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Total number of protein in "GO:0048878" GO term:  528

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0048878 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0048878 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0048878 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0048878 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0048878 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCC6 ABCC6 O95255 ATP-binding cassette sub-family C member 6 chr16 GO:0048878 Not Cancer Driver No 193 0.128 133 20 0.15 87
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0048878 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0048878 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0048878 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0048878 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0048878 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACER1 ACER1 Q8TDN7 Alkaline ceramidase 1 chr19 GO:0048878 Not Cancer Driver No 54 0.205 0 0 0.0 0
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0048878 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0048878 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0048878 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0048878 Not Cancer Driver No 255 0.189 53 11 0.208 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0048878 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0048878 Not Cancer Driver No 64 0.196 12 4 0.333 0
AGT AGT P01019 Angiotensinogen chr1 GO:0048878 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0048878 Not Cancer Driver No 95 0.265 0 0 0.0 1
AKAP11 AKAP11 Q9UKA4 A-kinase anchor protein 11 chr13 GO:0048878 Not Cancer Driver No 196 0.103 922 91 0.099 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0048878 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0048878 Not Cancer Driver No 52 0.165 19 1 0.053 0
ALAS2 ALAS2 P22557 5-aminolevulinate synthase, erythroid-specific, mitochondrial chrX GO:0048878 Not Cancer Driver No 107 0.182 87 17 0.195 24
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0048878 Not Cancer Driver No 73 0.11 73 12 0.164 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0048878 Not Cancer Driver No 101 0.144 16 3 0.188 18
ALOXE3_ENST00000448843 ALOXE3 Q9BYJ1 Hydroperoxide isomerase ALOXE3 chr17 GO:0048878 Not Cancer Driver No 108 0.152 69 13 0.188 6
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0048878 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0048878 Not Cancer Driver No 860 0.196 3054 579 0.19 0
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0048878 Not Cancer Driver No 138 0.12 404 59 0.146 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0048878 Not Cancer Driver No 96 0.253 29 8 0.276 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0048878 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0048878 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0048878 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0048878 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0048878 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0048878 Not Cancer Driver No 23 0.085 0 0 0.0 0
AQP2 AQP2 P41181 Aquaporin-2 chr12 GO:0048878 Not Cancer Driver No 52 0.192 31 3 0.097 28
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0048878 Not Cancer Driver No 34 0.116 12 0 0.0 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0048878 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0048878 Not Cancer Driver No 75 0.254 12 0 0.0 0
ATP12A_ENST00000381946 ATP12A P54707 Potassium-transporting ATPase alpha chain 2 chr13 GO:0048878 Not Cancer Driver No 203 0.195 117 24 0.205 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0048878 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0048878 Census Yes 115 0.112 115 16 0.139 6
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0048878 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0048878 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP1A4 ATP1A4 Q13733 Sodium/potassium-transporting ATPase subunit alpha-4 chr1 GO:0048878 Not Cancer Driver No 195 0.19 117 24 0.205 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0048878 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0048878 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 GO:0048878 Not Cancer Driver No 36 0.129 6 1 0.167 0
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0048878 Not Cancer Driver No 157 0.157 80 11 0.138 1
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0048878 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0048878 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0048878 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP2B3_ENST00000349466 ATP2B3 Q16720 Plasma membrane calcium-transporting ATPase 3 chrX GO:0048878 Census Yes 245 0.201 328 74 0.226 2
ATP2C1_ENST00000508532 ATP2C1 P98194 Calcium-transporting ATPase type 2C member 1 chr3 GO:0048878 Not Cancer Driver No 125 0.136 44 5 0.114 20
ATP4A ATP4A P20648 Potassium-transporting ATPase alpha chain 1 chr19 GO:0048878 Not Cancer Driver No 201 0.194 121 30 0.248 0
ATP4B ATP4B P51164 Potassium-transporting ATPase subunit beta chr13 GO:0048878 Not Cancer Driver No 35 0.12 2 0 0.0 0
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0048878 Not Cancer Driver No 56 0.16 0 0 0.0 2
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 GO:0048878 Not Cancer Driver No 77 0.15 66 14 0.212 9
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0048878 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0048878 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0048878 Not Cancer Driver No 83 0.196 51 5 0.098 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0048878 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0048878 Census Yes 30 0.156 39 2 0.051 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0048878 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0048878 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDKRB1_ENST00000611804 BDKRB1 P46663 B1 bradykinin receptor chr14 GO:0048878 Not Cancer Driver No 68 0.193 3 0 0.0 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0048878 Not Cancer Driver No 95 0.185 226 51 0.226 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0048878 Not Cancer Driver No 7 0.033 0 0 0.0 0
BPIFA1_ENST00000375413 BPIFA1 Q9NP55 BPI fold-containing family A member 1 chr20 GO:0048878 Not Cancer Driver No 54 0.211 0 0 0.0 0
BTBD9 BTBD9 Q96Q07 BTB/POZ domain-containing protein 9 chr6 GO:0048878 Not Cancer Driver No 84 0.137 66 6 0.091 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0048878 Not Cancer Driver No 42 0.171 73 14 0.192 0
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0048878 Not Cancer Driver No 88 0.183 72 16 0.222 0
CA12 CA12 O43570 Carbonic anhydrase 12 chr15 GO:0048878 Not Cancer Driver No 41 0.116 40 7 0.175 2
CA2 CA2 P00918 Carbonic anhydrase 2 chr8 GO:0048878 Not Cancer Driver No 41 0.158 55 8 0.145 4
CA7 CA7 P43166 Carbonic anhydrase 7 chr16 GO:0048878 Not Cancer Driver No 22 0.083 65 5 0.077 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0048878 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 GO:0048878 Not Cancer Driver No 416 0.178 917 115 0.125 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0048878 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0048878 Census, Compendium Yes 342 0.158 736 126 0.171 2
CACNA1E_ENST00000621551 CACNA1E Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E chr1 GO:0048878 Not Cancer Driver No 778 0.336 917 339 0.37 14
CACNA1F CACNA1F O60840 Voltage-dependent L-type calcium channel subunit alpha-1F chrX GO:0048878 Not Cancer Driver No 284 0.144 530 78 0.147 20
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0048878 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0048878 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0048878 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0048878 Not Cancer Driver No 155 0.235 478 106 0.222 0
CALB1 CALB1 P05937 Calbindin chr8 GO:0048878 Not Cancer Driver No 46 0.176 0 0 0.0 0
CALB2 CALB2 P22676 Calretinin chr16 GO:0048878 Not Cancer Driver No 54 0.199 39 8 0.205 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0048878 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0048878 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0048878 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0048878 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0048878 Not Cancer Driver No 57 0.114 84 10 0.119 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0048878 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0048878 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASQ1 CASQ1 P31415 Calsequestrin-1 chr1 GO:0048878 Not Cancer Driver No 77 0.194 110 18 0.164 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0048878 Not Cancer Driver No 304 0.282 189 60 0.317 108
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0048878 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0048878 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCDC115 CCDC115 Q96NT0 Coiled-coil domain-containing protein 115 chr2 GO:0048878 Not Cancer Driver No 21 0.117 89 8 0.09 2
CCDC47_ENST00000403162 CCDC47 Q96A33 PAT complex subunit CCDC47 chr17 GO:0048878 Not Cancer Driver No 49 0.101 265 23 0.087 0
CCR5 CCR5 P51681 C-C chemokine receptor type 5 chr3 GO:0048878 Not Cancer Driver No 107 0.304 0 0 0.0 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0048878 Not Cancer Driver No 80 0.144 312 46 0.147 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0048878 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0048878 Not Cancer Driver No 207 0.152 105 10 0.095 0
CETP CETP P11597 Cholesteryl ester transfer protein chr16 GO:0048878 Not Cancer Driver No 58 0.118 0 0 0.0 3
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0048878 Not Cancer Driver No 287 0.194 145 18 0.124 151
CIAO3 CIAO3 Q9H6Q4 Cytosolic iron-sulfur assembly component 3 chr16 GO:0048878 Not Cancer Driver No 49 0.103 68 4 0.059 0
CKB CKB P12277 Creatine kinase B-type chr14 GO:0048878 Not Cancer Driver No 31 0.081 102 4 0.039 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0048878 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0048878 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0048878 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0048878 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLN5_ENST00000377453 CLN5 O75503 Ceroid-lipofuscinosis neuronal protein 5 chr13 GO:0048878 Not Cancer Driver No 39 0.109 16 1 0.062 12
CLN6 CLN6 Q9NWW5 Ceroid-lipofuscinosis neuronal protein 6 chr15 GO:0048878 Not Cancer Driver No 28 0.09 13 0 0.0 24
CMA1 CMA1 P23946 Chymase chr14 GO:0048878 Not Cancer Driver No 47 0.19 9 1 0.111 0
CNNM1 CNNM1 Q9NRU3 Metal transporter CNNM1 chr10 GO:0048878 Not Cancer Driver No 127 0.134 318 39 0.123 0
CNNM2 CNNM2 Q9H8M5 Metal transporter CNNM2 chr10 GO:0048878 Not Cancer Driver No 116 0.133 195 22 0.113 5
CNNM3 CNNM3 Q8NE01 Metal transporter CNNM3 chr2 GO:0048878 Not Cancer Driver No 47 0.066 101 7 0.069 0
CNNM4 CNNM4 Q6P4Q7 Metal transporter CNNM4 chr2 GO:0048878 Not Cancer Driver No 104 0.134 116 22 0.19 4
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0048878 Not Cancer Driver No 129 0.273 9 1 0.111 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0048878 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0048878 Not Cancer Driver No 368 0.245 73 22 0.301 140
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0048878 Not Cancer Driver No 45 0.134 4 0 0.0 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0048878 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0048878 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL11 CXCL11 O14625 C-X-C motif chemokine 11 chr4 GO:0048878 Not Cancer Driver No 13 0.138 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0048878 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXorf21 TASL Q9HAI6 TLR adapter interacting with SLC15A4 on the lysosome chrX GO:0048878 Not Cancer Driver No 73 0.243 66 21 0.318 0
CYB561D2_ENST00000232508 CYB561D2 O14569 Transmembrane reductase CYB561D2 chr3 GO:0048878 Not Cancer Driver No 9 0.041 0 0 0.0 0
CYB561_ENST00000392976 CYB561 P49447 Transmembrane ascorbate-dependent reductase CYB561 chr17 GO:0048878 Not Cancer Driver No 28 0.112 6 0 0.0 1
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0048878 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBRD1 CYBRD1 Q53TN4 Plasma membrane ascorbate-dependent reductase CYBRD1 chr2 GO:0048878 Not Cancer Driver No 34 0.119 59 10 0.169 0
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0048878 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0048878 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP4A11 CYP4A11 Q02928 Cytochrome P450 4A11 chr1 GO:0048878 Not Cancer Driver No 131 0.252 24 8 0.333 0
CYP4F12_ENST00000324632 CYP4F12 Q9HCS2 Cytochrome P450 4F12 chr19 GO:0048878 Not Cancer Driver No 138 0.263 18 4 0.222 0
CYP4F2 CYP4F2 P78329 Cytochrome P450 4F2 chr19 GO:0048878 Not Cancer Driver No 136 0.262 17 3 0.176 0
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0048878 Not Cancer Driver No 109 0.216 48 8 0.167 0
DCN DCN P07585 Decorin chr12 GO:0048878 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0048878 Not Cancer Driver No 126 0.111 50 8 0.16 4
DGAT1 DGAT1 O75907 Diacylglycerol O-acyltransferase 1 chr8 GO:0048878 Not Cancer Driver No 52 0.107 62 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0048878 Not Cancer Driver No 56 0.144 17 2 0.118 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0048878 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0048878 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0048878 Not Cancer Driver No 88 0.22 45 17 0.378 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0048878 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0048878 Not Cancer Driver No 69 0.29 140 44 0.314 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0048878 Not Cancer Driver No 62 0.145 21 6 0.286 2
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0048878 Not Cancer Driver No 35 0.082 206 8 0.039 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0048878 Not Cancer Driver No 20 0.131 28 4 0.143 0
ELOVL1_ENST00000372458 ELOVL1 Q9BW60 Elongation of very long chain fatty acids protein 1 chr1 GO:0048878 Not Cancer Driver No 32 0.115 0 0 0.0 1
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0048878 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0048878 Not Cancer Driver No 148 0.16 101 5 0.05 33
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0048878 Not Cancer Driver No 102 0.223 65 19 0.292 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0048878 Census, Compendium Yes 120 0.138 449 53 0.118 6
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0048878 Not Cancer Driver No 125 0.128 250 28 0.112 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0048878 Census Yes 107 0.143 58 7 0.121 12
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0048878 Census, Compendium Yes 93 0.13 12 1 0.083 9
F2 F2 P00734 Prothrombin chr11 GO:0048878 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0048878 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0048878 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0048878 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0048878 Not Cancer Driver No 43 0.112 46 4 0.087 0
FA2H FA2H Q7L5A8 Fatty acid 2-hydroxylase chr16 GO:0048878 Not Cancer Driver No 33 0.089 73 0 0.0 3
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0048878 Not Cancer Driver No 22 0.165 3 0 0.0 0
FAM155A NALF1 B1AL88 NALCN channel auxiliary factor 1 chr13 GO:0048878 Not Cancer Driver No 121 0.264 162 51 0.315 0
FAM155B NALF2 O75949 NALCN channel auxiliary factor 2 chrX GO:0048878 Not Cancer Driver No 56 0.119 160 26 0.163 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0048878 Not Cancer Driver No 65 0.231 94 18 0.191 1
FATE1 FATE1 Q969F0 Fetal and adult testis-expressed transcript protein chrX GO:0048878 Not Cancer Driver No 45 0.246 117 30 0.256 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0048878 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0048878 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0048878 Census, Compendium Yes 113 0.141 162 28 0.173 0
FHL1_ENST00000345434 FHL1 Q13642 Four and a half LIM domains protein 1 chrX GO:0048878 Not Cancer Driver No 56 0.173 51 7 0.137 13
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0048878 Not Cancer Driver No 25 0.164 6 0 0.0 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0048878 Not Cancer Driver No 28 0.107 0 0 0.0 1
FLG FLG P20930 Filaggrin chr1 GO:0048878 Not Cancer Driver No 1612 0.397 3956 1593 0.403 0
FLG2 FLG2 Q5D862 Filaggrin-2 chr1 GO:0048878 Not Cancer Driver No 613 0.256 2252 577 0.256 0
FOXA3 FOXA3 P55318 Hepatocyte nuclear factor 3-gamma chr19 GO:0048878 Not Cancer Driver No 62 0.177 232 40 0.172 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0048878 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0048878 Not Cancer Driver No 79 0.12 548 64 0.117 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0048878 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0048878 Census, Compendium Yes 70 0.104 595 68 0.114 0
FUNDC2 FUNDC2 Q9BWH2 FUN14 domain-containing protein 2 chrX GO:0048878 Not Cancer Driver No 28 0.148 34 3 0.088 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0048878 Not Cancer Driver No 55 0.093 61 0 0.0 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0048878 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0048878 Not Cancer Driver No 48 0.109 301 34 0.113 18
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0048878 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0048878 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0048878 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0048878 Not Cancer Driver No 32 0.117 31 3 0.097 0
GCM2 GCM2 O75603 Chorion-specific transcription factor GCMb chr6 GO:0048878 Not Cancer Driver No 91 0.18 272 50 0.184 7
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0048878 Not Cancer Driver No 41 0.097 3 0 0.0 5
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0048878 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0048878 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0048878 Not Cancer Driver No 42 0.161 12 4 0.333 4
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 GO:0048878 Not Cancer Driver No 71 0.106 187 9 0.048 3
GNA15 GNA15 P30679 Guanine nucleotide-binding protein subunit alpha-15 chr19 GO:0048878 Not Cancer Driver No 51 0.136 15 6 0.4 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0048878 Not Cancer Driver No 56 0.136 35 5 0.143 0
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0048878 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0048878 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0048878 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR157 GPR157 Q5UAW9 G-protein coupled receptor 157 chr1 GO:0048878 Not Cancer Driver No 37 0.11 38 6 0.158 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:0048878 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:0048878 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0048878 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:0048878 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0048878 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0048878 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:0048878 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0048878 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0048878 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRHL1 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 GO:0048878 Not Cancer Driver No 99 0.16 256 36 0.141 0
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 GO:0048878 Not Cancer Driver No 83 0.133 291 38 0.131 3
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0048878 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0048878 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0048878 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRINA_ENST00000395068 GRINA Q7Z429 Protein lifeguard 1 chr8 GO:0048878 Not Cancer Driver No 39 0.105 150 15 0.1 0
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0048878 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0048878 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0048878 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0048878 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0048878 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTO1 GSTO1 P78417 Glutathione S-transferase omega-1 chr10 GO:0048878 Not Cancer Driver No 26 0.108 18 1 0.056 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 GO:0048878 Not Cancer Driver No 28 0.077 10 0 0.0 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0048878 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0048878 Not Cancer Driver No 97 0.145 454 60 0.132 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0048878 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0048878 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0048878 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0048878 Not Cancer Driver No 187 0.155 631 58 0.092 3
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0048878 Census Yes 38 0.097 248 17 0.069 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0048878 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0048878 Census Yes 118 0.143 435 51 0.117 0
HK1_ENST00000359426 HK1 P19367 Hexokinase-1 chr10 GO:0048878 Not Cancer Driver No 127 0.138 75 16 0.213 6
HK2 HK2 P52789 Hexokinase-2 chr2 GO:0048878 Not Cancer Driver No 138 0.15 77 7 0.091 0
HK3 HK3 P52790 Hexokinase-3 chr5 GO:0048878 Not Cancer Driver No 164 0.178 71 17 0.239 0
HKDC1 HKDC1 Q2TB90 Hexokinase HKDC1 chr10 GO:0048878 Not Cancer Driver No 146 0.159 33 3 0.091 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 GO:0048878 Not Cancer Driver No 135 0.285 127 48 0.378 5
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 GO:0048878 Not Cancer Driver No 46 0.13 243 32 0.132 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:0048878 Not Cancer Driver No 53 0.15 233 32 0.137 1
HRNR HRNR Q86YZ3 Hornerin chr1 GO:0048878 Not Cancer Driver No 612 0.215 2767 601 0.217 0
HSH2D HSH2D Q96JZ2 Hematopoietic SH2 domain-containing protein chr19 GO:0048878 Not Cancer Driver No 44 0.125 233 38 0.163 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0048878 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0048878 Not Cancer Driver No 140 0.306 40 11 0.275 0
HTT HTT P42858 Huntingtin chr4 GO:0048878 Not Cancer Driver No 336 0.107 666 69 0.104 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0048878 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0048878 Not Cancer Driver No 61 0.115 251 28 0.112 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0048878 Not Cancer Driver No 12 0.092 7 0 0.0 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0048878 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL13 IL13 P35225 Interleukin-13 chr5 GO:0048878 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0048878 Not Cancer Driver No 30 0.111 35 6 0.171 0
INS INS P01308 Insulin chr11 GO:0048878 Not Cancer Driver No 15 0.136 5 1 0.2 22
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0048878 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0048878 Not Cancer Driver No 120 0.152 26 4 0.154 3
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0048878 Not Cancer Driver No 390 0.141 581 76 0.131 6
JPH2 JPH2 Q9BR39 Junctophilin-2 chr20 GO:0048878 Not Cancer Driver No 137 0.197 542 97 0.179 4
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0048878 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0048878 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0048878 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 GO:0048878 Not Cancer Driver No 28 0.272 24 2 0.083 0
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0048878 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0048878 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0048878 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0048878 Not Cancer Driver No 54 0.137 60 7 0.117 6
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 GO:0048878 Not Cancer Driver No 222 0.18 225 39 0.173 5
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0048878 Not Cancer Driver No 78 0.115 219 20 0.091 132
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 GO:0048878 Not Cancer Driver No 23 0.072 187 14 0.075 1
KCTD7 KCTD7 Q96MP8 BTB/POZ domain-containing protein KCTD7 chr7 GO:0048878 Not Cancer Driver No 37 0.128 45 1 0.022 4
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0048878 Not Cancer Driver No 61 0.153 277 50 0.181 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0048878 Census, Compendium Yes 357 0.263 275 55 0.2 2
KEL KEL P23276 Kell blood group glycoprotein chr7 GO:0048878 Compendium Yes 232 0.317 117 39 0.333 0
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0048878 Not Cancer Driver No 17 0.123 116 14 0.121 1
KLF15 KLF15 Q9UIH9 Krueppel-like factor 15 chr3 GO:0048878 Not Cancer Driver No 66 0.159 273 48 0.176 0
KRT1 KRT1 P04264 Keratin, type II cytoskeletal 1 chr12 GO:0048878 Not Cancer Driver No 133 0.207 426 98 0.23 20
KRT16 KRT16 P08779 Keratin, type I cytoskeletal 16 chr17 GO:0048878 Not Cancer Driver No 83 0.175 152 28 0.184 16
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0048878 Not Cancer Driver No 38 0.275 90 27 0.3 0
LETM1 LETM1 O95202 Mitochondrial proton/calcium exchanger protein chr4 GO:0048878 Not Cancer Driver No 77 0.104 286 28 0.098 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0048878 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIPG LIPG Q9Y5X9 Endothelial lipase chr18 GO:0048878 Not Cancer Driver No 90 0.18 59 7 0.119 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0048878 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:0048878 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:0048878 Not Cancer Driver No 39 0.113 0 0 0.0 3
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 GO:0048878 Not Cancer Driver No 85 0.159 66 11 0.167 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0048878 Not Cancer Driver No 105 0.13 32 3 0.094 0
LRRC8D LRRC8D Q7L1W4 Volume-regulated anion channel subunit LRRC8D chr1 GO:0048878 Not Cancer Driver No 99 0.115 98 18 0.184 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0048878 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSR_ENST00000361790 LSR Q86X29 Lipolysis-stimulated lipoprotein receptor chr19 GO:0048878 Not Cancer Driver No 89 0.137 330 42 0.127 0
MC3R MC3R P41968 Melanocortin receptor 3 chr20 GO:0048878 Not Cancer Driver No 96 0.297 0 0 0.0 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0048878 Not Cancer Driver No 41 0.117 13 0 0.0 0
MCUR1 MCUR1 Q96AQ8 Mitochondrial calcium uniporter regulator 1 chr6 GO:0048878 Not Cancer Driver No 30 0.084 65 0 0.0 0
MEN1 MEN1 O00255 Menin chr11 GO:0048878 Census, Compendium Yes 73 0.119 228 15 0.066 90
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0048878 Census, Compendium Yes 226 0.163 62 15 0.242 19
MICU1 MICU1 Q9BPX6 Calcium uptake protein 1, mitochondrial chr10 GO:0048878 Not Cancer Driver No 50 0.105 97 18 0.186 0
MICU2 MICU2 Q8IYU8 Calcium uptake protein 2, mitochondrial chr13 GO:0048878 Not Cancer Driver No 45 0.104 10 1 0.1 0
MLLT11 MLLT11 Q13015 Protein AF1q chr1 GO:0048878 Census Yes 15 0.167 18 5 0.278 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0048878 Not Cancer Driver No 106 0.124 554 66 0.119 0
MS4A1_ENST00000345732 MS4A1 P11836 B-lymphocyte antigen CD20 chr11 GO:0048878 Not Cancer Driver No 73 0.246 83 23 0.277 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0048878 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0048878 Not Cancer Driver No 104 0.287 8 1 0.125 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 GO:0048878 Not Cancer Driver No 269 0.146 505 68 0.135 14
MYOC MYOC Q99972 Myocilin chr1 GO:0048878 Not Cancer Driver No 92 0.183 196 43 0.219 58
NAPSA NAPSA O96009 Napsin-A chr19 GO:0048878 Not Cancer Driver No 58 0.138 14 1 0.071 0
NEDD4L NEDD4L Q96PU5 E3 ubiquitin-protein ligase NEDD4-like chr18 GO:0048878 Not Cancer Driver No 126 0.129 463 60 0.13 4
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0048878 Not Cancer Driver No 84 0.236 202 52 0.257 2
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0048878 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKIRAS1 NKIRAS1 Q9NYS0 NF-kappa-B inhibitor-interacting Ras-like protein 1 chr3 GO:0048878 Not Cancer Driver No 20 0.104 21 1 0.048 0
NKIRAS2_ENST00000393880 NKIRAS2 Q9NYR9 NF-kappa-B inhibitor-interacting Ras-like protein 2 chr17 GO:0048878 Not Cancer Driver No 23 0.12 27 3 0.111 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0048878 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0048878 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0048878 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPSR1_ENST00000360581 NPSR1 Q6W5P4 Neuropeptide S receptor chr7 GO:0048878 Not Cancer Driver No 111 0.299 9 7 0.778 0
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0048878 Not Cancer Driver No 63 0.146 185 24 0.13 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0048878 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0048878 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0048878 Not Cancer Driver No 111 0.228 78 18 0.231 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0048878 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0048878 Not Cancer Driver No 30 0.123 243 30 0.123 0
OAS1_ENST00000202917 OAS1 P00973 2'-5'-oligoadenylate synthase 1 chr12 GO:0048878 Not Cancer Driver No 67 0.168 71 12 0.169 0
OIT3 OIT3 Q8WWZ8 Oncoprotein-induced transcript 3 protein chr10 GO:0048878 Not Cancer Driver No 87 0.16 31 8 0.258 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0048878 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0048878 Not Cancer Driver No 81 0.219 0 0 0.0 0
ORMDL1_ENST00000392350 ORMDL1 Q9P0S3 ORM1-like protein 1 chr2 GO:0048878 Not Cancer Driver No 12 0.078 0 0 0.0 0
ORMDL2_ENST00000548974 ORMDL2 Q53FV1 ORM1-like protein 2 chr12 GO:0048878 Not Cancer Driver No 10 0.065 0 0 0.0 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0048878 Not Cancer Driver No 22 0.144 9 1 0.111 0
OTC OTC P00480 Ornithine transcarbamylase, mitochondrial chrX GO:0048878 Not Cancer Driver No 89 0.251 24 4 0.167 111
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0048878 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0048878 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0048878 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0048878 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0048878 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0048878 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0048878 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:0048878 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0048878 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0048878 Not Cancer Driver No 50 0.152 10 5 0.5 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:0048878 Census, Compendium Yes 126 0.351 23 5 0.217 0
PACS2_ENST00000325438 PACS2 Q86VP3 Phosphofurin acidic cluster sorting protein 2 chr14 GO:0048878 Not Cancer Driver No 122 0.137 460 59 0.128 1
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0048878 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0048878 Not Cancer Driver No 62 0.149 296 48 0.162 23
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0048878 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0048878 Not Cancer Driver No 91 0.142 139 13 0.094 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0048878 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0048878 Not Cancer Driver No 33 0.059 121 12 0.099 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0048878 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0048878 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R2_ENST00000617130 PIK3R2 O00459 Phosphatidylinositol 3-kinase regulatory subunit beta chr19 GO:0048878 Not Cancer Driver No 96 0.132 418 47 0.112 3
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0048878 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0048878 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0048878 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCZ1 PLCZ1 Q86YW0 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 chr12 GO:0048878 Not Cancer Driver No 151 0.248 37 20 0.541 1
PLEC PLEC Q15149 Plectin chr8 GO:0048878 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PML PML P29590 Protein PML chr15 GO:0048878 Census, Compendium Yes 112 0.127 312 34 0.109 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0048878 Census, Compendium Yes 179 0.162 214 31 0.145 2
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0048878 Not Cancer Driver No 43 0.086 402 30 0.075 4
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0048878 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0048878 Not Cancer Driver No 44 0.097 30 3 0.1 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0048878 Compendium Yes 85 0.163 140 27 0.193 7
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0048878 Not Cancer Driver No 37 0.121 0 0 0.0 23
PQLC2_ENST00000375155 SLC66A1 Q6ZP29 Lysosomal amino acid transporter 1 homolog chr1 GO:0048878 Not Cancer Driver No 41 0.141 0 0 0.0 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0048878 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0048878 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0048878 Census Yes 53 0.151 24 0 0.0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 GO:0048878 Not Cancer Driver No 50 0.142 26 6 0.231 4
PRKACG PRKACG P22612 cAMP-dependent protein kinase catalytic subunit gamma chr9 GO:0048878 Not Cancer Driver No 74 0.211 23 7 0.304 1
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0048878 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0048878 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTH PTH P01270 Parathyroid hormone chr11 GO:0048878 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0048878 Not Cancer Driver No 139 0.152 214 28 0.131 0
RAB20 RAB20 Q9NX57 Ras-related protein Rab-20 chr13 GO:0048878 Not Cancer Driver No 33 0.141 57 8 0.14 0
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 GO:0048878 Not Cancer Driver No 27 0.128 0 0 0.0 0
RAB39A RAB39A Q14964 Ras-related protein Rab-39A chr11 GO:0048878 Not Cancer Driver No 29 0.134 3 0 0.0 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0048878 Not Cancer Driver No 27 0.13 11 0 0.0 4
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0048878 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0048878 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0048878 Not Cancer Driver No 10 0.054 42 5 0.119 0
RAP1GDS1_ENST00000408927 RAP1GDS1 P52306 Rap1 GTPase-GDP dissociation stimulator 1 chr4 GO:0048878 Census, Compendium Yes 93 0.153 13 0 0.0 0
RCN3 RCN3 Q96D15 Reticulocalbin-3 chr19 GO:0048878 Not Cancer Driver No 44 0.134 243 39 0.16 0
RHAG RHAG Q02094 Ammonium transporter Rh type A chr6 GO:0048878 Not Cancer Driver No 102 0.249 0 0 0.0 6
RHBG RHBG Q9H310 Ammonium transporter Rh type B chr1 GO:0048878 Not Cancer Driver No 66 0.144 32 7 0.219 0
RHCE RHCE P18577 Blood group Rh(CE) polypeptide chr1 GO:0048878 Not Cancer Driver No 64 0.153 8 5 0.625 0
RHCG RHCG Q9UBD6 Ammonium transporter Rh type C chr15 GO:0048878 Not Cancer Driver No 74 0.154 19 2 0.105 0
RHD_ENST00000328664 RHD Q02161 Blood group Rh(D) polypeptide chr1 GO:0048878 Not Cancer Driver No 55 0.132 9 0 0.0 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0048878 Not Cancer Driver No 121 0.102 866 82 0.095 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0048878 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0048878 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0048878 Not Cancer Driver No 86 0.225 29 6 0.207 0
SCGN SCGN O76038 Secretagogin chr6 GO:0048878 Not Cancer Driver No 77 0.279 12 1 0.083 0
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0048878 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0048878 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0048878 Not Cancer Driver No 46 0.214 52 7 0.135 2
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0048878 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0048878 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0048878 Not Cancer Driver No 395 0.235 171 43 0.251 0
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0048878 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0048878 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0048878 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0048878 Not Cancer Driver No 129 0.199 57 11 0.193 0
SCT SCT P09683 Secretin chr11 GO:0048878 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:0048878 Not Cancer Driver No 74 0.168 18 1 0.056 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0048878 Not Cancer Driver No 10 0.106 47 6 0.128 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0048878 Not Cancer Driver No 51 0.122 57 5 0.088 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0048878 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0048878 Census Yes 81 0.234 68 22 0.324 0
SFTPD SFTPD P35247 Pulmonary surfactant-associated protein D chr10 GO:0048878 Not Cancer Driver No 66 0.176 274 53 0.193 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0048878 Compendium Yes 172 0.135 617 73 0.118 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0048878 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLAMF8 SLAMF8 Q9P0V8 SLAM family member 8 chr1 GO:0048878 Not Cancer Driver No 63 0.221 20 2 0.1 0
SLC11A1 SLC11A1 P49279 Natural resistance-associated macrophage protein 1 chr2 GO:0048878 Not Cancer Driver No 79 0.144 47 5 0.106 0
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 GO:0048878 Not Cancer Driver No 60 0.106 38 5 0.132 3
SLC12A1_ENST00000380993 SLC12A1 Q13621 Solute carrier family 12 member 1 chr15 GO:0048878 Not Cancer Driver No 199 0.181 143 35 0.245 2
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0048878 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A3_ENST00000563236 SLC12A3 P55017 Solute carrier family 12 member 3 chr16 GO:0048878 Not Cancer Driver No 146 0.143 124 16 0.129 117
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 GO:0048878 Not Cancer Driver No 122 0.112 171 17 0.099 0
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0048878 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0048878 Not Cancer Driver No 168 0.146 280 46 0.164 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 GO:0048878 Not Cancer Driver No 153 0.141 202 23 0.114 0
SLC12A8 SLC12A8 A0AV02 Solute carrier family 12 member 8 chr3 GO:0048878 Not Cancer Driver No 98 0.137 93 10 0.108 0
SLC12A9 SLC12A9 Q9BXP2 Solute carrier family 12 member 9 chr7 GO:0048878 Not Cancer Driver No 117 0.128 174 8 0.046 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0048878 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0048878 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC24A1 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0048878 Not Cancer Driver No 105 0.096 595 53 0.089 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0048878 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0048878 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A23 SLC25A23 Q9BV35 Calcium-binding mitochondrial carrier protein SCaMC-3 chr19 GO:0048878 Not Cancer Driver No 63 0.135 74 8 0.108 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0048878 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0048878 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC29A1_ENST00000371708 SLC29A1 Q99808 Equilibrative nucleoside transporter 1 chr6 GO:0048878 Not Cancer Driver No 51 0.112 27 4 0.148 0
SLC30A2_ENST00000374278 SLC30A2 Q9BRI3 Zinc transporter 2 chr1 GO:0048878 Not Cancer Driver No 46 0.142 42 5 0.119 2
SLC30A3 SLC30A3 Q99726 Zinc transporter 3 chr2 GO:0048878 Not Cancer Driver No 56 0.144 97 18 0.186 0
SLC30A4 SLC30A4 O14863 Zinc transporter 4 chr15 GO:0048878 Not Cancer Driver No 44 0.103 54 8 0.148 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0048878 Not Cancer Driver No 115 0.312 25 9 0.36 0
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0048878 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC34A2 SLC34A2 O95436 Sodium-dependent phosphate transport protein 2B chr4 GO:0048878 Census Yes 132 0.191 65 15 0.231 1
SLC34A3_ENST00000361134 SLC34A3 Q8N130 Sodium-dependent phosphate transport protein 2C chr9 GO:0048878 Not Cancer Driver No 56 0.093 63 9 0.143 6
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0048878 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC39A8 SLC39A8 Q9C0K1 Metal cation symporter ZIP8 chr4 GO:0048878 Not Cancer Driver No 45 0.098 22 2 0.091 5
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0048878 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLC41A1 SLC41A1 Q8IVJ1 Solute carrier family 41 member 1 chr1 GO:0048878 Not Cancer Driver No 68 0.133 103 15 0.146 1
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0048878 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0048878 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0048878 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0048878 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0048878 Not Cancer Driver No 263 0.284 152 35 0.23 0
SLC8B1 SLC8B1 Q6J4K2 Mitochondrial sodium/calcium exchanger protein chr12 GO:0048878 Not Cancer Driver No 70 0.12 0 0 0.0 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0048878 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0048878 Not Cancer Driver No 19 0.053 318 16 0.05 4
SLC9A4 SLC9A4 Q6AI14 Sodium/hydrogen exchanger 4 chr2 GO:0048878 Not Cancer Driver No 197 0.247 197 77 0.391 0
SLC9A7_ENST00000328306 SLC9A7 Q96T83 Sodium/hydrogen exchanger 7 chrX GO:0048878 Not Cancer Driver No 102 0.141 180 29 0.161 1
SLMAP SLMAP Q14BN4 Sarcolemmal membrane-associated protein chr3 GO:0048878 Not Cancer Driver No 77 0.093 464 38 0.082 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0048878 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0048878 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0048878 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNAPIN SNAPIN O95295 SNARE-associated protein Snapin chr1 GO:0048878 Not Cancer Driver No 9 0.066 62 5 0.081 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0048878 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0048878 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0048878 Not Cancer Driver No 28 0.059 400 24 0.06 4
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0048878 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0048878 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRI SRI P30626 Sorcin chr7 GO:0048878 Not Cancer Driver No 15 0.076 32 2 0.062 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0048878 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAU1 STAU1 O95793 Double-stranded RNA-binding protein Staufen homolog 1 chr20 GO:0048878 Not Cancer Driver No 77 0.133 456 63 0.138 0
STEAP2 STEAP2 Q8NFT2 Metalloreductase STEAP2 chr7 GO:0048878 Not Cancer Driver No 68 0.139 1 0 0.0 0
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0048878 Not Cancer Driver No 15 0.101 149 15 0.101 0
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0048878 Not Cancer Driver No 59 0.1 64 9 0.141 0
TBC1D20 TBC1D20 Q96BZ9 TBC1 domain family member 20 chr20 GO:0048878 Not Cancer Driver No 52 0.129 99 10 0.101 0
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0048878 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBXAS1_ENST00000448866 TBXAS1 P24557 Thromboxane-A synthase chr7 GO:0048878 Not Cancer Driver No 116 0.218 44 8 0.182 4
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0048878 Compendium Yes 68 0.082 102 6 0.059 5
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0048878 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0048878 Not Cancer Driver No 94 0.117 168 20 0.119 3
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0048878 Not Cancer Driver No 123 0.179 107 26 0.243 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0048878 Not Cancer Driver No 61 0.116 149 21 0.141 38
THADA_ENST00000405975 THADA Q6YHU6 Thyroid adenoma-associated protein chr2 GO:0048878 Not Cancer Driver No 204 0.104 63 6 0.095 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0048878 Not Cancer Driver No 24 0.149 5 0 0.0 0
TLCD1 TLCD1 Q96CP7 TLC domain-containing protein 1 chr17 GO:0048878 Not Cancer Driver No 30 0.121 0 0 0.0 0
TLCD2 TLCD2 A6NGC4 TLC domain-containing protein 2 chr17 GO:0048878 Not Cancer Driver No 1 0.004 35 1 0.029 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0048878 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMC8 TMC8 Q8IU68 Transmembrane channel-like protein 8 chr17 GO:0048878 Not Cancer Driver No 61 0.084 107 10 0.093 0
TMCO1 TMCO1 Q9UM00 Calcium load-activated calcium channel chr1 GO:0048878 Not Cancer Driver No 31 0.13 49 5 0.102 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 GO:0048878 Not Cancer Driver No 31 0.113 56 4 0.071 1
TMEM165 TMEM165 Q9HC07 Transmembrane protein 165 chr4 GO:0048878 Not Cancer Driver No 29 0.09 75 5 0.067 3
TMEM175 TMEM175 Q9BSA9 Endosomal/lysosomal potassium channel TMEM175 chr4 GO:0048878 Not Cancer Driver No 77 0.153 51 13 0.255 0
TMEM199 TMEM199 Q8N511 Transmembrane protein 199 chr17 GO:0048878 Not Cancer Driver No 24 0.115 54 5 0.093 3
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0048878 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0048878 Not Cancer Driver No 47 0.162 37 7 0.189 0
TMEM79_ENST00000295694 TMEM79 Q9BSE2 Transmembrane protein 79 chr1 GO:0048878 Not Cancer Driver No 56 0.142 149 20 0.134 0
TMEM9_ENST00000485839 TMEM9 Q9P0T7 Proton-transporting V-type ATPase complex assembly regulator TMEM9 chr1 GO:0048878 Not Cancer Driver No 22 0.12 23 3 0.13 0
TMPRSS11F TMPRSS11F Q6ZWK6 Transmembrane protease serine 11F chr4 GO:0048878 Not Cancer Driver No 119 0.272 29 13 0.448 0
TMPRSS3_ENST00000433957 TMPRSS3 P57727 Transmembrane protease serine 3 chr21 GO:0048878 Not Cancer Driver No 78 0.172 8 3 0.375 8
TMTC4_ENST00000376234 TMTC4 Q5T4D3 Protein O-mannosyl-transferase TMTC4 chr13 GO:0048878 Not Cancer Driver No 105 0.142 0 0 0.0 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0048878 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPP2_ENST00000376065 TPP2 P29144 Tripeptidyl-peptidase 2 chr13 GO:0048878 Not Cancer Driver No 147 0.118 218 40 0.183 1
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0048878 Not Cancer Driver No 59 0.205 244 54 0.221 0
TRDN TRDN Q13061 Triadin chr6 GO:0048878 Not Cancer Driver No 129 0.177 639 102 0.16 1
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0048878 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRPC1 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0048878 Not Cancer Driver No 143 0.18 52 11 0.212 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0048878 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0048878 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0048878 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPM7 TRPM7 Q96QT4 Transient receptor potential cation channel subfamily M member 7 chr15 GO:0048878 Not Cancer Driver No 199 0.107 455 60 0.132 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0048878 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0048878 Not Cancer Driver No 105 0.137 175 23 0.131 0
TRPV3_ENST00000576742 TRPV3 Q8NET8 Transient receptor potential cation channel subfamily V member 3 chr17 GO:0048878 Not Cancer Driver No 127 0.161 177 36 0.203 4
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0048878 Not Cancer Driver No 142 0.163 231 34 0.147 44
TRPV5 TRPV5 Q9NQA5 Transient receptor potential cation channel subfamily V member 5 chr7 GO:0048878 Not Cancer Driver No 206 0.283 68 14 0.206 0
TRPV6 TRPV6 Q9H1D0 Transient receptor potential cation channel subfamily V member 6 chr7 GO:0048878 Not Cancer Driver No 183 0.239 77 20 0.26 6
TSPOAP1 TSPOAP1 O95153 Peripheral-type benzodiazepine receptor-associated protein 1 chr17 GO:0048878 Not Cancer Driver No 268 0.144 1522 213 0.14 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0048878 Not Cancer Driver No 5 0.03 1 0 0.0 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0048878 Not Cancer Driver No 95 0.139 135 11 0.081 38
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0048878 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0048878 Not Cancer Driver No 31 0.1 11 3 0.273 0
UGCG UGCG Q16739 Ceramide glucosyltransferase chr9 GO:0048878 Not Cancer Driver No 37 0.094 0 0 0.0 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0048878 Not Cancer Driver No 214 0.135 448 77 0.172 0
UPK3A UPK3A O75631 Uroplakin-3a chr22 GO:0048878 Not Cancer Driver No 39 0.136 66 11 0.167 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0048878 Not Cancer Driver No 27 0.116 41 7 0.171 0
VGF VGF O15240 Neurosecretory protein VGF chr7 GO:0048878 Not Cancer Driver No 48 0.078 593 47 0.079 0
VPS33A VPS33A Q96AX1 Vacuolar protein sorting-associated protein 33A chr12 GO:0048878 Not Cancer Driver No 73 0.122 46 8 0.174 1
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0048878 Not Cancer Driver No 105 0.118 203 10 0.049 39
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0048878 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0048878 Not Cancer Driver No 55 0.158 11 1 0.091 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0048878 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0048878 Not Cancer Driver No 28 0.246 35 11 0.314 0
XK XK P51811 Endoplasmic reticulum membrane adapter protein XK chrX GO:0048878 Not Cancer Driver No 86 0.194 32 6 0.188 3
XPR1 XPR1 Q9UBH6 Xenotropic and polytropic retrovirus receptor 1 chr1 GO:0048878 Not Cancer Driver No 103 0.148 70 15 0.214 4
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0048878 Compendium Yes 151 0.204 433 80 0.185 4
ZNF236_ENST00000253159 ZNF236 Q9UL36 Zinc finger protein 236 chr18 GO:0048878 Not Cancer Driver No 270 0.146 977 152 0.156 0