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Total number of protein in "GO:0045597" GO term:  704

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAMDC_ENST00000526415 AAMDC Q9H7C9 Mth938 domain-containing protein chr11 GO:0045597 Not Cancer Driver No 13 0.107 47 5 0.106 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0045597 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0045597 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:0045597 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0045597 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0045597 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0045597 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0045597 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0045597 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0045597 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0045597 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0045597 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0045597 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAMTS20 ADAMTS20 P59510 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 GO:0045597 Not Cancer Driver No 495 0.259 120 33 0.275 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0045597 Not Cancer Driver No 288 0.149 235 38 0.162 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0045597 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADIG ADIG Q0VDE8 Adipogenin chr20 GO:0045597 Not Cancer Driver No 18 0.225 0 0 0.0 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0045597 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIRF ADIRF Q15847 Adipogenesis regulatory factor chr10 GO:0045597 Not Cancer Driver No 8 0.105 64 8 0.125 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0045597 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0045597 Not Cancer Driver No 130 0.118 615 66 0.107 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0045597 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0045597 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0045597 Not Cancer Driver No 95 0.265 0 0 0.0 1
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0045597 Not Cancer Driver No 120 0.1 500 56 0.112 6
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0045597 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0045597 Not Cancer Driver No 11 0.057 125 9 0.072 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0045597 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0045597 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALX1 ALX1 Q15699 ALX homeobox protein 1 chr12 GO:0045597 Not Cancer Driver No 75 0.23 190 48 0.253 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0045597 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0045597 Not Cancer Driver No 104 0.127 146 26 0.178 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0045597 Not Cancer Driver No 145 0.138 239 33 0.138 0
ANKRD54 ANKRD54 Q6NXT1 Ankyrin repeat domain-containing protein 54 chr22 GO:0045597 Not Cancer Driver No 26 0.087 188 12 0.064 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0045597 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP3B1 AP3B1 O00203 AP-3 complex subunit beta-1 chr5 GO:0045597 Not Cancer Driver No 126 0.115 316 31 0.098 1
AP3D1_ENST00000345016 AP3D1 O14617 AP-3 complex subunit delta-1 chr19 GO:0045597 Not Cancer Driver No 138 0.12 404 59 0.146 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0045597 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0045597 Not Cancer Driver No 1022 0.224 315 72 0.229 3
AR AR P10275 Androgen receptor chrX GO:0045597 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0045597 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0045597 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0045597 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 GO:0045597 Not Cancer Driver No 40 0.133 49 8 0.163 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0045597 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASB4 ASB4 Q9Y574 Ankyrin repeat and SOCS box protein 4 chr7 GO:0045597 Not Cancer Driver No 82 0.192 19 1 0.053 0
ASPA ASPA P45381 Aspartoacylase chr17 GO:0045597 Not Cancer Driver No 58 0.185 3 0 0.0 42
ASPM ASPM Q8IZT6 Abnormal spindle-like microcephaly-associated protein chr1 GO:0045597 Not Cancer Driver No 554 0.159 424 67 0.158 0
ASXL2_ENST00000435504 ASXL2 Q76L83 Putative Polycomb group protein ASXL2 chr2 GO:0045597 Census, Compendium Yes 209 0.146 1275 174 0.136 0
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0045597 Not Cancer Driver No 63 0.178 327 55 0.168 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0045597 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP11A ATP11A P98196 Phospholipid-transporting ATPase IH chr13 GO:0045597 Not Cancer Driver No 171 0.151 77 17 0.221 0
ATRAID_ENST00000606999 ATRAID Q6UW56 All-trans retinoic acid-induced differentiation factor chr2 GO:0045597 Not Cancer Driver No 15 0.066 9 2 0.222 0
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0045597 Not Cancer Driver No 36 0.089 178 21 0.118 0
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0045597 Census, Compendium Yes 114 0.135 547 77 0.141 0
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0045597 Not Cancer Driver No 168 0.188 341 64 0.188 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0045597 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0045597 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAMBI BAMBI Q13145 BMP and activin membrane-bound inhibitor homolog chr10 GO:0045597 Not Cancer Driver No 42 0.162 31 7 0.226 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0045597 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0045597 Census, Compendium Yes 134 0.19 328 67 0.204 0
BCL9L BCL9L Q86UU0 B-cell CLL/lymphoma 9-like protein chr11 GO:0045597 Census, Compendium Yes 200 0.133 1495 200 0.134 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0045597 Not Cancer Driver No 47 0.19 79 19 0.241 1
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0045597 Not Cancer Driver No 88 0.161 267 38 0.142 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0045597 Not Cancer Driver No 65 0.11 456 42 0.092 5
BLOC1S5 BLOC1S5 Q8TDH9 Biogenesis of lysosome-related organelles complex 1 subunit 5 chr6 GO:0045597 Not Cancer Driver No 15 0.08 153 13 0.085 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0045597 Not Cancer Driver No 12 0.07 111 11 0.099 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0045597 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0045597 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0045597 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0045597 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0045597 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0045597 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0045597 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0045597 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0045597 Not Cancer Driver No 195 0.196 530 111 0.209 0
BOC_ENST00000355385 BOC Q9BWV1 Brother of CDO chr3 GO:0045597 Not Cancer Driver No 175 0.157 568 92 0.162 0
BRD1_ENST00000216267 BRD1 O95696 Bromodomain-containing protein 1 chr22 GO:0045597 Not Cancer Driver No 171 0.162 425 68 0.16 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0045597 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0045597 Census, Compendium Yes 147 0.223 114 27 0.237 110
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0045597 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0045597 Not Cancer Driver No 14 0.05 103 6 0.058 2
CALR CALR P27797 Calreticulin chr19 GO:0045597 Census Yes 45 0.108 245 31 0.127 0
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0045597 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0045597 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAPRIN1_ENST00000532820 CAPRIN1 Q14444 Caprin-1 chr11 GO:0045597 Not Cancer Driver No 84 0.118 603 72 0.119 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 GO:0045597 Not Cancer Driver No 62 0.102 102 10 0.098 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0045597 Not Cancer Driver No 171 0.125 537 87 0.162 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0045597 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0045597 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0045597 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0045597 Census, Compendium Yes 39 0.214 94 17 0.181 0
CCDC3 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0045597 Not Cancer Driver No 40 0.148 68 18 0.265 0
CCDC71L CCDC71L Q8N9Z2 Coiled-coil domain-containing protein 71L chr7 GO:0045597 Not Cancer Driver No 3 0.013 193 2 0.01 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0045597 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0045597 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0045597 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0045597 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0045597 Not Cancer Driver No 69 0.194 14 5 0.357 0
CD27 CD27 P26842 CD27 antigen chr12 GO:0045597 Not Cancer Driver No 30 0.115 92 11 0.12 1
CD34 CD34 P28906 Hematopoietic progenitor cell antigen CD34 chr1 GO:0045597 Not Cancer Driver No 65 0.169 221 34 0.154 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0045597 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0045597 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD46_ENST00000358170 CD46 P15529 Membrane cofactor protein chr1 GO:0045597 Not Cancer Driver No 53 0.135 52 4 0.077 5
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0045597 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0045597 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD83 CD83 Q01151 CD83 antigen chr6 GO:0045597 Not Cancer Driver No 24 0.117 48 8 0.167 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0045597 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0045597 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0045597 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0045597 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0045597 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0045597 Not Cancer Driver No 165 0.172 685 120 0.175 18
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0045597 Not Cancer Driver No 15 0.109 67 3 0.045 0
CDON CDON Q4KMG0 Cell adhesion molecule-related/down-regulated by oncogenes chr11 GO:0045597 Not Cancer Driver No 183 0.142 441 63 0.143 5
CDS1 CDS1 Q92903 Phosphatidate cytidylyltransferase 1 chr4 GO:0045597 Not Cancer Driver No 73 0.158 66 9 0.136 0
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 GO:0045597 Census, Compendium Yes 39 0.125 271 35 0.129 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0045597 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0045597 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0045597 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPD CEBPD P49716 CCAAT/enhancer-binding protein delta chr8 GO:0045597 Not Cancer Driver No 5 0.019 234 4 0.017 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0045597 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0045597 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0045597 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0045597 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLIC1_ENST00000375779 CLIC1 O00299 Chloride intracellular channel protein 1 chr6 GO:0045597 Not Cancer Driver No 32 0.133 27 5 0.185 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0045597 Not Cancer Driver No 107 0.287 24 13 0.542 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0045597 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0045597 Compendium Yes 383 0.188 151 42 0.278 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0045597 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0045597 Not Cancer Driver No 155 0.121 72 0 0.0 5
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0045597 Census Yes 25 0.076 277 23 0.083 0
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0045597 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0045597 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0045597 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0045597 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0045597 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0045597 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0045597 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0045597 Not Cancer Driver No 62 0.149 133 18 0.135 0
CSPG5 CSPG5 O95196 Chondroitin sulfate proteoglycan 5 chr3 GO:0045597 Not Cancer Driver No 75 0.133 397 46 0.116 0
CTH CTH P32929 Cystathionine gamma-lyase chr1 GO:0045597 Not Cancer Driver No 45 0.111 49 6 0.122 2
CTHRC1 CTHRC1 Q96CG8 Collagen triple helix repeat-containing protein 1 chr8 GO:0045597 Not Cancer Driver No 31 0.128 62 5 0.081 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0045597 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBIP1_ENST00000377258 CTNNBIP1 Q9NSA3 Beta-catenin-interacting protein 1 chr1 GO:0045597 Not Cancer Driver No 8 0.099 64 7 0.109 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0045597 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0045597 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0045597 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0045597 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0045597 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL9 CXCL9 Q07325 C-X-C motif chemokine 9 chr4 GO:0045597 Not Cancer Driver No 32 0.256 38 16 0.421 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0045597 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0045597 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0045597 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0045597 Not Cancer Driver No 71 0.14 79 13 0.165 18
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0045597 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0045597 Not Cancer Driver No 102 0.114 485 61 0.126 4
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0045597 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0045597 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCSTAMP DCSTAMP Q9H295 Dendritic cell-specific transmembrane protein chr8 GO:0045597 Compendium Yes 150 0.319 6 3 0.5 0
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0045597 Not Cancer Driver No 113 0.218 19 4 0.211 2
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0045597 Census Yes 192 0.225 118 34 0.288 7
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0045597 Not Cancer Driver No 159 0.158 222 39 0.176 0
DICER1 DICER1 Q9UPY3 Endoribonuclease Dicer chr14 GO:0045597 Census, Compendium Yes 264 0.137 362 45 0.124 4
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0045597 Not Cancer Driver No 132 0.155 514 82 0.16 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0045597 Not Cancer Driver No 58 0.218 47 8 0.17 0
DKKL1 DKKL1 Q9UK85 Dickkopf-like protein 1 chr19 GO:0045597 Not Cancer Driver No 44 0.182 136 31 0.228 0
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0045597 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0045597 Not Cancer Driver No 46 0.14 262 38 0.145 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0045597 Not Cancer Driver No 25 0.046 325 19 0.058 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0045597 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0045597 Census Yes 138 0.159 270 43 0.159 22
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0045597 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0045597 Not Cancer Driver No 278 0.149 330 45 0.136 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0045597 Not Cancer Driver No 127 0.287 124 45 0.363 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0045597 Not Cancer Driver No 652 0.324 603 201 0.333 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0045597 Not Cancer Driver No 81 0.168 135 24 0.178 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0045597 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0045597 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0045597 Not Cancer Driver No 69 0.29 140 44 0.314 3
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0045597 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFEMP2 EFEMP2 O95967 EGF-containing fibulin-like extracellular matrix protein 2 chr11 GO:0045597 Not Cancer Driver No 67 0.151 41 4 0.098 8
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0045597 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0045597 Not Cancer Driver No 42 0.126 97 15 0.155 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0045597 Compendium Yes 90 0.189 352 59 0.168 11
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0045597 Not Cancer Driver No 60 0.155 252 46 0.183 0
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0045597 Not Cancer Driver No 104 0.115 382 43 0.113 0
ENG ENG P17813 Endoglin chr9 GO:0045597 Not Cancer Driver No 60 0.091 114 15 0.132 32
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0045597 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0045597 Not Cancer Driver No 186 0.176 119 17 0.143 7
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0045597 Not Cancer Driver No 68 0.154 78 9 0.115 0
ETV2_ENST00000403402 ETV2 O00321 ETS translocation variant 2 chr19 GO:0045597 Not Cancer Driver No 23 0.067 227 15 0.066 0
ETV4_ENST00000591713 ETV4 P43268 ETS translocation variant 4 chr17 GO:0045597 Census, Compendium Yes 44 0.091 319 26 0.082 0
EVI2B_ENST00000577894 EVI2B P34910 Protein EVI2B chr17 GO:0045597 Not Cancer Driver No 63 0.141 373 55 0.147 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0045597 Census, Compendium Yes 120 0.161 284 44 0.155 11
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0045597 Not Cancer Driver No 47 0.157 72 15 0.208 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0045597 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0045597 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM20C FAM20C Q8IXL6 Extracellular serine/threonine protein kinase FAM20C chr7 GO:0045597 Not Cancer Driver No 33 0.057 188 3 0.016 9
FAM210B FAM210B Q96KR6 Protein FAM210B, mitochondrial chr20 GO:0045597 Not Cancer Driver No 10 0.052 32 0 0.0 0
FAXDC2 FAXDC2 Q96IV6 Fatty acid hydroxylase domain-containing protein 2 chr5 GO:0045597 Not Cancer Driver No 39 0.117 9 0 0.0 0
FBN2_ENST00000262464 FBN2 P35556 Fibrillin-2 chr5 GO:0045597 Compendium Yes 607 0.208 135 24 0.178 30
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0045597 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0045597 Not Cancer Driver No 48 0.107 113 13 0.115 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0045597 Not Cancer Driver No 68 0.114 120 4 0.033 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0045597 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0045597 Census Yes 103 0.125 245 34 0.139 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0045597 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGA FGA P02671 Fibrinogen alpha chain chr4 GO:0045597 Not Cancer Driver No 245 0.283 522 149 0.285 7
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0045597 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0045597 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF20 FGF20 Q9NP95 Fibroblast growth factor 20 chr8 GO:0045597 Not Cancer Driver No 25 0.118 57 3 0.053 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0045597 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0045597 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0045597 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0045597 Not Cancer Driver No 81 0.179 53 8 0.151 8
FLNA FLNA P21333 Filamin-A chrX GO:0045597 Census Yes 416 0.157 1456 214 0.147 28
FN1 FN1 P02751 Fibronectin chr2 GO:0045597 Compendium Yes 394 0.159 1243 185 0.149 8
FNDC5_ENST00000640867 FNDC5 Q8NAU1 Fibronectin type III domain-containing protein 5 chr1 GO:0045597 Not Cancer Driver No 17 0.08 74 8 0.108 0
FOS FOS P01100 Protein c-Fos chr14 GO:0045597 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0045597 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0045597 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0045597 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXN1 FOXN1 O15353 Forkhead box protein N1 chr17 GO:0045597 Not Cancer Driver No 90 0.139 483 65 0.135 2
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0045597 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0045597 Not Cancer Driver No 38 0.088 186 16 0.086 10
FRZB FRZB Q92765 Secreted frizzled-related protein 3 chr2 GO:0045597 Not Cancer Driver No 58 0.178 31 6 0.194 1
FZD3_ENST00000240093 FZD3 Q9NPG1 Frizzled-3 chr8 GO:0045597 Not Cancer Driver No 64 0.096 141 13 0.092 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0045597 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0045597 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0045597 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0045597 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0045597 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0045597 Not Cancer Driver No 57 0.096 476 51 0.107 10
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0045597 Not Cancer Driver No 40 0.1 3 0 0.0 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0045597 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0045597 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0045597 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0045597 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0045597 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0045597 Not Cancer Driver No 47 0.223 83 18 0.217 2
GDPD2_ENST00000374382 GDPD2 Q9HCC8 Glycerophosphoinositol inositolphosphodiesterase GDPD2 chrX GO:0045597 Not Cancer Driver No 96 0.178 43 15 0.349 0
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0045597 Not Cancer Driver No 65 0.15 288 42 0.146 62
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0045597 Not Cancer Driver No 173 0.271 229 66 0.288 19
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0045597 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0045597 Not Cancer Driver No 33 0.075 225 10 0.044 6
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0045597 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0045597 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLIPR2 GLIPR2 Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 chr9 GO:0045597 Not Cancer Driver No 16 0.104 77 10 0.13 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0045597 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GPC1 GPC1 P35052 Glypican-1 chr2 GO:0045597 Not Cancer Driver No 58 0.104 166 14 0.084 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0045597 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0045597 Not Cancer Driver No 42 0.115 45 1 0.022 1
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0045597 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0045597 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0045597 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0045597 Not Cancer Driver No 44 0.145 210 26 0.124 1
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0045597 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0045597 Not Cancer Driver No 59 0.159 171 32 0.187 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0045597 Not Cancer Driver No 7 0.083 4 0 0.0 4
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0045597 Not Cancer Driver No 100 0.181 17 7 0.412 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0045597 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0045597 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0045597 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0045597 Not Cancer Driver No 46 0.094 145 14 0.097 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0045597 Not Cancer Driver No 37 0.132 226 32 0.142 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0045597 Compendium Yes 233 0.32 43 16 0.372 0
HIF1AN HIF1AN Q9NWT6 Hypoxia-inducible factor 1-alpha inhibitor chr10 GO:0045597 Not Cancer Driver No 37 0.106 77 9 0.117 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0045597 Census Yes 118 0.143 435 51 0.117 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0045597 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0045597 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-G_ENST00000360323 HLA-G P17693 HLA class I histocompatibility antigen, alpha chain G chr6 GO:0045597 Not Cancer Driver No 94 0.278 85 22 0.259 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0045597 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0045597 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0045597 Not Cancer Driver No 38 0.182 207 38 0.184 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0045597 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOPX_ENST00000317745 HOPX Q9BPY8 Homeodomain-only protein chr4 GO:0045597 Not Cancer Driver No 13 0.178 48 10 0.208 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0045597 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA5 HOXA5 P20719 Homeobox protein Hox-A5 chr7 GO:0045597 Not Cancer Driver No 43 0.159 209 37 0.177 0
HOXB4 HOXB4 P17483 Homeobox protein Hox-B4 chr17 GO:0045597 Not Cancer Driver No 41 0.163 210 33 0.157 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0045597 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF4 HSF4 Q9ULV5 Heat shock factor protein 4 chr16 GO:0045597 Not Cancer Driver No 37 0.075 327 25 0.076 4
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0045597 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0045597 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0045597 Not Cancer Driver No 15 0.023 200 5 0.025 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0045597 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0045597 Not Cancer Driver No 140 0.306 40 11 0.275 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0045597 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFITM1_ENST00000528780 IFITM1 P13164 Interferon-induced transmembrane protein 1 chr11 GO:0045597 Not Cancer Driver No 19 0.152 0 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0045597 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0045597 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0045597 Not Cancer Driver No 41 0.141 103 25 0.243 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0045597 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0045597 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0045597 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL12RB1_ENST00000593993 IL12RB1 P42701 Interleukin-12 receptor subunit beta-1 chr19 GO:0045597 Not Cancer Driver No 108 0.163 207 38 0.184 1
IL13 IL13 P35225 Interleukin-13 chr5 GO:0045597 Not Cancer Driver No 20 0.137 0 0 0.0 0
IL15RA_ENST00000379977 IL15RA Q13261 Interleukin-15 receptor subunit alpha chr10 GO:0045597 Not Cancer Driver No 40 0.15 173 32 0.185 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0045597 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0045597 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0045597 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0045597 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0045597 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0045597 Census Yes 24 0.157 6 1 0.167 0
IL20_ENST00000367096 IL20 Q9NYY1 Interleukin-20 chr1 GO:0045597 Not Cancer Driver No 30 0.17 0 0 0.0 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0045597 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0045597 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0045597 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0045597 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0045597 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0045597 Not Cancer Driver No 13 0.097 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0045597 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0045597 Not Cancer Driver No 55 0.118 165 23 0.139 1
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0045597 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0045597 Not Cancer Driver No 29 0.164 19 4 0.211 0
IL7R IL7R P16871 Interleukin-7 receptor subunit alpha chr5 GO:0045597 Census, Compendium Yes 177 0.386 88 48 0.545 1
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0045597 Not Cancer Driver No 45 0.1 71 9 0.127 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0045597 Not Cancer Driver No 148 0.347 154 63 0.409 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0045597 Not Cancer Driver No 176 0.148 578 90 0.156 0
INS INS P01308 Insulin chr11 GO:0045597 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0045597 Not Cancer Driver No 25 0.049 359 12 0.033 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0045597 Not Cancer Driver No 12 0.073 24 2 0.083 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0045597 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0045597 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0045597 Not Cancer Driver No 31 0.085 185 17 0.092 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0045597 Not Cancer Driver No 28 0.061 216 7 0.032 0
ITPKB_ENST00000272117 ITPKB P27987 Inositol-trisphosphate 3-kinase B chr1 GO:0045597 Not Cancer Driver No 148 0.156 719 119 0.166 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0045597 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0045597 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUNB JUNB P17275 Transcription factor JunB chr19 GO:0045597 Not Cancer Driver No 20 0.058 305 16 0.052 0
JUND JUND P17535 Transcription factor JunD chr19 GO:0045597 Not Cancer Driver No 21 0.061 313 19 0.061 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0045597 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0045597 Census Yes 97 0.159 327 47 0.144 0
KDF1 KDF1 Q8NAX2 Keratinocyte differentiation factor 1 chr1 GO:0045597 Not Cancer Driver No 61 0.153 277 50 0.181 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0045597 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0045597 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0045597 Census, Compendium Yes 226 0.232 83 33 0.398 21
KITLG KITLG P21583 Kit ligand chr12 GO:0045597 Not Cancer Driver No 48 0.176 61 9 0.148 1
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:0045597 Not Cancer Driver No 59 0.123 349 46 0.132 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0045597 Compendium Yes 77 0.168 366 40 0.109 0
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0045597 Not Cancer Driver No 228 0.181 442 75 0.17 54
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0045597 Census Yes 64 0.16 370 57 0.154 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0045597 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0045597 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0045597 Not Cancer Driver No 54 0.152 65 16 0.246 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0045597 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0045597 Not Cancer Driver No 148 0.248 235 50 0.213 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0045597 Not Cancer Driver No 162 0.362 277 115 0.415 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0045597 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0045597 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0045597 Not Cancer Driver No 55 0.161 8 0 0.0 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0045597 Not Cancer Driver No 30 0.207 1 0 0.0 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0045597 Not Cancer Driver No 99 0.177 456 84 0.184 1
LOXL2 LOXL2 Q9Y4K0 Lysyl oxidase homolog 2 chr8 GO:0045597 Not Cancer Driver No 134 0.173 39 4 0.103 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0045597 Not Cancer Driver No 65 0.184 9 0 0.0 0
LPL LPL P06858 Lipoprotein lipase chr8 GO:0045597 Not Cancer Driver No 94 0.198 23 3 0.13 70
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0045597 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP3 LRP3 O75074 Low-density lipoprotein receptor-related protein 3 chr19 GO:0045597 Not Cancer Driver No 88 0.114 214 20 0.093 0
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0045597 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0045597 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0045597 Not Cancer Driver No 105 0.13 32 3 0.094 0
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0045597 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTBP3 LTBP3 Q9NS15 Latent-transforming growth factor beta-binding protein 3 chr11 GO:0045597 Not Cancer Driver No 108 0.083 356 22 0.062 0
LTF LTF P02788 Lactotransferrin chr3 GO:0045597 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0045597 Census Yes 95 0.186 84 12 0.143 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0045597 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0045597 Not Cancer Driver No 118 0.188 65 7 0.108 1
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0045597 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0045597 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAMSTR MAMSTR Q6ZN01 MEF2-activating motif and SAP domain-containing transcriptional regulator chr19 GO:0045597 Not Cancer Driver No 32 0.077 404 32 0.079 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0045597 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0045597 Census Yes 157 0.163 593 91 0.153 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0045597 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAPK11 MAPK11 Q15759 Mitogen-activated protein kinase 11 chr22 GO:0045597 Not Cancer Driver No 23 0.063 64 2 0.031 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0045597 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0045597 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0045597 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0045597 Not Cancer Driver No 128 0.169 750 126 0.168 18
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0045597 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0045597 Census, Compendium Yes 56 0.114 297 37 0.125 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0045597 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEDAG MEDAG Q5VYS4 Mesenteric estrogen-dependent adipogenesis protein chr13 GO:0045597 Not Cancer Driver No 46 0.152 1 0 0.0 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0045597 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0045597 Not Cancer Driver No 363 0.128 476 59 0.124 3
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0045597 Not Cancer Driver No 8 0.03 247 7 0.028 0
METRNL METRNL Q641Q3 Meteorin-like protein chr17 GO:0045597 Not Cancer Driver No 26 0.084 88 5 0.057 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0045597 Not Cancer Driver No 64 0.11 118 11 0.093 1
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0045597 Not Cancer Driver No 44 0.153 136 21 0.154 0
MPL MPL P40238 Thrombopoietin receptor chr1 GO:0045597 Census Yes 77 0.121 129 19 0.147 14
MSR1 MSR1 P21757 Macrophage scavenger receptor types I and II chr8 GO:0045597 Not Cancer Driver No 167 0.37 241 106 0.44 0
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0045597 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTCH2 MTCH2 Q9Y6C9 Mitochondrial carrier homolog 2 chr11 GO:0045597 Not Cancer Driver No 45 0.149 11 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0045597 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTURN MTURN Q8N3F0 Maturin chr7 GO:0045597 Not Cancer Driver No 15 0.115 27 6 0.222 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0045597 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0045597 Census Yes 82 0.128 528 69 0.131 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0045597 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0045597 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0045597 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0045597 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYOC MYOC Q99972 Myocilin chr1 GO:0045597 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0045597 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0045597 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0045597 Not Cancer Driver No 36 0.161 132 20 0.152 0
NAPEPLD NAPEPLD Q6IQ20 N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D chr7 GO:0045597 Not Cancer Driver No 55 0.14 76 7 0.092 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0045597 Not Cancer Driver No 247 0.219 51 10 0.196 4
NCOA3 NCOA3 Q9Y6Q9 Nuclear receptor coactivator 3 chr20 GO:0045597 Not Cancer Driver No 176 0.124 1231 160 0.13 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0045597 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0045597 Not Cancer Driver No 106 0.127 516 72 0.14 0
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 GO:0045597 Not Cancer Driver No 238 0.294 7 3 0.429 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0045597 Not Cancer Driver No 62 0.108 153 11 0.072 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0045597 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD4 NEUROD4 Q9HD90 Neurogenic differentiation factor 4 chr12 GO:0045597 Not Cancer Driver No 123 0.372 236 83 0.352 0
NF2 NF2 P35240 Merlin chr22 GO:0045597 Census, Compendium Yes 69 0.116 252 26 0.103 16
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0045597 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBID NFKBID Q8NI38 NF-kappa-B inhibitor delta chr19 GO:0045597 Not Cancer Driver No 47 0.15 124 20 0.161 0
NFKBIZ NFKBIZ Q9BYH8 NF-kappa-B inhibitor zeta chr3 GO:0045597 Not Cancer Driver No 96 0.134 443 53 0.12 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0045597 Not Cancer Driver No 66 0.274 93 25 0.269 1
NKAP NKAP Q8N5F7 NF-kappa-B-activating protein chrX GO:0045597 Not Cancer Driver No 80 0.193 409 77 0.188 3
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0045597 Not Cancer Driver No 84 0.308 206 65 0.316 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0045597 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0045597 Not Cancer Driver No 38 0.104 325 34 0.105 0
NKX6-2 NKX6-2 Q9C056 Homeobox protein Nkx-6.2 chr10 GO:0045597 Not Cancer Driver No 27 0.097 137 23 0.168 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0045597 Not Cancer Driver No 339 0.327 64 33 0.516 37
NME2 NME2 P22392 Nucleoside diphosphate kinase B chr17 GO:0045597 Not Cancer Driver No 13 0.086 11 1 0.091 0
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0045597 Not Cancer Driver No 33 0.077 89 3 0.034 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0045597 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0045597 Census, Compendium Yes 282 0.114 630 77 0.122 1
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0045597 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0045597 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0045597 Not Cancer Driver No 47 0.118 118 9 0.076 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0045597 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0045597 Compendium Yes 146 0.158 211 31 0.147 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0045597 Not Cancer Driver No 57 0.094 66 4 0.061 2
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0045597 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0045597 Census, Compendium Yes 234 0.111 1864 203 0.109 0
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0045597 Not Cancer Driver No 233 0.123 553 60 0.108 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0045597 Not Cancer Driver No 22 0.039 52 6 0.115 0
OLFM1 OLFM1 Q99784 Noelin chr9 GO:0045597 Not Cancer Driver No 88 0.181 83 10 0.12 0
OLFM2 OLFM2 O95897 Noelin-2 chr19 GO:0045597 Not Cancer Driver No 74 0.163 16 2 0.125 0
OLFM4 OLFM4 Q6UX06 Olfactomedin-4 chr13 GO:0045597 Not Cancer Driver No 117 0.229 54 11 0.204 0
OLIG2_ENST00000382357 OLIG2 Q13516 Oligodendrocyte transcription factor 2 chr21 GO:0045597 Census Yes 37 0.115 256 37 0.145 0
OTP OTP Q5XKR4 Homeobox protein orthopedia chr5 GO:0045597 Not Cancer Driver No 36 0.111 278 29 0.104 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0045597 Not Cancer Driver No 29 0.105 139 8 0.058 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0045597 Not Cancer Driver No 61 0.12 79 15 0.19 1
PA2G4 PA2G4 Q9UQ80 Proliferation-associated protein 2G4 chr12 GO:0045597 Not Cancer Driver No 45 0.114 128 18 0.141 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0045597 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0045597 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0045597 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP2 PARP2 Q9UGN5 Poly [ADP-ribose] polymerase 2 chr14 GO:0045597 Not Cancer Driver No 74 0.127 172 23 0.134 0
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 GO:0045597 Not Cancer Driver No 87 0.138 67 13 0.194 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0045597 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0045597 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0045597 Census Yes 84 0.187 291 55 0.189 4
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0045597 Not Cancer Driver No 46 0.115 13 5 0.385 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0045597 Not Cancer Driver No 142 0.228 110 28 0.255 1
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0045597 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE5A PDE5A O76074 cGMP-specific 3',5'-cyclic phosphodiesterase chr4 GO:0045597 Not Cancer Driver No 113 0.129 163 23 0.141 0
PDLIM7 PDLIM7 Q9NR12 PDZ and LIM domain protein 7 chr5 GO:0045597 Not Cancer Driver No 48 0.105 244 20 0.082 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0045597 Not Cancer Driver No 37 0.228 96 24 0.25 0
PF4 PF4 P02776 Platelet factor 4 chr4 GO:0045597 Not Cancer Driver No 13 0.129 0 0 0.0 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0045597 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0045597 Census, Compendium Yes 71 0.227 27 8 0.296 0
PITHD1 PITHD1 Q9GZP4 PITH domain-containing protein 1 chr1 GO:0045597 Not Cancer Driver No 26 0.123 119 11 0.092 0
PKDCC PKDCC Q504Y2 Extracellular tyrosine-protein kinase PKDCC chr2 GO:0045597 Not Cancer Driver No 36 0.073 124 0 0.0 0
PLA2G10 PLA2G10 O15496 Group 10 secretory phospholipase A2 chr16 GO:0045597 Not Cancer Driver No 5 0.03 0 0 0.0 0
PLA2G2A_ENST00000375111 PLA2G2A P14555 Phospholipase A2, membrane associated chr1 GO:0045597 Not Cancer Driver No 25 0.174 0 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0045597 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0045597 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLAG1_ENST00000429357 PLAG1 Q6DJT9 Zinc finger protein PLAG1 chr8 GO:0045597 Census, Compendium Yes 108 0.216 209 48 0.23 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0045597 Not Cancer Driver No 313 0.257 481 104 0.216 0
PNP PNP P00491 Purine nucleoside phosphorylase chr14 GO:0045597 Not Cancer Driver No 38 0.131 29 2 0.069 5
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0045597 Not Cancer Driver No 62 0.092 93 4 0.043 9
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0045597 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0045597 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0045597 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0045597 Census Yes 72 0.143 44 4 0.091 3
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0045597 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0045597 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 GO:0045597 Not Cancer Driver No 117 0.141 657 90 0.137 0
PPP2R3C PPP2R3C Q969Q6 Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma chr14 GO:0045597 Not Cancer Driver No 44 0.097 30 3 0.1 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0045597 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0045597 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0045597 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0045597 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0045597 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0045597 Census Yes 201 0.22 189 33 0.175 2
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0045597 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0045597 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0045597 Not Cancer Driver No 83 0.13 72 6 0.083 0
PROC PROC P04070 Vitamin K-dependent protein C chr2 GO:0045597 Not Cancer Driver No 73 0.158 41 9 0.22 36
PROM1 PROM1 O43490 Prominin-1 chr4 GO:0045597 Not Cancer Driver No 94 0.109 76 9 0.118 3
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0045597 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0045597 Not Cancer Driver No 71 0.141 109 16 0.147 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0045597 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTCH2 PTCH2 Q9Y6C5 Protein patched homolog 2 chr1 GO:0045597 Not Cancer Driver No 159 0.132 130 15 0.115 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0045597 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTN PTN P21246 Pleiotrophin chr7 GO:0045597 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0045597 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0045597 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0045597 Not Cancer Driver No 480 0.207 978 216 0.221 0
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0045597 Not Cancer Driver No 51 0.102 186 22 0.118 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0045597 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0045597 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0045597 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0045597 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAMP2 RAMP2 O60895 Receptor activity-modifying protein 2 chr17 GO:0045597 Not Cancer Driver No 18 0.103 34 6 0.176 0
RANBP3L_ENST00000296604 RANBP3L Q86VV4 Ran-binding protein 3-like chr5 GO:0045597 Not Cancer Driver No 71 0.153 185 33 0.178 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0045597 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0045597 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0045597 Census, Compendium Yes 70 0.152 167 14 0.084 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0045597 Not Cancer Driver No 16 0.098 14 2 0.143 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0045597 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0045597 Not Cancer Driver No 96 0.12 191 12 0.063 1
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0045597 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0045597 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0045597 Not Cancer Driver No 40 0.11 129 12 0.093 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:0045597 Not Cancer Driver No 47 0.097 324 28 0.086 0
RELN RELN P78509 Reelin chr7 GO:0045597 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0045597 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFX3_ENST00000617270 RFX3 P48380 Transcription factor RFX3 chr9 GO:0045597 Not Cancer Driver No 113 0.151 308 41 0.133 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0045597 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHEB RHEB Q15382 GTP-binding protein Rheb chr7 GO:0045597 Not Cancer Driver No 30 0.163 0 0 0.0 0
RHEX RHEX Q6ZWK4 Regulator of hemoglobinization and erythroid cell expansion protein chr1 GO:0045597 Not Cancer Driver No 35 0.203 116 27 0.233 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0045597 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0045597 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0045597 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0045597 Not Cancer Driver No 131 0.123 421 76 0.181 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0045597 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0045597 Not Cancer Driver No 86 0.136 168 26 0.155 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0045597 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0045597 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0045597 Compendium Yes 106 0.143 145 18 0.124 13
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0045597 Not Cancer Driver No 25 0.115 71 6 0.085 0
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0045597 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0045597 Not Cancer Driver No 75 0.16 204 29 0.142 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0045597 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0045597 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0045597 Not Cancer Driver No 59 0.142 331 45 0.136 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0045597 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0045597 Not Cancer Driver No 38 0.108 16 3 0.188 2
SART1 SART1 O43290 U4/U6.U5 tri-snRNP-associated protein 1 chr11 GO:0045597 Not Cancer Driver No 71 0.089 685 63 0.092 0
SASH3 SASH3 O75995 SAM and SH3 domain-containing protein 3 chrX GO:0045597 Not Cancer Driver No 59 0.155 327 49 0.15 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 GO:0045597 Not Cancer Driver No 42 0.11 243 17 0.07 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0045597 Not Cancer Driver No 100 0.14 170 35 0.206 0
SCUBE3 SCUBE3 Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 chr6 GO:0045597 Not Cancer Driver No 131 0.132 110 17 0.155 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0045597 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0045597 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0045597 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0045597 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0045597 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0045597 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0045597 Not Cancer Driver No 62 0.156 0 0 0.0 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0045597 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETD3 SETD3 Q86TU7 Actin-histidine N-methyltransferase chr14 GO:0045597 Not Cancer Driver No 73 0.123 140 24 0.171 0
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0045597 Not Cancer Driver No 27 0.109 75 9 0.12 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0045597 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0045597 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0045597 Census Yes 81 0.234 68 22 0.324 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0045597 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0045597 Not Cancer Driver No 67 0.202 200 40 0.2 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0045597 Census Yes 68 0.108 470 52 0.111 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0045597 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0045597 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0045597 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC6A6_ENST00000622186 SLC6A6 P31641 Sodium- and chloride-dependent taurine transporter chr3 GO:0045597 Not Cancer Driver No 80 0.129 22 1 0.045 2
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0045597 Not Cancer Driver No 68 0.127 80 16 0.2 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0045597 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0045597 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0045597 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0045597 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0045597 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0045597 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAP1 SMAP1 Q8IYB5 Stromal membrane-associated protein 1 chr6 GO:0045597 Not Cancer Driver No 54 0.116 352 46 0.131 0
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0045597 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0045597 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMYD1 SMYD1 Q8NB12 Histone-lysine N-methyltransferase SMYD1 chr2 GO:0045597 Not Cancer Driver No 116 0.237 31 9 0.29 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0045597 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0045597 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0045597 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS3 SOCS3 O14543 Suppressor of cytokine signaling 3 chr17 GO:0045597 Not Cancer Driver No 27 0.12 111 14 0.126 0
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0045597 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0045597 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0045597 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0045597 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX12 SOX12 O15370 Transcription factor SOX-12 chr20 GO:0045597 Not Cancer Driver No 20 0.063 307 19 0.062 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0045597 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0045597 Compendium Yes 81 0.196 378 59 0.156 2
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0045597 Census Yes 39 0.123 312 39 0.125 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0045597 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX5 SOX5 P35711 Transcription factor SOX-5 chr12 GO:0045597 Not Cancer Driver No 182 0.239 665 162 0.244 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 GO:0045597 Not Cancer Driver No 130 0.157 744 118 0.159 0
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0045597 Not Cancer Driver No 43 0.096 403 39 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0045597 Compendium Yes 86 0.169 495 82 0.166 18
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 GO:0045597 Not Cancer Driver No 63 0.146 332 44 0.133 0
SPDEF SPDEF O95238 SAM pointed domain-containing Ets transcription factor chr6 GO:0045597 Not Cancer Driver No 47 0.14 110 24 0.218 0
SPINT1 SPINT1 O43278 Kunitz-type protease inhibitor 1 chr15 GO:0045597 Not Cancer Driver No 63 0.119 75 12 0.16 0
SRF SRF P11831 Serum response factor chr6 GO:0045597 Not Cancer Driver No 44 0.087 443 42 0.095 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0045597 Census Yes 53 0.134 356 48 0.135 0
SS18L2 SS18L2 Q9UHA2 SS18-like protein 2 chr3 GO:0045597 Not Cancer Driver No 4 0.052 7 1 0.143 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0045597 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0045597 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0045597 Census, Compendium Yes 93 0.118 144 19 0.132 5
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0045597 Not Cancer Driver No 68 0.119 486 54 0.111 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0045597 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0045597 Not Cancer Driver No 70 0.144 231 30 0.13 0
SUCO_ENST00000263688 SUCO Q9UBS9 SUN domain-containing ossification factor chr1 GO:0045597 Not Cancer Driver No 164 0.131 785 99 0.126 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0045597 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2B1 SULT2B1 O00204 Sulfotransferase 2B1 chr19 GO:0045597 Not Cancer Driver No 42 0.115 100 11 0.11 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0045597 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0045597 Census Yes 96 0.151 131 27 0.206 5
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0045597 Not Cancer Driver No 208 0.132 584 76 0.13 3
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0045597 Not Cancer Driver No 22 0.068 27 1 0.037 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0045597 Census Yes 54 0.163 305 53 0.174 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0045597 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0045597 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0045597 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0045597 Not Cancer Driver No 155 0.299 351 113 0.322 5
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0045597 Not Cancer Driver No 19 0.095 134 4 0.03 0
TENM4 TENM4 Q6N022 Teneurin-4 chr11 GO:0045597 Not Cancer Driver No 492 0.178 498 63 0.127 3
TENT5A TENT5A Q96IP4 Terminal nucleotidyltransferase 5A chr6 GO:0045597 Not Cancer Driver No 43 0.097 0 0 0.0 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0045597 Census Yes 110 0.097 212 16 0.075 31
TESC TESC Q96BS2 Calcineurin B homologous protein 3 chr12 GO:0045597 Not Cancer Driver No 31 0.145 73 6 0.082 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0045597 Not Cancer Driver No 63 0.101 339 35 0.103 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0045597 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFE3 TFE3 P19532 Transcription factor E3 chrX GO:0045597 Census Yes 92 0.16 524 84 0.16 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0045597 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0045597 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0045597 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0045597 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0045597 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0045597 Census, Compendium Yes 106 0.187 60 16 0.267 25
THPO THPO P40225 Thrombopoietin chr3 GO:0045597 Not Cancer Driver No 63 0.178 163 25 0.153 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0045597 Not Cancer Driver No 370 0.233 810 194 0.24 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0045597 Not Cancer Driver No 108 0.138 0 0 0.0 0
TMEM100 TMEM100 Q9NV29 Transmembrane protein 100 chr17 GO:0045597 Not Cancer Driver No 29 0.216 0 0 0.0 0
TMEM119 TMEM119 Q4V9L6 Transmembrane protein 119 chr12 GO:0045597 Not Cancer Driver No 59 0.208 195 47 0.241 0
TMEM64 TMEM64 Q6YI46 Transmembrane protein 64 chr8 GO:0045597 Not Cancer Driver No 33 0.087 32 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0045597 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0045597 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0045597 Not Cancer Driver No 52 0.164 56 1 0.018 1
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0045597 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0045597 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNFSF9 TNFSF9 P41273 Tumor necrosis factor ligand superfamily member 9 chr19 GO:0045597 Not Cancer Driver No 32 0.126 39 4 0.103 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0045597 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0045597 Census, Compendium Yes 229 0.337 398 143 0.359 28
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0045597 Not Cancer Driver No 82 0.129 443 55 0.124 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0045597 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0045597 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0045597 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0045597 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0045597 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0045597 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0045597 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0045597 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0045597 Not Cancer Driver No 105 0.137 175 23 0.131 0
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0045597 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0045597 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0045597 Not Cancer Driver No 34 0.097 59 8 0.136 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0045597 Not Cancer Driver No 23 0.114 132 11 0.083 7
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0045597 Not Cancer Driver No 24 0.212 28 8 0.286 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0045597 Not Cancer Driver No 109 0.137 141 24 0.17 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0045597 Not Cancer Driver No 120 0.11 248 30 0.121 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0045597 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0045597 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0045597 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEZF1 VEZF1 Q14119 Vascular endothelial zinc finger 1 chr17 GO:0045597 Not Cancer Driver No 56 0.107 332 32 0.096 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0045597 Census, Compendium Yes 142 0.667 117 36 0.308 133
VNN1 VNN1 O95497 Pantetheinase chr6 GO:0045597 Not Cancer Driver No 88 0.172 20 5 0.25 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0045597 Not Cancer Driver No 52 0.167 135 19 0.141 0
VSTM2A_ENST00000407838 VSTM2A Q8TAG5 V-set and transmembrane domain-containing protein 2A chr7 GO:0045597 Not Cancer Driver No 87 0.369 121 42 0.347 0
WDFY2 WDFY2 Q96P53 WD repeat and FYVE domain-containing protein 2 chr13 GO:0045597 Not Cancer Driver No 49 0.122 20 2 0.1 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0045597 Not Cancer Driver No 181 0.119 792 100 0.126 5
WDR63 DNAI3 Q8IWG1 Dynein axonemal intermediate chain 3 chr1 GO:0045597 Not Cancer Driver No 129 0.145 210 31 0.148 0
WIF1 WIF1 Q9Y5W5 Wnt inhibitory factor 1 chr12 GO:0045597 Census Yes 74 0.195 30 3 0.1 0
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0045597 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0045597 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0045597 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0045597 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0045597 Not Cancer Driver No 55 0.158 11 1 0.091 0
WWTR1_ENST00000360632 WWTR1 Q9GZV5 WW domain-containing transcription regulator protein 1 chr3 GO:0045597 Census Yes 41 0.102 387 41 0.106 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0045597 Not Cancer Driver No 19 0.073 169 9 0.053 0
XKR8 XKR8 Q9H6D3 XK-related protein 8 chr1 GO:0045597 Not Cancer Driver No 34 0.086 4 0 0.0 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0045597 Not Cancer Driver No 66 0.108 140 12 0.086 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0045597 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0045597 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBED2 ZBED2 Q9BTP6 Zinc finger BED domain-containing protein 2 chr3 GO:0045597 Not Cancer Driver No 62 0.284 172 39 0.227 0
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0045597 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0045597 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZBTB46_ENST00000302995 ZBTB46 Q86UZ6 Zinc finger and BTB domain-containing protein 46 chr20 GO:0045597 Not Cancer Driver No 115 0.195 301 68 0.226 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0045597 Compendium Yes 103 0.191 353 70 0.198 0
ZBTB7C_ENST00000590800 ZBTB7C A1YPR0 Zinc finger and BTB domain-containing protein 7C chr18 GO:0045597 Not Cancer Driver No 91 0.147 249 40 0.161 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0045597 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0045597 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0045597 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0045597 Compendium Yes 57 0.169 212 30 0.142 0
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0045597 Not Cancer Driver No 45 0.109 140 22 0.157 1
ZHX3_ENST00000559234 ZHX3 Q9H4I2 Zinc fingers and homeoboxes protein 3 chr20 GO:0045597 Not Cancer Driver No 111 0.116 617 73 0.118 0
ZNF16 ZNF16 P17020 Zinc finger protein 16 chr8 GO:0045597 Not Cancer Driver No 99 0.145 293 40 0.137 0
ZNF219 ZNF219 Q9P2Y4 Zinc finger protein 219 chr14 GO:0045597 Not Cancer Driver No 44 0.061 628 37 0.059 0
ZNF268_ENST00000228289 ZNF268 Q14587 Zinc finger protein 268 chr12 GO:0045597 Not Cancer Driver No 96 0.101 63 9 0.143 0
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0045597 Not Cancer Driver No 185 0.138 942 133 0.141 1
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0045597 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0045597 Not Cancer Driver No 26 0.044 415 14 0.034 0