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Total number of protein in "GO:0044089" GO term:  409

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0044089 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0044089 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0044089 Not Cancer Driver No 56 0.109 361 38 0.105 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0044089 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0044089 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0044089 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACTR3 ACTR3 P61158 Actin-related protein 3 chr2 GO:0044089 Not Cancer Driver No 32 0.077 16 2 0.125 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0044089 Compendium Yes 213 0.134 485 47 0.097 0
ADGRB3_ENST00000546190 ADGRB3 O60242 Adhesion G protein-coupled receptor B3 chr6 GO:0044089 Not Cancer Driver No 558 0.367 336 149 0.443 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0044089 Not Cancer Driver No 130 0.118 615 66 0.107 0
AGRN AGRN O00468 Agrin chr1 GO:0044089 Not Cancer Driver No 188 0.091 490 40 0.082 5
AGT AGT P01019 Angiotensinogen chr1 GO:0044089 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0044089 Census Yes 474 0.121 2281 268 0.117 1
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0044089 Not Cancer Driver No 11 0.057 125 9 0.072 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0044089 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0044089 Not Cancer Driver No 46 0.093 85 7 0.082 0
AMIGO2_ENST00000429635 AMIGO2 Q86SJ2 Amphoterin-induced protein 2 chr12 GO:0044089 Not Cancer Driver No 81 0.155 44 6 0.136 0
AMIGO3 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 GO:0044089 Not Cancer Driver No 69 0.137 60 7 0.117 0
ANKRD53 ANKRD53 Q8N9V6 Ankyrin repeat domain-containing protein 53 chr2 GO:0044089 Not Cancer Driver No 57 0.108 252 21 0.083 0
ANLN ANLN Q9NQW6 Anillin chr7 GO:0044089 Not Cancer Driver No 144 0.128 767 104 0.136 2
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0044089 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0044089 Not Cancer Driver No 28 0.105 131 8 0.061 3
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 GO:0044089 Not Cancer Driver No 152 0.105 401 28 0.07 0
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0044089 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0044089 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0044089 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0044089 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0044089 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0044089 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL3 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0044089 Not Cancer Driver No 16 0.088 0 0 0.0 2
ARPC2_ENST00000315717 ARPC2 O15144 Actin-related protein 2/3 complex subunit 2 chr2 GO:0044089 Not Cancer Driver No 40 0.133 49 8 0.163 0
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 GO:0044089 Not Cancer Driver No 183 0.162 584 108 0.185 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0044089 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATAT1_ENST00000376485 ATAT1 Q5SQI0 Alpha-tubulin N-acetyltransferase 1 chr6 GO:0044089 Not Cancer Driver No 31 0.074 271 20 0.074 0
ATF7IP2_ENST00000356427 ATF7IP2 Q5U623 Activating transcription factor 7-interacting protein 2 chr16 GO:0044089 Not Cancer Driver No 89 0.13 456 66 0.145 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0044089 Compendium Yes 160 0.126 1136 139 0.122 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 GO:0044089 Not Cancer Driver No 228 0.118 887 124 0.14 0
ATMIN ATMIN O43313 ATM interactor chr16 GO:0044089 Not Cancer Driver No 85 0.103 466 40 0.086 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0044089 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0044089 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0044089 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0044089 Census, Compendium Yes 338 0.128 106 14 0.132 1
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0044089 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AVIL AVIL O75366 Advillin chr12 GO:0044089 Not Cancer Driver No 91 0.111 138 17 0.123 2
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0044089 Not Cancer Driver No 55 0.12 402 49 0.122 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0044089 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0044089 Not Cancer Driver No 134 0.144 417 67 0.161 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0044089 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0044089 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0044089 Not Cancer Driver No 88 0.161 267 38 0.142 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0044089 Not Cancer Driver No 91 0.211 69 18 0.261 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 GO:0044089 Not Cancer Driver No 7 0.093 14 1 0.071 0
C15orf62 C15orf62 A8K5M9 Uncharacterized protein C15orf62, mitochondrial chr15 GO:0044089 Not Cancer Driver No 6 0.034 126 4 0.032 0
CALY CALY Q9NYX4 Neuron-specific vesicular protein calcyon chr10 GO:0044089 Not Cancer Driver No 8 0.037 133 5 0.038 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0044089 Not Cancer Driver No 45 0.129 95 7 0.074 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0044089 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0044089 Not Cancer Driver No 154 0.107 669 75 0.112 4
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0044089 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0044089 Not Cancer Driver No 27 0.179 0 0 0.0 25
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0044089 Not Cancer Driver No 46 0.238 14 2 0.143 0
CBLN2 CBLN2 Q8IUK8 Cerebellin-2 chr18 GO:0044089 Not Cancer Driver No 78 0.348 35 8 0.229 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0044089 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0044089 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0044089 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0044089 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCP110 CCP110 O43303 Centriolar coiled-coil protein of 110 kDa chr16 GO:0044089 Not Cancer Driver No 94 0.093 679 61 0.09 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0044089 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0044089 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0044089 Not Cancer Driver No 37 0.115 0 0 0.0 0
CDC34 CDC34 P49427 Ubiquitin-conjugating enzyme E2 R1 chr19 GO:0044089 Not Cancer Driver No 26 0.11 95 11 0.116 0
CDC42EP1 CDC42EP1 Q00587 Cdc42 effector protein 1 chr22 GO:0044089 Not Cancer Driver No 52 0.133 371 47 0.127 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0044089 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42EP3 CDC42EP3 Q9UKI2 Cdc42 effector protein 3 chr2 GO:0044089 Not Cancer Driver No 35 0.138 192 22 0.115 0
CDC42EP4 CDC42EP4 Q9H3Q1 Cdc42 effector protein 4 chr17 GO:0044089 Not Cancer Driver No 47 0.132 352 47 0.134 0
CDC42EP5 CDC42EP5 Q6NZY7 Cdc42 effector protein 5 chr19 GO:0044089 Not Cancer Driver No 4 0.027 147 4 0.027 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0044089 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDH17 CDH17 Q12864 Cadherin-17 chr8 GO:0044089 Census Yes 166 0.2 186 35 0.188 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0044089 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0044089 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0044089 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0044089 Census, Compendium Yes 19 0.096 198 19 0.096 0
CENPJ CENPJ Q9HC77 Centromere protein J chr13 GO:0044089 Not Cancer Driver No 176 0.132 1176 158 0.134 1
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 GO:0044089 Not Cancer Driver No 102 0.103 448 52 0.116 1
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 GO:0044089 Not Cancer Driver No 127 0.111 690 72 0.104 0
CEP295 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 GO:0044089 Not Cancer Driver No 115 0.044 2026 87 0.043 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0044089 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHMP2A_ENST00000601220 CHMP2A O43633 Charged multivesicular body protein 2a chr19 GO:0044089 Not Cancer Driver No 29 0.131 161 22 0.137 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0044089 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0044089 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0044089 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0044089 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN19 CLDN19 Q8N6F1 Claudin-19 chr1 GO:0044089 Not Cancer Driver No 27 0.121 20 2 0.1 3
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0044089 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0044089 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0044089 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CLRN1_ENST00000327047 CLRN1 P58418 Clarin-1 chr3 GO:0044089 Not Cancer Driver No 49 0.211 0 0 0.0 8
CLSTN1 CLSTN1 O94985 Calsyntenin-1 chr1 GO:0044089 Not Cancer Driver No 110 0.112 271 22 0.081 0
CLSTN2 CLSTN2 Q9H4D0 Calsyntenin-2 chr3 GO:0044089 Not Cancer Driver No 232 0.243 177 41 0.232 0
CLSTN3 CLSTN3 Q9BQT9 Calsyntenin-3 chr12 GO:0044089 Not Cancer Driver No 140 0.146 211 27 0.128 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0044089 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0044089 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0044089 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0044089 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0044089 Not Cancer Driver No 65 0.117 66 4 0.061 0
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0044089 Census Yes 570 0.428 161 82 0.509 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 GO:0044089 Not Cancer Driver No 233 0.185 1149 216 0.188 0
COL16A1 COL16A1 Q07092 Collagen alpha-1(XVI) chain chr1 GO:0044089 Not Cancer Driver No 192 0.12 1381 163 0.118 0
CRB3_ENST00000598494 CRB3 Q9BUF7 Protein crumbs homolog 3 chr19 GO:0044089 Not Cancer Driver No 12 0.1 53 7 0.132 0
CROCC CROCC Q5TZA2 Rootletin chr1 GO:0044089 Not Cancer Driver No 254 0.126 1583 184 0.116 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0044089 Not Cancer Driver No 11 0.076 34 3 0.088 0
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0044089 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0044089 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0044089 Not Cancer Driver No 11 0.101 0 0 0.0 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0044089 Not Cancer Driver No 46 0.037 96 0 0.0 0
DAG1_ENST00000515359 DAG1 Q14118 Dystroglycan 1 chr3 GO:0044089 Not Cancer Driver No 102 0.114 485 61 0.126 4
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0044089 Census Yes 172 0.135 817 111 0.136 11
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0044089 Census, Compendium Yes 133 0.201 301 47 0.156 18
DEF8 DEF8 Q6ZN54 Differentially expressed in FDCP 8 homolog chr16 GO:0044089 Not Cancer Driver No 58 0.113 123 23 0.187 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0044089 Not Cancer Driver No 53 0.075 125 12 0.096 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0044089 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0044089 Census Yes 138 0.159 270 43 0.159 22
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 GO:0044089 Not Cancer Driver No 166 0.191 257 45 0.175 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0044089 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0044089 Not Cancer Driver No 312 0.151 240 29 0.121 0
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0044089 Not Cancer Driver No 93 0.163 128 14 0.109 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 GO:0044089 Not Cancer Driver No 35 0.095 31 0 0.0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0044089 Not Cancer Driver No 505 0.109 495 62 0.125 21
DZIP1_ENST00000376829 DZIP1 Q86YF9 Cilium assembly protein DZIP1 chr13 GO:0044089 Not Cancer Driver No 143 0.165 523 92 0.176 2
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0044089 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0044089 Not Cancer Driver No 34 0.149 25 6 0.24 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0044089 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EMILIN1 EMILIN1 Q9Y6C2 EMILIN-1 chr2 GO:0044089 Not Cancer Driver No 125 0.123 669 69 0.103 0
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 GO:0044089 Not Cancer Driver No 64 0.147 267 38 0.142 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0044089 Not Cancer Driver No 97 0.132 312 45 0.144 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0044089 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0044089 Compendium Yes 171 0.175 187 39 0.209 3
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0044089 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0044089 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0044089 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPS8L1 EPS8L1 Q8TE68 Epidermal growth factor receptor kinase substrate 8-like protein 1 chr19 GO:0044089 Not Cancer Driver No 116 0.16 521 96 0.184 0
EPS8L2_ENST00000530636 EPS8L2 Q9H6S3 Epidermal growth factor receptor kinase substrate 8-like protein 2 chr11 GO:0044089 Not Cancer Driver No 68 0.095 372 31 0.083 0
EPS8L3_ENST00000361965 EPS8L3 Q8TE67 Epidermal growth factor receptor kinase substrate 8-like protein 3 chr1 GO:0044089 Not Cancer Driver No 105 0.177 338 57 0.169 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0044089 Not Cancer Driver No 106 0.129 459 54 0.118 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0044089 Not Cancer Driver No 42 0.141 105 14 0.133 1
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 GO:0044089 Not Cancer Driver No 42 0.101 335 37 0.11 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0044089 Not Cancer Driver No 55 0.139 7 2 0.286 0
FAM208A_ENST00000355628 TASOR Q9UK61 Protein TASOR chr3 GO:0044089 Not Cancer Driver No 150 0.09 776 68 0.088 0
FAM98A FAM98A Q8NCA5 Protein FAM98A chr2 GO:0044089 Not Cancer Driver No 63 0.122 314 36 0.115 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0044089 Not Cancer Driver No 100 0.148 65 8 0.123 2
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0044089 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0044089 Census Yes 103 0.125 245 34 0.139 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0044089 Not Cancer Driver No 151 0.13 575 82 0.143 0
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0044089 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLRT2_ENST00000554746 FLRT2 O43155 Leucine-rich repeat transmembrane protein FLRT2 chr14 GO:0044089 Not Cancer Driver No 225 0.341 80 21 0.263 0
FLRT3_ENST00000341420 FLRT3 Q9NZU0 Leucine-rich repeat transmembrane protein FLRT3 chr20 GO:0044089 Not Cancer Driver No 108 0.166 112 15 0.134 4
FMN1 FMN1 Q68DA7 Formin-1 chr15 GO:0044089 Not Cancer Driver No 117 0.082 983 67 0.068 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0044089 Not Cancer Driver No 124 0.196 327 70 0.214 3
FNBP1L FNBP1L Q5T0N5 Formin-binding protein 1-like chr1 GO:0044089 Not Cancer Driver No 56 0.093 371 30 0.081 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0044089 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0044089 Not Cancer Driver No 58 0.118 81 5 0.062 0
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0044089 Not Cancer Driver No 38 0.091 43 4 0.093 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0044089 Not Cancer Driver No 85 0.182 352 65 0.185 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 GO:0044089 Not Cancer Driver No 64 0.133 384 53 0.138 0
GBP5 GBP5 Q96PP8 Guanylate-binding protein 5 chr1 GO:0044089 Not Cancer Driver No 106 0.181 170 21 0.124 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0044089 Not Cancer Driver No 20 0.171 52 11 0.212 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0044089 Not Cancer Driver No 67 0.088 434 42 0.097 0
GPM6A_ENST00000393658 GPM6A P51674 Neuronal membrane glycoprotein M6-a chr4 GO:0044089 Not Cancer Driver No 83 0.299 15 5 0.333 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0044089 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0044089 Not Cancer Driver No 79 0.115 240 21 0.087 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0044089 Not Cancer Driver No 350 0.348 155 35 0.226 3
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0044089 Not Cancer Driver No 56 0.133 146 13 0.089 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0044089 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAS3 HAS3 O00219 Hyaluronan synthase 3 chr16 GO:0044089 Not Cancer Driver No 63 0.114 13 0 0.0 0
HGS HGS O14964 Hepatocyte growth factor-regulated tyrosine kinase substrate chr17 GO:0044089 Not Cancer Driver No 109 0.14 528 74 0.14 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0044089 Not Cancer Driver No 94 0.088 524 34 0.065 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0044089 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0044089 Not Cancer Driver No 121 0.23 277 75 0.271 2
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0044089 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0044089 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0044089 Not Cancer Driver No 15 0.023 200 5 0.025 0
HTT HTT P42858 Huntingtin chr4 GO:0044089 Not Cancer Driver No 336 0.107 666 69 0.104 2
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0044089 Not Cancer Driver No 47 0.108 9 0 0.0 1
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0044089 Not Cancer Driver No 20 0.129 17 6 0.353 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0044089 Not Cancer Driver No 51 0.307 23 6 0.261 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0044089 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0044089 Not Cancer Driver No 205 0.295 77 19 0.247 0
IL1RAP_ENST00000447382 IL1RAP Q9NPH3 Interleukin-1 receptor accessory protein chr3 GO:0044089 Not Cancer Driver No 79 0.139 50 11 0.22 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0044089 Not Cancer Driver No 13 0.097 0 0 0.0 0
IRX3 IRX3 P78415 Iroquois-class homeodomain protein IRX-3 chr16 GO:0044089 Not Cancer Driver No 38 0.076 407 32 0.079 0
ISG15 ISG15 P05161 Ubiquitin-like protein ISG15 chr1 GO:0044089 Not Cancer Driver No 12 0.073 24 2 0.083 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0044089 Not Cancer Driver No 26 0.13 58 11 0.19 0
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 GO:0044089 Not Cancer Driver No 23 0.072 187 14 0.075 1
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0044089 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIAA1211 CRACD Q6ZU35 Capping protein-inhibiting regulator of actin dynamics chr4 GO:0044089 Not Cancer Driver No 245 0.199 1210 241 0.199 0
KIAA1324 ELAPOR1 Q6UXG2 Endosome/lysosome-associated apoptosis and autophagy regulator 1 chr1 GO:0044089 Not Cancer Driver No 94 0.093 56 5 0.089 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0044089 Census, Compendium Yes 226 0.232 83 33 0.398 21
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0044089 Census Yes 99 0.158 73 11 0.151 0
LDB2 LDB2 O43679 LIM domain-binding protein 2 chr4 GO:0044089 Not Cancer Driver No 122 0.327 145 54 0.372 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0044089 Not Cancer Driver No 177 0.163 880 140 0.159 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0044089 Not Cancer Driver No 110 0.17 170 30 0.176 0
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0044089 Not Cancer Driver No 34 0.105 0 0 0.0 0
LINGO2_ENST00000308675 LINGO2 Q7L985 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 chr9 GO:0044089 Not Cancer Driver No 214 0.353 30 8 0.267 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0044089 Not Cancer Driver No 79 0.217 21 6 0.286 0
LRRC24 LRRC24 Q50LG9 Leucine-rich repeat-containing protein 24 chr8 GO:0044089 Not Cancer Driver No 32 0.062 131 13 0.099 0
LRRC4B_ENST00000389201 LRRC4B Q9NT99 Leucine-rich repeat-containing protein 4B chr19 GO:0044089 Not Cancer Driver No 141 0.198 245 46 0.188 0
LRRN1 LRRN1 Q6UXK5 Leucine-rich repeat neuronal protein 1 chr3 GO:0044089 Not Cancer Driver No 140 0.196 18 5 0.278 0
LRRN3_ENST00000422987 LRRN3 Q9H3W5 Leucine-rich repeat neuronal protein 3 chr7 GO:0044089 Not Cancer Driver No 156 0.22 19 4 0.211 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0044089 Not Cancer Driver No 172 0.33 57 17 0.298 0
LRRTM2 LRRTM2 O43300 Leucine-rich repeat transmembrane neuronal protein 2 chr5 GO:0044089 Not Cancer Driver No 57 0.11 33 1 0.03 0
LRRTM3 LRRTM3 Q86VH5 Leucine-rich repeat transmembrane neuronal protein 3 chr10 GO:0044089 Not Cancer Driver No 142 0.244 136 31 0.228 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0044089 Not Cancer Driver No 86 0.119 240 30 0.125 1
LRTM2_ENST00000299194 LRTM2 Q8N967 Leucine-rich repeat and transmembrane domain-containing protein 2 chr12 GO:0044089 Not Cancer Driver No 81 0.219 77 19 0.247 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0044089 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0044089 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0044089 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0044089 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0044089 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0044089 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 GO:0044089 Not Cancer Driver No 94 0.125 403 46 0.114 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0044089 Not Cancer Driver No 75 0.154 483 74 0.153 46
MED25 MED25 Q71SY5 Mediator of RNA polymerase II transcription subunit 25 chr19 GO:0044089 Not Cancer Driver No 103 0.138 432 54 0.125 2
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0044089 Census, Compendium Yes 226 0.163 62 15 0.242 19
MIEN1_ENST00000394231 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0044089 Not Cancer Driver No 17 0.148 37 4 0.108 0
MNS1 MNS1 Q8NEH6 Meiosis-specific nuclear structural protein 1 chr15 GO:0044089 Not Cancer Driver No 47 0.095 327 32 0.098 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0044089 Not Cancer Driver No 48 0.137 47 8 0.17 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 GO:0044089 Not Cancer Driver No 125 0.121 523 69 0.132 16
MPHOSPH8 MPHOSPH8 Q99549 M-phase phosphoprotein 8 chr13 GO:0044089 Not Cancer Driver No 105 0.122 523 66 0.126 0
MSN MSN P26038 Moesin chrX GO:0044089 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0044089 Not Cancer Driver No 68 0.181 64 11 0.172 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0044089 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0044089 Not Cancer Driver No 107 0.142 584 86 0.147 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0044089 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYOC MYOC Q99972 Myocilin chr1 GO:0044089 Not Cancer Driver No 92 0.183 196 43 0.219 58
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0044089 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0044089 Not Cancer Driver No 129 0.114 44 3 0.068 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0044089 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0044089 Not Cancer Driver No 35 0.116 23 0 0.0 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0044089 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF2 NF2 P35240 Merlin chr22 GO:0044089 Census, Compendium Yes 69 0.116 252 26 0.103 16
NIN NIN Q8N4C6 Ninein chr14 GO:0044089 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0044089 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0044089 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0044089 Not Cancer Driver No 158 0.186 257 54 0.21 2
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 GO:0044089 Not Cancer Driver No 108 0.148 259 32 0.124 1
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 GO:0044089 Not Cancer Driver No 176 0.123 469 54 0.115 17
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0044089 Not Cancer Driver No 56 0.122 179 30 0.168 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0044089 Compendium Yes 146 0.158 211 31 0.147 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0044089 Not Cancer Driver No 593 0.401 301 110 0.365 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0044089 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0044089 Not Cancer Driver No 155 0.189 117 18 0.154 1
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0044089 Census, Compendium Yes 234 0.111 1864 203 0.109 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0044089 Not Cancer Driver No 76 0.146 377 56 0.149 1
OCLN OCLN Q16625 Occludin chr5 GO:0044089 Not Cancer Driver No 54 0.103 244 21 0.086 1
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0044089 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0044089 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0044089 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0044089 Not Cancer Driver No 57 0.167 21 2 0.095 3
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0044089 Not Cancer Driver No 57 0.105 299 30 0.1 2
PALM PALM O75781 Paralemmin-1 chr19 GO:0044089 Not Cancer Driver No 50 0.129 381 50 0.131 0
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0044089 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0044089 Not Cancer Driver No 104 0.117 323 35 0.108 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0044089 Not Cancer Driver No 85 0.098 272 22 0.081 0
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0044089 Not Cancer Driver No 16 0.114 7 1 0.143 3
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0044089 Not Cancer Driver No 20 0.143 0 0 0.0 0
PFN3 PFN3 P60673 Profilin-3 chr5 GO:0044089 Not Cancer Driver No 8 0.058 0 0 0.0 0
PHLDB1 PHLDB1 Q86UU1 Pleckstrin homology-like domain family B member 1 chr11 GO:0044089 Not Cancer Driver No 160 0.116 1071 130 0.121 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0044089 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0044089 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0044089 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0044089 Census, Compendium Yes 154 0.213 268 61 0.228 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0044089 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0044089 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0044089 Not Cancer Driver No 62 0.147 111 23 0.207 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0044089 Not Cancer Driver No 367 0.159 780 107 0.137 1
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0044089 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0044089 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEK2 PLEK2 Q9NYT0 Pleckstrin-2 chr14 GO:0044089 Not Cancer Driver No 41 0.116 25 5 0.2 0
PLEKHM1 PLEKHM1 Q9Y4G2 Pleckstrin homology domain-containing family M member 1 chr17 GO:0044089 Not Cancer Driver No 140 0.133 373 55 0.147 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 GO:0044089 Not Cancer Driver No 102 0.105 451 45 0.1 0
PLPPR5 PLPPR5 Q32ZL2 Phospholipid phosphatase-related protein type 5 chr1 GO:0044089 Not Cancer Driver No 74 0.231 0 0 0.0 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0044089 Not Cancer Driver No 36 0.098 94 13 0.138 0
PPHLN1_ENST00000610488 PPHLN1 Q8NEY8 Periphilin-1 chr12 GO:0044089 Not Cancer Driver No 64 0.14 447 62 0.139 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 GO:0044089 Not Cancer Driver No 114 0.151 384 53 0.138 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0044089 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R35 PPP1R35 Q8TAP8 Protein phosphatase 1 regulatory subunit 35 chr7 GO:0044089 Not Cancer Driver No 19 0.075 207 15 0.072 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0044089 Not Cancer Driver No 94 0.14 154 22 0.143 0
PSMC5 PSMC5 P62195 26S proteasome regulatory subunit 8 chr17 GO:0044089 Not Cancer Driver No 52 0.128 64 6 0.094 0
PSMC6_ENST00000606149 PSMC6 P62333 26S proteasome regulatory subunit 10B chr14 GO:0044089 Not Cancer Driver No 49 0.126 69 8 0.116 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0044089 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0044089 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0044089 Not Cancer Driver No 184 0.138 401 61 0.152 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0044089 Not Cancer Driver No 62 0.105 341 24 0.07 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0044089 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0044089 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0044089 Not Cancer Driver No 27 0.13 11 0 0.0 4
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0044089 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0044089 Not Cancer Driver No 31 0.161 0 0 0.0 2
RALA RALA P11233 Ras-related protein Ral-A chr7 GO:0044089 Not Cancer Driver No 34 0.165 34 3 0.088 5
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0044089 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0044089 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0044089 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0044089 Not Cancer Driver No 73 0.076 505 48 0.095 0
RESF1 RESF1 Q9HCM1 Retroelement silencing factor 1 chr12 GO:0044089 Not Cancer Driver No 217 0.124 1528 185 0.121 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0044089 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0044089 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0044089 Not Cancer Driver No 30 0.155 53 7 0.132 0
RHOQ RHOQ P17081 Rho-related GTP-binding protein RhoQ chr2 GO:0044089 Not Cancer Driver No 25 0.122 0 0 0.0 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0044089 Not Cancer Driver No 131 0.123 421 76 0.181 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0044089 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0044089 Not Cancer Driver No 145 0.104 732 81 0.111 0
RP1 RP1 P56715 Oxygen-regulated protein 1 chr8 GO:0044089 Not Cancer Driver No 737 0.342 1215 441 0.363 6
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0044089 Not Cancer Driver No 22 0.091 48 4 0.083 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0044089 Not Cancer Driver No 11 0.113 3 1 0.333 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 GO:0044089 Not Cancer Driver No 82 0.125 331 37 0.112 1
SAXO1 SAXO1 Q8IYX7 Stabilizer of axonemal microtubules 1 chr9 GO:0044089 Not Cancer Driver No 63 0.133 249 35 0.141 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0044089 Not Cancer Driver No 31 0.1 259 30 0.116 0
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0044089 Census, Compendium Yes 34 0.172 110 25 0.227 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0044089 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0044089 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0044089 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEPT7_ENST00000350320 SEPTIN7 Q16181 Septin-7 chr7 GO:0044089 Not Cancer Driver No 49 0.112 200 21 0.105 0
SEPT9 SEPTIN9 Q9UHD8 Septin-9 chr17 GO:0044089 Not Cancer Driver No 84 0.143 332 50 0.151 2
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0044089 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 GO:0044089 Census, Compendium Yes 184 0.143 597 77 0.129 0
SETDB2 SETDB2 Q96T68 Histone-lysine N-methyltransferase SETDB2 chr13 GO:0044089 Not Cancer Driver No 70 0.097 253 26 0.103 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0044089 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0044089 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0044089 Compendium Yes 172 0.135 617 73 0.118 0
SKAP1_ENST00000584924 SKAP1 Q86WV1 Src kinase-associated phosphoprotein 1 chr17 GO:0044089 Not Cancer Driver No 67 0.187 130 27 0.208 0
SLAIN1_ENST00000466548 SLAIN1 Q8ND83 SLAIN motif-containing protein 1 chr13 GO:0044089 Not Cancer Driver No 62 0.109 485 58 0.12 0
SLAIN2 SLAIN2 Q9P270 SLAIN motif-containing protein 2 chr4 GO:0044089 Not Cancer Driver No 62 0.107 562 60 0.107 0
SLITRK1 SLITRK1 Q96PX8 SLIT and NTRK-like protein 1 chr13 GO:0044089 Not Cancer Driver No 299 0.43 126 64 0.508 0
SLITRK2 SLITRK2 Q9H156 SLIT and NTRK-like protein 2 chrX GO:0044089 Not Cancer Driver No 276 0.327 244 91 0.373 0
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 GO:0044089 Not Cancer Driver No 335 0.343 321 127 0.396 0
SLITRK4_ENST00000338017 SLITRK4 Q8IW52 SLIT and NTRK-like protein 4 chrX GO:0044089 Not Cancer Driver No 257 0.307 172 45 0.262 0
SLITRK5 SLITRK5 O94991 SLIT and NTRK-like protein 5 chr13 GO:0044089 Not Cancer Driver No 257 0.268 346 93 0.269 0
SLITRK6_ENST00000643778 SLITRK6 Q9H5Y7 SLIT and NTRK-like protein 6 chr13 GO:0044089 Not Cancer Driver No 244 0.29 225 53 0.236 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0044089 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0044089 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0044089 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0044089 Not Cancer Driver No 92 0.14 224 29 0.129 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0044089 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNF8 SNF8 Q96H20 Vacuolar-sorting protein SNF8 chr17 GO:0044089 Not Cancer Driver No 30 0.116 10 2 0.2 0
SNX18 SNX18 Q96RF0 Sorting nexin-18 chr5 GO:0044089 Not Cancer Driver No 54 0.086 236 7 0.03 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 GO:0044089 Not Cancer Driver No 36 0.082 98 4 0.041 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0044089 Not Cancer Driver No 31 0.069 101 5 0.05 0
SORBS3 SORBS3 O60504 Vinexin chr8 GO:0044089 Not Cancer Driver No 62 0.092 577 56 0.097 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0044089 Compendium Yes 86 0.169 495 82 0.166 18
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 GO:0044089 Not Cancer Driver No 136 0.114 636 83 0.131 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0044089 Census Yes 53 0.099 130 11 0.085 1
SRF SRF P11831 Serum response factor chr6 GO:0044089 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0044089 Not Cancer Driver No 86 0.185 64 13 0.203 0
ST8SIA2 ST8SIA2 Q92186 Alpha-2,8-sialyltransferase 8B chr15 GO:0044089 Not Cancer Driver No 84 0.224 38 8 0.211 0
STAM STAM Q92783 Signal transducing adapter molecule 1 chr10 GO:0044089 Not Cancer Driver No 73 0.135 361 40 0.111 0
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0044089 Not Cancer Driver No 68 0.119 486 54 0.111 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 GO:0044089 Census, Compendium Yes 147 0.114 735 85 0.116 1
STMP1 STMP1 E0CX11 Short transmembrane mitochondrial protein 1 chr7 GO:0044089 Not Cancer Driver No 1 0.021 12 0 0.0 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0044089 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX18 STX18 Q9P2W9 Syntaxin-18 chr4 GO:0044089 Not Cancer Driver No 28 0.084 174 15 0.086 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0044089 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYNDIG1 SYNDIG1 Q9H7V2 Synapse differentiation-inducing gene protein 1 chr20 GO:0044089 Not Cancer Driver No 90 0.349 110 40 0.364 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 GO:0044089 Not Cancer Driver No 103 0.111 918 102 0.111 0
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0044089 Not Cancer Driver No 103 0.105 950 99 0.104 0
SYNPO2_ENST00000429713 SYNPO2 Q9UMS6 Synaptopodin-2 chr4 GO:0044089 Not Cancer Driver No 240 0.22 978 219 0.224 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0044089 Not Cancer Driver No 69 0.17 28 2 0.071 0
TAPT1 TAPT1 Q6NXT6 Transmembrane anterior posterior transformation protein 1 homolog chr4 GO:0044089 Not Cancer Driver No 47 0.083 131 12 0.092 1
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0044089 Not Cancer Driver No 155 0.299 351 113 0.322 5
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0044089 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0044089 Not Cancer Driver No 728 0.267 482 164 0.34 0
TENM2_ENST00000518659 TENM2 Q9NT68 Teneurin-2 chr5 GO:0044089 Not Cancer Driver No 524 0.189 521 92 0.177 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0044089 Not Cancer Driver No 63 0.144 220 34 0.155 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0044089 Not Cancer Driver No 63 0.101 339 35 0.103 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0044089 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0044089 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0044089 Not Cancer Driver No 86 0.171 23 3 0.13 15
THBS2 THBS2 P35442 Thrombospondin-2 chr6 GO:0044089 Not Cancer Driver No 246 0.21 319 68 0.213 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0044089 Not Cancer Driver No 24 0.149 5 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0044089 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0044089 Not Cancer Driver No 99 0.124 1 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0044089 Not Cancer Driver No 24 0.103 45 3 0.067 0
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 GO:0044089 Not Cancer Driver No 230 0.134 703 101 0.144 3
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0044089 Not Cancer Driver No 58 0.138 13 1 0.077 0
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0044089 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0044089 Census Yes 311 0.132 1990 266 0.134 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0044089 Not Cancer Driver No 87 0.104 430 41 0.095 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0044089 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSG101 TSG101 Q99816 Tumor susceptibility gene 101 protein chr11 GO:0044089 Not Cancer Driver No 46 0.118 159 23 0.145 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0044089 Not Cancer Driver No 34 0.097 59 8 0.136 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0044089 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0044089 Not Cancer Driver No 214 0.135 448 77 0.172 0
USP50 USP50 Q70EL3 Inactive ubiquitin carboxyl-terminal hydrolase 50 chr15 GO:0044089 Not Cancer Driver No 33 0.097 2 0 0.0 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0044089 Not Cancer Driver No 27 0.116 41 7 0.171 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0044089 Not Cancer Driver No 124 0.15 222 38 0.171 0
VPS4A VPS4A Q9UN37 Vacuolar protein sorting-associated protein 4A chr16 GO:0044089 Not Cancer Driver No 48 0.11 167 17 0.102 4
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0044089 Not Cancer Driver No 52 0.117 195 22 0.113 0
VSTM5 VSTM5 A8MXK1 V-set and transmembrane domain-containing protein 5 chr11 GO:0044089 Not Cancer Driver No 8 0.04 7 1 0.143 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0044089 Not Cancer Driver No 61 0.122 400 43 0.107 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0044089 Not Cancer Driver No 6 0.013 336 6 0.018 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 GO:0044089 Not Cancer Driver No 90 0.068 1204 89 0.074 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0044089 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR45_ENST00000634944 WDR45 Q9Y484 WD repeat domain phosphoinositide-interacting protein 4 chrX GO:0044089 Compendium Yes 62 0.172 10 1 0.1 0
WIPI1 WIPI1 Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 chr17 GO:0044089 Not Cancer Driver No 45 0.101 113 9 0.08 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0044089 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0044089 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0044089 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0044089 Not Cancer Driver No 93 0.266 18 9 0.5 4
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 GO:0044089 Not Cancer Driver No 50 0.109 5 0 0.0 0
ZMYND10 ZMYND10 O75800 Zinc finger MYND domain-containing protein 10 chr3 GO:0044089 Not Cancer Driver No 40 0.091 38 6 0.158 5
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0044089 Not Cancer Driver No 126 0.191 54 12 0.222 0