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Total number of protein in "GO:0031325" GO term:  1495

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADAC AADAC P22760 Arylacetamide deacetylase chr3 GO:0031325 Not Cancer Driver No 80 0.201 4 0 0.0 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0031325 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0031325 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0031325 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX GO:0031325 Not Cancer Driver No 117 0.156 79 14 0.177 4
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0031325 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0031325 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0031325 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0031325 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0031325 Census, Compendium Yes 55 0.108 360 39 0.108 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0031325 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0031325 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0031325 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0031325 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0031325 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0031325 Census, Compendium Yes 89 0.124 47 7 0.149 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0031325 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTL6A ACTL6A O96019 Actin-like protein 6A chr3 GO:0031325 Not Cancer Driver No 61 0.142 74 15 0.203 0
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0031325 Not Cancer Driver No 123 0.137 135 13 0.096 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0031325 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0031325 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0031325 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0031325 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0031325 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0031325 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0031325 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0031325 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0031325 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0031325 Compendium Yes 213 0.134 485 47 0.097 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0031325 Not Cancer Driver No 255 0.189 53 11 0.208 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0031325 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0031325 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0031325 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0031325 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0031325 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0031325 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRA2B ADRA2B P18089 Alpha-2B adrenergic receptor chr2 GO:0031325 Not Cancer Driver No 73 0.162 136 20 0.147 0
ADRA2C ADRA2C P18825 Alpha-2C adrenergic receptor chr4 GO:0031325 Not Cancer Driver No 47 0.102 107 0 0.0 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0031325 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0031325 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGAP2 AGAP2 Q99490 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 chr12 GO:0031325 Not Cancer Driver No 133 0.112 754 81 0.107 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0031325 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0031325 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGT AGT P01019 Angiotensinogen chr1 GO:0031325 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0031325 Not Cancer Driver No 95 0.265 0 0 0.0 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0031325 Not Cancer Driver No 98 0.27 0 0 0.0 0
AGXT2 AGXT2 Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial chr5 GO:0031325 Not Cancer Driver No 136 0.265 11 5 0.455 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0031325 Not Cancer Driver No 120 0.1 500 56 0.112 6
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0031325 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 GO:0031325 Not Cancer Driver No 46 0.144 61 8 0.131 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0031325 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 GO:0031325 Not Cancer Driver No 76 0.118 510 61 0.12 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0031325 Census Yes 474 0.121 2281 268 0.117 1
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0031325 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0031325 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0031325 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0031325 Census Yes 77 0.16 84 9 0.107 2
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:0031325 Not Cancer Driver No 90 0.19 0 0 0.0 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0031325 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0031325 Not Cancer Driver No 7 0.046 31 0 0.0 0
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0031325 Not Cancer Driver No 173 0.133 788 103 0.131 0
AMER1 AMER1 Q5JTC6 APC membrane recruitment protein 1 chrX GO:0031325 Census, Compendium Yes 234 0.206 1039 219 0.211 0
ANG ANG P03950 Angiogenin chr14 GO:0031325 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0031325 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0031325 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 GO:0031325 Not Cancer Driver No 17 0.086 26 6 0.231 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0031325 Not Cancer Driver No 127 0.135 521 71 0.136 2
ANKRD31 ANKRD31 Q8N7Z5 Ankyrin repeat domain-containing protein 31 chr5 GO:0031325 Not Cancer Driver No 62 0.033 1144 34 0.03 0
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0031325 Not Cancer Driver No 105 0.186 183 44 0.24 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0031325 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0031325 Not Cancer Driver No 49 0.145 20 4 0.2 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0031325 Not Cancer Driver No 53 0.164 22 4 0.182 0
AP2M1_ENST00000292807 AP2M1 Q96CW1 AP-2 complex subunit mu chr3 GO:0031325 Not Cancer Driver No 55 0.126 41 9 0.22 1
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0031325 Not Cancer Driver No 127 0.102 17 1 0.059 0
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0031325 Not Cancer Driver No 1 0.019 0 0 0.0 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0031325 Not Cancer Driver No 64 0.125 407 57 0.14 0
APLN APLN Q9ULZ1 Apelin chrX GO:0031325 Not Cancer Driver No 8 0.104 51 6 0.118 0
APLNR APLNR P35414 Apelin receptor chr11 GO:0031325 Not Cancer Driver No 96 0.253 29 8 0.276 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0031325 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0031325 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0031325 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0031325 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC1_ENST00000588802 APOC1 P02654 Apolipoprotein C-I chr19 GO:0031325 Not Cancer Driver No 12 0.145 9 1 0.111 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0031325 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0031325 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0031325 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0031325 Not Cancer Driver No 67 0.094 292 31 0.106 1
AR AR P10275 Androgen receptor chrX GO:0031325 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARAF_ENST00000377045 ARAF P10398 Serine/threonine-protein kinase A-Raf chrX GO:0031325 Census, Compendium Yes 84 0.139 181 32 0.177 0
AREG AREG P15514 Amphiregulin chr4 GO:0031325 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0031325 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0031325 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARID2 ARID2 Q68CP9 AT-rich interactive domain-containing protein 2 chr12 GO:0031325 Census, Compendium Yes 272 0.148 1143 141 0.123 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0031325 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0031325 Census Yes 77 0.098 511 56 0.11 0
ARNTL ARNTL O00327 Aryl hydrocarbon receptor nuclear translocator-like protein 1 chr11 GO:0031325 Not Cancer Driver No 71 0.113 332 40 0.12 0
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0031325 Not Cancer Driver No 17 0.152 112 17 0.152 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0031325 Not Cancer Driver No 49 0.117 154 13 0.084 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0031325 Not Cancer Driver No 46 0.112 122 22 0.18 0
ARRDC3 ARRDC3 Q96B67 Arrestin domain-containing protein 3 chr5 GO:0031325 Not Cancer Driver No 52 0.126 95 12 0.126 0
ARRDC4 ARRDC4 Q8NCT1 Arrestin domain-containing protein 4 chr15 GO:0031325 Not Cancer Driver No 52 0.124 53 12 0.226 0
ASIP_ENST00000374954 ASIP P42127 Agouti-signaling protein chr20 GO:0031325 Not Cancer Driver No 16 0.121 36 9 0.25 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0031325 Not Cancer Driver No 109 0.144 373 53 0.142 1
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0031325 Not Cancer Driver No 65 0.158 63 8 0.127 86
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0031325 Not Cancer Driver No 101 0.234 179 44 0.246 0
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 GO:0031325 Not Cancer Driver No 32 0.089 71 3 0.042 0
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0031325 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0031325 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0031325 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0031325 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0031325 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0031325 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0031325 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 GO:0031325 Not Cancer Driver No 228 0.118 887 124 0.14 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0031325 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0031325 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0031325 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0031325 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0031325 Census, Compendium Yes 487 0.195 1672 301 0.18 33
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0031325 Not Cancer Driver No 46 0.127 181 24 0.133 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0031325 Not Cancer Driver No 51 0.148 63 8 0.127 0
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0031325 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0031325 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0031325 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0031325 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0031325 Census, Compendium Yes 120 0.139 619 88 0.142 4
AZU1 AZU1 P20160 Azurocidin chr19 GO:0031325 Not Cancer Driver No 42 0.167 53 13 0.245 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0031325 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 GO:0031325 Not Cancer Driver No 17 0.081 112 9 0.08 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0031325 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0031325 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0031325 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0031325 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0031325 Census Yes 30 0.156 39 2 0.051 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0031325 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0031325 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0031325 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0031325 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0031325 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0031325 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0031325 Census, Compendium Yes 134 0.19 328 67 0.204 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0031325 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0031325 Not Cancer Driver No 45 0.1 190 19 0.1 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0031325 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0031325 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0031325 Not Cancer Driver No 52 0.174 136 22 0.162 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 GO:0031325 Not Cancer Driver No 79 0.335 39 10 0.256 0
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0031325 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0031325 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0031325 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0031325 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0031325 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0031325 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0031325 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0031325 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0031325 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0031325 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0031325 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0031325 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0031325 Compendium Yes 141 0.136 601 70 0.116 19
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0031325 Not Cancer Driver No 195 0.196 530 111 0.209 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0031325 Not Cancer Driver No 16 0.073 175 14 0.08 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0031325 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0031325 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0031325 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0031325 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRD7_ENST00000394688 BRD7 Q9NPI1 Bromodomain-containing protein 7 chr16 GO:0031325 Compendium Yes 82 0.126 482 57 0.118 0
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0031325 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:0031325 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0031325 Not Cancer Driver No 90 0.133 399 45 0.113 4
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 GO:0031325 Not Cancer Driver No 42 0.171 115 18 0.157 0
BTC BTC P35070 Probetacellulin chr4 GO:0031325 Not Cancer Driver No 29 0.163 12 5 0.417 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0031325 Census Yes 32 0.203 7 2 0.286 0
BTRC BTRC Q9Y297 F-box/WD repeat-containing protein 1A chr10 GO:0031325 Not Cancer Driver No 80 0.132 45 4 0.089 0
BUD23_ENST00000265758 BUD23 O43709 Probable 18S rRNA (guanine-N(7))-methyltransferase chr7 GO:0031325 Not Cancer Driver No 41 0.146 83 11 0.133 0
BVES BVES Q8NE79 Blood vessel epicardial substance chr6 GO:0031325 Not Cancer Driver No 59 0.164 65 15 0.231 1
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0031325 Not Cancer Driver No 14 0.05 103 6 0.058 2
C6orf89_ENST00000480824 C6orf89 Q6UWU4 Bombesin receptor-activated protein C6orf89 chr6 GO:0031325 Not Cancer Driver No 38 0.11 29 2 0.069 0
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:0031325 Not Cancer Driver No 64 0.133 11 0 0.0 0
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0031325 Not Cancer Driver No 31 0.091 43 5 0.116 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 GO:0031325 Not Cancer Driver No 42 0.094 212 19 0.09 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0031325 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0031325 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0031325 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0031325 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMK1 CAMK1 Q14012 Calcium/calmodulin-dependent protein kinase type 1 chr3 GO:0031325 Not Cancer Driver No 40 0.108 31 1 0.032 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0031325 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0031325 Census, Compendium Yes 300 0.179 883 152 0.172 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0031325 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARD10_ENST00000251973 CARD10 Q9BWT7 Caspase recruitment domain-containing protein 10 chr22 GO:0031325 Not Cancer Driver No 94 0.091 474 40 0.084 0
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0031325 Not Cancer Driver No 99 0.099 296 36 0.122 11
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0031325 Not Cancer Driver No 93 0.128 503 63 0.125 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0031325 Census Yes 32 0.116 62 5 0.081 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0031325 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0031325 Census Yes 49 0.118 71 7 0.099 0
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0031325 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0031325 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0031325 Census Yes 160 0.163 562 104 0.185 0
CBR1 CBR1 P16152 Carbonyl reductase [NADPH] 1 chr21 GO:0031325 Not Cancer Driver No 27 0.097 62 11 0.177 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0031325 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0031325 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0031325 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0031325 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0031325 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCNB1 CCNB1 P14635 G2/mitotic-specific cyclin-B1 chr5 GO:0031325 Not Cancer Driver No 49 0.113 145 14 0.097 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0031325 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCND2 CCND2 P30279 G1/S-specific cyclin-D2 chr12 GO:0031325 Census, Compendium Yes 39 0.135 29 7 0.241 5
CCND3 CCND3 P30281 G1/S-specific cyclin-D3 chr6 GO:0031325 Census, Compendium Yes 29 0.099 46 8 0.174 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0031325 Not Cancer Driver No 39 0.067 347 15 0.043 1
CCNT1 CCNT1 O60563 Cyclin-T1 chr12 GO:0031325 Not Cancer Driver No 85 0.117 495 61 0.123 0
CCNT2 CCNT2 O60583 Cyclin-T2 chr2 GO:0031325 Not Cancer Driver No 76 0.104 471 52 0.11 0
CCNY CCNY Q8ND76 Cyclin-Y chr10 GO:0031325 Not Cancer Driver No 38 0.111 94 6 0.064 0
CCNYL1 CCNYL1 Q8N7R7 Cyclin-Y-like protein 1 chr2 GO:0031325 Not Cancer Driver No 31 0.086 100 8 0.08 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0031325 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0031325 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0031325 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0031325 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0031325 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0031325 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0031325 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0031325 Not Cancer Driver No 41 0.075 36 2 0.056 0
CD177 CD177 Q8N6Q3 CD177 antigen chr19 GO:0031325 Not Cancer Driver No 71 0.162 79 26 0.329 0
CD19_ENST00000324662 CD19 P15391 B-lymphocyte antigen CD19 chr16 GO:0031325 Not Cancer Driver No 80 0.144 312 46 0.147 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0031325 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0031325 Census Yes 42 0.191 18 10 0.556 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0031325 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD33 CD33 P20138 Myeloid cell surface antigen CD33 chr19 GO:0031325 Not Cancer Driver No 119 0.327 177 50 0.282 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0031325 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0031325 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD44 CD44 P16070 CD44 antigen chr11 GO:0031325 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0031325 Not Cancer Driver No 27 0.113 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0031325 Census Yes 31 0.105 185 20 0.108 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0031325 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD86 CD86 P42081 T-lymphocyte activation antigen CD86 chr3 GO:0031325 Not Cancer Driver No 90 0.274 56 18 0.321 0
CDC14B CDC14B O60729 Dual specificity protein phosphatase CDC14B chr9 GO:0031325 Not Cancer Driver No 61 0.122 138 15 0.109 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0031325 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0031325 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0031325 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0031325 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0031325 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDC73 CDC73 Q6P1J9 Parafibromin chr1 GO:0031325 Census, Compendium Yes 110 0.207 210 39 0.186 2
CDCA2 CDCA2 Q69YH5 Cell division cycle-associated protein 2 chr8 GO:0031325 Not Cancer Driver No 124 0.121 828 100 0.121 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0031325 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0031325 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0031325 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0031325 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0031325 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0031325 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0031325 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0031325 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDK9 CDK9 P50750 Cyclin-dependent kinase 9 chr9 GO:0031325 Not Cancer Driver No 50 0.134 34 2 0.059 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0031325 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0031325 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0031325 Not Cancer Driver No 60 0.11 377 35 0.093 5
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0031325 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0031325 Not Cancer Driver No 3 0.009 276 2 0.007 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0031325 Not Cancer Driver No 56 0.115 166 17 0.102 0
CELF3 CELF3 Q5SZQ8 CUGBP Elav-like family member 3 chr1 GO:0031325 Not Cancer Driver No 82 0.176 201 33 0.164 0
CELF4 CELF4 Q9BZC1 CUGBP Elav-like family member 4 chr18 GO:0031325 Not Cancer Driver No 107 0.22 253 74 0.292 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0031325 Not Cancer Driver No 207 0.152 105 10 0.095 0
CENPS CENPS Q8N2Z9 Centromere protein S chr1 GO:0031325 Not Cancer Driver No 16 0.116 65 7 0.108 0
CENPX_ENST00000392359 CENPX A8MT69 Centromere protein X chr17 GO:0031325 Not Cancer Driver No 4 0.049 0 0 0.0 0
CEP295 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 GO:0031325 Not Cancer Driver No 115 0.044 2026 87 0.043 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0031325 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0031325 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHCHD2 CHCHD2 Q9Y6H1 Coiled-coil-helix-coiled-coil-helix domain-containing protein 2 chr7 GO:0031325 Not Cancer Driver No 24 0.159 114 21 0.184 1
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0031325 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0031325 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHFR CHFR Q96EP1 E3 ubiquitin-protein ligase CHFR chr12 GO:0031325 Not Cancer Driver No 85 0.128 341 54 0.158 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0031325 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0031325 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0031325 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0031325 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0031325 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0031325 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0031325 Not Cancer Driver No 13 0.107 7 0 0.0 0
CHTOP_ENST00000368694 CHTOP Q9Y3Y2 Chromatin target of PRMT1 protein chr1 GO:0031325 Not Cancer Driver No 36 0.145 244 34 0.139 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0031325 Not Cancer Driver No 19 0.087 23 1 0.043 0
CIRBP_ENST00000586472 CIRBP Q14011 Cold-inducible RNA-binding protein chr19 GO:0031325 Not Cancer Driver No 19 0.11 129 13 0.101 0
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:0031325 Not Cancer Driver No 93 0.104 708 83 0.117 0
CKS1B CKS1B P61024 Cyclin-dependent kinases regulatory subunit 1 chr1 GO:0031325 Not Cancer Driver No 10 0.127 10 0 0.0 0
CKS2 CKS2 P33552 Cyclin-dependent kinases regulatory subunit 2 chr9 GO:0031325 Not Cancer Driver No 9 0.114 10 2 0.2 0
CLCF1 CLCF1 Q9UBD9 Cardiotrophin-like cytokine factor 1 chr11 GO:0031325 Not Cancer Driver No 22 0.098 42 4 0.095 1
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0031325 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0031325 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0031325 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLEC3B CLEC3B P05452 Tetranectin chr3 GO:0031325 Not Cancer Driver No 34 0.168 50 13 0.26 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0031325 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0031325 Not Cancer Driver No 69 0.154 156 27 0.173 0
CLYBL CLYBL Q8N0X4 Citramalyl-CoA lyase, mitochondrial chr13 GO:0031325 Not Cancer Driver No 48 0.141 0 0 0.0 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0031325 Census Yes 11 0.062 19 0 0.0 0
CNEP1R1_ENST00000427478 CNEP1R1 Q8N9A8 Nuclear envelope phosphatase-regulatory subunit 1 chr16 GO:0031325 Not Cancer Driver No 8 0.064 0 0 0.0 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0031325 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0031325 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0031325 Not Cancer Driver No 30 0.103 6 0 0.0 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0031325 Compendium Yes 42 0.14 30 0 0.0 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0031325 Not Cancer Driver No 155 0.149 370 61 0.165 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:0031325 Not Cancer Driver No 4 0.038 57 3 0.053 0
COMMD1 COMMD1 Q8N668 COMM domain-containing protein 1 chr2 GO:0031325 Not Cancer Driver No 21 0.111 17 0 0.0 0
COPS8 COPS8 Q99627 COP9 signalosome complex subunit 8 chr2 GO:0031325 Not Cancer Driver No 25 0.12 14 2 0.143 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0031325 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0031325 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0031325 Not Cancer Driver No 144 0.186 62 10 0.161 15
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0031325 Compendium Yes 383 0.188 151 42 0.278 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0031325 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0031325 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0031325 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0031325 Not Cancer Driver No 15 0.125 78 5 0.064 0
CRP CRP P02741 C-reactive protein chr1 GO:0031325 Not Cancer Driver No 59 0.263 0 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0031325 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0031325 Not Cancer Driver No 118 0.148 204 29 0.142 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0031325 Census Yes 133 0.137 124 17 0.137 20
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0031325 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0031325 Not Cancer Driver No 20 0.093 19 0 0.0 4
CTBP1 CTBP1 Q13363 C-terminal-binding protein 1 chr4 GO:0031325 Not Cancer Driver No 42 0.095 123 9 0.073 1
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:0031325 Not Cancer Driver No 20 0.082 0 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0031325 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTR9 CTR9 Q6PD62 RNA polymerase-associated protein CTR9 homolog chr11 GO:0031325 Not Cancer Driver No 164 0.14 385 48 0.125 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0031325 Census, Compendium Yes 123 0.16 167 23 0.138 3
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0031325 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0031325 Not Cancer Driver No 80 0.225 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0031325 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0031325 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0031325 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0031325 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0031325 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0031325 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 GO:0031325 Not Cancer Driver No 69 0.103 37 3 0.081 0
DAZAP1 DAZAP1 Q96EP5 DAZ-associated protein 1 chr19 GO:0031325 Compendium Yes 53 0.13 327 45 0.138 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 GO:0031325 Not Cancer Driver No 75 0.111 333 26 0.078 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0031325 Not Cancer Driver No 68 0.111 311 22 0.071 0
DCN DCN P07585 Decorin chr12 GO:0031325 Not Cancer Driver No 96 0.267 81 26 0.321 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0031325 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0031325 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0031325 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0031325 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0031325 Not Cancer Driver No 18 0.076 7 0 0.0 0
DCXR DCXR Q7Z4W1 L-xylulose reductase chr17 GO:0031325 Not Cancer Driver No 14 0.057 10 1 0.1 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0031325 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0031325 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0031325 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0031325 Census Yes 29 0.172 160 27 0.169 0
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0031325 Not Cancer Driver No 34 0.108 181 23 0.127 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0031325 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0031325 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0031325 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0031325 Census Yes 74 0.121 225 23 0.102 0
DEK DEK P35659 Protein DEK chr6 GO:0031325 Census Yes 47 0.125 297 41 0.138 0
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0031325 Not Cancer Driver No 28 0.112 11 1 0.091 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0031325 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0031325 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0031325 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHRS4 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 GO:0031325 Not Cancer Driver No 30 0.108 38 4 0.105 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0031325 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0031325 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0031325 Compendium Yes 182 0.143 331 42 0.127 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0031325 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIMT1 DIMT1 Q9UNQ2 Probable dimethyladenosine transferase chr5 GO:0031325 Not Cancer Driver No 28 0.089 37 2 0.054 0
DIP2A DIP2A Q14689 Disco-interacting protein 2 homolog A chr21 GO:0031325 Not Cancer Driver No 204 0.13 396 53 0.134 0
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0031325 Not Cancer Driver No 181 0.115 375 49 0.131 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0031325 Not Cancer Driver No 56 0.13 9 0 0.0 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0031325 Not Cancer Driver No 114 0.129 264 22 0.083 1
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0031325 Not Cancer Driver No 62 0.121 145 29 0.2 24
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0031325 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0031325 Not Cancer Driver No 331 0.217 922 237 0.257 0
DLG3 DLG3 Q92796 Disks large homolog 3 chrX GO:0031325 Not Cancer Driver No 94 0.115 322 30 0.093 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0031325 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0031325 Not Cancer Driver No 71 0.246 223 57 0.256 1
DMAP1_ENST00000315913 DMAP1 Q9NPF5 DNA methyltransferase 1-associated protein 1 chr1 GO:0031325 Not Cancer Driver No 49 0.105 269 28 0.104 0
DMRTC2 DMRTC2 Q8IXT2 Doublesex- and mab-3-related transcription factor C2 chr19 GO:0031325 Not Cancer Driver No 45 0.123 310 35 0.113 0
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0031325 Not Cancer Driver No 60 0.119 131 17 0.13 0
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:0031325 Not Cancer Driver No 23 0.065 36 0 0.0 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0031325 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0031325 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3B DNMT3B Q9UBC3 DNA (cytosine-5)-methyltransferase 3B chr20 GO:0031325 Not Cancer Driver No 153 0.179 328 71 0.216 16
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0031325 Not Cancer Driver No 83 0.215 10 1 0.1 0
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0031325 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0031325 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOK7 DOK7 Q18PE1 Protein Dok-7 chr4 GO:0031325 Not Cancer Driver No 52 0.103 286 27 0.094 19
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0031325 Not Cancer Driver No 127 0.287 124 45 0.363 0
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0031325 Not Cancer Driver No 28 0.071 41 4 0.098 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0031325 Not Cancer Driver No 49 0.14 210 25 0.119 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0031325 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUOXA1_ENST00000560572 DUOXA1 Q1HG43 Dual oxidase maturation factor 1 chr15 GO:0031325 Not Cancer Driver No 40 0.117 38 7 0.184 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 GO:0031325 Not Cancer Driver No 40 0.125 0 0 0.0 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0031325 Not Cancer Driver No 33 0.097 30 1 0.033 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0031325 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0031325 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0031325 Not Cancer Driver No 97 0.135 437 58 0.133 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0031325 Not Cancer Driver No 46 0.116 143 17 0.119 0
DYNAP DYNAP Q8N1N2 Dynactin-associated protein chr18 GO:0031325 Not Cancer Driver No 54 0.257 78 21 0.269 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0031325 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0031325 Not Cancer Driver No 77 0.128 294 39 0.133 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0031325 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0031325 Not Cancer Driver No 132 0.152 582 85 0.146 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0031325 Not Cancer Driver No 118 0.153 99 26 0.263 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0031325 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1A2 EEF1A2 Q05639 Elongation factor 1-alpha 2 chr20 GO:0031325 Not Cancer Driver No 74 0.16 121 17 0.14 3
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0031325 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0031325 Not Cancer Driver No 24 0.101 31 11 0.355 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0031325 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0031325 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0031325 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0031325 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0031325 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0031325 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:0031325 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:0031325 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0031325 Not Cancer Driver No 116 0.118 899 101 0.112 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0031325 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0031325 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:0031325 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0031325 Not Cancer Driver No 37 0.24 21 5 0.238 5
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0031325 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0031325 Not Cancer Driver No 34 0.114 25 4 0.16 2
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0031325 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0031325 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0031325 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0031325 Not Cancer Driver No 102 0.223 65 19 0.292 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0031325 Not Cancer Driver No 41 0.096 6 1 0.167 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0031325 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EP400 EP400 Q96L91 E1A-binding protein p400 chr12 GO:0031325 Not Cancer Driver No 397 0.126 2064 234 0.113 0
EPC1 EPC1 Q9H2F5 Enhancer of polycomb homolog 1 chr10 GO:0031325 Not Cancer Driver No 104 0.124 515 68 0.132 0
EPC2 EPC2 Q52LR7 Enhancer of polycomb homolog 2 chr2 GO:0031325 Not Cancer Driver No 95 0.118 583 67 0.115 0
EPGN EPGN Q6UW88 Epigen chr4 GO:0031325 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0031325 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0031325 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0031325 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0031325 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0031325 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0031325 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0031325 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0031325 Not Cancer Driver No 211 0.141 829 117 0.141 9
EREG EREG O14944 Proepiregulin chr4 GO:0031325 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0031325 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0031325 Not Cancer Driver No 192 0.207 213 45 0.211 0
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0031325 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0031325 Not Cancer Driver No 68 0.154 78 9 0.115 0
EXOSC3 EXOSC3 Q9NQT5 Exosome complex component RRP40 chr9 GO:0031325 Not Cancer Driver No 18 0.065 54 2 0.037 4
EXOSC6 EXOSC6 Q5RKV6 Exosome complex component MTR3 chr16 GO:0031325 Not Cancer Driver No 3 0.011 102 0 0.0 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0031325 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0031325 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0031325 Not Cancer Driver No 58 0.132 154 18 0.117 1
F12 F12 P00748 Coagulation factor XII chr5 GO:0031325 Not Cancer Driver No 53 0.086 104 9 0.087 13
F2 F2 P00734 Prothrombin chr11 GO:0031325 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0031325 Not Cancer Driver No 55 0.139 7 2 0.286 0
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0031325 Not Cancer Driver No 34 0.268 0 0 0.0 0
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0031325 Not Cancer Driver No 22 0.165 3 0 0.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0031325 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0031325 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM161A_ENST00000405894 FAM161A Q3B820 Protein FAM161A chr2 GO:0031325 Not Cancer Driver No 102 0.155 510 83 0.163 0
FAM168A FAM168A Q92567 Protein FAM168A chr11 GO:0031325 Not Cancer Driver No 17 0.07 139 11 0.079 0
FAM47E FAM47E Q6ZV65 Protein FAM47E chr4 GO:0031325 Not Cancer Driver No 21 0.053 143 6 0.042 0
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0031325 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 GO:0031325 Not Cancer Driver No 161 0.121 129 20 0.155 2
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0031325 Not Cancer Driver No 268 0.131 898 128 0.143 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0031325 Census, Compendium Yes 55 0.164 62 18 0.29 22
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0031325 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:0031325 Not Cancer Driver No 106 0.16 6 1 0.167 0
FBXO33 FBXO33 Q7Z6M2 F-box only protein 33 chr14 GO:0031325 Not Cancer Driver No 38 0.068 30 2 0.067 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0031325 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0031325 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0031325 Census, Compendium Yes 322 0.455 230 38 0.165 0
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0031325 Not Cancer Driver No 68 0.114 120 4 0.033 0
FCGR1A FCGR1A P12314 High affinity immunoglobulin gamma Fc receptor I chr1 GO:0031325 Not Cancer Driver No 62 0.166 37 5 0.135 0
FCRL3_ENST00000368184 FCRL3 Q96P31 Fc receptor-like protein 3 chr1 GO:0031325 Not Cancer Driver No 193 0.263 217 44 0.203 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0031325 Not Cancer Driver No 71 0.104 101 10 0.099 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0031325 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0031325 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0031325 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0031325 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR3_ENST00000440486 FGFR3 P22607 Fibroblast growth factor receptor 3 chr4 GO:0031325 Census, Compendium Yes 173 0.215 241 26 0.108 37
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0031325 Census, Compendium Yes 113 0.141 162 28 0.173 0
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0031325 Not Cancer Driver No 85 0.161 52 8 0.154 0
FKBP1A FKBP1A P62942 Peptidyl-prolyl cis-trans isomerase FKBP1A chr20 GO:0031325 Not Cancer Driver No 15 0.139 39 7 0.179 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0031325 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0031325 Census, Compendium Yes 200 0.201 64 27 0.422 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0031325 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0031325 Not Cancer Driver No 124 0.196 327 70 0.214 3
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0031325 Not Cancer Driver No 143 0.123 384 44 0.115 0
FNIP2 FNIP2 Q9P278 Folliculin-interacting protein 2 chr4 GO:0031325 Not Cancer Driver No 119 0.107 555 71 0.128 0
FNTA FNTA P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha chr8 GO:0031325 Not Cancer Driver No 43 0.113 92 12 0.13 0
FOS FOS P01100 Protein c-Fos chr14 GO:0031325 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0031325 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0031325 Compendium Yes 70 0.153 258 34 0.132 0
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0031325 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0031325 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0031325 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0031325 Not Cancer Driver No 38 0.088 186 16 0.086 10
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0031325 Not Cancer Driver No 96 0.274 26 5 0.192 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0031325 Not Cancer Driver No 67 0.133 53 10 0.189 3
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0031325 Not Cancer Driver No 93 0.117 283 35 0.124 0
FUS FUS P35637 RNA-binding protein FUS chr16 GO:0031325 Census Yes 51 0.097 524 51 0.097 20
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 GO:0031325 Not Cancer Driver No 181 0.122 892 106 0.119 1
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0031325 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0031325 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0031325 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0031325 Not Cancer Driver No 72 0.104 146 3 0.021 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0031325 Not Cancer Driver No 74 0.149 184 30 0.163 0
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0031325 Not Cancer Driver No 9 0.077 11 0 0.0 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0031325 Not Cancer Driver No 10 0.061 39 5 0.128 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 GO:0031325 Not Cancer Driver No 71 0.174 111 19 0.171 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0031325 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0031325 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0031325 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0031325 Not Cancer Driver No 40 0.101 268 24 0.09 9
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0031325 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCG GCG P01275 Pro-glucagon chr2 GO:0031325 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0031325 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0031325 Not Cancer Driver No 327 0.122 117 16 0.137 0
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0031325 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0031325 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0031325 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0031325 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0031325 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0031325 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0031325 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0031325 Not Cancer Driver No 72 0.159 53 15 0.283 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0031325 Not Cancer Driver No 10 0.049 97 4 0.041 1
GH1 GH1 P01241 Somatotropin chr17 GO:0031325 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0031325 Not Cancer Driver No 50 0.145 8 0 0.0 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0031325 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0031325 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0031325 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0031325 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0031325 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0031325 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0031325 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0031325 Not Cancer Driver No 32 0.143 77 14 0.182 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0031325 Not Cancer Driver No 47 0.141 138 17 0.123 0
GLYR1 GLYR1 Q49A26 Putative oxidoreductase GLYR1 chr16 GO:0031325 Not Cancer Driver No 87 0.157 201 27 0.134 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0031325 Not Cancer Driver No 41 0.108 20 0 0.0 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0031325 Compendium Yes 50 0.141 24 0 0.0 0
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0031325 Not Cancer Driver No 42 0.119 11 0 0.0 1
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0031325 Not Cancer Driver No 56 0.102 257 21 0.082 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0031325 Not Cancer Driver No 115 0.115 854 96 0.112 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0031325 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0031325 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0031325 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0031325 Not Cancer Driver No 89 0.156 94 18 0.191 0
GPR37 GPR37 O15354 Prosaposin receptor GPR37 chr7 GO:0031325 Not Cancer Driver No 124 0.202 200 42 0.21 0
GPRC5B_ENST00000569479 GPRC5B Q9NZH0 G-protein coupled receptor family C group 5 member B chr16 GO:0031325 Not Cancer Driver No 82 0.203 75 19 0.253 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 GO:0031325 Not Cancer Driver No 68 0.101 344 35 0.102 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 GO:0031325 Not Cancer Driver No 52 0.105 51 9 0.176 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0031325 Not Cancer Driver No 28 0.129 10 1 0.1 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0031325 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0031325 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0031325 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0031325 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0031325 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRN GRN P28799 Progranulin chr17 GO:0031325 Not Cancer Driver No 76 0.128 29 6 0.207 1
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 GO:0031325 Not Cancer Driver No 49 0.102 147 20 0.136 0
GSAP GSAP A4D1B5 Gamma-secretase-activating protein chr7 GO:0031325 Not Cancer Driver No 89 0.104 13 0 0.0 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0031325 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSN GSN P06396 Gelsolin chr9 GO:0031325 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0031325 Not Cancer Driver No 32 0.152 0 0 0.0 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0031325 Not Cancer Driver No 75 0.112 263 26 0.099 0
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0031325 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0031325 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0031325 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0031325 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0031325 Not Cancer Driver No 17 0.152 0 0 0.0 0
HABP4 HABP4 Q5JVS0 Intracellular hyaluronan-binding protein 4 chr9 GO:0031325 Not Cancer Driver No 32 0.077 413 32 0.077 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0031325 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0031325 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0031325 Not Cancer Driver No 45 0.306 7 2 0.286 5
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0031325 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCFC1 HCFC1 P51610 Host cell factor 1 chrX GO:0031325 Not Cancer Driver No 280 0.138 1345 181 0.135 1
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0031325 Not Cancer Driver No 103 0.212 446 94 0.211 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0031325 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0031325 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC4 HDAC4 P56524 Histone deacetylase 4 chr2 GO:0031325 Not Cancer Driver No 182 0.168 749 132 0.176 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0031325 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL2 HDGFL2 Q7Z4V5 Hepatoma-derived growth factor-related protein 2 chr19 GO:0031325 Not Cancer Driver No 59 0.088 622 57 0.092 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:0031325 Not Cancer Driver No 291 0.136 43 5 0.116 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0031325 Census Yes 38 0.097 248 17 0.069 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0031325 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0031325 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0031325 Census Yes 118 0.143 435 51 0.117 0
HIST1H1B H1-5 P16401 Histone H1.5 chr6 GO:0031325 Not Cancer Driver No 66 0.292 224 66 0.295 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0031325 Not Cancer Driver No 55 0.131 319 41 0.129 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0031325 Not Cancer Driver No 37 0.105 131 16 0.122 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0031325 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMGB2 HMGB2 P26583 High mobility group protein B2 chr4 GO:0031325 Not Cancer Driver No 38 0.182 207 38 0.184 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0031325 Not Cancer Driver No 46 0.16 81 13 0.16 0
HMX2 HMX2 A2RU54 Homeobox protein HMX2 chr10 GO:0031325 Not Cancer Driver No 36 0.132 169 21 0.124 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0031325 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0031325 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0031325 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPLL HNRNPLL Q8WVV9 Heterogeneous nuclear ribonucleoprotein L-like chr2 GO:0031325 Not Cancer Driver No 37 0.068 149 13 0.087 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0031325 Not Cancer Driver No 77 0.093 504 45 0.089 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0031325 Not Cancer Driver No 60 0.144 12 0 0.0 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0031325 Not Cancer Driver No 22 0.101 3 0 0.0 62
HRAS HRAS P01112 GTPase HRas chr11 GO:0031325 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0031325 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0031325 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0031325 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0031325 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0031325 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0031325 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0031325 Not Cancer Driver No 149 0.231 251 52 0.207 0
HSPB8 HSPB8 Q9UJY1 Heat shock protein beta-8 chr12 GO:0031325 Not Cancer Driver No 40 0.204 130 31 0.238 5
HSPBP1 HSPBP1 Q9NZL4 Hsp70-binding protein 1 chr19 GO:0031325 Not Cancer Driver No 29 0.081 130 7 0.054 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0031325 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0031325 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0031325 Not Cancer Driver No 140 0.306 40 11 0.275 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0031325 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0031325 Not Cancer Driver No 336 0.107 666 69 0.104 2
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0031325 Not Cancer Driver No 669 0.153 2091 329 0.157 21
HVCN1_ENST00000620084 HVCN1 Q96D96 Voltage-gated hydrogen channel 1 chr12 GO:0031325 Not Cancer Driver No 51 0.187 52 13 0.25 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0031325 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0031325 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0031325 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0031325 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNA10 IFNA10 P01566 Interferon alpha-10 chr9 GO:0031325 Not Cancer Driver No 40 0.212 1 0 0.0 0
IFNA13_ENST00000449498 IFNA13 P01562 Interferon alpha-1/13 chr9 GO:0031325 Not Cancer Driver No 39 0.206 2 0 0.0 0
IFNA14 IFNA14 P01570 Interferon alpha-14 chr9 GO:0031325 Not Cancer Driver No 39 0.206 1 1 1.0 0
IFNA16 IFNA16 P05015 Interferon alpha-16 chr9 GO:0031325 Not Cancer Driver No 61 0.323 1 0 0.0 0
IFNA17 IFNA17 P01571 Interferon alpha-17 chr9 GO:0031325 Not Cancer Driver No 37 0.196 0 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0031325 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNA21 IFNA21 P01568 Interferon alpha-21 chr9 GO:0031325 Not Cancer Driver No 34 0.18 0 0 0.0 0
IFNA4 IFNA4 P05014 Interferon alpha-4 chr9 GO:0031325 Not Cancer Driver No 39 0.206 1 0 0.0 0
IFNA5 IFNA5 P01569 Interferon alpha-5 chr9 GO:0031325 Not Cancer Driver No 36 0.19 1 0 0.0 0
IFNA6 IFNA6 P05013 Interferon alpha-6 chr9 GO:0031325 Not Cancer Driver No 28 0.148 4 0 0.0 0
IFNA7 IFNA7 P01567 Interferon alpha-7 chr9 GO:0031325 Not Cancer Driver No 43 0.228 1 1 1.0 0
IFNA8 IFNA8 P32881 Interferon alpha-8 chr9 GO:0031325 Not Cancer Driver No 43 0.228 0 0 0.0 0
IFNAR1 IFNAR1 P17181 Interferon alpha/beta receptor 1 chr21 GO:0031325 Compendium Yes 55 0.099 50 6 0.12 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0031325 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNE IFNE Q86WN2 Interferon epsilon chr9 GO:0031325 Not Cancer Driver No 30 0.144 17 4 0.235 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0031325 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNGR1 IFNGR1 P15260 Interferon gamma receptor 1 chr6 GO:0031325 Compendium Yes 55 0.112 175 22 0.126 10
IFNK IFNK Q9P0W0 Interferon kappa chr9 GO:0031325 Not Cancer Driver No 17 0.082 23 0 0.0 0
IFNLR1 IFNLR1 Q8IU57 Interferon lambda receptor 1 chr1 GO:0031325 Not Cancer Driver No 57 0.11 256 33 0.129 0
IFNW1 IFNW1 P05000 Interferon omega-1 chr9 GO:0031325 Not Cancer Driver No 32 0.164 10 3 0.3 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0031325 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0031325 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0031325 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0031325 Not Cancer Driver No 39 0.217 44 12 0.273 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0031325 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:0031325 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL10RB IL10RB Q08334 Interleukin-10 receptor subunit beta chr21 GO:0031325 Not Cancer Driver No 52 0.16 39 5 0.128 0
IL11 IL11 P20809 Interleukin-11 chr19 GO:0031325 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0031325 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0031325 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0031325 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0031325 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0031325 Census Yes 24 0.157 6 1 0.167 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0031325 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL23R IL23R Q5VWK5 Interleukin-23 receptor chr1 GO:0031325 Not Cancer Driver No 70 0.111 117 19 0.162 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0031325 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0031325 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0031325 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0031325 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0031325 Not Cancer Driver No 55 0.118 165 23 0.139 1
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0031325 Not Cancer Driver No 49 0.153 84 12 0.143 0
INAVA_ENST00000367342 INAVA Q3KP66 Innate immunity activator protein chr1 GO:0031325 Not Cancer Driver No 112 0.169 553 98 0.177 1
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0031325 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING3 ING3 Q9NXR8 Inhibitor of growth protein 3 chr7 GO:0031325 Not Cancer Driver No 44 0.105 292 32 0.11 1
INHA INHA P05111 Inhibin alpha chain chr2 GO:0031325 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0031325 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0031325 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0031325 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0031325 Not Cancer Driver No 52 0.149 85 12 0.141 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0031325 Compendium Yes 173 0.111 682 76 0.111 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0031325 Not Cancer Driver No 138 0.122 394 45 0.114 0
INS INS P01308 Insulin chr11 GO:0031325 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0031325 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0031325 Not Cancer Driver No 55 0.112 43 3 0.07 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0031325 Compendium Yes 71 0.1 337 39 0.116 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0031325 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0031325 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0031325 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISCU ISCU Q9H1K1 Iron-sulfur cluster assembly enzyme ISCU, mitochondrial chr12 GO:0031325 Not Cancer Driver No 14 0.084 24 3 0.125 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0031325 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0031325 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGA1 ITGA1 P56199 Integrin alpha-1 chr5 GO:0031325 Not Cancer Driver No 156 0.132 107 13 0.121 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0031325 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0031325 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0031325 Not Cancer Driver No 191 0.166 133 12 0.09 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0031325 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0031325 Not Cancer Driver No 147 0.191 59 9 0.153 15
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0031325 Census, Compendium Yes 136 0.12 59 5 0.085 5
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0031325 Not Cancer Driver No 190 0.152 724 113 0.156 0
JDP2_ENST00000435893 JDP2 Q8WYK2 Jun dimerization protein 2 chr14 GO:0031325 Not Cancer Driver No 16 0.098 142 13 0.092 0
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0031325 Not Cancer Driver No 67 0.145 19 5 0.263 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0031325 Census Yes 35 0.106 281 25 0.089 0
KANSL1_ENST00000262419 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 GO:0031325 Not Cancer Driver No 168 0.152 876 130 0.148 0
KANSL2 KANSL2 Q9H9L4 KAT8 regulatory NSL complex subunit 2 chr12 GO:0031325 Not Cancer Driver No 53 0.108 304 27 0.089 0
KANSL3 KANSL3 Q9P2N6 KAT8 regulatory NSL complex subunit 3 chr2 GO:0031325 Not Cancer Driver No 92 0.102 547 62 0.113 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0031325 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0031325 Not Cancer Driver No 107 0.129 266 27 0.102 0
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0031325 Not Cancer Driver No 65 0.127 173 21 0.121 3
KAT7 KAT7 O95251 Histone acetyltransferase KAT7 chr17 GO:0031325 Census Yes 97 0.159 327 47 0.144 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:0031325 Not Cancer Driver No 66 0.144 156 20 0.128 4
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0031325 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0031325 Not Cancer Driver No 78 0.149 215 33 0.153 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0031325 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0031325 Not Cancer Driver No 68 0.313 121 43 0.355 0
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0031325 Not Cancer Driver No 84 0.118 684 81 0.118 0
KIAA1324 ELAPOR1 Q6UXG2 Endosome/lysosome-associated apoptosis and autophagy regulator 1 chr1 GO:0031325 Not Cancer Driver No 94 0.093 56 5 0.089 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0031325 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0031325 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0031325 Compendium Yes 77 0.168 366 40 0.109 0
KLHL40 KLHL40 Q2TBA0 Kelch-like protein 40 chr3 GO:0031325 Not Cancer Driver No 108 0.174 44 8 0.182 13
KLKB1 KLKB1 P03952 Plasma kallikrein chr4 GO:0031325 Not Cancer Driver No 117 0.183 24 1 0.042 3
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0031325 Not Cancer Driver No 38 0.176 0 0 0.0 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0031325 Census, Compendium Yes 446 0.112 3145 338 0.107 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0031325 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KMT5B_ENST00000615954 KMT5B Q4FZB7 Histone-lysine N-methyltransferase KMT5B chr11 GO:0031325 Not Cancer Driver No 147 0.166 659 113 0.171 0
KMT5C KMT5C Q86Y97 Histone-lysine N-methyltransferase KMT5C chr19 GO:0031325 Not Cancer Driver No 37 0.08 142 9 0.063 0
KPNA7 KPNA7 A9QM74 Importin subunit alpha-8 chr7 GO:0031325 Not Cancer Driver No 36 0.07 66 2 0.03 0
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0031325 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0031325 Not Cancer Driver No 46 0.176 16 6 0.375 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0031325 Not Cancer Driver No 58 0.1 350 44 0.126 0
LATS1 LATS1 O95835 Serine/threonine-protein kinase LATS1 chr6 GO:0031325 Census, Compendium Yes 161 0.142 788 100 0.127 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0031325 Compendium Yes 56 0.136 177 29 0.164 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0031325 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0031325 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0031325 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0031325 Not Cancer Driver No 74 0.111 611 69 0.113 0
LEP LEP P41159 Leptin chr7 GO:0031325 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0031325 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0031325 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0031325 Not Cancer Driver No 181 0.259 12 8 0.667 25
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0031325 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRA5 LILRA5 A6NI73 Leukocyte immunoglobulin-like receptor subfamily A member 5 chr19 GO:0031325 Not Cancer Driver No 79 0.264 98 19 0.194 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0031325 Not Cancer Driver No 148 0.248 235 50 0.213 0
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0031325 Not Cancer Driver No 37 0.177 86 12 0.14 0
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0031325 Not Cancer Driver No 60 0.24 179 32 0.179 0
LIPT2 LIPT2 A6NK58 Putative lipoyltransferase 2, mitochondrial chr11 GO:0031325 Not Cancer Driver No 4 0.017 14 0 0.0 3
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0031325 Census Yes 68 0.102 544 49 0.09 131
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0031325 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPGAT1 LPGAT1 Q92604 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 chr1 GO:0031325 Not Cancer Driver No 38 0.103 11 0 0.0 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0031325 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0031325 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0031325 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0031325 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRRTM3 LRRTM3 Q86VH5 Leucine-rich repeat transmembrane neuronal protein 3 chr10 GO:0031325 Not Cancer Driver No 142 0.244 136 31 0.228 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0031325 Not Cancer Driver No 86 0.119 240 30 0.125 1
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0031325 Not Cancer Driver No 50 0.132 249 31 0.124 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0031325 Census Yes 95 0.186 84 12 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0031325 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAGEC2 MAGEC2 Q9UBF1 Melanoma-associated antigen C2 chrX GO:0031325 Not Cancer Driver No 170 0.456 129 69 0.535 0
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0031325 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MALT1 MALT1 Q9UDY8 Mucosa-associated lymphoid tissue lymphoma translocation protein 1 chr18 GO:0031325 Census, Compendium Yes 75 0.091 139 12 0.086 1
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0031325 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0031325 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0031325 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0031325 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0031325 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP2K2 MAP2K2 P36507 Dual specificity mitogen-activated protein kinase kinase 2 chr19 GO:0031325 Census Yes 58 0.145 105 14 0.133 4
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0031325 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0031325 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0031325 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0031325 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0031325 Census Yes 157 0.163 593 91 0.153 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0031325 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0031325 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0031325 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0031325 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0031325 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0031325 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0031325 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0031325 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0031325 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0031325 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0031325 Not Cancer Driver No 70 0.134 173 25 0.145 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0031325 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPRE3 MAPRE3 Q9UPY8 Microtubule-associated protein RP/EB family member 3 chr2 GO:0031325 Not Cancer Driver No 37 0.132 120 16 0.133 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0031325 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0031325 Not Cancer Driver No 33 0.134 23 5 0.217 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0031325 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0031325 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0031325 Not Cancer Driver No 47 0.145 5 2 0.4 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0031325 Not Cancer Driver No 90 0.102 389 44 0.113 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0031325 Not Cancer Driver No 52 0.171 304 52 0.171 0
MBTD1_ENST00000415868 MBTD1 Q05BQ5 MBT domain-containing protein 1 chr17 GO:0031325 Not Cancer Driver No 66 0.105 119 8 0.067 0
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0031325 Not Cancer Driver No 63 0.121 16 4 0.25 9
MCRS1_ENST00000550165 MCRS1 Q96EZ8 Microspherule protein 1 chr12 GO:0031325 Not Cancer Driver No 72 0.156 151 18 0.119 0
MEAF6_ENST00000296214 MEAF6 Q9HAF1 Chromatin modification-related protein MEAF6 chr1 GO:0031325 Not Cancer Driver No 22 0.115 171 21 0.123 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0031325 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0031325 Not Cancer Driver No 92 0.195 408 81 0.199 0
MELTF MELTF P08582 Melanotransferrin chr3 GO:0031325 Not Cancer Driver No 106 0.144 23 6 0.261 0
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0031325 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0031325 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0031325 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0031325 Not Cancer Driver No 74 0.128 274 29 0.106 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:0031325 Not Cancer Driver No 35 0.054 501 24 0.048 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0031325 Not Cancer Driver No 61 0.112 36 4 0.111 7
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0031325 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0031325 Not Cancer Driver No 23 0.126 83 6 0.072 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0031325 Not Cancer Driver No 4 0.035 0 0 0.0 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0031325 Not Cancer Driver No 45 0.108 145 16 0.11 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0031325 Census Yes 92 0.122 208 22 0.106 85
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0031325 Not Cancer Driver No 106 0.124 554 66 0.119 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0031325 Not Cancer Driver No 41 0.083 82 0 0.0 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0031325 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0031325 Not Cancer Driver No 73 0.156 115 19 0.165 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0031325 Not Cancer Driver No 73 0.071 11 0 0.0 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0031325 Not Cancer Driver No 23 0.074 64 2 0.031 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0031325 Not Cancer Driver No 48 0.137 47 8 0.17 0
MORF4L1 MORF4L1 Q9UBU8 Mortality factor 4-like protein 1 chr15 GO:0031325 Not Cancer Driver No 43 0.119 163 17 0.104 0
MORF4L2_ENST00000433176 MORF4L2 Q15014 Mortality factor 4-like protein 2 chrX GO:0031325 Not Cancer Driver No 44 0.153 136 21 0.154 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0031325 Not Cancer Driver No 110 0.11 101 8 0.079 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:0031325 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0031325 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRGBP MRGBP Q9NV56 MRG/MORF4L-binding protein chr20 GO:0031325 Not Cancer Driver No 27 0.132 147 23 0.156 0
MRNIP MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0031325 Not Cancer Driver No 44 0.128 268 35 0.131 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0031325 Not Cancer Driver No 46 0.111 51 7 0.137 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:0031325 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0031325 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0031325 Census Yes 92 0.099 37 4 0.108 70
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0031325 Not Cancer Driver No 68 0.181 64 11 0.172 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0031325 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:0031325 Not Cancer Driver No 92 0.129 327 42 0.128 0
MTCP1_ENST00000362018 MTCP1 P56278 Protein p13 MTCP-1 chrX GO:0031325 Census, Compendium Yes 14 0.131 6 0 0.0 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 GO:0031325 Not Cancer Driver No 70 0.118 225 28 0.124 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0031325 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0031325 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0031325 Census Yes 40 0.032 1050 19 0.018 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0031325 Not Cancer Driver No 48 0.136 16 2 0.125 0
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0031325 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0031325 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYB_ENST00000367814 MYB P10242 Transcriptional activator Myb chr6 GO:0031325 Census Yes 82 0.128 528 69 0.131 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0031325 Not Cancer Driver No 608 0.13 1398 189 0.135 0
MYCN MYCN P04198 N-myc proto-oncogene protein chr2 GO:0031325 Census, Compendium Yes 71 0.153 415 64 0.154 3
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0031325 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0031325 Census, Compendium Yes 310 0.158 1120 160 0.143 17
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0031325 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0031325 Census Yes 45 0.141 246 33 0.134 0
NAB2 NAB2 Q15742 NGFI-A-binding protein 2 chr12 GO:0031325 Census Yes 67 0.128 395 51 0.129 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0031325 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0031325 Not Cancer Driver No 61 0.123 386 44 0.114 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0031325 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0031325 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0031325 Not Cancer Driver No 31 0.179 117 25 0.214 0
NAP1L2 NAP1L2 Q9ULW6 Nucleosome assembly protein 1-like 2 chrX GO:0031325 Not Cancer Driver No 124 0.27 178 55 0.309 0
NBN NBN O60934 Nibrin chr8 GO:0031325 Census Yes 90 0.119 417 54 0.129 1
NCBP1 NCBP1 Q09161 Nuclear cap-binding protein subunit 1 chr9 GO:0031325 Not Cancer Driver No 88 0.111 89 8 0.09 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0031325 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0031325 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0031325 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCL NCL P19338 Nucleolin chr2 GO:0031325 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0031325 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0031325 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDFIP1 NDFIP1 Q9BT67 NEDD4 family-interacting protein 1 chr5 GO:0031325 Not Cancer Driver No 22 0.1 44 4 0.091 0
NDFIP2_ENST00000218652 NDFIP2 Q9NV92 NEDD4 family-interacting protein 2 chr13 GO:0031325 Not Cancer Driver No 27 0.08 198 13 0.066 0
NDN NDN Q99608 Necdin chr15 GO:0031325 Not Cancer Driver No 123 0.383 117 42 0.359 0
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0031325 Not Cancer Driver No 106 0.127 516 72 0.14 0
NEK10_ENST00000429845 NEK10 Q6ZWH5 Serine/threonine-protein kinase Nek10 chr3 GO:0031325 Not Cancer Driver No 213 0.182 281 60 0.214 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0031325 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0031325 Not Cancer Driver No 35 0.116 23 0 0.0 0
NELFA_ENST00000411638 NELFA Q9H3P2 Negative elongation factor A chr4 GO:0031325 Not Cancer Driver No 68 0.129 373 58 0.155 0
NELFE NELFE P18615 Negative elongation factor E chr6 GO:0031325 Not Cancer Driver No 47 0.124 352 45 0.128 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0031325 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0031325 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0031325 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0031325 Not Cancer Driver No 66 0.274 93 25 0.269 1
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0031325 Not Cancer Driver No 57 0.133 172 25 0.145 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0031325 Not Cancer Driver No 26 0.089 215 21 0.098 0
NHLRC1 NHLRC1 Q6VVB1 E3 ubiquitin-protein ligase NHLRC1 chr6 GO:0031325 Not Cancer Driver No 66 0.167 18 3 0.167 22
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0031325 Compendium Yes 353 0.126 1528 184 0.12 37
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0031325 Not Cancer Driver No 64 0.142 451 64 0.142 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0031325 Not Cancer Driver No 48 0.148 181 22 0.122 55
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0031325 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0031325 Not Cancer Driver No 106 0.119 203 28 0.138 0
NMI NMI Q13287 N-myc-interactor chr2 GO:0031325 Not Cancer Driver No 34 0.111 104 12 0.115 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0031325 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0031325 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0031325 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0031325 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:0031325 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0031325 Not Cancer Driver No 59 0.123 391 41 0.105 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0031325 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0031325 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0031325 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0031325 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0031325 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0031325 Not Cancer Driver No 336 0.168 464 79 0.17 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0031325 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0031325 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0031325 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0031325 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0031325 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0031325 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0031325 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0031325 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0031325 Census Yes 83 0.133 298 37 0.124 0
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0031325 Not Cancer Driver No 162 0.141 253 34 0.134 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0031325 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0031325 Not Cancer Driver No 227 0.315 425 134 0.315 0
NSD2_ENST00000382892 NSD2 O96028 Histone-lysine N-methyltransferase NSD2 chr4 GO:0031325 Census, Compendium Yes 191 0.14 552 76 0.138 0
NSD3 NSD3 Q9BZ95 Histone-lysine N-methyltransferase NSD3 chr8 GO:0031325 Census Yes 164 0.114 679 98 0.144 0
NSF NSF P46459 Vesicle-fusing ATPase chr17 GO:0031325 Not Cancer Driver No 47 0.063 84 3 0.036 2
NSG1_ENST00000513555 NSG1 P42857 Neuronal vesicle trafficking-associated protein 1 chr4 GO:0031325 Not Cancer Driver No 36 0.195 29 9 0.31 0
NSMCE3 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:0031325 Not Cancer Driver No 33 0.109 128 7 0.055 2
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0031325 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0031325 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0031325 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0031325 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0031325 Census, Compendium Yes 249 0.297 57 21 0.368 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0031325 Not Cancer Driver No 85 0.203 23 1 0.043 0
NUDT21 NUDT21 O43809 Cleavage and polyadenylation specificity factor subunit 5 chr16 GO:0031325 Not Cancer Driver No 21 0.093 37 3 0.081 0
NUP98_ENST00000359171 NUP98 P52948 Nuclear pore complex protein Nup98-Nup96 chr11 GO:0031325 Census Yes 227 0.125 1008 107 0.106 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0031325 Not Cancer Driver No 10 0.122 82 10 0.122 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0031325 Not Cancer Driver No 90 0.105 267 31 0.116 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0031325 Not Cancer Driver No 156 0.149 89 16 0.18 2
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0031325 Not Cancer Driver No 46 0.309 48 14 0.292 0
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0031325 Not Cancer Driver No 39 0.097 6 1 0.167 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0031325 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0031325 Not Cancer Driver No 58 0.101 470 51 0.109 6
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0031325 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0031325 Not Cancer Driver No 43 0.171 114 24 0.211 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0031325 Not Cancer Driver No 148 0.133 788 120 0.152 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0031325 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0031325 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0031325 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0031325 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0031325 Not Cancer Driver No 50 0.152 10 5 0.5 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0031325 Census, Compendium Yes 100 0.157 317 55 0.174 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0031325 Not Cancer Driver No 52 0.123 290 31 0.107 0
PAF1 PAF1 Q8N7H5 RNA polymerase II-associated factor 1 homolog chr19 GO:0031325 Not Cancer Driver No 77 0.145 378 56 0.148 0
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0031325 Census Yes 25 0.109 43 1 0.023 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0031325 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0031325 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0031325 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0031325 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAOX PAOX Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase chr10 GO:0031325 Not Cancer Driver No 70 0.137 29 0 0.0 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0031325 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0031325 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0031325 Not Cancer Driver No 71 0.111 197 22 0.112 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0031325 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP3_ENST00000431474 PARP3 Q9Y6F1 Protein mono-ADP-ribosyltransferase PARP3 chr3 GO:0031325 Not Cancer Driver No 70 0.131 269 38 0.141 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0031325 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0031325 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0031325 Census Yes 84 0.187 291 55 0.189 4
PAXBP1 PAXBP1 Q9Y5B6 PAX3- and PAX7-binding protein 1 chr21 GO:0031325 Not Cancer Driver No 96 0.105 532 55 0.103 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0031325 Not Cancer Driver No 120 0.112 461 39 0.085 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0031325 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0031325 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0031325 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0031325 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0031325 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0031325 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0031325 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0031325 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0031325 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0031325 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0031325 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0031325 Not Cancer Driver No 33 0.059 121 12 0.099 0
PEF1 PEF1 Q9UBV8 Peflin chr1 GO:0031325 Not Cancer Driver No 44 0.155 122 20 0.164 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0031325 Not Cancer Driver No 47 0.112 167 17 0.102 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0031325 Not Cancer Driver No 28 0.145 0 0 0.0 1
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0031325 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0031325 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0031325 Not Cancer Driver No 20 0.143 0 0 0.0 0
PHB2 PHB2 Q99623 Prohibitin-2 chr12 GO:0031325 Not Cancer Driver No 31 0.104 26 4 0.154 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0031325 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 GO:0031325 Not Cancer Driver No 62 0.109 277 29 0.105 0
PHF19_ENST00000373896 PHF19 Q5T6S3 PHD finger protein 19 chr9 GO:0031325 Not Cancer Driver No 66 0.114 129 19 0.147 0
PHF20 PHF20 Q9BVI0 PHD finger protein 20 chr20 GO:0031325 Not Cancer Driver No 130 0.128 667 82 0.123 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 GO:0031325 Not Cancer Driver No 45 0.112 331 37 0.112 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0031325 Not Cancer Driver No 154 0.145 603 93 0.154 1
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:0031325 Not Cancer Driver No 48 0.118 50 6 0.12 4
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 GO:0031325 Not Cancer Driver No 80 0.123 241 43 0.178 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0031325 Not Cancer Driver No 70 0.111 266 31 0.117 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0031325 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIBF1 PIBF1 Q8WXW3 Progesterone-induced-blocking factor 1 chr13 GO:0031325 Not Cancer Driver No 83 0.11 419 45 0.107 2
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0031325 Census Yes 89 0.137 320 42 0.131 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0031325 Not Cancer Driver No 50 0.12 49 3 0.061 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0031325 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0031325 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0031325 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0031325 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0031325 Not Cancer Driver No 193 0.142 315 45 0.143 0
PILRB PILRB Q9UKJ0 Paired immunoglobulin-like type 2 receptor beta chr7 GO:0031325 Not Cancer Driver No 29 0.128 26 3 0.115 0
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0031325 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0031325 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0031325 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0031325 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0031325 Not Cancer Driver No 138 0.142 232 38 0.164 0
PKD1 PKD1 P98161 Polycystin-1 chr16 GO:0031325 Not Cancer Driver No 393 0.091 690 66 0.096 92
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0031325 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0031325 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0031325 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0031325 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0031325 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0031325 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0031325 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0031325 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:0031325 Not Cancer Driver No 59 0.097 369 37 0.1 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 GO:0031325 Not Cancer Driver No 17 0.116 0 0 0.0 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0031325 Not Cancer Driver No 49 0.106 192 21 0.109 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0031325 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0031325 Not Cancer Driver No 75 0.116 202 15 0.074 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0031325 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0031325 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0031325 Not Cancer Driver No 53 0.102 177 23 0.13 4
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0031325 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0031325 Not Cancer Driver No 86 0.11 115 10 0.087 2
POGZ POGZ Q7Z3K3 Pogo transposable element with ZNF domain chr1 GO:0031325 Not Cancer Driver No 157 0.111 746 78 0.105 0
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0031325 Not Cancer Driver No 64 0.132 46 4 0.087 3
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0031325 Not Cancer Driver No 15 0.087 15 1 0.067 0
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 GO:0031325 Not Cancer Driver No 75 0.1 55 5 0.091 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 GO:0031325 Not Cancer Driver No 84 0.112 60 3 0.05 15
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0031325 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0031325 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0031325 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0031325 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0031325 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0031325 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0031325 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0031325 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0031325 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP1R12A_ENST00000261207 PPP1R12A O14974 Protein phosphatase 1 regulatory subunit 12A chr12 GO:0031325 Not Cancer Driver No 107 0.104 821 89 0.108 0
PPP1R14D_ENST00000299174 PPP1R14D Q9NXH3 Protein phosphatase 1 regulatory subunit 14D chr15 GO:0031325 Not Cancer Driver No 10 0.069 119 10 0.084 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0031325 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R15B PPP1R15B Q5SWA1 Protein phosphatase 1 regulatory subunit 15B chr1 GO:0031325 Not Cancer Driver No 72 0.101 415 45 0.108 1
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0031325 Not Cancer Driver No 132 0.233 220 66 0.3 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0031325 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0031325 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP1R7 PPP1R7 Q15435 Protein phosphatase 1 regulatory subunit 7 chr2 GO:0031325 Not Cancer Driver No 46 0.128 78 16 0.205 0
PPP2R5A PPP2R5A Q15172 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform chr1 GO:0031325 Not Cancer Driver No 55 0.113 93 5 0.054 0
PPP2R5D PPP2R5D Q14738 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform chr6 GO:0031325 Not Cancer Driver No 64 0.106 178 13 0.073 4
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0031325 Not Cancer Driver No 100 0.118 240 33 0.138 0
PRDM12 PRDM12 Q9H4Q4 PR domain zinc finger protein 12 chr9 GO:0031325 Not Cancer Driver No 26 0.071 82 1 0.012 6
PRDM7_ENST00000449207 PRDM7 Q9NQW5 Histone-lysine N-methyltransferase PRDM7 chr16 GO:0031325 Not Cancer Driver No 62 0.126 280 26 0.093 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0031325 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRDX6 PRDX6 P30041 Peroxiredoxin-6 chr1 GO:0031325 Not Cancer Driver No 46 0.205 13 4 0.308 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0031325 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRICKLE1_ENST00000640055 PRICKLE1 Q96MT3 Prickle-like protein 1 chr12 GO:0031325 Not Cancer Driver No 146 0.176 485 91 0.188 3
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0031325 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0031325 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0031325 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKAG2 PRKAG2 Q9UGJ0 5'-AMP-activated protein kinase subunit gamma-2 chr7 GO:0031325 Not Cancer Driver No 76 0.134 240 45 0.188 7
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0031325 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0031325 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0031325 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0031325 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0031325 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0031325 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0031325 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0031325 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0031325 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRL PRL P01236 Prolactin chr6 GO:0031325 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRLR PRLR P16471 Prolactin receptor chr5 GO:0031325 Not Cancer Driver No 154 0.248 282 70 0.248 2
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0031325 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRNP PRNP P04156 Major prion protein chr20 GO:0031325 Not Cancer Driver No 36 0.142 115 7 0.061 18
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0031325 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRPF19 PRPF19 Q9UMS4 Pre-mRNA-processing factor 19 chr11 GO:0031325 Not Cancer Driver No 71 0.141 109 16 0.147 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0031325 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0031325 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRRC1_ENST00000296666 PRRC1 Q96M27 Protein PRRC1 chr5 GO:0031325 Not Cancer Driver No 42 0.094 235 24 0.102 0
PRXL2C PRXL2C Q7RTV5 Peroxiredoxin-like 2C chr9 GO:0031325 Not Cancer Driver No 10 0.044 26 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0031325 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0031325 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0031325 Not Cancer Driver No 30 0.083 361 30 0.083 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0031325 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0031325 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0031325 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0031325 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0031325 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0031325 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 GO:0031325 Not Cancer Driver No 86 0.145 124 25 0.202 5
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0031325 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0031325 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0031325 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0031325 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0031325 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0031325 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0031325 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTTG1IP PTTG1IP P53801 Pituitary tumor-transforming gene 1 protein-interacting protein chr21 GO:0031325 Not Cancer Driver No 23 0.128 30 9 0.3 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 GO:0031325 Not Cancer Driver No 39 0.102 74 2 0.027 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0031325 Not Cancer Driver No 150 0.126 640 77 0.12 3
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0031325 Not Cancer Driver No 51 0.102 186 22 0.118 0
PXYLP1 PXYLP1 Q8TE99 2-phosphoxylose phosphatase 1 chr3 GO:0031325 Not Cancer Driver No 63 0.131 32 13 0.406 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0031325 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0031325 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB1B RAB1B Q9H0U4 Ras-related protein Rab-1B chr11 GO:0031325 Not Cancer Driver No 24 0.119 40 3 0.075 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0031325 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0031325 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 GO:0031325 Not Cancer Driver No 27 0.128 0 0 0.0 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0031325 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0031325 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0031325 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0031325 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0031325 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0031325 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0031325 Not Cancer Driver No 36 0.175 35 5 0.143 0
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0031325 Not Cancer Driver No 16 0.108 0 0 0.0 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0031325 Not Cancer Driver No 30 0.203 0 0 0.0 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0031325 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RAP2A RAP2A P10114 Ras-related protein Rap-2a chr13 GO:0031325 Not Cancer Driver No 15 0.082 9 0 0.0 0
RAP2B RAP2B P61225 Ras-related protein Rap-2b chr3 GO:0031325 Not Cancer Driver No 22 0.12 0 0 0.0 0
RAP2C_ENST00000370874 RAP2C Q9Y3L5 Ras-related protein Rap-2c chrX GO:0031325 Not Cancer Driver No 32 0.175 8 2 0.25 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0031325 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0031325 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASD2 RASD2 Q96D21 GTP-binding protein Rhes chr22 GO:0031325 Not Cancer Driver No 59 0.222 14 2 0.143 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0031325 Not Cancer Driver No 31 0.128 40 6 0.15 0
RASSF2 RASSF2 P50749 Ras association domain-containing protein 2 chr20 GO:0031325 Not Cancer Driver No 90 0.276 126 44 0.349 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 GO:0031325 Not Cancer Driver No 37 0.089 183 11 0.06 0
RBBP8_ENST00000327155 RBBP8 Q99708 DNA endonuclease RBBP8 chr18 GO:0031325 Not Cancer Driver No 99 0.11 750 76 0.101 1
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0031325 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBM20 RBM20 Q5T481 RNA-binding protein 20 chr10 GO:0031325 Not Cancer Driver No 55 0.045 957 41 0.043 10
RBM22 RBM22 Q9NW64 Pre-mRNA-splicing factor RBM22 chr5 GO:0031325 Not Cancer Driver No 51 0.121 214 29 0.136 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0031325 Not Cancer Driver No 29 0.123 20 3 0.15 0
RBM3_ENST00000376755 RBM3 P98179 RNA-binding protein 3 chrX GO:0031325 Not Cancer Driver No 22 0.14 134 18 0.134 0
RBMX RBMX P38159 RNA-binding motif protein, X chromosome chrX GO:0031325 Not Cancer Driver No 82 0.21 380 81 0.213 0
RBMXL1 RBMXL1 Q96E39 RNA binding motif protein, X-linked-like-1 chr1 GO:0031325 Not Cancer Driver No 77 0.197 371 75 0.202 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0031325 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0031325 Not Cancer Driver No 23 0.117 87 11 0.126 0
RBX1 RBX1 P62877 E3 ubiquitin-protein ligase RBX1 chr22 GO:0031325 Not Cancer Driver No 10 0.093 18 1 0.056 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0031325 Not Cancer Driver No 158 0.139 796 115 0.144 0
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0031325 Not Cancer Driver No 19 0.041 87 7 0.08 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0031325 Not Cancer Driver No 33 0.126 23 0 0.0 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0031325 Not Cancer Driver No 37 0.185 24 5 0.208 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0031325 Not Cancer Driver No 33 0.097 8 0 0.0 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0031325 Compendium Yes 75 0.136 400 48 0.12 0
RELN RELN P78509 Reelin chr7 GO:0031325 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0031325 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0031325 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0031325 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0031325 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0031325 Not Cancer Driver No 38 0.112 20 1 0.05 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0031325 Not Cancer Driver No 73 0.23 28 5 0.179 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0031325 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0031325 Not Cancer Driver No 63 0.14 105 13 0.124 0
RGN RGN Q15493 Regucalcin chrX GO:0031325 Not Cancer Driver No 38 0.127 14 3 0.214 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0031325 Not Cancer Driver No 38 0.121 69 9 0.13 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0031325 Not Cancer Driver No 20 0.146 3 0 0.0 0
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0031325 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RIOK1 RIOK1 Q9BRS2 Serine/threonine-protein kinase RIO1 chr6 GO:0031325 Not Cancer Driver No 69 0.121 301 37 0.123 0
RIOK2 RIOK2 Q9BVS4 Serine/threonine-protein kinase RIO2 chr5 GO:0031325 Not Cancer Driver No 68 0.123 253 33 0.13 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0031325 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0031325 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0031325 Not Cancer Driver No 66 0.127 295 39 0.132 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:0031325 Not Cancer Driver No 46 0.102 83 11 0.133 1
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0031325 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0031325 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 GO:0031325 Not Cancer Driver No 80 0.135 190 26 0.137 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0031325 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF20 RNF20 Q5VTR2 E3 ubiquitin-protein ligase BRE1A chr9 GO:0031325 Not Cancer Driver No 126 0.129 561 64 0.114 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0031325 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0031325 Not Cancer Driver No 132 0.132 645 80 0.124 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0031325 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0031325 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0031325 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0031325 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0031325 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROMO1_ENST00000397416 ROMO1 P60602 Reactive oxygen species modulator 1 chr20 GO:0031325 Not Cancer Driver No 9 0.114 0 0 0.0 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0031325 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 GO:0031325 Not Cancer Driver No 34 0.116 85 14 0.165 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0031325 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA4 RPS6KA4 O75676 Ribosomal protein S6 kinase alpha-4 chr11 GO:0031325 Not Cancer Driver No 72 0.093 220 11 0.05 0
RPS6KA5 RPS6KA5 O75582 Ribosomal protein S6 kinase alpha-5 chr14 GO:0031325 Not Cancer Driver No 97 0.121 187 18 0.096 0
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0031325 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0031325 Not Cancer Driver No 176 0.132 241 21 0.087 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0031325 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0031325 Not Cancer Driver No 54 0.143 97 15 0.155 0
RRP8 RRP8 O43159 Ribosomal RNA-processing protein 8 chr11 GO:0031325 Not Cancer Driver No 66 0.145 270 44 0.163 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0031325 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 GO:0031325 Not Cancer Driver No 83 0.117 568 67 0.118 0
RUFY4_ENST00000344321 RUFY4 Q6ZNE9 RUN and FYVE domain-containing protein 4 chr2 GO:0031325 Not Cancer Driver No 77 0.135 307 51 0.166 0
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0031325 Not Cancer Driver No 83 0.159 447 73 0.163 47
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0031325 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0031325 Not Cancer Driver No 62 0.134 100 13 0.13 0
RWDD3 RWDD3 Q9Y3V2 RWD domain-containing protein 3 chr1 GO:0031325 Not Cancer Driver No 40 0.15 12 4 0.333 0
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0031325 Not Cancer Driver No 11 0.113 3 1 0.333 0
S1PR2 S1PR2 O95136 Sphingosine 1-phosphate receptor 2 chr19 GO:0031325 Not Cancer Driver No 38 0.108 16 3 0.188 2
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:0031325 Not Cancer Driver No 39 0.113 90 6 0.067 0
SAP30BP SAP30BP Q9UHR5 SAP30-binding protein chr17 GO:0031325 Not Cancer Driver No 25 0.081 233 19 0.082 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0031325 Not Cancer Driver No 101 0.105 404 45 0.111 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0031325 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0031325 Not Cancer Driver No 53 0.096 6 1 0.167 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 GO:0031325 Not Cancer Driver No 13 0.082 82 8 0.098 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0031325 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 GO:0031325 Not Cancer Driver No 103 0.111 328 29 0.088 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0031325 Not Cancer Driver No 39 0.131 17 2 0.118 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0031325 Not Cancer Driver No 81 0.262 4 0 0.0 0
SELE SELE P16581 E-selectin chr1 GO:0031325 Not Cancer Driver No 137 0.225 12 0 0.0 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0031325 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0031325 Not Cancer Driver No 147 0.253 561 145 0.258 0
SENP2 SENP2 Q9HC62 Sentrin-specific protease 2 chr3 GO:0031325 Not Cancer Driver No 73 0.124 285 38 0.133 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0031325 Not Cancer Driver No 61 0.128 220 31 0.141 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0031325 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0031325 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0031325 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0031325 Not Cancer Driver No 62 0.091 154 12 0.078 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0031325 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:0031325 Census, Compendium Yes 244 0.187 477 80 0.168 0
SF3B4 SF3B4 Q15427 Splicing factor 3B subunit 4 chr1 GO:0031325 Not Cancer Driver No 69 0.163 273 56 0.205 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0031325 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0031325 Census Yes 81 0.234 68 22 0.324 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0031325 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0031325 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0031325 Not Cancer Driver No 110 0.128 440 72 0.164 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0031325 Not Cancer Driver No 86 0.109 526 52 0.099 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0031325 Not Cancer Driver No 41 0.112 82 10 0.122 0
SHLD1 SHLD1 Q8IYI0 Shieldin complex subunit 1 chr20 GO:0031325 Not Cancer Driver No 30 0.146 116 20 0.172 0
SHLD2_ENST00000298784 SHLD2 Q86V20 Shieldin complex subunit 2 chr10 GO:0031325 Not Cancer Driver No 84 0.101 157 14 0.089 0
SHLD3 SHLD3 Q6ZNX1 Shieldin complex subunit 3 chr5 GO:0031325 Not Cancer Driver No 3 0.012 81 1 0.012 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0031325 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0031325 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0031325 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0031325 Not Cancer Driver No 33 0.093 164 12 0.073 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0031325 Not Cancer Driver No 48 0.12 163 15 0.092 0
SKP1_ENST00000517625 SKP1 P63208 S-phase kinase-associated protein 1 chr5 GO:0031325 Not Cancer Driver No 19 0.117 95 17 0.179 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0031325 Not Cancer Driver No 52 0.123 52 6 0.115 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0031325 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0031325 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC25A37 SLC25A37 Q9NYZ2 Mitoferrin-1 chr8 GO:0031325 Not Cancer Driver No 45 0.133 68 5 0.074 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0031325 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0031325 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0031325 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0031325 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0031325 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC38A2 SLC38A2 Q96QD8 Sodium-coupled neutral amino acid transporter 2 chr12 GO:0031325 Not Cancer Driver No 60 0.119 9 1 0.111 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0031325 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0031325 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC39A5 SLC39A5 Q6ZMH5 Zinc transporter ZIP5 chr12 GO:0031325 Not Cancer Driver No 67 0.124 139 18 0.129 1
SLC45A3 SLC45A3 Q96JT2 Solute carrier family 45 member 3 chr1 GO:0031325 Census, Compendium Yes 75 0.136 25 6 0.24 0
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0031325 Not Cancer Driver No 193 0.179 281 60 0.214 8
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0031325 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 GO:0031325 Not Cancer Driver No 81 0.113 73 6 0.082 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0031325 Not Cancer Driver No 102 0.144 65 12 0.185 1
SLCO1C1_ENST00000266509 SLCO1C1 Q9NYB5 Solute carrier organic anion transporter family member 1C1 chr12 GO:0031325 Not Cancer Driver No 197 0.277 19 7 0.368 0
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0031325 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0031325 Not Cancer Driver No 112 0.095 725 76 0.105 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0031325 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0031325 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0031325 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0031325 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0031325 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0031325 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0031325 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0031325 Not Cancer Driver No 40 0.094 139 0 0.0 0
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0031325 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0031325 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0031325 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0031325 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMCHD1 SMCHD1 A6NHR9 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 chr18 GO:0031325 Not Cancer Driver No 240 0.12 342 45 0.132 45
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0031325 Not Cancer Driver No 107 0.114 357 38 0.106 0
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0031325 Not Cancer Driver No 82 0.184 216 52 0.241 0
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0031325 Not Cancer Driver No 93 0.147 51 4 0.078 111
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0031325 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0031325 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0031325 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0031325 Not Cancer Driver No 38 0.087 416 37 0.089 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0031325 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX18 SNX18 Q96RF0 Sorting nexin-18 chr5 GO:0031325 Not Cancer Driver No 54 0.086 236 7 0.03 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 GO:0031325 Not Cancer Driver No 36 0.082 98 4 0.041 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0031325 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0031325 Not Cancer Driver No 31 0.069 101 5 0.05 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0031325 Not Cancer Driver No 71 0.119 231 23 0.1 0
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:0031325 Not Cancer Driver No 73 0.133 49 4 0.082 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0031325 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0031325 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0031325 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0031325 Not Cancer Driver No 28 0.059 400 24 0.06 4
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0031325 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0031325 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0031325 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0031325 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0031325 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0031325 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0031325 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0031325 Not Cancer Driver No 78 0.103 414 48 0.116 0
SPIRE2 SPIRE2 Q8WWL2 Protein spire homolog 2 chr16 GO:0031325 Not Cancer Driver No 79 0.111 344 43 0.125 0
SPON1 SPON1 Q9HCB6 Spondin-1 chr11 GO:0031325 Not Cancer Driver No 120 0.149 191 30 0.157 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0031325 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0031325 Not Cancer Driver No 73 0.149 252 38 0.151 1
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0031325 Not Cancer Driver No 46 0.146 169 29 0.172 1
SPSB4 SPSB4 Q96A44 SPRY domain-containing SOCS box protein 4 chr3 GO:0031325 Not Cancer Driver No 42 0.154 75 3 0.04 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0031325 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:0031325 Not Cancer Driver No 72 0.128 9 2 0.222 5
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0031325 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0031325 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0031325 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0031325 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 GO:0031325 Not Cancer Driver No 50 0.184 189 40 0.212 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0031325 Not Cancer Driver No 27 0.182 0 0 0.0 6
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0031325 Not Cancer Driver No 330 0.315 820 282 0.344 0
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0031325 Not Cancer Driver No 17 0.215 0 0 0.0 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0031325 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAR STAR P49675 Steroidogenic acute regulatory protein, mitochondrial chr8 GO:0031325 Not Cancer Driver No 45 0.158 85 10 0.118 7
STARD4_ENST00000505803 STARD4 Q96DR4 StAR-related lipid transfer protein 4 chr5 GO:0031325 Not Cancer Driver No 48 0.234 0 0 0.0 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0031325 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT6_ENST00000543873 STAT6 P42226 Signal transducer and activator of transcription 6 chr12 GO:0031325 Census, Compendium Yes 106 0.125 325 44 0.135 0
STH STH Q8IWL8 Saitohin chr17 GO:0031325 Not Cancer Driver No 13 0.102 55 5 0.091 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0031325 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0031325 Not Cancer Driver No 70 0.144 231 30 0.13 0
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0031325 Not Cancer Driver No 40 0.112 117 9 0.077 0
STOX1_ENST00000399169 STOX1 Q6ZVD7 Storkhead-box protein 1 chr10 GO:0031325 Not Cancer Driver No 121 0.122 659 83 0.126 2
STPG4 STPG4 Q8N801 Protein STPG4 chr2 GO:0031325 Not Cancer Driver No 32 0.129 132 17 0.129 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0031325 Not Cancer Driver No 35 0.116 112 14 0.125 12
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:0031325 Not Cancer Driver No 165 0.152 572 87 0.152 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0031325 Not Cancer Driver No 72 0.092 140 12 0.086 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0031325 Not Cancer Driver No 59 0.143 15 1 0.067 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0031325 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0031325 Census Yes 96 0.151 131 27 0.206 5
SYMPK SYMPK Q92797 Symplekin chr19 GO:0031325 Not Cancer Driver No 156 0.122 398 42 0.106 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0031325 Not Cancer Driver No 93 0.149 285 39 0.137 0
TADA2B TADA2B Q86TJ2 Transcriptional adapter 2-beta chr4 GO:0031325 Not Cancer Driver No 55 0.131 128 19 0.148 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0031325 Census Yes 54 0.163 305 53 0.174 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0031325 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0031325 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0031325 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0031325 Not Cancer Driver No 123 0.137 494 64 0.13 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0031325 Not Cancer Driver No 51 0.123 202 15 0.074 27
TAZ_ENST00000612460 TAFAZZIN Q16635 Tafazzin chrX GO:0031325 Not Cancer Driver No 33 0.126 12 0 0.0 10
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0031325 Not Cancer Driver No 72 0.142 209 26 0.124 0
TBC1D5_ENST00000253692 TBC1D5 Q92609 TBC1 domain family member 5 chr3 GO:0031325 Not Cancer Driver No 117 0.147 358 58 0.162 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0031325 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0031325 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0031325 Not Cancer Driver No 70 0.131 348 50 0.144 0
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0031325 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0031325 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0031325 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCL1A TCL1A P56279 T-cell leukemia/lymphoma protein 1A chr14 GO:0031325 Census Yes 30 0.263 5 1 0.2 0
TCL1B TCL1B O95988 T-cell leukemia/lymphoma protein 1B chr14 GO:0031325 Not Cancer Driver No 38 0.297 11 1 0.091 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0031325 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0031325 Not Cancer Driver No 52 0.122 157 24 0.153 1
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0031325 Not Cancer Driver No 219 0.195 126 22 0.175 10
TENM1_ENST00000371130 TENM1 Q9UKZ4 Teneurin-1 chrX GO:0031325 Not Cancer Driver No 728 0.267 482 164 0.34 0
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0031325 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0031325 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0031325 Not Cancer Driver No 28 0.07 310 16 0.052 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0031325 Census Yes 110 0.097 212 16 0.075 31
TET1 TET1 Q8NFU7 Methylcytosine dioxygenase TET1 chr10 GO:0031325 Census, Compendium Yes 316 0.148 1551 234 0.151 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0031325 Compendium Yes 61 0.18 285 52 0.182 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0031325 Census Yes 89 0.117 80 6 0.075 1
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0031325 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0031325 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0031325 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0031325 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0031325 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0031325 Census, Compendium Yes 106 0.187 60 16 0.267 25
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0031325 Not Cancer Driver No 188 0.161 320 58 0.181 0
THRAP3_ENST00000469141 THRAP3 Q9Y2W1 Thyroid hormone receptor-associated protein 3 chr1 GO:0031325 Census Yes 137 0.143 955 137 0.143 0
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0031325 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0031325 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0031325 Not Cancer Driver No 154 0.127 367 51 0.139 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0031325 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0031325 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0031325 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0031325 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0031325 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0031325 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0031325 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0031325 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0031325 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP8L3 TNFAIP8L3 Q5GJ75 Tumor necrosis factor alpha-induced protein 8-like protein 3 chr15 GO:0031325 Not Cancer Driver No 40 0.137 111 12 0.108 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0031325 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0031325 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0031325 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0031325 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNFSF13 TNFSF13 O75888 Tumor necrosis factor ligand superfamily member 13 chr17 GO:0031325 Not Cancer Driver No 14 0.056 109 6 0.055 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0031325 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0031325 Not Cancer Driver No 28 0.153 1 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0031325 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0031325 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0031325 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0031325 Not Cancer Driver No 117 0.1 255 24 0.094 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0031325 Not Cancer Driver No 21 0.382 55 21 0.382 0
TNP2 TNP2 Q05952 Nuclear transition protein 2 chr16 GO:0031325 Not Cancer Driver No 23 0.167 138 23 0.167 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:0031325 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:0031325 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:0031325 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0031325 Not Cancer Driver No 35 0.101 214 18 0.084 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0031325 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOM1L1 TOM1L1 O75674 TOM1-like protein 1 chr17 GO:0031325 Not Cancer Driver No 51 0.107 268 29 0.108 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0031325 Not Cancer Driver No 149 0.143 795 105 0.132 0
TOX TOX O94900 Thymocyte selection-associated high mobility group box protein TOX chr8 GO:0031325 Not Cancer Driver No 112 0.213 494 108 0.219 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0031325 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0031325 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TRA2A TRA2A Q13595 Transformer-2 protein homolog alpha chr7 GO:0031325 Not Cancer Driver No 45 0.16 253 41 0.162 0
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0031325 Not Cancer Driver No 59 0.205 244 54 0.221 0
TRABD2A TRABD2A Q86V40 Metalloprotease TIKI1 chr2 GO:0031325 Not Cancer Driver No 80 0.158 132 35 0.265 0
TRABD2B TRABD2B A6NFA1 Metalloprotease TIKI2 chr1 GO:0031325 Not Cancer Driver No 3 0.006 211 1 0.005 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0031325 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0031325 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0031325 Not Cancer Driver No 67 0.128 62 7 0.113 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0031325 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0031325 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0031325 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0031325 Not Cancer Driver No 86 0.176 47 15 0.319 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0031325 Not Cancer Driver No 124 0.143 163 21 0.129 2
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0031325 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRMT112 TRMT112 Q9UI30 Multifunctional methyltransferase subunit TRM112-like protein chr11 GO:0031325 Not Cancer Driver No 15 0.12 17 2 0.118 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0031325 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0031325 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRRAP TRRAP Q9Y4A5 Transformation/transcription domain-associated protein chr7 GO:0031325 Census, Compendium Yes 554 0.144 402 59 0.147 8
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0031325 Not Cancer Driver No 37 0.112 73 7 0.096 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0031325 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSC2 TSC2 P49815 Tuberin chr16 GO:0031325 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0031325 Not Cancer Driver No 5 0.03 1 0 0.0 0
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 GO:0031325 Not Cancer Driver No 92 0.221 257 61 0.237 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0031325 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTC5 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0031325 Not Cancer Driver No 65 0.148 151 19 0.126 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0031325 Not Cancer Driver No 136 0.159 352 46 0.131 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0031325 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0031325 Not Cancer Driver No 159 0.106 659 74 0.112 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0031325 Not Cancer Driver No 23 0.114 132 11 0.083 7
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0031325 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXN TXN P10599 Thioredoxin chr9 GO:0031325 Not Cancer Driver No 6 0.057 0 0 0.0 0
TYROBP TYROBP O43914 TYRO protein tyrosine kinase-binding protein chr19 GO:0031325 Not Cancer Driver No 24 0.212 28 8 0.286 0
TYRP1 TYRP1 P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase chr9 GO:0031325 Not Cancer Driver No 81 0.151 87 13 0.149 2
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 GO:0031325 Compendium Yes 78 0.164 191 28 0.147 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:0031325 Not Cancer Driver No 84 0.131 219 33 0.151 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0031325 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0031325 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2C UBE2C O00762 Ubiquitin-conjugating enzyme E2 C chr20 GO:0031325 Not Cancer Driver No 13 0.073 40 0 0.0 0
UBE2D1 UBE2D1 P51668 Ubiquitin-conjugating enzyme E2 D1 chr10 GO:0031325 Not Cancer Driver No 13 0.088 14 0 0.0 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0031325 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0031325 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE2N UBE2N P61088 Ubiquitin-conjugating enzyme E2 N chr12 GO:0031325 Not Cancer Driver No 25 0.164 24 3 0.125 0
UBE2S UBE2S Q16763 Ubiquitin-conjugating enzyme E2 S chr19 GO:0031325 Not Cancer Driver No 25 0.113 102 12 0.118 0
UBE2V1_ENST00000371674 UBE2V1 Q13404 Ubiquitin-conjugating enzyme E2 variant 1 chr20 GO:0031325 Not Cancer Driver No 19 0.129 51 5 0.098 0
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0031325 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0031325 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0031325 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0031325 Not Cancer Driver No 82 0.131 581 79 0.136 8
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0031325 Not Cancer Driver No 100 0.131 567 77 0.136 1
UCN UCN P55089 Urocortin chr2 GO:0031325 Not Cancer Driver No 7 0.056 61 4 0.066 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0031325 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0031325 Not Cancer Driver No 20 0.083 89 4 0.045 1
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0031325 Not Cancer Driver No 146 0.129 329 36 0.109 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0031325 Not Cancer Driver No 10 0.079 41 1 0.024 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0031325 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0031325 Not Cancer Driver No 30 0.087 326 29 0.089 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0031325 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0031325 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0031325 Not Cancer Driver No 170 0.154 215 45 0.209 0
USP9X_ENST00000378308 USP9X Q93008 Probable ubiquitin carboxyl-terminal hydrolase FAF-X chrX GO:0031325 Census, Compendium Yes 339 0.133 405 51 0.126 1
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:0031325 Not Cancer Driver No 49 0.095 39 4 0.103 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0031325 Not Cancer Driver No 89 0.127 243 28 0.115 0
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0031325 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAV2 VAV2 P52735 Guanine nucleotide exchange factor VAV2 chr9 GO:0031325 Not Cancer Driver No 127 0.145 135 17 0.126 0
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0031325 Not Cancer Driver No 153 0.181 102 18 0.176 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0031325 Not Cancer Driver No 88 0.109 186 16 0.086 16
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0031325 Not Cancer Driver No 38 0.134 36 4 0.111 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0031325 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0031325 Not Cancer Driver No 128 0.305 37 12 0.324 0
VPS13D VPS13D Q5THJ4 Intermembrane lipid transfer protein VPS13D chr1 GO:0031325 Not Cancer Driver No 501 0.114 973 118 0.121 8
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0031325 Not Cancer Driver No 68 0.085 99 9 0.091 1
VPS72 VPS72 Q15906 Vacuolar protein sorting-associated protein 72 homolog chr1 GO:0031325 Not Cancer Driver No 43 0.118 329 37 0.112 0
VRK3_ENST00000594948 VRK3 Q8IV63 Inactive serine/threonine-protein kinase VRK3 chr19 GO:0031325 Not Cancer Driver No 65 0.137 180 18 0.1 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0031325 Not Cancer Driver No 106 0.164 571 95 0.166 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0031325 Census, Compendium Yes 75 0.149 400 55 0.138 30
WBP1L_ENST00000369889 WBP1L Q9NX94 WW domain binding protein 1-like chr10 GO:0031325 Not Cancer Driver No 27 0.079 225 21 0.093 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0031325 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:0031325 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR45_ENST00000634944 WDR45 Q9Y484 WD repeat domain phosphoinositide-interacting protein 4 chrX GO:0031325 Compendium Yes 62 0.172 10 1 0.1 0
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0031325 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:0031325 Not Cancer Driver No 30 0.09 35 3 0.086 0
WDR61 WDR61 Q9GZS3 WD repeat-containing protein 61 chr15 GO:0031325 Not Cancer Driver No 25 0.082 7 1 0.143 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:0031325 Not Cancer Driver No 67 0.081 87 7 0.08 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0031325 Not Cancer Driver No 105 0.118 203 10 0.049 39
WIPI1 WIPI1 Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 chr17 GO:0031325 Not Cancer Driver No 45 0.101 113 9 0.08 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0031325 Not Cancer Driver No 281 0.156 1281 200 0.156 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0031325 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0031325 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0031325 Not Cancer Driver No 66 0.174 0 0 0.0 2
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0031325 Not Cancer Driver No 66 0.12 232 29 0.125 4
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0031325 Census, Compendium Yes 164 0.115 373 41 0.11 2
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0031325 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0031325 Not Cancer Driver No 279 0.209 134 24 0.179 1
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0031325 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0031325 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0031325 Not Cancer Driver No 87 0.119 118 11 0.093 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0031325 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0031325 Not Cancer Driver No 49 0.132 359 47 0.131 0
YEATS4 YEATS4 O95619 YEATS domain-containing protein 4 chr12 GO:0031325 Not Cancer Driver No 23 0.101 17 1 0.059 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0031325 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0031325 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0031325 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0031325 Compendium Yes 151 0.204 433 80 0.185 4
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0031325 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0031325 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0031325 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 GO:0031325 Not Cancer Driver No 139 0.146 929 134 0.144 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0031325 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 GO:0031325 Not Cancer Driver No 142 0.157 344 63 0.183 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:0031325 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZCWPW1 ZCWPW1 Q9H0M4 Zinc finger CW-type PWWP domain protein 1 chr7 GO:0031325 Not Cancer Driver No 90 0.139 456 61 0.134 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0031325 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0031325 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0031325 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0031325 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZFP91 ZFP91 Q96JP5 E3 ubiquitin-protein ligase ZFP91 chr11 GO:0031325 Not Cancer Driver No 85 0.149 383 55 0.144 0
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0031325 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZNF205_ENST00000382192 ZNF205 O95201 Zinc finger protein 205 chr16 GO:0031325 Not Cancer Driver No 74 0.134 367 49 0.134 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0031325 Not Cancer Driver No 126 0.191 54 12 0.222 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0031325 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZSWIM8_ENST00000605216 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 GO:0031325 Not Cancer Driver No 204 0.111 877 103 0.117 0