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Total number of protein in "GO:0051345" GO term:  231

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0051345 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABR ABR Q12979 Active breakpoint cluster region-related protein chr17 GO:0051345 Not Cancer Driver No 122 0.142 184 36 0.196 0
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0051345 Not Cancer Driver No 54 0.151 30 3 0.1 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0051345 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0051345 Not Cancer Driver No 95 0.265 0 0 0.0 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0051345 Not Cancer Driver No 98 0.27 0 0 0.0 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051345 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0051345 Census Yes 77 0.16 84 9 0.107 2
ANG ANG P03950 Angiogenin chr14 GO:0051345 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0051345 Not Cancer Driver No 105 0.186 183 44 0.24 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0051345 Not Cancer Driver No 127 0.102 17 1 0.059 0
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0051345 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0051345 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0051345 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0051345 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0051345 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0051345 Not Cancer Driver No 67 0.194 0 0 0.0 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0051345 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 GO:0051345 Not Cancer Driver No 138 0.198 449 90 0.2 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0051345 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP25 ARHGAP25 P42331 Rho GTPase-activating protein 25 chr2 GO:0051345 Not Cancer Driver No 120 0.186 339 62 0.183 0
ARHGAP29 ARHGAP29 Q52LW3 Rho GTPase-activating protein 29 chr1 GO:0051345 Not Cancer Driver No 182 0.144 579 94 0.162 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0051345 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0051345 Not Cancer Driver No 110 0.097 679 68 0.1 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0051345 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0051345 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0051345 Not Cancer Driver No 68 0.096 297 13 0.044 0
ARHGEF19 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 GO:0051345 Not Cancer Driver No 82 0.102 365 36 0.099 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0051345 Not Cancer Driver No 164 0.188 475 86 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0051345 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL1 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 GO:0051345 Not Cancer Driver No 17 0.094 4 0 0.0 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0051345 Not Cancer Driver No 109 0.144 373 53 0.142 1
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0051345 Not Cancer Driver No 83 0.196 51 5 0.098 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0051345 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0051345 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0051345 Census Yes 30 0.156 39 2 0.051 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0051345 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0051345 Census, Compendium Yes 146 0.115 603 69 0.114 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0051345 Not Cancer Driver No 73 0.184 139 26 0.187 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0051345 Not Cancer Driver No 7 0.033 0 0 0.0 0
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0051345 Not Cancer Driver No 38 0.11 29 2 0.069 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0051345 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0051345 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0051345 Not Cancer Driver No 17 0.114 115 10 0.087 3
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0051345 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0051345 Census Yes 49 0.118 71 7 0.099 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0051345 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0051345 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0051345 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0051345 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0051345 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0051345 Not Cancer Driver No 119 0.327 177 50 0.282 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0051345 Not Cancer Driver No 43 0.219 65 16 0.246 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0051345 Not Cancer Driver No 19 0.087 23 1 0.043 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0051345 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0051345 Not Cancer Driver No 40 0.191 0 0 0.0 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0051345 Not Cancer Driver No 61 0.129 84 13 0.155 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0051345 Compendium Yes 383 0.188 151 42 0.278 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0051345 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0051345 Not Cancer Driver No 38 0.125 160 25 0.156 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0051345 Not Cancer Driver No 11 0.101 0 0 0.0 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0051345 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0051345 Not Cancer Driver No 211 0.165 86 11 0.128 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0051345 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0051345 Not Cancer Driver No 154 0.159 280 55 0.196 1
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0051345 Not Cancer Driver No 62 0.259 54 8 0.148 1
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0051345 Not Cancer Driver No 262 0.122 454 53 0.117 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0051345 Not Cancer Driver No 104 0.114 284 33 0.116 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0051345 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0051345 Not Cancer Driver No 24 0.101 31 11 0.355 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0051345 Census, Compendium Yes 444 0.367 223 35 0.157 1
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0051345 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0051345 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0051345 Not Cancer Driver No 182 0.185 140 24 0.171 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0051345 Not Cancer Driver No 70 0.088 381 27 0.071 0
EVI5_ENST00000370331 EVI5 O60447 Ecotropic viral integration site 5 protein homolog chr1 GO:0051345 Not Cancer Driver No 115 0.142 416 61 0.147 0
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0051345 Not Cancer Driver No 34 0.268 0 0 0.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0051345 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0051345 Census, Compendium Yes 55 0.164 62 18 0.29 22
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0051345 Not Cancer Driver No 193 0.263 217 44 0.203 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0051345 Not Cancer Driver No 43 0.113 92 12 0.13 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0051345 Not Cancer Driver No 25 0.059 279 18 0.065 0
GARNL3 GARNL3 Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 chr9 GO:0051345 Not Cancer Driver No 115 0.114 285 34 0.119 0
GBA3 GBA3 Q9H227 Cytosolic beta-glucosidase chr4 GO:0051345 Not Cancer Driver No 118 0.252 18 6 0.333 0
GMIP GMIP Q9P107 GEM-interacting protein chr19 GO:0051345 Not Cancer Driver No 124 0.128 597 67 0.112 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0051345 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0051345 Compendium Yes 52 0.138 32 4 0.125 0
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0051345 Not Cancer Driver No 43 0.123 39 6 0.154 3
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0051345 Not Cancer Driver No 26 0.141 82 15 0.183 10
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0051345 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0051345 Not Cancer Driver No 70 0.208 0 0 0.0 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0051345 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRN GRN P28799 Progranulin chr17 GO:0051345 Not Cancer Driver No 76 0.128 29 6 0.207 1
GRTP1_ENST00000375431 GRTP1 Q5TC63 Growth hormone-regulated TBC protein 1 chr13 GO:0051345 Not Cancer Driver No 58 0.173 39 3 0.077 0
GSN GSN P06396 Gelsolin chr9 GO:0051345 Not Cancer Driver No 76 0.097 316 28 0.089 2
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0051345 Not Cancer Driver No 38 0.182 207 38 0.184 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0051345 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0051345 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0051345 Not Cancer Driver No 24 0.037 200 13 0.065 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0051345 Compendium Yes 44 0.096 127 9 0.071 2
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0051345 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0051345 Not Cancer Driver No 51 0.307 23 6 0.261 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0051345 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0051345 Not Cancer Driver No 166 0.141 26 0 0.0 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0051345 Census, Compendium Yes 136 0.12 59 5 0.085 5
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051345 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0051345 Not Cancer Driver No 57 0.132 112 19 0.17 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051345 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0051345 Census Yes 95 0.186 84 12 0.143 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0051345 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0051345 Not Cancer Driver No 64 0.15 94 9 0.096 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0051345 Not Cancer Driver No 52 0.171 304 52 0.171 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0051345 Not Cancer Driver No 92 0.195 408 81 0.199 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0051345 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0051345 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0051345 Not Cancer Driver No 62 0.083 582 49 0.084 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0051345 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0051345 Not Cancer Driver No 106 0.127 516 72 0.14 0
NGEF NGEF Q8N5V2 Ephexin-1 chr2 GO:0051345 Not Cancer Driver No 125 0.176 296 34 0.115 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0051345 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0051345 Not Cancer Driver No 106 0.119 203 28 0.138 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0051345 Not Cancer Driver No 139 0.335 5 1 0.2 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0051345 Not Cancer Driver No 90 0.159 218 33 0.151 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0051345 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0051345 Not Cancer Driver No 56 0.125 146 13 0.089 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0051345 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0051345 Census, Compendium Yes 249 0.297 57 21 0.368 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0051345 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0051345 Census, Compendium Yes 164 0.148 231 44 0.19 7
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0051345 Not Cancer Driver No 28 0.145 0 0 0.0 1
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0051345 Census Yes 89 0.137 320 42 0.131 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0051345 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0051345 Not Cancer Driver No 74 0.132 216 29 0.134 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0051345 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 GO:0051345 Not Cancer Driver No 78 0.098 150 14 0.093 2
PLEK PLEK P08567 Pleckstrin chr2 GO:0051345 Not Cancer Driver No 81 0.231 39 9 0.231 0
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0051345 Not Cancer Driver No 124 0.267 32 11 0.344 1
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0051345 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0051345 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0051345 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0051345 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0051345 Not Cancer Driver No 72 0.101 415 45 0.108 1
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0051345 Compendium Yes 79 0.117 43 9 0.209 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0051345 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0051345 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0051345 Compendium Yes 118 0.134 246 34 0.138 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0051345 Not Cancer Driver No 10 0.036 199 6 0.03 0
PSAP PSAP P07602 Prosaposin chr10 GO:0051345 Not Cancer Driver No 59 0.113 28 2 0.071 8
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0051345 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0051345 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0051345 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0051345 Not Cancer Driver No 16 0.082 39 4 0.103 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 GO:0051345 Not Cancer Driver No 114 0.107 407 40 0.098 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 GO:0051345 Not Cancer Driver No 116 0.142 235 33 0.14 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0051345 Not Cancer Driver No 34 0.107 13 0 0.0 0
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 GO:0051345 Not Cancer Driver No 227 0.111 649 73 0.112 1
RALGAPA2 RALGAPA2 Q2PPJ7 Ral GTPase-activating protein subunit alpha-2 chr20 GO:0051345 Not Cancer Driver No 243 0.13 415 66 0.159 0
RALGAPB_ENST00000397040 RALGAPB Q86X10 Ral GTPase-activating protein subunit beta chr20 GO:0051345 Not Cancer Driver No 202 0.135 376 54 0.144 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0051345 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAP1GAP2 RAP1GAP2 Q684P5 Rap1 GTPase-activating protein 2 chr17 GO:0051345 Not Cancer Driver No 93 0.127 413 57 0.138 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0051345 Not Cancer Driver No 81 0.122 313 39 0.125 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0051345 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0051345 Not Cancer Driver No 96 0.12 191 12 0.063 1
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0051345 Not Cancer Driver No 63 0.121 194 27 0.139 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0051345 Not Cancer Driver No 73 0.23 28 5 0.179 0
RGN RGN Q15493 Regucalcin chrX GO:0051345 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0051345 Not Cancer Driver No 26 0.136 22 5 0.227 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0051345 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0051345 Not Cancer Driver No 66 0.127 295 39 0.132 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0051345 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0051345 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0051345 Not Cancer Driver No 22 0.091 48 4 0.083 0
RUNDC1 RUNDC1 Q96C34 RUN domain-containing protein 1 chr17 GO:0051345 Not Cancer Driver No 65 0.106 238 21 0.088 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0051345 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0051345 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0051345 Not Cancer Driver No 147 0.253 561 145 0.258 0
SGSM1 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0051345 Not Cancer Driver No 206 0.179 418 68 0.163 0
SGSM2_ENST00000426855 SGSM2 O43147 Small G protein signaling modulator 2 chr17 GO:0051345 Not Cancer Driver No 83 0.083 316 21 0.066 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0051345 Not Cancer Driver No 83 0.111 77 9 0.117 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0051345 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SIPA1L2 SIPA1L2 Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 chr1 GO:0051345 Not Cancer Driver No 311 0.181 895 172 0.192 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 GO:0051345 Not Cancer Driver No 273 0.153 1257 190 0.151 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0051345 Not Cancer Driver No 67 0.064 666 43 0.065 0
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0051345 Not Cancer Driver No 83 0.129 27 3 0.111 5
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0051345 Not Cancer Driver No 111 0.134 417 63 0.151 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0051345 Census, Compendium Yes 97 0.228 111 19 0.171 5
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0051345 Not Cancer Driver No 330 0.315 820 282 0.344 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0051345 Census, Compendium Yes 110 0.143 152 15 0.099 19
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0051345 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYDE2 SYDE2 Q5VT97 Rho GTPase-activating protein SYDE2 chr1 GO:0051345 Not Cancer Driver No 136 0.114 693 69 0.1 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0051345 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 GO:0051345 Not Cancer Driver No 16 0.129 51 8 0.157 0
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 GO:0051345 Not Cancer Driver No 138 0.118 455 58 0.127 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0051345 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 GO:0051345 Not Cancer Driver No 54 0.067 498 27 0.054 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0051345 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBC1D12 TBC1D12 O60347 TBC1 domain family member 12 chr10 GO:0051345 Not Cancer Driver No 62 0.08 458 20 0.044 0
TBC1D13 TBC1D13 Q9NVG8 TBC1 domain family member 13 chr9 GO:0051345 Not Cancer Driver No 49 0.122 57 10 0.175 0
TBC1D14 TBC1D14 Q9P2M4 TBC1 domain family member 14 chr4 GO:0051345 Not Cancer Driver No 80 0.115 311 36 0.116 0
TBC1D15 TBC1D15 Q8TC07 TBC1 domain family member 15 chr12 GO:0051345 Not Cancer Driver No 90 0.13 135 23 0.17 0
TBC1D16 TBC1D16 Q8TBP0 TBC1 domain family member 16 chr17 GO:0051345 Not Cancer Driver No 84 0.11 307 37 0.121 0
TBC1D17 TBC1D17 Q9HA65 TBC1 domain family member 17 chr19 GO:0051345 Not Cancer Driver No 76 0.117 191 25 0.131 0
TBC1D2 TBC1D2 Q9BYX2 TBC1 domain family member 2A chr9 GO:0051345 Not Cancer Driver No 106 0.114 338 39 0.115 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0051345 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBC1D22A TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 GO:0051345 Not Cancer Driver No 84 0.162 219 23 0.105 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 GO:0051345 Not Cancer Driver No 55 0.109 205 27 0.132 0
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX GO:0051345 Not Cancer Driver No 114 0.166 256 37 0.145 0
TBC1D26 TBC1D26 Q86UD7 TBC1 domain family member 26 chr17 GO:0051345 Not Cancer Driver No 34 0.136 66 7 0.106 0
TBC1D28 TBC1D28 Q2M2D7 TBC1 domain family member 28 chr17 GO:0051345 Not Cancer Driver No 36 0.171 61 12 0.197 0
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 GO:0051345 Not Cancer Driver No 118 0.123 419 43 0.103 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0051345 Not Cancer Driver No 173 0.133 590 90 0.153 0
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0051345 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0051345 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBC1D8B TBC1D8B Q0IIM8 TBC1 domain family member 8B chrX GO:0051345 Not Cancer Driver No 197 0.176 134 21 0.157 2
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 GO:0051345 Not Cancer Driver No 164 0.144 224 28 0.125 0
TBC1D9 TBC1D9 Q6ZT07 TBC1 domain family member 9 chr4 GO:0051345 Not Cancer Driver No 196 0.155 295 57 0.193 0
TBC1D9B TBC1D9B Q66K14 TBC1 domain family member 9B chr5 GO:0051345 Not Cancer Driver No 142 0.114 346 34 0.098 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0051345 Not Cancer Driver No 115 0.129 88 9 0.102 2
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0051345 Compendium Yes 61 0.18 285 52 0.182 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0051345 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIAM2 TIAM2 Q8IVF5 Rho guanine nucleotide exchange factor TIAM2 chr6 GO:0051345 Not Cancer Driver No 309 0.182 779 166 0.213 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 GO:0051345 Not Cancer Driver No 31 0.113 56 4 0.071 1
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051345 Not Cancer Driver No 24 0.103 45 3 0.067 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0051345 Census, Compendium Yes 135 0.116 732 78 0.107 11
USP6 USP6 P35125 Ubiquitin carboxyl-terminal hydrolase 6 chr17 GO:0051345 Census, Compendium Yes 243 0.173 537 83 0.155 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 GO:0051345 Not Cancer Driver No 113 0.136 472 81 0.172 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0051345 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0051345 Not Cancer Driver No 27 0.116 41 7 0.171 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0051345 Not Cancer Driver No 65 0.137 180 18 0.1 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0051345 Not Cancer Driver No 66 0.174 0 0 0.0 2
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0051345 Census, Compendium Yes 164 0.115 373 41 0.11 2