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Total number of protein in "GO:0045936" GO term:  254

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0045936 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0045936 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0045936 Not Cancer Driver No 123 0.137 135 13 0.096 0
ADAR ADAR P55265 Double-stranded RNA-specific adenosine deaminase chr1 GO:0045936 Not Cancer Driver No 149 0.122 675 83 0.123 12
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0045936 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0045936 Not Cancer Driver No 39 0.16 92 21 0.228 1
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0045936 Not Cancer Driver No 36 0.118 87 9 0.103 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0045936 Census, Compendium Yes 108 0.225 158 24 0.152 4
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0045936 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0045936 Not Cancer Driver No 12 0.145 9 1 0.111 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0045936 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0045936 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0045936 Census Yes 30 0.156 39 2 0.051 0
BDKRB2 BDKRB2 P30411 B2 bradykinin receptor chr14 GO:0045936 Not Cancer Driver No 81 0.207 0 0 0.0 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:0045936 Not Cancer Driver No 16 0.086 133 10 0.075 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0045936 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BOD1L2 BOD1L2 Q8IYS8 Biorientation of chromosomes in cell division protein 1-like 2 chr18 GO:0045936 Not Cancer Driver No 29 0.169 144 26 0.181 0
CADM4 CADM4 Q8NFZ8 Cell adhesion molecule 4 chr19 GO:0045936 Not Cancer Driver No 48 0.124 94 9 0.096 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0045936 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0045936 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0045936 Not Cancer Driver No 17 0.114 115 10 0.087 3
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0045936 Census Yes 32 0.116 62 5 0.081 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0045936 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBFA2T3 CBFA2T3 O75081 Protein CBFA2T3 chr16 GO:0045936 Census, Compendium Yes 83 0.127 502 70 0.139 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0045936 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0045936 Census Yes 160 0.163 562 104 0.185 0
CBLC_ENST00000647358 CBLC Q9ULV8 E3 ubiquitin-protein ligase CBL-C chr19 GO:0045936 Census Yes 60 0.127 128 21 0.164 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0045936 Not Cancer Driver No 53 0.177 70 10 0.143 0
CDA CDA P32320 Cytidine deaminase chr1 GO:0045936 Not Cancer Driver No 21 0.144 8 0 0.0 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0045936 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0045936 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0045936 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0045936 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0045936 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0045936 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0045936 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0045936 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDKN2C_ENST00000371761 CDKN2C P42773 Cyclin-dependent kinase 4 inhibitor C chr1 GO:0045936 Census, Compendium Yes 23 0.137 49 6 0.122 0
CDKN2D_ENST00000335766 CDKN2D P55273 Cyclin-dependent kinase 4 inhibitor D chr19 GO:0045936 Not Cancer Driver No 17 0.102 44 3 0.068 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0045936 Census, Compendium Yes 12 0.034 342 12 0.035 1
CHMP6 CHMP6 Q96FZ7 Charged multivesicular body protein 6 chr17 GO:0045936 Not Cancer Driver No 26 0.129 88 16 0.182 0
CHORDC1 CHORDC1 Q9UHD1 Cysteine and histidine-rich domain-containing protein 1 chr11 GO:0045936 Not Cancer Driver No 47 0.142 119 17 0.143 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0045936 Not Cancer Driver No 27 0.138 70 12 0.171 0
CNKSR3 CNKSR3 Q6P9H4 Connector enhancer of kinase suppressor of ras 3 chr6 GO:0045936 Not Cancer Driver No 72 0.13 269 43 0.16 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0045936 Not Cancer Driver No 61 0.129 84 13 0.155 0
COX11 COX11 Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial chr17 GO:0045936 Not Cancer Driver No 21 0.076 51 4 0.078 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0045936 Not Cancer Driver No 72 0.121 100 12 0.12 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0045936 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0045936 Not Cancer Driver No 20 0.086 87 9 0.103 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0045936 Not Cancer Driver No 56 0.059 264 11 0.042 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0045936 Not Cancer Driver No 58 0.218 47 8 0.17 0
DMD DMD P11532 Dystrophin chrX GO:0045936 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0045936 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNAJA1 DNAJA1 P31689 DnaJ homolog subfamily A member 1 chr9 GO:0045936 Not Cancer Driver No 37 0.093 153 16 0.105 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0045936 Not Cancer Driver No 60 0.119 131 17 0.13 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0045936 Not Cancer Driver No 49 0.14 210 25 0.119 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0045936 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0045936 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0045936 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0045936 Not Cancer Driver No 84 0.457 0 0 0.0 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0045936 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0045936 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENG ENG P17813 Endoglin chr9 GO:0045936 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0045936 Not Cancer Driver No 148 0.16 101 5 0.05 33
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0045936 Not Cancer Driver No 55 0.119 297 37 0.125 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0045936 Not Cancer Driver No 33 0.098 19 0 0.0 4
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0045936 Not Cancer Driver No 75 0.144 243 38 0.156 1
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0045936 Not Cancer Driver No 43 0.108 272 33 0.121 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0045936 Not Cancer Driver No 15 0.139 39 7 0.179 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0045936 Not Cancer Driver No 10 0.093 58 4 0.069 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0045936 Census, Compendium Yes 59 0.102 157 19 0.121 5
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0045936 Compendium Yes 70 0.153 258 34 0.132 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0045936 Not Cancer Driver No 10 0.061 39 5 0.128 0
GCKR GCKR Q14397 Glucokinase regulatory protein chr2 GO:0045936 Not Cancer Driver No 98 0.157 85 27 0.318 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0045936 Not Cancer Driver No 67 0.088 434 42 0.097 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0045936 Compendium Yes 50 0.141 24 0 0.0 0
GPD1L GPD1L Q8N335 Glycerol-3-phosphate dehydrogenase 1-like protein chr3 GO:0045936 Not Cancer Driver No 40 0.114 13 1 0.077 0
GPRC5A GPRC5A Q8NFJ5 Retinoic acid-induced protein 3 chr12 GO:0045936 Not Cancer Driver No 43 0.12 19 4 0.211 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0045936 Not Cancer Driver No 25 0.136 77 12 0.156 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0045936 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0045936 Not Cancer Driver No 32 0.152 0 0 0.0 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0045936 Not Cancer Driver No 46 0.124 125 19 0.152 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0045936 Not Cancer Driver No 182 0.168 749 132 0.176 0
HEG1 HEG1 Q9ULI3 Protein HEG homolog 1 chr3 GO:0045936 Not Cancer Driver No 173 0.125 974 135 0.139 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0045936 Not Cancer Driver No 40 0.111 352 40 0.114 0
HEXIM2_ENST00000592695 HEXIM2 Q96MH2 Protein HEXIM2 chr17 GO:0045936 Not Cancer Driver No 35 0.122 286 35 0.122 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0045936 Compendium Yes 233 0.32 43 16 0.372 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0045936 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0045936 Not Cancer Driver No 128 0.105 559 51 0.091 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0045936 Not Cancer Driver No 24 0.124 42 4 0.095 3
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0045936 Not Cancer Driver No 52 0.11 8 1 0.125 0
IBTK IBTK Q9P2D0 Inhibitor of Bruton tyrosine kinase chr6 GO:0045936 Not Cancer Driver No 146 0.108 364 39 0.107 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045936 Not Cancer Driver No 51 0.307 23 6 0.261 0
IKBKB IKBKB O14920 Inhibitor of nuclear factor kappa-B kinase subunit beta chr8 GO:0045936 Census, Compendium Yes 106 0.14 211 31 0.147 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0045936 Not Cancer Driver No 49 0.153 84 12 0.143 0
INCA1_ENST00000576820 INCA1 Q0VD86 Protein INCA1 chr17 GO:0045936 Not Cancer Driver No 18 0.076 195 14 0.072 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0045936 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0045936 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0045936 Not Cancer Driver No 42 0.094 34 2 0.059 7
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0045936 Not Cancer Driver No 128 0.117 52 3 0.058 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:0045936 Not Cancer Driver No 138 0.133 202 30 0.149 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0045936 Census Yes 35 0.106 281 25 0.089 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0045936 Not Cancer Driver No 107 0.129 266 27 0.102 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0045936 Census, Compendium Yes 161 0.142 788 100 0.127 0
LATS2 LATS2 Q9NRM7 Serine/threonine-protein kinase LATS2 chr13 GO:0045936 Census, Compendium Yes 178 0.164 687 116 0.169 0
LDLRAD4 LDLRAD4 O15165 Low-density lipoprotein receptor class A domain-containing protein 4 chr18 GO:0045936 Not Cancer Driver No 66 0.216 191 39 0.204 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0045936 Not Cancer Driver No 15 0.06 133 6 0.045 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0045936 Not Cancer Driver No 162 0.362 277 115 0.415 0
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 GO:0045936 Not Cancer Driver No 85 0.159 66 11 0.167 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0045936 Not Cancer Driver No 120 0.135 447 70 0.157 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0045936 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0045936 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0045936 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRRK1 LRRK1 Q38SD2 Leucine-rich repeat serine/threonine-protein kinase 1 chr15 GO:0045936 Not Cancer Driver No 289 0.143 261 33 0.126 0
MAPK8IP1 MAPK8IP1 Q9UQF2 C-Jun-amino-terminal kinase-interacting protein 1 chr11 GO:0045936 Not Cancer Driver No 79 0.111 444 40 0.09 1
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0045936 Not Cancer Driver No 90 0.102 389 44 0.113 0
MEN1 MEN1 O00255 Menin chr11 GO:0045936 Census, Compendium Yes 73 0.119 228 15 0.066 90
MGAT5_ENST00000281923 MGAT5 Q09328 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A chr2 GO:0045936 Not Cancer Driver No 106 0.143 24 2 0.083 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0045936 Not Cancer Driver No 43 0.092 446 43 0.096 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0045936 Not Cancer Driver No 106 0.124 554 66 0.119 0
MVP MVP Q14764 Major vault protein chr16 GO:0045936 Not Cancer Driver No 141 0.158 285 31 0.109 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0045936 Not Cancer Driver No 284 0.303 853 263 0.308 0
NCAPG2_ENST00000356309 NCAPG2 Q86XI2 Condensin-2 complex subunit G2 chr7 GO:0045936 Not Cancer Driver No 113 0.099 72 8 0.111 3
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0045936 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0045936 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0045936 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0045936 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NF2 NF2 P35240 Merlin chr22 GO:0045936 Census, Compendium Yes 69 0.116 252 26 0.103 16
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0045936 Not Cancer Driver No 310 0.292 116 43 0.371 0
NOG NOG Q13253 Noggin chr17 GO:0045936 Not Cancer Driver No 22 0.095 86 9 0.105 20
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0045936 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPPA NPPA P01160 Natriuretic peptides A chr1 GO:0045936 Not Cancer Driver No 32 0.212 71 14 0.197 1
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0045936 Not Cancer Driver No 66 0.159 101 1 0.01 5
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0045936 Not Cancer Driver No 52 0.202 99 21 0.212 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0045936 Not Cancer Driver No 10 0.122 82 10 0.122 0
PAQR3 PAQR3 Q6TCH7 Progestin and adipoQ receptor family member 3 chr4 GO:0045936 Not Cancer Driver No 38 0.122 0 0 0.0 0
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0045936 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0045936 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0045936 Not Cancer Driver No 221 0.123 301 57 0.189 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0045936 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0045936 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0045936 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0045936 Census Yes 37 0.154 99 22 0.222 2
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0045936 Not Cancer Driver No 58 0.102 199 19 0.095 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0045936 Not Cancer Driver No 83 0.11 419 45 0.107 2
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0045936 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0045936 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0045936 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0045936 Not Cancer Driver No 62 0.147 111 23 0.207 0
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0045936 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0045936 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKIG_ENST00000372891 PKIG Q9Y2B9 cAMP-dependent protein kinase inhibitor gamma chr20 GO:0045936 Not Cancer Driver No 15 0.197 76 15 0.197 0
PLEK PLEK P08567 Pleckstrin chr2 GO:0045936 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0045936 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0045936 Not Cancer Driver No 87 0.144 119 13 0.109 0
PMEPA1 PMEPA1 Q969W9 Protein TMEPAI chr20 GO:0045936 Not Cancer Driver No 45 0.157 196 34 0.173 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0045936 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0045936 Census Yes 72 0.143 44 4 0.091 3
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0045936 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0045936 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R11 PPP1R11 O60927 E3 ubiquitin-protein ligase PPP1R11 chr6 GO:0045936 Not Cancer Driver No 17 0.135 126 17 0.135 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0045936 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0045936 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0045936 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0045936 Not Cancer Driver No 132 0.233 220 66 0.3 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0045936 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0045936 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0045936 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0045936 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0045936 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP4C_ENST00000561610 PPP4C P60510 Serine/threonine-protein phosphatase 4 catalytic subunit chr16 GO:0045936 Not Cancer Driver No 41 0.134 0 0 0.0 0
PPP4R2 PPP4R2 Q9NY27 Serine/threonine-protein phosphatase 4 regulatory subunit 2 chr3 GO:0045936 Not Cancer Driver No 32 0.077 314 26 0.083 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0045936 Not Cancer Driver No 100 0.118 240 33 0.138 0
PPP4R4 PPP4R4 Q6NUP7 Serine/threonine-protein phosphatase 4 regulatory subunit 4 chr14 GO:0045936 Not Cancer Driver No 164 0.188 209 43 0.206 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0045936 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0045936 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0045936 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0045936 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0045936 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0045936 Compendium Yes 79 0.117 43 9 0.209 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0045936 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0045936 Not Cancer Driver No 110 0.237 78 15 0.192 31
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0045936 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0045936 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0045936 Census Yes 42 0.093 12 0 0.0 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0045936 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0045936 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0045936 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0045936 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0045936 Census, Compendium Yes 315 0.241 462 107 0.232 0
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0045936 Not Cancer Driver No 51 0.102 186 22 0.118 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0045936 Not Cancer Driver No 16 0.082 39 4 0.103 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0045936 Not Cancer Driver No 34 0.107 13 0 0.0 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0045936 Not Cancer Driver No 73 0.076 505 48 0.095 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0045936 Not Cancer Driver No 90 0.276 126 44 0.349 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0045936 Census, Compendium Yes 140 0.151 282 32 0.113 22
RD3 RD3 Q7Z3Z2 Protein RD3 chr1 GO:0045936 Not Cancer Driver No 46 0.236 75 21 0.28 0
RGN RGN Q15493 Regucalcin chrX GO:0045936 Not Cancer Driver No 38 0.127 14 3 0.214 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0045936 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0045936 Not Cancer Driver No 145 0.104 732 81 0.111 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0045936 Not Cancer Driver No 147 0.151 403 57 0.141 0
SAMSN1_ENST00000400566 SAMSN1 Q9NSI8 SAM domain-containing protein SAMSN-1 chr21 GO:0045936 Not Cancer Driver No 112 0.3 291 85 0.292 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0045936 Not Cancer Driver No 117 0.136 132 15 0.114 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0045936 Not Cancer Driver No 142 0.364 47 28 0.596 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0045936 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0045936 Not Cancer Driver No 47 0.159 1 0 0.0 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0045936 Census, Compendium Yes 48 0.083 333 19 0.057 0
SH3BP5 SH3BP5 O60239 SH3 domain-binding protein 5 chr3 GO:0045936 Not Cancer Driver No 46 0.101 378 35 0.093 0
SH3BP5L SH3BP5L Q7L8J4 SH3 domain-binding protein 5-like chr1 GO:0045936 Not Cancer Driver No 62 0.158 376 57 0.152 0
SIRPA_ENST00000400068 SIRPA P78324 Tyrosine-protein phosphatase non-receptor type substrate 1 chr20 GO:0045936 Census, Compendium Yes 96 0.19 281 51 0.181 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0045936 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045936 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0045936 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0045936 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC4A1 SLC4A1 P02730 Band 3 anion transport protein chr17 GO:0045936 Not Cancer Driver No 153 0.168 130 23 0.177 39
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0045936 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0045936 Not Cancer Driver No 263 0.284 152 35 0.23 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0045936 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0045936 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNX25 SNX25 Q9H3E2 Sorting nexin-25 chr4 GO:0045936 Not Cancer Driver No 101 0.12 114 10 0.088 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0045936 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0045936 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0045936 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS4_ENST00000555846 SOCS4 Q8WXH5 Suppressor of cytokine signaling 4 chr14 GO:0045936 Not Cancer Driver No 43 0.098 136 13 0.096 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0045936 Not Cancer Driver No 84 0.157 297 46 0.155 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0045936 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0045936 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0045936 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0045936 Not Cancer Driver No 73 0.175 228 43 0.189 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0045936 Not Cancer Driver No 46 0.146 169 29 0.172 1
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0045936 Census, Compendium Yes 110 0.143 152 15 0.099 19
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0045936 Not Cancer Driver No 55 0.176 18 3 0.167 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0045936 Not Cancer Driver No 44 0.075 271 18 0.066 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0045936 Not Cancer Driver No 63 0.101 339 35 0.103 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0045936 Compendium Yes 61 0.18 285 52 0.182 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0045936 Not Cancer Driver No 63 0.152 47 8 0.17 3
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0045936 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0045936 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIPRL TIPRL O75663 TIP41-like protein chr1 GO:0045936 Not Cancer Driver No 25 0.092 25 3 0.12 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0045936 Not Cancer Driver No 24 0.119 25 4 0.16 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045936 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0045936 Census, Compendium Yes 98 0.124 231 33 0.143 1
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0045936 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0045936 Not Cancer Driver No 46 0.118 159 23 0.145 0
TTC36 TTC36 A6NLP5 Tetratricopeptide repeat protein 36 chr11 GO:0045936 Not Cancer Driver No 13 0.069 98 12 0.122 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0045936 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0045936 Not Cancer Driver No 13 0.086 68 6 0.088 0
VPS25 VPS25 Q9BRG1 Vacuolar protein-sorting-associated protein 25 chr17 GO:0045936 Not Cancer Driver No 16 0.091 10 0 0.0 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0045936 Not Cancer Driver No 6 0.013 336 6 0.018 0
WEE2 WEE2 P0C1S8 Wee1-like protein kinase 2 chr7 GO:0045936 Not Cancer Driver No 104 0.183 345 65 0.188 1
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0045936 Census Yes 32 0.125 41 3 0.073 0
ZFYVE28 ZFYVE28 Q9HCC9 Lateral signaling target protein 2 homolog chr4 GO:0045936 Not Cancer Driver No 132 0.149 420 67 0.16 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 GO:0045936 Not Cancer Driver No 75 0.141 346 49 0.142 0
ZNF675 ZNF675 Q8TD23 Zinc finger protein 675 chr19 GO:0045936 Not Cancer Driver No 114 0.201 91 19 0.209 0