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Total number of protein in "GO:0030335" GO term:  494

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAMP_ENST00000248450 AAMP Q13685 Angio-associated migratory cell protein chr2 GO:0030335 Not Cancer Driver No 31 0.071 126 10 0.079 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0030335 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACKR3 ACKR3 P25106 Atypical chemokine receptor 3 chr2 GO:0030335 Census, Compendium Yes 78 0.215 0 0 0.0 1
ACTA2 ACTA2 P62736 Actin, aortic smooth muscle chr10 GO:0030335 Not Cancer Driver No 50 0.133 39 4 0.103 17
ACTG1_ENST00000575087 ACTG1 P63261 Actin, cytoplasmic 2 chr17 GO:0030335 Not Cancer Driver No 73 0.195 42 10 0.238 16
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0030335 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0030335 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0030335 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0030335 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0030335 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0030335 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0030335 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADAMTS1 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 GO:0030335 Not Cancer Driver No 135 0.14 272 32 0.118 0
ADGRA2 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0030335 Not Cancer Driver No 140 0.105 417 32 0.077 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0030335 Not Cancer Driver No 67 0.144 161 10 0.062 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0030335 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0030335 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGT AGT P01019 Angiotensinogen chr1 GO:0030335 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0030335 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0030335 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKIRIN1 AKIRIN1 Q9H9L7 Akirin-1 chr1 GO:0030335 Not Cancer Driver No 11 0.057 125 9 0.072 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0030335 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0030335 Census Yes 77 0.16 84 9 0.107 2
AKT3_ENST00000366539 AKT3 Q9Y243 RAC-gamma serine/threonine-protein kinase chr1 GO:0030335 Census, Compendium Yes 92 0.192 131 24 0.183 3
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0030335 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT4 ANGPT4 Q9Y264 Angiopoietin-4 chr20 GO:0030335 Not Cancer Driver No 104 0.207 150 32 0.213 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0030335 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0030335 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0030335 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0030335 Not Cancer Driver No 53 0.164 22 4 0.182 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0030335 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APELA APELA P0DMC3 Apelin receptor early endogenous ligand chr4 GO:0030335 Not Cancer Driver No 1 0.019 0 0 0.0 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0030335 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0030335 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0030335 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF39 ARHGEF39 Q8N4T4 Rho guanine nucleotide exchange factor 39 chr9 GO:0030335 Not Cancer Driver No 45 0.134 56 5 0.089 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0030335 Not Cancer Driver No 106 0.132 301 39 0.13 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0030335 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0030335 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0030335 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0030335 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0030335 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATP8A1 ATP8A1 Q9Y2Q0 Phospholipid-transporting ATPase IA chr4 GO:0030335 Not Cancer Driver No 185 0.159 84 7 0.083 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0030335 Not Cancer Driver No 55 0.12 402 49 0.122 0
BCAR1_ENST00000162330 BCAR1 P56945 Breast cancer anti-estrogen resistance protein 1 chr16 GO:0030335 Not Cancer Driver No 108 0.124 677 75 0.111 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0030335 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0030335 Census, Compendium Yes 24 0.1 72 5 0.069 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0030335 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0030335 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0030335 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0030335 Compendium Yes 141 0.136 601 70 0.116 19
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0030335 Not Cancer Driver No 14 0.05 103 6 0.058 2
C3AR1 C3AR1 Q16581 C3a anaphylatoxin chemotactic receptor chr12 GO:0030335 Not Cancer Driver No 88 0.183 72 16 0.222 0
C5AR1 C5AR1 P21730 C5a anaphylatoxin chemotactic receptor 1 chr19 GO:0030335 Not Cancer Driver No 71 0.203 0 0 0.0 0
CALR CALR P27797 Calreticulin chr19 GO:0030335 Census Yes 45 0.108 245 31 0.127 0
CAMK1D CAMK1D Q8IU85 Calcium/calmodulin-dependent protein kinase type 1D chr10 GO:0030335 Not Cancer Driver No 90 0.234 42 14 0.333 0
CAPN7 CAPN7 Q9Y6W3 Calpain-7 chr3 GO:0030335 Not Cancer Driver No 80 0.098 92 9 0.098 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0030335 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0030335 Not Cancer Driver No 154 0.107 669 75 0.112 4
CASS4 CASS4 Q9NQ75 Cas scaffolding protein family member 4 chr20 GO:0030335 Not Cancer Driver No 204 0.26 496 137 0.276 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0030335 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0030335 Not Cancer Driver No 72 0.147 373 49 0.131 0
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 GO:0030335 Not Cancer Driver No 145 0.126 771 76 0.099 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0030335 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCL1 CCL1 P22362 C-C motif chemokine 1 chr17 GO:0030335 Not Cancer Driver No 27 0.281 0 0 0.0 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0030335 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0030335 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL20 CCL20 P78556 C-C motif chemokine 20 chr2 GO:0030335 Not Cancer Driver No 16 0.167 0 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0030335 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL24_ENST00000222902 CCL24 O00175 C-C motif chemokine 24 chr7 GO:0030335 Not Cancer Driver No 25 0.21 23 3 0.13 0
CCL26_ENST00000005180 CCL26 Q9Y258 C-C motif chemokine 26 chr7 GO:0030335 Not Cancer Driver No 9 0.096 0 0 0.0 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0030335 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCL7 CCL7 P80098 C-C motif chemokine 7 chr17 GO:0030335 Not Cancer Driver No 30 0.303 13 3 0.231 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0030335 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN4 CCN4 O95388 CCN family member 4 chr8 GO:0030335 Not Cancer Driver No 93 0.253 20 8 0.4 0
CCR1 CCR1 P32246 C-C chemokine receptor type 1 chr3 GO:0030335 Not Cancer Driver No 69 0.194 14 5 0.357 0
CCR2_ENST00000400888 CCR2 P41597 C-C chemokine receptor type 2 chr3 GO:0030335 Not Cancer Driver No 81 0.217 23 1 0.043 0
CCR6_ENST00000349984 CCR6 P51684 C-C chemokine receptor type 6 chr6 GO:0030335 Not Cancer Driver No 56 0.15 13 2 0.154 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0030335 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD151_ENST00000322008 CD151 P48509 CD151 antigen chr11 GO:0030335 Not Cancer Driver No 26 0.103 4 0 0.0 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0030335 Census Yes 29 0.1 54 9 0.167 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0030335 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0030335 Not Cancer Driver No 37 0.115 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0030335 Census Yes 31 0.105 185 20 0.108 0
CD99 CD99 P14209 CD99 antigen chrX GO:0030335 Not Cancer Driver No 22 0.119 143 19 0.133 0
CD99L2_ENST00000370377 CD99L2 Q8TCZ2 CD99 antigen-like protein 2 chrX GO:0030335 Not Cancer Driver No 57 0.218 193 47 0.244 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0030335 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0030335 Not Cancer Driver No 144 0.184 305 55 0.18 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0030335 Not Cancer Driver No 63 0.183 110 19 0.173 0
CEMIP_ENST00000356249 CEMIP Q8WUJ3 Cell migration-inducing and hyaluronan-binding protein chr15 GO:0030335 Not Cancer Driver No 207 0.152 105 10 0.095 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0030335 Not Cancer Driver No 28 0.241 0 0 0.0 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0030335 Not Cancer Driver No 24 0.126 6 1 0.167 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0030335 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0030335 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0030335 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0030335 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0030335 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0030335 Not Cancer Driver No 43 0.174 46 2 0.043 0
CMKLR1 CMKLR1 Q99788 Chemerin-like receptor 1 chr12 GO:0030335 Not Cancer Driver No 107 0.287 24 13 0.542 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0030335 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0030335 Not Cancer Driver No 51 0.111 126 15 0.119 1
CPNE3 CPNE3 O75131 Copine-3 chr8 GO:0030335 Not Cancer Driver No 79 0.147 33 5 0.152 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0030335 Not Cancer Driver No 33 0.089 168 11 0.065 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0030335 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0030335 Not Cancer Driver No 38 0.125 160 25 0.156 0
CSF1R CSF1R P07333 Macrophage colony-stimulating factor 1 receptor chr5 GO:0030335 Census Yes 133 0.137 124 17 0.137 20
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0030335 Not Cancer Driver No 69 0.125 339 46 0.136 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0030335 Not Cancer Driver No 45 0.134 4 0 0.0 0
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0030335 Not Cancer Driver No 66 0.166 259 44 0.17 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0030335 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0030335 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0030335 Not Cancer Driver No 16 0.172 0 0 0.0 0
CXCL13 CXCL13 O43927 C-X-C motif chemokine 13 chr4 GO:0030335 Not Cancer Driver No 11 0.101 0 0 0.0 0
CXCL17 CXCL17 Q6UXB2 C-X-C motif chemokine 17 chr19 GO:0030335 Not Cancer Driver No 8 0.067 44 6 0.136 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0030335 Not Cancer Driver No 17 0.172 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0030335 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0030335 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0030335 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0030335 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0030335 Not Cancer Driver No 55 0.149 53 9 0.17 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0030335 Not Cancer Driver No 56 0.123 82 7 0.085 0
DDR2 DDR2 Q16832 Discoidin domain-containing receptor 2 chr1 GO:0030335 Census Yes 192 0.225 118 34 0.288 7
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0030335 Not Cancer Driver No 34 0.108 181 23 0.127 0
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0030335 Not Cancer Driver No 9 0.127 3 0 0.0 0
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0030335 Not Cancer Driver No 118 0.093 692 57 0.082 1
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0030335 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0030335 Not Cancer Driver No 67 0.091 212 23 0.108 7
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0030335 Not Cancer Driver No 240 0.129 360 52 0.144 0
DOCK4 DOCK4 Q8N1I0 Dedicator of cytokinesis protein 4 chr7 GO:0030335 Not Cancer Driver No 331 0.168 397 80 0.202 0
DOCK5 DOCK5 Q9H7D0 Dedicator of cytokinesis protein 5 chr8 GO:0030335 Not Cancer Driver No 278 0.149 330 45 0.136 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0030335 Not Cancer Driver No 262 0.122 454 53 0.117 0
DOCK8 DOCK8 Q8NF50 Dedicator of cytokinesis protein 8 chr9 GO:0030335 Not Cancer Driver No 321 0.153 312 60 0.192 1
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0030335 Not Cancer Driver No 73 0.164 30 4 0.133 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0030335 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0030335 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0030335 Census, Compendium Yes 444 0.367 223 35 0.157 1
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0030335 Not Cancer Driver No 60 0.11 19 4 0.211 0
ELP5_ENST00000354429 ELP5 Q8TE02 Elongator complex protein 5 chr17 GO:0030335 Not Cancer Driver No 33 0.104 131 14 0.107 0
ELP6 ELP6 Q0PNE2 Elongator complex protein 6 chr3 GO:0030335 Not Cancer Driver No 30 0.113 3 0 0.0 0
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0030335 Not Cancer Driver No 25 0.095 109 15 0.138 0
ENPP2_ENST00000075322 ENPP2 Q13822 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 chr8 GO:0030335 Not Cancer Driver No 168 0.195 81 16 0.198 0
EPB41L4B EPB41L4B Q9H329 Band 4.1-like protein 4B chr9 GO:0030335 Not Cancer Driver No 131 0.146 548 77 0.141 0
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0030335 Not Cancer Driver No 97 0.132 312 45 0.144 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0030335 Not Cancer Driver No 147 0.151 211 38 0.18 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0030335 Compendium Yes 171 0.175 187 39 0.209 3
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0030335 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0030335 Not Cancer Driver No 186 0.176 119 17 0.143 7
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0030335 Not Cancer Driver No 68 0.154 78 9 0.115 0
F10 F10 P00742 Coagulation factor X chr13 GO:0030335 Not Cancer Driver No 98 0.201 120 24 0.2 26
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0030335 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0030335 Not Cancer Driver No 55 0.139 7 2 0.286 0
F3 F3 P13726 Tissue factor chr1 GO:0030335 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0030335 Not Cancer Driver No 74 0.159 50 7 0.14 108
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0030335 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0030335 Not Cancer Driver No 25 0.174 141 24 0.17 0
FAM110C FAM110C Q1W6H9 Protein FAM110C chr2 GO:0030335 Not Cancer Driver No 33 0.103 286 32 0.112 0
FAM83H FAM83H Q6ZRV2 Protein FAM83H chr8 GO:0030335 Not Cancer Driver No 151 0.128 893 95 0.106 1
FAM89B FAM89B Q8N5H3 Leucine repeat adapter protein 25 chr11 GO:0030335 Not Cancer Driver No 14 0.074 108 11 0.102 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0030335 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0030335 Not Cancer Driver No 48 0.107 113 13 0.115 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0030335 Not Cancer Driver No 114 0.139 145 21 0.145 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0030335 Not Cancer Driver No 100 0.148 65 8 0.123 2
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0030335 Not Cancer Driver No 71 0.104 101 10 0.099 0
FERMT3 FERMT3 Q86UX7 Fermitin family homolog 3 chr11 GO:0030335 Not Cancer Driver No 99 0.148 108 14 0.13 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0030335 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF16 FGF16 O43320 Fibroblast growth factor 16 chrX GO:0030335 Not Cancer Driver No 29 0.14 28 6 0.214 1
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0030335 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0030335 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0030335 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF7 FGF7 P21781 Fibroblast growth factor 7 chr15 GO:0030335 Not Cancer Driver No 38 0.196 22 4 0.182 0
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0030335 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 GO:0030335 Not Cancer Driver No 28 0.12 81 8 0.099 0
FGFR1OP CEP43 O95684 Centrosomal protein 43 chr6 GO:0030335 Not Cancer Driver No 43 0.108 272 33 0.121 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0030335 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0030335 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0030335 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0030335 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:0030335 Compendium Yes 394 0.159 1243 185 0.149 8
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0030335 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0030335 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0030335 Census Yes 75 0.149 441 61 0.138 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0030335 Census, Compendium Yes 109 0.161 448 71 0.158 3
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0030335 Not Cancer Driver No 96 0.274 26 5 0.192 0
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0030335 Not Cancer Driver No 31 0.24 0 0 0.0 1
FUT1_ENST00000645652 FUT1 P19526 Galactoside alpha-(1,2)-fucosyltransferase 1 chr19 GO:0030335 Not Cancer Driver No 63 0.173 17 3 0.176 0
FUT4 FUT4 P22083 Alpha-(1,3)-fucosyltransferase 4 chr11 GO:0030335 Not Cancer Driver No 49 0.092 193 9 0.047 0
FUT7 FUT7 Q11130 Alpha-(1,3)-fucosyltransferase 7 chr9 GO:0030335 Not Cancer Driver No 28 0.082 25 3 0.12 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0030335 Not Cancer Driver No 57 0.106 33 5 0.152 19
GAB1_ENST00000262994 GAB1 Q13480 GRB2-associated-binding protein 1 chr4 GO:0030335 Not Cancer Driver No 79 0.114 570 68 0.119 1
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0030335 Not Cancer Driver No 82 0.121 42 6 0.143 0
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0030335 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0030335 Census, Compendium Yes 111 0.251 364 87 0.239 2
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0030335 Not Cancer Driver No 40 0.1 3 0 0.0 0
GLIPR2 GLIPR2 Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 chr9 GO:0030335 Not Cancer Driver No 16 0.104 77 10 0.13 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0030335 Compendium Yes 50 0.141 24 0 0.0 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0030335 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0030335 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0030335 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPNMB GPNMB Q14956 Transmembrane glycoprotein NMB chr7 GO:0030335 Not Cancer Driver No 89 0.156 94 18 0.191 0
GRB7_ENST00000394209 GRB7 Q14451 Growth factor receptor-bound protein 7 chr17 GO:0030335 Not Cancer Driver No 84 0.158 134 27 0.201 0
GRN GRN P28799 Progranulin chr17 GO:0030335 Not Cancer Driver No 76 0.128 29 6 0.207 1
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0030335 Not Cancer Driver No 100 0.181 17 7 0.412 0
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0030335 Not Cancer Driver No 16 0.077 63 3 0.048 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0030335 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0030335 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0030335 Not Cancer Driver No 286 0.283 631 178 0.282 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0030335 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0030335 Census Yes 118 0.143 435 51 0.117 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0030335 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0030335 Not Cancer Driver No 46 0.16 81 13 0.16 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0030335 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0030335 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0030335 Not Cancer Driver No 10 0.049 118 8 0.068 20
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0030335 Not Cancer Driver No 47 0.108 9 0 0.0 1
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0030335 Not Cancer Driver No 61 0.115 251 28 0.112 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0030335 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0030335 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0030335 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0030335 Not Cancer Driver No 27 0.099 112 17 0.152 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0030335 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0030335 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0030335 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL23A IL23A Q9NPF7 Interleukin-23 subunit alpha chr12 GO:0030335 Not Cancer Driver No 15 0.079 42 3 0.071 0
IL34 IL34 Q6ZMJ4 Interleukin-34 chr16 GO:0030335 Not Cancer Driver No 22 0.091 42 6 0.143 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0030335 Not Cancer Driver No 18 0.118 0 0 0.0 0
INS INS P01308 Insulin chr11 GO:0030335 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0030335 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSM1 INSM1 Q01101 Insulinoma-associated protein 1 chr20 GO:0030335 Not Cancer Driver No 25 0.049 359 12 0.033 0
INSR INSR P06213 Insulin receptor chr19 GO:0030335 Not Cancer Driver No 190 0.137 280 57 0.204 64
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 GO:0030335 Not Cancer Driver No 141 0.146 610 97 0.159 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0030335 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0030335 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0030335 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0030335 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0030335 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGA6_ENST00000442250 ITGA6 P23229 Integrin alpha-6 chr2 GO:0030335 Not Cancer Driver No 130 0.115 226 29 0.128 0
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0030335 Census Yes 153 0.146 92 9 0.098 0
ITGAX_ENST00000268296 ITGAX P20702 Integrin alpha-X chr16 GO:0030335 Not Cancer Driver No 245 0.211 82 15 0.183 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0030335 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0030335 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0030335 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0030335 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAM2_ENST00000480456 JAM2 P57087 Junctional adhesion molecule B chr21 GO:0030335 Not Cancer Driver No 63 0.211 64 16 0.25 2
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0030335 Not Cancer Driver No 50 0.161 62 11 0.177 2
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0030335 Not Cancer Driver No 291 0.214 1337 290 0.217 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0030335 Census Yes 35 0.106 281 25 0.089 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0030335 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIF20B KIF20B Q96Q89 Kinesin-like protein KIF20B chr10 GO:0030335 Not Cancer Driver No 217 0.119 902 109 0.121 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0030335 Census, Compendium Yes 226 0.232 83 33 0.398 21
LAMB1 LAMB1 P07942 Laminin subunit beta-1 chr7 GO:0030335 Not Cancer Driver No 240 0.134 418 50 0.12 0
LAMC2 LAMC2 Q13753 Laminin subunit gamma-2 chr1 GO:0030335 Not Cancer Driver No 165 0.138 496 68 0.137 0
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0030335 Not Cancer Driver No 84 0.175 6 0 0.0 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0030335 Census Yes 64 0.16 370 57 0.154 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0030335 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0030335 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0030335 Not Cancer Driver No 57 0.132 112 19 0.17 0
LGR6 LGR6 Q9HBX8 Leucine-rich repeat-containing G-protein coupled receptor 6 chr1 GO:0030335 Not Cancer Driver No 163 0.169 101 16 0.158 0
LRRC15_ENST00000347624 LRRC15 Q8TF66 Leucine-rich repeat-containing protein 15 chr3 GO:0030335 Not Cancer Driver No 124 0.213 37 11 0.297 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0030335 Census Yes 95 0.186 84 12 0.143 0
LYVE1 LYVE1 Q9Y5Y7 Lymphatic vessel endothelial hyaluronic acid receptor 1 chr11 GO:0030335 Not Cancer Driver No 34 0.106 77 13 0.169 0
MADCAM1 MADCAM1 Q13477 Mucosal addressin cell adhesion molecule 1 chr19 GO:0030335 Not Cancer Driver No 39 0.102 240 33 0.138 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0030335 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0030335 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0030335 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0030335 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0030335 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0030335 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:0030335 Not Cancer Driver No 50 0.153 176 28 0.159 3
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0030335 Not Cancer Driver No 46 0.096 249 22 0.088 0
MCAM MCAM P43121 Cell surface glycoprotein MUC18 chr11 GO:0030335 Not Cancer Driver No 91 0.141 305 46 0.151 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0030335 Not Cancer Driver No 41 0.117 13 0 0.0 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0030335 Not Cancer Driver No 15 0.105 20 2 0.1 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0030335 Census, Compendium Yes 226 0.163 62 15 0.242 19
MGAT5_ENST00000281923 MGAT5 Q09328 Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A chr2 GO:0030335 Not Cancer Driver No 106 0.143 24 2 0.083 0
MIEN1_ENST00000394231 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0030335 Not Cancer Driver No 17 0.148 37 4 0.108 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0030335 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0030335 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP7 MMP7 P09237 Matrilysin chr11 GO:0030335 Not Cancer Driver No 39 0.146 70 2 0.029 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0030335 Not Cancer Driver No 129 0.182 124 26 0.21 0
MOSPD2 MOSPD2 Q8NHP6 Motile sperm domain-containing protein 2 chrX GO:0030335 Not Cancer Driver No 58 0.112 143 16 0.112 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0030335 Not Cancer Driver No 68 0.181 64 11 0.172 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0030335 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0030335 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0030335 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYLK MYLK Q15746 Myosin light chain kinase, smooth muscle chr3 GO:0030335 Not Cancer Driver No 343 0.179 957 184 0.192 3
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0030335 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYOC MYOC Q99972 Myocilin chr1 GO:0030335 Not Cancer Driver No 92 0.183 196 43 0.219 58
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0030335 Not Cancer Driver No 247 0.219 51 10 0.196 4
NEDD9 NEDD9 Q14511 Enhancer of filamentation 1 chr6 GO:0030335 Not Cancer Driver No 106 0.127 516 72 0.14 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0030335 Census, Compendium Yes 228 0.377 402 62 0.154 4
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0030335 Compendium Yes 353 0.126 1528 184 0.12 37
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0030335 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0030335 Census, Compendium Yes 363 0.142 686 87 0.127 3
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0030335 Census Yes 83 0.133 298 37 0.124 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0030335 Compendium Yes 146 0.158 211 31 0.147 0
NRP2 NRP2 O60462 Neuropilin-2 chr2 GO:0030335 Not Cancer Driver No 161 0.173 207 45 0.217 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0030335 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0030335 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0030335 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 GO:0030335 Not Cancer Driver No 70 0.108 490 58 0.118 0
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0030335 Not Cancer Driver No 21 0.072 13 0 0.0 1
ONECUT1 ONECUT1 Q9UBC0 Hepatocyte nuclear factor 6 chr15 GO:0030335 Not Cancer Driver No 78 0.168 405 65 0.16 0
ONECUT2 ONECUT2 O95948 One cut domain family member 2 chr18 GO:0030335 Not Cancer Driver No 76 0.151 408 54 0.132 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0030335 Not Cancer Driver No 69 0.131 208 29 0.139 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0030335 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0030335 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0030335 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0030335 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0030335 Not Cancer Driver No 127 0.227 286 64 0.224 2
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0030335 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCD6 PDCD6 O75340 Programmed cell death protein 6 chr5 GO:0030335 Not Cancer Driver No 21 0.11 24 1 0.042 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0030335 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0030335 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0030335 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0030335 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0030335 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0030335 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0030335 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0030335 Not Cancer Driver No 37 0.228 96 24 0.25 0
PECAM1 PECAM1 P16284 Platelet endothelial cell adhesion molecule chr17 GO:0030335 Not Cancer Driver No 2 0.003 153 2 0.013 0
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0030335 Not Cancer Driver No 16 0.114 7 1 0.143 3
PGF_ENST00000405431 PGF P49763 Placenta growth factor chr14 GO:0030335 Not Cancer Driver No 30 0.136 72 10 0.139 0
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 GO:0030335 Not Cancer Driver No 187 0.111 350 43 0.123 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0030335 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0030335 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0030335 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0030335 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0030335 Not Cancer Driver No 51 0.111 149 20 0.134 0
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0030335 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLAA PLAA Q9Y263 Phospholipase A-2-activating protein chr9 GO:0030335 Not Cancer Driver No 78 0.098 150 14 0.093 2
PLAU PLAU P00749 Urokinase-type plasminogen activator chr10 GO:0030335 Not Cancer Driver No 59 0.137 10 0 0.0 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0030335 Census, Compendium Yes 158 0.122 186 21 0.113 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0030335 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLET1 PLET1 Q6UQ28 Placenta-expressed transcript 1 protein chr11 GO:0030335 Not Cancer Driver No 8 0.039 0 0 0.0 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0030335 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLP1 PLP1 P60201 Myelin proteolipid protein chrX GO:0030335 Not Cancer Driver No 49 0.177 5 1 0.2 72
PLVAP PLVAP Q9BX97 Plasmalemma vesicle-associated protein chr19 GO:0030335 Not Cancer Driver No 96 0.217 174 39 0.224 1
PODXL PODXL O00592 Podocalyxin chr7 GO:0030335 Not Cancer Driver No 69 0.124 432 56 0.13 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0030335 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0030335 Compendium Yes 85 0.163 140 27 0.193 7
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0030335 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0030335 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0030335 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0030335 Compendium Yes 118 0.134 246 34 0.138 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0030335 Not Cancer Driver No 182 0.247 537 141 0.263 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0030335 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0030335 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0030335 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0030335 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTP4A1 PTP4A1 Q93096 Protein tyrosine phosphatase type IVA 1 chr6 GO:0030335 Not Cancer Driver No 21 0.121 2 0 0.0 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0030335 Census, Compendium Yes 315 0.241 462 107 0.232 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0030335 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0030335 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB25 RAB25 P57735 Ras-related protein Rab-25 chr1 GO:0030335 Not Cancer Driver No 26 0.122 32 5 0.156 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0030335 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAC2 RAC2 P15153 Ras-related C3 botulinum toxin substrate 2 chr22 GO:0030335 Not Cancer Driver No 31 0.161 0 0 0.0 2
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0030335 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0030335 Not Cancer Driver No 216 0.144 803 116 0.144 0
RARRES2 RARRES2 Q99969 Retinoic acid receptor responder protein 2 chr7 GO:0030335 Not Cancer Driver No 16 0.098 14 2 0.143 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0030335 Not Cancer Driver No 71 0.122 297 37 0.125 1
RELN RELN P78509 Reelin chr7 GO:0030335 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0030335 Census, Compendium Yes 208 0.187 105 12 0.114 139
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0030335 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0030335 Not Cancer Driver No 52 0.265 19 2 0.105 0
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0030335 Not Cancer Driver No 30 0.155 53 7 0.132 0
RHOD RHOD O00212 Rho-related GTP-binding protein RhoD chr11 GO:0030335 Not Cancer Driver No 20 0.095 10 0 0.0 0
RHOJ RHOJ Q9H4E5 Rho-related GTP-binding protein RhoJ chr14 GO:0030335 Not Cancer Driver No 39 0.182 0 0 0.0 0
RIPOR1_ENST00000379312 RIPOR1 Q6ZS17 Rho family-interacting cell polarization regulator 1 chr16 GO:0030335 Not Cancer Driver No 125 0.102 687 71 0.103 0
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0030335 Not Cancer Driver No 131 0.123 421 76 0.181 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0030335 Not Cancer Driver No 145 0.104 732 81 0.111 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0030335 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0030335 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRAS RRAS P10301 Ras-related protein R-Ras chr19 GO:0030335 Not Cancer Driver No 25 0.115 71 6 0.085 0
RRAS2 RRAS2 P62070 Ras-related protein R-Ras2 chr11 GO:0030335 Compendium Yes 29 0.142 37 1 0.027 4
RREB1_ENST00000349384 RREB1 Q92766 Ras-responsive element-binding protein 1 chr6 GO:0030335 Not Cancer Driver No 213 0.126 1152 144 0.125 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0030335 Not Cancer Driver No 121 0.102 866 82 0.095 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0030335 Not Cancer Driver No 75 0.16 204 29 0.142 0
S100A11 S100A11 P31949 Protein S100-A11 chr1 GO:0030335 Not Cancer Driver No 13 0.124 14 2 0.143 0
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0030335 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A7_ENST00000368722 S100A7 P31151 Protein S100-A7 chr1 GO:0030335 Census Yes 39 0.386 28 14 0.5 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0030335 Not Cancer Driver No 86 0.225 29 6 0.207 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0030335 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0030335 Not Cancer Driver No 53 0.096 6 1 0.167 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0030335 Not Cancer Driver No 39 0.131 17 2 0.118 0
SELENOK SELENOK Q9Y6D0 Selenoprotein K chr3 GO:0030335 Not Cancer Driver No 10 0.106 47 6 0.128 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0030335 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0030335 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0030335 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0030335 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0030335 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0030335 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0030335 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0030335 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0030335 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0030335 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0030335 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0030335 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0030335 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0030335 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0030335 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0030335 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0030335 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0030335 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0030335 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0030335 Not Cancer Driver No 81 0.122 150 21 0.14 0
SERPINB3 SERPINB3 P29508 Serpin B3 chr18 GO:0030335 Not Cancer Driver No 142 0.364 47 28 0.596 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0030335 Not Cancer Driver No 78 0.194 7 2 0.286 0
SH3RF2 SH3RF2 Q8TEC5 E3 ubiquitin-protein ligase SH3RF2 chr5 GO:0030335 Not Cancer Driver No 151 0.207 455 101 0.222 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0030335 Census Yes 68 0.108 470 52 0.111 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0030335 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLAMF1_ENST00000302035 SLAMF1 Q13291 Signaling lymphocytic activation molecule chr1 GO:0030335 Not Cancer Driver No 82 0.245 64 10 0.156 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0030335 Not Cancer Driver No 305 0.313 158 48 0.304 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0030335 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMIM22_ENST00000589721 SMIM22 K7EJ46 Small integral membrane protein 22 chr16 GO:0030335 Not Cancer Driver No 1 0.012 20 1 0.05 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0030335 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0030335 Not Cancer Driver No 82 0.184 216 52 0.241 0
SMURF2 SMURF2 Q9HAU4 E3 ubiquitin-protein ligase SMURF2 chr17 GO:0030335 Not Cancer Driver No 87 0.116 242 28 0.116 0
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0030335 Not Cancer Driver No 52 0.197 97 11 0.113 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0030335 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0030335 Not Cancer Driver No 32 0.144 25 5 0.2 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0030335 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0030335 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0030335 Not Cancer Driver No 128 0.097 841 81 0.096 0
SPARC SPARC P09486 SPARC chr5 GO:0030335 Not Cancer Driver No 60 0.198 69 5 0.072 2
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0030335 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0030335 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0030335 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPRY2 SPRY2 O43597 Protein sprouty homolog 2 chr13 GO:0030335 Not Cancer Driver No 46 0.146 169 29 0.172 1
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0030335 Census Yes 53 0.099 130 11 0.085 1
SRGAP2C SRGAP2C P0DJJ0 SLIT-ROBO Rho GTPase-activating protein 2C chr1 GO:0030335 Not Cancer Driver No 2 0.004 135 2 0.015 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0030335 Not Cancer Driver No 86 0.185 64 13 0.203 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0030335 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5A_ENST00000590949 STAT5A P42229 Signal transducer and activator of transcription 5A chr17 GO:0030335 Not Cancer Driver No 89 0.112 125 14 0.112 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0030335 Not Cancer Driver No 64 0.117 182 19 0.104 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0030335 Not Cancer Driver No 70 0.144 231 30 0.13 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0030335 Not Cancer Driver No 50 0.168 152 20 0.132 0
SUN2_ENST00000405510 SUN2 Q9UH99 SUN domain-containing protein 2 chr22 GO:0030335 Not Cancer Driver No 74 0.103 214 18 0.084 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0030335 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYDE1 SYDE1 Q6ZW31 Rho GTPase-activating protein SYDE1 chr19 GO:0030335 Not Cancer Driver No 62 0.084 412 27 0.066 0
SYNE2_ENST00000344113 SYNE2 Q8WXH0 Nesprin-2 chr14 GO:0030335 Not Cancer Driver No 779 0.113 1888 220 0.117 1
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0030335 Not Cancer Driver No 69 0.17 28 2 0.071 0
TCAF2_ENST00000441159 TCAF2 A6NFQ2 TRPM8 channel-associated factor 2 chr7 GO:0030335 Not Cancer Driver No 61 0.066 38 12 0.316 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0030335 Not Cancer Driver No 39 0.207 25 2 0.08 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0030335 Not Cancer Driver No 219 0.195 126 22 0.175 10
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0030335 Census Yes 110 0.097 212 16 0.075 31
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0030335 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0030335 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0030335 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0030335 Census, Compendium Yes 106 0.187 60 16 0.267 25
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0030335 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0030335 Not Cancer Driver No 137 0.143 281 40 0.142 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0030335 Not Cancer Driver No 24 0.149 5 0 0.0 0
TIAM1 TIAM1 Q13009 Rho guanine nucleotide exchange factor TIAM1 chr21 GO:0030335 Not Cancer Driver No 370 0.233 810 194 0.24 0
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0030335 Not Cancer Driver No 28 0.127 80 6 0.075 0
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0030335 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0030335 Not Cancer Driver No 292 0.348 0 0 0.0 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0030335 Not Cancer Driver No 38 0.075 141 13 0.092 0
TMSB15B TMSB15B P0CG35 Thymosin beta-15B chrX GO:0030335 Not Cancer Driver No 7 0.156 45 7 0.156 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0030335 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0030335 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP6 TNFAIP6 P98066 Tumor necrosis factor-inducible gene 6 protein chr2 GO:0030335 Not Cancer Driver No 62 0.224 13 5 0.385 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0030335 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0030335 Not Cancer Driver No 58 0.242 18 1 0.056 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0030335 Not Cancer Driver No 26 0.083 74 5 0.068 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0030335 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0030335 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIP6 TRIP6 Q15654 Thyroid receptor-interacting protein 6 chr7 GO:0030335 Not Cancer Driver No 62 0.13 268 19 0.071 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0030335 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSTA3_ENST00000529064 GFUS Q13630 GDP-L-fucose synthase chr8 GO:0030335 Not Cancer Driver No 38 0.118 19 2 0.105 0
TWIST2 TWIST2 Q8WVJ9 Twist-related protein 2 chr2 GO:0030335 Not Cancer Driver No 11 0.069 90 2 0.022 4
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0030335 Not Cancer Driver No 27 0.116 41 7 0.171 0
VEGFB VEGFB P49765 Vascular endothelial growth factor B chr11 GO:0030335 Not Cancer Driver No 25 0.121 125 22 0.176 0
VEGFC VEGFC P49767 Vascular endothelial growth factor C chr4 GO:0030335 Not Cancer Driver No 128 0.305 37 12 0.324 0
VEGFD VEGFD O43915 Vascular endothelial growth factor D chrX GO:0030335 Not Cancer Driver No 59 0.167 33 6 0.182 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0030335 Not Cancer Driver No 124 0.15 222 38 0.171 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0030335 Not Cancer Driver No 52 0.167 135 19 0.141 0
VTN VTN P04004 Vitronectin chr17 GO:0030335 Not Cancer Driver No 76 0.159 168 29 0.173 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0030335 Not Cancer Driver No 6 0.013 336 6 0.018 0
WDR62_ENST00000270301 WDR62 O43379 WD repeat-containing protein 62 chr19 GO:0030335 Not Cancer Driver No 181 0.119 792 100 0.126 5
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0030335 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0030335 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0030335 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0030335 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0030335 Not Cancer Driver No 93 0.266 18 9 0.5 4
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0030335 Not Cancer Driver No 19 0.073 169 9 0.053 0
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0030335 Not Cancer Driver No 28 0.246 35 11 0.314 0
XCL2 XCL2 Q9UBD3 Cytokine SCM-1 beta chr1 GO:0030335 Not Cancer Driver No 20 0.175 35 5 0.143 0
XG_ENST00000381174 XG P55808 Glycoprotein Xg chrX GO:0030335 Not Cancer Driver No 27 0.15 140 23 0.164 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0030335 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZNF268_ENST00000228289 ZNF268 Q14587 Zinc finger protein 268 chr12 GO:0030335 Not Cancer Driver No 96 0.101 63 9 0.143 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0030335 Not Cancer Driver No 126 0.191 54 12 0.222 0
ZNF580_ENST00000545125 ZNF580 Q9UK33 Zinc finger protein 580 chr19 GO:0030335 Not Cancer Driver No 8 0.047 153 8 0.052 0
ZNF609 ZNF609 O15014 Zinc finger protein 609 chr15 GO:0030335 Not Cancer Driver No 141 0.1 1333 133 0.1 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0030335 Not Cancer Driver No 26 0.044 415 14 0.034 0