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Total number of protein in "GO:0051254" GO term:  267

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0051254 Not Cancer Driver No 126 0.147 141 15 0.106 11
APLN APLN Q9ULZ1 Apelin chrX GO:0051254 Not Cancer Driver No 8 0.104 51 6 0.118 0
AR AR P10275 Androgen receptor chrX GO:0051254 Census, Compendium Yes 196 0.213 443 88 0.199 169
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0051254 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0051254 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0051254 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0051254 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0051254 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0051254 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0051254 Census, Compendium Yes 487 0.195 1672 301 0.18 33
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0051254 Not Cancer Driver No 153 0.103 840 87 0.104 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0051254 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0051254 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0051254 Census, Compendium Yes 66 0.124 21 0 0.0 8
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0051254 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:0051254 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0051254 Not Cancer Driver No 90 0.133 399 45 0.113 4
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0051254 Census Yes 32 0.203 7 2 0.286 0
BUD23_ENST00000265758 BUD23 O43709 Probable 18S rRNA (guanine-N(7))-methyltransferase chr7 GO:0051254 Not Cancer Driver No 41 0.146 83 11 0.133 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0051254 Not Cancer Driver No 93 0.128 503 63 0.125 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0051254 Census, Compendium Yes 110 0.207 210 39 0.186 2
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0051254 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0051254 Not Cancer Driver No 3 0.009 276 2 0.007 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0051254 Not Cancer Driver No 56 0.115 166 17 0.102 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0051254 Not Cancer Driver No 82 0.176 201 33 0.164 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0051254 Not Cancer Driver No 107 0.22 253 74 0.292 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0051254 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0051254 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0051254 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 GO:0051254 Not Cancer Driver No 19 0.11 129 13 0.101 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0051254 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0051254 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0051254 Not Cancer Driver No 30 0.103 6 0 0.0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0051254 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0051254 Census, Compendium Yes 66 0.095 414 28 0.068 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0051254 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0051254 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0051254 Not Cancer Driver No 96 0.208 338 67 0.198 1
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 GO:0051254 Compendium Yes 53 0.13 327 45 0.138 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0051254 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0051254 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0051254 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0051254 Census Yes 74 0.121 225 23 0.102 0
DEK DEK P35659 Protein DEK chr6 GO:0051254 Census Yes 47 0.125 297 41 0.138 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0051254 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0051254 Not Cancer Driver No 159 0.158 222 39 0.176 0
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 GO:0051254 Not Cancer Driver No 28 0.089 37 2 0.054 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0051254 Not Cancer Driver No 114 0.129 264 22 0.083 1
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0051254 Not Cancer Driver No 71 0.246 223 57 0.256 1
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:0051254 Not Cancer Driver No 23 0.065 36 0 0.0 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0051254 Not Cancer Driver No 46 0.116 143 17 0.119 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0051254 Not Cancer Driver No 135 0.177 447 73 0.163 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0051254 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0051254 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0051254 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0051254 Not Cancer Driver No 116 0.118 899 101 0.112 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0051254 Census, Compendium Yes 67 0.108 446 53 0.119 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0051254 Census, Compendium Yes 334 0.138 1790 196 0.109 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0051254 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0051254 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0051254 Not Cancer Driver No 125 0.128 250 28 0.112 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0051254 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0051254 Not Cancer Driver No 68 0.154 78 9 0.115 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0051254 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0051254 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0051254 Not Cancer Driver No 58 0.132 154 18 0.117 1
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0051254 Not Cancer Driver No 18 0.062 183 5 0.027 0
FOS FOS P01100 Protein c-Fos chr14 GO:0051254 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0051254 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0051254 Compendium Yes 70 0.153 258 34 0.132 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0051254 Census, Compendium Yes 70 0.104 595 68 0.114 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0051254 Not Cancer Driver No 67 0.133 53 10 0.189 3
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0051254 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0051254 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0051254 Not Cancer Driver No 40 0.101 268 24 0.09 9
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0051254 Not Cancer Driver No 327 0.122 117 16 0.137 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0051254 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0051254 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0051254 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0051254 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0051254 Not Cancer Driver No 32 0.143 77 14 0.182 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0051254 Not Cancer Driver No 56 0.102 257 21 0.082 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0051254 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 GO:0051254 Not Cancer Driver No 49 0.102 147 20 0.136 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0051254 Not Cancer Driver No 75 0.112 263 26 0.099 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 GO:0051254 Not Cancer Driver No 32 0.077 413 32 0.077 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0051254 Not Cancer Driver No 47 0.217 124 29 0.234 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:0051254 Not Cancer Driver No 291 0.136 43 5 0.116 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0051254 Census Yes 118 0.143 435 51 0.117 0
HMX2 HMX2 A2RU54 Homeobox protein HMX2 chr10 GO:0051254 Not Cancer Driver No 36 0.132 169 21 0.124 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0051254 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPLL HNRNPLL Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like chr2 GO:0051254 Not Cancer Driver No 37 0.068 149 13 0.087 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0051254 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0051254 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0051254 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0051254 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0051254 Not Cancer Driver No 149 0.231 251 52 0.207 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0051254 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0051254 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0051254 Not Cancer Driver No 14 0.104 52 7 0.135 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0051254 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0051254 Not Cancer Driver No 35 0.165 58 7 0.121 0
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0051254 Not Cancer Driver No 55 0.112 43 3 0.07 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0051254 Not Cancer Driver No 292 0.275 114 26 0.228 1
JUN JUN P05412 Transcription factor Jun chr1 GO:0051254 Census Yes 35 0.106 281 25 0.089 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0051254 Not Cancer Driver No 84 0.118 684 81 0.118 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0051254 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0051254 Compendium Yes 77 0.168 366 40 0.109 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0051254 Not Cancer Driver No 58 0.1 350 44 0.126 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0051254 Not Cancer Driver No 74 0.111 611 69 0.113 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0051254 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0051254 Not Cancer Driver No 60 0.24 179 32 0.179 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0051254 Not Cancer Driver No 50 0.132 249 31 0.124 0
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0051254 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0051254 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0051254 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0051254 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0051254 Census Yes 58 0.145 105 14 0.133 4
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0051254 Not Cancer Driver No 92 0.113 490 50 0.102 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0051254 Not Cancer Driver No 91 0.101 151 16 0.106 8
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0051254 Not Cancer Driver No 63 0.121 16 4 0.25 9
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0051254 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0051254 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0051254 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0051254 Not Cancer Driver No 74 0.128 274 29 0.106 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:0051254 Not Cancer Driver No 35 0.054 501 24 0.048 0
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0051254 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0051254 Not Cancer Driver No 110 0.11 101 8 0.079 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:0051254 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0051254 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0051254 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0051254 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0051254 Census Yes 40 0.032 1050 19 0.018 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0051254 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 GO:0051254 Census, Compendium Yes 71 0.153 415 64 0.154 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0051254 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0051254 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0051254 Census Yes 45 0.141 246 33 0.134 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0051254 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0051254 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0051254 Not Cancer Driver No 31 0.179 117 25 0.214 0
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0051254 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCL NCL P19338 Nucleolin chr2 GO:0051254 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0051254 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0051254 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0051254 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0051254 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0051254 Not Cancer Driver No 48 0.148 181 22 0.122 55
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:0051254 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0051254 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0051254 Not Cancer Driver No 336 0.168 464 79 0.17 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0051254 Not Cancer Driver No 90 0.159 218 33 0.151 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0051254 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0051254 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0051254 Not Cancer Driver No 92 0.118 362 37 0.102 12
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0051254 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 GO:0051254 Census Yes 227 0.125 1008 107 0.106 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0051254 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0051254 Not Cancer Driver No 77 0.145 378 56 0.148 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0051254 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0051254 Census Yes 37 0.154 99 22 0.222 2
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0051254 Not Cancer Driver No 154 0.145 603 93 0.154 1
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0051254 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0051254 Census, Compendium Yes 154 0.213 268 61 0.228 2
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:0051254 Not Cancer Driver No 59 0.097 369 37 0.1 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0051254 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0051254 Not Cancer Driver No 15 0.087 15 1 0.067 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0051254 Census Yes 72 0.143 44 4 0.091 3
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0051254 Not Cancer Driver No 46 0.205 13 4 0.308 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0051254 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0051254 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRL PRL P01236 Prolactin chr6 GO:0051254 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0051254 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0051254 Not Cancer Driver No 57 0.155 108 12 0.111 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0051254 Not Cancer Driver No 150 0.126 640 77 0.12 3
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0051254 Not Cancer Driver No 51 0.102 186 22 0.118 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0051254 Not Cancer Driver No 31 0.128 40 6 0.15 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0051254 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM20 RBM20 Q5T481 RNA-binding protein 20 chr10 GO:0051254 Not Cancer Driver No 55 0.045 957 41 0.043 10
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:0051254 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0051254 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX GO:0051254 Not Cancer Driver No 22 0.14 134 18 0.134 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0051254 Not Cancer Driver No 82 0.21 380 81 0.213 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 GO:0051254 Not Cancer Driver No 77 0.197 371 75 0.202 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0051254 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0051254 Not Cancer Driver No 158 0.139 796 115 0.144 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0051254 Compendium Yes 75 0.136 400 48 0.12 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0051254 Not Cancer Driver No 20 0.146 3 0 0.0 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:0051254 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 GO:0051254 Not Cancer Driver No 68 0.123 253 33 0.13 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0051254 Compendium Yes 82 0.122 277 39 0.141 4
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0051254 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0051254 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0051254 Not Cancer Driver No 176 0.132 241 21 0.087 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0051254 Not Cancer Driver No 83 0.159 447 73 0.163 47
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0051254 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0051254 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:0051254 Census, Compendium Yes 244 0.187 477 80 0.168 0
SF3B4 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 GO:0051254 Not Cancer Driver No 69 0.163 273 56 0.205 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0051254 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 GO:0051254 Not Cancer Driver No 60 0.119 9 1 0.111 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0051254 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0051254 Not Cancer Driver No 67 0.124 139 18 0.129 1
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0051254 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0051254 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0051254 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0051254 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0051254 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0051254 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0051254 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0051254 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0051254 Census, Compendium Yes 64 0.166 141 35 0.248 3
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0051254 Not Cancer Driver No 38 0.087 416 37 0.089 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0051254 Not Cancer Driver No 62 0.116 488 56 0.115 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0051254 Not Cancer Driver No 46 0.17 187 34 0.182 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0051254 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0051254 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0051254 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 GO:0051254 Not Cancer Driver No 50 0.184 189 40 0.212 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0051254 Census, Compendium Yes 110 0.143 152 15 0.099 19
STH STH Q8IWL8 Saitohin chr17 GO:0051254 Not Cancer Driver No 13 0.102 55 5 0.091 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0051254 Not Cancer Driver No 72 0.092 140 12 0.086 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0051254 Not Cancer Driver No 51 0.123 202 15 0.074 27
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0051254 Not Cancer Driver No 110 0.253 253 69 0.273 1
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0051254 Not Cancer Driver No 52 0.122 157 24 0.153 1
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0051254 Census Yes 110 0.097 212 16 0.075 31
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0051254 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0051254 Not Cancer Driver No 63 0.152 47 8 0.17 3
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 GO:0051254 Census Yes 137 0.143 955 137 0.143 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051254 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0051254 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:0051254 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:0051254 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:0051254 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0051254 Not Cancer Driver No 35 0.101 214 18 0.084 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0051254 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 GO:0051254 Not Cancer Driver No 45 0.16 253 41 0.162 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0051254 Not Cancer Driver No 59 0.205 244 54 0.221 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0051254 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 GO:0051254 Not Cancer Driver No 15 0.12 17 2 0.118 0
TTC5 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0051254 Not Cancer Driver No 65 0.148 151 19 0.126 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0051254 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0051254 Not Cancer Driver No 159 0.106 659 74 0.112 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 GO:0051254 Compendium Yes 78 0.164 191 28 0.147 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0051254 Not Cancer Driver No 100 0.131 567 77 0.136 1
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0051254 Not Cancer Driver No 146 0.129 329 36 0.109 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0051254 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0051254 Not Cancer Driver No 30 0.087 326 29 0.089 0
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:0051254 Not Cancer Driver No 49 0.095 39 4 0.103 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0051254 Not Cancer Driver No 27 0.116 41 7 0.171 0
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:0051254 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:0051254 Not Cancer Driver No 67 0.081 87 7 0.08 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0051254 Not Cancer Driver No 19 0.073 169 9 0.053 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0051254 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0051254 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0051254 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051254 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0051254 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 GO:0051254 Not Cancer Driver No 139 0.146 929 134 0.144 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0051254 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 GO:0051254 Not Cancer Driver No 142 0.157 344 63 0.183 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0051254 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0051254 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0051254 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0051254 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0051254 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZSWIM8_ENST00000605216 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 GO:0051254 Not Cancer Driver No 204 0.111 877 103 0.117 0