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Total number of protein in "GO:0043085" GO term:  629

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0043085 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0043085 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0043085 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0043085 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABR ABR Q12979 Active breakpoint cluster region-related protein chr17 GO:0043085 Not Cancer Driver No 122 0.142 184 36 0.196 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0043085 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0043085 Not Cancer Driver No 201 0.154 86 8 0.093 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0043085 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0043085 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0043085 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0043085 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0043085 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADPRH ADPRH P54922 ADP-ribosylhydrolase ARH1 chr3 GO:0043085 Not Cancer Driver No 54 0.151 30 3 0.1 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0043085 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0043085 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0043085 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0043085 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0043085 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0043085 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0043085 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0043085 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGT AGT P01019 Angiotensinogen chr1 GO:0043085 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0043085 Not Cancer Driver No 95 0.265 0 0 0.0 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0043085 Not Cancer Driver No 98 0.27 0 0 0.0 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 GO:0043085 Not Cancer Driver No 46 0.144 61 8 0.131 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0043085 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0043085 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0043085 Census Yes 77 0.16 84 9 0.107 2
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0043085 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0043085 Not Cancer Driver No 7 0.046 31 0 0.0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0043085 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANG ANG P03950 Angiogenin chr14 GO:0043085 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0043085 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0043085 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0043085 Not Cancer Driver No 105 0.186 183 44 0.24 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0043085 Not Cancer Driver No 127 0.102 17 1 0.059 0
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0043085 Not Cancer Driver No 117 0.051 1725 78 0.045 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0043085 Not Cancer Driver No 32 0.121 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0043085 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0043085 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0043085 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0043085 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0043085 Not Cancer Driver No 25 0.079 124 6 0.048 12
APOH APOH P02749 Beta-2-glycoprotein 1 chr17 GO:0043085 Not Cancer Driver No 67 0.194 0 0 0.0 0
APOPT1 COA8 Q96IL0 Cytochrome c oxidase assembly factor 8 chr14 GO:0043085 Not Cancer Driver No 23 0.112 48 4 0.083 0
AREG AREG P15514 Amphiregulin chr4 GO:0043085 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0043085 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARHGAP22_ENST00000249601 ARHGAP22 Q7Z5H3 Rho GTPase-activating protein 22 chr10 GO:0043085 Not Cancer Driver No 138 0.198 449 90 0.2 0
ARHGAP24 ARHGAP24 Q8N264 Rho GTPase-activating protein 24 chr4 GO:0043085 Not Cancer Driver No 103 0.138 482 67 0.139 0
ARHGAP25 ARHGAP25 P42331 Rho GTPase-activating protein 25 chr2 GO:0043085 Not Cancer Driver No 120 0.186 339 62 0.183 0
ARHGAP29 ARHGAP29 Q52LW3 Rho GTPase-activating protein 29 chr1 GO:0043085 Not Cancer Driver No 182 0.144 579 94 0.162 0
ARHGAP42 ARHGAP42 A6NI28 Rho GTPase-activating protein 42 chr11 GO:0043085 Not Cancer Driver No 63 0.072 311 17 0.055 0
ARHGAP45_ENST00000313093 ARHGAP45 Q92619 Rho GTPase-activating protein 45 chr19 GO:0043085 Not Cancer Driver No 110 0.097 679 68 0.1 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0043085 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0043085 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0043085 Not Cancer Driver No 68 0.096 297 13 0.044 0
ARHGEF19 ARHGEF19 Q8IW93 Rho guanine nucleotide exchange factor 19 chr1 GO:0043085 Not Cancer Driver No 82 0.102 365 36 0.099 0
ARHGEF26 ARHGEF26 Q96DR7 Rho guanine nucleotide exchange factor 26 chr3 GO:0043085 Not Cancer Driver No 164 0.188 475 86 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0043085 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL1 ARL1 P40616 ADP-ribosylation factor-like protein 1 chr12 GO:0043085 Not Cancer Driver No 17 0.094 4 0 0.0 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 GO:0043085 Not Cancer Driver No 52 0.126 95 12 0.126 0
ARRDC4 ARRDC4 Q8NCT1 Arrestin domain-containing protein 4 chr15 GO:0043085 Not Cancer Driver No 52 0.124 53 12 0.226 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0043085 Not Cancer Driver No 109 0.144 373 53 0.142 1
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0043085 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0043085 Not Cancer Driver No 228 0.152 171 46 0.269 52
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0043085 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0043085 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0043085 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZIN2_ENST00000294517 AZIN2 Q96A70 Antizyme inhibitor 2 chr1 GO:0043085 Not Cancer Driver No 51 0.111 14 0 0.0 0
B3GAT3 B3GAT3 O94766 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 chr11 GO:0043085 Not Cancer Driver No 42 0.125 139 17 0.122 2
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0043085 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0043085 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0043085 Census Yes 30 0.156 39 2 0.051 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0043085 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0043085 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0043085 Census, Compendium Yes 146 0.115 603 69 0.114 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0043085 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0043085 Not Cancer Driver No 73 0.184 139 26 0.187 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0043085 Not Cancer Driver No 7 0.033 0 0 0.0 0
BTC BTC P35070 Probetacellulin chr4 GO:0043085 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0043085 Not Cancer Driver No 80 0.132 45 4 0.089 0
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0043085 Not Cancer Driver No 38 0.11 29 2 0.069 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0043085 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0043085 Census, Compendium Yes 342 0.158 736 126 0.171 2
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0043085 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0043085 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0043085 Not Cancer Driver No 17 0.114 115 10 0.087 3
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0043085 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0043085 Not Cancer Driver No 99 0.099 296 36 0.122 11
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0043085 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0043085 Census Yes 49 0.118 71 7 0.099 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0043085 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0043085 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCDC125_ENST00000396499 CCDC125 Q86Z20 Coiled-coil domain-containing protein 125 chr5 GO:0043085 Not Cancer Driver No 58 0.114 261 23 0.088 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0043085 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0043085 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0043085 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0043085 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0043085 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0043085 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0043085 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0043085 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0043085 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0043085 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0043085 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0043085 Not Cancer Driver No 31 0.086 100 8 0.08 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0043085 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCS CCS O14618 Copper chaperone for superoxide dismutase chr11 GO:0043085 Not Cancer Driver No 28 0.102 105 10 0.095 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0043085 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0043085 Not Cancer Driver No 51 0.095 92 2 0.022 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0043085 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD200_ENST00000315711 CD200 P41217 OX-2 membrane glycoprotein chr3 GO:0043085 Not Cancer Driver No 37 0.133 14 0 0.0 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0043085 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0043085 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0043085 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0043085 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0043085 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0043085 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0043085 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0043085 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0043085 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0043085 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0043085 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0043085 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0043085 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0043085 Census, Compendium Yes 19 0.096 198 19 0.096 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0043085 Not Cancer Driver No 207 0.152 105 10 0.095 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0043085 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0043085 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0043085 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0043085 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0043085 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0043085 Not Cancer Driver No 13 0.107 7 0 0.0 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0043085 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0043085 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0043085 Not Cancer Driver No 19 0.087 23 1 0.043 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0043085 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0043085 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0043085 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0043085 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0043085 Not Cancer Driver No 69 0.154 156 27 0.173 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0043085 Not Cancer Driver No 25 0.12 14 2 0.143 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0043085 Not Cancer Driver No 61 0.129 84 13 0.155 0
COX17_ENST00000497116 COX17 Q14061 Cytochrome c oxidase copper chaperone chr3 GO:0043085 Not Cancer Driver No 7 0.111 15 2 0.133 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0043085 Compendium Yes 383 0.188 151 42 0.278 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0043085 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0043085 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0043085 Census Yes 133 0.137 124 17 0.137 20
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0043085 Census, Compendium Yes 415 0.531 288 301 1.045 14
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0043085 Not Cancer Driver No 11 0.101 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0043085 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0043085 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0043085 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0043085 Not Cancer Driver No 71 0.14 79 13 0.165 18
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0043085 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAOA_ENST00000375936 DAOA P59103 D-amino acid oxidase activator chr13 GO:0043085 Not Cancer Driver No 45 0.294 53 20 0.377 0
DBI_ENST00000355857 DBI P07108 Acyl-CoA-binding protein chr2 GO:0043085 Not Cancer Driver No 13 0.149 27 6 0.222 0
DCP1A DCP1A Q9NPI6 mRNA-decapping enzyme 1A chr3 GO:0043085 Not Cancer Driver No 46 0.079 382 31 0.081 0
DCP1B DCP1B Q8IZD4 mRNA-decapping enzyme 1B chr12 GO:0043085 Not Cancer Driver No 82 0.133 406 63 0.155 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0043085 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0043085 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0043085 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0043085 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0043085 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0043085 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0043085 Not Cancer Driver No 154 0.159 280 55 0.196 1
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0043085 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0043085 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHFR DHFR P00374 Dihydrofolate reductase chr5 GO:0043085 Not Cancer Driver No 16 0.086 12 2 0.167 2
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0043085 Compendium Yes 182 0.143 331 42 0.127 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0043085 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0043085 Not Cancer Driver No 56 0.13 9 0 0.0 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0043085 Not Cancer Driver No 62 0.121 145 29 0.2 24
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0043085 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0043085 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0043085 Not Cancer Driver No 116 0.16 232 55 0.237 0
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0043085 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0043085 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0043085 Not Cancer Driver No 52 0.103 286 27 0.094 19
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0043085 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0043085 Not Cancer Driver No 28 0.071 41 4 0.098 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0043085 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0043085 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0043085 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0043085 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0043085 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0043085 Not Cancer Driver No 54 0.257 78 21 0.269 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0043085 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0043085 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDN2 EDN2 P20800 Endothelin-2 chr1 GO:0043085 Not Cancer Driver No 21 0.118 87 13 0.149 0
EDN3_ENST00000371028 EDN3 P14138 Endothelin-3 chr20 GO:0043085 Not Cancer Driver No 69 0.29 140 44 0.314 3
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 GO:0043085 Not Cancer Driver No 74 0.16 121 17 0.14 3
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0043085 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0043085 Not Cancer Driver No 24 0.101 31 11 0.355 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0043085 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0043085 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0043085 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0043085 Not Cancer Driver No 78 0.144 501 72 0.144 0
EPGN EPGN Q6UW88 Epigen chr4 GO:0043085 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0043085 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0043085 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0043085 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0043085 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0043085 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0043085 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0043085 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0043085 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0043085 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0043085 Not Cancer Driver No 192 0.207 213 45 0.211 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0043085 Not Cancer Driver No 70 0.088 381 27 0.071 0
EVI5_ENST00000370331 EVI5 O60447 Ecotropic viral integration site 5 protein homolog chr1 GO:0043085 Not Cancer Driver No 115 0.142 416 61 0.147 0
F2 F2 P00734 Prothrombin chr11 GO:0043085 Not Cancer Driver No 115 0.185 97 25 0.258 10
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0043085 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM173A ANTKMT Q9BQD7 Adenine nucleotide translocase lysine N-methyltransferase chr16 GO:0043085 Not Cancer Driver No 10 0.043 37 3 0.081 0
FAM173B ATPSCKMT Q6P4H8 ATP synthase subunit C lysine N-methyltransferase chr5 GO:0043085 Not Cancer Driver No 41 0.176 10 1 0.1 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0043085 Census, Compendium Yes 55 0.164 62 18 0.29 22
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0043085 Census, Compendium Yes 322 0.455 230 38 0.165 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0043085 Not Cancer Driver No 41 0.128 130 22 0.169 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0043085 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0043085 Not Cancer Driver No 193 0.263 217 44 0.203 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0043085 Not Cancer Driver No 12 0.065 61 2 0.033 0
FDX2 FDX2 Q6P4F2 Ferredoxin-2, mitochondrial chr19 GO:0043085 Not Cancer Driver No 26 0.14 102 14 0.137 1
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0043085 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0043085 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0043085 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0043085 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0043085 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0043085 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0043085 Census, Compendium Yes 113 0.141 162 28 0.173 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0043085 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0043085 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0043085 Census, Compendium Yes 200 0.201 64 27 0.422 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0043085 Not Cancer Driver No 43 0.113 92 12 0.13 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0043085 Not Cancer Driver No 25 0.059 279 18 0.065 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0043085 Not Cancer Driver No 96 0.274 26 5 0.192 0
FTMT FTMT Q8N4E7 Ferritin, mitochondrial chr5 GO:0043085 Not Cancer Driver No 96 0.397 93 33 0.355 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0043085 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0043085 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0043085 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0043085 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0043085 Not Cancer Driver No 72 0.104 146 3 0.021 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0043085 Not Cancer Driver No 74 0.149 184 30 0.163 0
GARNL3 GARNL3 Q5VVW2 GTPase-activating Rap/Ran-GAP domain-like protein 3 chr9 GO:0043085 Not Cancer Driver No 115 0.114 285 34 0.119 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0043085 Not Cancer Driver No 82 0.121 42 6 0.143 0
GBA3 GBA3 Q9H227 Cytosolic beta-glucosidase chr4 GO:0043085 Not Cancer Driver No 118 0.252 18 6 0.333 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0043085 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0043085 Not Cancer Driver No 32 0.117 31 3 0.097 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0043085 Not Cancer Driver No 47 0.223 83 18 0.217 2
GH1 GH1 P01241 Somatotropin chr17 GO:0043085 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0043085 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0043085 Not Cancer Driver No 173 0.271 229 66 0.288 19
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0043085 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0043085 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0043085 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0043085 Not Cancer Driver No 32 0.143 77 14 0.182 0
GMIP GMIP Q9P107 GEM-interacting protein chr19 GO:0043085 Not Cancer Driver No 124 0.128 597 67 0.112 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0043085 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNA13 GNA13 Q14344 Guanine nucleotide-binding protein subunit alpha-13 chr17 GO:0043085 Compendium Yes 52 0.138 32 4 0.125 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0043085 Compendium Yes 50 0.141 24 0 0.0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0043085 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0043085 Not Cancer Driver No 43 0.123 39 6 0.154 3
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0043085 Not Cancer Driver No 26 0.141 82 15 0.183 10
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0043085 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0043085 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0043085 Not Cancer Driver No 82 0.203 75 19 0.253 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0043085 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0043085 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0043085 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0043085 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0043085 Not Cancer Driver No 76 0.128 29 6 0.207 1
GRTP1_ENST00000375431 GRTP1 Q5TC63 Growth hormone-regulated TBC protein 1 chr13 GO:0043085 Not Cancer Driver No 58 0.173 39 3 0.077 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0043085 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSN GSN P06396 Gelsolin chr9 GO:0043085 Not Cancer Driver No 76 0.097 316 28 0.089 2
GTF2H2_ENST00000330280 GTF2H2 Q13888 General transcription factor IIH subunit 2 chr5 GO:0043085 Not Cancer Driver No 7 0.018 43 1 0.023 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0043085 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0043085 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0043085 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0043085 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0043085 Not Cancer Driver No 17 0.152 0 0 0.0 0
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0043085 Not Cancer Driver No 16 0.077 63 3 0.048 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0043085 Census Yes 118 0.143 435 51 0.117 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0043085 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0043085 Not Cancer Driver No 38 0.182 207 38 0.184 0
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0043085 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0043085 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0043085 Not Cancer Driver No 77 0.093 504 45 0.089 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0043085 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0043085 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0043085 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0043085 Not Cancer Driver No 24 0.037 200 13 0.065 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0043085 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0043085 Compendium Yes 44 0.096 127 9 0.071 2
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0043085 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0043085 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0043085 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0043085 Not Cancer Driver No 39 0.217 44 12 0.273 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0043085 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0043085 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0043085 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0043085 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0043085 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0043085 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0043085 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0043085 Not Cancer Driver No 55 0.118 165 23 0.139 1
INS INS P01308 Insulin chr11 GO:0043085 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0043085 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0043085 Compendium Yes 71 0.1 337 39 0.116 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0043085 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0043085 Not Cancer Driver No 14 0.084 24 3 0.125 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0043085 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0043085 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0043085 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0043085 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0043085 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0043085 Census, Compendium Yes 136 0.12 59 5 0.085 5
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0043085 Census, Compendium Yes 226 0.232 83 33 0.398 21
LEP LEP P41159 Leptin chr7 GO:0043085 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0043085 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0043085 Not Cancer Driver No 57 0.132 112 19 0.17 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0043085 Not Cancer Driver No 79 0.264 98 19 0.194 0
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0043085 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0043085 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0043085 Census Yes 95 0.186 84 12 0.143 0
MAGEC2 MAGEC2 Q9UBF1 Melanoma-associated antigen C2 chrX GO:0043085 Not Cancer Driver No 170 0.456 129 69 0.535 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0043085 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0043085 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0043085 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0043085 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0043085 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0043085 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0043085 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0043085 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0043085 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0043085 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0043085 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0043085 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0043085 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0043085 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0043085 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0043085 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0043085 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0043085 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0043085 Not Cancer Driver No 128 0.169 750 126 0.168 18
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0043085 Not Cancer Driver No 47 0.145 5 2 0.4 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0043085 Not Cancer Driver No 90 0.102 389 44 0.113 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0043085 Not Cancer Driver No 52 0.171 304 52 0.171 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0043085 Not Cancer Driver No 92 0.195 408 81 0.199 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0043085 Not Cancer Driver No 23 0.126 83 6 0.072 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0043085 Not Cancer Driver No 23 0.074 64 2 0.031 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0043085 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0043085 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0043085 Census Yes 154 0.113 386 41 0.106 6
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0043085 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0043085 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0043085 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0043085 Not Cancer Driver No 62 0.083 582 49 0.084 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0043085 Census, Compendium Yes 80 0.182 299 46 0.154 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0043085 Census Yes 67 0.128 395 51 0.129 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0043085 Not Cancer Driver No 61 0.123 386 44 0.114 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0043085 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0043085 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0043085 Not Cancer Driver No 32 0.093 202 16 0.079 0
NDUFA4 NDUFA4 O00483 Cytochrome c oxidase subunit NDUFA4 chr7 GO:0043085 Not Cancer Driver No 14 0.173 4 0 0.0 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0043085 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0043085 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0043085 Not Cancer Driver No 35 0.116 23 0 0.0 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0043085 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0043085 Census, Compendium Yes 375 0.132 406 47 0.116 85
NGEF NGEF Q8N5V2 Ephexin-1 chr2 GO:0043085 Not Cancer Driver No 125 0.176 296 34 0.115 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0043085 Not Cancer Driver No 35 0.117 83 8 0.096 2
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0043085 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0043085 Not Cancer Driver No 106 0.119 203 28 0.138 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0043085 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0043085 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0043085 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0043085 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0043085 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0043085 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0043085 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0043085 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0043085 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPR3 NPR3 P17342 Atrial natriuretic peptide receptor 3 chr5 GO:0043085 Not Cancer Driver No 95 0.176 58 8 0.138 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0043085 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0043085 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0043085 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0043085 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0043085 Not Cancer Driver No 227 0.315 425 134 0.315 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0043085 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0043085 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0043085 Not Cancer Driver No 21 0.072 13 0 0.0 1
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0043085 Not Cancer Driver No 90 0.105 267 31 0.116 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0043085 Not Cancer Driver No 26 0.086 101 9 0.089 5
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0043085 Not Cancer Driver No 105 0.118 401 37 0.092 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0043085 Not Cancer Driver No 57 0.167 21 2 0.095 3
PABPN1 PABPN1 Q86U42 Polyadenylate-binding protein 2 chr14 GO:0043085 Not Cancer Driver No 27 0.088 241 18 0.075 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0043085 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0043085 Compendium Yes 89 0.17 242 49 0.202 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0043085 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0043085 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0043085 Not Cancer Driver No 71 0.111 197 22 0.112 2
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0043085 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0043085 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0043085 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0043085 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0043085 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDP1_ENST00000297598 PDP1 Q9P0J1 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial chr8 GO:0043085 Not Cancer Driver No 64 0.119 96 9 0.094 0
PDP2 PDP2 Q9P2J9 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial chr16 GO:0043085 Not Cancer Driver No 52 0.098 51 11 0.216 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0043085 Not Cancer Driver No 33 0.059 121 12 0.099 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0043085 Not Cancer Driver No 28 0.145 0 0 0.0 1
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0043085 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0043085 Not Cancer Driver No 68 0.135 97 18 0.186 0
PHACTR4_ENST00000373839 PHACTR4 Q8IZ21 Phosphatase and actin regulator 4 chr1 GO:0043085 Not Cancer Driver No 80 0.114 679 76 0.112 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0043085 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0043085 Not Cancer Driver No 37 0.136 4 1 0.25 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0043085 Not Cancer Driver No 83 0.11 419 45 0.107 2
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0043085 Census Yes 89 0.137 320 42 0.131 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0043085 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0043085 Not Cancer Driver No 193 0.142 315 45 0.143 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0043085 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0043085 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0043085 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0043085 Not Cancer Driver No 74 0.132 216 29 0.134 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0043085 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0043085 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0043085 Not Cancer Driver No 13 0.167 78 13 0.167 0
PLA2G1B PLA2G1B P04054 Phospholipase A2 chr12 GO:0043085 Not Cancer Driver No 17 0.115 0 0 0.0 0
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 GO:0043085 Not Cancer Driver No 78 0.098 150 14 0.093 2
PLEK PLEK P08567 Pleckstrin chr2 GO:0043085 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0043085 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0043085 Not Cancer Driver No 43 0.135 92 13 0.141 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0043085 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0043085 Not Cancer Driver No 124 0.267 32 11 0.344 1
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0043085 Not Cancer Driver No 64 0.132 46 4 0.087 3
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0043085 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0043085 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0043085 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0043085 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0043085 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0043085 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0043085 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0043085 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0043085 Not Cancer Driver No 14 0.039 198 11 0.056 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0043085 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0043085 Compendium Yes 79 0.117 43 9 0.209 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0043085 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0043085 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0043085 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0043085 Compendium Yes 118 0.134 246 34 0.138 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0043085 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRNP PRNP P04156 Major prion protein chr20 GO:0043085 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0043085 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0043085 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0043085 Not Cancer Driver No 42 0.094 235 24 0.102 0
PSAP PSAP P07602 Prosaposin chr10 GO:0043085 Not Cancer Driver No 59 0.113 28 2 0.071 8
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0043085 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSEN2 PSEN2 P49810 Presenilin-2 chr1 GO:0043085 Not Cancer Driver No 68 0.152 89 16 0.18 7
PSENEN_ENST00000222266 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 GO:0043085 Not Cancer Driver No 17 0.168 0 0 0.0 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0043085 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0043085 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0043085 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0043085 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0043085 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0043085 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0043085 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0043085 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0043085 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0043085 Not Cancer Driver No 16 0.082 39 4 0.103 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 GO:0043085 Not Cancer Driver No 114 0.107 407 40 0.098 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 GO:0043085 Not Cancer Driver No 116 0.142 235 33 0.14 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0043085 Not Cancer Driver No 34 0.107 13 0 0.0 0
RALGAPA1_ENST00000389698 RALGAPA1 Q6GYQ0 Ral GTPase-activating protein subunit alpha-1 chr14 GO:0043085 Not Cancer Driver No 227 0.111 649 73 0.112 1
RALGAPA2 RALGAPA2 Q2PPJ7 Ral GTPase-activating protein subunit alpha-2 chr20 GO:0043085 Not Cancer Driver No 243 0.13 415 66 0.159 0
RALGAPB_ENST00000397040 RALGAPB Q86X10 Ral GTPase-activating protein subunit beta chr20 GO:0043085 Not Cancer Driver No 202 0.135 376 54 0.144 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0043085 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0043085 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAP1GAP2 RAP1GAP2 Q684P5 Rap1 GTPase-activating protein 2 chr17 GO:0043085 Not Cancer Driver No 93 0.127 413 57 0.138 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0043085 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0043085 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARRES3 PLAAT4 Q9UL19 Phospholipase A and acyltransferase 4 chr11 GO:0043085 Not Cancer Driver No 25 0.152 7 1 0.143 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0043085 Not Cancer Driver No 226 0.178 332 64 0.193 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0043085 Not Cancer Driver No 96 0.12 191 12 0.063 1
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0043085 Not Cancer Driver No 63 0.121 194 27 0.139 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0043085 Not Cancer Driver No 37 0.185 24 5 0.208 0
RELN RELN P78509 Reelin chr7 GO:0043085 Not Cancer Driver No 761 0.22 107 19 0.178 7
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0043085 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0043085 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0043085 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0043085 Not Cancer Driver No 38 0.112 20 1 0.05 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0043085 Not Cancer Driver No 15 0.097 1 0 0.0 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0043085 Not Cancer Driver No 73 0.23 28 5 0.179 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0043085 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGN RGN Q15493 Regucalcin chrX GO:0043085 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHOG_ENST00000396978 RHOG P84095 Rho-related GTP-binding protein RhoG chr11 GO:0043085 Not Cancer Driver No 26 0.136 22 5 0.227 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0043085 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0043085 Not Cancer Driver No 66 0.127 295 39 0.132 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0043085 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0043085 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0043085 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 GO:0043085 Not Cancer Driver No 34 0.116 85 14 0.165 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0043085 Not Cancer Driver No 22 0.091 48 4 0.083 0
RUNDC1 RUNDC1 Q96C34 RUN domain-containing protein 1 chr17 GO:0043085 Not Cancer Driver No 65 0.106 238 21 0.088 0
S100A1 S100A1 P23297 Protein S100-A1 chr1 GO:0043085 Not Cancer Driver No 13 0.138 9 0 0.0 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0043085 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0043085 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0043085 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SDHAF4 SDHAF4 Q5VUM1 Succinate dehydrogenase assembly factor 4, mitochondrial chr6 GO:0043085 Not Cancer Driver No 14 0.13 76 10 0.132 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0043085 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0043085 Not Cancer Driver No 147 0.253 561 145 0.258 0
SERINC1 SERINC1 Q9NRX5 Serine incorporator 1 chr6 GO:0043085 Not Cancer Driver No 51 0.113 21 1 0.048 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0043085 Not Cancer Driver No 38 0.09 13 1 0.077 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0043085 Not Cancer Driver No 62 0.091 154 12 0.078 0
SGSM1 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0043085 Not Cancer Driver No 206 0.179 418 68 0.163 0
SGSM2_ENST00000426855 SGSM2 O43147 Small G protein signaling modulator 2 chr17 GO:0043085 Not Cancer Driver No 83 0.083 316 21 0.066 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0043085 Not Cancer Driver No 83 0.111 77 9 0.117 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0043085 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SIPA1L2 SIPA1L2 Q9P2F8 Signal-induced proliferation-associated 1-like protein 2 chr1 GO:0043085 Not Cancer Driver No 311 0.181 895 172 0.192 0
SIPA1L3 SIPA1L3 O60292 Signal-induced proliferation-associated 1-like protein 3 chr19 GO:0043085 Not Cancer Driver No 273 0.153 1257 190 0.151 0
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0043085 Not Cancer Driver No 67 0.064 666 43 0.065 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0043085 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0043085 Not Cancer Driver No 33 0.083 60 2 0.033 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0043085 Not Cancer Driver No 19 0.117 95 17 0.179 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0043085 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC27A4 SLC27A4 Q6P1M0 Long-chain fatty acid transport protein 4 chr9 GO:0043085 Not Cancer Driver No 83 0.129 27 3 0.111 5
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0043085 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 GO:0043085 Not Cancer Driver No 81 0.113 73 6 0.082 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0043085 Census, Compendium Yes 97 0.228 111 19 0.171 5
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0043085 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0043085 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0043085 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0043085 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0043085 Not Cancer Driver No 39 0.125 119 11 0.092 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0043085 Census Yes 53 0.099 130 11 0.085 1
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0043085 Not Cancer Driver No 27 0.182 0 0 0.0 6
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0043085 Not Cancer Driver No 330 0.315 820 282 0.344 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0043085 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0043085 Census, Compendium Yes 110 0.143 152 15 0.099 19
STIM1_ENST00000300737 STIM1 Q13586 Stromal interaction molecule 1 chr11 GO:0043085 Not Cancer Driver No 70 0.102 387 45 0.116 13
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0043085 Not Cancer Driver No 121 0.122 659 83 0.126 2
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0043085 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0043085 Not Cancer Driver No 50 0.168 152 20 0.132 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0043085 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYDE2 SYDE2 Q5VT97 Rho GTPase-activating protein SYDE2 chr1 GO:0043085 Not Cancer Driver No 136 0.114 693 69 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0043085 Census Yes 96 0.151 131 27 0.206 5
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0043085 Census Yes 54 0.163 305 53 0.174 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0043085 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0043085 Not Cancer Driver No 123 0.137 494 64 0.13 0
TAX1BP3 TAX1BP3 O14907 Tax1-binding protein 3 chr17 GO:0043085 Not Cancer Driver No 16 0.129 51 8 0.157 0
TBC1D1 TBC1D1 Q86TI0 TBC1 domain family member 1 chr4 GO:0043085 Not Cancer Driver No 138 0.118 455 58 0.127 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0043085 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D10B TBC1D10B Q4KMP7 TBC1 domain family member 10B chr16 GO:0043085 Not Cancer Driver No 54 0.067 498 27 0.054 0
TBC1D10C TBC1D10C Q8IV04 Carabin chr11 GO:0043085 Not Cancer Driver No 58 0.13 192 32 0.167 0
TBC1D12 TBC1D12 O60347 TBC1 domain family member 12 chr10 GO:0043085 Not Cancer Driver No 62 0.08 458 20 0.044 0
TBC1D13 TBC1D13 Q9NVG8 TBC1 domain family member 13 chr9 GO:0043085 Not Cancer Driver No 49 0.122 57 10 0.175 0
TBC1D14 TBC1D14 Q9P2M4 TBC1 domain family member 14 chr4 GO:0043085 Not Cancer Driver No 80 0.115 311 36 0.116 0
TBC1D15 TBC1D15 Q8TC07 TBC1 domain family member 15 chr12 GO:0043085 Not Cancer Driver No 90 0.13 135 23 0.17 0
TBC1D16 TBC1D16 Q8TBP0 TBC1 domain family member 16 chr17 GO:0043085 Not Cancer Driver No 84 0.11 307 37 0.121 0
TBC1D17 TBC1D17 Q9HA65 TBC1 domain family member 17 chr19 GO:0043085 Not Cancer Driver No 76 0.117 191 25 0.131 0
TBC1D2 TBC1D2 Q9BYX2 TBC1 domain family member 2A chr9 GO:0043085 Not Cancer Driver No 106 0.114 338 39 0.115 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0043085 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBC1D22A TBC1D22A Q8WUA7 TBC1 domain family member 22A chr22 GO:0043085 Not Cancer Driver No 84 0.162 219 23 0.105 0
TBC1D22B TBC1D22B Q9NU19 TBC1 domain family member 22B chr6 GO:0043085 Not Cancer Driver No 55 0.109 205 27 0.132 0
TBC1D25 TBC1D25 Q3MII6 TBC1 domain family member 25 chrX GO:0043085 Not Cancer Driver No 114 0.166 256 37 0.145 0
TBC1D26 TBC1D26 Q86UD7 TBC1 domain family member 26 chr17 GO:0043085 Not Cancer Driver No 34 0.136 66 7 0.106 0
TBC1D28 TBC1D28 Q2M2D7 TBC1 domain family member 28 chr17 GO:0043085 Not Cancer Driver No 36 0.171 61 12 0.197 0
TBC1D2B TBC1D2B Q9UPU7 TBC1 domain family member 2B chr15 GO:0043085 Not Cancer Driver No 118 0.123 419 43 0.103 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0043085 Not Cancer Driver No 173 0.133 590 90 0.153 0
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0043085 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0043085 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBC1D8B TBC1D8B Q0IIM8 TBC1 domain family member 8B chrX GO:0043085 Not Cancer Driver No 197 0.176 134 21 0.157 2
TBC1D8_ENST00000376840 TBC1D8 O95759 TBC1 domain family member 8 chr2 GO:0043085 Not Cancer Driver No 164 0.144 224 28 0.125 0
TBC1D9 TBC1D9 Q6ZT07 TBC1 domain family member 9 chr4 GO:0043085 Not Cancer Driver No 196 0.155 295 57 0.193 0
TBC1D9B TBC1D9B Q66K14 TBC1 domain family member 9B chr5 GO:0043085 Not Cancer Driver No 142 0.114 346 34 0.098 0
TBCK_ENST00000432496 TBCK Q8TEA7 TBC domain-containing protein kinase-like protein chr4 GO:0043085 Not Cancer Driver No 115 0.129 88 9 0.102 2
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0043085 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0043085 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0043085 Not Cancer Driver No 219 0.195 126 22 0.175 10
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0043085 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0043085 Census Yes 110 0.097 212 16 0.075 31
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0043085 Compendium Yes 61 0.18 285 52 0.182 0
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0043085 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0043085 Not Cancer Driver No 41 0.105 41 4 0.098 10
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0043085 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIAM2 TIAM2 Q8IVF5 Rho guanine nucleotide exchange factor TIAM2 chr6 GO:0043085 Not Cancer Driver No 309 0.182 779 166 0.213 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0043085 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0043085 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0043085 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0043085 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0043085 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0043085 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0043085 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP8L3 TNFAIP8L3 Q5GJ75 Tumor necrosis factor alpha-induced protein 8-like protein 3 chr15 GO:0043085 Not Cancer Driver No 40 0.137 111 12 0.108 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0043085 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0043085 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0043085 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0043085 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0043085 Not Cancer Driver No 163 0.123 480 59 0.123 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0043085 Not Cancer Driver No 149 0.143 795 105 0.132 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0043085 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0043085 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0043085 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0043085 Not Cancer Driver No 65 0.182 114 24 0.211 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0043085 Census, Compendium Yes 135 0.116 732 78 0.107 11
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0043085 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TXN TXN P10599 Thioredoxin chr9 GO:0043085 Not Cancer Driver No 6 0.057 0 0 0.0 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0043085 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0043085 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0043085 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0043085 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0043085 Not Cancer Driver No 25 0.113 102 12 0.118 0
UCN UCN P55089 Urocortin chr2 GO:0043085 Not Cancer Driver No 7 0.056 61 4 0.066 0
UHRF1_ENST00000616255 UHRF1 Q96T88 E3 ubiquitin-protein ligase UHRF1 chr19 GO:0043085 Not Cancer Driver No 97 0.122 353 49 0.139 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0043085 Not Cancer Driver No 20 0.083 89 4 0.045 1
USP6 USP6 P35125 Ubiquitin carboxyl-terminal hydrolase 6 chr17 GO:0043085 Census, Compendium Yes 243 0.173 537 83 0.155 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 GO:0043085 Not Cancer Driver No 113 0.136 472 81 0.172 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0043085 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0043085 Not Cancer Driver No 153 0.181 102 18 0.176 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0043085 Not Cancer Driver No 88 0.109 186 16 0.086 16
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0043085 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0043085 Not Cancer Driver No 27 0.116 41 7 0.171 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0043085 Not Cancer Driver No 65 0.137 180 18 0.1 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0043085 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0043085 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT9B WNT9B O14905 Protein Wnt-9b chr17 GO:0043085 Not Cancer Driver No 47 0.132 11 4 0.364 0
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0043085 Not Cancer Driver No 66 0.12 232 29 0.125 4
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0043085 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0043085 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0043085 Not Cancer Driver No 87 0.119 118 11 0.093 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 GO:0043085 Not Cancer Driver No 22 0.089 109 4 0.037 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0043085 Not Cancer Driver No 85 0.149 383 55 0.144 0