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Total number of protein in "GO:2000112" GO term:  410

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AARS AARS1 P49588 Alanine--tRNA ligase, cytoplasmic chr16 GO:2000112 Not Cancer Driver No 97 0.1 140 14 0.1 5
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:2000112 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:2000112 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:2000112 Not Cancer Driver No 103 0.14 47 0 0.0 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:2000112 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:2000112 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACOT8 ACOT8 O14734 Acyl-coenzyme A thioesterase 8 chr20 GO:2000112 Not Cancer Driver No 43 0.135 52 7 0.135 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:2000112 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:2000112 Not Cancer Driver No 39 0.16 92 21 0.228 1
AGO1 AGO1 Q9UL18 Protein argonaute-1 chr1 GO:2000112 Not Cancer Driver No 126 0.147 87 11 0.126 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:2000112 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGO3 AGO3 Q9H9G7 Protein argonaute-3 chr1 GO:2000112 Not Cancer Driver No 110 0.128 143 19 0.133 0
AGO4 AGO4 Q9HCK5 Protein argonaute-4 chr1 GO:2000112 Not Cancer Driver No 100 0.116 183 24 0.131 0
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:2000112 Not Cancer Driver No 56 0.283 0 0 0.0 8
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:2000112 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:2000112 Census Yes 77 0.16 84 9 0.107 2
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:2000112 Not Cancer Driver No 90 0.19 0 0 0.0 0
ALKBH1 ALKBH1 Q13686 Nucleic acid dioxygenase ALKBH1 chr14 GO:2000112 Not Cancer Driver No 55 0.141 77 11 0.143 0
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:2000112 Not Cancer Driver No 52 0.163 83 13 0.157 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:2000112 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:2000112 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:2000112 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATG101 ATG101 Q9BSB4 Autophagy-related protein 101 chr12 GO:2000112 Not Cancer Driver No 21 0.096 5 0 0.0 0
ATG13_ENST00000359513 ATG13 O75143 Autophagy-related protein 13 chr11 GO:2000112 Not Cancer Driver No 55 0.106 205 27 0.132 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:2000112 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:2000112 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:2000112 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:2000112 Not Cancer Driver No 51 0.148 63 8 0.127 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:2000112 Not Cancer Driver No 61 0.118 23 2 0.087 0
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:2000112 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:2000112 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:2000112 Census, Compendium Yes 134 0.19 328 67 0.204 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:2000112 Census Yes 153 0.108 667 70 0.105 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:2000112 Compendium Yes 141 0.136 601 70 0.116 19
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:2000112 Census, Compendium Yes 457 0.134 1542 225 0.146 46
C19orf66 SHFL Q9NUL5 Shiftless antiviral inhibitor of ribosomal frameshifting protein chr19 GO:2000112 Not Cancer Driver No 23 0.079 166 12 0.072 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:2000112 Not Cancer Driver No 14 0.05 103 6 0.058 2
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:2000112 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:2000112 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:2000112 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:2000112 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:2000112 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:2000112 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:2000112 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:2000112 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:2000112 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:2000112 Not Cancer Driver No 41 0.075 36 2 0.056 0
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:2000112 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:2000112 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:2000112 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:2000112 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:2000112 Not Cancer Driver No 60 0.11 377 35 0.093 5
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:2000112 Not Cancer Driver No 56 0.115 166 17 0.102 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:2000112 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:2000112 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:2000112 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:2000112 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:2000112 Not Cancer Driver No 13 0.107 7 0 0.0 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:2000112 Not Cancer Driver No 93 0.104 708 83 0.117 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:2000112 Census Yes 11 0.062 19 0 0.0 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:2000112 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:2000112 Not Cancer Driver No 31 0.109 21 1 0.048 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:2000112 Not Cancer Driver No 4 0.038 57 3 0.053 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:2000112 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB2_ENST00000507071 CPEB2 Q7Z5Q1 Cytoplasmic polyadenylation element-binding protein 2 chr4 GO:2000112 Not Cancer Driver No 66 0.112 269 17 0.063 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:2000112 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:2000112 Not Cancer Driver No 85 0.117 443 54 0.122 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:2000112 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:2000112 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:2000112 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:2000112 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:2000112 Not Cancer Driver No 61 0.112 31 3 0.097 40
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:2000112 Not Cancer Driver No 157 0.207 641 134 0.209 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 GO:2000112 Not Cancer Driver No 75 0.111 333 26 0.078 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:2000112 Not Cancer Driver No 68 0.111 311 22 0.071 0
DBI_ENST00000355857 DBI P07108 Acyl-CoA-binding protein chr2 GO:2000112 Not Cancer Driver No 13 0.149 27 6 0.222 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:2000112 Not Cancer Driver No 57 0.136 167 24 0.144 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:2000112 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX6 DDX6 P26196 Probable ATP-dependent RNA helicase DDX6 chr11 GO:2000112 Census, Compendium Yes 44 0.091 129 7 0.054 5
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:2000112 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:2000112 Compendium Yes 182 0.143 331 42 0.127 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:2000112 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:2000112 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:2000112 Not Cancer Driver No 62 0.121 145 29 0.2 24
DNAJC2 DNAJC2 Q99543 DnaJ homolog subfamily C member 2 chr7 GO:2000112 Not Cancer Driver No 67 0.108 425 48 0.113 0
DNAJC24 DNAJC24 Q6P3W2 DnaJ homolog subfamily C member 24 chr11 GO:2000112 Not Cancer Driver No 18 0.121 11 0 0.0 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:2000112 Not Cancer Driver No 60 0.119 131 17 0.13 0
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:2000112 Not Cancer Driver No 23 0.065 36 0 0.0 0
DONSON DONSON Q9NYP3 Protein downstream neighbor of Son chr21 GO:2000112 Not Cancer Driver No 50 0.088 217 13 0.06 6
DPH1 DPH1 Q9BZG8 2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 chr17 GO:2000112 Not Cancer Driver No 41 0.093 67 8 0.119 2
DPH2 DPH2 Q9BQC3 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 chr1 GO:2000112 Not Cancer Driver No 77 0.157 177 26 0.147 0
DPH3 DPH3 Q96FX2 DPH3 homolog chr3 GO:2000112 Not Cancer Driver No 12 0.146 0 0 0.0 0
DPH5 DPH5 Q9H2P9 Diphthine methyl ester synthase chr1 GO:2000112 Not Cancer Driver No 25 0.088 18 1 0.056 0
DPH6 DPH6 Q7L8W6 Diphthine--ammonia ligase chr15 GO:2000112 Not Cancer Driver No 29 0.109 0 0 0.0 0
DPH7 DPH7 Q9BTV6 Diphthine methyltransferase chr9 GO:2000112 Not Cancer Driver No 38 0.084 107 10 0.093 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:2000112 Not Cancer Driver No 28 0.071 41 4 0.098 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:2000112 Not Cancer Driver No 77 0.128 294 39 0.133 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:2000112 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:2000112 Not Cancer Driver No 132 0.152 582 85 0.146 0
EEFSEC EEFSEC P57772 Selenocysteine-specific elongation factor chr3 GO:2000112 Not Cancer Driver No 80 0.134 124 21 0.169 0
EIF2AK1 EIF2AK1 Q9BQI3 Eukaryotic translation initiation factor 2-alpha kinase 1 chr7 GO:2000112 Not Cancer Driver No 87 0.138 238 29 0.122 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:2000112 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:2000112 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:2000112 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:2000112 Not Cancer Driver No 35 0.111 59 6 0.102 0
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:2000112 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:2000112 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF3E EIF3E P60228 Eukaryotic translation initiation factor 3 subunit E chr8 GO:2000112 Census, Compendium Yes 73 0.164 27 1 0.037 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:2000112 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E2 EIF4E2 O60573 Eukaryotic translation initiation factor 4E type 2 chr2 GO:2000112 Not Cancer Driver No 27 0.11 80 5 0.062 0
EIF4EBP1 EIF4EBP1 Q13541 Eukaryotic translation initiation factor 4E-binding protein 1 chr8 GO:2000112 Not Cancer Driver No 8 0.068 118 8 0.068 0
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 GO:2000112 Not Cancer Driver No 17 0.142 118 14 0.119 0
EIF4EBP3 EIF4EBP3 O60516 Eukaryotic translation initiation factor 4E-binding protein 3 chr5 GO:2000112 Not Cancer Driver No 9 0.09 78 6 0.077 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:2000112 Not Cancer Driver No 116 0.118 899 101 0.112 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:2000112 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:2000112 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:2000112 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:2000112 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:2000112 Not Cancer Driver No 37 0.24 21 5 0.238 5
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:2000112 Not Cancer Driver No 30 0.122 17 3 0.176 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:2000112 Not Cancer Driver No 118 0.306 117 34 0.291 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:2000112 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:2000112 Not Cancer Driver No 148 0.16 101 5 0.05 33
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:2000112 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:2000112 Census Yes 120 0.131 225 27 0.12 15
ETF1 ETF1 P62495 Eukaryotic peptide chain release factor subunit 1 chr5 GO:2000112 Not Cancer Driver No 60 0.137 28 11 0.393 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:2000112 Not Cancer Driver No 87 0.098 375 35 0.093 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:2000112 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:2000112 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:2000112 Not Cancer Driver No 58 0.132 154 18 0.117 1
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:2000112 Not Cancer Driver No 99 0.133 206 20 0.097 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:2000112 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:2000112 Not Cancer Driver No 106 0.16 6 1 0.167 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:2000112 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:2000112 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:2000112 Not Cancer Driver No 48 0.107 113 13 0.115 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:2000112 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:2000112 Census, Compendium Yes 113 0.141 162 28 0.173 0
FKTN_ENST00000602661 FKTN O75072 Ribitol-5-phosphate transferase FKTN chr9 GO:2000112 Not Cancer Driver No 51 0.111 0 0 0.0 10
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:2000112 Not Cancer Driver No 124 0.196 327 70 0.214 3
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:2000112 Not Cancer Driver No 67 0.133 53 10 0.189 3
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:2000112 Census, Compendium Yes 68 0.165 242 41 0.169 5
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:2000112 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:2000112 Not Cancer Driver No 88 0.189 73 14 0.192 107
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:2000112 Not Cancer Driver No 10 0.049 97 4 0.041 1
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:2000112 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:2000112 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:2000112 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:2000112 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:2000112 Not Cancer Driver No 32 0.143 77 14 0.182 0
GLE1 GLE1 Q53GS7 mRNA export factor GLE1 chr9 GO:2000112 Not Cancer Driver No 64 0.092 299 29 0.097 3
GMNN_ENST00000620958 GMNN O75496 Geminin chr6 GO:2000112 Not Cancer Driver No 24 0.115 206 24 0.117 1
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:2000112 Not Cancer Driver No 120 0.206 242 43 0.178 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:2000112 Not Cancer Driver No 115 0.115 854 96 0.112 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:2000112 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:2000112 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:2000112 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:2000112 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:2000112 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSPT1_ENST00000563468 GSPT1 P15170 Eukaryotic peptide chain release factor GTP-binding subunit ERF3A chr16 GO:2000112 Not Cancer Driver No 42 0.084 149 13 0.087 0
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:2000112 Not Cancer Driver No 16 0.077 63 3 0.048 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:2000112 Compendium Yes 233 0.32 43 16 0.372 0
HHATL HHATL Q9HCP6 Protein-cysteine N-palmitoyltransferase HHAT-like protein chr3 GO:2000112 Not Cancer Driver No 71 0.141 14 2 0.143 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:2000112 Not Cancer Driver No 55 0.131 319 41 0.129 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:2000112 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:2000112 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:2000112 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:2000112 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:2000112 Not Cancer Driver No 77 0.093 504 45 0.089 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:2000112 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:2000112 Census, Compendium Yes 100 0.138 254 43 0.169 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:2000112 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:2000112 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:2000112 Not Cancer Driver No 39 0.217 44 12 0.273 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:2000112 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:2000112 Not Cancer Driver No 47 0.174 47 8 0.17 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:2000112 Not Cancer Driver No 49 0.153 84 12 0.143 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:2000112 Not Cancer Driver No 31 0.124 108 15 0.139 0
ING5_ENST00000313552 ING5 Q8WYH8 Inhibitor of growth protein 5 chr2 GO:2000112 Not Cancer Driver No 25 0.104 119 9 0.076 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:2000112 Compendium Yes 173 0.111 682 76 0.111 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:2000112 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:2000112 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:2000112 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:2000112 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:2000112 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITM2A ITM2A O43736 Integral membrane protein 2A chrX GO:2000112 Not Cancer Driver No 75 0.285 26 9 0.346 0
ITM2B ITM2B Q9Y287 Integral membrane protein 2B chr13 GO:2000112 Not Cancer Driver No 21 0.079 12 0 0.0 1
ITM2C ITM2C Q9NQX7 Integral membrane protein 2C chr2 GO:2000112 Not Cancer Driver No 31 0.116 33 4 0.121 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 GO:2000112 Not Cancer Driver No 94 0.112 409 47 0.115 0
JADE2_ENST00000395003 JADE2 Q9NQC1 E3 ubiquitin-protein ligase Jade-2 chr5 GO:2000112 Not Cancer Driver No 91 0.115 427 50 0.117 0
JADE3_ENST00000611250 JADE3 Q92613 Protein Jade-3 chrX GO:2000112 Not Cancer Driver No 110 0.134 421 52 0.124 0
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:2000112 Census, Compendium Yes 167 0.149 63 10 0.159 7
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:2000112 Not Cancer Driver No 67 0.145 19 5 0.263 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:2000112 Census Yes 97 0.159 327 47 0.144 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:2000112 Not Cancer Driver No 109 0.256 40 10 0.25 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:2000112 Not Cancer Driver No 84 0.118 684 81 0.118 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:2000112 Compendium Yes 56 0.136 177 29 0.164 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:2000112 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:2000112 Not Cancer Driver No 37 0.177 86 12 0.14 0
LRPPRC LRPPRC P42704 Leucine-rich PPR motif-containing protein, mitochondrial chr2 GO:2000112 Not Cancer Driver No 131 0.094 18 2 0.111 1
MALSU1 MALSU1 Q96EH3 Mitochondrial assembly of ribosomal large subunit protein 1 chr7 GO:2000112 Not Cancer Driver No 17 0.073 34 0 0.0 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:2000112 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:2000112 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:2000112 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:2000112 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:2000112 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:2000112 Not Cancer Driver No 51 0.108 101 12 0.119 0
MCIDAS MCIDAS D6RGH6 Multicilin chr5 GO:2000112 Not Cancer Driver No 4 0.01 269 4 0.015 2
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:2000112 Not Cancer Driver No 22 0.115 171 21 0.123 0
MEN1 MEN1 O00255 Menin chr11 GO:2000112 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:2000112 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:2000112 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:2000112 Not Cancer Driver No 74 0.128 274 29 0.106 0
METTL4 METTL4 Q8N3J2 N(6)-adenine-specific methyltransferase METTL4 chr18 GO:2000112 Not Cancer Driver No 61 0.129 34 4 0.118 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:2000112 Not Cancer Driver No 35 0.054 501 24 0.048 0
MGAT4D MGAT4D A6NG13 Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D chr4 GO:2000112 Not Cancer Driver No 8 0.021 14 0 0.0 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:2000112 Not Cancer Driver No 110 0.11 101 8 0.079 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:2000112 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:2000112 Not Cancer Driver No 46 0.111 51 7 0.137 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:2000112 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTG1 MTG1 Q9BT17 Mitochondrial ribosome-associated GTPase 1 chr10 GO:2000112 Not Cancer Driver No 43 0.129 16 3 0.188 0
MTG2 MTG2 Q9H4K7 Mitochondrial ribosome-associated GTPase 2 chr20 GO:2000112 Not Cancer Driver No 57 0.14 47 9 0.191 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:2000112 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTRF1 MTRF1 O75570 Peptide chain release factor 1, mitochondrial chr13 GO:2000112 Not Cancer Driver No 50 0.112 71 9 0.127 0
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:2000112 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:2000112 Census, Compendium Yes 80 0.182 299 46 0.154 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:2000112 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:2000112 Not Cancer Driver No 61 0.123 386 44 0.114 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:2000112 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:2000112 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:2000112 Not Cancer Driver No 31 0.179 117 25 0.214 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:2000112 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBN NBN O60934 Nibrin chr8 GO:2000112 Census Yes 90 0.119 417 54 0.129 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:2000112 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:2000112 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:2000112 Not Cancer Driver No 94 0.133 72 11 0.153 1
NECAB1 NECAB1 Q8N987 N-terminal EF-hand calcium-binding protein 1 chr8 GO:2000112 Not Cancer Driver No 54 0.154 135 21 0.156 0
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:2000112 Not Cancer Driver No 46 0.119 122 9 0.074 0
NECAB3 NECAB3 Q96P71 N-terminal EF-hand calcium-binding protein 3 chr20 GO:2000112 Not Cancer Driver No 39 0.098 169 17 0.101 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:2000112 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:2000112 Not Cancer Driver No 35 0.116 23 0 0.0 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:2000112 Not Cancer Driver No 26 0.089 215 21 0.098 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:2000112 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:2000112 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:2000112 Not Cancer Driver No 10 0.079 82 6 0.073 0
NSUN3 NSUN3 Q9H649 tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial chr3 GO:2000112 Not Cancer Driver No 34 0.1 0 0 0.0 0
NUGGC NUGGC Q68CJ6 Nuclear GTPase SLIP-GC chr8 GO:2000112 Not Cancer Driver No 143 0.18 141 21 0.149 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:2000112 Not Cancer Driver No 90 0.105 267 31 0.116 0
OGFOD1 OGFOD1 Q8N543 Prolyl 3-hydroxylase OGFOD1 chr16 GO:2000112 Not Cancer Driver No 44 0.081 156 6 0.038 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:2000112 Census, Compendium Yes 100 0.157 317 55 0.174 0
PADI6 PADI6 Q6TGC4 Protein-arginine deiminase type-6 chr1 GO:2000112 Not Cancer Driver No 101 0.146 27 5 0.185 2
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:2000112 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAIP2B PAIP2B Q9ULR5 Polyadenylate-binding protein-interacting protein 2B chr2 GO:2000112 Not Cancer Driver No 16 0.13 123 16 0.13 0
PAIP2_ENST00000265192 PAIP2 Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 chr5 GO:2000112 Not Cancer Driver No 11 0.087 88 10 0.114 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:2000112 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:2000112 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:2000112 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:2000112 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:2000112 Compendium Yes 218 0.126 325 40 0.123 0
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:2000112 Not Cancer Driver No 181 0.137 412 62 0.15 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:2000112 Not Cancer Driver No 35 0.103 327 33 0.101 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:2000112 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:2000112 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:2000112 Census Yes 37 0.154 99 22 0.222 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:2000112 Census, Compendium Yes 164 0.148 231 44 0.19 7
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:2000112 Census Yes 160 0.124 948 116 0.122 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:2000112 Not Cancer Driver No 166 0.132 782 101 0.129 1
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:2000112 Not Cancer Driver No 54 0.084 209 11 0.053 0
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:2000112 Not Cancer Driver No 66 0.201 328 66 0.201 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:2000112 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:2000112 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:2000112 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:2000112 Not Cancer Driver No 59 0.097 369 37 0.1 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:2000112 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:2000112 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:2000112 Not Cancer Driver No 64 0.132 46 4 0.087 3
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 GO:2000112 Not Cancer Driver No 75 0.1 55 5 0.091 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 GO:2000112 Not Cancer Driver No 84 0.112 60 3 0.05 15
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:2000112 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:2000112 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:2000112 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:2000112 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:2000112 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 GO:2000112 Not Cancer Driver No 430 0.383 807 334 0.414 1
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:2000112 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 GO:2000112 Not Cancer Driver No 37 0.117 16 0 0.0 0
PPP1R3D PPP1R3D O95685 Protein phosphatase 1 regulatory subunit 3D chr20 GO:2000112 Not Cancer Driver No 36 0.12 94 8 0.085 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:2000112 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:2000112 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:2000112 Not Cancer Driver No 14 0.039 198 11 0.056 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:2000112 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:2000112 Compendium Yes 118 0.134 246 34 0.138 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:2000112 Not Cancer Driver No 50 0.135 18 1 0.056 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:2000112 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTH PTH P01270 Parathyroid hormone chr11 GO:2000112 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:2000112 Not Cancer Driver No 161 0.16 261 37 0.142 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:2000112 Not Cancer Driver No 150 0.126 640 77 0.12 3
PXYLP1 PXYLP1 Q8TE99 2-phosphoxylose phosphatase 1 chr3 GO:2000112 Not Cancer Driver No 63 0.131 32 13 0.406 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:2000112 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:2000112 Not Cancer Driver No 168 0.121 143 17 0.119 2
RABL3 RABL3 Q5HYI8 Rab-like protein 3 chr3 GO:2000112 Not Cancer Driver No 37 0.157 1 0 0.0 1
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:2000112 Not Cancer Driver No 16 0.108 0 0 0.0 0
RB1CC1 RB1CC1 Q8TDY2 RB1-inducible coiled-coil protein 1 chr8 GO:2000112 Not Cancer Driver No 202 0.127 578 75 0.13 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:2000112 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:2000112 Not Cancer Driver No 40 0.11 129 12 0.093 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:2000112 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:2000112 Not Cancer Driver No 19 0.041 87 7 0.08 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:2000112 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:2000112 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:2000112 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:2000112 Not Cancer Driver No 38 0.112 20 1 0.05 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:2000112 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGN RGN Q15493 Regucalcin chrX GO:2000112 Not Cancer Driver No 38 0.127 14 3 0.214 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:2000112 Not Cancer Driver No 20 0.146 3 0 0.0 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:2000112 Not Cancer Driver No 46 0.102 83 11 0.133 1
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:2000112 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:2000112 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPL13A RPL13A P40429 60S ribosomal protein L13a chr19 GO:2000112 Not Cancer Driver No 27 0.133 33 2 0.061 0
RPL22 RPL22 P35268 60S ribosomal protein L22 chr1 GO:2000112 Census, Compendium Yes 26 0.203 15 1 0.067 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:2000112 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:2000112 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:2000112 Compendium Yes 106 0.143 145 18 0.124 13
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:2000112 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:2000112 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:2000112 Not Cancer Driver No 54 0.143 97 15 0.155 0
SECISBP2 SECISBP2 Q96T21 Selenocysteine insertion sequence-binding protein 2 chr9 GO:2000112 Not Cancer Driver No 90 0.105 565 50 0.088 1
SECISBP2L SECISBP2L Q93073 Selenocysteine insertion sequence-binding protein 2-like chr15 GO:2000112 Not Cancer Driver No 142 0.129 871 111 0.127 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:2000112 Not Cancer Driver No 7 0.037 122 6 0.049 0
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:2000112 Not Cancer Driver No 25 0.128 0 0 0.0 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:2000112 Not Cancer Driver No 73 0.124 285 38 0.133 0
SEPSECS SEPSECS Q9HD40 O-phosphoseryl-tRNA(Sec) selenium transferase chr4 GO:2000112 Not Cancer Driver No 47 0.094 22 7 0.318 3
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:2000112 Not Cancer Driver No 74 0.154 147 26 0.177 0
SHMT2 SHMT2 P34897 Serine hydroxymethyltransferase, mitochondrial chr12 GO:2000112 Not Cancer Driver No 57 0.113 58 5 0.086 1
SLC25A37 SLC25A37 Q9NYZ2 Mitoferrin-1 chr8 GO:2000112 Not Cancer Driver No 45 0.133 68 5 0.074 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:2000112 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:2000112 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:2000112 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:2000112 Not Cancer Driver No 177 0.196 34 8 0.235 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:2000112 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:2000112 Not Cancer Driver No 166 0.117 751 97 0.129 0
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:2000112 Not Cancer Driver No 82 0.184 216 52 0.241 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:2000112 Not Cancer Driver No 73 0.133 49 4 0.082 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:2000112 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:2000112 Census Yes 53 0.099 130 11 0.085 1
SRP9 SRP9 P49458 Signal recognition particle 9 kDa protein chr1 GO:2000112 Not Cancer Driver No 14 0.163 4 1 0.25 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:2000112 Not Cancer Driver No 27 0.182 0 0 0.0 6
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:2000112 Census, Compendium Yes 110 0.143 152 15 0.099 19
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:2000112 Not Cancer Driver No 41 0.111 27 2 0.074 2
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:2000112 Not Cancer Driver No 40 0.112 117 9 0.077 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:2000112 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:2000112 Not Cancer Driver No 93 0.149 285 39 0.137 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 GO:2000112 Not Cancer Driver No 21 0.071 111 2 0.018 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:2000112 Not Cancer Driver No 51 0.123 202 15 0.074 27
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:2000112 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:2000112 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:2000112 Not Cancer Driver No 6 0.049 8 4 0.5 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:2000112 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:2000112 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:2000112 Not Cancer Driver No 33 0.061 361 20 0.055 0
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:2000112 Not Cancer Driver No 82 0.2 245 47 0.192 0
TICRR TICRR Q7Z2Z1 Treslin chr15 GO:2000112 Not Cancer Driver No 201 0.105 1308 129 0.099 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:2000112 Not Cancer Driver No 154 0.127 367 51 0.139 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:2000112 Not Cancer Driver No 38 0.084 190 17 0.089 4
TIPIN TIPIN Q9BVW5 TIMELESS-interacting protein chr15 GO:2000112 Not Cancer Driver No 26 0.086 242 19 0.079 0
TM9SF2 TM9SF2 Q99805 Transmembrane 9 superfamily member 2 chr13 GO:2000112 Not Cancer Driver No 82 0.124 16 2 0.125 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:2000112 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 GO:2000112 Not Cancer Driver No 39 0.121 26 3 0.115 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:2000112 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:2000112 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:2000112 Not Cancer Driver No 117 0.1 255 24 0.094 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:2000112 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:2000112 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:2000112 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:2000112 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:2000112 Not Cancer Driver No 51 0.107 268 29 0.108 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:2000112 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:2000112 Census Yes 311 0.132 1990 266 0.134 0
TRAP1 TRAP1 Q12931 Heat shock protein 75 kDa, mitochondrial chr16 GO:2000112 Not Cancer Driver No 74 0.105 110 11 0.1 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:2000112 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:2000112 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRNAU1AP TRNAU1AP Q9NX07 tRNA selenocysteine 1-associated protein 1 chr1 GO:2000112 Not Cancer Driver No 28 0.098 32 4 0.125 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:2000112 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSFM_ENST00000454289 TSFM P43897 Elongation factor Ts, mitochondrial chr12 GO:2000112 Not Cancer Driver No 37 0.114 74 7 0.095 2
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:2000112 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:2000112 Not Cancer Driver No 159 0.106 659 74 0.112 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:2000112 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNK UNK Q9C0B0 RING finger protein unkempt homolog chr17 GO:2000112 Not Cancer Driver No 79 0.098 511 46 0.09 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:2000112 Not Cancer Driver No 146 0.129 329 36 0.109 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:2000112 Not Cancer Driver No 10 0.079 41 1 0.024 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:2000112 Not Cancer Driver No 98 0.119 394 42 0.107 0
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:2000112 Not Cancer Driver No 66 0.12 232 29 0.125 4
WRNIP1 WRNIP1 Q96S55 ATPase WRNIP1 chr6 GO:2000112 Not Cancer Driver No 50 0.075 292 7 0.024 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:2000112 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:2000112 Not Cancer Driver No 213 0.125 577 65 0.113 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:2000112 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX2 YBX2 Q9Y2T7 Y-box-binding protein 2 chr17 GO:2000112 Not Cancer Driver No 48 0.132 342 46 0.135 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:2000112 Not Cancer Driver No 49 0.132 359 47 0.131 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:2000112 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:2000112 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:2000112 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:2000112 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:2000112 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:2000112 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:2000112 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:2000112 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:2000112 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:2000112 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:2000112 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF830 ZNF830 Q96NB3 Zinc finger protein 830 chr17 GO:2000112 Not Cancer Driver No 39 0.105 312 37 0.119 0
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:2000112 Not Cancer Driver No 126 0.117 261 31 0.119 0