Total number of protein in "GO:0043542" GO term: 67
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0043542 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ADGRA2 | ADGRA2 | Q96PE1 | Adhesion G protein-coupled receptor A2 | chr8 | GO:0043542 | Not Cancer Driver | No | 140 | 0.105 | 417 | 32 | 0.077 | 0 |
| ADTRP_ENST00000414691 | ADTRP | Q96IZ2 | Androgen-dependent TFPI-regulating protein | chr6 | GO:0043542 | Not Cancer Driver | No | 41 | 0.178 | 2 | 0 | 0.0 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0043542 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AMOT | AMOT | Q4VCS5 | Angiomotin | chrX | GO:0043542 | Not Cancer Driver | No | 161 | 0.149 | 909 | 128 | 0.141 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0043542 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| CCN3 | CCN3 | P48745 | CCN family member 3 | chr8 | GO:0043542 | Not Cancer Driver | No | 66 | 0.185 | 19 | 1 | 0.053 | 0 |
| CDH13_ENST00000567109 | CDH13 | P55290 | Cadherin-13 | chr16 | GO:0043542 | Not Cancer Driver | No | 168 | 0.236 | 235 | 59 | 0.251 | 0 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0043542 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CLEC14A | CLEC14A | Q86T13 | C-type lectin domain family 14 member A | chr14 | GO:0043542 | Not Cancer Driver | No | 147 | 0.3 | 182 | 60 | 0.33 | 0 |
| CORO1B | CORO1B | Q9BR76 | Coronin-1B | chr11 | GO:0043542 | Not Cancer Driver | No | 41 | 0.084 | 138 | 10 | 0.072 | 0 |
| CXCL13 | CXCL13 | O43927 | C-X-C motif chemokine 13 | chr4 | GO:0043542 | Not Cancer Driver | No | 11 | 0.101 | 0 | 0 | 0.0 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0043542 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| DPP4 | DPP4 | P27487 | Dipeptidyl peptidase 4 | chr2 | GO:0043542 | Not Cancer Driver | No | 151 | 0.197 | 8 | 1 | 0.125 | 0 |
| EDN2 | EDN2 | P20800 | Endothelin-2 | chr1 | GO:0043542 | Not Cancer Driver | No | 21 | 0.118 | 87 | 13 | 0.149 | 0 |
| EFNB2_ENST00000245323 | EFNB2 | P52799 | Ephrin-B2 | chr13 | GO:0043542 | Not Cancer Driver | No | 42 | 0.126 | 97 | 15 | 0.155 | 0 |
| EGR3 | EGR3 | Q06889 | Early growth response protein 3 | chr8 | GO:0043542 | Not Cancer Driver | No | 60 | 0.155 | 252 | 46 | 0.183 | 0 |
| EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0043542 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
| EPHB4 | EPHB4 | P54760 | Ephrin type-B receptor 4 | chr7 | GO:0043542 | Not Cancer Driver | No | 125 | 0.127 | 184 | 19 | 0.103 | 11 |
| FAP | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0043542 | Not Cancer Driver | No | 158 | 0.208 | 6 | 2 | 0.333 | 0 |
| FGF2_ENST00000614010 | FGF2 | P09038 | Fibroblast growth factor 2 | chr4 | GO:0043542 | Not Cancer Driver | No | 18 | 0.062 | 183 | 5 | 0.027 | 0 |
| FSTL1 | FSTL1 | Q12841 | Follistatin-related protein 1 | chr3 | GO:0043542 | Not Cancer Driver | No | 41 | 0.133 | 51 | 7 | 0.137 | 0 |
| GIPC1 | GIPC1 | O14908 | PDZ domain-containing protein GIPC1 | chr19 | GO:0043542 | Not Cancer Driver | No | 47 | 0.141 | 138 | 17 | 0.123 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0043542 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| GPX1_ENST00000620890 | GPX1 | P07203 | Glutathione peroxidase 1 | chr3 | GO:0043542 | Not Cancer Driver | No | 38 | 0.187 | 12 | 1 | 0.083 | 0 |
| GREM1 | GREM1 | O60565 | Gremlin-1 | chr15 | GO:0043542 | Not Cancer Driver | No | 25 | 0.136 | 77 | 12 | 0.156 | 0 |
| ID1 | ID1 | P41134 | DNA-binding protein inhibitor ID-1 | chr20 | GO:0043542 | Not Cancer Driver | No | 20 | 0.129 | 17 | 6 | 0.353 | 0 |
| ITGB1_ENST00000302278 | ITGB1 | P05556 | Integrin beta-1 | chr10 | GO:0043542 | Not Cancer Driver | No | 103 | 0.129 | 84 | 10 | 0.119 | 0 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0043542 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| LGALS12_ENST00000394618 | LGALS12 | Q96DT0 | Galectin-12 | chr11 | GO:0043542 | Not Cancer Driver | No | 49 | 0.146 | 8 | 2 | 0.25 | 0 |
| LGALS8_ENST00000366584 | LGALS8 | O00214 | Galectin-8 | chr1 | GO:0043542 | Not Cancer Driver | No | 43 | 0.136 | 31 | 6 | 0.194 | 0 |
| LOXL2 | LOXL2 | Q9Y4K0 | Lysyl oxidase homolog 2 | chr8 | GO:0043542 | Not Cancer Driver | No | 134 | 0.173 | 39 | 4 | 0.103 | 0 |
| LPXN_ENST00000395074 | LPXN | O60711 | Leupaxin | chr11 | GO:0043542 | Not Cancer Driver | No | 43 | 0.111 | 134 | 16 | 0.119 | 0 |
| MIA3 | MIA3 | Q5JRA6 | Transport and Golgi organization protein 1 homolog | chr1 | GO:0043542 | Not Cancer Driver | No | 222 | 0.116 | 1490 | 178 | 0.119 | 0 |
| MMRN2 | MMRN2 | Q9H8L6 | Multimerin-2 | chr10 | GO:0043542 | Not Cancer Driver | No | 98 | 0.103 | 420 | 49 | 0.117 | 0 |
| MYH9 | MYH9 | P35579 | Myosin-9 | chr22 | GO:0043542 | Census, Compendium | Yes | 310 | 0.158 | 1120 | 160 | 0.143 | 17 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0043542 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NR4A1_ENST00000394825 | NR4A1 | P22736 | Nuclear receptor subfamily 4 group A member 1 | chr12 | GO:0043542 | Not Cancer Driver | No | 62 | 0.104 | 252 | 24 | 0.095 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0043542 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| PAXIP1 | PAXIP1 | Q6ZW49 | PAX-interacting protein 1 | chr7 | GO:0043542 | Not Cancer Driver | No | 120 | 0.112 | 461 | 39 | 0.085 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0043542 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3R3_ENST00000372006 | PIK3R3 | Q92569 | Phosphatidylinositol 3-kinase regulatory subunit gamma | chr1 | GO:0043542 | Not Cancer Driver | No | 51 | 0.111 | 149 | 20 | 0.134 | 0 |
| PLEKHG5_ENST00000400913 | PLEKHG5 | O94827 | Pleckstrin homology domain-containing family G member 5 | chr1 | GO:0043542 | Not Cancer Driver | No | 93 | 0.092 | 537 | 54 | 0.101 | 3 |
| PLXND1 | PLXND1 | Q9Y4D7 | Plexin-D1 | chr3 | GO:0043542 | Not Cancer Driver | No | 246 | 0.128 | 321 | 35 | 0.109 | 0 |
| PRKX | PRKX | P51817 | cAMP-dependent protein kinase catalytic subunit PRKX | chrX | GO:0043542 | Not Cancer Driver | No | 54 | 0.151 | 69 | 3 | 0.043 | 0 |
| PRSS3 | PRSS3 | P35030 | Trypsin-3 | chr9 | GO:0043542 | Not Cancer Driver | No | 50 | 0.164 | 30 | 0 | 0.0 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0043542 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0043542 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTP4A3_ENST00000521578 | PTP4A3 | O75365 | Protein tyrosine phosphatase type IVA 3 | chr8 | GO:0043542 | Not Cancer Driver | No | 30 | 0.173 | 3 | 0 | 0.0 | 0 |
| PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | GO:0043542 | Not Cancer Driver | No | 62 | 0.105 | 341 | 24 | 0.07 | 0 |
| RAB13 | RAB13 | P51153 | Ras-related protein Rab-13 | chr1 | GO:0043542 | Not Cancer Driver | No | 19 | 0.094 | 40 | 0 | 0.0 | 0 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0043542 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| ROBO1 | ROBO1 | Q9Y6N7 | Roundabout homolog 1 | chr3 | GO:0043542 | Not Cancer Driver | No | 353 | 0.214 | 1122 | 234 | 0.209 | 0 |
| S100A2_ENST00000368709 | S100A2 | P29034 | Protein S100-A2 | chr1 | GO:0043542 | Not Cancer Driver | No | 16 | 0.163 | 6 | 2 | 0.333 | 0 |
| S100P | S100P | P25815 | Protein S100-P | chr4 | GO:0043542 | Not Cancer Driver | No | 7 | 0.074 | 3 | 1 | 0.333 | 0 |
| SCARB1_ENST00000415380 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0043542 | Not Cancer Driver | No | 53 | 0.096 | 6 | 1 | 0.167 | 0 |
| SCG2 | SCG2 | P13521 | Secretogranin-2 | chr2 | GO:0043542 | Not Cancer Driver | No | 116 | 0.188 | 531 | 103 | 0.194 | 0 |
| SLIT2 | SLIT2 | O94813 | Slit homolog 2 protein | chr4 | GO:0043542 | Not Cancer Driver | No | 428 | 0.28 | 31 | 13 | 0.419 | 0 |
| SOX18 | SOX18 | P35713 | Transcription factor SOX-18 | chr20 | GO:0043542 | Not Cancer Driver | No | 10 | 0.026 | 321 | 10 | 0.031 | 2 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0043542 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| STARD13 | STARD13 | Q9Y3M8 | StAR-related lipid transfer protein 13 | chr13 | GO:0043542 | Not Cancer Driver | No | 177 | 0.159 | 494 | 78 | 0.158 | 0 |
| STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0043542 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
| TDGF1 | TDGF1 | P13385 | Teratocarcinoma-derived growth factor 1 | chr3 | GO:0043542 | Not Cancer Driver | No | 39 | 0.207 | 25 | 2 | 0.08 | 0 |
| TGFBR1_ENST00000374994 | TGFBR1 | P36897 | TGF-beta receptor type-1 | chr9 | GO:0043542 | Not Cancer Driver | No | 86 | 0.171 | 23 | 3 | 0.13 | 15 |
| TNFSF12 | TNFSF12 | O43508 | Tumor necrosis factor ligand superfamily member 12 | chr17 | GO:0043542 | Not Cancer Driver | No | 28 | 0.112 | 109 | 8 | 0.073 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0043542 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VSTM4 | VSTM4 | Q8IW00 | V-set and transmembrane domain-containing protein 4 | chr10 | GO:0043542 | Not Cancer Driver | No | 91 | 0.284 | 47 | 9 | 0.191 | 0 |