Total number of protein in "GO:0033209" GO term: 54
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:0033209 | Not Cancer Driver | No | 131 | 0.144 | 244 | 42 | 0.172 | 8 |
| AIM2 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0033209 | Not Cancer Driver | No | 73 | 0.213 | 78 | 22 | 0.282 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0033209 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BIRC3_ENST00000532808 | BIRC3 | Q13489 | Baculoviral IAP repeat-containing protein 3 | chr11 | GO:0033209 | Census, Compendium | Yes | 77 | 0.127 | 98 | 16 | 0.163 | 0 |
| CARD14 | CARD14 | Q9BXL6 | Caspase recruitment domain-containing protein 14 | chr17 | GO:0033209 | Not Cancer Driver | No | 99 | 0.099 | 296 | 36 | 0.122 | 11 |
| CD70_ENST00000245903 | CD70 | P32970 | CD70 antigen | chr19 | GO:0033209 | Not Cancer Driver | No | 33 | 0.171 | 11 | 2 | 0.182 | 0 |
| CDIP1 | CDIP1 | Q9H305 | Cell death-inducing p53-target protein 1 | chr16 | GO:0033209 | Not Cancer Driver | No | 10 | 0.048 | 119 | 7 | 0.059 | 0 |
| CHUK | CHUK | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha | chr10 | GO:0033209 | Not Cancer Driver | No | 74 | 0.099 | 116 | 9 | 0.078 | 0 |
| CLDN18 | CLDN18 | P56856 | Claudin-18 | chr3 | GO:0033209 | Not Cancer Driver | No | 44 | 0.169 | 21 | 5 | 0.238 | 0 |
| COMMD7 | COMMD7 | Q86VX2 | COMM domain-containing protein 7 | chr20 | GO:0033209 | Not Cancer Driver | No | 29 | 0.145 | 21 | 0 | 0.0 | 0 |
| EDA2R_ENST00000451436 | EDA2R | Q9HAV5 | Tumor necrosis factor receptor superfamily member 27 | chrX | GO:0033209 | Not Cancer Driver | No | 52 | 0.175 | 72 | 11 | 0.153 | 0 |
| EIF5A_ENST00000419711 | EIF5A | P63241 | Eukaryotic translation initiation factor 5A-1 | chr17 | GO:0033209 | Not Cancer Driver | No | 37 | 0.24 | 21 | 5 | 0.238 | 5 |
| EXT1 | EXT1 | Q16394 | Exostosin-1 | chr8 | GO:0033209 | Census | Yes | 107 | 0.143 | 58 | 7 | 0.121 | 12 |
| FAS | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0033209 | Census, Compendium | Yes | 55 | 0.164 | 62 | 18 | 0.29 | 22 |
| FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0033209 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0033209 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0033209 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0033209 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KRT18_ENST00000388837 | KRT18 | P05783 | Keratin, type I cytoskeletal 18 | chr12 | GO:0033209 | Not Cancer Driver | No | 57 | 0.133 | 179 | 21 | 0.117 | 4 |
| LIMS1_ENST00000393310 | LIMS1 | P48059 | LIM and senescent cell antigen-like-containing domain protein 1 | chr2 | GO:0033209 | Not Cancer Driver | No | 34 | 0.105 | 0 | 0 | 0.0 | 0 |
| NFKBIA | NFKBIA | P25963 | NF-kappa-B inhibitor alpha | chr14 | GO:0033209 | Compendium | Yes | 37 | 0.117 | 102 | 9 | 0.088 | 1 |
| PIAS3 | PIAS3 | Q9Y6X2 | E3 SUMO-protein ligase PIAS3 | chr1 | GO:0033209 | Not Cancer Driver | No | 70 | 0.111 | 266 | 31 | 0.117 | 0 |
| PLVAP | PLVAP | Q9BX97 | Plasmalemma vesicle-associated protein | chr19 | GO:0033209 | Not Cancer Driver | No | 96 | 0.217 | 174 | 39 | 0.224 | 1 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0033209 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0033209 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| PYDC1 | PYDC1 | Q8WXC3 | Pyrin domain-containing protein 1 | chr16 | GO:0033209 | Not Cancer Driver | No | 28 | 0.315 | 0 | 0 | 0.0 | 0 |
| RELA | RELA | Q04206 | Transcription factor p65 | chr11 | GO:0033209 | Compendium | Yes | 75 | 0.136 | 400 | 48 | 0.12 | 0 |
| RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0033209 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
| RRAGA | RRAGA | Q7L523 | Ras-related GTP-binding protein A | chr9 | GO:0033209 | Not Cancer Driver | No | 30 | 0.096 | 0 | 0 | 0.0 | 0 |
| ST18 | ST18 | O60284 | Suppression of tumorigenicity 18 protein | chr8 | GO:0033209 | Not Cancer Driver | No | 330 | 0.315 | 820 | 282 | 0.344 | 0 |
| STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0033209 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
| TMSB4X_ENST00000380633 | TMSB4X | P62328 | Thymosin beta-4 | chrX | GO:0033209 | Census | Yes | 7 | 0.159 | 44 | 7 | 0.159 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0033209 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0033209 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TNFRSF13C | TNFRSF13C | Q96RJ3 | Tumor necrosis factor receptor superfamily member 13C | chr22 | GO:0033209 | Not Cancer Driver | No | 17 | 0.092 | 128 | 15 | 0.117 | 0 |
| TNFRSF14 | TNFRSF14 | Q92956 | Tumor necrosis factor receptor superfamily member 14 | chr1 | GO:0033209 | Census, Compendium | Yes | 33 | 0.117 | 54 | 8 | 0.148 | 0 |
| TNFRSF17 | TNFRSF17 | Q02223 | Tumor necrosis factor receptor superfamily member 17 | chr16 | GO:0033209 | Census | Yes | 28 | 0.152 | 1 | 0 | 0.0 | 0 |
| TNFRSF18_ENST00000379268 | TNFRSF18 | Q9Y5U5 | Tumor necrosis factor receptor superfamily member 18 | chr1 | GO:0033209 | Not Cancer Driver | No | 22 | 0.091 | 23 | 1 | 0.043 | 0 |
| TNFRSF19 | TNFRSF19 | Q9NS68 | Tumor necrosis factor receptor superfamily member 19 | chr13 | GO:0033209 | Not Cancer Driver | No | 72 | 0.17 | 103 | 19 | 0.184 | 0 |
| TNFRSF1A | TNFRSF1A | P19438 | Tumor necrosis factor receptor superfamily member 1A | chr12 | GO:0033209 | Not Cancer Driver | No | 58 | 0.127 | 111 | 15 | 0.135 | 12 |
| TNFRSF1B | TNFRSF1B | P20333 | Tumor necrosis factor receptor superfamily member 1B | chr1 | GO:0033209 | Not Cancer Driver | No | 48 | 0.104 | 229 | 28 | 0.122 | 0 |
| TNFRSF25_ENST00000356876 | TNFRSF25 | Q93038 | Tumor necrosis factor receptor superfamily member 25 | chr1 | GO:0033209 | Not Cancer Driver | No | 38 | 0.091 | 72 | 6 | 0.083 | 0 |
| TNFRSF4 | TNFRSF4 | P43489 | Tumor necrosis factor receptor superfamily member 4 | chr1 | GO:0033209 | Not Cancer Driver | No | 30 | 0.108 | 94 | 14 | 0.149 | 1 |
| TNFSF11 | TNFSF11 | O14788 | Tumor necrosis factor ligand superfamily member 11 | chr13 | GO:0033209 | Not Cancer Driver | No | 52 | 0.164 | 56 | 1 | 0.018 | 1 |
| TNFSF13B | TNFSF13B | Q9Y275 | Tumor necrosis factor ligand superfamily member 13B | chr13 | GO:0033209 | Not Cancer Driver | No | 41 | 0.144 | 91 | 15 | 0.165 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0033209 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0033209 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAF1 | TRAF1 | Q13077 | TNF receptor-associated factor 1 | chr9 | GO:0033209 | Not Cancer Driver | No | 51 | 0.123 | 63 | 9 | 0.143 | 0 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0033209 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0033209 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TRAF3_ENST00000392745 | TRAF3 | Q13114 | TNF receptor-associated factor 3 | chr14 | GO:0033209 | Compendium | Yes | 61 | 0.107 | 101 | 9 | 0.089 | 1 |
| TRAF5_ENST00000336184 | TRAF5 | O00463 | TNF receptor-associated factor 5 | chr1 | GO:0033209 | Not Cancer Driver | No | 61 | 0.11 | 59 | 5 | 0.085 | 0 |
| TRAF6_ENST00000348124 | TRAF6 | Q9Y4K3 | TNF receptor-associated factor 6 | chr11 | GO:0033209 | Not Cancer Driver | No | 67 | 0.128 | 62 | 7 | 0.113 | 0 |
| TXNDC17 | TXNDC17 | Q9BRA2 | Thioredoxin domain-containing protein 17 | chr17 | GO:0033209 | Not Cancer Driver | No | 8 | 0.065 | 0 | 0 | 0.0 | 0 |