Total number of protein in "GO:0043124" GO term: 45
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0043124 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0043124 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
ASH1L_ENST00000368346 | ASH1L | Q9NR48 | Histone-lysine N-methyltransferase ASH1L | chr1 | GO:0043124 | Not Cancer Driver | No | 415 | 0.14 | 1858 | 256 | 0.138 | 1 |
CACTIN | CACTIN | Q8WUQ7 | Cactin | chr19 | GO:0043124 | Not Cancer Driver | No | 94 | 0.124 | 503 | 54 | 0.107 | 0 |
CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0043124 | Not Cancer Driver | No | 53 | 0.099 | 126 | 7 | 0.056 | 1 |
CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0043124 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
CCDC22 | CCDC22 | O60826 | Coiled-coil domain-containing protein 22 | chrX | GO:0043124 | Not Cancer Driver | No | 62 | 0.099 | 243 | 18 | 0.074 | 2 |
DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0043124 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0043124 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
GSTP1_ENST00000642444 | GSTP1 | P09211 | Glutathione S-transferase P | chr11 | GO:0043124 | Not Cancer Driver | No | 32 | 0.152 | 0 | 0 | 0.0 | 0 |
HDAC1 | HDAC1 | Q13547 | Histone deacetylase 1 | chr1 | GO:0043124 | Not Cancer Driver | No | 47 | 0.098 | 135 | 10 | 0.074 | 0 |
LILRB4 | LILRB4 | Q8NHJ6 | Leukocyte immunoglobulin-like receptor subfamily B member 4 | chr19 | GO:0043124 | Not Cancer Driver | No | 162 | 0.362 | 277 | 115 | 0.415 | 0 |
MAPKBP1 | MAPKBP1 | O60336 | Mitogen-activated protein kinase-binding protein 1 | chr15 | GO:0043124 | Not Cancer Driver | No | 166 | 0.11 | 786 | 67 | 0.085 | 0 |
NLRC3 | NLRC3 | Q7RTR2 | NLR family CARD domain-containing protein 3 | chr16 | GO:0043124 | Not Cancer Driver | No | 176 | 0.165 | 147 | 33 | 0.224 | 0 |
NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0043124 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0043124 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
NLRX1_ENST00000409265 | NLRX1 | Q86UT6 | NLR family member X1 | chr11 | GO:0043124 | Not Cancer Driver | No | 158 | 0.162 | 94 | 13 | 0.138 | 0 |
NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0043124 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
NR1H4 | NR1H4 | Q96RI1 | Bile acid receptor | chr12 | GO:0043124 | Not Cancer Driver | No | 111 | 0.228 | 78 | 18 | 0.231 | 0 |
OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | GO:0043124 | Not Cancer Driver | No | 58 | 0.101 | 470 | 51 | 0.109 | 6 |
OTUD7A | OTUD7A | Q8TE49 | OTU domain-containing protein 7A | chr15 | GO:0043124 | Not Cancer Driver | No | 121 | 0.131 | 591 | 65 | 0.11 | 0 |
OTUD7B | OTUD7B | Q6GQQ9 | OTU domain-containing protein 7B | chr1 | GO:0043124 | Not Cancer Driver | No | 124 | 0.147 | 537 | 87 | 0.162 | 0 |
PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0043124 | Census | Yes | 160 | 0.124 | 948 | 116 | 0.122 | 0 |
PPM1A_ENST00000395076 | PPM1A | P35813 | Protein phosphatase 1A | chr14 | GO:0043124 | Not Cancer Driver | No | 60 | 0.157 | 134 | 24 | 0.179 | 0 |
PPM1B | PPM1B | O75688 | Protein phosphatase 1B | chr2 | GO:0043124 | Not Cancer Driver | No | 65 | 0.136 | 243 | 31 | 0.128 | 0 |
PPM1N | PPM1N | Q8N819 | Probable protein phosphatase 1N | chr19 | GO:0043124 | Not Cancer Driver | No | 31 | 0.072 | 152 | 7 | 0.046 | 0 |
PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0043124 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0043124 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
RHOH_ENST00000617441 | RHOH | Q15669 | Rho-related GTP-binding protein RhoH | chr4 | GO:0043124 | Census | Yes | 41 | 0.215 | 12 | 3 | 0.25 | 0 |
RIOK3 | RIOK3 | O14730 | Serine/threonine-protein kinase RIO3 | chr18 | GO:0043124 | Not Cancer Driver | No | 58 | 0.112 | 225 | 21 | 0.093 | 0 |
RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0043124 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0043124 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |
SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0043124 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0043124 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
TANK | TANK | Q92844 | TRAF family member-associated NF-kappa-B activator | chr2 | GO:0043124 | Not Cancer Driver | No | 42 | 0.099 | 302 | 26 | 0.086 | 0 |
TLE1 | TLE1 | Q04724 | Transducin-like enhancer protein 1 | chr9 | GO:0043124 | Not Cancer Driver | No | 111 | 0.144 | 381 | 53 | 0.139 | 0 |
TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0043124 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
TNIP1_ENST00000522226 | TNIP1 | Q15025 | TNFAIP3-interacting protein 1 | chr5 | GO:0043124 | Not Cancer Driver | No | 85 | 0.134 | 625 | 83 | 0.133 | 0 |
TNIP3_ENST00000057513 | TNIP3 | Q96KP6 | TNFAIP3-interacting protein 3 | chr4 | GO:0043124 | Not Cancer Driver | No | 97 | 0.298 | 249 | 72 | 0.289 | 0 |
TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0043124 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
TRIM39 | TRIM39 | Q9HCM9 | E3 ubiquitin-protein ligase TRIM39 | chr6 | GO:0043124 | Not Cancer Driver | No | 74 | 0.143 | 62 | 8 | 0.129 | 0 |
TRIM59 | TRIM59 | Q8IWR1 | Tripartite motif-containing protein 59 | chr3 | GO:0043124 | Not Cancer Driver | No | 47 | 0.117 | 33 | 6 | 0.182 | 0 |
USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0043124 | Not Cancer Driver | No | 92 | 0.115 | 425 | 49 | 0.115 | 0 |
ZC3H12A | ZC3H12A | Q5D1E8 | Endoribonuclease ZC3H12A | chr1 | GO:0043124 | Not Cancer Driver | No | 90 | 0.15 | 396 | 44 | 0.111 | 0 |
ZMYND11 | ZMYND11 | Q15326 | Zinc finger MYND domain-containing protein 11 | chr10 | GO:0043124 | Not Cancer Driver | No | 71 | 0.118 | 184 | 26 | 0.141 | 0 |