Total number of protein in "GO:0035295" GO term: 140
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0035295 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0035295 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| ADGRG1 | ADGRG1 | Q9Y653 | Adhesion G-protein coupled receptor G1 | chr16 | GO:0035295 | Not Cancer Driver | No | 64 | 0.092 | 67 | 4 | 0.06 | 9 |
| AHI1_ENST00000457866 | AHI1 | Q8N157 | Jouberin | chr6 | GO:0035295 | Not Cancer Driver | No | 120 | 0.1 | 500 | 56 | 0.112 | 6 |
| AKR1B1 | AKR1B1 | P15121 | Aldo-keto reductase family 1 member B1 | chr7 | GO:0035295 | Not Cancer Driver | No | 52 | 0.165 | 19 | 1 | 0.053 | 0 |
| ALDH1A2 | ALDH1A2 | O94788 | Retinal dehydrogenase 2 | chr15 | GO:0035295 | Not Cancer Driver | No | 100 | 0.193 | 56 | 13 | 0.232 | 0 |
| ALX4 | ALX4 | Q9H161 | Homeobox protein aristaless-like 4 | chr11 | GO:0035295 | Not Cancer Driver | No | 98 | 0.238 | 320 | 77 | 0.241 | 4 |
| AQP11 | AQP11 | Q8NBQ7 | Aquaporin-11 | chr11 | GO:0035295 | Not Cancer Driver | No | 23 | 0.085 | 0 | 0 | 0.0 | 0 |
| AQP2 | AQP2 | P41181 | Aquaporin-2 | chr12 | GO:0035295 | Not Cancer Driver | No | 52 | 0.192 | 31 | 3 | 0.097 | 28 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0035295 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| ARG2 | ARG2 | P78540 | Arginase-2, mitochondrial | chr14 | GO:0035295 | Not Cancer Driver | No | 25 | 0.071 | 58 | 3 | 0.052 | 0 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0035295 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| ATRX | ATRX | P46100 | Transcriptional regulator ATRX | chrX | GO:0035295 | Census, Compendium | Yes | 487 | 0.195 | 1672 | 301 | 0.18 | 33 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0035295 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMP7 | BMP7 | P18075 | Bone morphogenetic protein 7 | chr20 | GO:0035295 | Not Cancer Driver | No | 91 | 0.211 | 69 | 18 | 0.261 | 0 |
| BMPER | BMPER | Q8N8U9 | BMP-binding endothelial regulator protein | chr7 | GO:0035295 | Not Cancer Driver | No | 196 | 0.286 | 0 | 0 | 0.0 | 1 |
| BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0035295 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
| CALB1 | CALB1 | P05937 | Calbindin | chr8 | GO:0035295 | Not Cancer Driver | No | 46 | 0.176 | 0 | 0 | 0.0 | 0 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0035295 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CCKBR | CCKBR | P32239 | Gastrin/cholecystokinin type B receptor | chr11 | GO:0035295 | Not Cancer Driver | No | 122 | 0.273 | 61 | 22 | 0.361 | 0 |
| CER1 | CER1 | O95813 | Cerberus | chr9 | GO:0035295 | Not Cancer Driver | No | 70 | 0.262 | 119 | 27 | 0.227 | 0 |
| CHD8_ENST00000643469 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0035295 | Not Cancer Driver | No | 328 | 0.127 | 1411 | 148 | 0.105 | 0 |
| CLDN18 | CLDN18 | P56856 | Claudin-18 | chr3 | GO:0035295 | Not Cancer Driver | No | 44 | 0.169 | 21 | 5 | 0.238 | 0 |
| CLMP | CLMP | Q9H6B4 | CXADR-like membrane protein | chr11 | GO:0035295 | Not Cancer Driver | No | 53 | 0.142 | 144 | 26 | 0.181 | 1 |
| COBL_ENST00000265136 | COBL | O75128 | Protein cordon-bleu | chr7 | GO:0035295 | Not Cancer Driver | No | 233 | 0.185 | 1149 | 216 | 0.188 | 0 |
| COL2A1 | COL2A1 | P02458 | Collagen alpha-1(II) chain | chr12 | GO:0035295 | Census | Yes | 258 | 0.174 | 1215 | 207 | 0.17 | 64 |
| COL3A1 | COL3A1 | P02461 | Collagen alpha-1(III) chain | chr2 | GO:0035295 | Census | Yes | 402 | 0.274 | 1182 | 337 | 0.285 | 103 |
| CPS1_ENST00000233072 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | GO:0035295 | Not Cancer Driver | No | 368 | 0.245 | 73 | 22 | 0.301 | 140 |
| CRLF1 | CRLF1 | O75462 | Cytokine receptor-like factor 1 | chr19 | GO:0035295 | Not Cancer Driver | No | 51 | 0.121 | 101 | 7 | 0.069 | 14 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0035295 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| CXCL8 | CXCL8 | P10145 | Interleukin-8 | chr4 | GO:0035295 | Not Cancer Driver | No | 17 | 0.172 | 0 | 0 | 0.0 | 0 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0035295 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| DACT2 | DACT2 | Q5SW24 | Dapper homolog 2 | chr6 | GO:0035295 | Not Cancer Driver | No | 35 | 0.045 | 655 | 30 | 0.046 | 0 |
| DCHS1 | DCHS1 | Q96JQ0 | Protocadherin-16 | chr11 | GO:0035295 | Not Cancer Driver | No | 444 | 0.135 | 2197 | 317 | 0.144 | 3 |
| DLG5 | DLG5 | Q8TDM6 | Disks large homolog 5 | chr10 | GO:0035295 | Not Cancer Driver | No | 230 | 0.12 | 1119 | 135 | 0.121 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0035295 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
| EPCAM | EPCAM | P16422 | Epithelial cell adhesion molecule | chr2 | GO:0035295 | Not Cancer Driver | No | 40 | 0.127 | 25 | 2 | 0.08 | 1 |
| FGF9 | FGF9 | P31371 | Fibroblast growth factor 9 | chr13 | GO:0035295 | Not Cancer Driver | No | 41 | 0.197 | 43 | 10 | 0.233 | 1 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0035295 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FOXC1_ENST00000645831 | FOXC1 | Q12948 | Forkhead box protein C1 | chr6 | GO:0035295 | Not Cancer Driver | No | 33 | 0.06 | 411 | 24 | 0.058 | 32 |
| FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0035295 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
| FOXF1 | FOXF1 | Q12946 | Forkhead box protein F1 | chr16 | GO:0035295 | Not Cancer Driver | No | 56 | 0.148 | 194 | 20 | 0.103 | 20 |
| FOXF2 | FOXF2 | Q12947 | Forkhead box protein F2 | chr6 | GO:0035295 | Not Cancer Driver | No | 44 | 0.099 | 277 | 10 | 0.036 | 0 |
| FOXJ1 | FOXJ1 | Q92949 | Forkhead box protein J1 | chr17 | GO:0035295 | Not Cancer Driver | No | 25 | 0.059 | 279 | 18 | 0.065 | 0 |
| GATA2_ENST00000487848 | GATA2 | P23769 | Endothelial transcription factor GATA-2 | chr3 | GO:0035295 | Census, Compendium | Yes | 72 | 0.15 | 370 | 49 | 0.132 | 6 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0035295 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GDF11 | GDF11 | O95390 | Growth/differentiation factor 11 | chr12 | GO:0035295 | Not Cancer Driver | No | 40 | 0.098 | 109 | 7 | 0.064 | 1 |
| GJB1_ENST00000647424 | GJB1 | P08034 | Gap junction beta-1 protein | chrX | GO:0035295 | Not Cancer Driver | No | 34 | 0.12 | 23 | 7 | 0.304 | 189 |
| GJB2_ENST00000382848 | GJB2 | P29033 | Gap junction beta-2 protein | chr13 | GO:0035295 | Not Cancer Driver | No | 34 | 0.15 | 0 | 0 | 0.0 | 46 |
| GJB5 | GJB5 | O95377 | Gap junction beta-5 protein | chr1 | GO:0035295 | Not Cancer Driver | No | 38 | 0.139 | 8 | 5 | 0.625 | 0 |
| GLI2_ENST00000361492 | GLI2 | P10070 | Zinc finger protein GLI2 | chr2 | GO:0035295 | Not Cancer Driver | No | 287 | 0.181 | 1403 | 244 | 0.174 | 2 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0035295 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
| GREB1L | GREB1L | Q9C091 | GREB1-like protein | chr18 | GO:0035295 | Not Cancer Driver | No | 87 | 0.045 | 480 | 22 | 0.046 | 25 |
| HECA | HECA | Q9UBI9 | Headcase protein homolog | chr6 | GO:0035295 | Not Cancer Driver | No | 76 | 0.14 | 177 | 24 | 0.136 | 0 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0035295 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HEYL | HEYL | Q9NQ87 | Hairy/enhancer-of-split related with YRPW motif-like protein | chr1 | GO:0035295 | Not Cancer Driver | No | 44 | 0.134 | 198 | 19 | 0.096 | 0 |
| HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0035295 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
| HOXA5 | HOXA5 | P20719 | Homeobox protein Hox-A5 | chr7 | GO:0035295 | Not Cancer Driver | No | 43 | 0.159 | 209 | 37 | 0.177 | 0 |
| IFT172 | IFT172 | Q9UG01 | Intraflagellar transport protein 172 homolog | chr2 | GO:0035295 | Not Cancer Driver | No | 219 | 0.125 | 96 | 10 | 0.104 | 8 |
| ING2 | ING2 | Q9H160 | Inhibitor of growth protein 2 | chr4 | GO:0035295 | Not Cancer Driver | No | 33 | 0.118 | 169 | 26 | 0.154 | 0 |
| INHBB | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0035295 | Not Cancer Driver | No | 61 | 0.15 | 98 | 5 | 0.051 | 0 |
| ITGB3 | ITGB3 | P05106 | Integrin beta-3 | chr17 | GO:0035295 | Not Cancer Driver | No | 124 | 0.157 | 66 | 5 | 0.076 | 30 |
| ITGB6_ENST00000409872 | ITGB6 | P18564 | Integrin beta-6 | chr2 | GO:0035295 | Not Cancer Driver | No | 120 | 0.152 | 26 | 4 | 0.154 | 3 |
| JAG1 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0035295 | Not Cancer Driver | No | 182 | 0.149 | 172 | 20 | 0.116 | 52 |
| KIF18A | KIF18A | Q8NI77 | Kinesin-like protein KIF18A | chr11 | GO:0035295 | Not Cancer Driver | No | 114 | 0.127 | 405 | 60 | 0.148 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0035295 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:0035295 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| MIXL1_ENST00000366810 | MIXL1 | Q9H2W2 | Homeobox protein MIXL1 | chr1 | GO:0035295 | Not Cancer Driver | No | 18 | 0.078 | 157 | 10 | 0.064 | 0 |
| MKS1 | MKS1 | Q9NXB0 | Meckel syndrome type 1 protein | chr17 | GO:0035295 | Not Cancer Driver | No | 82 | 0.147 | 152 | 23 | 0.151 | 2 |
| MMP12 | MMP12 | P39900 | Macrophage metalloelastase | chr11 | GO:0035295 | Not Cancer Driver | No | 100 | 0.213 | 29 | 5 | 0.172 | 0 |
| MYOCD_ENST00000343344 | MYOCD | Q8IZQ8 | Myocardin | chr17 | GO:0035295 | Not Cancer Driver | No | 284 | 0.303 | 853 | 263 | 0.308 | 0 |
| NIPBL | NIPBL | Q6KC79 | Nipped-B-like protein | chr5 | GO:0035295 | Compendium | Yes | 353 | 0.126 | 1528 | 184 | 0.12 | 37 |
| NKX2-2 | NKX2-2 | O95096 | Homeobox protein Nkx-2.2 | chr20 | GO:0035295 | Not Cancer Driver | No | 84 | 0.308 | 206 | 65 | 0.316 | 0 |
| NKX2-6 | NKX2-6 | A6NCS4 | Homeobox protein Nkx-2.6 | chr8 | GO:0035295 | Not Cancer Driver | No | 10 | 0.033 | 243 | 7 | 0.029 | 3 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0035295 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2 | NOTCH2 | Q04721 | Neurogenic locus notch homolog protein 2 | chr1 | GO:0035295 | Census, Compendium | Yes | 282 | 0.114 | 630 | 77 | 0.122 | 1 |
| NPNT_ENST00000379987 | NPNT | Q6UXI9 | Nephronectin | chr4 | GO:0035295 | Not Cancer Driver | No | 90 | 0.159 | 218 | 33 | 0.151 | 0 |
| OSR1 | OSR1 | Q8TAX0 | Protein odd-skipped-related 1 | chr2 | GO:0035295 | Not Cancer Driver | No | 57 | 0.214 | 67 | 17 | 0.254 | 0 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0035295 | Not Cancer Driver | No | 89 | 0.251 | 24 | 4 | 0.167 | 111 |
| OXTR | OXTR | P30559 | Oxytocin receptor | chr3 | GO:0035295 | Not Cancer Driver | No | 46 | 0.118 | 18 | 0 | 0.0 | 0 |
| PAX2_ENST00000428433 | PAX2 | Q02962 | Paired box protein Pax-2 | chr10 | GO:0035295 | Not Cancer Driver | No | 62 | 0.149 | 296 | 48 | 0.162 | 23 |
| PAX8 | PAX8 | Q06710 | Paired box protein Pax-8 | chr2 | GO:0035295 | Census | Yes | 84 | 0.187 | 291 | 55 | 0.189 | 4 |
| PCSK5 | PCSK5 | Q92824 | Proprotein convertase subtilisin/kexin type 5 | chr9 | GO:0035295 | Not Cancer Driver | No | 319 | 0.172 | 168 | 25 | 0.149 | 0 |
| PDGFC | PDGFC | Q9NRA1 | Platelet-derived growth factor C | chr4 | GO:0035295 | Not Cancer Driver | No | 86 | 0.249 | 53 | 12 | 0.226 | 0 |
| PDX1 | PDX1 | P52945 | Pancreas/duodenum homeobox protein 1 | chr13 | GO:0035295 | Not Cancer Driver | No | 32 | 0.113 | 238 | 23 | 0.097 | 0 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0035295 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0035295 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PKDCC | PKDCC | Q504Y2 | Extracellular tyrosine-protein kinase PKDCC | chr2 | GO:0035295 | Not Cancer Driver | No | 36 | 0.073 | 124 | 0 | 0.0 | 0 |
| POU3F3 | POU3F3 | P20264 | POU domain, class 3, transcription factor 3 | chr2 | GO:0035295 | Not Cancer Driver | No | 43 | 0.086 | 402 | 30 | 0.075 | 4 |
| PTCH1 | PTCH1 | Q13635 | Protein patched homolog 1 | chr9 | GO:0035295 | Census, Compendium | Yes | 243 | 0.168 | 382 | 67 | 0.175 | 18 |
| PTPN6_ENST00000318974 | PTPN6 | P29350 | Tyrosine-protein phosphatase non-receptor type 6 | chr12 | GO:0035295 | Census, Compendium | Yes | 73 | 0.123 | 192 | 25 | 0.13 | 0 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0035295 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RARRES2 | RARRES2 | Q99969 | Retinoic acid receptor responder protein 2 | chr7 | GO:0035295 | Not Cancer Driver | No | 16 | 0.098 | 14 | 2 | 0.143 | 0 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0035295 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| REC8_ENST00000611366 | REC8 | O95072 | Meiotic recombination protein REC8 homolog | chr14 | GO:0035295 | Not Cancer Driver | No | 60 | 0.11 | 244 | 26 | 0.107 | 0 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0035295 | Census, Compendium | Yes | 208 | 0.187 | 105 | 12 | 0.114 | 139 |
| ROBO2_ENST00000461745 | ROBO2 | Q9HCK4 | Roundabout homolog 2 | chr3 | GO:0035295 | Census | Yes | 407 | 0.295 | 874 | 259 | 0.296 | 2 |
| SALL1 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | GO:0035295 | Not Cancer Driver | No | 454 | 0.343 | 949 | 334 | 0.352 | 0 |
| SCT | SCT | P09683 | Secretin | chr11 | GO:0035295 | Not Cancer Driver | No | 4 | 0.033 | 71 | 3 | 0.042 | 0 |
| SDC1_ENST00000254351 | SDC1 | P18827 | Syndecan-1 | chr2 | GO:0035295 | Not Cancer Driver | No | 31 | 0.1 | 259 | 30 | 0.116 | 0 |
| SDC4 | SDC4 | P31431 | Syndecan-4 | chr20 | GO:0035295 | Census, Compendium | Yes | 34 | 0.172 | 110 | 25 | 0.227 | 0 |
| SERPINE2_ENST00000258405 | SERPINE2 | P07093 | Glia-derived nexin | chr2 | GO:0035295 | Not Cancer Driver | No | 62 | 0.156 | 0 | 0 | 0.0 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0035295 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SHH | SHH | Q15465 | Sonic hedgehog protein | chr7 | GO:0035295 | Not Cancer Driver | No | 56 | 0.121 | 139 | 14 | 0.101 | 81 |
| SIM1_ENST00000262901 | SIM1 | P81133 | Single-minded homolog 1 | chr6 | GO:0035295 | Not Cancer Driver | No | 223 | 0.291 | 376 | 120 | 0.319 | 0 |
| SIX1_ENST00000645694 | SIX1 | Q15475 | Homeobox protein SIX1 | chr14 | GO:0035295 | Census, Compendium | Yes | 49 | 0.173 | 144 | 25 | 0.174 | 8 |
| SLC4A2 | SLC4A2 | P04920 | Anion exchange protein 2 | chr7 | GO:0035295 | Not Cancer Driver | No | 150 | 0.121 | 509 | 62 | 0.122 | 0 |
| SLIT2 | SLIT2 | O94813 | Slit homolog 2 protein | chr4 | GO:0035295 | Not Cancer Driver | No | 428 | 0.28 | 31 | 13 | 0.419 | 0 |
| SMAD1 | SMAD1 | Q15797 | Mothers against decapentaplegic homolog 1 | chr4 | GO:0035295 | Not Cancer Driver | No | 54 | 0.116 | 161 | 22 | 0.137 | 0 |
| SMAD2_ENST00000402690 | SMAD2 | Q15796 | Mothers against decapentaplegic homolog 2 | chr18 | GO:0035295 | Census, Compendium | Yes | 79 | 0.169 | 137 | 12 | 0.088 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0035295 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SMAD4_ENST00000398417 | SMAD4 | Q13485 | Mothers against decapentaplegic homolog 4 | chr18 | GO:0035295 | Census, Compendium | Yes | 198 | 0.359 | 195 | 17 | 0.087 | 8 |
| SMAD5_ENST00000509297 | SMAD5 | Q99717 | Mothers against decapentaplegic homolog 5 | chr5 | GO:0035295 | Not Cancer Driver | No | 44 | 0.095 | 172 | 11 | 0.064 | 0 |
| SMAD6 | SMAD6 | O43541 | Mothers against decapentaplegic homolog 6 | chr15 | GO:0035295 | Not Cancer Driver | No | 38 | 0.077 | 248 | 7 | 0.028 | 7 |
| SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0035295 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
| SMO | SMO | Q99835 | Smoothened homolog | chr7 | GO:0035295 | Census, Compendium | Yes | 112 | 0.142 | 241 | 27 | 0.112 | 1 |
| SOX17 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0035295 | Compendium | Yes | 81 | 0.196 | 378 | 59 | 0.156 | 2 |
| SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0035295 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
| SPATA2_ENST00000289431 | SPATA2 | Q9UM82 | Spermatogenesis-associated protein 2 | chr20 | GO:0035295 | Not Cancer Driver | No | 70 | 0.135 | 235 | 39 | 0.166 | 0 |
| SPRY1 | SPRY1 | O43609 | Protein sprouty homolog 1 | chr4 | GO:0035295 | Not Cancer Driver | No | 46 | 0.144 | 168 | 26 | 0.155 | 0 |
| STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0035295 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
| STRA6_ENST00000323940 | STRA6 | Q9BX79 | Receptor for retinol uptake STRA6 | chr15 | GO:0035295 | Not Cancer Driver | No | 77 | 0.115 | 84 | 14 | 0.167 | 6 |
| TBC1D20 | TBC1D20 | Q96BZ9 | TBC1 domain family member 20 | chr20 | GO:0035295 | Not Cancer Driver | No | 52 | 0.129 | 99 | 10 | 0.101 | 0 |
| TCF21 | TCF21 | O43680 | Transcription factor 21 | chr6 | GO:0035295 | Not Cancer Driver | No | 55 | 0.307 | 120 | 40 | 0.333 | 0 |
| TFAP2B | TFAP2B | Q92481 | Transcription factor AP-2-beta | chr6 | GO:0035295 | Not Cancer Driver | No | 114 | 0.248 | 306 | 75 | 0.245 | 6 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0035295 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TGFB3 | TGFB3 | P10600 | Transforming growth factor beta-3 proprotein | chr14 | GO:0035295 | Not Cancer Driver | No | 45 | 0.109 | 96 | 14 | 0.146 | 1 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0035295 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0035295 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TRAF4 | TRAF4 | Q9BUZ4 | TNF receptor-associated factor 4 | chr17 | GO:0035295 | Not Cancer Driver | No | 42 | 0.089 | 27 | 1 | 0.037 | 0 |
| TTC8_ENST00000338104 | TTC8 | Q8TAM2 | Tetratricopeptide repeat protein 8 | chr14 | GO:0035295 | Not Cancer Driver | No | 74 | 0.137 | 98 | 12 | 0.122 | 0 |
| UBB_ENST00000614404 | UBB | P0CG47 | Polyubiquitin-B | chr17 | GO:0035295 | Not Cancer Driver | No | 20 | 0.087 | 102 | 8 | 0.078 | 0 |
| VPS52 | VPS52 | Q8N1B4 | Vacuolar protein sorting-associated protein 52 homolog | chr6 | GO:0035295 | Not Cancer Driver | No | 89 | 0.123 | 36 | 5 | 0.139 | 0 |
| WDR48 | WDR48 | Q8TAF3 | WD repeat-containing protein 48 | chr3 | GO:0035295 | Not Cancer Driver | No | 61 | 0.09 | 125 | 19 | 0.152 | 0 |
| WNT11 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0035295 | Not Cancer Driver | No | 55 | 0.155 | 59 | 4 | 0.068 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0035295 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0035295 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0035295 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| WNT7B | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0035295 | Not Cancer Driver | No | 55 | 0.158 | 11 | 1 | 0.091 | 0 |
| WNT9B | WNT9B | O14905 | Protein Wnt-9b | chr17 | GO:0035295 | Not Cancer Driver | No | 47 | 0.132 | 11 | 4 | 0.364 | 0 |