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Total number of protein in "GO:0030162" GO term:  230

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACP4 ACP4 Q9BZG2 Testicular acid phosphatase chr19 GO:0030162 Not Cancer Driver No 66 0.155 28 7 0.25 3
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0030162 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0030162 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0030162 Not Cancer Driver No 67 0.144 161 10 0.062 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0030162 Not Cancer Driver No 31 0.077 297 21 0.071 0
ANGPTL8_ENST00000252453 ANGPTL8 Q6UXH0 Angiopoietin-like protein 8 chr19 GO:0030162 Not Cancer Driver No 17 0.086 26 6 0.231 0
ANTXR1 ANTXR1 Q9H6X2 Anthrax toxin receptor 1 chr2 GO:0030162 Not Cancer Driver No 105 0.186 183 44 0.24 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0030162 Not Cancer Driver No 49 0.145 20 4 0.2 0
ANXA8L1 ANXA8L1 Q5VT79 Annexin A8-like protein 1 chr10 GO:0030162 Not Cancer Driver No 5 0.015 37 0 0.0 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0030162 Not Cancer Driver No 127 0.102 17 1 0.059 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0030162 Not Cancer Driver No 25 0.079 124 6 0.048 12
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0030162 Not Cancer Driver No 23 0.085 0 0 0.0 0
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0030162 Not Cancer Driver No 109 0.144 373 53 0.142 1
ASTL ASTL Q6HA08 Astacin-like metalloendopeptidase chr2 GO:0030162 Not Cancer Driver No 101 0.234 179 44 0.246 0
ATP13A2 ATP13A2 Q9NQ11 Polyamine-transporting ATPase 13A2 chr1 GO:0030162 Not Cancer Driver No 152 0.129 121 10 0.083 9
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0030162 Not Cancer Driver No 46 0.127 181 24 0.133 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0030162 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG2 BAG2 O95816 BAG family molecular chaperone regulator 2 chr6 GO:0030162 Not Cancer Driver No 17 0.081 112 9 0.08 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0030162 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0030162 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0030162 Census Yes 30 0.156 39 2 0.051 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0030162 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 GO:0030162 Census, Compendium Yes 40 0.12 132 10 0.076 0
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0030162 Not Cancer Driver No 65 0.11 456 42 0.092 5
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0030162 Not Cancer Driver No 7 0.033 0 0 0.0 0
C2CD3 C2CD3 Q4AC94 C2 domain-containing protein 3 chr11 GO:0030162 Not Cancer Driver No 249 0.106 1104 106 0.096 1
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0030162 Not Cancer Driver No 28 0.078 234 18 0.077 0
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0030162 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD18 CARD18 P57730 Caspase recruitment domain-containing protein 18 chr11 GO:0030162 Not Cancer Driver No 24 0.267 14 1 0.071 0
CARD8_ENST00000519940 CARD8 Q9Y2G2 Caspase recruitment domain-containing protein 8 chr19 GO:0030162 Not Cancer Driver No 53 0.099 126 7 0.056 1
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0030162 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0030162 Census Yes 49 0.118 71 7 0.099 0
CAST_ENST00000395813 CAST P20810 Calpastatin chr5 GO:0030162 Not Cancer Driver No 73 0.103 708 73 0.103 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0030162 Not Cancer Driver No 30 0.169 2 0 0.0 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0030162 Not Cancer Driver No 92 0.227 227 58 0.256 5
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0030162 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0030162 Not Cancer Driver No 99 0.191 152 24 0.158 0
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0030162 Not Cancer Driver No 24 0.081 0 0 0.0 0
CHAC1_ENST00000617961 CHAC1 Q9BUX1 Glutathione-specific gamma-glutamylcyclotransferase 1 chr15 GO:0030162 Not Cancer Driver No 30 0.135 49 5 0.102 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0030162 Not Cancer Driver No 19 0.087 23 1 0.043 0
CLDN3 CLDN3 O15551 Claudin-3 chr7 GO:0030162 Not Cancer Driver No 12 0.055 0 0 0.0 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0030162 Not Cancer Driver No 40 0.191 0 0 0.0 0
CLEC3B CLEC3B P05452 Tetranectin chr3 GO:0030162 Not Cancer Driver No 34 0.168 50 13 0.26 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0030162 Not Cancer Driver No 58 0.132 69 10 0.145 9
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0030162 Not Cancer Driver No 155 0.149 370 61 0.165 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0030162 Not Cancer Driver No 59 0.139 2 0 0.0 0
CR1_ENST00000367053 CR1 P17927 Complement receptor type 1 chr1 GO:0030162 Compendium Yes 383 0.188 151 42 0.278 0
CSN2 CSN2 P05814 Beta-casein chr4 GO:0030162 Not Cancer Driver No 49 0.217 41 12 0.293 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0030162 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0030162 Not Cancer Driver No 43 0.123 13 1 0.077 0
CST7 CST7 O76096 Cystatin-F chr20 GO:0030162 Not Cancer Driver No 12 0.083 15 2 0.133 0
CTSZ CTSZ Q9UBR2 Cathepsin Z chr20 GO:0030162 Not Cancer Driver No 30 0.099 10 0 0.0 0
CYCS_ENST00000409409 CYCS P99999 Cytochrome c chr7 GO:0030162 Not Cancer Driver No 12 0.114 19 3 0.158 1
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0030162 Not Cancer Driver No 211 0.165 86 11 0.128 3
DDRGK1 DDRGK1 Q96HY6 DDRGK domain-containing protein 1 chr20 GO:0030162 Not Cancer Driver No 34 0.108 181 23 0.127 0
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0030162 Not Cancer Driver No 62 0.259 54 8 0.148 1
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0030162 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA3 EFNA3 P52797 Ephrin-A3 chr1 GO:0030162 Not Cancer Driver No 24 0.101 31 11 0.355 0
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0030162 Not Cancer Driver No 51 0.118 21 2 0.095 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0030162 Not Cancer Driver No 182 0.185 140 24 0.171 0
F12 F12 P00748 Coagulation factor XII chr5 GO:0030162 Not Cancer Driver No 53 0.086 104 9 0.087 13
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0030162 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0030162 Census, Compendium Yes 55 0.164 62 18 0.29 22
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0030162 Not Cancer Driver No 68 0.114 120 4 0.033 0
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0030162 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0030162 Not Cancer Driver No 74 0.149 184 30 0.163 0
GAS1 GAS1 P54826 Growth arrest-specific protein 1 chr9 GO:0030162 Not Cancer Driver No 13 0.038 82 4 0.049 0
GLG1_ENST00000422840 GLG1 Q92896 Golgi apparatus protein 1 chr16 GO:0030162 Not Cancer Driver No 134 0.114 103 7 0.068 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0030162 Not Cancer Driver No 153 0.182 36 9 0.25 0
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0030162 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRN GRN P28799 Progranulin chr17 GO:0030162 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSAP GSAP A4D1B5 Gamma-secretase-activating protein chr7 GO:0030162 Not Cancer Driver No 89 0.104 13 0 0.0 0
GSN GSN P06396 Gelsolin chr9 GO:0030162 Not Cancer Driver No 76 0.097 316 28 0.089 2
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0030162 Census Yes 38 0.097 248 17 0.069 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0030162 Not Cancer Driver No 55 0.158 27 2 0.074 11
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0030162 Not Cancer Driver No 154 0.129 686 96 0.14 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0030162 Not Cancer Driver No 60 0.144 12 0 0.0 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0030162 Compendium Yes 44 0.096 127 9 0.071 2
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0030162 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0030162 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFT52_ENST00000373039 IFT52 Q9Y366 Intraflagellar transport protein 52 homolog chr20 GO:0030162 Not Cancer Driver No 60 0.137 56 7 0.125 1
IL10 IL10 P22301 Interleukin-10 chr1 GO:0030162 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0030162 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R2_ENST00000393414 IL1R2 P27930 Interleukin-1 receptor type 2 chr2 GO:0030162 Not Cancer Driver No 75 0.188 32 10 0.312 0
IL9 IL9 P15248 Interleukin-9 chr5 GO:0030162 Not Cancer Driver No 12 0.083 4 0 0.0 0
INPP5B_ENST00000373026 INPP5B P32019 Type II inositol 1,4,5-trisphosphate 5-phosphatase chr1 GO:0030162 Not Cancer Driver No 108 0.109 114 11 0.096 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0030162 Not Cancer Driver No 95 0.105 335 42 0.125 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0030162 Census, Compendium Yes 136 0.12 59 5 0.085 5
KLKB1 KLKB1 P03952 Plasma kallikrein chr4 GO:0030162 Not Cancer Driver No 117 0.183 24 1 0.042 3
LDLRAD3 LDLRAD3 Q86YD5 Low-density lipoprotein receptor class A domain-containing protein 3 chr11 GO:0030162 Not Cancer Driver No 46 0.133 123 14 0.114 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0030162 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0030162 Not Cancer Driver No 57 0.132 112 19 0.17 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0030162 Not Cancer Driver No 54 0.111 1 0 0.0 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0030162 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0030162 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0030162 Not Cancer Driver No 519 0.205 90 17 0.189 23
LTF LTF P02788 Lactotransferrin chr3 GO:0030162 Not Cancer Driver No 131 0.185 21 4 0.19 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0030162 Census Yes 95 0.186 84 12 0.143 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0030162 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0030162 Not Cancer Driver No 59 0.139 90 8 0.089 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0030162 Not Cancer Driver No 52 0.171 304 52 0.171 0
MELTF MELTF P08582 Melanotransferrin chr3 GO:0030162 Not Cancer Driver No 106 0.144 23 6 0.261 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0030162 Not Cancer Driver No 45 0.108 145 16 0.11 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0030162 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0030162 Not Cancer Driver No 129 0.182 124 26 0.21 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0030162 Not Cancer Driver No 7 0.103 0 0 0.0 0
MYH9 MYH9 P35579 Myosin-9 chr22 GO:0030162 Census, Compendium Yes 310 0.158 1120 160 0.143 17
NEDD8 NEDD8 Q15843 NEDD8 chr14 GO:0030162 Not Cancer Driver No 10 0.123 36 5 0.139 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0030162 Census, Compendium Yes 228 0.377 402 62 0.154 4
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0030162 Not Cancer Driver No 64 0.142 451 64 0.142 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0030162 Not Cancer Driver No 60 0.124 21 3 0.143 0
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0030162 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP6 NLRP6 P59044 NACHT, LRR and PYD domains-containing protein 6 chr11 GO:0030162 Not Cancer Driver No 106 0.119 203 28 0.138 0
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0030162 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0030162 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0030162 Not Cancer Driver No 59 0.123 391 41 0.105 0
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0030162 Not Cancer Driver No 162 0.141 253 34 0.134 0
OTUD4_ENST00000447906 OTUD4 Q01804 OTU domain-containing protein 4 chr4 GO:0030162 Not Cancer Driver No 148 0.133 788 120 0.152 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0030162 Not Cancer Driver No 52 0.123 290 31 0.107 0
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0030162 Compendium Yes 89 0.17 242 49 0.202 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0030162 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0030162 Not Cancer Driver No 49 0.129 28 5 0.179 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0030162 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0030162 Not Cancer Driver No 48 0.201 73 13 0.178 0
PERP PERP Q96FX8 p53 apoptosis effector related to PMP-22 chr6 GO:0030162 Not Cancer Driver No 28 0.145 0 0 0.0 1
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0030162 Census Yes 89 0.137 320 42 0.131 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0030162 Not Cancer Driver No 30 0.103 157 13 0.083 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0030162 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLGRKT PLGRKT Q9HBL7 Plasminogen receptor (KT) chr9 GO:0030162 Not Cancer Driver No 17 0.116 0 0 0.0 0
PLK1 PLK1 P53350 Serine/threonine-protein kinase PLK1 chr16 GO:0030162 Not Cancer Driver No 87 0.144 119 13 0.109 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0030162 Not Cancer Driver No 75 0.116 202 15 0.074 0
PML PML P29590 Protein PML chr15 GO:0030162 Census, Compendium Yes 112 0.127 312 34 0.109 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0030162 Census Yes 53 0.151 24 0 0.0 2
PRKACB_ENST00000370689 PRKACB P22694 cAMP-dependent protein kinase catalytic subunit beta chr1 GO:0030162 Not Cancer Driver No 50 0.142 26 6 0.231 4
PRNP PRNP P04156 Major prion protein chr20 GO:0030162 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRR7_ENST00000502922 PRR7 Q8TB68 Proline-rich protein 7 chr5 GO:0030162 Not Cancer Driver No 10 0.036 199 6 0.03 0
PRSS37_ENST00000438520 PRSS37 A4D1T9 Probable inactive serine protease 37 chr7 GO:0030162 Not Cancer Driver No 47 0.2 29 8 0.276 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0030162 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0030162 Not Cancer Driver No 139 0.152 214 28 0.131 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0030162 Not Cancer Driver No 16 0.082 39 4 0.103 0
QRICH2 QRICH2 Q9H0J4 Glutamine-rich protein 2 chr17 GO:0030162 Not Cancer Driver No 204 0.123 1369 171 0.125 0
RECK RECK O95980 Reversion-inducing cysteine-rich protein with Kazal motifs chr9 GO:0030162 Not Cancer Driver No 115 0.118 9 2 0.222 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0030162 Not Cancer Driver No 50 0.138 150 21 0.14 0
RFPL1 RFPL1 O75677 Ret finger protein-like 1 chr22 GO:0030162 Not Cancer Driver No 73 0.23 28 5 0.179 0
RFX4_ENST00000392842 RFX4 Q33E94 Transcription factor RFX4 chr12 GO:0030162 Not Cancer Driver No 124 0.169 308 47 0.153 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0030162 Not Cancer Driver No 63 0.14 105 13 0.124 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0030162 Not Cancer Driver No 38 0.121 69 9 0.13 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0030162 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF139 RNF139 Q8WU17 E3 ubiquitin-protein ligase RNF139 chr8 GO:0030162 Not Cancer Driver No 76 0.114 68 4 0.059 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0030162 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0030162 Not Cancer Driver No 30 0.081 112 7 0.062 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0030162 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0030162 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0030162 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0030162 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPL11 RPL11 P62913 60S ribosomal protein L11 chr1 GO:0030162 Not Cancer Driver No 27 0.152 12 1 0.083 1
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0030162 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL5_ENST00000370321 RPL5 P46777 60S ribosomal protein L5 chr1 GO:0030162 Census Yes 57 0.192 96 17 0.177 2
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0030162 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0030162 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0030162 Not Cancer Driver No 29 0.149 39 7 0.179 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0030162 Census, Compendium Yes 81 0.179 360 58 0.161 2
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0030162 Not Cancer Driver No 11 0.113 3 1 0.333 0
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0030162 Not Cancer Driver No 101 0.105 404 45 0.111 0
SEMG1 SEMG1 P04279 Semenogelin-1 chr20 GO:0030162 Not Cancer Driver No 101 0.219 442 98 0.222 0
SEMG2 SEMG2 Q02383 Semenogelin-2 chr20 GO:0030162 Not Cancer Driver No 147 0.253 561 145 0.258 0
SERPINB13_ENST00000344731 SERPINB13 Q9UIV8 Serpin B13 chr18 GO:0030162 Not Cancer Driver No 84 0.215 55 16 0.291 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0030162 Not Cancer Driver No 120 0.308 48 18 0.375 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0030162 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0030162 Not Cancer Driver No 62 0.156 0 0 0.0 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0030162 Not Cancer Driver No 62 0.126 112 21 0.188 1
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0030162 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0030162 Not Cancer Driver No 86 0.109 526 52 0.099 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0030162 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0030162 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0030162 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0030162 Not Cancer Driver No 33 0.093 164 12 0.073 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0030162 Census, Compendium Yes 97 0.228 111 19 0.171 5
SNX12 SNX12 Q9UMY4 Sorting nexin-12 chrX GO:0030162 Not Cancer Driver No 22 0.136 28 4 0.143 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0030162 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0030162 Not Cancer Driver No 71 0.119 231 23 0.1 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0030162 Not Cancer Driver No 374 0.169 87 10 0.115 0
SPINK1 SPINK1 P00995 Serine protease inhibitor Kazal-type 1 chr5 GO:0030162 Not Cancer Driver No 14 0.177 0 0 0.0 3
SPINK2_ENST00000248701 SPINK2 P20155 Serine protease inhibitor Kazal-type 2 chr4 GO:0030162 Not Cancer Driver No 10 0.119 0 0 0.0 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0030162 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPINK6_ENST00000621437 SPINK6 Q6UWN8 Serine protease inhibitor Kazal-type 6 chr5 GO:0030162 Not Cancer Driver No 17 0.212 0 0 0.0 0
SPON1 SPON1 Q9HCB6 Spondin-1 chr11 GO:0030162 Not Cancer Driver No 120 0.149 191 30 0.157 0
SPOP SPOP O43791 Speckle-type POZ protein chr17 GO:0030162 Census, Compendium Yes 147 0.393 25 5 0.2 6
SPOPL SPOPL Q6IQ16 Speckle-type POZ protein-like chr2 GO:0030162 Not Cancer Driver No 87 0.222 40 14 0.35 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0030162 Census Yes 53 0.099 130 11 0.085 1
ST18 ST18 O60284 Suppression of tumorigenicity 18 protein chr8 GO:0030162 Not Cancer Driver No 330 0.315 820 282 0.344 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0030162 Census, Compendium Yes 110 0.143 152 15 0.099 19
STYX STYX Q8WUJ0 Serine/threonine/tyrosine-interacting protein chr14 GO:0030162 Not Cancer Driver No 20 0.09 30 2 0.067 0
SUFU SUFU Q9UMX1 Suppressor of fused homolog chr10 GO:0030162 Census Yes 55 0.114 199 19 0.095 2
SVBP_ENST00000372522 SVBP Q8N300 Small vasohibin-binding protein chr1 GO:0030162 Not Cancer Driver No 7 0.106 66 7 0.106 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0030162 Not Cancer Driver No 16 0.208 77 16 0.208 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0030162 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0030162 Not Cancer Driver No 42 0.099 302 26 0.086 0
TBC1D10A_ENST00000215790 TBC1D10A Q9BXI6 TBC1 domain family member 10A chr22 GO:0030162 Not Cancer Driver No 72 0.142 209 26 0.124 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0030162 Compendium Yes 61 0.18 285 52 0.182 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0030162 Not Cancer Driver No 188 0.161 320 58 0.181 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0030162 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0030162 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0030162 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0030162 Not Cancer Driver No 30 0.134 8 2 0.25 0
TMED10 TMED10 P49755 Transmembrane emp24 domain-containing protein 10 chr14 GO:0030162 Not Cancer Driver No 24 0.11 15 3 0.2 0
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0030162 Not Cancer Driver No 40 0.065 188 9 0.048 0
TMEM59 TMEM59 Q9BXS4 Transmembrane protein 59 chr1 GO:0030162 Not Cancer Driver No 39 0.121 26 3 0.115 0
TMEM98 TMEM98 Q9Y2Y6 Transmembrane protein 98 chr17 GO:0030162 Not Cancer Driver No 39 0.173 27 3 0.111 2
TNF TNF P01375 Tumor necrosis factor chr6 GO:0030162 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0030162 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0030162 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0030162 Not Cancer Driver No 21 0.382 55 21 0.382 0
TNP2 TNP2 Q05952 Nuclear transition protein 2 chr16 GO:0030162 Not Cancer Driver No 23 0.167 138 23 0.167 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0030162 Compendium Yes 61 0.107 101 9 0.089 1
TRIM21 TRIM21 P19474 E3 ubiquitin-protein ligase TRIM21 chr11 GO:0030162 Not Cancer Driver No 85 0.179 49 7 0.143 0
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:0030162 Not Cancer Driver No 74 0.143 62 8 0.129 0
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0030162 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0030162 Not Cancer Driver No 82 0.131 581 79 0.136 8
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0030162 Not Cancer Driver No 35 0.118 271 33 0.122 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0030162 Not Cancer Driver No 121 0.14 224 42 0.188 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0030162 Not Cancer Driver No 59 0.119 86 6 0.07 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0030162 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP19_ENST00000398888 USP19 O94966 Ubiquitin carboxyl-terminal hydrolase 19 chr3 GO:0030162 Not Cancer Driver No 161 0.122 539 68 0.126 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0030162 Not Cancer Driver No 135 0.128 354 55 0.155 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0030162 Not Cancer Driver No 88 0.109 186 16 0.086 16
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0030162 Not Cancer Driver No 61 0.09 125 19 0.152 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0030162 Not Cancer Driver No 29 0.078 25 0 0.0 8
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0030162 Not Cancer Driver No 89 0.179 55 6 0.109 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0030162 Not Cancer Driver No 90 0.15 396 44 0.111 0