Filter in search result
Please select a valid state.

Total number of protein in "GO:0006979" GO term:  262

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0006979 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0006979 Census, Compendium Yes 139 0.123 604 73 0.121 2
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0006979 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0006979 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADPRHL2 ADPRS Q9NX46 ADP-ribosylhydrolase ARH3 chr1 GO:0006979 Not Cancer Driver No 32 0.088 49 4 0.082 1
AGAP3_ENST00000622464 AGAP3 Q96P47 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 chr7 GO:0006979 Not Cancer Driver No 116 0.133 404 55 0.136 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0006979 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0006979 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0006979 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0006979 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0006979 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALDH3B1 ALDH3B1 P43353 Aldehyde dehydrogenase family 3 member B1 chr11 GO:0006979 Not Cancer Driver No 36 0.077 23 6 0.261 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0006979 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANGPTL7 ANGPTL7 O43827 Angiopoietin-related protein 7 chr1 GO:0006979 Not Cancer Driver No 38 0.11 33 7 0.212 0
ANKZF1 ANKZF1 Q9H8Y5 Ankyrin repeat and zinc finger domain-containing protein 1 chr2 GO:0006979 Not Cancer Driver No 77 0.106 507 57 0.112 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0006979 Not Cancer Driver No 59 0.171 61 12 0.197 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006979 Not Cancer Driver No 34 0.107 103 14 0.136 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0006979 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0006979 Not Cancer Driver No 34 0.18 13 2 0.154 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0006979 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0006979 Not Cancer Driver No 23 0.112 48 4 0.083 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0006979 Not Cancer Driver No 128 0.166 418 71 0.17 17
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0006979 Not Cancer Driver No 36 0.101 101 6 0.059 9
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0006979 Not Cancer Driver No 39 0.145 4 1 0.25 0
AREG AREG P15514 Amphiregulin chr4 GO:0006979 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0006979 Not Cancer Driver No 41 0.127 83 12 0.145 9
ATOX1_ENST00000522710 ATOX1 O00244 Copper transport protein ATOX1 chr5 GO:0006979 Not Cancer Driver No 2 0.029 0 0 0.0 0
ATRN ATRN O75882 Attractin chr20 GO:0006979 Not Cancer Driver No 136 0.095 53 5 0.094 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0006979 Not Cancer Driver No 168 0.188 341 64 0.188 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0006979 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0006979 Not Cancer Driver No 38 0.18 58 9 0.155 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006979 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0006979 Not Cancer Driver No 45 0.1 190 19 0.1 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0006979 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0006979 Census, Compendium Yes 147 0.223 114 27 0.237 110
C19orf12 C19orf12 Q9NSK7 Protein C19orf12 chr19 GO:0006979 Not Cancer Driver No 23 0.151 7 0 0.0 15
CA3 CA3 P07451 Carbonic anhydrase 3 chr8 GO:0006979 Not Cancer Driver No 61 0.235 64 13 0.203 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0006979 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0006979 Not Cancer Driver No 81 0.116 46 11 0.239 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0006979 Census Yes 32 0.116 62 5 0.081 0
CAT CAT P04040 Catalase chr11 GO:0006979 Not Cancer Driver No 70 0.133 176 18 0.102 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0006979 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0006979 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0006979 Not Cancer Driver No 40 0.135 1 0 0.0 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0006979 Not Cancer Driver No 144 0.23 186 33 0.177 2
CHUK CHUK O15111 Inhibitor of nuclear factor kappa-B kinase subunit alpha chr10 GO:0006979 Not Cancer Driver No 74 0.099 116 9 0.078 0
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0006979 Not Cancer Driver No 45 0.157 16 2 0.125 16
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0006979 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CRK CRK P46108 Adapter molecule crk chr17 GO:0006979 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0006979 Not Cancer Driver No 22 0.126 59 11 0.186 4
CRYGD CRYGD P07320 Gamma-crystallin D chr2 GO:0006979 Not Cancer Driver No 28 0.161 0 0 0.0 6
CYB5B CYB5B O43169 Cytochrome b5 type B chr16 GO:0006979 Not Cancer Driver No 17 0.113 58 2 0.034 0
CYGB CYGB Q8WWM9 Cytoglobin chr17 GO:0006979 Not Cancer Driver No 32 0.168 47 5 0.106 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0006979 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0006979 Not Cancer Driver No 87 0.176 21 6 0.286 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0006979 Not Cancer Driver No 193 0.135 114 11 0.096 0
DGKK DGKK Q5KSL6 Diacylglycerol kinase kappa chrX GO:0006979 Not Cancer Driver No 262 0.206 382 90 0.236 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0006979 Not Cancer Driver No 55 0.107 0 0 0.0 6
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0006979 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0006979 Not Cancer Driver No 245 0.158 182 25 0.137 3
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0006979 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0006979 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0006979 Census, Compendium Yes 444 0.367 223 35 0.157 1
EPX EPX P11678 Eosinophil peroxidase chr17 GO:0006979 Not Cancer Driver No 144 0.201 55 6 0.109 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006979 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006979 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006979 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006979 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0006979 Not Cancer Driver No 25 0.063 53 8 0.151 7
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0006979 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0006979 Not Cancer Driver No 48 0.103 32 5 0.156 0
ETFDH ETFDH Q16134 Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial chr4 GO:0006979 Not Cancer Driver No 61 0.099 64 4 0.062 12
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0006979 Census, Compendium Yes 120 0.161 284 44 0.155 11
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0006979 Not Cancer Driver No 34 0.268 0 0 0.0 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0006979 Not Cancer Driver No 114 0.139 145 21 0.145 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0006979 Not Cancer Driver No 10 0.093 58 4 0.069 0
FOS FOS P01100 Protein c-Fos chr14 GO:0006979 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0006979 Not Cancer Driver No 24 0.089 271 24 0.089 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0006979 Not Cancer Driver No 16 0.076 73 0 0.0 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0006979 Not Cancer Driver No 92 0.171 70 13 0.186 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0006979 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0006979 Not Cancer Driver No 32 0.117 31 3 0.097 0
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0006979 Not Cancer Driver No 12 0.073 10 1 0.1 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0006979 Not Cancer Driver No 38 0.187 12 1 0.083 0
GPX2_ENST00000612794 GPX2 P18283 Glutathione peroxidase 2 chr14 GO:0006979 Not Cancer Driver No 26 0.137 0 0 0.0 0
GPX3_ENST00000622181 GPX3 P22352 Glutathione peroxidase 3 chr5 GO:0006979 Not Cancer Driver No 29 0.128 7 0 0.0 0
GPX4_ENST00000616066 GPX4 P36969 Phospholipid hydroperoxide glutathione peroxidase chr19 GO:0006979 Not Cancer Driver No 14 0.071 0 0 0.0 0
GPX6_ENST00000612264 GPX6 P59796 Glutathione peroxidase 6 chr6 GO:0006979 Not Cancer Driver No 66 0.299 0 0 0.0 0
GSS_ENST00000216951 GSS P48637 Glutathione synthetase chr20 GO:0006979 Not Cancer Driver No 61 0.129 49 6 0.122 14
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0006979 Not Cancer Driver No 32 0.152 0 0 0.0 0
HAO1 HAO1 Q9UJM8 2-Hydroxyacid oxidase 1 chr20 GO:0006979 Not Cancer Driver No 117 0.316 7 2 0.286 0
HBA2 HBA2 P69905 Hemoglobin subunit alpha chr16 GO:0006979 Not Cancer Driver No 9 0.063 4 0 0.0 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0006979 Not Cancer Driver No 45 0.306 7 2 0.286 5
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0006979 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0006979 Not Cancer Driver No 178 0.147 409 59 0.144 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0006979 Census Yes 118 0.143 435 51 0.117 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0006979 Not Cancer Driver No 46 0.16 81 13 0.16 0
HMOX2_ENST00000406590 HMOX2 P30519 Heme oxygenase 2 chr16 GO:0006979 Not Cancer Driver No 27 0.085 74 10 0.135 0
HP HP P00738 Haptoglobin chr16 GO:0006979 Not Cancer Driver No 39 0.096 57 2 0.035 1
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0006979 Not Cancer Driver No 59 0.112 335 37 0.11 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0006979 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0006979 Not Cancer Driver No 52 0.11 8 1 0.125 0
IDH1 IDH1 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic chr2 GO:0006979 Census, Compendium Yes 553 1.336 37 3 0.081 0
IL18BP_ENST00000337131 IL18BP O95998 Interleukin-18-binding protein chr11 GO:0006979 Not Cancer Driver No 16 0.082 50 6 0.12 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0006979 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0006979 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0006979 Not Cancer Driver No 49 0.153 84 12 0.143 0
IPCEF1_ENST00000265198 IPCEF1 Q8WWN9 Interactor protein for cytohesin exchange factors 1 chr6 GO:0006979 Not Cancer Driver No 53 0.121 293 31 0.106 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0006979 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUN JUN P05412 Transcription factor Jun chr1 GO:0006979 Census Yes 35 0.106 281 25 0.089 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0006979 Not Cancer Driver No 213 0.347 218 53 0.243 0
KDM6B_ENST00000448097 KDM6B O15054 Lysine-specific demethylase 6B chr17 GO:0006979 Not Cancer Driver No 189 0.115 1278 142 0.111 2
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0006979 Not Cancer Driver No 13 0.037 280 4 0.014 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0006979 Not Cancer Driver No 133 0.207 426 98 0.23 20
LIAS LIAS O43766 Lipoyl synthase, mitochondrial chr4 GO:0006979 Not Cancer Driver No 46 0.124 82 10 0.122 1
LPO LPO P22079 Lactoperoxidase chr17 GO:0006979 Not Cancer Driver No 127 0.178 99 17 0.172 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0006979 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP1LC3A_ENST00000397709 MAP1LC3A Q9H492 Microtubule-associated proteins 1A/1B light chain 3A chr20 GO:0006979 Not Cancer Driver No 22 0.182 24 1 0.042 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0006979 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0006979 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0006979 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0006979 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0006979 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0006979 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0006979 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0006979 Not Cancer Driver No 128 0.169 750 126 0.168 18
MBL2 MBL2 P11226 Mannose-binding protein C chr10 GO:0006979 Not Cancer Driver No 63 0.254 122 32 0.262 0
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0006979 Not Cancer Driver No 26 0.168 0 0 0.0 0
MICB MICB Q29980 MHC class I polypeptide-related sequence B chr6 GO:0006979 Not Cancer Driver No 56 0.146 175 22 0.126 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0006979 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0006979 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0006979 Not Cancer Driver No 129 0.182 124 26 0.21 0
MPO MPO P05164 Myeloperoxidase chr17 GO:0006979 Not Cancer Driver No 149 0.2 52 12 0.231 3
MPV17 MPV17 P39210 Protein Mpv17 chr2 GO:0006979 Not Cancer Driver No 21 0.119 0 0 0.0 16
MSRA MSRA Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase chr8 GO:0006979 Not Cancer Driver No 39 0.166 81 14 0.173 0
MSRB2 MSRB2 Q9Y3D2 Methionine-R-sulfoxide reductase B2, mitochondrial chr10 GO:0006979 Not Cancer Driver No 17 0.093 65 6 0.092 0
MSRB3 MSRB3 Q8IXL7 Methionine-R-sulfoxide reductase B3 chr12 GO:0006979 Not Cancer Driver No 49 0.255 42 14 0.333 1
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0006979 Not Cancer Driver No 115 0.153 553 76 0.137 0
NAPRT NAPRT Q6XQN6 Nicotinate phosphoribosyltransferase chr8 GO:0006979 Not Cancer Driver No 38 0.071 98 11 0.112 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0006979 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCOA7_ENST00000368357 NCOA7 Q8NI08 Nuclear receptor coactivator 7 chr6 GO:0006979 Not Cancer Driver No 110 0.117 538 63 0.117 0
NDUFA12 NDUFA12 Q9UI09 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 chr12 GO:0006979 Not Cancer Driver No 18 0.124 31 6 0.194 0
NDUFA6_ENST00000602404 NDUFA6 P56556 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 chr22 GO:0006979 Not Cancer Driver No 10 0.078 14 2 0.143 1
NDUFB4 NDUFB4 O95168 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 chr3 GO:0006979 Not Cancer Driver No 13 0.101 20 1 0.05 0
NDUFS2 NDUFS2 O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial chr1 GO:0006979 Not Cancer Driver No 58 0.125 49 5 0.102 4
NDUFS8 NDUFS8 O00217 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial chr11 GO:0006979 Not Cancer Driver No 27 0.129 37 2 0.054 3
NEIL1_ENST00000564784 NEIL1 Q96FI4 Endonuclease 8-like 1 chr15 GO:0006979 Not Cancer Driver No 41 0.105 165 14 0.085 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0006979 Not Cancer Driver No 60 0.101 294 37 0.126 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0006979 Census, Compendium Yes 228 0.377 402 62 0.154 4
NME8_ENST00000440017 NME8 Q8N427 Thioredoxin domain-containing protein 3 chr7 GO:0006979 Not Cancer Driver No 178 0.303 87 44 0.506 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0006979 Not Cancer Driver No 21 0.077 10 1 0.1 0
NUDT15 NUDT15 Q9NV35 Nucleotide triphosphate diphosphatase NUDT15 chr13 GO:0006979 Not Cancer Driver No 24 0.146 37 3 0.081 0
NUDT1_ENST00000397046 NUDT1 P36639 Oxidized purine nucleoside triphosphate hydrolase chr7 GO:0006979 Not Cancer Driver No 25 0.16 17 4 0.235 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006979 Not Cancer Driver No 37 0.107 71 12 0.169 0
OSER1 OSER1 Q9NX31 Oxidative stress-responsive serine-rich protein 1 chr20 GO:0006979 Not Cancer Driver No 32 0.11 221 28 0.127 0
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0006979 Not Cancer Driver No 126 0.144 544 76 0.14 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0006979 Not Cancer Driver No 69 0.131 208 29 0.139 0
PAGE4_ENST00000376141 PAGE4 O60829 P antigen family member 4 chrX GO:0006979 Not Cancer Driver No 20 0.196 102 20 0.196 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0006979 Not Cancer Driver No 11 0.058 30 0 0.0 5
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0006979 Not Cancer Driver No 62 0.149 296 48 0.162 23
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0006979 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0006979 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0006979 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0006979 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0006979 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0006979 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDLIM1 PDLIM1 O00151 PDZ and LIM domain protein 1 chr10 GO:0006979 Not Cancer Driver No 62 0.188 219 39 0.178 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0006979 Not Cancer Driver No 57 0.098 99 13 0.131 23
PJVK_ENST00000644580 PJVK Q0ZLH3 Pejvakin chr2 GO:0006979 Not Cancer Driver No 48 0.136 1 0 0.0 3
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0006979 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0006979 Not Cancer Driver No 61 0.151 191 32 0.168 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0006979 Not Cancer Driver No 75 0.116 202 15 0.074 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0006979 Not Cancer Driver No 53 0.102 177 23 0.13 4
PON2 PON2 Q15165 Serum paraoxonase/arylesterase 2 chr7 GO:0006979 Not Cancer Driver No 46 0.13 13 3 0.231 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0006979 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0006979 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0006979 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP2CB PPP2CB P62714 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform chr8 GO:0006979 Not Cancer Driver No 37 0.12 12 0 0.0 0
PRDX1_ENST00000319248 PRDX1 Q06830 Peroxiredoxin-1 chr1 GO:0006979 Not Cancer Driver No 22 0.111 40 5 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0006979 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0006979 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX4 PRDX4 Q13162 Peroxiredoxin-4 chrX GO:0006979 Not Cancer Driver No 36 0.133 29 2 0.069 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0006979 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0006979 Not Cancer Driver No 46 0.205 13 4 0.308 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0006979 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0006979 Compendium Yes 79 0.117 43 9 0.209 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0006979 Census Yes 201 0.22 189 33 0.175 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0006979 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0006979 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0006979 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSIP1_ENST00000380738 PSIP1 O75475 PC4 and SFRS1-interacting protein chr9 GO:0006979 Census, Compendium Yes 75 0.142 481 71 0.148 0
PSMB5 PSMB5 P28074 Proteasome subunit beta type-5 chr14 GO:0006979 Not Cancer Driver No 39 0.148 9 0 0.0 0
PTGS1 PTGS1 P23219 Prostaglandin G/H synthase 1 chr9 GO:0006979 Not Cancer Driver No 123 0.205 28 3 0.107 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0006979 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0006979 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0006979 Census, Compendium Yes 292 0.203 302 57 0.189 0
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0006979 Not Cancer Driver No 142 0.145 498 73 0.147 0
PXDN PXDN Q92626 Peroxidasin homolog chr2 GO:0006979 Not Cancer Driver No 332 0.224 307 77 0.251 1
PXDNL PXDNL A1KZ92 Probable oxidoreductase PXDNL chr8 GO:0006979 Not Cancer Driver No 554 0.379 397 171 0.431 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0006979 Not Cancer Driver No 62 0.105 341 24 0.07 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0006979 Not Cancer Driver No 23 0.117 87 11 0.126 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0006979 Not Cancer Driver No 10 0.093 18 1 0.056 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:0006979 Not Cancer Driver No 26 0.103 104 7 0.067 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0006979 Compendium Yes 75 0.136 400 48 0.12 0
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0006979 Not Cancer Driver No 57 0.101 309 37 0.12 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0006979 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0006979 Compendium Yes 82 0.122 277 39 0.141 4
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0006979 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0006979 Not Cancer Driver No 86 0.136 168 26 0.155 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0006979 Not Cancer Driver No 9 0.114 0 0 0.0 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0006979 Not Cancer Driver No 22 0.091 48 4 0.083 0
RRM2B RRM2B Q7LG56 Ribonucleoside-diphosphate reductase subunit M2 B chr8 GO:0006979 Not Cancer Driver No 46 0.131 32 5 0.156 9
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0006979 Census Yes 39 0.386 28 14 0.5 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 GO:0006979 Not Cancer Driver No 80 0.132 230 29 0.126 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0006979 Not Cancer Driver No 12 0.132 14 2 0.143 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0006979 Not Cancer Driver No 31 0.1 259 30 0.116 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0006979 Not Cancer Driver No 10 0.106 47 6 0.128 0
SELENOP_ENST00000506577 SELENOP P49908 Selenoprotein P chr5 GO:0006979 Not Cancer Driver No 67 0.176 154 19 0.123 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0006979 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SGK2_ENST00000373100 SGK2 Q9HBY8 Serine/threonine-protein kinase Sgk2 chr20 GO:0006979 Not Cancer Driver No 84 0.229 52 10 0.192 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0006979 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0006979 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC23A2 SLC23A2 Q9UGH3 Solute carrier family 23 member 2 chr20 GO:0006979 Not Cancer Driver No 87 0.134 76 8 0.105 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0006979 Not Cancer Driver No 305 0.313 158 48 0.304 0
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0006979 Not Cancer Driver No 92 0.14 224 29 0.129 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0006979 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0006979 Not Cancer Driver No 32 0.144 25 5 0.2 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0006979 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0006979 Not Cancer Driver No 47 0.122 25 2 0.08 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0006979 Census Yes 53 0.099 130 11 0.085 1
SRXN1 SRXN1 Q9BYN0 Sulfiredoxin-1 chr20 GO:0006979 Not Cancer Driver No 15 0.109 48 2 0.042 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0006979 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0006979 Census, Compendium Yes 106 0.125 325 44 0.135 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0006979 Not Cancer Driver No 71 0.235 112 29 0.259 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0006979 Not Cancer Driver No 67 0.151 118 16 0.136 0
STK25 STK25 O00506 Serine/threonine-protein kinase 25 chr2 GO:0006979 Not Cancer Driver No 42 0.099 170 15 0.088 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0006979 Not Cancer Driver No 62 0.149 119 18 0.151 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0006979 Not Cancer Driver No 69 0.17 28 2 0.071 0
TAT TAT P17735 Tyrosine aminotransferase chr16 GO:0006979 Not Cancer Driver No 102 0.225 75 21 0.28 1
THG1L THG1L Q9NWX6 Probable tRNA(His) guanylyltransferase chr5 GO:0006979 Not Cancer Driver No 32 0.107 22 2 0.091 1
TLDC2_ENST00000602922 TLDC2 A0PJX2 TLD domain-containing protein 2 chr20 GO:0006979 Not Cancer Driver No 39 0.181 43 8 0.186 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0006979 Census, Compendium Yes 98 0.124 231 33 0.143 1
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0006979 Not Cancer Driver No 33 0.099 0 0 0.0 3
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0006979 Not Cancer Driver No 32 0.133 134 20 0.149 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0006979 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPO TPO P07202 Thyroid peroxidase chr2 GO:0006979 Not Cancer Driver No 326 0.349 163 69 0.423 24
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006979 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0006979 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0006979 Not Cancer Driver No 286 0.19 266 44 0.165 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0006979 Not Cancer Driver No 22 0.133 34 4 0.118 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0006979 Not Cancer Driver No 61 0.156 77 14 0.182 0
TXNRD2 TXNRD2 Q9NNW7 Thioredoxin reductase 2, mitochondrial chr22 GO:0006979 Not Cancer Driver No 70 0.134 46 6 0.13 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0006979 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCN UCN P55089 Urocortin chr2 GO:0006979 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0006979 Not Cancer Driver No 43 0.14 1 0 0.0 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0006979 Not Cancer Driver No 31 0.1 11 3 0.273 0
UCP3 UCP3 P55916 Mitochondrial uncoupling protein 3 chr11 GO:0006979 Not Cancer Driver No 37 0.119 7 1 0.143 1
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0006979 Not Cancer Driver No 88 0.172 20 5 0.25 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0006979 Census, Compendium Yes 164 0.115 373 41 0.11 2
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006979 Not Cancer Driver No 85 0.134 426 53 0.124 1
ZNF277 ZNF277 Q9NRM2 Zinc finger protein 277 chr7 GO:0006979 Not Cancer Driver No 59 0.131 79 15 0.19 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0006979 Not Cancer Driver No 8 0.047 153 8 0.052 0