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Total number of protein in "GO:0042752" GO term:  116

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0042752 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0042752 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0042752 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRB1 ADRB1 P08588 Beta-1 adrenergic receptor chr10 GO:0042752 Not Cancer Driver No 35 0.073 116 1 0.009 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0042752 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARNTL2 ARNTL2 Q8WYA1 Aryl hydrocarbon receptor nuclear translocator-like protein 2 chr12 GO:0042752 Not Cancer Driver No 79 0.124 264 38 0.144 0
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0042752 Compendium Yes 77 0.11 53 8 0.151 6
ATOH7 ATOH7 Q8N100 Transcription factor ATOH7 chr10 GO:0042752 Not Cancer Driver No 10 0.066 40 3 0.075 2
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0042752 Not Cancer Driver No 52 0.126 242 31 0.128 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0042752 Not Cancer Driver No 80 0.132 45 4 0.089 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0042752 Not Cancer Driver No 102 0.111 528 62 0.117 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0042752 Not Cancer Driver No 40 0.135 1 0 0.0 0
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0042752 Not Cancer Driver No 92 0.183 23 2 0.087 2
CIPC CIPC Q9C0C6 CLOCK-interacting pacemaker chr14 GO:0042752 Not Cancer Driver No 43 0.108 354 41 0.116 0
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0042752 Not Cancer Driver No 83 0.098 458 38 0.083 0
CRH CRH P06850 Corticoliberin chr8 GO:0042752 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0042752 Census, Compendium Yes 63 0.099 606 62 0.102 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0042752 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0042752 Not Cancer Driver No 72 0.121 100 12 0.12 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0042752 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0042752 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0042752 Not Cancer Driver No 62 0.149 133 18 0.135 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0042752 Not Cancer Driver No 126 0.111 50 8 0.16 4
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0042752 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0042752 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0042752 Not Cancer Driver No 26 0.062 109 0 0.0 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0042752 Census, Compendium Yes 120 0.161 284 44 0.155 11
FBXL12 FBXL12 Q9NXK8 F-box/LRR-repeat protein 12 chr19 GO:0042752 Not Cancer Driver No 41 0.126 0 0 0.0 0
FBXL17 FBXL17 Q9UF56 F-box/LRR-repeat protein 17 chr5 GO:0042752 Not Cancer Driver No 58 0.083 194 1 0.005 0
FBXL22 FBXL22 Q6P050 F-box and leucine-rich protein 22 chr15 GO:0042752 Not Cancer Driver No 15 0.061 125 3 0.024 0
FBXL3 FBXL3 Q9UKT7 F-box/LRR-repeat protein 3 chr13 GO:0042752 Not Cancer Driver No 49 0.114 30 6 0.2 1
FBXL6 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 GO:0042752 Not Cancer Driver No 48 0.089 114 5 0.044 0
FBXL8 FBXL8 Q96CD0 F-box/LRR-repeat protein 8 chr16 GO:0042752 Not Cancer Driver No 19 0.051 7 0 0.0 0
FBXW11 FBXW11 Q9UKB1 F-box/WD repeat-containing protein 11 chr5 GO:0042752 Not Cancer Driver No 75 0.138 20 3 0.15 7
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0042752 Census, Compendium Yes 322 0.455 230 38 0.165 0
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0042752 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0042752 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0042752 Not Cancer Driver No 20 0.171 52 11 0.212 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 GO:0042752 Census, Compendium Yes 48 0.134 10 0 0.0 5
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 GO:0042752 Census, Compendium Yes 57 0.159 14 1 0.071 1
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0042752 Not Cancer Driver No 56 0.133 146 13 0.089 0
HCRTR2 HCRTR2 O43614 Orexin receptor type 2 chr6 GO:0042752 Not Cancer Driver No 154 0.347 38 13 0.342 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0042752 Not Cancer Driver No 65 0.152 61 8 0.131 0
HNF4A HNF4A P41235 Hepatocyte nuclear factor 4-alpha chr20 GO:0042752 Not Cancer Driver No 135 0.285 127 48 0.378 5
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0042752 Not Cancer Driver No 39 0.11 206 19 0.092 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0042752 Not Cancer Driver No 14 0.104 52 7 0.135 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0042752 Not Cancer Driver No 96 0.192 82 16 0.195 5
KDM2A KDM2A Q9Y2K7 Lysine-specific demethylase 2A chr11 GO:0042752 Not Cancer Driver No 131 0.113 387 48 0.124 0
KLF10 KLF10 Q13118 Krueppel-like factor 10 chr8 GO:0042752 Not Cancer Driver No 59 0.123 349 46 0.132 0
MAGED1_ENST00000326587 MAGED1 Q9Y5V3 Melanoma-associated antigen D1 chrX GO:0042752 Not Cancer Driver No 131 0.168 457 71 0.155 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 GO:0042752 Not Cancer Driver No 178 0.143 1010 118 0.117 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0042752 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0042752 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0042752 Not Cancer Driver No 59 0.139 90 8 0.089 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:0042752 Not Cancer Driver No 92 0.129 327 42 0.128 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0042752 Not Cancer Driver No 104 0.287 8 1 0.125 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0042752 Census, Compendium Yes 379 0.149 296 37 0.125 18
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0042752 Census, Compendium Yes 41 0.111 334 39 0.117 7
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0042752 Not Cancer Driver No 214 0.248 248 61 0.246 4
NOCT NOCT Q9UK39 Nocturnin chr4 GO:0042752 Not Cancer Driver No 33 0.077 89 3 0.034 0
NONO NONO Q15233 Non-POU domain-containing octamer-binding protein chrX GO:0042752 Census, Compendium Yes 101 0.214 349 64 0.183 0
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0042752 Not Cancer Driver No 27 0.303 5 2 0.4 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0042752 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1D2 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 GO:0042752 Not Cancer Driver No 76 0.131 223 25 0.112 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0042752 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR2F6 NR2F6 P10588 Nuclear receptor subfamily 2 group F member 6 chr19 GO:0042752 Not Cancer Driver No 25 0.062 70 4 0.057 0
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0042752 Not Cancer Driver No 39 0.097 6 1 0.167 0
OPN4_ENST00000241891 OPN4 Q9UHM6 Melanopsin chr10 GO:0042752 Not Cancer Driver No 84 0.176 88 9 0.102 0
OPN5 OPN5 Q6U736 Opsin-5 chr6 GO:0042752 Not Cancer Driver No 65 0.184 0 0 0.0 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0042752 Not Cancer Driver No 81 0.219 0 0 0.0 0
PASD1 PASD1 Q8IV76 Circadian clock protein PASD1 chrX GO:0042752 Not Cancer Driver No 223 0.288 545 157 0.288 0
PDE6B PDE6B P35913 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta chr4 GO:0042752 Not Cancer Driver No 144 0.169 44 9 0.205 13
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0042752 Census Yes 160 0.124 948 116 0.122 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0042752 Not Cancer Driver No 166 0.132 782 101 0.129 1
PER3_ENST00000361923 PER3 P56645 Period circadian protein homolog 3 chr1 GO:0042752 Not Cancer Driver No 170 0.142 710 100 0.141 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:0042752 Not Cancer Driver No 134 0.078 744 29 0.039 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0042752 Not Cancer Driver No 138 0.142 232 38 0.164 0
PML PML P29590 Protein PML chr15 GO:0042752 Census, Compendium Yes 112 0.127 312 34 0.109 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0042752 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0042752 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0042752 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0042752 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0042752 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0042752 Not Cancer Driver No 26 0.08 23 4 0.174 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0042752 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0042752 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0042752 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0042752 Not Cancer Driver No 538 0.13 421 61 0.145 2
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0042752 Not Cancer Driver No 182 0.247 537 141 0.263 0
PSPC1_ENST00000619300 PSPC1 Q8WXF1 Paraspeckle component 1 chr13 GO:0042752 Not Cancer Driver No 97 0.185 367 81 0.221 0
PTGDS PTGDS P41222 Prostaglandin-H2 D-isomerase chr9 GO:0042752 Not Cancer Driver No 31 0.163 13 3 0.231 0
RBM4B_ENST00000310046 RBM4B Q9BQ04 RNA-binding protein 4B chr11 GO:0042752 Not Cancer Driver No 47 0.131 126 19 0.151 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0042752 Not Cancer Driver No 40 0.11 129 12 0.093 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0042752 Not Cancer Driver No 145 0.104 732 81 0.111 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0042752 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORB_ENST00000396204 RORB Q92753 Nuclear receptor ROR-beta chr9 GO:0042752 Not Cancer Driver No 107 0.228 87 22 0.253 1
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0042752 Not Cancer Driver No 96 0.185 187 36 0.193 1
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0042752 Census Yes 59 0.083 595 48 0.081 0
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0042752 Not Cancer Driver No 48 0.148 68 3 0.044 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0042752 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0042752 Compendium Yes 172 0.135 617 73 0.118 0
SOX14 SOX14 O95416 Transcription factor SOX-14 chr3 GO:0042752 Not Cancer Driver No 48 0.2 128 32 0.25 0
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 GO:0042752 Not Cancer Driver No 42 0.154 75 3 0.04 0
SRRD SRRD Q9UH36 SRR1-like protein chr22 GO:0042752 Not Cancer Driver No 30 0.088 64 3 0.047 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0042752 Not Cancer Driver No 59 0.143 15 1 0.067 0
SUV39H2 SUV39H2 Q9H5I1 Histone-lysine N-methyltransferase SUV39H2 chr10 GO:0042752 Not Cancer Driver No 39 0.095 23 1 0.043 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0042752 Not Cancer Driver No 51 0.123 202 15 0.074 27
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 GO:0042752 Census Yes 137 0.143 955 137 0.143 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0042752 Not Cancer Driver No 154 0.127 367 51 0.139 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0042752 Compendium Yes 150 0.098 508 59 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0042752 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0042752 Not Cancer Driver No 141 0.161 136 22 0.162 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 GO:0042752 Not Cancer Driver No 88 0.145 213 39 0.183 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0042752 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0042752 Census, Compendium Yes 339 0.133 405 51 0.126 1
ZFHX3_ENST00000268489 ZFHX3 Q15911 Zinc finger homeobox protein 3 chr16 GO:0042752 Census, Compendium Yes 501 0.135 2555 337 0.132 0