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Total number of protein in "GO:0032970" GO term:  248

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0032970 Not Cancer Driver No 56 0.109 361 38 0.105 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0032970 Not Cancer Driver No 46 0.126 248 31 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0032970 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0032970 Census, Compendium Yes 171 0.145 641 70 0.109 0
ABRACL ABRACL Q9P1F3 Costars family protein ABRACL chr6 GO:0032970 Not Cancer Driver No 6 0.074 0 0 0.0 0
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 GO:0032970 Not Cancer Driver No 50 0.133 39 4 0.103 17
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0032970 Not Cancer Driver No 227 0.254 131 29 0.221 9
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0032970 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADD2_ENST00000407644 ADD2 P35612 Beta-adducin chr2 GO:0032970 Not Cancer Driver No 157 0.216 423 104 0.246 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 GO:0032970 Not Cancer Driver No 95 0.135 381 48 0.126 1
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0032970 Not Cancer Driver No 64 0.196 12 4 0.333 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0032970 Not Cancer Driver No 359 0.128 2091 258 0.123 0
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0032970 Not Cancer Driver No 770 0.195 2844 566 0.199 4
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 GO:0032970 Not Cancer Driver No 24 0.079 257 24 0.093 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0032970 Not Cancer Driver No 28 0.105 131 8 0.061 3
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 GO:0032970 Not Cancer Driver No 152 0.105 401 28 0.07 0
ARF1_ENST00000272102 ARF1 P84077 ADP-ribosylation factor 1 chr1 GO:0032970 Not Cancer Driver No 30 0.166 4 2 0.5 2
ARFIP1 ARFIP1 P53367 Arfaptin-1 chr4 GO:0032970 Not Cancer Driver No 43 0.115 145 19 0.131 0
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 GO:0032970 Not Cancer Driver No 37 0.109 144 15 0.104 0
ARHGAP28_ENST00000383472 ARHGAP28 Q9P2N2 Rho GTPase-activating protein 28 chr18 GO:0032970 Not Cancer Driver No 121 0.166 336 45 0.134 0
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0032970 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0032970 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0032970 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0032970 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0032970 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0032970 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0032970 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARPIN ARPIN Q7Z6K5 Arpin chr15 GO:0032970 Not Cancer Driver No 26 0.115 110 14 0.127 0
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0032970 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP2A1 ATP2A1 O14983 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 chr16 GO:0032970 Not Cancer Driver No 157 0.157 80 11 0.138 1
AVIL AVIL O75366 Advillin chr12 GO:0032970 Not Cancer Driver No 91 0.111 138 17 0.123 2
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0032970 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0032970 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 GO:0032970 Not Cancer Driver No 76 0.149 293 42 0.143 0
BAIAP2L2 BAIAP2L2 Q6UXY1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 chr22 GO:0032970 Not Cancer Driver No 41 0.078 338 24 0.071 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0032970 Not Cancer Driver No 134 0.144 417 67 0.161 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0032970 Not Cancer Driver No 65 0.11 456 42 0.092 5
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0032970 Not Cancer Driver No 88 0.208 87 13 0.149 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 GO:0032970 Not Cancer Driver No 7 0.093 14 1 0.071 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0032970 Not Cancer Driver No 455 0.205 744 146 0.196 14
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0032970 Not Cancer Driver No 45 0.129 95 7 0.074 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 GO:0032970 Not Cancer Driver No 40 0.14 41 2 0.049 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 GO:0032970 Not Cancer Driver No 37 0.129 19 0 0.0 0
CAPZA3 CAPZA3 Q96KX2 F-actin-capping protein subunit alpha-3 chr12 GO:0032970 Not Cancer Driver No 87 0.291 0 0 0.0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 GO:0032970 Not Cancer Driver No 33 0.119 66 3 0.045 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0032970 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0032970 Not Cancer Driver No 154 0.107 669 75 0.112 4
CARMIL3 CARMIL3 Q8ND23 Capping protein, Arp2/3 and myosin-I linker protein 3 chr14 GO:0032970 Not Cancer Driver No 186 0.136 583 76 0.13 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0032970 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0032970 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0032970 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0032970 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0032970 Not Cancer Driver No 58 0.166 0 0 0.0 0
CD2AP CD2AP Q9Y5K6 CD2-associated protein chr6 GO:0032970 Not Cancer Driver No 80 0.125 456 60 0.132 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0032970 Not Cancer Driver No 37 0.115 0 0 0.0 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0032970 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0032970 Not Cancer Driver No 48 0.164 5 1 0.2 0
CFL2_ENST00000341223 CFL2 Q9Y281 Cofilin-2 chr14 GO:0032970 Not Cancer Driver No 25 0.151 0 0 0.0 1
CGNL1 CGNL1 Q0VF96 Cingulin-like protein 1 chr15 GO:0032970 Not Cancer Driver No 191 0.147 1223 182 0.149 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0032970 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0032970 Not Cancer Driver No 158 0.122 676 94 0.139 0
CNN2_ENST00000263097 CNN2 Q99439 Calponin-2 chr19 GO:0032970 Not Cancer Driver No 35 0.113 166 23 0.139 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0032970 Not Cancer Driver No 51 0.111 126 15 0.119 1
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0032970 Not Cancer Driver No 41 0.084 138 10 0.072 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0032970 Not Cancer Driver No 85 0.177 37 7 0.189 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0032970 Census Yes 133 0.137 124 17 0.137 20
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0032970 Not Cancer Driver No 20 0.097 7 0 0.0 0
CTNNA2 CTNNA2 P26232 Catenin alpha-2 chr2 GO:0032970 Census Yes 387 0.406 307 130 0.423 0
CTNNA3 CTNNA3 Q9UI47 Catenin alpha-3 chr10 GO:0032970 Not Cancer Driver No 269 0.301 186 50 0.269 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0032970 Not Cancer Driver No 66 0.166 259 44 0.17 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0032970 Not Cancer Driver No 46 0.037 96 0 0.0 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0032970 Not Cancer Driver No 56 0.123 82 7 0.085 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0032970 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0032970 Not Cancer Driver No 120 0.133 460 67 0.146 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0032970 Not Cancer Driver No 53 0.131 348 46 0.132 0
DSC2 DSC2 Q02487 Desmocollin-2 chr18 GO:0032970 Not Cancer Driver No 192 0.213 257 61 0.237 5
DSG2 DSG2 Q14126 Desmoglein-2 chr18 GO:0032970 Not Cancer Driver No 173 0.155 476 68 0.143 5
DSP DSP P15924 Desmoplakin chr6 GO:0032970 Not Cancer Driver No 483 0.168 1124 204 0.181 6
DSTN DSTN P60981 Destrin chr20 GO:0032970 Not Cancer Driver No 18 0.109 0 0 0.0 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0032970 Not Cancer Driver No 104 0.114 284 33 0.116 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0032970 Not Cancer Driver No 37 0.175 97 20 0.206 3
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0032970 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0032970 Not Cancer Driver No 106 0.129 459 54 0.118 0
ESAM ESAM Q96AP7 Endothelial cell-selective adhesion molecule chr11 GO:0032970 Not Cancer Driver No 54 0.138 154 30 0.195 0
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 GO:0032970 Not Cancer Driver No 42 0.101 335 37 0.11 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0032970 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0032970 Not Cancer Driver No 55 0.139 7 2 0.286 0
FCHSD2 FCHSD2 O94868 F-BAR and double SH3 domains protein 2 chr11 GO:0032970 Not Cancer Driver No 61 0.082 391 30 0.077 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0032970 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0032970 Census Yes 103 0.125 245 34 0.139 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0032970 Not Cancer Driver No 151 0.13 575 82 0.143 0
FLII FLII Q13045 Protein flightless-1 homolog chr17 GO:0032970 Not Cancer Driver No 128 0.101 206 32 0.155 0
FLNA FLNA P21333 Filamin-A chrX GO:0032970 Census Yes 416 0.157 1456 214 0.147 28
FMN1 FMN1 Q68DA7 Formin-1 chr15 GO:0032970 Not Cancer Driver No 117 0.082 983 67 0.068 0
FRMD6 FRMD6 Q96NE9 FERM domain-containing protein 6 chr14 GO:0032970 Not Cancer Driver No 116 0.186 195 36 0.185 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0032970 Not Cancer Driver No 147 0.206 256 59 0.23 25
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0032970 Not Cancer Driver No 48 0.109 301 34 0.113 18
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0032970 Not Cancer Driver No 74 0.207 92 21 0.228 5
GMFB GMFB P60983 Glia maturation factor beta chr14 GO:0032970 Not Cancer Driver No 18 0.127 11 0 0.0 0
GMFG GMFG O60234 Glia maturation factor gamma chr19 GO:0032970 Not Cancer Driver No 22 0.155 10 0 0.0 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0032970 Not Cancer Driver No 70 0.208 0 0 0.0 0
GSN GSN P06396 Gelsolin chr9 GO:0032970 Not Cancer Driver No 76 0.097 316 28 0.089 2
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0032970 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0032970 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0032970 Not Cancer Driver No 103 0.212 446 94 0.211 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0032970 Not Cancer Driver No 94 0.088 524 34 0.065 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0032970 Census, Compendium Yes 107 0.566 16 4 0.25 18
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0032970 Not Cancer Driver No 20 0.129 17 6 0.353 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0032970 Not Cancer Driver No 42 0.094 34 2 0.059 7
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 GO:0032970 Not Cancer Driver No 237 0.15 255 50 0.196 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0032970 Not Cancer Driver No 26 0.13 58 11 0.19 0
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0032970 Not Cancer Driver No 50 0.161 62 11 0.177 2
JUP JUP P14923 Junction plakoglobin chr17 GO:0032970 Not Cancer Driver No 112 0.15 241 37 0.154 0
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0032970 Not Cancer Driver No 103 0.241 49 11 0.224 12
KIAA1211 CRACD Q6ZU35 Capping protein-inhibiting regulator of actin dynamics chr4 GO:0032970 Not Cancer Driver No 245 0.199 1210 241 0.199 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 GO:0032970 Not Cancer Driver No 88 0.116 687 81 0.118 0
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0032970 Not Cancer Driver No 177 0.163 880 140 0.159 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0032970 Not Cancer Driver No 110 0.17 170 30 0.176 0
LMOD1 LMOD1 P29536 Leiomodin-1 chr1 GO:0032970 Not Cancer Driver No 97 0.162 499 80 0.16 0
LMOD2 LMOD2 Q6P5Q4 Leiomodin-2 chr7 GO:0032970 Not Cancer Driver No 94 0.172 451 79 0.175 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0032970 Not Cancer Driver No 99 0.177 456 84 0.184 1
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0032970 Not Cancer Driver No 79 0.217 21 6 0.286 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 GO:0032970 Not Cancer Driver No 178 0.143 1010 118 0.117 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0032970 Not Cancer Driver No 15 0.105 20 2 0.1 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0032970 Census, Compendium Yes 226 0.163 62 15 0.242 19
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0032970 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTPN MTPN P58546 Myotrophin chr7 GO:0032970 Not Cancer Driver No 11 0.093 11 3 0.273 0
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0032970 Not Cancer Driver No 107 0.142 584 86 0.147 0
MYBPC3 MYBPC3 Q14896 Myosin-binding protein C, cardiac-type chr11 GO:0032970 Not Cancer Driver No 178 0.14 434 62 0.143 64
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0032970 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 GO:0032970 Not Cancer Driver No 118 0.198 277 64 0.231 2
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0032970 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYOC MYOC Q99972 Myocilin chr1 GO:0032970 Not Cancer Driver No 92 0.183 196 43 0.219 58
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0032970 Not Cancer Driver No 129 0.114 44 3 0.068 0
NF2 NF2 P35240 Merlin chr22 GO:0032970 Census, Compendium Yes 69 0.116 252 26 0.103 16
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0032970 Census, Compendium Yes 282 0.114 630 77 0.122 1
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0032970 Compendium Yes 146 0.158 211 31 0.147 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0032970 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0032970 Census, Compendium Yes 249 0.297 57 21 0.368 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0032970 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0032970 Compendium Yes 89 0.17 242 49 0.202 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0032970 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0032970 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0032970 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0032970 Not Cancer Driver No 37 0.228 96 24 0.25 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0032970 Not Cancer Driver No 14 0.047 38 4 0.105 0
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0032970 Not Cancer Driver No 16 0.114 7 1 0.143 3
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0032970 Not Cancer Driver No 20 0.143 0 0 0.0 0
PFN3 PFN3 P60673 Profilin-3 chr5 GO:0032970 Not Cancer Driver No 8 0.058 0 0 0.0 0
PFN4 PFN4 Q8NHR9 Profilin-4 chr2 GO:0032970 Not Cancer Driver No 17 0.132 0 0 0.0 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0032970 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PHPT1 PHPT1 Q9NRX4 14 kDa phosphohistidine phosphatase chr9 GO:0032970 Not Cancer Driver No 13 0.104 6 0 0.0 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0032970 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0032970 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0032970 Census, Compendium Yes 154 0.213 268 61 0.228 2
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0032970 Not Cancer Driver No 176 0.2 434 98 0.226 8
PLEK PLEK P08567 Pleckstrin chr2 GO:0032970 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHH2 PLEKHH2 Q8IVE3 Pleckstrin homology domain-containing family H member 2 chr2 GO:0032970 Not Cancer Driver No 219 0.147 653 101 0.155 0
PLN PLN P26678 Cardiac phospholamban chr6 GO:0032970 Not Cancer Driver No 10 0.192 0 0 0.0 3
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 GO:0032970 Not Cancer Driver No 164 0.136 865 126 0.146 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 GO:0032970 Not Cancer Driver No 114 0.151 384 53 0.138 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0032970 Not Cancer Driver No 53 0.117 242 24 0.099 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0032970 Not Cancer Driver No 110 0.237 78 15 0.192 31
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0032970 Not Cancer Driver No 182 0.247 537 141 0.263 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0032970 Not Cancer Driver No 161 0.16 261 37 0.142 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0032970 Not Cancer Driver No 62 0.105 341 24 0.07 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0032970 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0032970 Not Cancer Driver No 97 0.105 197 19 0.096 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0032970 Not Cancer Driver No 71 0.122 297 37 0.125 1
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0032970 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0032970 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0032970 Not Cancer Driver No 30 0.155 53 7 0.132 0
RHPN1 RHPN1 Q8TCX5 Rhophilin-1 chr8 GO:0032970 Not Cancer Driver No 70 0.104 257 27 0.105 0
RHPN2 RHPN2 Q8IUC4 Rhophilin-2 chr19 GO:0032970 Compendium Yes 111 0.162 88 17 0.193 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0032970 Not Cancer Driver No 145 0.104 732 81 0.111 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0032970 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0032970 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0032970 Not Cancer Driver No 86 0.225 29 6 0.207 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0032970 Not Cancer Driver No 100 0.14 170 35 0.206 0
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0032970 Not Cancer Driver No 491 0.244 550 144 0.262 190
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0032970 Census, Compendium Yes 34 0.172 110 25 0.227 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0032970 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0032970 Not Cancer Driver No 266 0.248 23 4 0.174 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0032970 Not Cancer Driver No 62 0.126 112 21 0.188 1
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0032970 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3BP1 SH3BP1 Q9Y3L3 SH3 domain-binding protein 1 chr22 GO:0032970 Not Cancer Driver No 57 0.081 430 31 0.072 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0032970 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0032970 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0032970 Census, Compendium Yes 198 0.359 195 17 0.087 8
SORBS3 SORBS3 O60504 Vinexin chr8 GO:0032970 Not Cancer Driver No 62 0.092 577 56 0.097 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0032970 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 GO:0032970 Not Cancer Driver No 315 0.127 980 114 0.116 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0032970 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0032970 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0032970 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPTBN5 SPTBN5 Q9NRC6 Spectrin beta chain, non-erythrocytic 5 chr15 GO:0032970 Not Cancer Driver No 314 0.085 1274 118 0.093 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0032970 Not Cancer Driver No 328 0.153 562 70 0.125 7
SRI SRI P30626 Sorcin chr7 GO:0032970 Not Cancer Driver No 15 0.076 32 2 0.062 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0032970 Not Cancer Driver No 66 0.224 103 18 0.175 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0032970 Not Cancer Driver No 59 0.239 58 12 0.207 0
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0032970 Not Cancer Driver No 15 0.101 149 15 0.101 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0032970 Not Cancer Driver No 10 0.099 76 7 0.092 0
SVIL SVIL O95425 Supervillin chr10 GO:0032970 Not Cancer Driver No 308 0.139 1423 192 0.135 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0032970 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 GO:0032970 Not Cancer Driver No 103 0.111 918 102 0.111 0
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0032970 Not Cancer Driver No 103 0.105 950 99 0.104 0
SYNPO2_ENST00000429713 SYNPO2 Q9UMS6 Synaptopodin-2 chr4 GO:0032970 Not Cancer Driver No 240 0.22 978 219 0.224 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0032970 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0032970 Not Cancer Driver No 22 0.068 27 1 0.037 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0032970 Not Cancer Driver No 219 0.195 126 22 0.175 10
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0032970 Not Cancer Driver No 63 0.101 339 35 0.103 0
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0032970 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0032970 Not Cancer Driver No 86 0.171 23 3 0.13 15
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0032970 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TMEFF2 TMEFF2 Q9UIK5 Tomoregulin-2 chr2 GO:0032970 Not Cancer Driver No 81 0.217 68 8 0.118 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 GO:0032970 Not Cancer Driver No 41 0.114 195 29 0.149 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0032970 Not Cancer Driver No 33 0.094 216 22 0.102 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 GO:0032970 Not Cancer Driver No 40 0.114 190 24 0.126 0
TMOD4 TMOD4 Q9NZQ9 Tropomodulin-4 chr1 GO:0032970 Not Cancer Driver No 37 0.107 218 22 0.101 0
TMSB10 TMSB10 P63313 Thymosin beta-10 chr2 GO:0032970 Not Cancer Driver No 2 0.045 44 2 0.045 0
TMSB15A TMSB15A P0CG34 Thymosin beta-15A chrX GO:0032970 Not Cancer Driver No 8 0.178 45 8 0.178 0
TMSB15B TMSB15B P0CG35 Thymosin beta-15B chrX GO:0032970 Not Cancer Driver No 7 0.156 45 7 0.156 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0032970 Census Yes 7 0.159 44 7 0.159 0
TMSB4Y TMSB4Y O14604 Thymosin beta-4, Y-chromosomal chrY GO:0032970 Not Cancer Driver No 1 0.023 44 1 0.023 0
TNNC1 TNNC1 P63316 Troponin C, slow skeletal and cardiac muscles chr3 GO:0032970 Not Cancer Driver No 19 0.118 67 6 0.09 6
TNNT2 TNNT2 P45379 Troponin T, cardiac muscle chr1 GO:0032970 Not Cancer Driver No 59 0.198 272 53 0.195 21
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0032970 Not Cancer Driver No 33 0.116 234 29 0.124 8
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0032970 Census Yes 59 0.115 87 11 0.126 0
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0032970 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0032970 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0032970 Not Cancer Driver No 152 0.125 149 18 0.121 12
TSC1 TSC1 Q92574 Hamartin chr9 GO:0032970 Census, Compendium Yes 135 0.116 732 78 0.107 11
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0032970 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0032970 Not Cancer Driver No 34 0.097 59 8 0.136 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0032970 Not Cancer Driver No 124 0.15 222 38 0.171 0
VILL_ENST00000383759 VILL O15195 Villin-like protein chr3 GO:0032970 Not Cancer Driver No 100 0.117 222 28 0.126 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0032970 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0032970 Not Cancer Driver No 63 0.113 445 49 0.11 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0032970 Not Cancer Driver No 61 0.122 400 43 0.107 0
WASF3 WASF3 Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 chr13 GO:0032970 Not Cancer Driver No 108 0.215 386 84 0.218 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 GO:0032970 Not Cancer Driver No 90 0.068 1204 89 0.074 0
WASHC5 WASHC5 Q12768 WASH complex subunit 5 chr8 GO:0032970 Not Cancer Driver No 152 0.131 23 6 0.261 6
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0032970 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0032970 Not Cancer Driver No 66 0.109 30 7 0.233 2
WDR63 DNAI3 Q8IWG1 Dynein axonemal intermediate chain 3 chr1 GO:0032970 Not Cancer Driver No 129 0.145 210 31 0.148 0
WHAMM WHAMM Q8TF30 WASP homolog-associated protein with actin, membranes and microtubules chr15 GO:0032970 Not Cancer Driver No 59 0.073 399 38 0.095 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0032970 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0032970 Not Cancer Driver No 30 0.085 39 4 0.103 4