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Total number of protein in "GO:0051607" GO term:  229

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC9_ENST00000261201 ABCC9 O60706 ATP-binding cassette sub-family C member 9 chr12 GO:0051607 Not Cancer Driver No 368 0.238 132 30 0.227 15
ABCF3 ABCF3 Q9NUQ8 ATP-binding cassette sub-family F member 3 chr3 GO:0051607 Not Cancer Driver No 109 0.154 136 19 0.14 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0051607 Not Cancer Driver No 5 0.01 36 0 0.0 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0051607 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0051607 Not Cancer Driver No 102 0.138 348 34 0.098 1
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 GO:0051607 Not Cancer Driver No 65 0.129 72 2 0.028 0
AGBL5 AGBL5 Q8NDL9 Cytosolic carboxypeptidase-like protein 5 chr2 GO:0051607 Not Cancer Driver No 127 0.143 487 74 0.152 2
AICDA AICDA Q9GZX7 Single-stranded DNA cytosine deaminase chr12 GO:0051607 Not Cancer Driver No 56 0.283 0 0 0.0 8
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 GO:0051607 Not Cancer Driver No 107 0.118 537 67 0.125 0
APOBEC3A_ENST00000249116 APOBEC3A P31941 DNA dC->dU-editing enzyme APOBEC-3A chr22 GO:0051607 Not Cancer Driver No 27 0.136 8 1 0.125 0
APOBEC3B APOBEC3B Q9UH17 DNA dC->dU-editing enzyme APOBEC-3B chr22 GO:0051607 Census Yes 61 0.16 1 0 0.0 0
APOBEC3C APOBEC3C Q9NRW3 DNA dC->dU-editing enzyme APOBEC-3C chr22 GO:0051607 Not Cancer Driver No 28 0.147 2 0 0.0 0
APOBEC3D APOBEC3D Q96AK3 DNA dC->dU-editing enzyme APOBEC-3D chr22 GO:0051607 Not Cancer Driver No 43 0.111 3 0 0.0 0
APOBEC3F APOBEC3F Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F chr22 GO:0051607 Not Cancer Driver No 49 0.131 0 0 0.0 0
APOBEC3G APOBEC3G Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G chr22 GO:0051607 Not Cancer Driver No 61 0.159 0 0 0.0 0
APOBEC3H_ENST00000613677 APOBEC3H Q6NTF7 DNA dC->dU-editing enzyme APOBEC-3H chr22 GO:0051607 Not Cancer Driver No 39 0.195 0 0 0.0 0
ARMC5_ENST00000563544 ARMC5 Q96C12 Armadillo repeat-containing protein 5 chr16 GO:0051607 Not Cancer Driver No 135 0.144 267 41 0.154 17
ATAD3A ATAD3A Q9NVI7 ATPase family AAA domain-containing protein 3A chr1 GO:0051607 Not Cancer Driver No 66 0.104 269 24 0.089 2
ATG16L1 ATG16L1 Q676U5 Autophagy-related protein 16-1 chr2 GO:0051607 Not Cancer Driver No 79 0.13 239 25 0.105 1
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0051607 Compendium Yes 77 0.11 53 8 0.151 6
AZU1 AZU1 P20160 Azurocidin chr19 GO:0051607 Not Cancer Driver No 42 0.167 53 13 0.245 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0051607 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0051607 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0051607 Not Cancer Driver No 45 0.1 190 19 0.1 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0051607 Not Cancer Driver No 16 0.073 175 14 0.08 0
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 GO:0051607 Not Cancer Driver No 54 0.211 0 0 0.0 0
BST2 BST2 Q10589 Bone marrow stromal antigen 2 chr19 GO:0051607 Not Cancer Driver No 19 0.106 20 0 0.0 0
C19orf66 SHFL Q9NUL5 Shiftless antiviral inhibitor of ribosomal frameshifting protein chr19 GO:0051607 Not Cancer Driver No 23 0.079 166 12 0.072 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0051607 Not Cancer Driver No 53 0.099 126 7 0.056 1
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0051607 Not Cancer Driver No 72 0.134 225 35 0.156 11
CD207 CD207 Q9UJ71 C-type lectin domain family 4 member K chr2 GO:0051607 Not Cancer Driver No 77 0.235 56 13 0.232 1
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0051607 Not Cancer Driver No 39 0.141 56 6 0.107 2
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0051607 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0051607 Not Cancer Driver No 25 0.113 137 13 0.095 0
CLPB CLPB Q9H078 Caseinolytic peptidase B protein homolog chr11 GO:0051607 Not Cancer Driver No 69 0.098 224 25 0.112 11
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0051607 Not Cancer Driver No 31 0.109 21 1 0.048 0
CRCP CRCP O75575 DNA-directed RNA polymerase III subunit RPC9 chr7 GO:0051607 Not Cancer Driver No 11 0.074 113 4 0.035 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0051607 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0051607 Not Cancer Driver No 32 0.256 38 16 0.421 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0051607 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0051607 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX17_ENST00000640332 DDX17 Q92841 Probable ATP-dependent RNA helicase DDX17 chr22 GO:0051607 Not Cancer Driver No 91 0.125 362 48 0.133 0
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0051607 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0051607 Not Cancer Driver No 118 0.128 61 10 0.164 2
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0051607 Not Cancer Driver No 224 0.131 131 12 0.092 0
DDX60L DDX60L Q5H9U9 Probable ATP-dependent RNA helicase DDX60-like chr4 GO:0051607 Not Cancer Driver No 219 0.128 84 10 0.119 0
DEFA3 DEFA3 P59666 Neutrophil defensin 3 chr8 GO:0051607 Not Cancer Driver No 15 0.16 0 0 0.0 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0051607 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0051607 Not Cancer Driver No 62 0.091 84 8 0.095 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0051607 Not Cancer Driver No 506 0.21 404 64 0.158 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0051607 Not Cancer Driver No 60 0.119 131 17 0.13 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0051607 Not Cancer Driver No 86 0.116 260 24 0.092 0
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0051607 Not Cancer Driver No 59 0.107 188 22 0.117 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0051607 Not Cancer Driver No 156 0.095 494 44 0.089 2
ELMOD2 ELMOD2 Q8IZ81 ELMO domain-containing protein 2 chr4 GO:0051607 Not Cancer Driver No 29 0.099 0 0 0.0 0
EXOC1 EXOC1 Q9NV70 Exocyst complex component 1 chr4 GO:0051607 Not Cancer Driver No 128 0.143 154 22 0.143 0
EXOSC4 EXOSC4 Q9NPD3 Exosome complex component RRP41 chr8 GO:0051607 Not Cancer Driver No 34 0.139 23 0 0.0 0
EXOSC5 EXOSC5 Q9NQT4 Exosome complex component RRP46 chr19 GO:0051607 Not Cancer Driver No 43 0.183 31 3 0.097 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0051607 Not Cancer Driver No 55 0.139 7 2 0.286 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0051607 Not Cancer Driver No 26 0.125 45 10 0.222 1
FCN3 FCN3 O75636 Ficolin-3 chr1 GO:0051607 Not Cancer Driver No 46 0.154 65 19 0.292 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0051607 Not Cancer Driver No 85 0.182 352 65 0.185 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0051607 Not Cancer Driver No 92 0.155 166 27 0.163 0
GBP3 GBP3 Q9H0R5 Guanylate-binding protein 3 chr1 GO:0051607 Not Cancer Driver No 76 0.128 128 15 0.117 0
GBP7 GBP7 Q8N8V2 Guanylate-binding protein 7 chr1 GO:0051607 Not Cancer Driver No 88 0.138 93 8 0.086 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0051607 Not Cancer Driver No 108 0.13 83 7 0.084 0
HERC5 HERC5 Q9UII4 E3 ISG15--protein ligase HERC5 chr4 GO:0051607 Not Cancer Driver No 124 0.121 118 12 0.102 0
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0051607 Not Cancer Driver No 52 0.11 8 1 0.125 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0051607 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFI27_ENST00000621160 IFI27 P40305 Interferon alpha-inducible protein 27, mitochondrial chr14 GO:0051607 Not Cancer Driver No 10 0.082 0 0 0.0 0
IFI44L IFI44L Q53G44 Interferon-induced protein 44-like chr1 GO:0051607 Not Cancer Driver No 102 0.226 7 2 0.286 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0051607 Not Cancer Driver No 12 0.092 7 0 0.0 0
IFIH1 IFIH1 Q9BYX4 Interferon-induced helicase C domain-containing protein 1 chr2 GO:0051607 Not Cancer Driver No 109 0.106 287 36 0.125 9
IFIT1 IFIT1 P09914 Interferon-induced protein with tetratricopeptide repeats 1 chr10 GO:0051607 Not Cancer Driver No 49 0.103 52 3 0.058 0
IFIT1B IFIT1B Q5T764 Interferon-induced protein with tetratricopeptide repeats 1B chr10 GO:0051607 Not Cancer Driver No 59 0.124 21 1 0.048 0
IFIT2_ENST00000371826 IFIT2 P09913 Interferon-induced protein with tetratricopeptide repeats 2 chr10 GO:0051607 Not Cancer Driver No 73 0.155 85 17 0.2 0
IFIT3_ENST00000371811 IFIT3 O14879 Interferon-induced protein with tetratricopeptide repeats 3 chr10 GO:0051607 Not Cancer Driver No 47 0.096 143 11 0.077 0
IFIT5 IFIT5 Q13325 Interferon-induced protein with tetratricopeptide repeats 5 chr10 GO:0051607 Not Cancer Driver No 43 0.089 19 0 0.0 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 GO:0051607 Not Cancer Driver No 19 0.152 0 0 0.0 0
IFITM2_ENST00000399817 IFITM2 Q01629 Interferon-induced transmembrane protein 2 chr11 GO:0051607 Not Cancer Driver No 23 0.174 17 5 0.294 0
IFITM3 IFITM3 Q01628 Interferon-induced transmembrane protein 3 chr11 GO:0051607 Not Cancer Driver No 69 0.519 18 5 0.278 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0051607 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0051607 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0051607 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0051607 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0051607 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0051607 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0051607 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0051607 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0051607 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0051607 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0051607 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0051607 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNAR2 IFNAR2 P48551 Interferon alpha/beta receptor 2 chr21 GO:0051607 Not Cancer Driver No 58 0.113 199 24 0.121 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0051607 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0051607 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0051607 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0051607 Compendium Yes 55 0.112 175 22 0.126 10
IFNGR2_ENST00000290219 IFNGR2 P38484 Interferon gamma receptor 2 chr21 GO:0051607 Not Cancer Driver No 36 0.107 18 2 0.111 5
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0051607 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0051607 Not Cancer Driver No 24 0.12 49 8 0.163 0
IFNL2 IFNL2 Q8IZJ0 Interferon lambda-2 chr19 GO:0051607 Not Cancer Driver No 38 0.19 5 0 0.0 0
IFNL3 IFNL3 Q8IZI9 Interferon lambda-3 chr19 GO:0051607 Not Cancer Driver No 46 0.235 26 5 0.192 0
IFNLR1 IFNLR1 Q8IU57 Interferon lambda receptor 1 chr1 GO:0051607 Not Cancer Driver No 57 0.11 256 33 0.129 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0051607 Not Cancer Driver No 32 0.164 10 3 0.3 0
IL10RB IL10RB Q08334 Interleukin-10 receptor subunit beta chr21 GO:0051607 Not Cancer Driver No 52 0.16 39 5 0.128 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051607 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL21 IL21 Q9HBE4 Interleukin-21 chr4 GO:0051607 Not Cancer Driver No 34 0.21 70 18 0.257 1
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0051607 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0051607 Not Cancer Driver No 35 0.165 58 7 0.121 0
ILF3_ENST00000590261 ILF3 Q12906 Interleukin enhancer-binding factor 3 chr19 GO:0051607 Not Cancer Driver No 103 0.115 674 82 0.122 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0051607 Compendium Yes 49 0.151 228 31 0.136 2
IRF2 IRF2 P14316 Interferon regulatory factor 2 chr4 GO:0051607 Not Cancer Driver No 85 0.244 288 73 0.253 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0051607 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 GO:0051607 Not Cancer Driver No 93 0.187 237 64 0.27 0
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0051607 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRF9 IRF9 Q00978 Interferon regulatory factor 9 chr14 GO:0051607 Not Cancer Driver No 48 0.122 204 15 0.074 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0051607 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISG20 ISG20 Q96AZ6 Interferon-stimulated gene 20 kDa protein chr15 GO:0051607 Not Cancer Driver No 20 0.11 6 0 0.0 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0051607 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGAX_ENST00000268296 ITGAX P20702 Integrin alpha-X chr16 GO:0051607 Not Cancer Driver No 245 0.211 82 15 0.183 0
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0051607 Not Cancer Driver No 99 0.233 68 22 0.324 1
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0051607 Not Cancer Driver No 203 0.312 291 97 0.333 0
LYST LYST Q99698 Lysosomal-trafficking regulator chr1 GO:0051607 Not Cancer Driver No 465 0.122 608 87 0.143 4
MAP3K14 MAP3K14 Q99558 Mitogen-activated protein kinase kinase kinase 14 chr17 GO:0051607 Not Cancer Driver No 94 0.099 543 52 0.096 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0051607 Not Cancer Driver No 33 0.134 23 5 0.217 0
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0051607 Not Cancer Driver No 70 0.13 411 58 0.141 0
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX GO:0051607 Not Cancer Driver No 112 0.152 95 24 0.253 1
MLKL MLKL Q8NB16 Mixed lineage kinase domain-like protein chr16 GO:0051607 Not Cancer Driver No 56 0.119 89 15 0.169 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0051607 Not Cancer Driver No 110 0.11 101 8 0.079 0
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 GO:0051607 Not Cancer Driver No 88 0.133 74 10 0.135 0
MX2 MX2 P20592 Interferon-induced GTP-binding protein Mx2 chr21 GO:0051607 Not Cancer Driver No 96 0.134 159 25 0.157 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0051607 Census, Compendium Yes 37 0.125 47 1 0.021 2
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0051607 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCBP3 NCBP3 Q53F19 Nuclear cap-binding protein subunit 3 chr17 GO:0051607 Not Cancer Driver No 52 0.084 507 42 0.083 0
NDUFAF4 NDUFAF4 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 chr6 GO:0051607 Not Cancer Driver No 14 0.08 46 4 0.087 2
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0051607 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0051607 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP9 NLRP9 Q7RTR0 NACHT, LRR and PYD domains-containing protein 9 chr19 GO:0051607 Not Cancer Driver No 247 0.249 0 0 0.0 0
NT5C3A NT5C3A Q9H0P0 Cytosolic 5'-nucleotidase 3A chr7 GO:0051607 Compendium Yes 44 0.131 0 0 0.0 8
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0051607 Not Cancer Driver No 67 0.168 71 12 0.169 0
OAS2 OAS2 P29728 2'-5'-oligoadenylate synthase 2 chr12 GO:0051607 Not Cancer Driver No 141 0.196 47 14 0.298 0
OAS3 OAS3 Q9Y6K5 2'-5'-oligoadenylate synthase 3 chr12 GO:0051607 Not Cancer Driver No 139 0.128 147 17 0.116 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0051607 Not Cancer Driver No 76 0.148 8 4 0.5 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0051607 Not Cancer Driver No 117 0.308 18 5 0.278 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0051607 Not Cancer Driver No 110 0.129 45 3 0.067 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 GO:0051607 Not Cancer Driver No 40 0.11 200 24 0.12 0
PDE12 PDE12 Q6L8Q7 2',5'-phosphodiesterase 12 chr3 GO:0051607 Not Cancer Driver No 59 0.097 129 8 0.062 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0051607 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0051607 Not Cancer Driver No 37 0.136 4 1 0.25 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0051607 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0051607 Not Cancer Driver No 43 0.135 92 13 0.141 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0051607 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0051607 Census, Compendium Yes 112 0.127 312 34 0.109 0
POLR3A POLR3A O14802 DNA-directed RNA polymerase III subunit RPC1 chr10 GO:0051607 Not Cancer Driver No 155 0.112 113 17 0.15 15
POLR3B POLR3B Q9NW08 DNA-directed RNA polymerase III subunit RPC2 chr12 GO:0051607 Not Cancer Driver No 164 0.145 117 20 0.171 8
POLR3C POLR3C Q9BUI4 DNA-directed RNA polymerase III subunit RPC3 chr1 GO:0051607 Not Cancer Driver No 60 0.112 161 21 0.13 0
POLR3D POLR3D P05423 DNA-directed RNA polymerase III subunit RPC4 chr8 GO:0051607 Not Cancer Driver No 33 0.083 303 24 0.079 0
POLR3E POLR3E Q9NVU0 DNA-directed RNA polymerase III subunit RPC5 chr16 GO:0051607 Not Cancer Driver No 84 0.119 308 40 0.13 0
POLR3F POLR3F Q9H1D9 DNA-directed RNA polymerase III subunit RPC6 chr20 GO:0051607 Not Cancer Driver No 20 0.063 55 5 0.091 0
POLR3G POLR3G O15318 DNA-directed RNA polymerase III subunit RPC7 chr5 GO:0051607 Not Cancer Driver No 28 0.126 187 15 0.08 0
POLR3H_ENST00000396504 POLR3H Q9Y535 DNA-directed RNA polymerase III subunit RPC8 chr22 GO:0051607 Not Cancer Driver No 23 0.113 33 6 0.182 0
POLR3K POLR3K Q9Y2Y1 DNA-directed RNA polymerase III subunit RPC10 chr16 GO:0051607 Not Cancer Driver No 10 0.093 0 0 0.0 1
PQBP1_ENST00000376563 PQBP1 O60828 Polyglutamine-binding protein 1 chrX GO:0051607 Not Cancer Driver No 42 0.158 233 38 0.163 1
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0051607 Census, Compendium Yes 122 0.22 145 36 0.248 8
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0051607 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0051607 Not Cancer Driver No 16 0.082 39 4 0.103 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0051607 Compendium Yes 75 0.136 400 48 0.12 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0051607 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0051607 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNASE1_ENST00000412779 RNASE1 P07998 Ribonuclease pancreatic chr14 GO:0051607 Not Cancer Driver No 17 0.109 49 11 0.224 0
RNASE2 RNASE2 P10153 Non-secretory ribonuclease chr14 GO:0051607 Not Cancer Driver No 30 0.186 20 4 0.2 0
RNASE6 RNASE6 Q93091 Ribonuclease K6 chr14 GO:0051607 Not Cancer Driver No 26 0.173 0 0 0.0 0
RNASEL RNASEL Q05823 2-5A-dependent ribonuclease chr1 GO:0051607 Not Cancer Driver No 95 0.128 147 17 0.116 0
RNF135 RNF135 Q8IUD6 E3 ubiquitin-protein ligase RNF135 chr17 GO:0051607 Not Cancer Driver No 40 0.093 139 11 0.079 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0051607 Not Cancer Driver No 25 0.13 82 15 0.183 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0051607 Not Cancer Driver No 68 0.188 22 1 0.045 0
RTP4 RTP4 Q96DX8 Receptor-transporting protein 4 chr3 GO:0051607 Not Cancer Driver No 40 0.163 27 5 0.185 0
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0051607 Not Cancer Driver No 104 0.166 91 14 0.154 13
SENP7 SENP7 Q9BQF6 Sentrin-specific protease 7 chr3 GO:0051607 Not Cancer Driver No 149 0.142 523 73 0.14 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0051607 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0051607 Not Cancer Driver No 38 0.09 13 1 0.077 0
SETD2 SETD2 Q9BYW2 Histone-lysine N-methyltransferase SETD2 chr3 GO:0051607 Census, Compendium Yes 321 0.125 1945 209 0.107 2
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0051607 Not Cancer Driver No 52 0.123 52 6 0.115 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0051607 Not Cancer Driver No 177 0.196 34 8 0.235 0
SLFN13 SLFN13 Q68D06 Schlafen family member 13 chr17 GO:0051607 Not Cancer Driver No 152 0.169 45 5 0.111 0
SPON2_ENST00000431380 SPON2 Q9BUD6 Spondin-2 chr4 GO:0051607 Not Cancer Driver No 36 0.109 73 4 0.055 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0051607 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT2 STAT2 P52630 Signal transducer and activator of transcription 2 chr12 GO:0051607 Not Cancer Driver No 90 0.106 178 22 0.124 2
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0051607 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0051607 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0051607 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0051607 Not Cancer Driver No 182 0.173 14 1 0.071 1
TLR8_ENST00000218032 TLR8 Q9NR97 Toll-like receptor 8 chrX GO:0051607 Not Cancer Driver No 180 0.173 30 7 0.233 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0051607 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0051607 Not Cancer Driver No 46 0.121 66 13 0.197 3
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0051607 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIM11 TRIM11 Q96F44 E3 ubiquitin-protein ligase TRIM11 chr1 GO:0051607 Not Cancer Driver No 58 0.124 132 14 0.106 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0051607 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0051607 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0051607 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM22 TRIM22 Q8IYM9 E3 ubiquitin-protein ligase TRIM22 chr11 GO:0051607 Not Cancer Driver No 93 0.187 26 1 0.038 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0051607 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM26 TRIM26 Q12899 Tripartite motif-containing protein 26 chr6 GO:0051607 Not Cancer Driver No 67 0.124 153 16 0.105 0
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0051607 Census Yes 59 0.115 87 11 0.126 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0051607 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0051607 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM34_ENST00000429814 TRIM34 Q9BYJ4 Tripartite motif-containing protein 34 chr11 GO:0051607 Not Cancer Driver No 74 0.152 32 2 0.062 0
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 GO:0051607 Not Cancer Driver No 66 0.134 69 9 0.13 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0051607 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0051607 Not Cancer Driver No 71 0.144 77 11 0.143 0
TRIM52 TRIM52 Q96A61 E3 ubiquitin-protein ligase TRIM52 chr5 GO:0051607 Not Cancer Driver No 23 0.077 147 13 0.088 0
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0051607 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM8 TRIM8 Q9BZR9 E3 ubiquitin-protein ligase TRIM8 chr10 GO:0051607 Not Cancer Driver No 60 0.109 209 29 0.139 0
TTC4 TTC4 O95801 Tetratricopeptide repeat protein 4 chr1 GO:0051607 Not Cancer Driver No 45 0.116 100 12 0.12 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0051607 Not Cancer Driver No 120 0.11 248 30 0.121 0
UNC93B1 UNC93B1 Q9H1C4 Protein unc-93 homolog B1 chr11 GO:0051607 Not Cancer Driver No 57 0.095 127 5 0.039 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0051607 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0051607 Not Cancer Driver No 291 0.316 432 132 0.306 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0051607 Not Cancer Driver No 9 0.09 27 0 0.0 0
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0051607 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051607 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 GO:0051607 Not Cancer Driver No 142 0.157 344 63 0.183 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0051607 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZDHHC1 ZDHHC1 Q8WTX9 Palmitoyltransferase ZDHHC1 chr16 GO:0051607 Not Cancer Driver No 46 0.095 167 11 0.066 0
ZDHHC11 ZDHHC11 Q9H8X9 Palmitoyltransferase ZDHHC11 chr5 GO:0051607 Not Cancer Driver No 68 0.165 76 24 0.316 0
ZMYND11 ZMYND11 Q15326 Zinc finger MYND domain-containing protein 11 chr10 GO:0051607 Not Cancer Driver No 71 0.118 184 26 0.141 0
ZNF175 ZNF175 Q9Y473 Zinc finger protein 175 chr19 GO:0051607 Not Cancer Driver No 102 0.143 196 29 0.148 0
ZNFX1_ENST00000371752 ZNFX1 Q9P2E3 NFX1-type zinc finger-containing protein 1 chr20 GO:0051607 Not Cancer Driver No 228 0.119 354 49 0.138 0