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Total number of protein in "GO:0043410" GO term:  214

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0043410 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0043410 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA1B ADRA1B P35368 Alpha-1B adrenergic receptor chr5 GO:0043410 Not Cancer Driver No 53 0.102 132 1 0.008 0
ADRA1D ADRA1D P25100 Alpha-1D adrenergic receptor chr20 GO:0043410 Not Cancer Driver No 62 0.108 189 19 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0043410 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0043410 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0043410 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0043410 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADRB3 ADRB3 P13945 Beta-3 adrenergic receptor chr8 GO:0043410 Not Cancer Driver No 40 0.098 44 6 0.136 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0043410 Not Cancer Driver No 31 0.077 297 21 0.071 0
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0043410 Census, Compendium Yes 303 0.187 575 114 0.198 16
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0043410 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0043410 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALOX12B ALOX12B O75342 Arachidonate 12-lipoxygenase, 12R-type chr17 GO:0043410 Not Cancer Driver No 101 0.144 16 3 0.188 18
AR AR P10275 Androgen receptor chrX GO:0043410 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0043410 Not Cancer Driver No 170 0.106 1141 127 0.111 0
AVPI1 AVPI1 Q5T686 Arginine vasopressin-induced protein 1 chr10 GO:0043410 Not Cancer Driver No 21 0.143 115 14 0.122 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0043410 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0043410 Census, Compendium Yes 120 0.139 619 88 0.142 4
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0043410 Not Cancer Driver No 150 0.191 394 73 0.185 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0043410 Not Cancer Driver No 102 0.124 395 42 0.106 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0043410 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0043410 Not Cancer Driver No 86 0.211 142 26 0.183 5
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0043410 Not Cancer Driver No 61 0.217 96 17 0.177 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0043410 Not Cancer Driver No 18 0.155 0 0 0.0 0
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0043410 Not Cancer Driver No 20 0.123 5 2 0.4 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0043410 Not Cancer Driver No 10 0.102 7 0 0.0 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0043410 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0043410 Census Yes 31 0.105 185 20 0.108 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0043410 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0043410 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDK10 CDK10 Q15131 Cyclin-dependent kinase 10 chr16 GO:0043410 Not Cancer Driver No 42 0.117 30 4 0.133 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0043410 Not Cancer Driver No 71 0.141 18 4 0.222 0
CSPG4 CSPG4 Q6UVK1 Chondroitin sulfate proteoglycan 4 chr15 GO:0043410 Not Cancer Driver No 259 0.112 838 85 0.101 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0043410 Census, Compendium Yes 415 0.531 288 301 1.045 14
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0043410 Not Cancer Driver No 66 0.166 259 44 0.17 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043410 Not Cancer Driver No 131 0.11 681 68 0.1 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0043410 Not Cancer Driver No 53 0.075 125 12 0.096 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0043410 Not Cancer Driver No 58 0.218 47 8 0.17 0
DOK4_ENST00000340099 DOK4 Q8TEW6 Docking protein 4 chr16 GO:0043410 Not Cancer Driver No 42 0.129 45 3 0.067 0
DOK5 DOK5 Q9P104 Docking protein 5 chr20 GO:0043410 Not Cancer Driver No 87 0.284 15 7 0.467 0
DOK6 DOK6 Q6PKX4 Docking protein 6 chr18 GO:0043410 Not Cancer Driver No 98 0.296 48 11 0.229 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0043410 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0043410 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0043410 Not Cancer Driver No 97 0.135 437 58 0.133 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0043410 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0043410 Not Cancer Driver No 29 0.141 46 5 0.109 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0043410 Not Cancer Driver No 184 0.152 191 25 0.131 1
EIF2AK2_ENST00000395127 EIF2AK2 P19525 Interferon-induced, double-stranded RNA-activated protein kinase chr2 GO:0043410 Not Cancer Driver No 59 0.107 188 22 0.117 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0043410 Not Cancer Driver No 25 0.095 109 15 0.138 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0043410 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0043410 Not Cancer Driver No 197 0.196 121 17 0.14 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0043410 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0043410 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0043410 Not Cancer Driver No 192 0.207 213 45 0.211 0
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0043410 Not Cancer Driver No 73 0.172 19 2 0.105 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0043410 Not Cancer Driver No 193 0.263 217 44 0.203 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0043410 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0043410 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0043410 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0043410 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0043410 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0043410 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0043410 Census, Compendium Yes 238 0.29 228 44 0.193 72
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0043410 Census, Compendium Yes 173 0.215 241 26 0.108 37
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0043410 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0043410 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0043410 Census, Compendium Yes 253 0.186 259 41 0.158 13
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0043410 Not Cancer Driver No 69 0.136 415 58 0.14 0
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0043410 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0043410 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0043410 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0043410 Not Cancer Driver No 72 0.104 146 3 0.021 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0043410 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:0043410 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0043410 Not Cancer Driver No 13 0.082 20 2 0.1 0
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0043410 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0043410 Not Cancer Driver No 91 0.2 225 46 0.204 14
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:0043410 Not Cancer Driver No 176 0.447 5 2 0.4 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0043410 Not Cancer Driver No 20 0.171 52 11 0.212 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0043410 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 GO:0043410 Not Cancer Driver No 124 0.202 200 42 0.21 0
GPR37L1 GPR37L1 O60883 G-protein coupled receptor 37-like 1 chr1 GO:0043410 Not Cancer Driver No 62 0.129 81 8 0.099 0
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0043410 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM4 GRM4 Q14833 Metabotropic glutamate receptor 4 chr6 GO:0043410 Not Cancer Driver No 187 0.205 74 22 0.297 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0043410 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0043410 Not Cancer Driver No 81 0.163 14 3 0.214 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0043410 Not Cancer Driver No 47 0.217 124 29 0.234 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0043410 Compendium Yes 233 0.32 43 16 0.372 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0043410 Not Cancer Driver No 48 0.18 12 1 0.083 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0043410 Not Cancer Driver No 25 0.116 203 20 0.099 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0043410 Census, Compendium Yes 107 0.566 16 4 0.25 18
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0043410 Not Cancer Driver No 22 0.247 10 2 0.2 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0043410 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0043410 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0043410 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0043410 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP6 IGFBP6 P24592 Insulin-like growth factor-binding protein 6 chr12 GO:0043410 Not Cancer Driver No 22 0.092 166 18 0.108 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0043410 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0043410 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0043410 Not Cancer Driver No 35 0.165 58 7 0.121 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0043410 Not Cancer Driver No 112 0.169 553 98 0.177 1
INS INS P01308 Insulin chr11 GO:0043410 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0043410 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0043410 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0043410 Not Cancer Driver No 233 0.143 257 36 0.14 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0043410 Not Cancer Driver No 156 0.132 107 13 0.121 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0043410 Census, Compendium Yes 136 0.12 59 5 0.085 5
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0043410 Not Cancer Driver No 291 0.214 1337 290 0.217 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0043410 Census, Compendium Yes 357 0.263 275 55 0.2 2
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0043410 Not Cancer Driver No 17 0.123 116 14 0.121 1
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0043410 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:0043410 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:0043410 Not Cancer Driver No 139 0.133 6 1 0.167 0
KSR1_ENST00000644974 KSR1 Q8IVT5 Kinase suppressor of Ras 1 chr17 GO:0043410 Not Cancer Driver No 114 0.124 404 58 0.144 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0043410 Not Cancer Driver No 13 0.081 96 7 0.073 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0043410 Not Cancer Driver No 12 0.096 0 0 0.0 0
LAMTOR3 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 GO:0043410 Not Cancer Driver No 12 0.097 0 0 0.0 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0043410 Not Cancer Driver No 46 0.176 16 6 0.375 0
LEP LEP P41159 Leptin chr7 GO:0043410 Not Cancer Driver No 29 0.174 0 0 0.0 2
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0043410 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0043410 Not Cancer Driver No 79 0.264 98 19 0.194 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0043410 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0043410 Not Cancer Driver No 65 0.184 9 0 0.0 0
MADD MADD Q8WXG6 MAP kinase-activating death domain protein chr11 GO:0043410 Not Cancer Driver No 207 0.126 723 81 0.112 4
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0043410 Census Yes 58 0.145 105 14 0.133 4
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0043410 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0043410 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0043410 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0043410 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0043410 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0043410 Census Yes 157 0.163 593 91 0.153 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0043410 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0043410 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0043410 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0043410 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0043410 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0043410 Not Cancer Driver No 78 0.095 243 23 0.095 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0043410 Not Cancer Driver No 95 0.09 98 9 0.092 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0043410 Not Cancer Driver No 113 0.085 740 56 0.076 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0043410 Not Cancer Driver No 73 0.156 115 19 0.165 0
MOS MOS P00540 Proto-oncogene serine/threonine-protein kinase mos chr8 GO:0043410 Not Cancer Driver No 94 0.272 16 4 0.25 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0043410 Not Cancer Driver No 23 0.133 26 4 0.154 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0043410 Not Cancer Driver No 37 0.095 181 12 0.066 1
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0043410 Not Cancer Driver No 117 0.133 22 1 0.045 4
NENF NENF Q9UMX5 Neudesin chr1 GO:0043410 Not Cancer Driver No 15 0.087 98 7 0.071 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0043410 Not Cancer Driver No 155 0.189 117 18 0.154 1
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0043410 Not Cancer Driver No 117 0.308 18 5 0.278 0
OSM OSM P13725 Oncostatin-M chr22 GO:0043410 Not Cancer Driver No 43 0.171 114 24 0.211 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0043410 Not Cancer Driver No 57 0.105 299 30 0.1 2
PDE6G PDE6G P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr17 GO:0043410 Not Cancer Driver No 15 0.172 58 11 0.19 0
PDE6H PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 GO:0043410 Not Cancer Driver No 15 0.181 59 14 0.237 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0043410 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0043410 Census Yes 37 0.154 99 22 0.222 2
PELI2 PELI2 Q9HAT8 E3 ubiquitin-protein ligase pellino homolog 2 chr14 GO:0043410 Not Cancer Driver No 80 0.19 162 38 0.235 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0043410 Not Cancer Driver No 31 0.104 26 4 0.154 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0043410 Not Cancer Driver No 80 0.113 598 66 0.11 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0043410 Not Cancer Driver No 367 0.159 780 107 0.137 1
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0043410 Not Cancer Driver No 248 0.196 142 30 0.211 1
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0043410 Not Cancer Driver No 11 0.067 24 3 0.125 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0043410 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0043410 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0043410 Not Cancer Driver No 50 0.135 18 1 0.056 0
PROK1 PROK1 P58294 Prokineticin-1 chr1 GO:0043410 Not Cancer Driver No 21 0.2 0 0 0.0 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0043410 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0043410 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0043410 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0043410 Not Cancer Driver No 184 0.138 401 61 0.152 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0043410 Census, Compendium Yes 89 0.137 169 38 0.225 22
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:0043410 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:0043410 Not Cancer Driver No 39 0.129 259 37 0.143 0
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0043410 Census, Compendium Yes 208 0.187 105 12 0.114 139
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0043410 Not Cancer Driver No 74 0.341 29 11 0.379 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0043410 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0043410 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0043410 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0043410 Not Cancer Driver No 22 0.091 48 4 0.083 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0043410 Not Cancer Driver No 55 0.091 85 4 0.047 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0043410 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0043410 Not Cancer Driver No 84 0.144 397 58 0.146 0
SHC2 SHC2 P98077 SHC-transforming protein 2 chr19 GO:0043410 Not Cancer Driver No 66 0.113 362 44 0.122 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043410 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORBS3 SORBS3 O60504 Vinexin chr8 GO:0043410 Not Cancer Driver No 62 0.092 577 56 0.097 0
SOX2 SOX2 P48431 Transcription factor SOX-2 chr3 GO:0043410 Census Yes 39 0.123 312 39 0.125 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0043410 Not Cancer Driver No 128 0.097 841 81 0.096 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0043410 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0043410 Not Cancer Driver No 46 0.17 187 34 0.182 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0043410 Not Cancer Driver No 64 0.117 182 19 0.104 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0043410 Census Yes 96 0.151 131 27 0.206 5
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0043410 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0043410 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0043410 Not Cancer Driver No 35 0.088 197 12 0.061 4
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0043410 Not Cancer Driver No 39 0.207 25 2 0.08 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0043410 Not Cancer Driver No 219 0.195 126 22 0.175 10
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0043410 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0043410 Not Cancer Driver No 86 0.171 23 3 0.13 15
THPO THPO P40225 Thrombopoietin chr3 GO:0043410 Not Cancer Driver No 63 0.178 163 25 0.153 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0043410 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0043410 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0043410 Not Cancer Driver No 26 0.099 9 1 0.111 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043410 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0043410 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0043410 Not Cancer Driver No 52 0.164 56 1 0.018 1
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0043410 Not Cancer Driver No 82 0.129 443 55 0.124 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0043410 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0043410 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0043410 Census Yes 76 0.113 120 14 0.117 4
TRIM5 TRIM5 Q9C035 Tripartite motif-containing protein 5 chr11 GO:0043410 Not Cancer Driver No 71 0.144 77 11 0.143 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0043410 Not Cancer Driver No 27 0.116 41 7 0.171 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043410 Not Cancer Driver No 66 0.174 0 0 0.0 2
WWC1_ENST00000265293 WWC1 Q8IX03 Protein KIBRA chr5 GO:0043410 Not Cancer Driver No 147 0.132 550 81 0.147 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0043410 Not Cancer Driver No 279 0.209 134 24 0.179 1
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0043410 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZNF622 ZNF622 Q969S3 Zinc finger protein 622 chr5 GO:0043410 Not Cancer Driver No 66 0.138 220 33 0.15 0