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Total number of protein in "GO:0045935" GO term:  490

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0045935 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0045935 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0045935 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0045935 Not Cancer Driver No 51 0.129 6 2 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0045935 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0045935 Not Cancer Driver No 126 0.147 141 15 0.106 11
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0045935 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 GO:0045935 Not Cancer Driver No 62 0.033 1144 34 0.03 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0045935 Not Cancer Driver No 53 0.164 22 4 0.182 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0045935 Not Cancer Driver No 64 0.125 407 57 0.14 0
APLN APLN Q9ULZ1 Apelin chrX GO:0045935 Not Cancer Driver No 8 0.104 51 6 0.118 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0045935 Not Cancer Driver No 128 0.166 418 71 0.17 17
AR AR P10275 Androgen receptor chrX GO:0045935 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0045935 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0045935 Census Yes 77 0.098 511 56 0.11 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0045935 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0045935 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0045935 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0045935 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0045935 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0045935 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0045935 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0045935 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0045935 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0045935 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0045935 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0045935 Not Cancer Driver No 51 0.148 63 8 0.127 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0045935 Census Yes 30 0.156 39 2 0.051 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0045935 Not Cancer Driver No 153 0.103 840 87 0.104 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0045935 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0045935 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0045935 Census, Compendium Yes 66 0.124 21 0 0.0 8
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0045935 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0045935 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:0045935 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0045935 Not Cancer Driver No 90 0.133 399 45 0.113 4
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0045935 Census Yes 32 0.203 7 2 0.286 0
BUD23_ENST00000265758 BUD23 O43709 Probable 18S rRNA (guanine-N(7))-methyltransferase chr7 GO:0045935 Not Cancer Driver No 41 0.146 83 11 0.133 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0045935 Not Cancer Driver No 93 0.128 503 63 0.125 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0045935 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0045935 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0045935 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0045935 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0045935 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0045935 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0045935 Not Cancer Driver No 41 0.075 36 2 0.056 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0045935 Census Yes 42 0.191 18 10 0.556 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0045935 Not Cancer Driver No 39 0.141 56 6 0.107 2
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0045935 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0045935 Not Cancer Driver No 24 0.081 0 0 0.0 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0045935 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0045935 Not Cancer Driver No 3 0.009 276 2 0.007 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0045935 Not Cancer Driver No 56 0.115 166 17 0.102 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0045935 Not Cancer Driver No 82 0.176 201 33 0.164 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0045935 Not Cancer Driver No 107 0.22 253 74 0.292 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0045935 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0045935 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0045935 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0045935 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0045935 Not Cancer Driver No 13 0.107 7 0 0.0 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 GO:0045935 Not Cancer Driver No 19 0.11 129 13 0.101 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:0045935 Not Cancer Driver No 93 0.104 708 83 0.117 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0045935 Not Cancer Driver No 22 0.098 42 4 0.095 1
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0045935 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0045935 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0045935 Not Cancer Driver No 30 0.103 6 0 0.0 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0045935 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0045935 Census, Compendium Yes 66 0.095 414 28 0.068 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0045935 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0045935 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0045935 Not Cancer Driver No 96 0.208 338 67 0.198 1
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0045935 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0045935 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 GO:0045935 Compendium Yes 53 0.13 327 45 0.138 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0045935 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0045935 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0045935 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0045935 Census Yes 74 0.121 225 23 0.102 0
DEK DEK P35659 Protein DEK chr6 GO:0045935 Census Yes 47 0.125 297 41 0.138 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0045935 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0045935 Not Cancer Driver No 159 0.158 222 39 0.176 0
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 GO:0045935 Not Cancer Driver No 28 0.089 37 2 0.054 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0045935 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0045935 Not Cancer Driver No 62 0.121 145 29 0.2 24
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0045935 Not Cancer Driver No 71 0.246 223 57 0.256 1
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0045935 Not Cancer Driver No 49 0.105 269 28 0.104 0
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:0045935 Not Cancer Driver No 23 0.065 36 0 0.0 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0045935 Not Cancer Driver No 83 0.215 10 1 0.1 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0045935 Not Cancer Driver No 28 0.071 41 4 0.098 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0045935 Not Cancer Driver No 86 0.116 260 24 0.092 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0045935 Not Cancer Driver No 46 0.116 143 17 0.119 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0045935 Not Cancer Driver No 135 0.177 447 73 0.163 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0045935 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0045935 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0045935 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0045935 Not Cancer Driver No 116 0.118 899 101 0.112 0
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0045935 Census, Compendium Yes 67 0.108 446 53 0.119 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0045935 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0045935 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0045935 Not Cancer Driver No 41 0.096 6 1 0.167 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0045935 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0045935 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 GO:0045935 Not Cancer Driver No 104 0.124 515 68 0.132 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:0045935 Not Cancer Driver No 95 0.118 583 67 0.115 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0045935 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0045935 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0045935 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0045935 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0045935 Not Cancer Driver No 125 0.128 250 28 0.112 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0045935 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0045935 Not Cancer Driver No 68 0.154 78 9 0.115 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0045935 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0045935 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0045935 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0045935 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0045935 Not Cancer Driver No 58 0.132 154 18 0.117 1
FAM168A FAM168A Q92567 Protein FAM168A chr11 GO:0045935 Not Cancer Driver No 17 0.07 139 11 0.079 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0045935 Not Cancer Driver No 109 0.127 24 5 0.208 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0045935 Not Cancer Driver No 55 0.142 68 7 0.103 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0045935 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0045935 Census, Compendium Yes 113 0.141 162 28 0.173 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0045935 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FOS FOS P01100 Protein c-Fos chr14 GO:0045935 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0045935 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0045935 Compendium Yes 70 0.153 258 34 0.132 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0045935 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0045935 Census, Compendium Yes 70 0.104 595 68 0.114 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0045935 Not Cancer Driver No 67 0.133 53 10 0.189 3
FUS FUS P35637 RNA-binding protein FUS chr16 GO:0045935 Census Yes 51 0.097 524 51 0.097 20
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 GO:0045935 Not Cancer Driver No 71 0.174 111 19 0.171 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0045935 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0045935 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0045935 Not Cancer Driver No 40 0.101 268 24 0.09 9
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0045935 Not Cancer Driver No 327 0.122 117 16 0.137 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0045935 Not Cancer Driver No 10 0.049 97 4 0.041 1
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0045935 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0045935 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0045935 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0045935 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0045935 Not Cancer Driver No 32 0.143 77 14 0.182 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0045935 Not Cancer Driver No 56 0.102 257 21 0.082 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0045935 Not Cancer Driver No 59 0.169 2 0 0.0 1
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0045935 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0045935 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 GO:0045935 Not Cancer Driver No 49 0.102 147 20 0.136 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0045935 Not Cancer Driver No 75 0.112 263 26 0.099 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0045935 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0045935 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0045935 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0045935 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0045935 Not Cancer Driver No 17 0.152 0 0 0.0 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 GO:0045935 Not Cancer Driver No 32 0.077 413 32 0.077 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0045935 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0045935 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0045935 Not Cancer Driver No 59 0.088 622 57 0.092 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:0045935 Not Cancer Driver No 291 0.136 43 5 0.116 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0045935 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0045935 Census Yes 118 0.143 435 51 0.117 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0045935 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0045935 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0045935 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0045935 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMX2 HMX2 A2RU54 Homeobox protein HMX2 chr10 GO:0045935 Not Cancer Driver No 36 0.132 169 21 0.124 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0045935 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0045935 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0045935 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPLL HNRNPLL Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like chr2 GO:0045935 Not Cancer Driver No 37 0.068 149 13 0.087 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0045935 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0045935 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0045935 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0045935 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0045935 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0045935 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0045935 Not Cancer Driver No 149 0.231 251 52 0.207 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0045935 Not Cancer Driver No 105 0.223 44 8 0.182 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0045935 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0045935 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0045935 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045935 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0045935 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0045935 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0045935 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0045935 Census Yes 24 0.157 6 1 0.167 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0045935 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045935 Not Cancer Driver No 35 0.165 58 7 0.121 0
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 GO:0045935 Not Cancer Driver No 44 0.105 292 32 0.11 1
INS INS P01308 Insulin chr11 GO:0045935 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0045935 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0045935 Not Cancer Driver No 55 0.112 43 3 0.07 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0045935 Not Cancer Driver No 292 0.275 114 26 0.228 1
JUN JUN P05412 Transcription factor Jun chr1 GO:0045935 Census Yes 35 0.106 281 25 0.089 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0045935 Not Cancer Driver No 65 0.127 173 21 0.121 3
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0045935 Not Cancer Driver No 78 0.149 215 33 0.153 0
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0045935 Not Cancer Driver No 68 0.313 121 43 0.355 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0045935 Not Cancer Driver No 84 0.118 684 81 0.118 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0045935 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0045935 Compendium Yes 77 0.168 366 40 0.109 0
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0045935 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0045935 Not Cancer Driver No 37 0.08 142 9 0.063 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0045935 Not Cancer Driver No 58 0.1 350 44 0.126 0
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0045935 Not Cancer Driver No 74 0.111 611 69 0.113 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0045935 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0045935 Not Cancer Driver No 60 0.24 179 32 0.179 0
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0045935 Not Cancer Driver No 50 0.132 249 31 0.124 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0045935 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0045935 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0045935 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0045935 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0045935 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0045935 Census Yes 58 0.145 105 14 0.133 4
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0045935 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0045935 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0045935 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0045935 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0045935 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0045935 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0045935 Not Cancer Driver No 51 0.108 101 12 0.119 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0045935 Not Cancer Driver No 91 0.101 151 16 0.106 8
MBTD1_ENST00000415868 MBTD1 Q05BQ5 MBT domain-containing protein 1 chr17 GO:0045935 Not Cancer Driver No 66 0.105 119 8 0.067 0
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0045935 Not Cancer Driver No 63 0.121 16 4 0.25 9
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0045935 Not Cancer Driver No 22 0.115 171 21 0.123 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0045935 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0045935 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0045935 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0045935 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0045935 Not Cancer Driver No 74 0.128 274 29 0.106 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:0045935 Not Cancer Driver No 35 0.054 501 24 0.048 0
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0045935 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0045935 Census Yes 92 0.122 208 22 0.106 85
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0045935 Not Cancer Driver No 106 0.124 554 66 0.119 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0045935 Not Cancer Driver No 73 0.071 11 0 0.0 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:0045935 Not Cancer Driver No 43 0.119 163 17 0.104 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0045935 Not Cancer Driver No 44 0.153 136 21 0.154 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0045935 Not Cancer Driver No 110 0.11 101 8 0.079 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0045935 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRGBP MRGBP Q9NV56 MRG/MORF4L-binding protein chr20 GO:0045935 Not Cancer Driver No 27 0.132 147 23 0.156 0
MRNIP MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0045935 Not Cancer Driver No 44 0.128 268 35 0.131 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:0045935 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0045935 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0045935 Census Yes 92 0.099 37 4 0.108 70
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0045935 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0045935 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0045935 Census Yes 40 0.032 1050 19 0.018 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0045935 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 GO:0045935 Census, Compendium Yes 71 0.153 415 64 0.154 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0045935 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0045935 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0045935 Census Yes 45 0.141 246 33 0.134 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0045935 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0045935 Not Cancer Driver No 61 0.123 386 44 0.114 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0045935 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0045935 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0045935 Not Cancer Driver No 31 0.179 117 25 0.214 0
NBN NBN O60934 Nibrin chr8 GO:0045935 Census Yes 90 0.119 417 54 0.129 1
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0045935 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCL NCL P19338 Nucleolin chr2 GO:0045935 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0045935 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0045935 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0045935 Not Cancer Driver No 35 0.116 23 0 0.0 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0045935 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0045935 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0045935 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0045935 Not Cancer Driver No 48 0.148 181 22 0.122 55
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:0045935 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0045935 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0045935 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0045935 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0045935 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0045935 Not Cancer Driver No 336 0.168 464 79 0.17 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0045935 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0045935 Not Cancer Driver No 90 0.159 218 33 0.151 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0045935 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0045935 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0045935 Not Cancer Driver No 92 0.118 362 37 0.102 12
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0045935 Census, Compendium Yes 191 0.14 552 76 0.138 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0045935 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 GO:0045935 Census Yes 227 0.125 1008 107 0.106 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0045935 Not Cancer Driver No 90 0.105 267 31 0.116 0
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0045935 Not Cancer Driver No 46 0.309 48 14 0.292 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0045935 Not Cancer Driver No 148 0.133 788 120 0.152 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0045935 Not Cancer Driver No 51 0.086 14 2 0.143 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0045935 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0045935 Not Cancer Driver No 77 0.145 378 56 0.148 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0045935 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0045935 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0045935 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0045935 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0045935 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0045935 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0045935 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0045935 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0045935 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0045935 Census Yes 37 0.154 99 22 0.222 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0045935 Census, Compendium Yes 164 0.148 231 44 0.19 7
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0045935 Not Cancer Driver No 154 0.145 603 93 0.154 1
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0045935 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0045935 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0045935 Census, Compendium Yes 154 0.213 268 61 0.228 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0045935 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0045935 Not Cancer Driver No 13 0.167 78 13 0.167 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:0045935 Not Cancer Driver No 59 0.097 369 37 0.1 0
PML PML P29590 Protein PML chr15 GO:0045935 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0045935 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0045935 Not Cancer Driver No 86 0.11 115 10 0.087 2
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 GO:0045935 Not Cancer Driver No 157 0.111 746 78 0.105 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0045935 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0045935 Not Cancer Driver No 15 0.087 15 1 0.067 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0045935 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0045935 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0045935 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0045935 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0045935 Not Cancer Driver No 114 0.121 798 100 0.125 0
PRDM7_ENST00000449207 PRDM7 Q9NQW5 Histone-lysine N-methyltransferase PRDM7 chr16 GO:0045935 Not Cancer Driver No 62 0.126 280 26 0.093 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0045935 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0045935 Not Cancer Driver No 46 0.205 13 4 0.308 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0045935 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0045935 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0045935 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0045935 Compendium Yes 79 0.117 43 9 0.209 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0045935 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0045935 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0045935 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0045935 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRL PRL P01236 Prolactin chr6 GO:0045935 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0045935 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0045935 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRXL2C PRXL2C Q7RTV5 Peroxiredoxin-like 2C chr9 GO:0045935 Not Cancer Driver No 10 0.044 26 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0045935 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0045935 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0045935 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0045935 Census, Compendium Yes 315 0.241 462 107 0.232 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0045935 Not Cancer Driver No 150 0.126 640 77 0.12 3
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0045935 Not Cancer Driver No 51 0.102 186 22 0.118 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0045935 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0045935 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0045935 Not Cancer Driver No 42 0.124 47 5 0.106 3
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0045935 Not Cancer Driver No 31 0.128 40 6 0.15 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0045935 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0045935 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM20 RBM20 Q5T481 RNA-binding protein 20 chr10 GO:0045935 Not Cancer Driver No 55 0.045 957 41 0.043 10
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:0045935 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0045935 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX GO:0045935 Not Cancer Driver No 22 0.14 134 18 0.134 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0045935 Not Cancer Driver No 82 0.21 380 81 0.213 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 GO:0045935 Not Cancer Driver No 77 0.197 371 75 0.202 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0045935 Not Cancer Driver No 49 0.098 151 19 0.126 2
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0045935 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0045935 Not Cancer Driver No 37 0.185 24 5 0.208 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0045935 Compendium Yes 75 0.136 400 48 0.12 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0045935 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0045935 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0045935 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0045935 Not Cancer Driver No 38 0.112 20 1 0.05 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0045935 Not Cancer Driver No 9 0.066 81 7 0.086 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0045935 Not Cancer Driver No 20 0.146 3 0 0.0 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0045935 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:0045935 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 GO:0045935 Not Cancer Driver No 68 0.123 253 33 0.13 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0045935 Compendium Yes 82 0.122 277 39 0.141 4
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0045935 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0045935 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0045935 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0045935 Not Cancer Driver No 176 0.132 241 21 0.087 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0045935 Not Cancer Driver No 144 0.118 474 64 0.135 14
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0045935 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0045935 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0045935 Not Cancer Driver No 62 0.134 100 13 0.13 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0045935 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0045935 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0045935 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:0045935 Census, Compendium Yes 244 0.187 477 80 0.168 0
SF3B4 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 GO:0045935 Not Cancer Driver No 69 0.163 273 56 0.205 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0045935 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0045935 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0045935 Not Cancer Driver No 3 0.012 81 1 0.012 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0045935 Not Cancer Driver No 33 0.093 164 12 0.073 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0045935 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0045935 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 GO:0045935 Not Cancer Driver No 60 0.119 9 1 0.111 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0045935 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0045935 Not Cancer Driver No 67 0.124 139 18 0.129 1
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0045935 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0045935 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0045935 Not Cancer Driver No 112 0.095 725 76 0.105 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0045935 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0045935 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0045935 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0045935 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0045935 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0045935 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0045935 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0045935 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0045935 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0045935 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0045935 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 GO:0045935 Not Cancer Driver No 240 0.12 342 45 0.132 45
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0045935 Not Cancer Driver No 82 0.184 216 52 0.241 0
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0045935 Not Cancer Driver No 38 0.087 416 37 0.089 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0045935 Not Cancer Driver No 62 0.116 488 56 0.115 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0045935 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0045935 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0045935 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0045935 Not Cancer Driver No 79 0.111 344 43 0.125 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0045935 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0045935 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0045935 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0045935 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 GO:0045935 Not Cancer Driver No 50 0.184 189 40 0.212 0
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0045935 Not Cancer Driver No 17 0.215 0 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0045935 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0045935 Census, Compendium Yes 106 0.125 325 44 0.135 0
STH STH Q8IWL8 Saitohin chr17 GO:0045935 Not Cancer Driver No 13 0.102 55 5 0.091 0
STPG4 STPG4 Q8N801 Protein STPG4 chr2 GO:0045935 Not Cancer Driver No 32 0.129 132 17 0.129 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0045935 Not Cancer Driver No 72 0.092 140 12 0.086 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0045935 Not Cancer Driver No 51 0.123 202 15 0.074 27
TAZ_ENST00000612460 TAFAZZIN Q16635 Tafazzin chrX GO:0045935 Not Cancer Driver No 33 0.126 12 0 0.0 10
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0045935 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0045935 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0045935 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0045935 Not Cancer Driver No 52 0.122 157 24 0.153 1
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0045935 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0045935 Census Yes 110 0.097 212 16 0.075 31
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0045935 Census Yes 89 0.117 80 6 0.075 1
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0045935 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0045935 Not Cancer Driver No 63 0.152 47 8 0.17 3
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 GO:0045935 Census Yes 137 0.143 955 137 0.143 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0045935 Not Cancer Driver No 154 0.127 367 51 0.139 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0045935 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045935 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0045935 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0045935 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0045935 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0045935 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0045935 Not Cancer Driver No 117 0.1 255 24 0.094 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:0045935 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:0045935 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:0045935 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0045935 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0045935 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0045935 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0045935 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 GO:0045935 Not Cancer Driver No 45 0.16 253 41 0.162 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0045935 Not Cancer Driver No 59 0.205 244 54 0.221 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0045935 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0045935 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 GO:0045935 Not Cancer Driver No 15 0.12 17 2 0.118 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0045935 Census, Compendium Yes 554 0.144 402 59 0.147 8
TTC5 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0045935 Not Cancer Driver No 65 0.148 151 19 0.126 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0045935 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0045935 Not Cancer Driver No 159 0.106 659 74 0.112 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 GO:0045935 Compendium Yes 78 0.164 191 28 0.147 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0045935 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0045935 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0045935 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0045935 Not Cancer Driver No 100 0.131 567 77 0.136 1
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0045935 Not Cancer Driver No 146 0.129 329 36 0.109 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0045935 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0045935 Not Cancer Driver No 30 0.087 326 29 0.089 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0045935 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0045935 Census, Compendium Yes 339 0.133 405 51 0.126 1
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:0045935 Not Cancer Driver No 49 0.095 39 4 0.103 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0045935 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0045935 Not Cancer Driver No 27 0.116 41 7 0.171 0
VPS72 VPS72 Q15906 Vacuolar protein sorting-associated protein 72 homolog chr1 GO:0045935 Not Cancer Driver No 43 0.118 329 37 0.112 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0045935 Census, Compendium Yes 75 0.149 400 55 0.138 30
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:0045935 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0045935 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:0045935 Not Cancer Driver No 67 0.081 87 7 0.08 0
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0045935 Not Cancer Driver No 66 0.12 232 29 0.125 4
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0045935 Census, Compendium Yes 164 0.115 373 41 0.11 2
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0045935 Not Cancer Driver No 19 0.073 169 9 0.053 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0045935 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0045935 Not Cancer Driver No 87 0.119 118 11 0.093 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 GO:0045935 Not Cancer Driver No 23 0.101 17 1 0.059 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0045935 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0045935 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0045935 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0045935 Compendium Yes 151 0.204 433 80 0.185 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0045935 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0045935 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 GO:0045935 Not Cancer Driver No 139 0.146 929 134 0.144 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0045935 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 GO:0045935 Not Cancer Driver No 142 0.157 344 63 0.183 0
ZCWPW1 ZCWPW1 Q9H0M4 Zinc finger CW-type PWWP domain protein 1 chr7 GO:0045935 Not Cancer Driver No 90 0.139 456 61 0.134 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0045935 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0045935 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0045935 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0045935 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0045935 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZSWIM8_ENST00000605216 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 GO:0045935 Not Cancer Driver No 204 0.111 877 103 0.117 0