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Total number of protein in "GO:0031267" GO term:  266

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0031267 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0031267 Not Cancer Driver No 56 0.109 361 38 0.105 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0031267 Not Cancer Driver No 127 0.271 0 0 0.0 0
AFDN_ENST00000447894 AFDN P55196 Afadin chr6 GO:0031267 Census Yes 248 0.136 1247 180 0.144 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0031267 Not Cancer Driver No 359 0.128 2091 258 0.123 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0031267 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANKFY1_ENST00000341657 ANKFY1 Q9P2R3 Rabankyrin-5 chr17 GO:0031267 Not Cancer Driver No 109 0.093 185 29 0.157 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0031267 Not Cancer Driver No 145 0.138 239 33 0.138 0
AP1G1_ENST00000569748 AP1G1 O43747 AP-1 complex subunit gamma-1 chr16 GO:0031267 Not Cancer Driver No 111 0.135 144 22 0.153 0
AP3M1 AP3M1 Q9Y2T2 AP-3 complex subunit mu-1 chr10 GO:0031267 Not Cancer Driver No 45 0.108 19 1 0.053 0
ARFIP2_ENST00000254584 ARFIP2 P53365 Arfaptin-2 chr11 GO:0031267 Not Cancer Driver No 37 0.109 144 15 0.104 0
ARHGAP1 ARHGAP1 Q07960 Rho GTPase-activating protein 1 chr11 GO:0031267 Not Cancer Driver No 39 0.089 90 8 0.089 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:0031267 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0031267 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGEF16 ARHGEF16 Q5VV41 Rho guanine nucleotide exchange factor 16 chr1 GO:0031267 Not Cancer Driver No 68 0.096 297 13 0.044 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0031267 Not Cancer Driver No 146 0.148 450 70 0.156 0
ATP6AP1 ATP6AP1 Q15904 V-type proton ATPase subunit S1 chrX GO:0031267 Not Cancer Driver No 67 0.143 0 0 0.0 4
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0031267 Not Cancer Driver No 228 0.152 171 46 0.269 52
BICD1 BICD1 Q96G01 Protein bicaudal D homolog 1 chr12 GO:0031267 Not Cancer Driver No 124 0.127 656 86 0.131 0
BICD2_ENST00000375512 BICD2 Q8TD16 Protein bicaudal D homolog 2 chr9 GO:0031267 Not Cancer Driver No 115 0.14 546 73 0.134 10
BICDL1 BICDL1 Q6ZP65 BICD family-like cargo adapter 1 chr12 GO:0031267 Not Cancer Driver No 62 0.108 380 45 0.118 0
BICDL2 BICDL2 A1A5D9 BICD family-like cargo adapter 2 chr16 GO:0031267 Not Cancer Driver No 50 0.098 446 49 0.11 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0031267 Not Cancer Driver No 20 0.141 49 6 0.122 0
BRAF BRAF P15056 Serine/threonine-protein kinase B-raf chr7 GO:0031267 Census, Compendium Yes 791 1.033 310 43 0.139 39
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 GO:0031267 Not Cancer Driver No 7 0.093 14 1 0.071 0
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:0031267 Not Cancer Driver No 64 0.133 11 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0031267 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCDC186 CCDC186 Q7Z3E2 Coiled-coil domain-containing protein 186 chr10 GO:0031267 Not Cancer Driver No 99 0.11 702 80 0.114 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 GO:0031267 Not Cancer Driver No 185 0.108 696 92 0.132 0
CDC42EP2 CDC42EP2 O14613 Cdc42 effector protein 2 chr11 GO:0031267 Not Cancer Driver No 19 0.09 162 17 0.105 0
CDC42EP4 CDC42EP4 Q9H3Q1 Cdc42 effector protein 4 chr17 GO:0031267 Not Cancer Driver No 47 0.132 352 47 0.134 0
CDC42EP5 CDC42EP5 Q6NZY7 Cdc42 effector protein 5 chr19 GO:0031267 Not Cancer Driver No 4 0.027 147 4 0.027 0
CDC42SE1_ENST00000540998 CDC42SE1 Q9NRR8 CDC42 small effector protein 1 chr1 GO:0031267 Not Cancer Driver No 10 0.127 70 10 0.143 0
CDC42SE2 CDC42SE2 Q9NRR3 CDC42 small effector protein 2 chr5 GO:0031267 Not Cancer Driver No 1 0.012 57 1 0.018 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0031267 Not Cancer Driver No 165 0.172 685 120 0.175 18
CHM CHM P24386 Rab proteins geranylgeranyltransferase component A 1 chrX GO:0031267 Not Cancer Driver No 113 0.173 179 40 0.223 3
CHML CHML P26374 Rab proteins geranylgeranyltransferase component A 2 chr1 GO:0031267 Not Cancer Driver No 91 0.139 197 25 0.127 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0031267 Not Cancer Driver No 24 0.126 6 1 0.167 0
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0031267 Not Cancer Driver No 61 0.129 84 13 0.155 0
CSE1L CSE1L P55060 Exportin-2 chr20 GO:0031267 Not Cancer Driver No 109 0.112 32 5 0.156 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0031267 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0031267 Not Cancer Driver No 211 0.165 86 11 0.128 3
DAAM1 DAAM1 Q9Y4D1 Disheveled-associated activator of morphogenesis 1 chr14 GO:0031267 Not Cancer Driver No 152 0.141 391 47 0.12 0
DAAM2 DAAM2 Q86T65 Disheveled-associated activator of morphogenesis 2 chr6 GO:0031267 Not Cancer Driver No 183 0.171 272 55 0.202 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0031267 Not Cancer Driver No 56 0.123 82 7 0.085 0
DENND1B DENND1B Q6P3S1 DENN domain-containing protein 1B chr1 GO:0031267 Not Cancer Driver No 69 0.089 299 19 0.064 0
DENND5A DENND5A Q6IQ26 DENN domain-containing protein 5A chr11 GO:0031267 Not Cancer Driver No 134 0.104 231 21 0.091 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0031267 Not Cancer Driver No 118 0.093 692 57 0.082 1
DIAPH2 DIAPH2 O60879 Protein diaphanous homolog 2 chrX GO:0031267 Not Cancer Driver No 195 0.177 460 95 0.207 0
DIAPH3 DIAPH3 Q9NSV4 Protein diaphanous homolog 3 chr13 GO:0031267 Not Cancer Driver No 189 0.158 492 78 0.159 0
DMXL2_ENST00000251076 DMXL2 Q8TDJ6 DmX-like protein 2 chr15 GO:0031267 Not Cancer Driver No 428 0.141 738 102 0.138 2
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0031267 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOCK11 DOCK11 Q5JSL3 Dedicator of cytokinesis protein 11 chrX GO:0031267 Not Cancer Driver No 312 0.151 240 29 0.121 0
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0031267 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK2 DOCK2 Q92608 Dedicator of cytokinesis protein 2 chr5 GO:0031267 Not Cancer Driver No 480 0.262 266 79 0.297 2
DOCK3 DOCK3 Q8IZD9 Dedicator of cytokinesis protein 3 chr3 GO:0031267 Not Cancer Driver No 365 0.18 458 69 0.151 0
DOCK4 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 GO:0031267 Not Cancer Driver No 331 0.168 397 80 0.202 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0031267 Not Cancer Driver No 278 0.149 330 45 0.136 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0031267 Not Cancer Driver No 262 0.122 454 53 0.117 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0031267 Not Cancer Driver No 73 0.105 434 38 0.088 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0031267 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0031267 Not Cancer Driver No 97 0.135 437 58 0.133 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0031267 Not Cancer Driver No 104 0.114 284 33 0.116 0
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0031267 Not Cancer Driver No 72 0.135 90 12 0.133 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0031267 Not Cancer Driver No 106 0.129 459 54 0.118 0
ERC1 ERC1 Q8IUD2 ELKS/Rab6-interacting/CAST family member 1 chr12 GO:0031267 Census Yes 127 0.114 1013 119 0.117 0
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0031267 Not Cancer Driver No 55 0.119 297 37 0.125 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0031267 Not Cancer Driver No 70 0.088 381 27 0.071 0
EVI5_ENST00000370331 EVI5 O60447 Ecotropic viral integration site 5 protein homolog chr1 GO:0031267 Not Cancer Driver No 115 0.142 416 61 0.147 0
EXOC2 EXOC2 Q96KP1 Exocyst complex component 2 chr6 GO:0031267 Not Cancer Driver No 105 0.114 134 18 0.134 0
EXOC4 EXOC4 Q96A65 Exocyst complex component 4 chr7 GO:0031267 Not Cancer Driver No 164 0.168 133 33 0.248 0
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 GO:0031267 Not Cancer Driver No 59 0.083 57 4 0.07 0
EXOC8 EXOC8 Q8IYI6 Exocyst complex component 8 chr1 GO:0031267 Not Cancer Driver No 84 0.116 195 21 0.108 0
EXPH5 EXPH5 Q8NEV8 Exophilin-5 chr11 GO:0031267 Not Cancer Driver No 290 0.146 1739 256 0.147 0
FAM45A DENND10 Q8TCE6 DENN domain-containing protein 10 chr10 GO:0031267 Not Cancer Driver No 33 0.092 13 1 0.077 0
FAM49A_ENST00000406434 CYRIA Q9H0Q0 CYFIP-related Rac1 interactor A chr2 GO:0031267 Not Cancer Driver No 74 0.229 36 3 0.083 0
FAM49B_ENST00000519540 CYRIB Q9NUQ9 CYFIP-related Rac1 interactor B chr8 GO:0031267 Not Cancer Driver No 53 0.164 78 11 0.141 0
FARP1_ENST00000319562 FARP1 Q9Y4F1 FERM, ARHGEF and pleckstrin domain-containing protein 1 chr13 GO:0031267 Not Cancer Driver No 147 0.141 315 60 0.19 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0031267 Not Cancer Driver No 114 0.139 145 21 0.145 0
FGD1 FGD1 P98174 FYVE, RhoGEF and PH domain-containing protein 1 chrX GO:0031267 Not Cancer Driver No 139 0.145 520 74 0.142 5
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0031267 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGD3 FGD3 Q5JSP0 FYVE, RhoGEF and PH domain-containing protein 3 chr9 GO:0031267 Not Cancer Driver No 117 0.161 404 72 0.178 0
FGD4_ENST00000427716 FGD4 Q96M96 FYVE, RhoGEF and PH domain-containing protein 4 chr12 GO:0031267 Not Cancer Driver No 78 0.102 290 28 0.097 2
FGD5 FGD5 Q6ZNL6 FYVE, RhoGEF and PH domain-containing protein 5 chr3 GO:0031267 Compendium Yes 275 0.188 915 180 0.197 0
FGD6 FGD6 Q6ZV73 FYVE, RhoGEF and PH domain-containing protein 6 chr12 GO:0031267 Not Cancer Driver No 198 0.138 804 117 0.146 0
FLNA FLNA P21333 Filamin-A chrX GO:0031267 Census Yes 416 0.157 1456 214 0.147 28
FMNL1 FMNL1 O95466 Formin-like protein 1 chr17 GO:0031267 Not Cancer Driver No 115 0.105 524 32 0.061 0
FMNL2 FMNL2 Q96PY5 Formin-like protein 2 chr2 GO:0031267 Not Cancer Driver No 119 0.11 409 56 0.137 0
FMNL3_ENST00000550488 FMNL3 Q8IVF7 Formin-like protein 3 chr12 GO:0031267 Not Cancer Driver No 140 0.136 284 37 0.13 0
GAPVD1_ENST00000495955 GAPVD1 Q14C86 GTPase-activating protein and VPS9 domain-containing protein 1 chr9 GO:0031267 Not Cancer Driver No 188 0.127 705 93 0.132 0
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 GO:0031267 Not Cancer Driver No 54 0.113 232 29 0.125 1
GCC1 GCC1 Q96CN9 GRIP and coiled-coil domain-containing protein 1 chr7 GO:0031267 Not Cancer Driver No 118 0.152 508 69 0.136 0
GCC2 GCC2 Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 chr2 GO:0031267 Not Cancer Driver No 178 0.106 999 113 0.113 0
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0031267 Not Cancer Driver No 69 0.154 34 6 0.176 2
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 GO:0031267 Not Cancer Driver No 49 0.11 23 2 0.087 0
GGA1 GGA1 Q9UJY5 ADP-ribosylation factor-binding protein GGA1 chr22 GO:0031267 Not Cancer Driver No 75 0.117 385 33 0.086 0
GGA2 GGA2 Q9UJY4 ADP-ribosylation factor-binding protein GGA2 chr16 GO:0031267 Not Cancer Driver No 84 0.137 240 37 0.154 0
GGA3 GGA3 Q9NZ52 ADP-ribosylation factor-binding protein GGA3 chr17 GO:0031267 Not Cancer Driver No 73 0.101 419 41 0.098 0
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0031267 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GOLGA5 GOLGA5 Q8TBA6 Golgin subfamily A member 5 chr14 GO:0031267 Census Yes 89 0.122 591 62 0.105 0
GRASP TAMALIN Q7Z6J2 Protein TAMALIN chr12 GO:0031267 Not Cancer Driver No 24 0.061 234 14 0.06 0
HACE1 HACE1 Q8IYU2 E3 ubiquitin-protein ligase HACE1 chr6 GO:0031267 Not Cancer Driver No 126 0.139 103 12 0.117 0
HPS4_ENST00000336873 HPS4 Q9NQG7 Hermansky-Pudlak syndrome 4 protein chr22 GO:0031267 Not Cancer Driver No 96 0.136 343 57 0.166 0
HPS6 HPS6 Q86YV9 Hermansky-Pudlak syndrome 6 protein chr10 GO:0031267 Not Cancer Driver No 77 0.099 145 20 0.138 0
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 GO:0031267 Not Cancer Driver No 11 0.083 0 0 0.0 0
INF2 INF2 Q27J81 Inverted formin-2 chr14 GO:0031267 Not Cancer Driver No 120 0.096 635 49 0.077 30
IPO11_ENST00000325324 IPO11 Q9UI26 Importin-11 chr5 GO:0031267 Not Cancer Driver No 82 0.084 66 4 0.061 0
IPO13 IPO13 O94829 Importin-13 chr1 GO:0031267 Not Cancer Driver No 98 0.102 42 7 0.167 0
IPO4 IPO4 Q8TEX9 Importin-4 chr14 GO:0031267 Not Cancer Driver No 106 0.098 87 5 0.057 0
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0031267 Not Cancer Driver No 128 0.117 52 3 0.058 0
IPO7 IPO7 O95373 Importin-7 chr11 GO:0031267 Not Cancer Driver No 138 0.133 202 30 0.149 0
IPO8 IPO8 O15397 Importin-8 chr12 GO:0031267 Not Cancer Driver No 130 0.125 111 13 0.117 0
IPO9 IPO9 Q96P70 Importin-9 chr1 GO:0031267 Not Cancer Driver No 145 0.139 102 22 0.216 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0031267 Not Cancer Driver No 183 0.11 351 35 0.1 0
IQGAP2 IQGAP2 Q13576 Ras GTPase-activating-like protein IQGAP2 chr5 GO:0031267 Not Cancer Driver No 237 0.15 255 50 0.196 0
IQGAP3 IQGAP3 Q86VI3 Ras GTPase-activating-like protein IQGAP3 chr1 GO:0031267 Not Cancer Driver No 233 0.143 257 36 0.14 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0031267 Not Cancer Driver No 28 0.061 216 7 0.032 0
KCTD13 KCTD13 Q8WZ19 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 chr16 GO:0031267 Not Cancer Driver No 33 0.1 95 10 0.105 0
KIAA0355 GARRE1 O15063 Granule associated Rac and RHOG effector protein 1 chr19 GO:0031267 Not Cancer Driver No 115 0.107 614 66 0.107 0
KIF3A_ENST00000378746 KIF3A Q9Y496 Kinesin-like protein KIF3A chr5 GO:0031267 Not Cancer Driver No 92 0.132 409 59 0.144 0
KIF3B KIF3B O15066 Kinesin-like protein KIF3B chr20 GO:0031267 Not Cancer Driver No 105 0.141 485 69 0.142 2
KNTC1 KNTC1 P50748 Kinetochore-associated protein 1 chr12 GO:0031267 Not Cancer Driver No 250 0.113 70 9 0.129 0
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 GO:0031267 Not Cancer Driver No 92 0.105 94 11 0.117 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0031267 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSM2 LSM2 Q9Y333 U6 snRNA-associated Sm-like protein LSm2 chr6 GO:0031267 Not Cancer Driver No 10 0.105 3 0 0.0 0
LZTR1_ENST00000646124 LZTR1 Q8N653 Leucine-zipper-like transcriptional regulator 1 chr22 GO:0031267 Census, Compendium Yes 160 0.19 106 18 0.17 26
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0031267 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAPKAP1 MAPKAP1 Q9BPZ7 Target of rapamycin complex 2 subunit MAPKAP1 chr9 GO:0031267 Not Cancer Driver No 70 0.134 173 25 0.145 0
MICAL1_ENST00000358807 MICAL1 Q8TDZ2 [F-actin]-monooxygenase MICAL1 chr6 GO:0031267 Not Cancer Driver No 112 0.105 364 37 0.102 0
MICAL3 MICAL3 Q7RTP6 [F-actin]-monooxygenase MICAL3 chr22 GO:0031267 Not Cancer Driver No 248 0.124 1264 159 0.126 0
MICALL1 MICALL1 Q8N3F8 MICAL-like protein 1 chr22 GO:0031267 Not Cancer Driver No 90 0.104 630 72 0.114 0
MICALL2 MICALL2 Q8IY33 MICAL-like protein 2 chr7 GO:0031267 Not Cancer Driver No 110 0.122 675 88 0.13 0
MLPH MLPH Q9BV36 Melanophilin chr2 GO:0031267 Not Cancer Driver No 78 0.13 463 57 0.123 1
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0031267 Not Cancer Driver No 62 0.083 582 49 0.084 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0031267 Not Cancer Driver No 608 0.13 1398 189 0.135 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0031267 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYO5A MYO5A Q9Y4I1 Unconventional myosin-Va chr15 GO:0031267 Census, Compendium Yes 224 0.121 497 58 0.117 0
MYO5B MYO5B Q9ULV0 Unconventional myosin-Vb chr18 GO:0031267 Not Cancer Driver No 269 0.146 505 68 0.135 14
MYO9B_ENST00000594824 MYO9B Q13459 Unconventional myosin-IXb chr19 GO:0031267 Not Cancer Driver No 226 0.105 827 80 0.097 0
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0031267 Not Cancer Driver No 133 0.155 599 95 0.159 0
NCF2 NCF2 P19878 Neutrophil cytosol factor 2 chr1 GO:0031267 Not Cancer Driver No 97 0.184 183 34 0.186 14
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0031267 Not Cancer Driver No 129 0.114 44 3 0.068 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0031267 Census Yes 66 0.168 140 22 0.157 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0031267 Not Cancer Driver No 57 0.133 172 25 0.145 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0031267 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:0031267 Not Cancer Driver No 27 0.057 215 14 0.065 0
NPC1L1 NPC1L1 Q9UHC9 NPC1-like intracellular cholesterol transporter 1 chr7 GO:0031267 Not Cancer Driver No 222 0.163 8 2 0.25 0
NUTF2_ENST00000569436 NUTF2 P61970 Nuclear transport factor 2 chr16 GO:0031267 Not Cancer Driver No 24 0.189 6 4 0.667 0
NXT1 NXT1 Q9UKK6 NTF2-related export protein 1 chr20 GO:0031267 Not Cancer Driver No 16 0.114 0 0 0.0 0
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0031267 Not Cancer Driver No 151 0.168 126 24 0.19 41
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0031267 Not Cancer Driver No 58 0.101 470 51 0.109 6
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0031267 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0031267 Compendium Yes 89 0.17 242 49 0.202 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0031267 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:0031267 Not Cancer Driver No 25 0.072 177 13 0.073 0
PDE6D PDE6D O43924 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta chr2 GO:0031267 Not Cancer Driver No 23 0.153 1 0 0.0 0
PEX5L PEX5L Q8IYB4 PEX5-related protein chr3 GO:0031267 Not Cancer Driver No 152 0.243 346 103 0.298 0
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0031267 Not Cancer Driver No 73 0.114 321 36 0.112 2
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0031267 Not Cancer Driver No 16 0.114 7 1 0.143 3
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0031267 Census Yes 89 0.137 320 42 0.131 0
PIFO PIFO Q8TCI5 Protein pitchfork chr1 GO:0031267 Not Cancer Driver No 31 0.162 70 11 0.157 0
PIH1D2 PIH1D2 Q8WWB5 PIH1 domain-containing protein 2 chr11 GO:0031267 Not Cancer Driver No 33 0.105 55 5 0.091 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0031267 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 GO:0031267 Not Cancer Driver No 123 0.125 415 48 0.116 0
PKN3 PKN3 Q6P5Z2 Serine/threonine-protein kinase N3 chr9 GO:0031267 Not Cancer Driver No 99 0.111 392 49 0.125 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0031267 Not Cancer Driver No 367 0.159 780 107 0.137 1
PPP6R1_ENST00000587283 PPP6R1 Q9UPN7 Serine/threonine-protein phosphatase 6 regulatory subunit 1 chr19 GO:0031267 Not Cancer Driver No 82 0.093 471 47 0.1 0
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 GO:0031267 Not Cancer Driver No 145 0.113 1118 133 0.119 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0031267 Not Cancer Driver No 66 0.129 356 43 0.121 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 GO:0031267 Not Cancer Driver No 51 0.067 605 33 0.055 0
RAB11FIP4 RAB11FIP4 Q86YS3 Rab11 family-interacting protein 4 chr17 GO:0031267 Not Cancer Driver No 76 0.119 434 54 0.124 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0031267 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0031267 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0031267 Not Cancer Driver No 41 0.158 1 0 0.0 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0031267 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0031267 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0031267 Not Cancer Driver No 27 0.13 11 0 0.0 4
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0031267 Not Cancer Driver No 37 0.179 26 3 0.115 0
RABGAP1 RABGAP1 Q9Y3P9 Rab GTPase-activating protein 1 chr9 GO:0031267 Not Cancer Driver No 114 0.107 407 40 0.098 0
RABGAP1L RABGAP1L Q5R372 Rab GTPase-activating protein 1-like chr1 GO:0031267 Not Cancer Driver No 116 0.142 235 33 0.14 0
RABGEF1_ENST00000284957 RABGEF1 Q9UJ41 Rab5 GDP/GTP exchange factor chr7 GO:0031267 Not Cancer Driver No 73 0.149 175 35 0.2 0
RABGGTA RABGGTA Q92696 Geranylgeranyl transferase type-2 subunit alpha chr14 GO:0031267 Not Cancer Driver No 74 0.131 37 2 0.054 0
RABGGTB RABGGTB P53611 Geranylgeranyl transferase type-2 subunit beta chr1 GO:0031267 Not Cancer Driver No 50 0.151 4 1 0.25 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0031267 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0031267 Not Cancer Driver No 65 0.099 381 46 0.121 0
RANBP17 RANBP17 Q9H2T7 Ran-binding protein 17 chr5 GO:0031267 Not Cancer Driver No 147 0.135 14 2 0.143 0
RANBP1_ENST00000331821 RANBP1 P43487 Ran-specific GTPase-activating protein chr22 GO:0031267 Not Cancer Driver No 19 0.095 137 16 0.117 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0031267 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0031267 Not Cancer Driver No 73 0.1 413 30 0.073 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0031267 Not Cancer Driver No 65 0.111 159 17 0.107 0
RANGRF RANGRF Q9HD47 Ran guanine nucleotide release factor chr17 GO:0031267 Not Cancer Driver No 10 0.054 42 5 0.119 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0031267 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0031267 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF4 RAPGEF4 Q8WZA2 Rap guanine nucleotide exchange factor 4 chr2 GO:0031267 Not Cancer Driver No 149 0.147 191 29 0.152 0
RAPGEF6_ENST00000509018 RAPGEF6 Q8TEU7 Rap guanine nucleotide exchange factor 6 chr5 GO:0031267 Not Cancer Driver No 192 0.12 789 92 0.117 0
RASGRP3_ENST00000402538 RASGRP3 Q8IV61 Ras guanyl-releasing protein 3 chr2 GO:0031267 Not Cancer Driver No 119 0.172 145 20 0.138 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 GO:0031267 Not Cancer Driver No 37 0.089 183 11 0.06 0
RBSN RBSN Q9H1K0 Rabenosyn-5 chr3 GO:0031267 Not Cancer Driver No 118 0.151 533 85 0.159 0
RCC1_ENST00000373833 RCC1 P18754 Regulator of chromosome condensation chr1 GO:0031267 Not Cancer Driver No 54 0.128 143 15 0.105 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0031267 Not Cancer Driver No 63 0.121 194 27 0.139 0
RGP1 RGP1 Q92546 RAB6A-GEF complex partner protein 2 chr9 GO:0031267 Not Cancer Driver No 44 0.113 120 13 0.108 0
RGPD8 RGPD8 O14715 RANBP2-like and GRIP domain-containing protein 8 chr2 GO:0031267 Not Cancer Driver No 129 0.073 621 71 0.114 0
RHOBTB3 RHOBTB3 O94955 Rho-related BTB domain-containing protein 3 chr5 GO:0031267 Not Cancer Driver No 67 0.11 34 2 0.059 0
RHOH_ENST00000617441 RHOH Q15669 Rho-related GTP-binding protein RhoH chr4 GO:0031267 Census Yes 41 0.215 12 3 0.25 0
RIC1 RIC1 Q4ADV7 Guanine nucleotide exchange factor subunit RIC1 chr9 GO:0031267 Not Cancer Driver No 159 0.112 252 15 0.06 1
RILP RILP Q96NA2 Rab-interacting lysosomal protein chr17 GO:0031267 Not Cancer Driver No 30 0.075 333 21 0.063 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0031267 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIMS3 RIMS3 Q9UJD0 Regulating synaptic membrane exocytosis protein 3 chr1 GO:0031267 Not Cancer Driver No 61 0.198 162 39 0.241 0
RIMS4_ENST00000372851 RIMS4 Q9H426 Regulating synaptic membrane exocytosis protein 4 chr20 GO:0031267 Not Cancer Driver No 63 0.234 71 13 0.183 0
RIN1 RIN1 Q13671 Ras and Rab interactor 1 chr11 GO:0031267 Not Cancer Driver No 76 0.097 376 43 0.114 0
RIN3 RIN3 Q8TB24 Ras and Rab interactor 3 chr14 GO:0031267 Not Cancer Driver No 137 0.139 417 61 0.146 0
RINL RINL Q6ZS11 Ras and Rab interactor-like protein chr19 GO:0031267 Not Cancer Driver No 50 0.088 367 32 0.087 0
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:0031267 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0031267 Not Cancer Driver No 44 0.139 33 2 0.061 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0031267 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0031267 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPH3A RPH3A Q9Y2J0 Rabphilin-3A chr12 GO:0031267 Not Cancer Driver No 155 0.223 427 105 0.246 0
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0031267 Not Cancer Driver No 40 0.127 162 20 0.123 0
RTKN RTKN Q9BST9 Rhotekin chr2 GO:0031267 Not Cancer Driver No 67 0.119 265 35 0.132 0
RUSC2 RUSC2 Q8N2Y8 AP-4 complex accessory subunit RUSC2 chr9 GO:0031267 Not Cancer Driver No 161 0.106 1142 115 0.101 0
SGSM1 SGSM1 Q2NKQ1 Small G protein signaling modulator 1 chr22 GO:0031267 Not Cancer Driver No 206 0.179 418 68 0.163 0
SGSM2_ENST00000426855 SGSM2 O43147 Small G protein signaling modulator 2 chr17 GO:0031267 Not Cancer Driver No 83 0.083 316 21 0.066 0
SGSM3 SGSM3 Q96HU1 Small G protein signaling modulator 3 chr22 GO:0031267 Not Cancer Driver No 83 0.111 77 9 0.117 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0031267 Not Cancer Driver No 143 0.148 241 43 0.178 0
SIKE1_ENST00000060969 SIKE1 Q9BRV8 Suppressor of IKBKE 1 chr1 GO:0031267 Not Cancer Driver No 23 0.111 107 9 0.084 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0031267 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0031267 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0031267 Not Cancer Driver No 82 0.125 293 39 0.133 0
SRGAP2 SRGAP2 O75044 SLIT-ROBO Rho GTPase-activating protein 2 chr1 GO:0031267 Not Cancer Driver No 122 0.114 541 71 0.131 0
STK19 STK19 P49842 Serine/threonine-protein kinase 19 chr6 GO:0031267 Not Cancer Driver No 60 0.163 129 28 0.217 0
STRIP1 STRIP1 Q5VSL9 Striatin-interacting protein 1 chr1 GO:0031267 Not Cancer Driver No 97 0.116 267 33 0.124 0
STRN3 STRN3 Q13033 Striatin-3 chr14 GO:0031267 Not Cancer Driver No 93 0.117 366 42 0.115 0
SYTL1_ENST00000616558 SYTL1 Q8IYJ3 Synaptotagmin-like protein 1 chr1 GO:0031267 Not Cancer Driver No 64 0.114 328 41 0.125 0
SYTL2_ENST00000528231 SYTL2 Q9HCH5 Synaptotagmin-like protein 2 chr11 GO:0031267 Not Cancer Driver No 137 0.147 635 104 0.164 0
SYTL3 SYTL3 Q4VX76 Synaptotagmin-like protein 3 chr6 GO:0031267 Not Cancer Driver No 87 0.143 200 24 0.12 0
SYTL4 SYTL4 Q96C24 Synaptotagmin-like protein 4 chrX GO:0031267 Not Cancer Driver No 116 0.173 267 34 0.127 0
SYTL5_ENST00000297875 SYTL5 Q8TDW5 Synaptotagmin-like protein 5 chrX GO:0031267 Not Cancer Driver No 127 0.174 347 53 0.153 0
TBC1D13 TBC1D13 Q9NVG8 TBC1 domain family member 13 chr9 GO:0031267 Not Cancer Driver No 49 0.122 57 10 0.175 0
TBC1D20 TBC1D20 Q96BZ9 TBC1 domain family member 20 chr20 GO:0031267 Not Cancer Driver No 52 0.129 99 10 0.101 0
TBC1D21 TBC1D21 Q8IYX1 TBC1 domain family member 21 chr15 GO:0031267 Not Cancer Driver No 62 0.185 7 0 0.0 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0031267 Not Cancer Driver No 51 0.174 1 0 0.0 0
TMEM127 TMEM127 O75204 Transmembrane protein 127 chr2 GO:0031267 Census Yes 24 0.101 41 5 0.122 7
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0031267 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNPO1 TNPO1 Q92973 Transportin-1 chr5 GO:0031267 Not Cancer Driver No 99 0.11 68 7 0.103 0
TNPO2 TNPO2 O14787 Transportin-2 chr19 GO:0031267 Not Cancer Driver No 99 0.11 76 10 0.132 0
TNPO3 TNPO3 Q9Y5L0 Transportin-3 chr7 GO:0031267 Not Cancer Driver No 122 0.132 12 1 0.083 1
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0031267 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRIP11 TRIP11 Q15643 Thyroid receptor-interacting protein 11 chr14 GO:0031267 Census, Compendium Yes 218 0.11 1364 161 0.118 2
TSC2 TSC2 P49815 Tuberin chr16 GO:0031267 Census, Compendium Yes 192 0.106 563 50 0.089 53
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0031267 Not Cancer Driver No 142 0.135 588 77 0.131 0
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0031267 Not Cancer Driver No 214 0.135 448 77 0.172 0
UNC13D UNC13D Q70J99 Protein unc-13 homolog D chr17 GO:0031267 Not Cancer Driver No 120 0.11 248 30 0.121 0
USP33_ENST00000357428 USP33 Q8TEY7 Ubiquitin carboxyl-terminal hydrolase 33 chr1 GO:0031267 Not Cancer Driver No 138 0.146 256 48 0.188 0
USP6NL_ENST00000609104 USP6NL Q92738 USP6 N-terminal-like protein chr10 GO:0031267 Not Cancer Driver No 113 0.136 472 81 0.172 0
VPS9D1 VPS9D1 Q9Y2B5 VPS9 domain-containing protein 1 chr16 GO:0031267 Not Cancer Driver No 57 0.09 353 26 0.074 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0031267 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0031267 Not Cancer Driver No 63 0.113 445 49 0.11 0
WHAMM WHAMM Q8TF30 WASP homolog-associated protein with actin, membranes and microtubules chr15 GO:0031267 Not Cancer Driver No 59 0.073 399 38 0.095 0
XPO1_ENST00000406957 XPO1 O14980 Exportin-1 chr2 GO:0031267 Census, Compendium Yes 140 0.131 33 9 0.273 0
XPO5 XPO5 Q9HAV4 Exportin-5 chr6 GO:0031267 Not Cancer Driver No 112 0.093 64 7 0.109 0
XPO6 XPO6 Q96QU8 Exportin-6 chr16 GO:0031267 Not Cancer Driver No 133 0.118 29 1 0.034 0
XPO7 XPO7 Q9UIA9 Exportin-7 chr8 GO:0031267 Not Cancer Driver No 132 0.121 59 8 0.136 0
XPOT XPOT O43592 Exportin-T chr12 GO:0031267 Not Cancer Driver No 114 0.119 0 0 0.0 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0031267 Not Cancer Driver No 49 0.132 359 47 0.131 0
YIPF1 YIPF1 Q9Y548 Protein YIPF1 chr1 GO:0031267 Not Cancer Driver No 37 0.121 70 4 0.057 0
YIPF2 YIPF2 Q9BWQ6 Protein YIPF2 chr19 GO:0031267 Not Cancer Driver No 24 0.076 70 3 0.043 0