Total number of protein in "GO:0035303" GO term: 101
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AC011195.2 | IGBP1P2 | A0A1W2PR95 | HCG1642624, isoform CRA_a | chr17 | GO:0035303 | Not Cancer Driver | No | 6 | 0.018 | 201 | 4 | 0.02 | 0 |
| ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0035303 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
| AGTR2 | AGTR2 | P50052 | Type-2 angiotensin II receptor | chrX | GO:0035303 | Not Cancer Driver | No | 98 | 0.27 | 0 | 0 | 0.0 | 0 |
| AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0035303 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
| ANKLE2 | ANKLE2 | Q86XL3 | Ankyrin repeat and LEM domain-containing protein 2 | chr12 | GO:0035303 | Not Cancer Driver | No | 127 | 0.135 | 521 | 71 | 0.136 | 2 |
| BAG4 | BAG4 | O95429 | BAG family molecular chaperone regulator 4 | chr8 | GO:0035303 | Not Cancer Driver | No | 55 | 0.12 | 402 | 49 | 0.122 | 0 |
| BMP2 | BMP2 | P12643 | Bone morphogenetic protein 2 | chr20 | GO:0035303 | Not Cancer Driver | No | 73 | 0.184 | 139 | 26 | 0.187 | 0 |
| BOD1 | BOD1 | Q96IK1 | Biorientation of chromosomes in cell division protein 1 | chr5 | GO:0035303 | Not Cancer Driver | No | 16 | 0.086 | 133 | 10 | 0.075 | 0 |
| BOD1L1 | BOD1L1 | Q8NFC6 | Biorientation of chromosomes in cell division protein 1-like 1 | chr4 | GO:0035303 | Not Cancer Driver | No | 387 | 0.127 | 3023 | 384 | 0.127 | 0 |
| BOD1L2 | BOD1L2 | Q8IYS8 | Biorientation of chromosomes in cell division protein 1-like 2 | chr18 | GO:0035303 | Not Cancer Driver | No | 29 | 0.169 | 144 | 26 | 0.181 | 0 |
| CALM1 | CALM1 | P0DP23 | Calmodulin-1 | chr14 | GO:0035303 | Not Cancer Driver | No | 19 | 0.128 | 115 | 15 | 0.13 | 7 |
| CALM2 | CALM2 | P0DP24 | Calmodulin-2 | chr2 | GO:0035303 | Not Cancer Driver | No | 18 | 0.121 | 115 | 13 | 0.113 | 8 |
| CALM3_ENST00000596362 | CALM3 | P0DP25 | Calmodulin-3 | chr19 | GO:0035303 | Not Cancer Driver | No | 17 | 0.114 | 115 | 10 | 0.087 | 3 |
| CAMTA1 | CAMTA1 | Q9Y6Y1 | Calmodulin-binding transcription activator 1 | chr1 | GO:0035303 | Census, Compendium | Yes | 300 | 0.179 | 883 | 152 | 0.172 | 0 |
| CD300A | CD300A | Q9UGN4 | CMRF35-like molecule 8 | chr17 | GO:0035303 | Not Cancer Driver | No | 53 | 0.177 | 70 | 10 | 0.143 | 0 |
| CD33 | CD33 | P20138 | Myeloid cell surface antigen CD33 | chr19 | GO:0035303 | Not Cancer Driver | No | 119 | 0.327 | 177 | 50 | 0.282 | 0 |
| CDCA2 | CDCA2 | Q69YH5 | Cell division cycle-associated protein 2 | chr8 | GO:0035303 | Not Cancer Driver | No | 124 | 0.121 | 828 | 100 | 0.121 | 0 |
| CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0035303 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
| CHP2 | CHP2 | O43745 | Calcineurin B homologous protein 2 | chr16 | GO:0035303 | Not Cancer Driver | No | 43 | 0.219 | 65 | 16 | 0.246 | 0 |
| CHRM5 | CHRM5 | P08912 | Muscarinic acetylcholine receptor M5 | chr15 | GO:0035303 | Not Cancer Driver | No | 74 | 0.139 | 155 | 20 | 0.129 | 0 |
| CNEP1R1_ENST00000427478 | CNEP1R1 | Q8N9A8 | Nuclear envelope phosphatase-regulatory subunit 1 | chr16 | GO:0035303 | Not Cancer Driver | No | 8 | 0.064 | 0 | 0 | 0.0 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0035303 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| CSNK2B_ENST00000375866 | CSNK2B | P67870 | Casein kinase II subunit beta | chr6 | GO:0035303 | Not Cancer Driver | No | 20 | 0.093 | 19 | 0 | 0.0 | 4 |
| DLC1 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0035303 | Not Cancer Driver | No | 331 | 0.217 | 922 | 237 | 0.257 | 0 |
| FCRL3_ENST00000368184 | FCRL3 | Q96P31 | Fc receptor-like protein 3 | chr1 | GO:0035303 | Not Cancer Driver | No | 193 | 0.263 | 217 | 44 | 0.203 | 0 |
| FKBP1A | FKBP1A | P62942 | Peptidyl-prolyl cis-trans isomerase FKBP1A | chr20 | GO:0035303 | Not Cancer Driver | No | 15 | 0.139 | 39 | 7 | 0.179 | 0 |
| FKBP1B | FKBP1B | P68106 | Peptidyl-prolyl cis-trans isomerase FKBP1B | chr2 | GO:0035303 | Not Cancer Driver | No | 10 | 0.093 | 58 | 4 | 0.069 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0035303 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GNA12 | GNA12 | Q03113 | Guanine nucleotide-binding protein subunit alpha-12 | chr7 | GO:0035303 | Not Cancer Driver | No | 41 | 0.108 | 20 | 0 | 0.0 | 0 |
| GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | GO:0035303 | Compendium | Yes | 50 | 0.141 | 24 | 0 | 0.0 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0035303 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0035303 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0035303 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
| IFNG | IFNG | P01579 | Interferon gamma | chr12 | GO:0035303 | Not Cancer Driver | No | 51 | 0.307 | 23 | 6 | 0.261 | 0 |
| IGBP1_ENST00000356413 | IGBP1 | P78318 | Immunoglobulin-binding protein 1 | chrX | GO:0035303 | Not Cancer Driver | No | 51 | 0.15 | 193 | 28 | 0.145 | 0 |
| IKBKB | IKBKB | O14920 | Inhibitor of nuclear factor kappa-B kinase subunit beta | chr8 | GO:0035303 | Census, Compendium | Yes | 106 | 0.14 | 211 | 31 | 0.147 | 1 |
| ITGA1 | ITGA1 | P56199 | Integrin alpha-1 | chr5 | GO:0035303 | Not Cancer Driver | No | 156 | 0.132 | 107 | 13 | 0.121 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0035303 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0035303 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| LGALS3 | LGALS3 | P17931 | Galectin-3 | chr14 | GO:0035303 | Not Cancer Driver | No | 15 | 0.06 | 133 | 6 | 0.045 | 0 |
| LILRB2_ENST00000314446 | LILRB2 | Q8N423 | Leukocyte immunoglobulin-like receptor subfamily B member 2 | chr19 | GO:0035303 | Not Cancer Driver | No | 148 | 0.248 | 235 | 50 | 0.213 | 0 |
| LPIN1_ENST00000256720 | LPIN1 | Q14693 | Phosphatidate phosphatase LPIN1 | chr2 | GO:0035303 | Not Cancer Driver | No | 120 | 0.135 | 447 | 70 | 0.157 | 0 |
| MAGI2 | MAGI2 | Q86UL8 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | chr7 | GO:0035303 | Not Cancer Driver | No | 305 | 0.21 | 1086 | 201 | 0.185 | 0 |
| MASTL | MASTL | Q96GX5 | Serine/threonine-protein kinase greatwall | chr10 | GO:0035303 | Not Cancer Driver | No | 90 | 0.102 | 389 | 44 | 0.113 | 0 |
| MEF2C_ENST00000504921 | MEF2C | Q06413 | Myocyte-specific enhancer factor 2C | chr5 | GO:0035303 | Not Cancer Driver | No | 92 | 0.195 | 408 | 81 | 0.199 | 0 |
| MGAT5_ENST00000281923 | MGAT5 | Q09328 | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A | chr2 | GO:0035303 | Not Cancer Driver | No | 106 | 0.143 | 24 | 2 | 0.083 | 0 |
| MTMR1_ENST00000370390 | MTMR1 | Q13613 | Myotubularin-related protein 1 | chrX | GO:0035303 | Not Cancer Driver | No | 114 | 0.171 | 146 | 21 | 0.144 | 0 |
| MTMR2 | MTMR2 | Q13614 | Myotubularin-related protein 2 | chr11 | GO:0035303 | Not Cancer Driver | No | 70 | 0.109 | 140 | 16 | 0.114 | 1 |
| MTMR3 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0035303 | Not Cancer Driver | No | 130 | 0.109 | 501 | 66 | 0.132 | 0 |
| MTMR4 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0035303 | Not Cancer Driver | No | 147 | 0.123 | 474 | 59 | 0.124 | 0 |
| MTMR9 | MTMR9 | Q96QG7 | Myotubularin-related protein 9 | chr8 | GO:0035303 | Not Cancer Driver | No | 60 | 0.109 | 45 | 7 | 0.156 | 0 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0035303 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| NCKAP1L | NCKAP1L | P55160 | Nck-associated protein 1-like | chr12 | GO:0035303 | Not Cancer Driver | No | 247 | 0.219 | 51 | 10 | 0.196 | 4 |
| NPNT_ENST00000379987 | NPNT | Q6UXI9 | Nephronectin | chr4 | GO:0035303 | Not Cancer Driver | No | 90 | 0.159 | 218 | 33 | 0.151 | 0 |
| NSMF | NSMF | Q6X4W1 | NMDA receptor synaptonuclear signaling and neuronal migration factor | chr9 | GO:0035303 | Not Cancer Driver | No | 46 | 0.087 | 287 | 19 | 0.066 | 2 |
| NUAK1 | NUAK1 | O60285 | NUAK family SNF1-like kinase 1 | chr12 | GO:0035303 | Not Cancer Driver | No | 142 | 0.215 | 357 | 77 | 0.216 | 0 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0035303 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0035303 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0035303 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PLEK | PLEK | P08567 | Pleckstrin | chr2 | GO:0035303 | Not Cancer Driver | No | 81 | 0.231 | 39 | 9 | 0.231 | 0 |
| PPARGC1B | PPARGC1B | Q86YN6 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta | chr5 | GO:0035303 | Not Cancer Driver | No | 125 | 0.122 | 845 | 99 | 0.117 | 0 |
| PPIA | PPIA | P62937 | Peptidyl-prolyl cis-trans isomerase A | chr7 | GO:0035303 | Not Cancer Driver | No | 11 | 0.067 | 24 | 3 | 0.125 | 0 |
| PPP1R11 | PPP1R11 | O60927 | E3 ubiquitin-protein ligase PPP1R11 | chr6 | GO:0035303 | Not Cancer Driver | No | 17 | 0.135 | 126 | 17 | 0.135 | 0 |
| PPP1R12A_ENST00000261207 | PPP1R12A | O14974 | Protein phosphatase 1 regulatory subunit 12A | chr12 | GO:0035303 | Not Cancer Driver | No | 107 | 0.104 | 821 | 89 | 0.108 | 0 |
| PPP1R14D_ENST00000299174 | PPP1R14D | Q9NXH3 | Protein phosphatase 1 regulatory subunit 14D | chr15 | GO:0035303 | Not Cancer Driver | No | 10 | 0.069 | 119 | 10 | 0.084 | 0 |
| PPP1R15A | PPP1R15A | O75807 | Protein phosphatase 1 regulatory subunit 15A | chr19 | GO:0035303 | Not Cancer Driver | No | 83 | 0.123 | 628 | 72 | 0.115 | 0 |
| PPP1R15B | PPP1R15B | Q5SWA1 | Protein phosphatase 1 regulatory subunit 15B | chr1 | GO:0035303 | Not Cancer Driver | No | 72 | 0.101 | 415 | 45 | 0.108 | 1 |
| PPP1R16B | PPP1R16B | Q96T49 | Protein phosphatase 1 regulatory inhibitor subunit 16B | chr20 | GO:0035303 | Not Cancer Driver | No | 132 | 0.233 | 220 | 66 | 0.3 | 0 |
| PPP1R1B | PPP1R1B | Q9UD71 | Protein phosphatase 1 regulatory subunit 1B | chr17 | GO:0035303 | Not Cancer Driver | No | 30 | 0.147 | 204 | 30 | 0.147 | 0 |
| PPP1R7 | PPP1R7 | Q15435 | Protein phosphatase 1 regulatory subunit 7 | chr2 | GO:0035303 | Not Cancer Driver | No | 46 | 0.128 | 78 | 16 | 0.205 | 0 |
| PPP1R9B | PPP1R9B | Q96SB3 | Neurabin-2 | chr17 | GO:0035303 | Not Cancer Driver | No | 47 | 0.058 | 695 | 35 | 0.05 | 0 |
| PPP2R3C | PPP2R3C | Q969Q6 | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma | chr14 | GO:0035303 | Not Cancer Driver | No | 44 | 0.097 | 30 | 3 | 0.1 | 0 |
| PPP2R5A | PPP2R5A | Q15172 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform | chr1 | GO:0035303 | Not Cancer Driver | No | 55 | 0.113 | 93 | 5 | 0.054 | 0 |
| PPP2R5D | PPP2R5D | Q14738 | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform | chr6 | GO:0035303 | Not Cancer Driver | No | 64 | 0.106 | 178 | 13 | 0.073 | 4 |
| PPP4R4 | PPP4R4 | Q6NUP7 | Serine/threonine-protein phosphatase 4 regulatory subunit 4 | chr14 | GO:0035303 | Not Cancer Driver | No | 164 | 0.188 | 209 | 43 | 0.206 | 0 |
| PRKCD_ENST00000330452 | PRKCD | Q05655 | Protein kinase C delta type | chr3 | GO:0035303 | Compendium | Yes | 79 | 0.117 | 43 | 9 | 0.209 | 0 |
| PTBP1_ENST00000349038 | PTBP1 | P26599 | Polypyrimidine tract-binding protein 1 | chr19 | GO:0035303 | Not Cancer Driver | No | 74 | 0.139 | 154 | 17 | 0.11 | 0 |
| PTPA_ENST00000337738 | PTPA | Q15257 | Serine/threonine-protein phosphatase 2A activator | chr9 | GO:0035303 | Not Cancer Driver | No | 40 | 0.112 | 63 | 2 | 0.032 | 0 |
| PTPRC | PTPRC | P08575 | Receptor-type tyrosine-protein phosphatase C | chr1 | GO:0035303 | Census, Compendium | Yes | 315 | 0.241 | 462 | 107 | 0.232 | 0 |
| RGN | RGN | Q15493 | Regucalcin | chrX | GO:0035303 | Not Cancer Driver | No | 38 | 0.127 | 14 | 3 | 0.214 | 0 |
| RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | GO:0035303 | Not Cancer Driver | No | 66 | 0.127 | 295 | 39 | 0.132 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0035303 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0035303 | Not Cancer Driver | No | 145 | 0.104 | 732 | 81 | 0.111 | 0 |
| SEMA4D | SEMA4D | Q92854 | Semaphorin-4D | chr9 | GO:0035303 | Not Cancer Driver | No | 117 | 0.136 | 132 | 15 | 0.114 | 0 |
| SLC39A10_ENST00000359634 | SLC39A10 | Q9ULF5 | Zinc transporter ZIP10 | chr2 | GO:0035303 | Not Cancer Driver | No | 111 | 0.134 | 417 | 63 | 0.151 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0035303 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMG5 | SMG5 | Q9UPR3 | Nonsense-mediated mRNA decay factor SMG5 | chr1 | GO:0035303 | Not Cancer Driver | No | 132 | 0.13 | 295 | 51 | 0.173 | 0 |
| SMG6 | SMG6 | Q86US8 | Telomerase-binding protein EST1A | chr17 | GO:0035303 | Not Cancer Driver | No | 166 | 0.117 | 751 | 97 | 0.129 | 0 |
| SMG7_ENST00000347615 | SMG7 | Q92540 | Nonsense-mediated mRNA decay factor SMG7 | chr1 | GO:0035303 | Not Cancer Driver | No | 134 | 0.118 | 664 | 82 | 0.123 | 0 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0035303 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| SPPL3 | SPPL3 | Q8TCT6 | Signal peptide peptidase-like 3 | chr12 | GO:0035303 | Not Cancer Driver | No | 45 | 0.117 | 23 | 0 | 0.0 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0035303 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| STYXL1_ENST00000359697 | STYXL1 | Q9Y6J8 | Serine/threonine/tyrosine-interacting-like protein 1 | chr7 | GO:0035303 | Not Cancer Driver | No | 55 | 0.176 | 18 | 3 | 0.167 | 0 |
| SWAP70 | SWAP70 | Q9UH65 | Switch-associated protein 70 | chr11 | GO:0035303 | Not Cancer Driver | No | 44 | 0.075 | 271 | 18 | 0.066 | 0 |
| SYMPK | SYMPK | Q92797 | Symplekin | chr19 | GO:0035303 | Not Cancer Driver | No | 156 | 0.122 | 398 | 42 | 0.106 | 0 |
| TGFB1 | TGFB1 | P01137 | Transforming growth factor beta-1 proprotein | chr19 | GO:0035303 | Not Cancer Driver | No | 41 | 0.105 | 41 | 4 | 0.098 | 10 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0035303 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TIPRL | TIPRL | O75663 | TIP41-like protein | chr1 | GO:0035303 | Not Cancer Driver | No | 25 | 0.092 | 25 | 3 | 0.12 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0035303 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| VRK3_ENST00000594948 | VRK3 | Q8IV63 | Inactive serine/threonine-protein kinase VRK3 | chr19 | GO:0035303 | Not Cancer Driver | No | 65 | 0.137 | 180 | 18 | 0.1 | 0 |
| YWHAE | YWHAE | P62258 | 14-3-3 protein epsilon | chr17 | GO:0035303 | Census | Yes | 32 | 0.125 | 41 | 3 | 0.073 | 0 |