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Total number of protein in "GO:0051247" GO term:  829

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0051247 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0051247 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0051247 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0051247 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0051247 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0051247 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0051247 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0051247 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0051247 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0051247 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0051247 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0051247 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0051247 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0051247 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0051247 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0051247 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0051247 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0051247 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0051247 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0051247 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0051247 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0051247 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0051247 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGT AGT P01019 Angiotensinogen chr1 GO:0051247 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0051247 Not Cancer Driver No 98 0.27 0 0 0.0 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 GO:0051247 Not Cancer Driver No 46 0.144 61 8 0.131 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0051247 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 GO:0051247 Not Cancer Driver No 76 0.118 510 61 0.12 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0051247 Census Yes 474 0.121 2281 268 0.117 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0051247 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:0051247 Not Cancer Driver No 90 0.19 0 0 0.0 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0051247 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0051247 Not Cancer Driver No 7 0.046 31 0 0.0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0051247 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMER1 AMER1 Q5JTC6 APC membrane recruitment protein 1 chrX GO:0051247 Census, Compendium Yes 234 0.206 1039 219 0.211 0
ANG ANG P03950 Angiogenin chr14 GO:0051247 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0051247 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0051247 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 GO:0051247 Not Cancer Driver No 17 0.086 26 6 0.231 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0051247 Not Cancer Driver No 127 0.135 521 71 0.136 2
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0051247 Not Cancer Driver No 105 0.186 183 44 0.24 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0051247 Not Cancer Driver No 49 0.145 20 4 0.2 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0051247 Not Cancer Driver No 127 0.102 17 1 0.059 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0051247 Not Cancer Driver No 96 0.253 29 8 0.276 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0051247 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0051247 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0051247 Census, Compendium Yes 84 0.139 181 32 0.177 0
AREG AREG P15514 Amphiregulin chr4 GO:0051247 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0051247 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0051247 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0051247 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0051247 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0051247 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0051247 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0051247 Not Cancer Driver No 46 0.112 122 22 0.18 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 GO:0051247 Not Cancer Driver No 52 0.126 95 12 0.126 0
ARRDC4 ARRDC4 Q8NCT1 Arrestin domain-containing protein 4 chr15 GO:0051247 Not Cancer Driver No 52 0.124 53 12 0.226 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0051247 Not Cancer Driver No 109 0.144 373 53 0.142 1
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0051247 Not Cancer Driver No 101 0.234 179 44 0.246 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0051247 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0051247 Not Cancer Driver No 46 0.127 181 24 0.133 0
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0051247 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0051247 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0051247 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZU1 AZU1 P20160 Azurocidin chr19 GO:0051247 Not Cancer Driver No 42 0.167 53 13 0.245 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0051247 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 GO:0051247 Not Cancer Driver No 17 0.081 112 9 0.08 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0051247 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0051247 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0051247 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0051247 Census Yes 30 0.156 39 2 0.051 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0051247 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0051247 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0051247 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0051247 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0051247 Census, Compendium Yes 134 0.19 328 67 0.204 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0051247 Not Cancer Driver No 47 0.19 79 19 0.241 1
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0051247 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0051247 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0051247 Not Cancer Driver No 52 0.174 136 22 0.162 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 GO:0051247 Not Cancer Driver No 79 0.335 39 10 0.256 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0051247 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0051247 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0051247 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0051247 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0051247 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0051247 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0051247 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0051247 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0051247 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0051247 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0051247 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0051247 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0051247 Compendium Yes 141 0.136 601 70 0.116 19
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0051247 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0051247 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0051247 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0051247 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 GO:0051247 Compendium Yes 82 0.126 482 57 0.118 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 GO:0051247 Not Cancer Driver No 42 0.171 115 18 0.157 0
BTC BTC P35070 Probetacellulin chr4 GO:0051247 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0051247 Not Cancer Driver No 80 0.132 45 4 0.089 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0051247 Not Cancer Driver No 14 0.05 103 6 0.058 2
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0051247 Not Cancer Driver No 38 0.11 29 2 0.069 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0051247 Not Cancer Driver No 31 0.091 43 5 0.116 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0051247 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0051247 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0051247 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0051247 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0051247 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0051247 Census, Compendium Yes 300 0.179 883 152 0.172 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0051247 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0051247 Not Cancer Driver No 99 0.099 296 36 0.122 11
CARD9 CARD9 Q9H257 Caspase recruitment domain-containing protein 9 chr9 GO:0051247 Not Cancer Driver No 72 0.134 225 35 0.156 11
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0051247 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0051247 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0051247 Census Yes 49 0.118 71 7 0.099 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0051247 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0051247 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0051247 Census Yes 160 0.163 562 104 0.185 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0051247 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0051247 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0051247 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0051247 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0051247 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0051247 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0051247 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0051247 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0051247 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0051247 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0051247 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0051247 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0051247 Not Cancer Driver No 31 0.086 100 8 0.08 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0051247 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0051247 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0051247 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0051247 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0051247 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0051247 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0051247 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0051247 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0051247 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0051247 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0051247 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDCA2 CDCA2 Q69YH5 Cell division cycle-associated protein 2 chr8 GO:0051247 Not Cancer Driver No 124 0.121 828 100 0.121 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0051247 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0051247 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0051247 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0051247 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0051247 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0051247 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0051247 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0051247 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0051247 Not Cancer Driver No 207 0.152 105 10 0.095 0
CENPS CENPS Q8N2Z9 Centromere protein S chr1 GO:0051247 Not Cancer Driver No 16 0.116 65 7 0.108 0
CENPX_ENST00000392359 CENPX A8MT69 Centromere protein X chr17 GO:0051247 Not Cancer Driver No 4 0.049 0 0 0.0 0
CEP295 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 GO:0051247 Not Cancer Driver No 115 0.044 2026 87 0.043 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0051247 Not Cancer Driver No 85 0.128 341 54 0.158 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0051247 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0051247 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0051247 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0051247 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0051247 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0051247 Not Cancer Driver No 19 0.087 23 1 0.043 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0051247 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0051247 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0051247 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0051247 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLEC3B CLEC3B P05452 Tetranectin chr3 GO:0051247 Not Cancer Driver No 34 0.168 50 13 0.26 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0051247 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0051247 Census Yes 11 0.062 19 0 0.0 0
CNEP1R1_ENST00000427478 CNEP1R1 Q8N9A8 Nuclear envelope phosphatase-regulatory subunit 1 chr16 GO:0051247 Not Cancer Driver No 8 0.064 0 0 0.0 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0051247 Compendium Yes 42 0.14 30 0 0.0 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0051247 Not Cancer Driver No 155 0.149 370 61 0.165 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:0051247 Not Cancer Driver No 4 0.038 57 3 0.053 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 GO:0051247 Not Cancer Driver No 21 0.111 17 0 0.0 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0051247 Not Cancer Driver No 25 0.12 14 2 0.143 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0051247 Compendium Yes 383 0.188 151 42 0.278 0
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0051247 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0051247 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0051247 Not Cancer Driver No 118 0.148 204 29 0.142 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0051247 Census Yes 133 0.137 124 17 0.137 20
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0051247 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0051247 Not Cancer Driver No 20 0.093 19 0 0.0 4
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 GO:0051247 Not Cancer Driver No 42 0.095 123 9 0.073 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0051247 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0051247 Not Cancer Driver No 164 0.14 385 48 0.125 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0051247 Census, Compendium Yes 123 0.16 167 23 0.138 3
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0051247 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0051247 Not Cancer Driver No 80 0.225 0 0 0.0 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0051247 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0051247 Not Cancer Driver No 211 0.165 86 11 0.128 3
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0051247 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0051247 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0051247 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0051247 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0051247 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0051247 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0051247 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0051247 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0051247 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX58 DDX58 O95786 Antiviral innate immune response receptor RIG-I chr9 GO:0051247 Not Cancer Driver No 118 0.128 61 10 0.164 2
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0051247 Not Cancer Driver No 28 0.112 11 1 0.091 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0051247 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0051247 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0051247 Compendium Yes 182 0.143 331 42 0.127 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0051247 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0051247 Not Cancer Driver No 204 0.13 396 53 0.134 0
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0051247 Not Cancer Driver No 181 0.115 375 49 0.131 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0051247 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0051247 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0051247 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0051247 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0051247 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMRTC2 DMRTC2 Q8IXT2 Doublesex- and mab-3-related transcription factor C2 chr19 GO:0051247 Not Cancer Driver No 45 0.123 310 35 0.113 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0051247 Not Cancer Driver No 60 0.119 131 17 0.13 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0051247 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 GO:0051247 Not Cancer Driver No 153 0.179 328 71 0.216 16
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0051247 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0051247 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0051247 Not Cancer Driver No 52 0.103 286 27 0.094 19
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0051247 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0051247 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0051247 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0051247 Not Cancer Driver No 54 0.257 78 21 0.269 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0051247 Not Cancer Driver No 135 0.177 447 73 0.163 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0051247 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0051247 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0051247 Not Cancer Driver No 24 0.101 31 11 0.355 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0051247 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0051247 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0051247 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0051247 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0051247 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:0051247 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:0051247 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0051247 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0051247 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:0051247 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0051247 Not Cancer Driver No 37 0.24 21 5 0.238 5
ENG ENG P17813 Endoglin chr9 GO:0051247 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0051247 Not Cancer Driver No 51 0.118 21 2 0.095 0
EPGN EPGN Q6UW88 Epigen chr4 GO:0051247 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0051247 Not Cancer Driver No 182 0.185 140 24 0.171 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0051247 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0051247 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0051247 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0051247 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0051247 Not Cancer Driver No 192 0.207 213 45 0.211 0
F12 F12 P00748 Coagulation factor XII chr5 GO:0051247 Not Cancer Driver No 53 0.086 104 9 0.087 13
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0051247 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0051247 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM161A_ENST00000405894 FAM161A Q3B820 Protein FAM161A chr2 GO:0051247 Not Cancer Driver No 102 0.155 510 83 0.163 0
FAM47E FAM47E Q6ZV65 Protein FAM47E chr4 GO:0051247 Not Cancer Driver No 21 0.053 143 6 0.042 0
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 GO:0051247 Not Cancer Driver No 161 0.121 129 20 0.155 2
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0051247 Not Cancer Driver No 268 0.131 898 128 0.143 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0051247 Census, Compendium Yes 55 0.164 62 18 0.29 22
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0051247 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:0051247 Not Cancer Driver No 106 0.16 6 1 0.167 0
FBXO33 FBXO33 Q7Z6M2 F-box only protein 33 chr14 GO:0051247 Not Cancer Driver No 38 0.068 30 2 0.067 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0051247 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0051247 Census, Compendium Yes 322 0.455 230 38 0.165 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0051247 Not Cancer Driver No 68 0.114 120 4 0.033 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0051247 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0051247 Not Cancer Driver No 193 0.263 217 44 0.203 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0051247 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0051247 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0051247 Not Cancer Driver No 30 0.194 29 2 0.069 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0051247 Not Cancer Driver No 15 0.139 39 7 0.179 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0051247 Not Cancer Driver No 124 0.196 327 70 0.214 3
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0051247 Not Cancer Driver No 143 0.123 384 44 0.115 0
FNIP2 FNIP2 Q9P278 Folliculin-interacting protein 2 chr4 GO:0051247 Not Cancer Driver No 119 0.107 555 71 0.128 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0051247 Not Cancer Driver No 43 0.113 92 12 0.13 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0051247 Not Cancer Driver No 38 0.088 186 16 0.086 10
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0051247 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0051247 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0051247 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0051247 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0051247 Not Cancer Driver No 72 0.104 146 3 0.021 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0051247 Not Cancer Driver No 74 0.149 184 30 0.163 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0051247 Not Cancer Driver No 9 0.077 11 0 0.0 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0051247 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0051247 Census, Compendium Yes 111 0.251 364 87 0.239 2
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0051247 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCG GCG P01275 Pro-glucagon chr2 GO:0051247 Not Cancer Driver No 49 0.272 82 22 0.268 0
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0051247 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0051247 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0051247 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0051247 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0051247 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0051247 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0051247 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0051247 Not Cancer Driver No 72 0.159 53 15 0.283 0
GH1 GH1 P01241 Somatotropin chr17 GO:0051247 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0051247 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0051247 Not Cancer Driver No 173 0.271 229 66 0.288 19
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 GO:0051247 Not Cancer Driver No 87 0.157 201 27 0.134 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0051247 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0051247 Not Cancer Driver No 56 0.102 257 21 0.082 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0051247 Not Cancer Driver No 115 0.115 854 96 0.112 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0051247 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0051247 Not Cancer Driver No 89 0.156 94 18 0.191 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0051247 Not Cancer Driver No 82 0.203 75 19 0.253 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0051247 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0051247 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0051247 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0051247 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSAP GSAP A4D1B5 Gamma-secretase-activating protein chr7 GO:0051247 Not Cancer Driver No 89 0.104 13 0 0.0 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0051247 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSN GSN P06396 Gelsolin chr9 GO:0051247 Not Cancer Driver No 76 0.097 316 28 0.089 2
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0051247 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0051247 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX GO:0051247 Not Cancer Driver No 280 0.138 1345 181 0.135 1
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0051247 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0051247 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0051247 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0051247 Not Cancer Driver No 178 0.147 409 59 0.144 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0051247 Census Yes 38 0.097 248 17 0.069 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0051247 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIST1H1B H1-5 P16401 Histone H1.5 chr6 GO:0051247 Not Cancer Driver No 66 0.292 224 66 0.295 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0051247 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0051247 Not Cancer Driver No 77 0.093 504 45 0.089 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0051247 Not Cancer Driver No 60 0.144 12 0 0.0 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0051247 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0051247 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0051247 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 GO:0051247 Not Cancer Driver No 29 0.081 130 7 0.054 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0051247 Compendium Yes 44 0.096 127 9 0.071 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0051247 Not Cancer Driver No 669 0.153 2091 329 0.157 21
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0051247 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0051247 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0051247 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0051247 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0051247 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0051247 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0051247 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0051247 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0051247 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0051247 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0051247 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0051247 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0051247 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0051247 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0051247 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0051247 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0051247 Compendium Yes 55 0.112 175 22 0.126 10
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0051247 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0051247 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0051247 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0051247 Not Cancer Driver No 141 0.244 298 80 0.268 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0051247 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0051247 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0051247 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17D IL17D Q8TAD2 Interleukin-17D chr13 GO:0051247 Not Cancer Driver No 9 0.045 64 1 0.016 0
IL17F IL17F Q96PD4 Interleukin-17F chr6 GO:0051247 Not Cancer Driver No 42 0.258 34 11 0.324 1
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0051247 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0051247 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0051247 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0051247 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0051247 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0051247 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0051247 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0051247 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0051247 Not Cancer Driver No 55 0.118 165 23 0.139 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0051247 Not Cancer Driver No 49 0.153 84 12 0.143 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0051247 Not Cancer Driver No 112 0.169 553 98 0.177 1
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0051247 Not Cancer Driver No 33 0.118 169 26 0.154 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0051247 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0051247 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0051247 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0051247 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0051247 Not Cancer Driver No 52 0.149 85 12 0.141 0
INS INS P01308 Insulin chr11 GO:0051247 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0051247 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0051247 Compendium Yes 71 0.1 337 39 0.116 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0051247 Not Cancer Driver No 9 0.05 45 1 0.022 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0051247 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0051247 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0051247 Not Cancer Driver No 26 0.13 58 11 0.19 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0051247 Census, Compendium Yes 136 0.12 59 5 0.085 5
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0051247 Not Cancer Driver No 190 0.152 724 113 0.156 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0051247 Not Cancer Driver No 16 0.098 142 13 0.092 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0051247 Not Cancer Driver No 67 0.145 19 5 0.263 0
KANSL1_ENST00000262419 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 GO:0051247 Not Cancer Driver No 168 0.152 876 130 0.148 0
KANSL2 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 GO:0051247 Not Cancer Driver No 53 0.108 304 27 0.089 0
KANSL3 KANSL3 Q9P2N6 KAT8 regulatory NSL complex subunit 3 chr2 GO:0051247 Not Cancer Driver No 92 0.102 547 62 0.113 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0051247 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0051247 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0051247 Census Yes 97 0.159 327 47 0.144 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:0051247 Not Cancer Driver No 66 0.144 156 20 0.128 4
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0051247 Not Cancer Driver No 67 0.079 291 28 0.096 3
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0051247 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLHL40 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 GO:0051247 Not Cancer Driver No 108 0.174 44 8 0.182 13
KLKB1 KLKB1 P03952 Plasma kallikrein chr4 GO:0051247 Not Cancer Driver No 117 0.183 24 1 0.042 3
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0051247 Census, Compendium Yes 446 0.112 3145 338 0.107 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0051247 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KPNA7 KPNA7 A9QM74 Importin subunit alpha-8 chr7 GO:0051247 Not Cancer Driver No 36 0.07 66 2 0.03 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0051247 Not Cancer Driver No 46 0.176 16 6 0.375 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0051247 Census, Compendium Yes 161 0.142 788 100 0.127 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0051247 Compendium Yes 56 0.136 177 29 0.164 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0051247 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0051247 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0051247 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEP LEP P41159 Leptin chr7 GO:0051247 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0051247 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0051247 Not Cancer Driver No 57 0.132 112 19 0.17 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0051247 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA2 LILRA2 Q8N149 Leukocyte immunoglobulin-like receptor subfamily A member 2 chr19 GO:0051247 Not Cancer Driver No 163 0.337 137 44 0.321 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0051247 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0051247 Not Cancer Driver No 148 0.248 235 50 0.213 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0051247 Not Cancer Driver No 37 0.177 86 12 0.14 0
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0051247 Census Yes 68 0.102 544 49 0.09 131
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0051247 Not Cancer Driver No 54 0.111 1 0 0.0 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0051247 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0051247 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0051247 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0051247 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRRTM3 LRRTM3 Q86VH5 Leucine-rich repeat transmembrane neuronal protein 3 chr10 GO:0051247 Not Cancer Driver No 142 0.244 136 31 0.228 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0051247 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0051247 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGEC2 MAGEC2 Q9UBF1 Melanoma-associated antigen C2 chrX GO:0051247 Not Cancer Driver No 170 0.456 129 69 0.535 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0051247 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0051247 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0051247 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0051247 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0051247 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0051247 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0051247 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0051247 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0051247 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0051247 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0051247 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0051247 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0051247 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0051247 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0051247 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0051247 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0051247 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0051247 Not Cancer Driver No 70 0.134 173 25 0.145 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0051247 Not Cancer Driver No 37 0.132 120 16 0.133 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0051247 Not Cancer Driver No 33 0.134 23 5 0.217 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0051247 Not Cancer Driver No 85 0.121 550 68 0.124 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0051247 Not Cancer Driver No 47 0.145 5 2 0.4 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0051247 Not Cancer Driver No 90 0.102 389 44 0.113 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0051247 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 GO:0051247 Not Cancer Driver No 72 0.156 151 18 0.119 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0051247 Not Cancer Driver No 75 0.154 483 74 0.153 46
MELTF MELTF P08582 Melanotransferrin chr3 GO:0051247 Not Cancer Driver No 106 0.144 23 6 0.261 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0051247 Not Cancer Driver No 74 0.128 274 29 0.106 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0051247 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0051247 Not Cancer Driver No 45 0.108 145 16 0.11 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0051247 Not Cancer Driver No 64 0.11 118 11 0.093 1
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0051247 Not Cancer Driver No 23 0.074 64 2 0.031 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:0051247 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0051247 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0051247 Not Cancer Driver No 46 0.111 51 7 0.137 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0051247 Not Cancer Driver No 68 0.181 64 11 0.172 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0051247 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:0051247 Not Cancer Driver No 92 0.129 327 42 0.128 0
MTCP1_ENST00000362018 MTCP1 P56278 Protein p13 MTCP-1 chrX GO:0051247 Census, Compendium Yes 14 0.131 6 0 0.0 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 GO:0051247 Not Cancer Driver No 70 0.118 225 28 0.124 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0051247 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0051247 Not Cancer Driver No 11 0.093 11 3 0.273 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0051247 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0051247 Not Cancer Driver No 48 0.136 16 2 0.125 0
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0051247 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0051247 Census Yes 82 0.128 528 69 0.131 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0051247 Not Cancer Driver No 608 0.13 1398 189 0.135 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0051247 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0051247 Census Yes 67 0.128 395 51 0.129 0
NAP1L2 NAP1L2 Q9ULW6 Nucleosome assembly protein 1-like 2 chrX GO:0051247 Not Cancer Driver No 124 0.27 178 55 0.309 0
NBN NBN O60934 Nibrin chr8 GO:0051247 Census Yes 90 0.119 417 54 0.129 1
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0051247 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0051247 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0051247 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0051247 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0051247 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0051247 Not Cancer Driver No 27 0.08 198 13 0.066 0
NDN NDN Q99608 Necdin chr15 GO:0051247 Not Cancer Driver No 123 0.383 117 42 0.359 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0051247 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0051247 Not Cancer Driver No 213 0.182 281 60 0.214 0
NELFA_ENST00000411638 NELFA Q9H3P2 Negative elongation factor A chr4 GO:0051247 Not Cancer Driver No 68 0.129 373 58 0.155 0
NELFE NELFE P18615 Negative elongation factor E chr6 GO:0051247 Not Cancer Driver No 47 0.124 352 45 0.128 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0051247 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0051247 Census, Compendium Yes 228 0.377 402 62 0.154 4
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0051247 Not Cancer Driver No 66 0.274 93 25 0.269 1
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0051247 Not Cancer Driver No 26 0.089 215 21 0.098 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 GO:0051247 Not Cancer Driver No 66 0.167 18 3 0.167 22
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0051247 Compendium Yes 353 0.126 1528 184 0.12 37
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0051247 Not Cancer Driver No 64 0.142 451 64 0.142 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0051247 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0051247 Not Cancer Driver No 106 0.119 203 28 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0051247 Not Cancer Driver No 34 0.111 104 12 0.115 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0051247 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0051247 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0051247 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0051247 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0051247 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0051247 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0051247 Not Cancer Driver No 123 0.213 0 0 0.0 0
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0051247 Not Cancer Driver No 162 0.141 253 34 0.134 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0051247 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0051247 Not Cancer Driver No 227 0.315 425 134 0.315 0
NSD3 NSD3 Q9BZ95 Histone-lysine N-methyltransferase NSD3 chr8 GO:0051247 Census Yes 164 0.114 679 98 0.144 0
NSMCE3 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:0051247 Not Cancer Driver No 33 0.109 128 7 0.055 2
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0051247 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0051247 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0051247 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0051247 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0051247 Census, Compendium Yes 249 0.297 57 21 0.368 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0051247 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0051247 Not Cancer Driver No 91 0.245 30 3 0.1 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0051247 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0051247 Not Cancer Driver No 43 0.171 114 24 0.211 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0051247 Census, Compendium Yes 100 0.157 317 55 0.174 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0051247 Not Cancer Driver No 52 0.123 290 31 0.107 0
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0051247 Not Cancer Driver No 23 0.128 3 0 0.0 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0051247 Not Cancer Driver No 77 0.145 378 56 0.148 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0051247 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0051247 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0051247 Compendium Yes 89 0.17 242 49 0.202 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0051247 Not Cancer Driver No 11 0.058 30 0 0.0 5
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0051247 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAXBP1 PAXBP1 Q9Y5B6 PAX3- and PAX7-binding protein 1 chr21 GO:0051247 Not Cancer Driver No 96 0.105 532 55 0.103 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0051247 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0051247 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0051247 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0051247 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0051247 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0051247 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0051247 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0051247 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0051247 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0051247 Not Cancer Driver No 33 0.059 121 12 0.099 0
PEF1 PEF1 Q9UBV8 Peflin chr1 GO:0051247 Not Cancer Driver No 44 0.155 122 20 0.164 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0051247 Not Cancer Driver No 47 0.112 167 17 0.102 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0051247 Not Cancer Driver No 28 0.145 0 0 0.0 1
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0051247 Not Cancer Driver No 20 0.143 0 0 0.0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0051247 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0051247 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 GO:0051247 Not Cancer Driver No 62 0.109 277 29 0.105 0
PHF19_ENST00000373896 PHF19 Q5T6S3 PHD finger protein 19 chr9 GO:0051247 Not Cancer Driver No 66 0.114 129 19 0.147 0
PHF20 PHF20 Q9BVI0 PHD finger protein 20 chr20 GO:0051247 Not Cancer Driver No 130 0.128 667 82 0.123 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 GO:0051247 Not Cancer Driver No 45 0.112 331 37 0.112 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 GO:0051247 Not Cancer Driver No 80 0.123 241 43 0.178 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0051247 Not Cancer Driver No 70 0.111 266 31 0.117 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0051247 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0051247 Not Cancer Driver No 83 0.11 419 45 0.107 2
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0051247 Census Yes 89 0.137 320 42 0.131 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0051247 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0051247 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0051247 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0051247 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0051247 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0051247 Not Cancer Driver No 138 0.142 232 38 0.164 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0051247 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0051247 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0051247 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0051247 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0051247 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 GO:0051247 Not Cancer Driver No 17 0.116 0 0 0.0 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0051247 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0051247 Not Cancer Driver No 75 0.116 202 15 0.074 0
PML PML P29590 Protein PML chr15 GO:0051247 Census, Compendium Yes 112 0.127 312 34 0.109 0
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 GO:0051247 Not Cancer Driver No 75 0.1 55 5 0.091 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 GO:0051247 Not Cancer Driver No 84 0.112 60 3 0.05 15
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0051247 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0051247 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0051247 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0051247 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0051247 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0051247 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0051247 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0051247 Not Cancer Driver No 132 0.233 220 66 0.3 0
PPP1R7 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 GO:0051247 Not Cancer Driver No 46 0.128 78 16 0.205 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0051247 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 GO:0051247 Not Cancer Driver No 64 0.106 178 13 0.073 4
PRDM12 PRDM12 Q9H4Q4 PR domain zinc finger protein 12 chr9 GO:0051247 Not Cancer Driver No 26 0.071 82 1 0.012 6
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0051247 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRICKLE1_ENST00000640055 PRICKLE1 Q96MT3 Prickle-like protein 1 chr12 GO:0051247 Not Cancer Driver No 146 0.176 485 91 0.188 3
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0051247 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0051247 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0051247 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0051247 Compendium Yes 79 0.117 43 9 0.209 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0051247 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0051247 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0051247 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0051247 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRLR PRLR P16471 Prolactin receptor chr5 GO:0051247 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0051247 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRNP PRNP P04156 Major prion protein chr20 GO:0051247 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0051247 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0051247 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0051247 Not Cancer Driver No 42 0.094 235 24 0.102 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0051247 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0051247 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0051247 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0051247 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0051247 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0051247 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0051247 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0051247 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0051247 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0051247 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0051247 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0051247 Not Cancer Driver No 23 0.128 30 9 0.3 0
PXYLP1 PXYLP1 Q8TE99 2-phosphoxylose phosphatase 1 chr3 GO:0051247 Not Cancer Driver No 63 0.131 32 13 0.406 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0051247 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0051247 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 GO:0051247 Not Cancer Driver No 24 0.119 40 3 0.075 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0051247 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0051247 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0051247 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0051247 Census, Compendium Yes 89 0.137 169 38 0.225 22
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0051247 Not Cancer Driver No 16 0.108 0 0 0.0 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0051247 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0051247 Not Cancer Driver No 73 0.1 413 30 0.073 0
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0051247 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0051247 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0051247 Not Cancer Driver No 32 0.175 8 2 0.25 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0051247 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0051247 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASD2 RASD2 Q96D21 GTP-binding protein Rhes chr22 GO:0051247 Not Cancer Driver No 59 0.222 14 2 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0051247 Not Cancer Driver No 96 0.12 191 12 0.063 1
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0051247 Not Cancer Driver No 90 0.276 126 44 0.349 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 GO:0051247 Not Cancer Driver No 37 0.089 183 11 0.06 0
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0051247 Not Cancer Driver No 23 0.117 87 11 0.126 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0051247 Not Cancer Driver No 10 0.093 18 1 0.056 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0051247 Not Cancer Driver No 19 0.041 87 7 0.08 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0051247 Not Cancer Driver No 33 0.126 23 0 0.0 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0051247 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:0051247 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0051247 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0051247 Not Cancer Driver No 73 0.23 28 5 0.179 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0051247 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0051247 Not Cancer Driver No 63 0.14 105 13 0.124 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0051247 Not Cancer Driver No 38 0.121 69 9 0.13 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0051247 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0051247 Not Cancer Driver No 63 0.117 143 20 0.14 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:0051247 Not Cancer Driver No 46 0.102 83 11 0.133 1
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0051247 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0051247 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 GO:0051247 Not Cancer Driver No 80 0.135 190 26 0.137 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0051247 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0051247 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0051247 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0051247 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0051247 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0051247 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0051247 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 GO:0051247 Not Cancer Driver No 34 0.116 85 14 0.165 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0051247 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0051247 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0051247 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0051247 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0051247 Not Cancer Driver No 176 0.132 241 21 0.087 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0051247 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0051247 Not Cancer Driver No 54 0.143 97 15 0.155 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0051247 Not Cancer Driver No 66 0.145 270 44 0.163 0
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 GO:0051247 Not Cancer Driver No 83 0.117 568 67 0.118 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0051247 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD3 RWDD3 Q9Y3V2 RWD domain-containing protein 3 chr1 GO:0051247 Not Cancer Driver No 40 0.15 12 4 0.333 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0051247 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0051247 Not Cancer Driver No 38 0.108 16 3 0.188 2
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:0051247 Not Cancer Driver No 39 0.113 90 6 0.067 0
SAP30BP SAP30BP Q9UHR5 SAP30-binding protein chr17 GO:0051247 Not Cancer Driver No 25 0.081 233 19 0.082 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0051247 Not Cancer Driver No 101 0.105 404 45 0.111 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0051247 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0051247 Not Cancer Driver No 39 0.131 17 2 0.118 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0051247 Not Cancer Driver No 81 0.262 4 0 0.0 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0051247 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0051247 Not Cancer Driver No 147 0.253 561 145 0.258 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0051247 Not Cancer Driver No 73 0.124 285 38 0.133 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0051247 Not Cancer Driver No 61 0.128 220 31 0.141 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0051247 Not Cancer Driver No 47 0.159 1 0 0.0 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0051247 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0051247 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0051247 Not Cancer Driver No 110 0.128 440 72 0.164 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0051247 Not Cancer Driver No 86 0.109 526 52 0.099 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0051247 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0051247 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0051247 Not Cancer Driver No 33 0.093 164 12 0.073 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0051247 Not Cancer Driver No 19 0.117 95 17 0.179 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0051247 Not Cancer Driver No 52 0.123 52 6 0.115 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0051247 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC25A37 SLC25A37 Q9NYZ2 Mitoferrin-1 chr8 GO:0051247 Not Cancer Driver No 45 0.133 68 5 0.074 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0051247 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0051247 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0051247 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0051247 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0051247 Not Cancer Driver No 102 0.144 65 12 0.185 1
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0051247 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0051247 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0051247 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0051247 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0051247 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0051247 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0051247 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0051247 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0051247 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0051247 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0051247 Not Cancer Driver No 71 0.119 231 23 0.1 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:0051247 Not Cancer Driver No 73 0.133 49 4 0.082 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0051247 Not Cancer Driver No 28 0.059 400 24 0.06 4
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0051247 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0051247 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0051247 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0051247 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0051247 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPON1 SPON1 Q9HCB6 Spondin-1 chr11 GO:0051247 Not Cancer Driver No 120 0.149 191 30 0.157 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0051247 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0051247 Not Cancer Driver No 73 0.149 252 38 0.151 1
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0051247 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 GO:0051247 Not Cancer Driver No 42 0.154 75 3 0.04 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0051247 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0051247 Not Cancer Driver No 127 0.111 528 64 0.121 4
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0051247 Not Cancer Driver No 330 0.315 820 282 0.344 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0051247 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0051247 Census, Compendium Yes 110 0.143 152 15 0.099 19
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0051247 Not Cancer Driver No 70 0.144 231 30 0.13 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0051247 Not Cancer Driver No 121 0.122 659 83 0.126 2
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0051247 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0051247 Not Cancer Driver No 59 0.143 15 1 0.067 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0051247 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0051247 Census Yes 96 0.151 131 27 0.206 5
SYMPK SYMPK Q92797 Symplekin chr19 GO:0051247 Not Cancer Driver No 156 0.122 398 42 0.106 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0051247 Not Cancer Driver No 93 0.149 285 39 0.137 0
TADA2B TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 GO:0051247 Not Cancer Driver No 55 0.131 128 19 0.148 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0051247 Census Yes 54 0.163 305 53 0.174 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0051247 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0051247 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0051247 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0051247 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0051247 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0051247 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0051247 Not Cancer Driver No 101 0.139 42 5 0.119 12
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0051247 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0051247 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0051247 Census Yes 30 0.263 5 1 0.2 0
TCL1B TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 GO:0051247 Not Cancer Driver No 38 0.297 11 1 0.091 0
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0051247 Not Cancer Driver No 728 0.267 482 164 0.34 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0051247 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0051247 Not Cancer Driver No 28 0.07 310 16 0.052 0
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0051247 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0051247 Compendium Yes 61 0.18 285 52 0.182 0
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0051247 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0051247 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0051247 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0051247 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0051247 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0051247 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0051247 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0051247 Census, Compendium Yes 106 0.187 60 16 0.267 25
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0051247 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0051247 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0051247 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0051247 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0051247 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0051247 Not Cancer Driver No 40 0.065 188 9 0.048 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0051247 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0051247 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0051247 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0051247 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0051247 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0051247 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0051247 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0051247 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0051247 Not Cancer Driver No 21 0.382 55 21 0.382 0
TNP2 TNP2 Q05952 Nuclear transition protein 2 chr16 GO:0051247 Not Cancer Driver No 23 0.167 138 23 0.167 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0051247 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0051247 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0051247 Not Cancer Driver No 51 0.107 268 29 0.108 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0051247 Not Cancer Driver No 149 0.143 795 105 0.132 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0051247 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRABD2A TRABD2A Q86V40 Metalloprotease TIKI1 chr2 GO:0051247 Not Cancer Driver No 80 0.158 132 35 0.265 0
TRABD2B TRABD2B A6NFA1 Metalloprotease TIKI2 chr1 GO:0051247 Not Cancer Driver No 3 0.006 211 1 0.005 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0051247 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0051247 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0051247 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0051247 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0051247 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0051247 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0051247 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0051247 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 GO:0051247 Not Cancer Driver No 92 0.221 257 61 0.237 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0051247 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0051247 Not Cancer Driver No 136 0.159 352 46 0.131 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0051247 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXN TXN P10599 Thioredoxin chr9 GO:0051247 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:0051247 Not Cancer Driver No 84 0.131 219 33 0.151 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0051247 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0051247 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0051247 Not Cancer Driver No 13 0.088 14 0 0.0 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0051247 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0051247 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0051247 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0051247 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2V1_ENST00000371674 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 GO:0051247 Not Cancer Driver No 19 0.129 51 5 0.098 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0051247 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0051247 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0051247 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0051247 Not Cancer Driver No 82 0.131 581 79 0.136 8
UCN UCN P55089 Urocortin chr2 GO:0051247 Not Cancer Driver No 7 0.056 61 4 0.066 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0051247 Not Cancer Driver No 20 0.083 89 4 0.045 1
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0051247 Not Cancer Driver No 10 0.079 41 1 0.024 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0051247 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0051247 Not Cancer Driver No 98 0.119 394 42 0.107 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0051247 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0051247 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0051247 Not Cancer Driver No 128 0.305 37 12 0.324 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0051247 Not Cancer Driver No 65 0.137 180 18 0.1 0
WBP1L_ENST00000369889 WBP1L Q9NX94 WW domain binding protein 1-like chr10 GO:0051247 Not Cancer Driver No 27 0.079 225 21 0.093 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0051247 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0051247 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:0051247 Not Cancer Driver No 30 0.09 35 3 0.086 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 GO:0051247 Not Cancer Driver No 25 0.082 7 1 0.143 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0051247 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0051247 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0051247 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0051247 Not Cancer Driver No 66 0.174 0 0 0.0 2
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0051247 Not Cancer Driver No 89 0.179 55 6 0.109 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0051247 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0051247 Not Cancer Driver No 49 0.132 359 47 0.131 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0051247 Not Cancer Driver No 67 0.116 376 44 0.117 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0051247 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0051247 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:0051247 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0051247 Not Cancer Driver No 85 0.149 383 55 0.144 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0051247 Not Cancer Driver No 126 0.191 54 12 0.222 0