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Total number of protein in "GO:0060429" GO term:  112

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0060429 Not Cancer Driver No 45 0.105 32 1 0.031 10
ADAMTSL2_ENST00000393060 ADAMTSL2 Q86TH1 ADAMTS-like protein 2 chr9 GO:0060429 Not Cancer Driver No 42 0.044 234 5 0.021 14
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0060429 Not Cancer Driver No 120 0.1 500 56 0.112 6
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0060429 Not Cancer Driver No 126 0.115 316 31 0.098 1
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0060429 Not Cancer Driver No 23 0.085 0 0 0.0 0
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0060429 Not Cancer Driver No 25 0.071 58 3 0.052 0
ATP2C2_ENST00000262429 ATP2C2 O75185 Calcium-transporting ATPase type 2C member 2 chr16 GO:0060429 Not Cancer Driver No 123 0.13 54 6 0.111 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0060429 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0060429 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0060429 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPER BMPER Q8N8U9 BMP-binding endothelial regulator protein chr7 GO:0060429 Not Cancer Driver No 196 0.286 0 0 0.0 1
C3 C3 P01024 Complement C3 chr19 GO:0060429 Not Cancer Driver No 337 0.203 287 50 0.174 12
CALB1 CALB1 P05937 Calbindin chr8 GO:0060429 Not Cancer Driver No 46 0.176 0 0 0.0 0
CAT CAT P04040 Catalase chr11 GO:0060429 Not Cancer Driver No 70 0.133 176 18 0.102 0
CCM2_ENST00000258781 CCM2 Q9BSQ5 Cerebral cavernous malformations 2 protein chr7 GO:0060429 Not Cancer Driver No 58 0.131 132 8 0.061 3
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0060429 Not Cancer Driver No 65 0.169 221 34 0.154 0
CER1 CER1 O95813 Cerberus chr9 GO:0060429 Not Cancer Driver No 70 0.262 119 27 0.227 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0060429 Not Cancer Driver No 464 0.155 1872 299 0.16 50
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0060429 Census Yes 258 0.174 1215 207 0.17 64
CRLF1 CRLF1 O75462 Cytokine receptor-like factor 1 chr19 GO:0060429 Not Cancer Driver No 51 0.121 101 7 0.069 14
CSMD1 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0060429 Not Cancer Driver No 1236 0.347 234 76 0.325 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0060429 Census, Compendium Yes 415 0.531 288 301 1.045 14
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0060429 Not Cancer Driver No 115 0.159 145 24 0.166 1
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0060429 Not Cancer Driver No 62 0.145 21 6 0.286 2
EPCAM EPCAM P16422 Epithelial cell adhesion molecule chr2 GO:0060429 Not Cancer Driver No 40 0.127 25 2 0.08 1
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0060429 Not Cancer Driver No 55 0.119 297 37 0.125 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0060429 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0060429 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0060429 Census, Compendium Yes 238 0.29 228 44 0.193 72
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0060429 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0060429 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0060429 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0060429 Not Cancer Driver No 25 0.059 279 18 0.065 0
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0060429 Not Cancer Driver No 58 0.178 31 6 0.194 1
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0060429 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0060429 Not Cancer Driver No 57 0.096 476 51 0.107 10
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0060429 Not Cancer Driver No 40 0.098 109 7 0.064 1
GJA4 GJA4 P35212 Gap junction alpha-4 protein chr1 GO:0060429 Not Cancer Driver No 48 0.144 74 14 0.189 0
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0060429 Not Cancer Driver No 74 0.207 92 21 0.228 5
GREB1L GREB1L Q9C091 GREB1-like protein chr18 GO:0060429 Not Cancer Driver No 87 0.045 480 22 0.046 25
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0060429 Not Cancer Driver No 173 0.125 974 135 0.139 0
HEYL HEYL Q9NQ87 Hairy/enhancer-of-split related with YRPW motif-like protein chr1 GO:0060429 Not Cancer Driver No 44 0.134 198 19 0.096 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0060429 Not Cancer Driver No 58 0.141 111 15 0.135 6
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0060429 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0060429 Census, Compendium Yes 136 0.12 59 5 0.085 5
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 GO:0060429 Not Cancer Driver No 107 0.126 531 71 0.134 3
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0060429 Not Cancer Driver No 61 0.153 277 50 0.181 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0060429 Census, Compendium Yes 357 0.263 275 55 0.2 2
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0060429 Not Cancer Driver No 91 0.121 86 17 0.198 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0060429 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEOX1 MEOX1 P50221 Homeobox protein MOX-1 chr17 GO:0060429 Not Cancer Driver No 46 0.181 236 44 0.186 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 GO:0060429 Not Cancer Driver No 70 0.23 274 63 0.23 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0060429 Not Cancer Driver No 61 0.112 36 4 0.111 7
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0060429 Not Cancer Driver No 39 0.129 197 16 0.081 7
MTHFD1 MTHFD1 P11586 C-1-tetrahydrofolate synthase, cytoplasmic chr14 GO:0060429 Not Cancer Driver No 103 0.11 129 11 0.085 6
NKX2-6 NKX2-6 A6NCS4 Homeobox protein Nkx-2.6 chr8 GO:0060429 Not Cancer Driver No 10 0.033 243 7 0.029 3
NOG NOG Q13253 Noggin chr17 GO:0060429 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0060429 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0060429 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0060429 Not Cancer Driver No 90 0.159 218 33 0.151 0
NUP133 NUP133 Q8WUM0 Nuclear pore complex protein Nup133 chr1 GO:0060429 Not Cancer Driver No 143 0.124 116 16 0.138 3
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0060429 Not Cancer Driver No 26 0.086 101 9 0.089 5
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0060429 Not Cancer Driver No 57 0.214 67 17 0.254 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0060429 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0060429 Census Yes 84 0.187 291 55 0.189 4
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0060429 Not Cancer Driver No 2 0.003 153 2 0.013 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0060429 Not Cancer Driver No 58 0.114 142 23 0.162 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0060429 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0060429 Not Cancer Driver No 113 0.117 375 35 0.093 10
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0060429 Not Cancer Driver No 43 0.086 402 30 0.075 4
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0060429 Census, Compendium Yes 243 0.168 382 67 0.175 18
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0060429 Census Yes 45 0.117 13 0 0.0 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0060429 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0060429 Not Cancer Driver No 229 0.128 1626 212 0.13 0
RCN3 RCN3 Q96D15 Reticulocalbin-3 chr19 GO:0060429 Not Cancer Driver No 44 0.134 243 39 0.16 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0060429 Census, Compendium Yes 208 0.187 105 12 0.114 139
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0060429 Census Yes 407 0.295 874 259 0.296 2
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 GO:0060429 Not Cancer Driver No 177 0.135 586 94 0.16 8
SALL1 SALL1 Q9NSC2 Sal-like protein 1 chr16 GO:0060429 Not Cancer Driver No 454 0.343 949 334 0.352 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0060429 Not Cancer Driver No 31 0.1 259 30 0.116 0
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0060429 Census, Compendium Yes 34 0.172 110 25 0.227 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0060429 Not Cancer Driver No 62 0.156 0 0 0.0 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0060429 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0060429 Not Cancer Driver No 40 0.127 39 7 0.179 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0060429 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIM1_ENST00000262901 SIM1 P81133 Single-minded homolog 1 chr6 GO:0060429 Not Cancer Driver No 223 0.291 376 120 0.319 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0060429 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0060429 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0060429 Not Cancer Driver No 428 0.28 31 13 0.419 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0060429 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0060429 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0060429 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0060429 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0060429 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0060429 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0060429 Census, Compendium Yes 112 0.142 241 27 0.112 1
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0060429 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0060429 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0060429 Compendium Yes 86 0.169 495 82 0.166 18
SPRY1 SPRY1 O43609 Protein sprouty homolog 1 chr4 GO:0060429 Not Cancer Driver No 46 0.144 168 26 0.155 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0060429 Not Cancer Driver No 131 0.175 144 25 0.174 26
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0060429 Not Cancer Driver No 77 0.115 84 14 0.167 6
TBC1D32 TBC1D32 Q96NH3 Protein broad-minded chr6 GO:0060429 Not Cancer Driver No 173 0.138 110 19 0.173 0
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0060429 Not Cancer Driver No 155 0.299 351 113 0.322 5
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0060429 Not Cancer Driver No 55 0.307 120 40 0.333 0
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0060429 Not Cancer Driver No 114 0.248 306 75 0.245 6
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0060429 Not Cancer Driver No 74 0.137 98 12 0.122 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0060429 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT2 WNT2 P09544 Protein Wnt-2 chr7 GO:0060429 Not Cancer Driver No 85 0.236 11 3 0.273 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0060429 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0060429 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0060429 Not Cancer Driver No 55 0.158 11 1 0.091 0