0.17 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0060284 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0060284 Not Cancer Driver No 132 0.127 519 84 0.162 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0060284 Not Cancer Driver No 120 0.11 248 30 0.121 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0060284 Not Cancer Driver No 36 0.108 234 25 0.107 1
VCL VCL P18206 Vinculin chr10 GO:0060284 Not Cancer Driver No 114 0.101 673 80 0.119 2
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0060284 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0060284 Not Cancer Driver No 128 0.305 37 12 0.324 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0060284 Not Cancer Driver No 181 0.119 792 100 0.126 5
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0060284 Not Cancer Driver No 104 0.183 345 65 0.188 1
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0060284 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0060284 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0060284 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0060284 Not Cancer Driver No 93 0.266 18 9 0.5 4
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0060284 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZDHHC21 ZDHHC21 Q8IVQ6 Palmitoyltransferase ZDHHC21 chr9 GO:0060284 Not Cancer Driver No 34 0.128 0 0 0.0 0
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0060284 Not Cancer Driver No 45 0.109 140 22 0.157 1
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0060284 Not Cancer Driver No 185 0.138 942 133 0.141 1