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Total number of protein in "GO:0071396" GO term:  242

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0071396 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCB4 ABCB4 P21439 Phosphatidylcholine translocator ABCB4 chr7 GO:0071396 Not Cancer Driver No 243 0.189 74 14 0.189 72
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0071396 Census, Compendium Yes 171 0.145 641 70 0.109 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0071396 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0071396 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0071396 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0071396 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0071396 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0071396 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0071396 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0071396 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0071396 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0071396 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADNP2 ADNP2 Q6IQ32 Activity-dependent neuroprotector homeobox protein 2 chr18 GO:0071396 Not Cancer Driver No 133 0.118 475 53 0.112 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0071396 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0071396 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0071396 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0071396 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0071396 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0071396 Not Cancer Driver No 78 0.241 9 3 0.333 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0071396 Not Cancer Driver No 100 0.193 56 13 0.232 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0071396 Not Cancer Driver No 59 0.171 61 12 0.197 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0071396 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0071396 Not Cancer Driver No 50 0.155 30 9 0.3 0
AR AR P10275 Androgen receptor chrX GO:0071396 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0071396 Not Cancer Driver No 41 0.127 83 12 0.145 9
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0071396 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0071396 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0071396 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0071396 Not Cancer Driver No 66 0.119 23 5 0.217 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0071396 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0071396 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0071396 Not Cancer Driver No 22 0.114 34 6 0.176 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0071396 Not Cancer Driver No 13 0.13 21 2 0.095 0
BHMG1 MEIOSIN C9JSJ3 Meiosis initiator protein chr19 GO:0071396 Not Cancer Driver No 0 0.0 498 0 0.0 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0071396 Not Cancer Driver No 273 0.359 36 17 0.472 0
BRINP2 BRINP2 Q9C0B6 BMP/retinoic acid-inducible neural-specific protein 2 chr1 GO:0071396 Not Cancer Driver No 271 0.346 13 2 0.154 0
BRINP3 BRINP3 Q76B58 BMP/retinoic acid-inducible neural-specific protein 3 chr1 GO:0071396 Not Cancer Driver No 439 0.573 15 10 0.667 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0071396 Census Yes 49 0.118 71 7 0.099 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0071396 Not Cancer Driver No 304 0.282 189 60 0.317 108
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0071396 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCDC62 CCDC62 Q6P9F0 Coiled-coil domain-containing protein 62 chr12 GO:0071396 Not Cancer Driver No 104 0.152 344 56 0.163 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0071396 Not Cancer Driver No 45 0.104 186 19 0.102 0
CDK4 CDK4 P11802 Cyclin-dependent kinase 4 chr12 GO:0071396 Census, Compendium Yes 52 0.172 52 5 0.096 3
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0071396 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0071396 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0071396 Not Cancer Driver No 287 0.194 145 18 0.124 151
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0071396 Not Cancer Driver No 31 0.147 16 3 0.188 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0071396 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0071396 Not Cancer Driver No 368 0.245 73 22 0.301 140
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0071396 Not Cancer Driver No 144 0.186 62 10 0.161 15
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0071396 Census Yes 25 0.076 277 23 0.083 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0071396 Not Cancer Driver No 61 0.189 0 0 0.0 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0071396 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0071396 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0071396 Not Cancer Driver No 109 0.216 48 8 0.167 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0071396 Not Cancer Driver No 102 0.114 485 61 0.126 4
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0071396 Not Cancer Driver No 20 0.086 87 9 0.103 0
DEFB104B DEFB104B Q8WTQ1 Beta-defensin 104 chr8 GO:0071396 Not Cancer Driver No 1 0.014 0 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0071396 Not Cancer Driver No 56 0.144 17 2 0.118 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0071396 Not Cancer Driver No 54 0.257 78 21 0.269 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0071396 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0071396 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0071396 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0071396 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0071396 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0071396 Not Cancer Driver No 51 0.119 327 34 0.104 0
EPHA3 EPHA3 P29320 Ephrin type-A receptor 3 chr3 GO:0071396 Census, Compendium Yes 346 0.352 74 28 0.378 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0071396 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0071396 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0071396 Not Cancer Driver No 90 0.17 92 11 0.12 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0071396 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0071396 Not Cancer Driver No 10 0.052 32 0 0.0 0
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0071396 Not Cancer Driver No 54 0.152 0 0 0.0 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0071396 Not Cancer Driver No 12 0.065 61 2 0.033 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0071396 Census Yes 103 0.125 245 34 0.139 0
FFAR2 FFAR2 O15552 Free fatty acid receptor 2 chr19 GO:0071396 Not Cancer Driver No 49 0.148 32 7 0.219 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0071396 Not Cancer Driver No 78 0.225 29 6 0.207 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0071396 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0071396 Census, Compendium Yes 238 0.29 228 44 0.193 72
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0071396 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0071396 Census, Compendium Yes 70 0.104 595 68 0.114 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0071396 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0071396 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0071396 Not Cancer Driver No 90 0.157 22 2 0.091 0
GDAP1 GDAP1 Q8TB36 Ganglioside-induced differentiation-associated protein 1 chr8 GO:0071396 Not Cancer Driver No 51 0.142 78 14 0.179 11
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0071396 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0071396 Not Cancer Driver No 48 0.178 13 0 0.0 6
GNAI1 GNAI1 P63096 Guanine nucleotide-binding protein G(i) subunit alpha-1 chr7 GO:0071396 Not Cancer Driver No 52 0.147 11 3 0.273 0
GPBAR1_ENST00000521462 GPBAR1 Q8TDU6 G-protein coupled bile acid receptor 1 chr2 GO:0071396 Not Cancer Driver No 30 0.091 22 4 0.182 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0071396 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0071396 Not Cancer Driver No 153 0.182 36 9 0.25 0
GRAMD1A GRAMD1A Q96CP6 Protein Aster-A chr19 GO:0071396 Not Cancer Driver No 83 0.115 261 33 0.126 0
GRAMD1B_ENST00000529750 GRAMD1B Q3KR37 Protein Aster-B chr11 GO:0071396 Not Cancer Driver No 140 0.19 335 69 0.206 0
GRAMD1C GRAMD1C Q8IYS0 Protein Aster-C chr3 GO:0071396 Not Cancer Driver No 103 0.156 205 31 0.151 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0071396 Not Cancer Driver No 56 0.133 146 13 0.089 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0071396 Not Cancer Driver No 23 0.18 71 16 0.225 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0071396 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0071396 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0071396 Not Cancer Driver No 46 0.094 145 14 0.097 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0071396 Not Cancer Driver No 37 0.132 226 32 0.142 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0071396 Not Cancer Driver No 92 0.181 29 4 0.138 19
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0071396 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0071396 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 GO:0071396 Not Cancer Driver No 58 0.154 281 48 0.171 1
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0071396 Not Cancer Driver No 59 0.112 335 37 0.11 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0071396 Compendium Yes 44 0.096 127 9 0.071 2
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0071396 Census, Compendium Yes 14 0.118 34 4 0.118 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0071396 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0071396 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0071396 Not Cancer Driver No 25 0.154 6 1 0.167 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0071396 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0071396 Not Cancer Driver No 61 0.15 98 5 0.051 0
INSIG1 INSIG1 O15503 Insulin-induced gene 1 protein chr7 GO:0071396 Not Cancer Driver No 37 0.134 43 1 0.023 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0071396 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0071396 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0071396 Not Cancer Driver No 166 0.141 26 0 0.0 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0071396 Census, Compendium Yes 136 0.12 59 5 0.085 5
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0071396 Not Cancer Driver No 65 0.127 173 21 0.121 3
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0071396 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0071396 Not Cancer Driver No 49 0.257 0 0 0.0 0
KIF18A KIF18A Q8NI77 Kinesin-like protein KIF18A chr11 GO:0071396 Not Cancer Driver No 114 0.127 405 60 0.148 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0071396 Not Cancer Driver No 34 0.139 154 24 0.156 0
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0071396 Not Cancer Driver No 54 0.125 388 46 0.119 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0071396 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEP LEP P41159 Leptin chr7 GO:0071396 Not Cancer Driver No 29 0.174 0 0 0.0 2
LPL LPL P06858 Lipoprotein lipase chr8 GO:0071396 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0071396 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0071396 Not Cancer Driver No 94 0.098 190 24 0.126 0
LTK LTK P29376 Leukocyte tyrosine kinase receptor chr15 GO:0071396 Not Cancer Driver No 103 0.119 301 30 0.1 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0071396 Census Yes 95 0.186 84 12 0.143 0
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0071396 Not Cancer Driver No 116 0.139 276 41 0.149 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0071396 Not Cancer Driver No 54 0.205 47 13 0.277 0
MGST1_ENST00000396210 MGST1 P10620 Microsomal glutathione S-transferase 1 chr12 GO:0071396 Not Cancer Driver No 26 0.168 0 0 0.0 0
MLC1 MLC1 Q15049 Membrane protein MLC1 chr22 GO:0071396 Not Cancer Driver No 53 0.141 35 7 0.2 15
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0071396 Not Cancer Driver No 123 0.186 29 6 0.207 2
MSN MSN P26038 Moesin chrX GO:0071396 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0071396 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0071396 Not Cancer Driver No 27 0.101 168 14 0.083 4
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0071396 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0071396 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0071396 Not Cancer Driver No 36 0.161 132 20 0.152 0
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0071396 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDUFA13 NDUFA13 Q9P0J0 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 chr19 GO:0071396 Not Cancer Driver No 29 0.201 24 4 0.167 1
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0071396 Not Cancer Driver No 229 0.286 429 114 0.266 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0071396 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0071396 Not Cancer Driver No 92 0.118 362 37 0.102 12
NRIP1_ENST00000400199 NRIP1 P48552 Nuclear receptor-interacting protein 1 chr21 GO:0071396 Not Cancer Driver No 141 0.122 998 124 0.124 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0071396 Census, Compendium Yes 249 0.297 57 21 0.368 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0071396 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBPL7_ENST00000392507 OSBPL7 Q9BZF2 Oxysterol-binding protein-related protein 7 chr17 GO:0071396 Not Cancer Driver No 99 0.118 395 44 0.111 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0071396 Not Cancer Driver No 57 0.214 67 17 0.254 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0071396 Not Cancer Driver No 62 0.149 296 48 0.162 23
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0071396 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0071396 Not Cancer Driver No 91 0.142 139 13 0.094 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0071396 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0071396 Not Cancer Driver No 70 0.17 14 2 0.143 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0071396 Not Cancer Driver No 109 0.408 142 62 0.437 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0071396 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0071396 Not Cancer Driver No 144 0.192 56 7 0.125 30
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0071396 Not Cancer Driver No 70 0.28 24 10 0.417 0
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0071396 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0071396 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0071396 Not Cancer Driver No 248 0.196 142 30 0.211 1
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0071396 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0071396 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0071396 Not Cancer Driver No 47 0.058 695 35 0.05 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0071396 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0071396 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0071396 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0071396 Census Yes 42 0.093 12 0 0.0 0
PTK7_ENST00000230419 PTK7 Q13308 Inactive tyrosine-protein kinase 7 chr6 GO:0071396 Not Cancer Driver No 153 0.143 359 58 0.162 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0071396 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0071396 Not Cancer Driver No 20 0.093 14 1 0.071 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0071396 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARG RARG P13631 Retinoic acid receptor gamma chr12 GO:0071396 Not Cancer Driver No 82 0.181 164 24 0.146 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0071396 Not Cancer Driver No 142 0.129 868 113 0.13 4
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0071396 Census, Compendium Yes 208 0.187 105 12 0.114 139
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0071396 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0071396 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0071396 Not Cancer Driver No 107 0.228 87 22 0.253 1
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0071396 Not Cancer Driver No 96 0.185 187 36 0.193 1
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0071396 Not Cancer Driver No 45 0.086 226 26 0.115 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0071396 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD1 RWDD1 Q9H446 RWD domain-containing protein 1 chr6 GO:0071396 Not Cancer Driver No 28 0.115 168 19 0.113 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0071396 Not Cancer Driver No 51 0.122 57 5 0.088 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0071396 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0071396 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0071396 Census, Compendium Yes 58 0.135 86 16 0.186 0
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0071396 Not Cancer Driver No 101 0.16 73 12 0.164 0
SMARCD1 SMARCD1 Q96GM5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 chr12 GO:0071396 Census, Compendium Yes 48 0.093 216 18 0.083 2
SMO SMO Q99835 Smoothened homolog chr7 GO:0071396 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0071396 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0071396 Not Cancer Driver No 62 0.116 488 56 0.115 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0071396 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0071396 Compendium Yes 86 0.169 495 82 0.166 18
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0071396 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0071396 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0071396 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0071396 Not Cancer Driver No 35 0.135 0 0 0.0 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0071396 Not Cancer Driver No 127 0.111 528 64 0.121 4
SSTR1 SSTR1 P30872 Somatostatin receptor type 1 chr14 GO:0071396 Not Cancer Driver No 96 0.246 50 12 0.24 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0071396 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0071396 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0071396 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0071396 Not Cancer Driver No 60 0.165 45 12 0.267 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0071396 Not Cancer Driver No 59 0.239 58 12 0.207 0
STRA8 STRA8 Q7Z7C7 Stimulated by retinoic acid gene 8 protein homolog chr7 GO:0071396 Not Cancer Driver No 45 0.136 105 15 0.143 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0071396 Census Yes 96 0.151 131 27 0.206 5
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0071396 Not Cancer Driver No 35 0.088 197 12 0.061 4
TEAD2_ENST00000311227 TEAD2 Q15562 Transcriptional enhancer factor TEF-4 chr19 GO:0071396 Not Cancer Driver No 66 0.148 220 31 0.141 0
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0071396 Not Cancer Driver No 31 0.145 73 6 0.082 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0071396 Compendium Yes 61 0.18 285 52 0.182 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0071396 Not Cancer Driver No 24 0.103 45 3 0.067 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0071396 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0071396 Not Cancer Driver No 226 0.188 957 167 0.175 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0071396 Not Cancer Driver No 34 0.097 59 8 0.136 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0071396 Not Cancer Driver No 19 0.123 32 4 0.125 0
UCP1 UCP1 P25874 Mitochondrial brown fat uncoupling protein 1 chr4 GO:0071396 Not Cancer Driver No 43 0.14 1 0 0.0 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0071396 Not Cancer Driver No 100 0.188 11 2 0.182 55
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0071396 Census, Compendium Yes 122 0.109 602 69 0.115 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0071396 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0071396 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0071396 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0071396 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0071396 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0071396 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0071396 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0071396 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0071396 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0071396 Not Cancer Driver No 50 0.142 27 5 0.185 0
WNT9A WNT9A O14904 Protein Wnt-9a chr1 GO:0071396 Not Cancer Driver No 74 0.203 44 11 0.25 0
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0071396 Not Cancer Driver No 47 0.132 11 4 0.364 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0071396 Not Cancer Driver No 87 0.119 118 11 0.093 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0071396 Not Cancer Driver No 51 0.101 489 49 0.1 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0071396 Not Cancer Driver No 65 0.12 62 10 0.161 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0071396 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0071396 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0071396 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0071396 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF35 ZNF35 P13682 Zinc finger protein 35 chr3 GO:0071396 Not Cancer Driver No 66 0.125 192 17 0.089 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0071396 Not Cancer Driver No 26 0.044 415 14 0.034 0