Total number of protein in "GO:0032869" GO term: 99
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0032869 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0032869 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0032869 | Census | Yes | 77 | 0.16 | 84 | 9 | 0.107 | 2 |
| APRT | APRT | P07741 | Adenine phosphoribosyltransferase | chr16 | GO:0032869 | Not Cancer Driver | No | 16 | 0.089 | 0 | 0 | 0.0 | 8 |
| C2CD5_ENST00000333957 | C2CD5 | Q86YS7 | C2 domain-containing protein 5 | chr12 | GO:0032869 | Not Cancer Driver | No | 136 | 0.136 | 250 | 40 | 0.16 | 0 |
| CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0032869 | Not Cancer Driver | No | 87 | 0.129 | 52 | 6 | 0.115 | 0 |
| CDK4 | CDK4 | P11802 | Cyclin-dependent kinase 4 | chr12 | GO:0032869 | Census, Compendium | Yes | 52 | 0.172 | 52 | 5 | 0.096 | 3 |
| CEACAM1 | CEACAM1 | P13688 | Carcinoembryonic antigen-related cell adhesion molecule 1 | chr19 | GO:0032869 | Not Cancer Driver | No | 64 | 0.122 | 241 | 25 | 0.104 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0032869 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| CPEB1_ENST00000611031 | CPEB1 | Q9BZB8 | Cytoplasmic polyadenylation element-binding protein 1 | chr15 | GO:0032869 | Not Cancer Driver | No | 90 | 0.159 | 226 | 37 | 0.164 | 0 |
| CPEB2_ENST00000507071 | CPEB2 | Q7Z5Q1 | Cytoplasmic polyadenylation element-binding protein 2 | chr4 | GO:0032869 | Not Cancer Driver | No | 66 | 0.112 | 269 | 17 | 0.063 | 0 |
| CYFIP1_ENST00000610365 | CYFIP1 | Q7L576 | Cytoplasmic FMR1-interacting protein 1 | chr15 | GO:0032869 | Not Cancer Driver | No | 46 | 0.037 | 96 | 0 | 0.0 | 0 |
| DENND4C_ENST00000602925 | DENND4C | Q5VZ89 | DENN domain-containing protein 4C | chr9 | GO:0032869 | Not Cancer Driver | No | 190 | 0.1 | 710 | 69 | 0.097 | 0 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0032869 | Not Cancer Driver | No | 104 | 0.143 | 311 | 39 | 0.125 | 0 |
| ENPP1 | ENPP1 | P22413 | Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 | chr6 | GO:0032869 | Not Cancer Driver | No | 148 | 0.16 | 101 | 5 | 0.05 | 33 |
| EPRS | EPRS1 | P07814 | Bifunctional glutamate/proline--tRNA ligase | chr1 | GO:0032869 | Not Cancer Driver | No | 204 | 0.135 | 372 | 62 | 0.167 | 1 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| FBP1_ENST00000375326 | FBP1 | P09467 | Fructose-1,6-bisphosphatase 1 | chr9 | GO:0032869 | Not Cancer Driver | No | 33 | 0.098 | 19 | 0 | 0.0 | 4 |
| FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0032869 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
| FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0032869 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
| GCK_ENST00000403799 | GCK | P35557 | Hexokinase-4 | chr7 | GO:0032869 | Not Cancer Driver | No | 88 | 0.189 | 73 | 14 | 0.192 | 107 |
| GCLC | GCLC | P48506 | Glutamate--cysteine ligase catalytic subunit | chr6 | GO:0032869 | Not Cancer Driver | No | 73 | 0.115 | 167 | 18 | 0.108 | 3 |
| GHRHR | GHRHR | Q02643 | Growth hormone-releasing hormone receptor | chr7 | GO:0032869 | Not Cancer Driver | No | 41 | 0.097 | 3 | 0 | 0.0 | 5 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0032869 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0032869 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0032869 | Not Cancer Driver | No | 56 | 0.136 | 35 | 5 | 0.143 | 0 |
| GPLD1 | GPLD1 | P80108 | Phosphatidylinositol-glycan-specific phospholipase D | chr6 | GO:0032869 | Not Cancer Driver | No | 153 | 0.182 | 36 | 9 | 0.25 | 0 |
| GPT_ENST00000528431 | GPT | P24298 | Alanine aminotransferase 1 | chr8 | GO:0032869 | Not Cancer Driver | No | 52 | 0.105 | 51 | 9 | 0.176 | 0 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0032869 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| HDAC5_ENST00000586802 | HDAC5 | Q9UQL6 | Histone deacetylase 5 | chr17 | GO:0032869 | Not Cancer Driver | No | 118 | 0.105 | 718 | 73 | 0.102 | 0 |
| HDAC9_ENST00000432645 | HDAC9 | Q9UKV0 | Histone deacetylase 9 | chr7 | GO:0032869 | Not Cancer Driver | No | 286 | 0.283 | 631 | 178 | 0.282 | 0 |
| HMGCS2 | HMGCS2 | P54868 | Hydroxymethylglutaryl-CoA synthase, mitochondrial | chr1 | GO:0032869 | Not Cancer Driver | No | 92 | 0.181 | 29 | 4 | 0.138 | 19 |
| INHBB | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0032869 | Not Cancer Driver | No | 61 | 0.15 | 98 | 5 | 0.051 | 0 |
| INPP5K | INPP5K | Q9BT40 | Inositol polyphosphate 5-phosphatase K | chr17 | GO:0032869 | Not Cancer Driver | No | 42 | 0.094 | 34 | 2 | 0.059 | 7 |
| INSIG1 | INSIG1 | O15503 | Insulin-induced gene 1 protein | chr7 | GO:0032869 | Not Cancer Driver | No | 37 | 0.134 | 43 | 1 | 0.023 | 0 |
| INSIG2 | INSIG2 | Q9Y5U4 | Insulin-induced gene 2 protein | chr2 | GO:0032869 | Not Cancer Driver | No | 47 | 0.209 | 11 | 3 | 0.273 | 0 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0032869 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0032869 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| IRS2 | IRS2 | Q9Y4H2 | Insulin receptor substrate 2 | chr13 | GO:0032869 | Not Cancer Driver | No | 69 | 0.052 | 1112 | 57 | 0.051 | 0 |
| KAT2B | KAT2B | Q92831 | Histone acetyltransferase KAT2B | chr3 | GO:0032869 | Not Cancer Driver | No | 107 | 0.129 | 266 | 27 | 0.102 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0032869 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LPIN1_ENST00000256720 | LPIN1 | Q14693 | Phosphatidate phosphatase LPIN1 | chr2 | GO:0032869 | Not Cancer Driver | No | 120 | 0.135 | 447 | 70 | 0.157 | 0 |
| LPIN2 | LPIN2 | Q92539 | Phosphatidate phosphatase LPIN2 | chr18 | GO:0032869 | Not Cancer Driver | No | 113 | 0.126 | 455 | 56 | 0.123 | 1 |
| LPIN3_ENST00000373257 | LPIN3 | Q9BQK8 | Phosphatidate phosphatase LPIN3 | chr20 | GO:0032869 | Not Cancer Driver | No | 91 | 0.107 | 472 | 50 | 0.106 | 0 |
| MARS | MARS1 | P56192 | Methionine--tRNA ligase, cytoplasmic | chr12 | GO:0032869 | Not Cancer Driver | No | 91 | 0.101 | 151 | 16 | 0.106 | 8 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0032869 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| MYO5A | MYO5A | Q9Y4I1 | Unconventional myosin-Va | chr15 | GO:0032869 | Census, Compendium | Yes | 224 | 0.121 | 497 | 58 | 0.117 | 0 |
| OTOP1 | OTOP1 | Q7RTM1 | Proton channel OTOP1 | chr4 | GO:0032869 | Not Cancer Driver | No | 104 | 0.17 | 89 | 11 | 0.124 | 0 |
| PARP1 | PARP1 | P09874 | Poly [ADP-ribose] polymerase 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 119 | 0.117 | 320 | 34 | 0.106 | 0 |
| PCK1 | PCK1 | P35558 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | chr20 | GO:0032869 | Not Cancer Driver | No | 142 | 0.228 | 110 | 28 | 0.255 | 1 |
| PCK2 | PCK2 | Q16822 | Phosphoenolpyruvate carboxykinase [GTP], mitochondrial | chr14 | GO:0032869 | Not Cancer Driver | No | 91 | 0.142 | 139 | 13 | 0.094 | 0 |
| PCSK9 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0032869 | Not Cancer Driver | No | 86 | 0.124 | 148 | 27 | 0.182 | 9 |
| PDE3B | PDE3B | Q13370 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | chr11 | GO:0032869 | Not Cancer Driver | No | 135 | 0.121 | 393 | 37 | 0.094 | 0 |
| PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0032869 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0032869 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0032869 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
| PKLR | PKLR | P30613 | Pyruvate kinase PKLR | chr1 | GO:0032869 | Not Cancer Driver | No | 112 | 0.195 | 26 | 5 | 0.192 | 101 |
| PKM_ENST00000335181 | PKM | P14618 | Pyruvate kinase PKM | chr15 | GO:0032869 | Not Cancer Driver | No | 78 | 0.147 | 58 | 13 | 0.224 | 0 |
| PLA2G1B | PLA2G1B | P04054 | Phospholipase A2 | chr12 | GO:0032869 | Not Cancer Driver | No | 17 | 0.115 | 0 | 0 | 0.0 | 0 |
| PNPLA3 | PNPLA3 | Q9NST1 | 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 | chr22 | GO:0032869 | Not Cancer Driver | No | 54 | 0.112 | 33 | 7 | 0.212 | 0 |
| POU4F2 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0032869 | Not Cancer Driver | No | 130 | 0.318 | 308 | 87 | 0.282 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0032869 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0032869 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
| PRKCZ | PRKCZ | Q05513 | Protein kinase C zeta type | chr1 | GO:0032869 | Not Cancer Driver | No | 70 | 0.118 | 116 | 11 | 0.095 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0032869 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| RAB10 | RAB10 | P61026 | Ras-related protein Rab-10 | chr2 | GO:0032869 | Not Cancer Driver | No | 19 | 0.095 | 28 | 2 | 0.071 | 0 |
| RAB12 | RAB12 | Q6IQ22 | Ras-related protein Rab-12 | chr18 | GO:0032869 | Not Cancer Driver | No | 22 | 0.09 | 72 | 3 | 0.042 | 0 |
| RAB13 | RAB13 | P51153 | Ras-related protein Rab-13 | chr1 | GO:0032869 | Not Cancer Driver | No | 19 | 0.094 | 40 | 0 | 0.0 | 0 |
| RAB15 | RAB15 | P59190 | Ras-related protein Rab-15 | chr14 | GO:0032869 | Not Cancer Driver | No | 18 | 0.085 | 50 | 5 | 0.1 | 0 |
| RAB31 | RAB31 | Q13636 | Ras-related protein Rab-31 | chr18 | GO:0032869 | Not Cancer Driver | No | 27 | 0.139 | 28 | 11 | 0.393 | 0 |
| RAB8A | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0032869 | Not Cancer Driver | No | 37 | 0.179 | 26 | 3 | 0.115 | 0 |
| RAB8B | RAB8B | Q92930 | Ras-related protein Rab-8B | chr15 | GO:0032869 | Not Cancer Driver | No | 22 | 0.106 | 29 | 2 | 0.069 | 0 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0032869 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| RHOQ | RHOQ | P17081 | Rho-related GTP-binding protein RhoQ | chr2 | GO:0032869 | Not Cancer Driver | No | 25 | 0.122 | 0 | 0 | 0.0 | 0 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0032869 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| SELENOS | SELENOS | Q9BQE4 | Selenoprotein S | chr15 | GO:0032869 | Not Cancer Driver | No | 7 | 0.037 | 122 | 6 | 0.049 | 0 |
| SLC22A12 | SLC22A12 | Q96S37 | Solute carrier family 22 member 12 | chr11 | GO:0032869 | Not Cancer Driver | No | 93 | 0.168 | 10 | 3 | 0.3 | 10 |
| SLC25A33 | SLC25A33 | Q9BSK2 | Solute carrier family 25 member 33 | chr1 | GO:0032869 | Not Cancer Driver | No | 23 | 0.072 | 4 | 0 | 0.0 | 0 |
| SLC29A2_ENST00000544554 | SLC29A2 | Q14542 | Equilibrative nucleoside transporter 2 | chr11 | GO:0032869 | Not Cancer Driver | No | 60 | 0.132 | 30 | 6 | 0.2 | 0 |
| SLC2A4 | SLC2A4 | P14672 | Solute carrier family 2, facilitated glucose transporter member 4 | chr17 | GO:0032869 | Not Cancer Driver | No | 71 | 0.139 | 43 | 8 | 0.186 | 1 |
| SLC39A14_ENST00000381237 | SLC39A14 | Q15043 | Metal cation symporter ZIP14 | chr8 | GO:0032869 | Not Cancer Driver | No | 34 | 0.069 | 42 | 3 | 0.071 | 4 |
| SLC9A1 | SLC9A1 | P19634 | Sodium/hydrogen exchanger 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 89 | 0.109 | 251 | 29 | 0.116 | 1 |
| SORBS1_ENST00000361941 | SORBS1 | Q9BX66 | Sorbin and SH3 domain-containing protein 1 | chr10 | GO:0032869 | Not Cancer Driver | No | 161 | 0.125 | 1111 | 133 | 0.12 | 0 |
| SP1 | SP1 | P08047 | Transcription factor Sp1 | chr12 | GO:0032869 | Not Cancer Driver | No | 96 | 0.122 | 599 | 71 | 0.119 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0032869 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0032869 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SRSF5_ENST00000557154 | SRSF5 | Q13243 | Serine/arginine-rich splicing factor 5 | chr14 | GO:0032869 | Not Cancer Driver | No | 50 | 0.184 | 189 | 40 | 0.212 | 0 |
| STAT1 | STAT1 | P42224 | Signal transducer and activator of transcription 1-alpha/beta | chr2 | GO:0032869 | Not Cancer Driver | No | 131 | 0.175 | 144 | 25 | 0.174 | 26 |
| SYAP1 | SYAP1 | Q96A49 | Synapse-associated protein 1 | chrX | GO:0032869 | Not Cancer Driver | No | 31 | 0.088 | 221 | 22 | 0.1 | 0 |
| TBC1D4 | TBC1D4 | O60343 | TBC1 domain family member 4 | chr13 | GO:0032869 | Not Cancer Driver | No | 173 | 0.133 | 590 | 90 | 0.153 | 0 |
| TRARG1 | TRARG1 | Q8IXB3 | Trafficking regulator of GLUT4 1 | chr17 | GO:0032869 | Not Cancer Driver | No | 33 | 0.186 | 83 | 11 | 0.133 | 0 |
| TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0032869 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
| UCP2 | UCP2 | P55851 | Mitochondrial uncoupling protein 2 | chr11 | GO:0032869 | Not Cancer Driver | No | 31 | 0.1 | 11 | 3 | 0.273 | 0 |
| USF1 | USF1 | P22415 | Upstream stimulatory factor 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 52 | 0.168 | 271 | 44 | 0.162 | 0 |
| VAMP2_ENST00000316509 | VAMP2 | P63027 | Vesicle-associated membrane protein 2 | chr17 | GO:0032869 | Not Cancer Driver | No | 7 | 0.06 | 47 | 4 | 0.085 | 3 |
| WDTC1 | WDTC1 | Q8N5D0 | WD and tetratricopeptide repeats protein 1 | chr1 | GO:0032869 | Not Cancer Driver | No | 81 | 0.12 | 154 | 21 | 0.136 | 0 |
| XBP1 | XBP1 | P17861 | X-box-binding protein 1 | chr22 | GO:0032869 | Not Cancer Driver | No | 19 | 0.073 | 169 | 9 | 0.053 | 0 |
| YWHAG | YWHAG | P61981 | 14-3-3 protein gamma | chr7 | GO:0032869 | Not Cancer Driver | No | 26 | 0.105 | 77 | 9 | 0.117 | 2 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0032869 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |