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Total number of protein in "GO:0043565" GO term:  405

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0043565 Not Cancer Driver No 129 0.152 351 75 0.214 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0043565 Not Cancer Driver No 34 0.107 103 14 0.136 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0043565 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0043565 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0043565 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 GO:0043565 Not Cancer Driver No 79 0.124 264 38 0.144 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0043565 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASCL2 ASCL2 Q99929 Achaete-scute homolog 2 chr11 GO:0043565 Not Cancer Driver No 2 0.01 166 1 0.006 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0043565 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0043565 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF5_ENST00000595125 ATF5 Q9Y2D1 Cyclic AMP-dependent transcription factor ATF-5 chr19 GO:0043565 Not Cancer Driver No 47 0.167 239 40 0.167 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0043565 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0043565 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0043565 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0043565 Not Cancer Driver No 31 0.097 254 23 0.091 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0043565 Not Cancer Driver No 28 0.224 119 25 0.21 0
BAZ2A BAZ2A Q9UIF9 Bromodomain adjacent to zinc finger domain protein 2A chr12 GO:0043565 Not Cancer Driver No 186 0.098 1283 118 0.092 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0043565 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0043565 Census, Compendium Yes 134 0.19 328 67 0.204 0
BEND3_ENST00000369042 BEND3 Q5T5X7 BEN domain-containing protein 3 chr6 GO:0043565 Not Cancer Driver No 104 0.126 311 44 0.141 0
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0043565 Not Cancer Driver No 52 0.126 242 31 0.128 0
BHLHE41 BHLHE41 Q9C0J9 Class E basic helix-loop-helix protein 41 chr12 GO:0043565 Not Cancer Driver No 21 0.044 213 10 0.047 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0043565 Census Yes 153 0.108 667 70 0.105 8
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0043565 Not Cancer Driver No 195 0.196 530 111 0.209 0
BNC2 BNC2 Q6ZN30 Zinc finger protein basonuclin-2 chr9 GO:0043565 Not Cancer Driver No 242 0.22 682 150 0.22 1
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 GO:0043565 Not Cancer Driver No 309 0.101 2187 218 0.1 2
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0043565 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRF2 BRF2 Q9HAW0 Transcription factor IIIB 50 kDa subunit chr8 GO:0043565 Not Cancer Driver No 40 0.095 138 13 0.094 0
CALCOCO1 CALCOCO1 Q9P1Z2 Calcium-binding and coiled-coil domain-containing protein 1 chr12 GO:0043565 Not Cancer Driver No 88 0.127 486 59 0.121 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0043565 Census, Compendium Yes 300 0.179 883 152 0.172 0
CAMTA2_ENST00000348066 CAMTA2 O94983 Calmodulin-binding transcription activator 2 chr17 GO:0043565 Not Cancer Driver No 148 0.123 613 84 0.137 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0043565 Census, Compendium Yes 39 0.214 94 17 0.181 0
CDX1 CDX1 P47902 Homeobox protein CDX-1 chr5 GO:0043565 Not Cancer Driver No 21 0.079 241 13 0.054 0
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 GO:0043565 Census, Compendium Yes 39 0.125 271 35 0.129 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0043565 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEBPG_ENST00000585933 CEBPG P53567 CCAAT/enhancer-binding protein gamma chr19 GO:0043565 Not Cancer Driver No 13 0.087 141 12 0.085 0
CENPB CENPB P07199 Major centromere autoantigen B chr20 GO:0043565 Not Cancer Driver No 64 0.107 374 39 0.104 0
CENPC CENPC Q03188 Centromere protein C chr4 GO:0043565 Not Cancer Driver No 96 0.102 790 84 0.106 0
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 GO:0043565 Not Cancer Driver No 24 0.159 114 21 0.184 1
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0043565 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIART CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0043565 Not Cancer Driver No 59 0.153 272 40 0.147 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0043565 Not Cancer Driver No 83 0.098 458 38 0.083 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0043565 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0043565 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0043565 Census Yes 68 0.131 372 50 0.134 0
CREB3L2 CREB3L2 Q70SY1 Cyclic AMP-responsive element-binding protein 3-like protein 2 chr7 GO:0043565 Census Yes 61 0.117 364 46 0.126 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0043565 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREB3L4_ENST00000271889 CREB3L4 Q8TEY5 Cyclic AMP-responsive element-binding protein 3-like protein 4 chr1 GO:0043565 Not Cancer Driver No 55 0.139 241 27 0.112 0
CREB5 CREB5 Q02930 Cyclic AMP-responsive element-binding protein 5 chr7 GO:0043565 Not Cancer Driver No 92 0.181 494 89 0.18 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0043565 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSRNP1 CSRNP1 Q96S65 Cysteine/serine-rich nuclear protein 1 chr3 GO:0043565 Not Cancer Driver No 71 0.121 312 33 0.106 0
CSRNP2 CSRNP2 Q9H175 Cysteine/serine-rich nuclear protein 2 chr12 GO:0043565 Not Cancer Driver No 64 0.118 319 38 0.119 0
CSRNP3_ENST00000342316 CSRNP3 Q8WYN3 Cysteine/serine-rich nuclear protein 3 chr2 GO:0043565 Not Cancer Driver No 113 0.193 395 71 0.18 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0043565 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTCF CTCF P49711 Transcriptional repressor CTCF chr16 GO:0043565 Census, Compendium Yes 151 0.208 481 83 0.173 1
CTCFL_ENST00000371196 CTCFL Q8NI51 Transcriptional repressor CTCFL chr20 GO:0043565 Not Cancer Driver No 136 0.205 266 61 0.229 0
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0043565 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CXXC1_ENST00000285106 CXXC1 Q9P0U4 CXXC-type zinc finger protein 1 chr18 GO:0043565 Not Cancer Driver No 115 0.175 366 65 0.178 0
CXXC5_ENST00000511048 CXXC5 Q7LFL8 CXXC-type zinc finger protein 5 chr5 GO:0043565 Not Cancer Driver No 34 0.106 196 20 0.102 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0043565 Not Cancer Driver No 53 0.075 125 12 0.096 0
DLX4 DLX4 Q92988 Homeobox protein DLX-4 chr17 GO:0043565 Not Cancer Driver No 34 0.142 179 26 0.145 0
DMBX1_ENST00000371956 DMBX1 Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 chr1 GO:0043565 Not Cancer Driver No 93 0.243 272 69 0.254 0
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0043565 Not Cancer Driver No 203 0.126 702 78 0.111 4
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0043565 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F2 E2F2 Q14209 Transcription factor E2F2 chr1 GO:0043565 Not Cancer Driver No 42 0.096 282 28 0.099 0
E2F3 E2F3 O00716 Transcription factor E2F3 chr6 GO:0043565 Not Cancer Driver No 46 0.099 253 20 0.079 0
E4F1 E4F1 Q66K89 Transcription factor E4F1 chr16 GO:0043565 Not Cancer Driver No 84 0.107 462 46 0.1 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0043565 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0043565 Compendium Yes 90 0.189 352 59 0.168 11
EGR4 EGR4 Q05215 Early growth response protein 4 chr2 GO:0043565 Not Cancer Driver No 56 0.095 377 27 0.072 0
ELK3 ELK3 P41970 ETS domain-containing protein Elk-3 chr12 GO:0043565 Not Cancer Driver No 58 0.143 163 16 0.098 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0043565 Not Cancer Driver No 82 0.12 436 50 0.115 0
EPAS1 EPAS1 Q99814 Endothelial PAS domain-containing protein 1 chr2 GO:0043565 Census, Compendium Yes 120 0.138 449 53 0.118 6
ERF ERF P50548 ETS domain-containing transcription factor ERF chr19 GO:0043565 Not Cancer Driver No 74 0.135 398 54 0.136 3
ERH ERH P84090 Enhancer of rudimentary homolog chr14 GO:0043565 Not Cancer Driver No 7 0.067 11 0 0.0 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0043565 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0043565 Not Cancer Driver No 90 0.17 92 11 0.12 1
ESRRA_ENST00000000442 ESRRA P11474 Steroid hormone receptor ERR1 chr11 GO:0043565 Compendium Yes 37 0.087 101 9 0.089 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0043565 Not Cancer Driver No 90 0.208 35 7 0.2 4
ESRRG_ENST00000408911 ESRRG P62508 Estrogen-related receptor gamma chr1 GO:0043565 Not Cancer Driver No 135 0.295 76 29 0.382 0
ESX1 ESX1 Q8N693 Homeobox protein ESX1 chrX GO:0043565 Not Cancer Driver No 107 0.264 363 96 0.264 0
ETV3L ETV3L Q6ZN32 ETS translocation variant 3-like protein chr1 GO:0043565 Not Cancer Driver No 70 0.194 125 21 0.168 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0043565 Census, Compendium Yes 120 0.161 284 44 0.155 11
FBXL19 FBXL19 Q6PCT2 F-box/LRR-repeat protein 19 chr16 GO:0043565 Not Cancer Driver No 67 0.097 350 38 0.109 0
FIGLA FIGLA Q6QHK4 Factor in the germline alpha chr2 GO:0043565 Not Cancer Driver No 22 0.1 154 17 0.11 0
FOS FOS P01100 Protein c-Fos chr14 GO:0043565 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0043565 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0043565 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0043565 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0043565 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXD2 FOXD2 O60548 Forkhead box protein D2 chr1 GO:0043565 Not Cancer Driver No 25 0.051 330 12 0.036 0
FOXD4 FOXD4 Q12950 Forkhead box protein D4 chr9 GO:0043565 Not Cancer Driver No 77 0.175 327 55 0.168 0
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0043565 Not Cancer Driver No 38 0.102 133 5 0.038 4
FOXE3 FOXE3 Q13461 Forkhead box protein E3 chr1 GO:0043565 Not Cancer Driver No 12 0.038 186 4 0.022 6
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0043565 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXF2 FOXF2 Q12947 Forkhead box protein F2 chr6 GO:0043565 Not Cancer Driver No 44 0.099 277 10 0.036 0
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0043565 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXI1 FOXI1 Q12951 Forkhead box protein I1 chr5 GO:0043565 Not Cancer Driver No 91 0.241 253 66 0.261 0
FOXJ3 FOXJ3 Q9UPW0 Forkhead box protein J3 chr1 GO:0043565 Not Cancer Driver No 77 0.124 459 54 0.118 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0043565 Not Cancer Driver No 79 0.12 548 64 0.117 0
FOXL1 FOXL1 Q12952 Forkhead box protein L1 chr16 GO:0043565 Not Cancer Driver No 62 0.18 212 26 0.123 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0043565 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0043565 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0043565 Census Yes 75 0.149 441 61 0.138 0
FOXP2_ENST00000350908 FOXP2 O15409 Forkhead box protein P2 chr7 GO:0043565 Not Cancer Driver No 156 0.218 444 100 0.225 1
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0043565 Not Cancer Driver No 38 0.088 186 16 0.086 10
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0043565 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0043565 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0043565 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATAD1 GATAD1 Q8WUU5 GATA zinc finger domain-containing protein 1 chr7 GO:0043565 Not Cancer Driver No 14 0.052 131 4 0.031 1
GATAD2A_ENST00000360315 GATAD2A Q86YP4 Transcriptional repressor p66-alpha chr19 GO:0043565 Not Cancer Driver No 88 0.139 548 77 0.141 0
GATAD2B_ENST00000634544 GATAD2B Q8WXI9 Transcriptional repressor p66-beta chr1 GO:0043565 Not Cancer Driver No 76 0.128 510 67 0.131 0
GBX2 GBX2 P52951 Homeobox protein GBX-2 chr2 GO:0043565 Not Cancer Driver No 43 0.124 243 31 0.128 0
GCM2 GCM2 O75603 Chorion-specific transcription factor GCMb chr6 GO:0043565 Not Cancer Driver No 91 0.18 272 50 0.184 7
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0043565 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GOLGB1_ENST00000340645 GOLGB1 Q14789 Golgin subfamily B member 1 chr3 GO:0043565 Not Cancer Driver No 403 0.124 2416 300 0.124 0
GRHL1 GRHL1 Q9NZI5 Grainyhead-like protein 1 homolog chr2 GO:0043565 Not Cancer Driver No 99 0.16 256 36 0.141 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0043565 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 GO:0043565 Not Cancer Driver No 83 0.133 291 38 0.131 3
GSC2 GSC2 O15499 Homeobox protein goosecoid-2 chr22 GO:0043565 Not Cancer Driver No 10 0.049 115 8 0.07 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 GO:0043565 Not Cancer Driver No 26 0.098 137 14 0.102 0
GTF2A1 GTF2A1 P52655 Transcription initiation factor IIA subunit 1 chr14 GO:0043565 Not Cancer Driver No 49 0.13 260 38 0.146 0
GTF2B GTF2B Q00403 Transcription initiation factor IIB chr1 GO:0043565 Not Cancer Driver No 33 0.104 80 6 0.075 0
GZF1 GZF1 Q9H116 GDNF-inducible zinc finger protein 1 chr20 GO:0043565 Not Cancer Driver No 94 0.132 312 47 0.151 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0043565 Not Cancer Driver No 46 0.124 125 19 0.152 0
H2AFZ H2AZ1 P0C0S5 Histone H2A.Z chr4 GO:0043565 Not Cancer Driver No 23 0.18 71 16 0.225 0
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0043565 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0043565 Not Cancer Driver No 28 0.206 51 14 0.275 3
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0043565 Not Cancer Driver No 47 0.217 124 29 0.234 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0043565 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0043565 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0043565 Not Cancer Driver No 182 0.168 749 132 0.176 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0043565 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES3 HES3 Q5TGS1 Transcription factor HES-3 chr1 GO:0043565 Not Cancer Driver No 13 0.07 129 10 0.078 0
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0043565 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHEX HHEX Q03014 Hematopoietically-expressed homeobox protein HHEX chr10 GO:0043565 Not Cancer Driver No 23 0.085 193 21 0.109 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:0043565 Not Cancer Driver No 24 0.033 361 6 0.017 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0043565 Census Yes 118 0.143 435 51 0.117 0
HLF HLF Q16534 Hepatic leukemia factor chr17 GO:0043565 Census Yes 56 0.19 263 51 0.194 0
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0043565 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0043565 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMGA2_ENST00000403681 HMGA2 P52926 High mobility group protein HMGI-C chr12 GO:0043565 Census Yes 12 0.11 109 12 0.11 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0043565 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0043565 Census, Compendium Yes 68 0.193 255 41 0.161 0
HOXA13 HOXA13 P31271 Homeobox protein Hox-A13 chr7 GO:0043565 Census Yes 37 0.095 171 22 0.129 4
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0043565 Not Cancer Driver No 90 0.269 262 68 0.26 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0043565 Not Cancer Driver No 60 0.261 71 15 0.211 0
HOXB13 HOXB13 Q92826 Homeobox protein Hox-B13 chr17 GO:0043565 Not Cancer Driver No 61 0.215 179 37 0.207 1
HOXB2 HOXB2 P14652 Homeobox protein Hox-B2 chr17 GO:0043565 Not Cancer Driver No 47 0.132 269 35 0.13 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0043565 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSF2 HSF2 Q03933 Heat shock factor protein 2 chr6 GO:0043565 Not Cancer Driver No 64 0.119 292 37 0.127 0
IKZF3 IKZF3 Q9UKT9 Zinc finger protein Aiolos chr17 GO:0043565 Census, Compendium Yes 106 0.208 284 60 0.211 1
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0043565 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF4 IRF4 Q15306 Interferon regulatory factor 4 chr6 GO:0043565 Census, Compendium Yes 99 0.22 155 45 0.29 0
IRF5_ENST00000402030 IRF5 Q13568 Interferon regulatory factor 5 chr7 GO:0043565 Not Cancer Driver No 93 0.187 237 64 0.27 0
IRF6 IRF6 O14896 Interferon regulatory factor 6 chr1 GO:0043565 Not Cancer Driver No 97 0.208 173 36 0.208 45
IRX1 IRX1 P78414 Iroquois-class homeodomain protein IRX-1 chr5 GO:0043565 Not Cancer Driver No 161 0.335 335 126 0.376 0
IRX2_ENST00000302057 IRX2 Q9BZI1 Iroquois-class homeodomain protein IRX-2 chr5 GO:0043565 Not Cancer Driver No 88 0.187 323 67 0.207 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0043565 Not Cancer Driver No 16 0.098 142 13 0.092 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0043565 Not Cancer Driver No 67 0.145 19 5 0.263 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0043565 Census Yes 35 0.106 281 25 0.089 0
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:0043565 Not Cancer Driver No 131 0.113 387 48 0.124 0
KDM2B KDM2B Q8NHM5 Lysine-specific demethylase 2B chr12 GO:0043565 Not Cancer Driver No 187 0.14 617 90 0.146 0
KIF2C KIF2C Q99661 Kinesin-like protein KIF2C chr1 GO:0043565 Not Cancer Driver No 110 0.152 337 63 0.187 0
KLF14 KLF14 Q8TD94 Krueppel-like factor 14 chr7 GO:0043565 Not Cancer Driver No 24 0.074 264 20 0.076 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0043565 Census, Compendium Yes 446 0.112 3145 338 0.107 0
KMT2B KMT2B Q9UMN6 Histone-lysine N-methyltransferase 2B chr19 GO:0043565 Compendium Yes 378 0.139 1895 227 0.12 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0043565 Census Yes 64 0.16 370 57 0.154 0
LHX3_ENST00000371748 LHX3 Q9UBR4 LIM/homeobox protein Lhx3 chr9 GO:0043565 Not Cancer Driver No 38 0.096 232 14 0.06 2
LHX4 LHX4 Q969G2 LIM/homeobox protein Lhx4 chr1 GO:0043565 Not Cancer Driver No 75 0.192 219 45 0.205 4
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0043565 Not Cancer Driver No 99 0.103 175 15 0.086 10
LRWD1 LRWD1 Q9UFC0 Leucine-rich repeat and WD repeat-containing protein 1 chr7 GO:0043565 Not Cancer Driver No 75 0.116 133 17 0.128 0
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 GO:0043565 Not Cancer Driver No 126 0.29 114 35 0.307 0
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0043565 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0043565 Census Yes 35 0.108 301 34 0.113 10
MAFF_ENST00000426621 MAFF Q9ULX9 Transcription factor MafF chr22 GO:0043565 Not Cancer Driver No 9 0.055 118 7 0.059 0
MAFK MAFK O60675 Transcription factor MafK chr7 GO:0043565 Not Cancer Driver No 13 0.083 135 12 0.089 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0043565 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAX MAX P61244 Protein max chr14 GO:0043565 Census, Compendium Yes 45 0.281 160 45 0.281 9
MBD1_ENST00000591416 MBD1 Q9UIS9 Methyl-CpG-binding domain protein 1 chr18 GO:0043565 Not Cancer Driver No 115 0.19 322 49 0.152 0
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0043565 Not Cancer Driver No 26 0.063 384 25 0.065 0
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:0043565 Not Cancer Driver No 50 0.172 246 46 0.187 0
MBD4 MBD4 O95243 Methyl-CpG-binding domain protein 4 chr3 GO:0043565 Not Cancer Driver No 61 0.105 268 27 0.101 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0043565 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0043565 Not Cancer Driver No 62 0.122 454 56 0.123 0
MEIS3_ENST00000558555 MEIS3 Q99687 Homeobox protein Meis3 chr19 GO:0043565 Not Cancer Driver No 54 0.144 247 43 0.174 0
MEOX1 MEOX1 P50221 Homeobox protein MOX-1 chr17 GO:0043565 Not Cancer Driver No 46 0.181 236 44 0.186 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 GO:0043565 Not Cancer Driver No 70 0.23 274 63 0.23 0
MITF_ENST00000448226 MITF O75030 Microphthalmia-associated transcription factor chr3 GO:0043565 Census Yes 80 0.152 408 69 0.169 7
MLH3_ENST00000556740 MLH3 Q9UHC1 DNA mismatch repair protein Mlh3 chr14 GO:0043565 Not Cancer Driver No 154 0.106 593 60 0.101 9
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0043565 Not Cancer Driver No 106 0.124 554 66 0.119 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0043565 Not Cancer Driver No 100 0.213 29 5 0.172 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0043565 Census Yes 92 0.099 37 4 0.108 70
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0043565 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTA2 MTA2 O94776 Metastasis-associated protein MTA2 chr11 GO:0043565 Not Cancer Driver No 78 0.117 283 32 0.113 0
MTA3 MTA3 Q9BTC8 Metastasis-associated protein MTA3 chr2 GO:0043565 Not Cancer Driver No 48 0.081 169 18 0.107 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0043565 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0043565 Not Cancer Driver No 11 0.093 11 3 0.273 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0043565 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043565 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0043565 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0043565 Not Cancer Driver No 89 0.368 118 44 0.373 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0043565 Census Yes 45 0.141 246 33 0.134 0
MYOG MYOG P15173 Myogenin chr1 GO:0043565 Not Cancer Driver No 36 0.161 132 20 0.152 0
MYRF MYRF Q9Y2G1 Myelin regulatory factor chr11 GO:0043565 Not Cancer Driver No 103 0.089 684 70 0.102 2
MYRFL MYRFL Q96LU7 Myelin regulatory factor-like protein chr12 GO:0043565 Not Cancer Driver No 8 0.009 316 2 0.006 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0043565 Not Cancer Driver No 25 0.118 125 17 0.136 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0043565 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NEUROD1 NEUROD1 Q13562 Neurogenic differentiation factor 1 chr2 GO:0043565 Not Cancer Driver No 84 0.236 202 52 0.257 2
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0043565 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0043565 Not Cancer Driver No 27 0.114 178 18 0.101 0
NEUROG2 NEUROG2 Q9H2A3 Neurogenin-2 chr4 GO:0043565 Not Cancer Driver No 32 0.118 209 29 0.139 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0043565 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFE2_ENST00000312156 NFE2 Q16621 Transcription factor NF-E2 45 kDa subunit chr12 GO:0043565 Not Cancer Driver No 64 0.172 295 51 0.173 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0043565 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0043565 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX2-8 NKX2-8 O15522 Homeobox protein Nkx-2.8 chr14 GO:0043565 Not Cancer Driver No 18 0.075 162 16 0.099 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0043565 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-3_ENST00000518699 NKX6-3 A6NJ46 Homeobox protein Nkx-6.3 chr8 GO:0043565 Not Cancer Driver No 7 0.026 164 7 0.043 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0043565 Not Cancer Driver No 339 0.327 64 33 0.516 37
NOBOX NOBOX O60393 Homeobox protein NOBOX chr7 GO:0043565 Not Cancer Driver No 127 0.184 615 110 0.179 3
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0043565 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0043565 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0043565 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2C2_ENST00000393102 NR2C2 P49116 Nuclear receptor subfamily 2 group C member 2 chr3 GO:0043565 Not Cancer Driver No 62 0.104 186 24 0.129 0
NR2E3 NR2E3 Q9Y5X4 Photoreceptor-specific nuclear receptor chr15 GO:0043565 Not Cancer Driver No 47 0.115 171 15 0.088 16
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 GO:0043565 Not Cancer Driver No 67 0.158 110 6 0.055 4
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0043565 Not Cancer Driver No 66 0.159 101 1 0.01 5
NR2F6 NR2F6 P10588 Nuclear receptor subfamily 2 group F member 6 chr19 GO:0043565 Not Cancer Driver No 25 0.062 70 4 0.057 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0043565 Census Yes 83 0.133 298 37 0.124 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0043565 Not Cancer Driver No 60 0.13 133 29 0.218 24
NR5A2 NR5A2 O00482 Nuclear receptor subfamily 5 group A member 2 chr1 GO:0043565 Not Cancer Driver No 126 0.233 154 35 0.227 0
NR6A1 NR6A1 Q15406 Nuclear receptor subfamily 6 group A member 1 chr9 GO:0043565 Not Cancer Driver No 43 0.09 124 4 0.032 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0043565 Census, Compendium Yes 191 0.14 552 76 0.138 0
OSR2_ENST00000522510 OSR2 Q8N2R0 Protein odd-skipped-related 2 chr8 GO:0043565 Not Cancer Driver No 59 0.189 66 13 0.197 0
PAX3_ENST00000350526 PAX3 P23760 Paired box protein Pax-3 chr2 GO:0043565 Census Yes 113 0.236 391 95 0.243 28
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0043565 Not Cancer Driver No 72 0.171 337 56 0.166 38
PBX4 PBX4 Q9BYU1 Pre-B-cell leukemia transcription factor 4 chr19 GO:0043565 Not Cancer Driver No 47 0.126 262 26 0.099 0
PCBP1 PCBP1 Q15365 Poly(rC)-binding protein 1 chr2 GO:0043565 Census, Compendium Yes 65 0.183 166 24 0.145 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0043565 Census Yes 160 0.124 948 116 0.122 0
PGBD2 PGBD2 Q6P3X8 PiggyBac transposable element-derived protein 2 chr1 GO:0043565 Not Cancer Driver No 82 0.139 153 19 0.124 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0043565 Not Cancer Driver No 30 0.103 157 13 0.083 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:0043565 Not Cancer Driver No 62 0.125 204 29 0.142 0
POLRMT POLRMT O00411 DNA-directed RNA polymerase, mitochondrial chr19 GO:0043565 Not Cancer Driver No 188 0.153 253 31 0.123 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0043565 Census, Compendium Yes 113 0.178 31 6 0.194 9
POU2F1_ENST00000541643 POU2F1 P14859 POU domain, class 2, transcription factor 1 chr1 GO:0043565 Not Cancer Driver No 95 0.128 433 50 0.115 0
POU2F2 POU2F2 P09086 POU domain, class 2, transcription factor 2 chr19 GO:0043565 Compendium Yes 82 0.171 387 67 0.173 0
POU2F3_ENST00000543440 POU2F3 Q9UKI9 POU domain, class 2, transcription factor 3 chr11 GO:0043565 Not Cancer Driver No 59 0.135 338 52 0.154 0
POU3F1 POU3F1 Q03052 POU domain, class 3, transcription factor 1 chr1 GO:0043565 Not Cancer Driver No 21 0.047 377 7 0.019 0
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0043565 Not Cancer Driver No 43 0.086 402 30 0.075 4
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0043565 Not Cancer Driver No 51 0.122 273 34 0.125 1
POU5F1 POU5F1 Q01860 POU domain, class 5, transcription factor 1 chr6 GO:0043565 Census Yes 36 0.1 186 12 0.065 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0043565 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0043565 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0043565 Not Cancer Driver No 181 0.227 609 148 0.243 0
PRDM16 PRDM16 Q9HAZ2 Histone-lysine N-methyltransferase PRDM16 chr1 GO:0043565 Census Yes 254 0.199 830 152 0.183 1
PRDM2 PRDM2 Q13029 PR domain zinc finger protein 2 chr1 GO:0043565 Census, Compendium Yes 242 0.141 1340 199 0.149 0
PRDM5 PRDM5 Q9NQX1 PR domain zinc finger protein 5 chr4 GO:0043565 Not Cancer Driver No 135 0.214 148 41 0.277 1
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0043565 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0043565 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0043565 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0043565 Not Cancer Driver No 83 0.13 72 6 0.083 0
PTF1A PTF1A Q7RTS3 Pancreas transcription factor 1 subunit alpha chr10 GO:0043565 Not Cancer Driver No 35 0.107 231 31 0.134 0
PURA PURA Q00577 Transcriptional activator protein Pur-alpha chr5 GO:0043565 Not Cancer Driver No 22 0.068 188 10 0.053 6
PURB PURB Q96QR8 Transcriptional activator protein Pur-beta chr7 GO:0043565 Not Cancer Driver No 27 0.087 161 14 0.087 0
PURG PURG Q9UJV8 Purine-rich element-binding protein gamma chr8 GO:0043565 Not Cancer Driver No 69 0.199 174 29 0.167 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0043565 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0043565 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0043565 Not Cancer Driver No 118 0.224 85 23 0.271 6
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0043565 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0043565 Not Cancer Driver No 49 0.098 151 19 0.126 2
RELA RELA Q04206 Transcription factor p65 chr11 GO:0043565 Compendium Yes 75 0.136 400 48 0.12 0
RERE RERE Q9P2R6 Arginine-glutamic acid dipeptide repeats protein chr1 GO:0043565 Not Cancer Driver No 196 0.125 1297 167 0.129 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0043565 Not Cancer Driver No 142 0.129 868 113 0.13 4
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0043565 Not Cancer Driver No 147 0.128 674 82 0.122 0
RFX5_ENST00000452671 RFX5 P48382 DNA-binding protein RFX5 chr1 GO:0043565 Not Cancer Driver No 80 0.13 467 60 0.128 1
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0043565 Not Cancer Driver No 57 0.109 182 17 0.093 4
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0043565 Not Cancer Driver No 51 0.083 98 6 0.061 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0043565 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0043565 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0043565 Not Cancer Driver No 66 0.101 115 15 0.13 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0043565 Not Cancer Driver No 62 0.134 100 13 0.13 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0043565 Compendium Yes 90 0.195 184 26 0.141 0
RXRB_ENST00000374680 RXRB P28702 Retinoic acid receptor RXR-beta chr6 GO:0043565 Not Cancer Driver No 61 0.114 279 25 0.09 0
RXRG RXRG P48443 Retinoic acid receptor RXR-gamma chr1 GO:0043565 Not Cancer Driver No 103 0.222 161 41 0.255 0
SAFB2 SAFB2 Q14151 Scaffold attachment factor B2 chr19 GO:0043565 Not Cancer Driver No 97 0.102 931 88 0.095 0
SAFB_ENST00000292123 SAFB Q15424 Scaffold attachment factor B1 chr19 GO:0043565 Not Cancer Driver No 111 0.121 911 110 0.121 0
SATB1_ENST00000454909 SATB1 Q01826 DNA-binding protein SATB1 chr3 GO:0043565 Compendium Yes 130 0.17 482 84 0.174 12
SCRT1 SCRT1 Q9BWW7 Transcriptional repressor scratch 1 chr8 GO:0043565 Not Cancer Driver No 26 0.075 173 8 0.046 0
SCRT2 SCRT2 Q9NQ03 Transcriptional repressor scratch 2 chr20 GO:0043565 Not Cancer Driver No 19 0.062 168 4 0.024 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0043565 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SHOX SHOX O15266 Short stature homeobox protein chrX GO:0043565 Not Cancer Driver No 78 0.267 169 58 0.343 4
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0043565 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0043565 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLTM SLTM Q9NWH9 SAFB-like transcription modulator chr15 GO:0043565 Not Cancer Driver No 110 0.106 962 103 0.107 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0043565 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0043565 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0043565 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0043565 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0043565 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0043565 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0043565 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNAPC1 SNAPC1 Q16533 snRNA-activating protein complex subunit 1 chr14 GO:0043565 Not Cancer Driver No 36 0.098 158 16 0.101 0
SNAPC3_ENST00000610884 SNAPC3 Q92966 snRNA-activating protein complex subunit 3 chr9 GO:0043565 Not Cancer Driver No 30 0.073 99 2 0.02 0
SOX13 SOX13 Q9UN79 Transcription factor SOX-13 chr1 GO:0043565 Not Cancer Driver No 85 0.137 564 77 0.137 0
SOX14 SOX14 O95416 Transcription factor SOX-14 chr3 GO:0043565 Not Cancer Driver No 48 0.2 128 32 0.25 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0043565 Census Yes 39 0.123 312 39 0.125 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0043565 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0043565 Not Cancer Driver No 96 0.122 599 71 0.119 0
SP4 SP4 Q02446 Transcription factor Sp4 chr7 GO:0043565 Not Cancer Driver No 95 0.121 532 71 0.133 0
SPDEF SPDEF O95238 SAM pointed domain-containing Ets transcription factor chr6 GO:0043565 Not Cancer Driver No 47 0.14 110 24 0.218 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0043565 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0043565 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0043565 Not Cancer Driver No 44 0.087 443 42 0.095 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0043565 Not Cancer Driver No 131 0.175 144 25 0.174 26
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0043565 Not Cancer Driver No 41 0.111 27 2 0.074 2
TAF1B TAF1B Q53T94 TATA box-binding protein-associated factor RNA polymerase I subunit B chr2 GO:0043565 Not Cancer Driver No 61 0.104 54 7 0.13 0
TAF1C TAF1C Q15572 TATA box-binding protein-associated factor RNA polymerase I subunit C chr16 GO:0043565 Not Cancer Driver No 114 0.131 312 35 0.112 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0043565 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0043565 Census Yes 54 0.163 305 53 0.174 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0043565 Not Cancer Driver No 40 0.118 164 14 0.085 0
TBPL1 TBPL1 P62380 TATA box-binding protein-like 1 chr6 GO:0043565 Not Cancer Driver No 27 0.145 6 0 0.0 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0043565 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0043565 Not Cancer Driver No 74 0.104 401 36 0.09 1
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0043565 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0043565 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0043565 Not Cancer Driver No 155 0.299 351 113 0.322 5
TCF12_ENST00000267811 TCF12 Q99081 Transcription factor 12 chr15 GO:0043565 Census Yes 105 0.154 680 105 0.154 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0043565 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCF21 TCF21 O43680 Transcription factor 21 chr6 GO:0043565 Not Cancer Driver No 55 0.307 120 40 0.333 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0043565 Census Yes 52 0.08 649 52 0.08 0
TCF4_ENST00000564999 TCF4 P15884 Transcription factor 4 chr18 GO:0043565 Compendium Yes 141 0.211 662 136 0.205 13
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0043565 Census, Compendium Yes 122 0.197 516 93 0.18 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0043565 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0043565 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0043565 Not Cancer Driver No 28 0.07 310 16 0.052 0
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0043565 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TET3 TET3 O43151 Methylcytosine dioxygenase TET3 chr2 GO:0043565 Not Cancer Driver No 208 0.116 1272 152 0.119 6
TFAM TFAM Q00059 Transcription factor A, mitochondrial chr10 GO:0043565 Not Cancer Driver No 25 0.102 110 15 0.136 1
TFAP2A TFAP2A P05549 Transcription factor AP-2-alpha chr6 GO:0043565 Not Cancer Driver No 77 0.176 275 44 0.16 4
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0043565 Not Cancer Driver No 114 0.248 306 75 0.245 6
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0043565 Compendium Yes 61 0.18 285 52 0.182 0
THAP1 THAP1 Q9NVV9 THAP domain-containing protein 1 chr8 GO:0043565 Not Cancer Driver No 19 0.089 76 8 0.105 45
THAP9 THAP9 Q9H5L6 DNA transposase THAP9 chr4 GO:0043565 Not Cancer Driver No 82 0.091 46 6 0.13 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0043565 Not Cancer Driver No 141 0.137 35 3 0.086 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 GO:0043565 Not Cancer Driver No 24 0.085 220 15 0.068 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0043565 Census, Compendium Yes 120 0.114 537 61 0.114 0
TSN TSN Q15631 Translin chr2 GO:0043565 Not Cancer Driver No 30 0.132 0 0 0.0 0
TSNAX TSNAX Q99598 Translin-associated protein X chr1 GO:0043565 Not Cancer Driver No 23 0.079 68 3 0.044 0
TSPYL2 TSPYL2 Q9H2G4 Testis-specific Y-encoded-like protein 2 chrX GO:0043565 Not Cancer Driver No 80 0.115 509 55 0.108 0
TSTD1 TSTD1 Q8NFU3 Thiosulfate:glutathione sulfurtransferase chr1 GO:0043565 Not Cancer Driver No 4 0.035 4 0 0.0 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0043565 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0043565 Not Cancer Driver No 100 0.131 567 77 0.136 1
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0043565 Not Cancer Driver No 97 0.122 353 49 0.139 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0043565 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0043565 Not Cancer Driver No 30 0.087 326 29 0.089 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0043565 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0043565 Not Cancer Driver No 34 0.117 210 22 0.105 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0043565 Not Cancer Driver No 64 0.15 102 16 0.157 14
VENTX VENTX O95231 Homeobox protein VENTX chr10 GO:0043565 Not Cancer Driver No 45 0.174 198 31 0.157 0
VRTN VRTN Q9H8Y1 Vertnin chr14 GO:0043565 Not Cancer Driver No 153 0.218 132 27 0.205 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 GO:0043565 Not Cancer Driver No 30 0.088 41 2 0.049 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0043565 Census, Compendium Yes 164 0.115 373 41 0.11 2
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0043565 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0043565 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRN2 XRN2 Q9H0D6 5'-3' exoribonuclease 2 chr20 GO:0043565 Not Cancer Driver No 129 0.136 427 63 0.148 0
YY2 YY2 O15391 Transcription factor YY2 chrX GO:0043565 Not Cancer Driver No 61 0.164 268 36 0.134 0
ZBED1 ZBED1 O96006 E3 SUMO-protein ligase ZBED1 chrX GO:0043565 Not Cancer Driver No 137 0.197 97 12 0.124 0
ZBTB14_ENST00000615385 ZBTB14 O43829 Zinc finger and BTB domain-containing protein 14 chr18 GO:0043565 Not Cancer Driver No 72 0.16 207 28 0.135 0
ZBTB18_ENST00000622512 ZBTB18 Q99592 Zinc finger and BTB domain-containing protein 18 chr1 GO:0043565 Not Cancer Driver No 78 0.149 236 25 0.106 0
ZBTB21 ZBTB21 Q9ULJ3 Zinc finger and BTB domain-containing protein 21 chr21 GO:0043565 Not Cancer Driver No 136 0.128 645 75 0.116 0
ZBTB33 ZBTB33 Q86T24 Transcriptional regulator Kaiso chrX GO:0043565 Not Cancer Driver No 110 0.164 352 58 0.165 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 GO:0043565 Not Cancer Driver No 137 0.115 648 73 0.113 0
ZBTB48 ZBTB48 P10074 Telomere zinc finger-associated protein chr1 GO:0043565 Not Cancer Driver No 53 0.077 237 16 0.068 0
ZBTB49 ZBTB49 Q6ZSB9 Zinc finger and BTB domain-containing protein 49 chr4 GO:0043565 Not Cancer Driver No 90 0.118 397 56 0.141 0
ZBTB4_ENST00000380599 ZBTB4 Q9P1Z0 Zinc finger and BTB domain-containing protein 4 chr17 GO:0043565 Not Cancer Driver No 140 0.138 788 109 0.138 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0043565 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCWPW1 ZCWPW1 Q9H0M4 Zinc finger CW-type PWWP domain protein 1 chr7 GO:0043565 Not Cancer Driver No 90 0.139 456 61 0.134 0
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0043565 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0043565 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFY_ENST00000155093 ZFY P08048 Zinc finger Y-chromosomal protein chrY GO:0043565 Not Cancer Driver No 29 0.036 357 8 0.022 0
ZGLP1 ZGLP1 P0C6A0 GATA-type zinc finger protein 1 chr19 GO:0043565 Not Cancer Driver No 24 0.089 191 17 0.089 0
ZGPAT ZGPAT Q8N5A5 Zinc finger CCCH-type with G patch domain-containing protein chr20 GO:0043565 Not Cancer Driver No 75 0.141 346 49 0.142 0
ZIC3 ZIC3 O60481 Zinc finger protein ZIC 3 chrX GO:0043565 Not Cancer Driver No 100 0.214 327 66 0.202 10
ZKSCAN3_ENST00000252211 ZKSCAN3 Q9BRR0 Zinc finger protein with KRAB and SCAN domains 3 chr6 GO:0043565 Not Cancer Driver No 70 0.13 267 30 0.112 0
ZNF140 ZNF140 P52738 Zinc finger protein 140 chr12 GO:0043565 Not Cancer Driver No 31 0.068 10 0 0.0 0
ZNF148_ENST00000485866 ZNF148 Q9UQR1 Zinc finger protein 148 chr3 GO:0043565 Compendium Yes 125 0.157 600 88 0.147 0
ZNF174_ENST00000571936 ZNF174 Q15697 Zinc finger protein 174 chr16 GO:0043565 Not Cancer Driver No 51 0.125 274 38 0.139 0
ZNF224 ZNF224 Q9NZL3 Zinc finger protein 224 chr19 GO:0043565 Not Cancer Driver No 98 0.139 138 14 0.101 0
ZNF24 ZNF24 P17028 Zinc finger protein 24 chr18 GO:0043565 Not Cancer Driver No 47 0.128 187 29 0.155 0
ZNF263 ZNF263 O14978 Zinc finger protein 263 chr16 GO:0043565 Not Cancer Driver No 90 0.132 403 58 0.144 0
ZNF274_ENST00000617501 ZNF274 Q96GC6 Neurotrophin receptor-interacting factor homolog chr19 GO:0043565 Not Cancer Driver No 88 0.135 396 56 0.141 0
ZNF281_ENST00000367353 ZNF281 Q9Y2X9 Zinc finger protein 281 chr1 GO:0043565 Not Cancer Driver No 92 0.103 709 67 0.094 0
ZNF300_ENST00000274599 ZNF300 Q96RE9 Zinc finger protein 300 chr5 GO:0043565 Not Cancer Driver No 124 0.205 76 24 0.316 0
ZNF35 ZNF35 P13682 Zinc finger protein 35 chr3 GO:0043565 Not Cancer Driver No 66 0.125 192 17 0.089 0
ZNF350 ZNF350 Q9GZX5 Zinc finger protein 350 chr19 GO:0043565 Not Cancer Driver No 86 0.162 95 18 0.189 0
ZNF423 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 GO:0043565 Not Cancer Driver No 340 0.265 416 108 0.26 2
ZNF536 ZNF536 O15090 Zinc finger protein 536 chr19 GO:0043565 Not Cancer Driver No 596 0.458 991 445 0.449 0
ZNF576_ENST00000525771 ZNF576 Q9H609 Zinc finger protein 576 chr19 GO:0043565 Not Cancer Driver No 32 0.188 86 15 0.174 0
ZNF672 ZNF672 Q499Z4 Zinc finger protein 672 chr1 GO:0043565 Not Cancer Driver No 52 0.115 131 16 0.122 0
ZNF711_ENST00000373165 ZNF711 Q9Y462 Zinc finger protein 711 chrX GO:0043565 Not Cancer Driver No 192 0.252 357 75 0.21 1
ZNF76 ZNF76 P36508 Zinc finger protein 76 chr6 GO:0043565 Not Cancer Driver No 66 0.116 330 39 0.118 0
ZNF787 ZNF787 Q6DD87 Zinc finger protein 787 chr19 GO:0043565 Not Cancer Driver No 33 0.086 232 18 0.078 0
ZSCAN10_ENST00000252463 ZSCAN10 Q96SZ4 Zinc finger and SCAN domain-containing protein 10 chr16 GO:0043565 Not Cancer Driver No 107 0.148 427 61 0.143 0
ZW10 ZW10 O43264 Centromere/kinetochore protein zw10 homolog chr11 GO:0043565 Not Cancer Driver No 90 0.116 63 11 0.175 0