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Total number of protein in "GO:1903706" GO term:  353

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:1903706 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:1903706 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:1903706 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:1903706 Census Yes 114 0.226 0 0 0.0 0
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:1903706 Census, Compendium Yes 98 0.191 56 6 0.107 0
ADA ADA P00813 Adenosine deaminase chr20 GO:1903706 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:1903706 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:1903706 Not Cancer Driver No 39 0.16 92 21 0.228 1
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:1903706 Not Cancer Driver No 31 0.077 297 21 0.071 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:1903706 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANKRD54 ANKRD54 Q6NXT1 Ankyrin repeat domain-containing protein 54 chr22 GO:1903706 Not Cancer Driver No 26 0.087 188 12 0.064 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:1903706 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:1903706 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:1903706 Not Cancer Driver No 138 0.12 404 59 0.146 0
APCS APCS P02743 Serum amyloid P-component chr1 GO:1903706 Not Cancer Driver No 73 0.327 0 0 0.0 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:1903706 Census Yes 77 0.098 511 56 0.11 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:1903706 Not Cancer Driver No 168 0.188 341 64 0.188 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:1903706 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:1903706 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:1903706 Census, Compendium Yes 134 0.19 328 67 0.204 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:1903706 Not Cancer Driver No 13 0.13 21 2 0.095 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:1903706 Not Cancer Driver No 86 0.211 142 26 0.183 5
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 GO:1903706 Not Cancer Driver No 171 0.162 425 68 0.16 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:1903706 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:1903706 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QC C1QC P02747 Complement C1q subcomponent subunit C chr1 GO:1903706 Not Cancer Driver No 46 0.188 134 26 0.194 1
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:1903706 Not Cancer Driver No 101 0.214 127 30 0.236 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:1903706 Census, Compendium Yes 303 0.263 530 140 0.264 5
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:1903706 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:1903706 Census, Compendium Yes 142 0.296 106 12 0.113 1
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:1903706 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:1903706 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:1903706 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:1903706 Not Cancer Driver No 81 0.217 23 1 0.043 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:1903706 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD27 CD27 P26842 CD27 antigen chr12 GO:1903706 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:1903706 Census Yes 42 0.191 18 10 0.556 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:1903706 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:1903706 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:1903706 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:1903706 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:1903706 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:1903706 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:1903706 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDK6 CDK6 Q00534 Cyclin-dependent kinase 6 chr7 GO:1903706 Census Yes 40 0.123 24 3 0.125 1
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:1903706 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:1903706 Not Cancer Driver No 3 0.009 276 2 0.007 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:1903706 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLDN18 CLDN18 P56856 Claudin-18 chr3 GO:1903706 Not Cancer Driver No 44 0.169 21 5 0.238 0
CLPTM1 CLPTM1 O96005 Cleft lip and palate transmembrane protein 1 chr19 GO:1903706 Not Cancer Driver No 83 0.124 163 19 0.117 0
CNOT4_ENST00000315544 CNOT4 O95628 CCR4-NOT transcription complex subunit 4 chr7 GO:1903706 Not Cancer Driver No 73 0.127 359 35 0.097 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:1903706 Compendium Yes 383 0.188 151 42 0.278 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:1903706 Census Yes 25 0.076 277 23 0.083 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:1903706 Not Cancer Driver No 64 0.163 135 14 0.104 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:1903706 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:1903706 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSF3R_ENST00000361632 CSF3R Q99062 Granulocyte colony-stimulating factor receptor chr1 GO:1903706 Census, Compendium Yes 131 0.157 209 34 0.163 2
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:1903706 Not Cancer Driver No 37 0.166 3 0 0.0 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:1903706 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:1903706 Not Cancer Driver No 8 0.099 64 7 0.109 0
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:1903706 Not Cancer Driver No 164 0.14 385 48 0.125 0
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:1903706 Not Cancer Driver No 64 0.084 102 2 0.02 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:1903706 Not Cancer Driver No 113 0.221 10 3 0.3 2
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:1903706 Compendium Yes 150 0.319 6 3 0.5 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:1903706 Not Cancer Driver No 115 0.159 145 24 0.166 1
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:1903706 Census, Compendium Yes 175 0.127 682 100 0.147 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:1903706 Not Cancer Driver No 81 0.168 135 24 0.178 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:1903706 Not Cancer Driver No 60 0.155 252 46 0.183 0
EIF6_ENST00000374436 EIF6 P56537 Eukaryotic translation initiation factor 6 chr20 GO:1903706 Not Cancer Driver No 30 0.122 17 3 0.176 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:1903706 Census, Compendium Yes 275 0.219 314 41 0.131 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 GO:1903706 Compendium Yes 37 0.087 101 9 0.089 0
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:1903706 Not Cancer Driver No 68 0.154 78 9 0.115 0
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:1903706 Not Cancer Driver No 63 0.141 373 55 0.147 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:1903706 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:1903706 Not Cancer Driver No 10 0.052 32 0 0.0 0
FANCA FANCA O15360 Fanconi anemia group A protein chr16 GO:1903706 Census, Compendium Yes 160 0.11 154 15 0.097 27
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:1903706 Census, Compendium Yes 176 0.121 181 14 0.077 3
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:1903706 Not Cancer Driver No 39 0.117 9 0 0.0 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:1903706 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:1903706 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:1903706 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:1903706 Census Yes 51 0.165 99 30 0.303 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:1903706 Not Cancer Driver No 193 0.263 217 44 0.203 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:1903706 Census Yes 103 0.125 245 34 0.139 0
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:1903706 Not Cancer Driver No 71 0.162 70 12 0.171 0
FOS FOS P01100 Protein c-Fos chr14 GO:1903706 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:1903706 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:1903706 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:1903706 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:1903706 Census, Compendium Yes 109 0.161 448 71 0.158 3
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:1903706 Not Cancer Driver No 38 0.088 186 16 0.086 10
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:1903706 Not Cancer Driver No 31 0.24 0 0 0.0 1
FSTL3 FSTL3 O95633 Follistatin-related protein 3 chr19 GO:1903706 Census Yes 17 0.065 28 2 0.071 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:1903706 Not Cancer Driver No 58 0.128 103 8 0.078 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:1903706 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:1903706 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:1903706 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:1903706 Census, Compendium Yes 111 0.251 364 87 0.239 2
GFI1B GFI1B Q5VTD9 Zinc finger protein Gfi-1b chr9 GO:1903706 Not Cancer Driver No 50 0.152 142 23 0.162 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:1903706 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:1903706 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:1903706 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:1903706 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR171_ENST00000617554 GPR171 O14626 G-protein coupled receptor 171 chr3 GO:1903706 Not Cancer Driver No 50 0.157 8 2 0.25 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:1903706 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:1903706 Not Cancer Driver No 42 0.115 45 1 0.022 1
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:1903706 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:1903706 Not Cancer Driver No 103 0.212 446 94 0.211 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:1903706 Census Yes 118 0.143 435 51 0.117 0
HIST1H4A H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 15 0.146 31 5 0.161 0
HIST1H4B H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 29 0.282 31 6 0.194 0
HIST1H4C H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 29 0.282 31 7 0.226 0
HIST1H4D H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 32 0.311 31 8 0.258 0
HIST1H4E H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 45 0.437 31 14 0.452 0
HIST1H4F H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 30 0.291 31 7 0.226 0
HIST1H4H H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 22 0.214 31 9 0.29 0
HIST1H4I H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 33 0.32 31 10 0.323 0
HIST1H4J H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 26 0.252 31 9 0.29 0
HIST1H4K H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 44 0.427 31 13 0.419 0
HIST1H4L H4-16 P62805 Histone H4 chr6 GO:1903706 Not Cancer Driver No 25 0.243 31 14 0.452 0
HIST4H4 H4-16 P62805 Histone H4 chr12 GO:1903706 Not Cancer Driver No 21 0.204 31 7 0.226 0
HLA-B HLA-B P01889 HLA class I histocompatibility antigen, B alpha chain chr6 GO:1903706 Compendium Yes 78 0.215 169 34 0.201 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:1903706 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:1903706 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:1903706 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:1903706 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:1903706 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:1903706 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:1903706 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMGB3 HMGB3 O15347 High mobility group protein B3 chrX GO:1903706 Not Cancer Driver No 37 0.185 182 32 0.176 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:1903706 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:1903706 Not Cancer Driver No 60 0.261 71 15 0.211 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:1903706 Census Yes 46 0.169 187 35 0.187 0
HOXB8 HOXB8 P17481 Homeobox protein Hox-B8 chr17 GO:1903706 Not Cancer Driver No 35 0.144 121 15 0.124 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:1903706 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:1903706 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:1903706 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA9 HSPA9 P38646 Stress-70 protein, mitochondrial chr5 GO:1903706 Not Cancer Driver No 67 0.099 283 26 0.092 2
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:1903706 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:1903706 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:1903706 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:1903706 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:1903706 Not Cancer Driver No 24 0.12 49 8 0.163 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:1903706 Not Cancer Driver No 58 0.141 111 15 0.135 6
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 GO:1903706 Census, Compendium Yes 106 0.208 284 60 0.211 1
IL10 IL10 P22301 Interleukin-10 chr1 GO:1903706 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:1903706 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:1903706 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:1903706 Not Cancer Driver No 40 0.15 173 32 0.185 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:1903706 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:1903706 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL17D IL17D Q8TAD2 Interleukin-17D chr13 GO:1903706 Not Cancer Driver No 9 0.045 64 1 0.016 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:1903706 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:1903706 Census Yes 24 0.157 6 1 0.167 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:1903706 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:1903706 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:1903706 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL27 IL27 Q8NEV9 Interleukin-27 subunit alpha chr16 GO:1903706 Not Cancer Driver No 37 0.152 27 1 0.037 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:1903706 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:1903706 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:1903706 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:1903706 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:1903706 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL7 IL7 P13232 Interleukin-7 chr8 GO:1903706 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:1903706 Census, Compendium Yes 177 0.386 88 48 0.545 1
INHA INHA P05111 Inhibin alpha chain chr2 GO:1903706 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:1903706 Not Cancer Driver No 148 0.347 154 63 0.409 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:1903706 Not Cancer Driver No 176 0.148 578 90 0.156 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:1903706 Compendium Yes 49 0.151 228 31 0.136 2
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:1903706 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:1903706 Not Cancer Driver No 43 0.085 253 19 0.075 1
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:1903706 Not Cancer Driver No 12 0.073 24 2 0.083 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:1903706 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:1903706 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:1903706 Census, Compendium Yes 167 0.149 63 10 0.159 7
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:1903706 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:1903706 Census Yes 97 0.159 327 47 0.144 0
KITLG KITLG P21583 Kit ligand chr12 GO:1903706 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:1903706 Not Cancer Driver No 59 0.123 349 46 0.132 0
KLF13 KLF13 Q9Y2Y9 Krueppel-like factor 13 chr15 GO:1903706 Not Cancer Driver No 18 0.062 246 13 0.053 0
L3MBTL1 L3MBTL1 Q9Y468 Lethal(3)malignant brain tumor-like protein 1 chr20 GO:1903706 Not Cancer Driver No 116 0.138 447 40 0.089 0
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:1903706 Not Cancer Driver No 47 0.09 208 11 0.053 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:1903706 Compendium Yes 56 0.136 177 29 0.164 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:1903706 Census Yes 64 0.16 370 57 0.154 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:1903706 Not Cancer Driver No 74 0.111 611 69 0.113 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:1903706 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:1903706 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:1903706 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:1903706 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:1903706 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:1903706 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:1903706 Not Cancer Driver No 162 0.362 277 115 0.415 0
LOX LOX P28300 Protein-lysine 6-oxidase chr5 GO:1903706 Compendium Yes 44 0.106 172 11 0.064 4
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:1903706 Not Cancer Driver No 91 0.121 86 17 0.198 0
LRRC17 LRRC17 Q8N6Y2 Leucine-rich repeat-containing protein 17 chr7 GO:1903706 Not Cancer Driver No 58 0.132 88 11 0.125 0
LTF LTF P02788 Lactotransferrin chr3 GO:1903706 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:1903706 Census Yes 95 0.186 84 12 0.143 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:1903706 Census Yes 35 0.108 301 34 0.113 10
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:1903706 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:1903706 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:1903706 Not Cancer Driver No 39 0.108 25 1 0.04 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:1903706 Not Cancer Driver No 15 0.105 20 2 0.1 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:1903706 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:1903706 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:1903706 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:1903706 Not Cancer Driver No 94 0.197 358 76 0.212 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:1903706 Not Cancer Driver No 74 0.128 274 29 0.106 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:1903706 Census Yes 80 0.152 408 69 0.169 7
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:1903706 Not Cancer Driver No 64 0.11 118 11 0.093 1
MPL MPL P40238 Thrombopoietin receptor chr1 GO:1903706 Census Yes 77 0.121 129 19 0.147 14
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:1903706 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTURN MTURN Q8N3F0 Maturin chr7 GO:1903706 Not Cancer Driver No 15 0.115 27 6 0.222 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:1903706 Census Yes 82 0.128 528 69 0.131 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:1903706 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:1903706 Not Cancer Driver No 78 0.094 345 26 0.075 1
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:1903706 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:1903706 Not Cancer Driver No 22 0.1 44 4 0.091 0
NF1 NF1 P21359 Neurofibromin chr17 GO:1903706 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:1903706 Not Cancer Driver No 30 0.111 116 18 0.155 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:1903706 Compendium Yes 37 0.117 102 9 0.088 1
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:1903706 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:1903706 Not Cancer Driver No 96 0.134 443 53 0.12 0
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:1903706 Not Cancer Driver No 80 0.193 409 77 0.188 3
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:1903706 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:1903706 Census, Compendium Yes 282 0.114 630 77 0.122 1
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:1903706 Not Cancer Driver No 9 0.079 11 1 0.091 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:1903706 Not Cancer Driver No 22 0.039 52 6 0.115 0
P4HTM_ENST00000383729 P4HTM Q9NXG6 Transmembrane prolyl 4-hydroxylase chr3 GO:1903706 Not Cancer Driver No 76 0.151 144 20 0.139 1
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:1903706 Not Cancer Driver No 77 0.145 378 56 0.148 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:1903706 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:1903706 Not Cancer Driver No 142 0.228 110 28 0.255 1
PF4 PF4 P02776 Platelet factor 4 chr4 GO:1903706 Not Cancer Driver No 13 0.129 0 0 0.0 0
PGLYRP1 PGLYRP1 O75594 Peptidoglycan recognition protein 1 chr19 GO:1903706 Not Cancer Driver No 34 0.173 4 0 0.0 0
PGLYRP2 PGLYRP2 Q96PD5 N-acetylmuramoyl-L-alanine amidase chr19 GO:1903706 Not Cancer Driver No 111 0.193 160 28 0.175 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:1903706 Not Cancer Driver No 70 0.111 266 31 0.117 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:1903706 Census, Compendium Yes 154 0.213 268 61 0.228 2
PITHD1 PITHD1 Q9GZP4 PITH domain-containing protein 1 chr1 GO:1903706 Not Cancer Driver No 26 0.123 119 11 0.092 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:1903706 Not Cancer Driver No 115 0.226 175 39 0.223 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:1903706 Not Cancer Driver No 38 0.131 29 2 0.069 5
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:1903706 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:1903706 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:1903706 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:1903706 Not Cancer Driver No 44 0.097 30 3 0.1 0
PRDM1 PRDM1 O75626 PR domain zinc finger protein 1 chr6 GO:1903706 Census, Compendium Yes 145 0.176 337 66 0.196 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:1903706 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:1903706 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:1903706 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:1903706 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:1903706 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:1903706 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT6 PRMT6 Q96LA8 Protein arginine N-methyltransferase 6 chr1 GO:1903706 Not Cancer Driver No 43 0.115 71 7 0.099 0
PRXL2A PRXL2A Q9BRX8 Peroxiredoxin-like 2A chr10 GO:1903706 Not Cancer Driver No 34 0.148 0 0 0.0 0
PSG9 PSG9 Q00887 Pregnancy-specific beta-1-glycoprotein 9 chr19 GO:1903706 Not Cancer Driver No 125 0.293 40 8 0.2 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:1903706 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTN PTN P21246 Pleiotrophin chr7 GO:1903706 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:1903706 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:1903706 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:1903706 Census, Compendium Yes 315 0.241 462 107 0.232 0
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:1903706 Not Cancer Driver No 27 0.087 161 14 0.087 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:1903706 Not Cancer Driver No 118 0.224 85 23 0.271 6
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:1903706 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:1903706 Not Cancer Driver No 82 0.181 164 24 0.146 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:1903706 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:1903706 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:1903706 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBFOX2_ENST00000449924 RBFOX2 O43251 RNA binding protein fox-1 homolog 2 chr22 GO:1903706 Compendium Yes 44 0.113 173 22 0.127 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:1903706 Census, Compendium Yes 118 0.121 686 91 0.133 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:1903706 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:1903706 Not Cancer Driver No 128 0.107 703 81 0.115 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:1903706 Not Cancer Driver No 47 0.097 324 28 0.086 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:1903706 Not Cancer Driver No 35 0.203 116 27 0.233 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:1903706 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:1903706 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:1903706 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:1903706 Not Cancer Driver No 44 0.139 33 2 0.061 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:1903706 Not Cancer Driver No 203 0.215 299 71 0.237 5
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:1903706 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:1903706 Not Cancer Driver No 59 0.142 331 45 0.136 0
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:1903706 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:1903706 Not Cancer Driver No 59 0.155 327 49 0.15 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:1903706 Not Cancer Driver No 100 0.14 170 35 0.206 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:1903706 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3RF1 SH3RF1 Q7Z6J0 E3 ubiquitin-protein ligase SH3RF1 chr4 GO:1903706 Not Cancer Driver No 109 0.123 586 72 0.123 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:1903706 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:1903706 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:1903706 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:1903706 Not Cancer Driver No 68 0.127 80 16 0.2 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:1903706 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 GO:1903706 Not Cancer Driver No 54 0.116 352 46 0.131 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:1903706 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:1903706 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:1903706 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:1903706 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:1903706 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:1903706 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:1903706 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:1903706 Not Cancer Driver No 28 0.059 400 24 0.06 4
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:1903706 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:1903706 Not Cancer Driver No 168 0.158 590 102 0.173 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:1903706 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:1903706 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:1903706 Census, Compendium Yes 93 0.118 144 19 0.132 5
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:1903706 Census Yes 96 0.151 131 27 0.206 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:1903706 Census Yes 54 0.163 305 53 0.174 0
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:1903706 Not Cancer Driver No 70 0.131 348 50 0.144 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:1903706 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCTA TCTA P57738 T-cell leukemia translocation-altered gene protein chr3 GO:1903706 Not Cancer Driver No 13 0.126 34 3 0.088 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:1903706 Not Cancer Driver No 31 0.145 73 6 0.082 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:1903706 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFE3 TFE3 P19532 Transcription factor E3 chrX GO:1903706 Census Yes 92 0.16 524 84 0.16 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:1903706 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:1903706 Census, Compendium Yes 106 0.187 60 16 0.267 25
THPO THPO P40225 Thrombopoietin chr3 GO:1903706 Not Cancer Driver No 63 0.178 163 25 0.153 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:1903706 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:1903706 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:1903706 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:1903706 Not Cancer Driver No 188 0.117 448 47 0.105 0
TMEM176A_ENST00000004103 TMEM176A Q96HP8 Transmembrane protein 176A chr7 GO:1903706 Not Cancer Driver No 56 0.238 25 4 0.16 0
TMEM176B_ENST00000429904 TMEM176B Q3YBM2 Transmembrane protein 176B chr7 GO:1903706 Not Cancer Driver No 62 0.23 33 8 0.242 0
TMEM178A TMEM178A Q8NBL3 Transmembrane protein 178A chr2 GO:1903706 Not Cancer Driver No 52 0.175 40 2 0.05 0
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:1903706 Not Cancer Driver No 33 0.087 32 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:1903706 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:1903706 Not Cancer Driver No 62 0.224 13 5 0.385 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:1903706 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:1903706 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:1903706 Not Cancer Driver No 32 0.126 39 4 0.103 0
TOB2 TOB2 Q14106 Protein Tob2 chr22 GO:1903706 Not Cancer Driver No 36 0.105 147 16 0.109 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:1903706 Not Cancer Driver No 112 0.213 494 108 0.219 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:1903706 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:1903706 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:1903706 Not Cancer Driver No 47 0.126 91 5 0.055 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:1903706 Not Cancer Driver No 24 0.212 28 8 0.286 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 GO:1903706 Not Cancer Driver No 86 0.133 73 6 0.082 0
VNN1 VNN1 O95497 Pantetheinase chr6 GO:1903706 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:1903706 Not Cancer Driver No 52 0.167 135 19 0.141 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 GO:1903706 Not Cancer Driver No 25 0.082 7 1 0.143 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:1903706 Not Cancer Driver No 19 0.073 169 9 0.053 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:1903706 Not Cancer Driver No 66 0.108 140 12 0.086 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:1903706 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:1903706 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:1903706 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB46_ENST00000302995 ZBTB46 Q86UZ6 Zinc finger and BTB domain-containing protein 46 chr20 GO:1903706 Not Cancer Driver No 115 0.195 301 68 0.226 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:1903706 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:1903706 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:1903706 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:1903706 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:1903706 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:1903706 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:1903706 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZFPM1 ZFPM1 Q8IX07 Zinc finger protein ZFPM1 chr16 GO:1903706 Not Cancer Driver No 50 0.05 772 27 0.035 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:1903706 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:1903706 Not Cancer Driver No 114 0.201 91 19 0.209 0
ZNF683 ZNF683 Q8IZ20 Tissue-resident T-cell transcription regulator protein ZNF683 chr1 GO:1903706 Not Cancer Driver No 103 0.197 202 32 0.158 0