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Total number of protein in "GO:0019899" GO term:  768

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0019899 Not Cancer Driver No 260 0.176 144 22 0.153 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0019899 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0019899 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0019899 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0019899 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC011195.2 IGBP1P2 A0A1W2PR95 HCG1642624, isoform CRA_a chr17 GO:0019899 Not Cancer Driver No 6 0.018 201 4 0.02 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0019899 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0019899 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0019899 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACIN1 ACIN1 Q9UKV3 Apoptotic chromatin condensation inducer in the nucleus chr14 GO:0019899 Not Cancer Driver No 157 0.117 1294 155 0.12 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0019899 Not Cancer Driver No 112 0.299 43 5 0.116 5
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0019899 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY10 ADCY10 Q96PN6 Adenylate cyclase type 10 chr1 GO:0019899 Not Cancer Driver No 249 0.155 24 4 0.167 0
ADCY2 ADCY2 Q08462 Adenylate cyclase type 2 chr5 GO:0019899 Not Cancer Driver No 303 0.278 95 24 0.253 0
ADCY4_ENST00000554068 ADCY4 Q8NFM4 Adenylate cyclase type 4 chr14 GO:0019899 Not Cancer Driver No 137 0.127 94 23 0.245 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0019899 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0019899 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0019899 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0019899 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0019899 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0019899 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0019899 Not Cancer Driver No 52 0.126 35 4 0.114 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0019899 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0019899 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0019899 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP8L AKAP8L Q9ULX6 A-kinase anchor protein 8-like chr19 GO:0019899 Not Cancer Driver No 76 0.118 510 61 0.12 0
AKIRIN2 AKIRIN2 Q53H80 Akirin-2 chr6 GO:0019899 Not Cancer Driver No 21 0.103 119 11 0.092 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0019899 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALDOB ALDOB P05062 Fructose-bisphosphate aldolase B chr9 GO:0019899 Not Cancer Driver No 91 0.25 34 11 0.324 16
ALOX5AP_ENST00000380490 ALOX5AP P20292 Arachidonate 5-lipoxygenase-activating protein chr13 GO:0019899 Not Cancer Driver No 17 0.106 1 0 0.0 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0019899 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANK1_ENST00000347528 ANK1 P16157 Ankyrin-1 chr8 GO:0019899 Census Yes 405 0.215 810 171 0.211 3
ANK2 ANK2 Q01484 Ankyrin-2 chr4 GO:0019899 Not Cancer Driver No 770 0.195 2844 566 0.199 4
ANKIB1 ANKIB1 Q9P2G1 Ankyrin repeat and IBR domain-containing protein 1 chr7 GO:0019899 Not Cancer Driver No 141 0.129 577 78 0.135 0
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0019899 Not Cancer Driver No 127 0.135 521 71 0.136 2
ANKMY2 ANKMY2 Q8IV38 Ankyrin repeat and MYND domain-containing protein 2 chr7 GO:0019899 Not Cancer Driver No 57 0.129 99 15 0.152 0
ANKRD2 ANKRD2 Q9GZV1 Ankyrin repeat domain-containing protein 2 chr10 GO:0019899 Not Cancer Driver No 34 0.094 192 18 0.094 0
APBA3 APBA3 O96018 Amyloid-beta A4 precursor protein-binding family A member 3 chr19 GO:0019899 Not Cancer Driver No 55 0.096 306 43 0.141 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0019899 Not Cancer Driver No 32 0.121 0 0 0.0 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0019899 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0019899 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0019899 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0019899 Not Cancer Driver No 8 0.079 14 2 0.143 1
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0019899 Not Cancer Driver No 128 0.166 418 71 0.17 17
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0019899 Not Cancer Driver No 67 0.094 292 31 0.106 1
AR AR P10275 Androgen receptor chrX GO:0019899 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0019899 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0019899 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARIH1 ARIH1 Q9Y4X5 E3 ubiquitin-protein ligase ARIH1 chr15 GO:0019899 Not Cancer Driver No 46 0.083 119 7 0.059 0
ARIH2 ARIH2 O95376 E3 ubiquitin-protein ligase ARIH2 chr3 GO:0019899 Not Cancer Driver No 64 0.13 85 11 0.129 0
ARMT1 ARMT1 Q9H993 Damage-control phosphatase ARMT1 chr6 GO:0019899 Not Cancer Driver No 53 0.12 1 0 0.0 0
ARPC4_ENST00000397261 ARPC4 P59998 Actin-related protein 2/3 complex subunit 4 chr3 GO:0019899 Not Cancer Driver No 11 0.065 3 0 0.0 0
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0019899 Not Cancer Driver No 17 0.152 112 17 0.152 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0019899 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATF7_ENST00000456903 ATF7 P17544 Cyclic AMP-dependent transcription factor ATF-7 chr12 GO:0019899 Not Cancer Driver No 45 0.093 468 45 0.096 0
ATG3 ATG3 Q9NT62 Ubiquitin-like-conjugating enzyme ATG3 chr3 GO:0019899 Not Cancer Driver No 29 0.092 110 9 0.082 0
ATP1B1 ATP1B1 P05026 Sodium/potassium-transporting ATPase subunit beta-1 chr1 GO:0019899 Not Cancer Driver No 38 0.125 55 9 0.164 0
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0019899 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP1B3 ATP1B3 P54709 Sodium/potassium-transporting ATPase subunit beta-3 chr3 GO:0019899 Not Cancer Driver No 36 0.129 6 1 0.167 0
ATP2A2 ATP2A2 P16615 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 chr12 GO:0019899 Not Cancer Driver No 136 0.131 78 14 0.179 41
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0019899 Not Cancer Driver No 8 0.075 85 7 0.082 0
ATP6V0A1_ENST00000343619 ATP6V0A1 Q93050 V-type proton ATPase 116 kDa subunit a 1 chr17 GO:0019899 Not Cancer Driver No 98 0.117 85 14 0.165 0
ATP6V0A2 ATP6V0A2 Q9Y487 V-type proton ATPase 116 kDa subunit a 2 chr12 GO:0019899 Not Cancer Driver No 88 0.103 36 6 0.167 0
ATP6V0A4 ATP6V0A4 Q9HBG4 V-type proton ATPase 116 kDa subunit a 4 chr7 GO:0019899 Not Cancer Driver No 148 0.176 43 6 0.14 6
ATP6V1E1 ATP6V1E1 P36543 V-type proton ATPase subunit E 1 chr22 GO:0019899 Not Cancer Driver No 27 0.119 27 3 0.111 2
ATP6V1G1 ATP6V1G1 O75348 V-type proton ATPase subunit G 1 chr9 GO:0019899 Not Cancer Driver No 12 0.102 91 8 0.088 0
ATP6V1G3_ENST00000367382 ATP6V1G3 Q96LB4 V-type proton ATPase subunit G 3 chr1 GO:0019899 Not Cancer Driver No 37 0.314 98 27 0.276 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0019899 Not Cancer Driver No 46 0.127 181 24 0.133 0
AUP1 AUP1 Q9Y679 Lipid droplet-regulating VLDL assembly factor AUP1 chr2 GO:0019899 Not Cancer Driver No 41 0.1 122 13 0.107 0
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0019899 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0019899 Not Cancer Driver No 83 0.196 51 5 0.098 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0019899 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0019899 Census, Compendium Yes 114 0.135 547 77 0.141 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0019899 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0019899 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0019899 Not Cancer Driver No 98 0.087 861 79 0.092 0
BANF1_ENST00000445560 BANF1 O75531 Barrier-to-autointegration factor chr11 GO:0019899 Not Cancer Driver No 10 0.112 11 2 0.182 1
BANK1 BANK1 Q8NDB2 B-cell scaffold protein with ankyrin repeats chr4 GO:0019899 Not Cancer Driver No 150 0.191 394 73 0.185 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0019899 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0019899 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0019899 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0019899 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 GO:0019899 Not Cancer Driver No 10 0.049 34 1 0.029 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0019899 Census, Compendium Yes 24 0.1 72 5 0.069 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0019899 Not Cancer Driver No 56 0.124 30 1 0.033 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0019899 Not Cancer Driver No 20 0.141 49 6 0.122 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0019899 Not Cancer Driver No 52 0.174 136 22 0.162 0
BLNK BLNK Q8WV28 B-cell linker protein chr10 GO:0019899 Not Cancer Driver No 74 0.162 376 61 0.162 0
BLZF1 BLZF1 Q9H2G9 Golgin-45 chr1 GO:0019899 Not Cancer Driver No 51 0.128 218 24 0.11 0
BOD1 BOD1 Q96IK1 Biorientation of chromosomes in cell division protein 1 chr5 GO:0019899 Not Cancer Driver No 16 0.086 133 10 0.075 0
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0019899 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BOD1L2 BOD1L2 Q8IYS8 Biorientation of chromosomes in cell division protein 1-like 2 chr18 GO:0019899 Not Cancer Driver No 29 0.169 144 26 0.181 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0019899 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0019899 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0019899 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTG1 BTG1 P62324 Protein BTG1 chr12 GO:0019899 Census, Compendium Yes 21 0.123 19 0 0.0 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0019899 Census, Compendium Yes 147 0.223 114 27 0.237 110
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0019899 Not Cancer Driver No 14 0.05 103 6 0.058 2
CAD CAD P27708 CAD protein chr2 GO:0019899 Not Cancer Driver No 287 0.129 368 52 0.141 1
CALM1 CALM1 P0DP23 Calmodulin-1 chr14 GO:0019899 Not Cancer Driver No 19 0.128 115 15 0.13 7
CALM2 CALM2 P0DP24 Calmodulin-2 chr2 GO:0019899 Not Cancer Driver No 18 0.121 115 13 0.113 8
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0019899 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAP1_ENST00000372805 CAP1 Q01518 Adenylyl cyclase-associated protein 1 chr1 GO:0019899 Not Cancer Driver No 70 0.147 156 31 0.199 0
CAP2 CAP2 P40123 Adenylyl cyclase-associated protein 2 chr6 GO:0019899 Not Cancer Driver No 81 0.17 171 28 0.164 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0019899 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0019899 Not Cancer Driver No 36 0.183 23 7 0.304 0
CARD17 CARD17 Q5XLA6 Caspase recruitment domain-containing protein 17 chr11 GO:0019899 Not Cancer Driver No 24 0.218 22 7 0.318 0
CARD18 CARD18 P57730 Caspase recruitment domain-containing protein 18 chr11 GO:0019899 Not Cancer Driver No 24 0.267 14 1 0.071 0
CASC3 CASC3 O15234 Protein CASC3 chr17 GO:0019899 Not Cancer Driver No 84 0.119 700 83 0.119 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0019899 Not Cancer Driver No 63 0.139 42 12 0.286 0
CAT CAT P04040 Catalase chr11 GO:0019899 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0019899 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0019899 Not Cancer Driver No 27 0.179 0 0 0.0 25
CAVIN2 CAVIN2 O95810 Caveolae-associated protein 2 chr2 GO:0019899 Not Cancer Driver No 109 0.256 393 99 0.252 0
CAVIN3 CAVIN3 Q969G5 Caveolae-associated protein 3 chr11 GO:0019899 Not Cancer Driver No 22 0.084 234 19 0.081 0
CBS_ENST00000359624 CBS P35520 Cystathionine beta-synthase chr21 GO:0019899 Not Cancer Driver No 61 0.111 160 19 0.119 103
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 GO:0019899 Not Cancer Driver No 31 0.168 154 25 0.162 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0019899 Not Cancer Driver No 23 0.126 119 18 0.151 0
CBX4 CBX4 O00257 E3 SUMO-protein ligase CBX4 chr17 GO:0019899 Not Cancer Driver No 72 0.129 477 63 0.132 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0019899 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0019899 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0019899 Census, Compendium Yes 55 0.186 31 25 0.806 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0019899 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0019899 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0019899 Census Yes 31 0.105 185 20 0.108 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0019899 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0019899 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDK2AP1 CDK2AP1 O14519 Cyclin-dependent kinase 2-associated protein 1 chr12 GO:0019899 Not Cancer Driver No 10 0.087 76 8 0.105 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0019899 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0019899 Not Cancer Driver No 60 0.11 377 35 0.093 5
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0019899 Not Cancer Driver No 3 0.009 276 2 0.007 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0019899 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0019899 Not Cancer Driver No 25 0.113 137 13 0.095 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0019899 Not Cancer Driver No 24 0.108 204 23 0.113 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0019899 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLEC6A CLEC6A Q6EIG7 C-type lectin domain family 6 member A chr12 GO:0019899 Not Cancer Driver No 41 0.196 7 0 0.0 0
CLPP CLPP Q16740 ATP-dependent Clp protease proteolytic subunit, mitochondrial chr19 GO:0019899 Not Cancer Driver No 22 0.079 83 9 0.108 3
CLTC_ENST00000269122 CLTC Q00610 Clathrin heavy chain 1 chr17 GO:0019899 Census, Compendium Yes 190 0.113 71 6 0.085 1
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0019899 Census Yes 570 0.428 161 82 0.509 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0019899 Not Cancer Driver No 36 0.108 32 7 0.219 0
COTL1 COTL1 Q14019 Coactosin-like protein chr16 GO:0019899 Not Cancer Driver No 17 0.12 7 2 0.286 0
CPSF1 CPSF1 Q10570 Cleavage and polyadenylation specificity factor subunit 1 chr8 GO:0019899 Not Cancer Driver No 177 0.123 298 42 0.141 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0019899 Census Yes 25 0.076 277 23 0.083 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0019899 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0019899 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0019899 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 GO:0019899 Not Cancer Driver No 72 0.128 158 24 0.152 0
CTSG CTSG P08311 Cathepsin G chr14 GO:0019899 Not Cancer Driver No 65 0.255 80 29 0.362 0
CTTNBP2NL CTTNBP2NL Q9P2B4 CTTNBP2 N-terminal-like protein chr1 GO:0019899 Not Cancer Driver No 82 0.128 559 78 0.14 0
CUTA_ENST00000488034 CUTA O60888 Protein CutA chr6 GO:0019899 Not Cancer Driver No 16 0.089 15 3 0.2 0
CYB5A CYB5A P00167 Cytochrome b5 chr18 GO:0019899 Not Cancer Driver No 20 0.149 70 12 0.171 1
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0019899 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0019899 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP2A6 CYP2A6 P11509 Cytochrome P450 2A6 chr19 GO:0019899 Not Cancer Driver No 107 0.217 40 10 0.25 0
CYP2C19 CYP2C19 P33261 Cytochrome P450 2C19 chr10 GO:0019899 Not Cancer Driver No 157 0.32 32 12 0.375 0
CYP2E1_ENST00000252945 CYP2E1 P05181 Cytochrome P450 2E1 chr10 GO:0019899 Not Cancer Driver No 87 0.176 21 6 0.286 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0019899 Not Cancer Driver No 91 0.181 22 2 0.091 1
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0019899 Not Cancer Driver No 131 0.11 681 68 0.1 0
DACT1 DACT1 Q9NYF0 Dapper homolog 1 chr14 GO:0019899 Not Cancer Driver No 163 0.195 598 127 0.212 1
DACT2 DACT2 Q5SW24 Dapper homolog 2 chr6 GO:0019899 Not Cancer Driver No 35 0.045 655 30 0.046 0
DACT3 DACT3 Q96B18 Dapper homolog 3 chr19 GO:0019899 Not Cancer Driver No 17 0.027 549 12 0.022 0
DAOA_ENST00000375936 DAOA P59103 D-amino acid oxidase activator chr13 GO:0019899 Not Cancer Driver No 45 0.294 53 20 0.377 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0019899 Census, Compendium Yes 106 0.143 549 81 0.148 0
DAZAP2_ENST00000412716 DAZAP2 Q15038 DAZ-associated protein 2 chr12 GO:0019899 Not Cancer Driver No 17 0.101 68 7 0.103 0
DCUN1D1 DCUN1D1 Q96GG9 DCN1-like protein 1 chr3 GO:0019899 Not Cancer Driver No 34 0.131 13 0 0.0 0
DCUN1D2 DCUN1D2 Q6PH85 DCN1-like protein 2 chr13 GO:0019899 Not Cancer Driver No 36 0.139 29 7 0.241 0
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0019899 Not Cancer Driver No 36 0.118 118 9 0.076 0
DCUN1D4_ENST00000334635 DCUN1D4 Q92564 DCN1-like protein 4 chr4 GO:0019899 Not Cancer Driver No 51 0.175 57 12 0.211 0
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0019899 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0019899 Not Cancer Driver No 98 0.204 5 0 0.0 9
DERL1 DERL1 Q9BUN8 Derlin-1 chr8 GO:0019899 Not Cancer Driver No 28 0.112 11 1 0.091 0
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0019899 Not Cancer Driver No 19 0.079 15 1 0.067 0
DERL3_ENST00000318109 DERL3 Q96Q80 Derlin-3 chr22 GO:0019899 Not Cancer Driver No 18 0.077 18 1 0.056 0
DFFB_ENST00000378209 DFFB O76075 DNA fragmentation factor subunit beta chr1 GO:0019899 Not Cancer Driver No 37 0.109 27 1 0.037 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0019899 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0019899 Not Cancer Driver No 55 0.107 0 0 0.0 6
DIRAS1_ENST00000585334 DIRAS1 O95057 GTP-binding protein Di-Ras1 chr19 GO:0019899 Not Cancer Driver No 38 0.192 32 5 0.156 0
DIS3L DIS3L Q8TF46 DIS3-like exonuclease 1 chr15 GO:0019899 Not Cancer Driver No 111 0.105 139 20 0.144 0
DIXDC1 DIXDC1 Q155Q3 Dixin chr11 GO:0019899 Not Cancer Driver No 72 0.105 495 55 0.111 0
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0019899 Not Cancer Driver No 120 0.133 460 67 0.146 0
DMBT1_ENST00000619379 DMBT1 Q9UGM3 Deleted in malignant brain tumors 1 protein chr10 GO:0019899 Not Cancer Driver No 506 0.21 404 64 0.158 0
DMD DMD P11532 Dystrophin chrX GO:0019899 Not Cancer Driver No 895 0.243 1399 329 0.235 14
DNAJB1 DNAJB1 P25685 DnaJ homolog subfamily B member 1 chr19 GO:0019899 Census, Compendium Yes 35 0.103 196 26 0.133 0
DNAJC10 DNAJC10 Q8IXB1 DnaJ homolog subfamily C member 10 chr2 GO:0019899 Not Cancer Driver No 110 0.139 36 3 0.083 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0019899 Census Yes 138 0.159 270 43 0.159 22
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 GO:0019899 Not Cancer Driver No 166 0.191 257 45 0.175 0
DNMT3L_ENST00000628202 DNMT3L Q9UJW3 DNA (cytosine-5)-methyltransferase 3-like chr21 GO:0019899 Not Cancer Driver No 83 0.215 10 1 0.1 0
DOK2 DOK2 O60496 Docking protein 2 chr8 GO:0019899 Not Cancer Driver No 58 0.141 254 31 0.122 0
DROSHA_ENST00000344624 DROSHA Q9NRR4 Ribonuclease 3 chr5 GO:0019899 Census, Compendium Yes 175 0.127 682 100 0.147 0
DSP DSP P15924 Desmoplakin chr6 GO:0019899 Not Cancer Driver No 483 0.168 1124 204 0.181 6
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0019899 Not Cancer Driver No 86 0.116 260 24 0.092 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 GO:0019899 Not Cancer Driver No 40 0.125 0 0 0.0 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0019899 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP10 DUSP10 Q9Y6W6 Dual specificity protein phosphatase 10 chr1 GO:0019899 Not Cancer Driver No 81 0.168 135 24 0.178 0
DUSP16 DUSP16 Q9BY84 Dual specificity protein phosphatase 16 chr12 GO:0019899 Compendium Yes 70 0.105 273 34 0.125 0
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0019899 Not Cancer Driver No 34 0.157 15 5 0.333 0
DUSP2 DUSP2 Q05923 Dual specificity protein phosphatase 2 chr2 GO:0019899 Not Cancer Driver No 24 0.076 23 3 0.13 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0019899 Not Cancer Driver No 73 0.105 434 38 0.088 0
DYM DYM Q7RTS9 Dymeclin chr18 GO:0019899 Not Cancer Driver No 78 0.117 21 0 0.0 3
ECD_ENST00000372979 ECD O95905 Protein ecdysoneless homolog chr10 GO:0019899 Not Cancer Driver No 68 0.106 254 26 0.102 0
ECM1_ENST00000369047 ECM1 Q16610 Extracellular matrix protein 1 chr1 GO:0019899 Not Cancer Driver No 91 0.169 219 28 0.128 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0019899 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGLN1 EGLN1 Q9GZT9 Egl nine homolog 1 chr1 GO:0019899 Not Cancer Driver No 35 0.082 206 8 0.039 2
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0019899 Not Cancer Driver No 78 0.144 501 72 0.144 0
EHHADH EHHADH Q08426 Peroxisomal bifunctional enzyme chr3 GO:0019899 Not Cancer Driver No 116 0.16 74 14 0.189 1
EID1 EID1 Q9Y6B2 EP300-interacting inhibitor of differentiation 1 chr15 GO:0019899 Not Cancer Driver No 22 0.118 159 17 0.107 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0019899 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0019899 Not Cancer Driver No 26 0.12 54 6 0.111 0
ENO2 ENO2 P09104 Gamma-enolase chr12 GO:0019899 Not Cancer Driver No 48 0.111 12 2 0.167 0
ENSA_ENST00000369014 ENSA O43768 Alpha-endosulfine chr1 GO:0019899 Not Cancer Driver No 15 0.124 121 15 0.124 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0019899 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0019899 Not Cancer Driver No 125 0.128 250 28 0.112 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0019899 Census, Compendium Yes 121 0.203 195 27 0.138 2
ESR2 ESR2 Q92731 Estrogen receptor beta chr14 GO:0019899 Not Cancer Driver No 90 0.17 92 11 0.12 1
ETV3 ETV3 P41162 ETS translocation variant 3 chr1 GO:0019899 Not Cancer Driver No 48 0.094 330 24 0.073 0
EZR EZR P15311 Ezrin chr6 GO:0019899 Census Yes 66 0.113 295 35 0.119 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0019899 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF2 FAF2 Q96CS3 FAS-associated factor 2 chr5 GO:0019899 Not Cancer Driver No 54 0.121 171 16 0.094 0
FAM83B FAM83B Q5T0W9 Protein FAM83B chr6 GO:0019899 Not Cancer Driver No 314 0.311 684 219 0.32 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0019899 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCI FANCI Q9NVI1 Fanconi anemia group I protein chr15 GO:0019899 Not Cancer Driver No 161 0.121 129 20 0.155 2
FBL FBL P22087 rRNA 2'-O-methyltransferase fibrillarin chr19 GO:0019899 Not Cancer Driver No 46 0.143 145 22 0.152 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0019899 Not Cancer Driver No 66 0.168 277 49 0.177 0
FLNA FLNA P21333 Filamin-A chrX GO:0019899 Census Yes 416 0.157 1456 214 0.147 28
FN1 FN1 P02751 Fibronectin chr2 GO:0019899 Compendium Yes 394 0.159 1243 185 0.149 8
FNIP1 FNIP1 Q8TF40 Folliculin-interacting protein 1 chr5 GO:0019899 Not Cancer Driver No 143 0.123 384 44 0.115 0
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0019899 Census, Compendium Yes 39 0.104 257 20 0.078 26
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0019899 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO4 FOXO4 P98177 Forkhead box protein O4 chrX GO:0019899 Census Yes 75 0.149 441 61 0.138 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0019899 Not Cancer Driver No 38 0.088 186 16 0.086 10
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0019899 Not Cancer Driver No 69 0.136 415 58 0.14 0
FRS3_ENST00000259748 FRS3 O43559 Fibroblast growth factor receptor substrate 3 chr6 GO:0019899 Not Cancer Driver No 77 0.157 388 58 0.149 0
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0019899 Not Cancer Driver No 92 0.171 70 13 0.186 0
GAB2 GAB2 Q9UQC2 GRB2-associated-binding protein 2 chr11 GO:0019899 Not Cancer Driver No 85 0.126 537 73 0.136 0
GABARAPL2 GABARAPL2 P60520 Gamma-aminobutyric acid receptor-associated protein-like 2 chr16 GO:0019899 Not Cancer Driver No 11 0.094 2 1 0.5 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0019899 Not Cancer Driver No 92 0.155 166 27 0.163 0
GCH1_ENST00000622544 GCH1 P30793 GTP cyclohydrolase 1 chr14 GO:0019899 Not Cancer Driver No 20 0.08 99 5 0.051 38
GCHFR GCHFR P30047 GTP cyclohydrolase 1 feedback regulatory protein chr15 GO:0019899 Not Cancer Driver No 9 0.107 20 0 0.0 0
GCKR GCKR Q14397 Glucokinase regulatory protein chr2 GO:0019899 Not Cancer Driver No 98 0.157 85 27 0.318 0
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0019899 Not Cancer Driver No 32 0.117 31 3 0.097 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0019899 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLRX3 GLRX3 O76003 Glutaredoxin-3 chr10 GO:0019899 Not Cancer Driver No 52 0.155 24 4 0.167 0
GNA12 GNA12 Q03113 Guanine nucleotide-binding protein subunit alpha-12 chr7 GO:0019899 Not Cancer Driver No 41 0.108 20 0 0.0 0
GOLGA7B GOLGA7B Q2TAP0 Golgin subfamily A member 7B chr10 GO:0019899 Not Cancer Driver No 22 0.132 24 0 0.0 0
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0019899 Not Cancer Driver No 41 0.138 72 1 0.014 0
GPIHBP1 GPIHBP1 Q8IV16 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 chr8 GO:0019899 Not Cancer Driver No 26 0.141 82 15 0.183 10
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0019899 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0019899 Not Cancer Driver No 308 0.276 179 22 0.123 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0019899 Not Cancer Driver No 77 0.131 103 18 0.175 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0019899 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0019899 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0019899 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTM1 GSTM1 P09488 Glutathione S-transferase Mu 1 chr1 GO:0019899 Not Cancer Driver No 17 0.078 7 1 0.143 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0019899 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTM3_ENST00000361066 GSTM3 P21266 Glutathione S-transferase Mu 3 chr1 GO:0019899 Not Cancer Driver No 32 0.142 0 0 0.0 0
GSTM4 GSTM4 Q03013 Glutathione S-transferase Mu 4 chr1 GO:0019899 Not Cancer Driver No 24 0.11 4 1 0.25 0
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0019899 Not Cancer Driver No 32 0.152 0 0 0.0 0
H2AFX H2AX P16104 Histone H2AX chr11 GO:0019899 Not Cancer Driver No 20 0.14 68 10 0.147 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0019899 Not Cancer Driver No 46 0.124 125 19 0.152 0
HACD2 HACD2 Q6Y1H2 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 chr3 GO:0019899 Not Cancer Driver No 16 0.063 14 0 0.0 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 GO:0019899 Not Cancer Driver No 28 0.077 10 0 0.0 0
HACD4 HACD4 Q5VWC8 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 chr9 GO:0019899 Not Cancer Driver No 30 0.129 0 0 0.0 0
HAND1 HAND1 O96004 Heart- and neural crest derivatives-expressed protein 1 chr5 GO:0019899 Not Cancer Driver No 35 0.163 166 29 0.175 0
HAUS7 HAUS7 Q99871 HAUS augmin-like complex subunit 7 chrX GO:0019899 Not Cancer Driver No 51 0.142 78 7 0.09 0
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0019899 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC10 HDAC10 Q969S8 Polyamine deacetylase HDAC10 chr22 GO:0019899 Not Cancer Driver No 67 0.1 121 11 0.091 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0019899 Not Cancer Driver No 46 0.094 145 14 0.097 0
HDAC3 HDAC3 O15379 Histone deacetylase 3 chr5 GO:0019899 Not Cancer Driver No 65 0.152 61 8 0.131 0
HDAC5_ENST00000586802 HDAC5 Q9UQL6 Histone deacetylase 5 chr17 GO:0019899 Not Cancer Driver No 118 0.105 718 73 0.102 0
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0019899 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDAC7_ENST00000427332 HDAC7 Q8WUI4 Histone deacetylase 7 chr12 GO:0019899 Not Cancer Driver No 91 0.096 570 50 0.088 0
HDAC9_ENST00000432645 HDAC9 Q9UKV0 Histone deacetylase 9 chr7 GO:0019899 Not Cancer Driver No 286 0.283 631 178 0.282 0
HDHD2 HDHD2 Q9H0R4 Haloacid dehalogenase-like hydrolase domain-containing protein 2 chr18 GO:0019899 Not Cancer Driver No 23 0.089 21 0 0.0 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0019899 Not Cancer Driver No 37 0.132 226 32 0.142 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0019899 Census Yes 118 0.143 435 51 0.117 0
HINFP HINFP Q9BQA5 Histone H4 transcription factor chr11 GO:0019899 Not Cancer Driver No 65 0.126 154 24 0.156 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0019899 Not Cancer Driver No 11 0.087 6 0 0.0 6
HIST1H2AG H2AC17 P0C0S8 Histone H2A type 1 chr6 GO:0019899 Not Cancer Driver No 41 0.315 58 23 0.397 0
HIST1H2AI H2AC17 P0C0S8 Histone H2A type 1 chr6 GO:0019899 Not Cancer Driver No 27 0.208 58 16 0.276 0
HIST1H2AK H2AC17 P0C0S8 Histone H2A type 1 chr6 GO:0019899 Not Cancer Driver No 42 0.323 58 20 0.345 0
HIST1H2AL H2AC17 P0C0S8 Histone H2A type 1 chr6 GO:0019899 Not Cancer Driver No 26 0.2 58 12 0.207 0
HIST1H2AM H2AC17 P0C0S8 Histone H2A type 1 chr6 GO:0019899 Not Cancer Driver No 25 0.192 58 16 0.276 0
HIST1H2BH H2BC9 Q93079 Histone H2B type 1-H chr6 GO:0019899 Not Cancer Driver No 42 0.333 79 20 0.253 0
HLCS HLCS P50747 Biotin--protein ligase chr21 GO:0019899 Not Cancer Driver No 95 0.131 158 15 0.095 23
HMGA1 HMGA1 P17096 High mobility group protein HMG-I/HMG-Y chr6 GO:0019899 Census Yes 6 0.056 107 6 0.056 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0019899 Not Cancer Driver No 25 0.116 203 20 0.099 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0019899 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0019899 Not Cancer Driver No 77 0.093 504 45 0.089 0
HNRNPUL1 HNRNPUL1 Q9BUJ2 Heterogeneous nuclear ribonucleoprotein U-like protein 1 chr19 GO:0019899 Not Cancer Driver No 100 0.117 535 49 0.092 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:0019899 Census Yes 46 0.169 187 35 0.187 0
HRC HRC P23327 Sarcoplasmic reticulum histidine-rich calcium-binding protein chr19 GO:0019899 Not Cancer Driver No 110 0.157 612 98 0.16 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0019899 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0019899 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0019899 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0019899 Not Cancer Driver No 15 0.023 200 5 0.025 0
HSPA2_ENST00000247207 HSPA2 P54652 Heat shock-related 70 kDa protein 2 chr14 GO:0019899 Not Cancer Driver No 93 0.146 286 38 0.133 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0019899 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPA6 HSPA6 P17066 Heat shock 70 kDa protein 6 chr1 GO:0019899 Not Cancer Driver No 112 0.174 235 27 0.115 0
HSPA8_ENST00000532636 HSPA8 P11142 Heat shock cognate 71 kDa protein chr11 GO:0019899 Not Cancer Driver No 149 0.231 251 52 0.207 0
HSPB1 HSPB1 P04792 Heat shock protein beta-1 chr7 GO:0019899 Not Cancer Driver No 10 0.049 118 8 0.068 20
HSPD1 HSPD1 P10809 60 kDa heat shock protein, mitochondrial chr2 GO:0019899 Not Cancer Driver No 61 0.106 82 6 0.073 2
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0019899 Not Cancer Driver No 52 0.11 8 1 0.125 0
IGBP1_ENST00000356413 IGBP1 P78318 Immunoglobulin-binding protein 1 chrX GO:0019899 Not Cancer Driver No 51 0.15 193 28 0.145 0
IGF2R IGF2R P11717 Cation-independent mannose-6-phosphate receptor chr6 GO:0019899 Not Cancer Driver No 318 0.128 255 20 0.078 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0019899 Not Cancer Driver No 55 0.118 165 23 0.139 1
IQCB1 IQCB1 Q15051 IQ calmodulin-binding motif-containing protein 1 chr3 GO:0019899 Not Cancer Driver No 72 0.12 88 8 0.091 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0019899 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0019899 Census Yes 153 0.146 92 9 0.098 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0019899 Not Cancer Driver No 124 0.157 66 5 0.076 30
JUN JUN P05412 Transcription factor Jun chr1 GO:0019899 Census Yes 35 0.106 281 25 0.089 0
JUND JUND P17535 Transcription factor JunD chr19 GO:0019899 Not Cancer Driver No 21 0.061 313 19 0.061 0
KANSL1L KANSL1L A0AUZ9 KAT8 regulatory NSL complex subunit 1-like protein chr2 GO:0019899 Not Cancer Driver No 127 0.129 410 51 0.124 0
KANSL1_ENST00000262419 KANSL1 Q7Z3B3 KAT8 regulatory NSL complex subunit 1 chr17 GO:0019899 Not Cancer Driver No 168 0.152 876 130 0.148 0
KAT8_ENST00000219797 KAT8 Q9H7Z6 Histone acetyltransferase KAT8 chr16 GO:0019899 Not Cancer Driver No 66 0.144 156 20 0.128 4
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0019899 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0019899 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4C KDM4C Q9H3R0 Lysine-specific demethylase 4C chr9 GO:0019899 Not Cancer Driver No 124 0.117 309 40 0.129 0
KIAA1614 KIAA1614 Q5VZ46 Uncharacterized protein KIAA1614 chr1 GO:0019899 Not Cancer Driver No 160 0.134 1160 159 0.137 0
KMT2E KMT2E Q8IZD2 Inactive histone-lysine N-methyltransferase 2E chr7 GO:0019899 Not Cancer Driver No 233 0.125 1613 198 0.123 4
KPNB1 KPNB1 Q14974 Importin subunit beta-1 chr17 GO:0019899 Not Cancer Driver No 92 0.105 94 11 0.117 0
KRT79 KRT79 Q5XKE5 Keratin, type II cytoskeletal 79 chr12 GO:0019899 Not Cancer Driver No 94 0.176 230 43 0.187 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0019899 Not Cancer Driver No 47 0.113 93 10 0.108 0
LAMP2_ENST00000200639 LAMP2 P13473 Lysosome-associated membrane glycoprotein 2 chrX GO:0019899 Not Cancer Driver No 43 0.105 55 7 0.127 1
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0019899 Census Yes 86 0.169 94 13 0.138 1
LCOR LCOR Q96JN0 Ligand-dependent corepressor chr10 GO:0019899 Not Cancer Driver No 54 0.125 388 46 0.119 0
LCORL LCORL Q8N3X6 Ligand-dependent nuclear receptor corepressor-like protein chr4 GO:0019899 Not Cancer Driver No 35 0.058 341 19 0.056 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0019899 Compendium Yes 56 0.136 177 29 0.164 0
LDB2 LDB2 O43679 LIM domain-binding protein 2 chr4 GO:0019899 Not Cancer Driver No 122 0.327 145 54 0.372 0
LDB3_ENST00000361373 LDB3 O75112 LIM domain-binding protein 3 chr10 GO:0019899 Not Cancer Driver No 107 0.147 529 71 0.134 4
LEO1 LEO1 Q8WVC0 RNA polymerase-associated protein LEO1 chr15 GO:0019899 Not Cancer Driver No 74 0.111 611 69 0.113 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0019899 Not Cancer Driver No 54 0.152 65 16 0.246 0
LMNB1 LMNB1 P20700 Lamin-B1 chr5 GO:0019899 Not Cancer Driver No 60 0.102 404 42 0.104 4
LONP1 LONP1 P36776 Lon protease homolog, mitochondrial chr19 GO:0019899 Not Cancer Driver No 99 0.103 175 15 0.086 10
LONP2 LONP2 Q86WA8 Lon protease homolog 2, peroxisomal chr16 GO:0019899 Not Cancer Driver No 116 0.136 163 26 0.16 0
LRPAP1 LRPAP1 P30533 Alpha-2-macroglobulin receptor-associated protein chr4 GO:0019899 Not Cancer Driver No 41 0.115 188 20 0.106 0
LUC7L2 LUC7L2 Q9Y383 Putative RNA-binding protein Luc7-like 2 chr7 GO:0019899 Not Cancer Driver No 59 0.151 262 45 0.172 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0019899 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAF1_ENST00000532522 MAF1 Q9H063 Repressor of RNA polymerase III transcription MAF1 homolog chr8 GO:0019899 Not Cancer Driver No 22 0.086 74 4 0.054 0
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0019899 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0019899 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0019899 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0019899 Census Yes 157 0.163 593 91 0.153 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0019899 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0019899 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0019899 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPK8IP3_ENST00000250894 MAPK8IP3 Q9UPT6 C-Jun-amino-terminal kinase-interacting protein 3 chr16 GO:0019899 Not Cancer Driver No 179 0.134 746 110 0.147 3
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0019899 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0019899 Not Cancer Driver No 43 0.107 92 5 0.054 0
MAPKAPK3 MAPKAPK3 Q16644 MAP kinase-activated protein kinase 3 chr3 GO:0019899 Not Cancer Driver No 35 0.092 117 12 0.103 1
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0019899 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0019899 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH6 MARCHF6 O60337 E3 ubiquitin-protein ligase MARCHF6 chr5 GO:0019899 Not Cancer Driver No 114 0.125 114 13 0.114 0
MARCH7 MARCHF7 Q9H992 E3 ubiquitin-protein ligase MARCHF7 chr2 GO:0019899 Not Cancer Driver No 85 0.121 550 68 0.124 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 GO:0019899 Not Cancer Driver No 14 0.042 328 14 0.043 0
MARVELD3_ENST00000268485 MARVELD3 Q96A59 MARVEL domain-containing protein 3 chr16 GO:0019899 Not Cancer Driver No 40 0.1 179 10 0.056 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0019899 Not Cancer Driver No 90 0.102 389 44 0.113 0
MAT2B MAT2B Q9NZL9 Methionine adenosyltransferase 2 subunit beta chr5 GO:0019899 Not Cancer Driver No 42 0.126 59 8 0.136 0
MCM10 MCM10 Q7L590 Protein MCM10 homolog chr10 GO:0019899 Not Cancer Driver No 152 0.174 535 102 0.191 1
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0019899 Not Cancer Driver No 104 0.115 275 38 0.138 1
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0019899 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0019899 Not Cancer Driver No 56 0.049 523 13 0.025 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0019899 Census, Compendium Yes 56 0.114 297 37 0.125 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 GO:0019899 Census, Compendium Yes 57 0.116 202 26 0.129 1
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0019899 Not Cancer Driver No 62 0.122 454 56 0.123 0
METTL21A_ENST00000406927 METTL21A Q8WXB1 Protein N-lysine methyltransferase METTL21A chr2 GO:0019899 Not Cancer Driver No 21 0.096 9 1 0.111 0
METTL6 METTL6 Q8TCB7 tRNA N(3)-methylcytidine methyltransferase METTL6 chr3 GO:0019899 Not Cancer Driver No 38 0.134 20 0 0.0 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0019899 Not Cancer Driver No 95 0.09 98 9 0.092 0
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX GO:0019899 Not Cancer Driver No 86 0.129 86 16 0.186 4
MID2 MID2 Q9UJV3 Probable E3 ubiquitin-protein ligase MID2 chrX GO:0019899 Not Cancer Driver No 112 0.152 95 24 0.253 1
MLEC MLEC Q14165 Malectin chr12 GO:0019899 Not Cancer Driver No 42 0.144 51 6 0.118 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0019899 Census Yes 92 0.122 208 22 0.106 85
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0019899 Not Cancer Driver No 73 0.071 11 0 0.0 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0019899 Census Yes 92 0.099 37 4 0.108 70
MSH3 MSH3 P20585 DNA mismatch repair protein Msh3 chr5 GO:0019899 Not Cancer Driver No 100 0.088 211 20 0.095 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0019899 Census Yes 154 0.113 386 41 0.106 6
MSN MSN P26038 Moesin chrX GO:0019899 Census, Compendium Yes 108 0.187 286 56 0.196 1
MST1R MST1R Q04912 Macrophage-stimulating protein receptor chr3 GO:0019899 Not Cancer Driver No 178 0.127 182 27 0.148 1
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0019899 Not Cancer Driver No 115 0.153 553 76 0.137 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0019899 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOZ2 MYOZ2 Q9NPC6 Myozenin-2 chr4 GO:0019899 Not Cancer Driver No 50 0.189 197 38 0.193 2
N4BP2L2_ENST00000267068 N4BP2L2 Q92802 NEDD4-binding protein 2-like 2 chr13 GO:0019899 Not Cancer Driver No 81 0.139 373 55 0.147 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0019899 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0019899 Not Cancer Driver No 39 0.028 67 4 0.06 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0019899 Not Cancer Driver No 109 0.106 142 18 0.127 0
NBR1 NBR1 Q14596 Next to BRCA1 gene 1 protein chr17 GO:0019899 Not Cancer Driver No 101 0.105 560 51 0.091 0
NCL NCL P19338 Nucleolin chr2 GO:0019899 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0019899 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:0019899 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0019899 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDUFAF7 NDUFAF7 Q7L592 Protein arginine methyltransferase NDUFAF7, mitochondrial chr2 GO:0019899 Not Cancer Driver No 53 0.12 19 3 0.158 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0019899 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0019899 Not Cancer Driver No 92 0.169 285 39 0.137 12
NELL1_ENST00000357134 NELL1 Q92832 Protein kinase C-binding protein NELL1 chr11 GO:0019899 Not Cancer Driver No 238 0.294 7 3 0.429 0
NELL2_ENST00000452445 NELL2 Q99435 Protein kinase C-binding protein NELL2 chr12 GO:0019899 Not Cancer Driver No 194 0.238 15 4 0.267 0
NFATC1 NFATC1 O95644 Nuclear factor of activated T-cells, cytoplasmic 1 chr18 GO:0019899 Not Cancer Driver No 173 0.183 713 130 0.182 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0019899 Compendium Yes 37 0.117 102 9 0.088 1
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0019899 Not Cancer Driver No 35 0.117 83 8 0.096 2
NKAIN1 NKAIN1 Q4KMZ8 Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 chr1 GO:0019899 Not Cancer Driver No 20 0.097 0 0 0.0 0
NKD2 NKD2 Q969F2 Protein naked cuticle homolog 2 chr5 GO:0019899 Not Cancer Driver No 64 0.142 451 64 0.142 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0019899 Census, Compendium Yes 41 0.111 334 39 0.117 7
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0019899 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0019899 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP7_ENST00000590030 NLRP7 Q8WX94 NACHT, LRR and PYD domains-containing protein 7 chr19 GO:0019899 Not Cancer Driver No 300 0.306 71 20 0.282 9
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0019899 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0019899 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOP14 NOP14 P78316 Nucleolar protein 14 chr4 GO:0019899 Not Cancer Driver No 87 0.102 521 46 0.088 0
NOP56 NOP56 O00567 Nucleolar protein 56 chr20 GO:0019899 Not Cancer Driver No 83 0.14 191 34 0.178 0
NOP58 NOP58 Q9Y2X3 Nucleolar protein 58 chr2 GO:0019899 Not Cancer Driver No 47 0.089 156 14 0.09 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0019899 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0019899 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0019899 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH3 NOTCH3 Q9UM47 Neurogenic locus notch homolog protein 3 chr19 GO:0019899 Not Cancer Driver No 306 0.132 557 81 0.145 110
NOXA1 NOXA1 Q86UR1 NADPH oxidase activator 1 chr9 GO:0019899 Not Cancer Driver No 27 0.057 215 14 0.065 0
NOXO1 NOXO1 Q8NFA2 NADPH oxidase organizer 1 chr16 GO:0019899 Not Cancer Driver No 29 0.077 182 9 0.049 0
NPC2 NPC2 P61916 NPC intracellular cholesterol transporter 2 chr14 GO:0019899 Not Cancer Driver No 8 0.053 0 0 0.0 7
NPLOC4 NPLOC4 Q8TAT6 Nuclear protein localization protein 4 homolog chr17 GO:0019899 Not Cancer Driver No 78 0.128 47 8 0.17 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0019899 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0019899 Not Cancer Driver No 60 0.13 133 29 0.218 24
NUFIP1 NUFIP1 Q9UHK0 Nuclear fragile X mental retardation-interacting protein 1 chr13 GO:0019899 Not Cancer Driver No 72 0.145 403 49 0.122 0
P4HB P4HB P07237 Protein disulfide-isomerase chr17 GO:0019899 Not Cancer Driver No 61 0.12 79 15 0.19 1
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0019899 Not Cancer Driver No 42 0.102 82 11 0.134 7
PARD6A PARD6A Q9NPB6 Partitioning defective 6 homolog alpha chr16 GO:0019899 Not Cancer Driver No 25 0.072 177 13 0.073 0
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 GO:0019899 Not Cancer Driver No 50 0.134 166 23 0.139 0
PARD6G PARD6G Q9BYG4 Partitioning defective 6 homolog gamma chr18 GO:0019899 Not Cancer Driver No 32 0.085 175 11 0.063 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0019899 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0019899 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0019899 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:0019899 Compendium Yes 218 0.126 325 40 0.123 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0019899 Not Cancer Driver No 110 0.129 45 3 0.067 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0019899 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0019899 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAXX PAXX Q9BUH6 Protein PAXX chr9 GO:0019899 Not Cancer Driver No 22 0.108 121 17 0.14 0
PCBP2_ENST00000439930 PCBP2 Q15366 Poly(rC)-binding protein 2 chr12 GO:0019899 Not Cancer Driver No 40 0.11 200 24 0.12 0
PCCA PCCA P05165 Propionyl-CoA carboxylase alpha chain, mitochondrial chr13 GO:0019899 Not Cancer Driver No 102 0.14 42 14 0.333 16
PCIF1 PCIF1 Q9H4Z3 mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase chr20 GO:0019899 Not Cancer Driver No 77 0.109 288 37 0.128 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0019899 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDCD2 PDCD2 Q16342 Programmed cell death protein 2 chr6 GO:0019899 Not Cancer Driver No 32 0.093 42 6 0.143 0
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0019899 Not Cancer Driver No 135 0.121 393 37 0.094 0
PDE4D PDE4D Q08499 cAMP-specific 3',5'-cyclic phosphodiesterase 4D chr5 GO:0019899 Not Cancer Driver No 86 0.106 464 54 0.116 12
PDE4DIP_ENST00000369354 PDE4DIP Q5VU43 Myomegalin chr1 GO:0019899 Census, Compendium Yes 555 0.237 1633 395 0.242 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0019899 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0019899 Not Cancer Driver No 89 0.149 372 57 0.153 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0019899 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDZD3_ENST00000531114 PDZD3 Q86UT5 Na(+)/H(+) exchange regulatory cofactor NHE-RF4 chr11 GO:0019899 Not Cancer Driver No 58 0.102 199 19 0.095 0
PEBP1 PEBP1 P30086 Phosphatidylethanolamine-binding protein 1 chr12 GO:0019899 Not Cancer Driver No 23 0.123 76 13 0.171 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:0019899 Not Cancer Driver No 134 0.119 610 82 0.134 0
PEX19 PEX19 P40855 Peroxisomal biogenesis factor 19 chr1 GO:0019899 Not Cancer Driver No 41 0.137 266 38 0.143 0
PEX26 PEX26 Q7Z412 Peroxisome assembly protein 26 chr22 GO:0019899 Not Cancer Driver No 25 0.082 40 2 0.05 4
PEX5_ENST00000420616 PEX5 P50542 Peroxisomal targeting signal 1 receptor chr12 GO:0019899 Not Cancer Driver No 73 0.114 321 36 0.112 2
PEX7 PEX7 O00628 Peroxisomal targeting signal 2 receptor chr6 GO:0019899 Not Cancer Driver No 32 0.099 0 0 0.0 2
PGR PGR P06401 Progesterone receptor chr11 GO:0019899 Not Cancer Driver No 161 0.173 480 55 0.115 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0019899 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 GO:0019899 Not Cancer Driver No 62 0.109 277 29 0.105 0
PHF6_ENST00000370803 PHF6 Q8IWS0 PHD finger protein 6 chrX GO:0019899 Census, Compendium Yes 52 0.142 172 19 0.11 6
PHKG1_ENST00000297373 PHKG1 Q16816 Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform chr7 GO:0019899 Not Cancer Driver No 58 0.15 23 4 0.174 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:0019899 Not Cancer Driver No 48 0.118 50 6 0.12 4
PHLDB3 PHLDB3 Q6NSJ2 Pleckstrin homology-like domain family B member 3 chr19 GO:0019899 Not Cancer Driver No 74 0.116 462 50 0.108 0
PIAS1_ENST00000249636 PIAS1 O75925 E3 SUMO-protein ligase PIAS1 chr15 GO:0019899 Not Cancer Driver No 80 0.123 241 43 0.178 0
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0019899 Not Cancer Driver No 70 0.111 266 31 0.117 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0019899 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0019899 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0019899 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0019899 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIN1 PIN1 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 chr19 GO:0019899 Not Cancer Driver No 17 0.104 115 12 0.104 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0019899 Not Cancer Driver No 57 0.098 99 13 0.131 23
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0019899 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0019899 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIA PKIA P61925 cAMP-dependent protein kinase inhibitor alpha chr8 GO:0019899 Not Cancer Driver No 18 0.237 76 18 0.237 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0019899 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKP2 PKP2 Q99959 Plakophilin-2 chr12 GO:0019899 Not Cancer Driver No 176 0.2 434 98 0.226 8
PKP3 PKP3 Q9Y446 Plakophilin-3 chr11 GO:0019899 Not Cancer Driver No 72 0.09 357 22 0.062 0
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0019899 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0019899 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0019899 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCE1 PLCE1 Q9P212 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 chr10 GO:0019899 Not Cancer Driver No 367 0.159 780 107 0.137 1
PLEK PLEK P08567 Pleckstrin chr2 GO:0019899 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLG PLG P00747 Plasminogen chr6 GO:0019899 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0019899 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0019899 Not Cancer Driver No 49 0.106 192 21 0.109 0
PLN PLN P26678 Cardiac phospholamban chr6 GO:0019899 Not Cancer Driver No 10 0.192 0 0 0.0 3
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0019899 Not Cancer Driver No 43 0.135 92 13 0.141 0
PLSCR4_ENST00000446574 PLSCR4 Q9NRQ2 Phospholipid scramblase 4 chr3 GO:0019899 Not Cancer Driver No 68 0.207 108 11 0.102 0
PMS1 PMS1 P54277 PMS1 protein homolog 1 chr2 GO:0019899 Census Yes 114 0.122 283 38 0.134 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0019899 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0019899 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0019899 Not Cancer Driver No 64 0.132 46 4 0.087 3
POMZP3 POMZP3 Q6PJE2 POM121 and ZP3 fusion protein chr7 GO:0019899 Not Cancer Driver No 27 0.144 87 13 0.149 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0019899 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0019899 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0019899 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0019899 Census Yes 72 0.143 44 4 0.091 3
PPEF2 PPEF2 O14830 Serine/threonine-protein phosphatase with EF-hands 2 chr4 GO:0019899 Not Cancer Driver No 144 0.191 130 29 0.223 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0019899 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPME1_ENST00000328257 PPME1 Q9Y570 Protein phosphatase methylesterase 1 chr11 GO:0019899 Not Cancer Driver No 35 0.091 146 9 0.062 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0019899 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0019899 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRDM12 PRDM12 Q9H4Q4 PR domain zinc finger protein 12 chr9 GO:0019899 Not Cancer Driver No 26 0.071 82 1 0.012 6
PRDM4 PRDM4 Q9UKN5 PR domain zinc finger protein 4 chr12 GO:0019899 Not Cancer Driver No 92 0.115 362 40 0.11 0
PREX1 PREX1 Q8TCU6 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein chr20 GO:0019899 Not Cancer Driver No 297 0.179 307 55 0.179 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0019899 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0019899 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2A PRKAR2A P13861 cAMP-dependent protein kinase type II-alpha regulatory subunit chr3 GO:0019899 Not Cancer Driver No 37 0.092 149 13 0.087 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0019899 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0019899 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0019899 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0019899 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0019899 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0019899 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCSH_ENST00000589838 PRKCSH P14314 Glucosidase 2 subunit beta chr19 GO:0019899 Not Cancer Driver No 68 0.129 320 41 0.128 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0019899 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0019899 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0019899 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0019899 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0019899 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0019899 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT8 PRMT8 Q9NR22 Protein arginine N-methyltransferase 8 chr12 GO:0019899 Not Cancer Driver No 94 0.239 61 16 0.262 0
PRTN3 PRTN3 P24158 Myeloblastin chr19 GO:0019899 Not Cancer Driver No 20 0.078 46 1 0.022 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0019899 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSENEN_ENST00000222266 PSENEN Q9NZ42 Gamma-secretase subunit PEN-2 chr19 GO:0019899 Not Cancer Driver No 17 0.168 0 0 0.0 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0019899 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0019899 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0019899 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0019899 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0019899 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0019899 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPA_ENST00000337738 PTPA Q15257 Serine/threonine-protein phosphatase 2A activator chr9 GO:0019899 Not Cancer Driver No 40 0.112 63 2 0.032 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0019899 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN3 PTPN3 P26045 Tyrosine-protein phosphatase non-receptor type 3 chr9 GO:0019899 Not Cancer Driver No 139 0.152 214 28 0.131 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0019899 Not Cancer Driver No 184 0.138 401 61 0.152 0
PUS7_ENST00000469408 PUS7 Q96PZ0 Pseudouridylate synthase 7 homolog chr7 GO:0019899 Not Cancer Driver No 73 0.11 162 17 0.105 1
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0019899 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0019899 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0019899 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0019899 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD23A RAD23A P54725 UV excision repair protein RAD23 homolog A chr19 GO:0019899 Not Cancer Driver No 50 0.138 283 41 0.145 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0019899 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0019899 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0019899 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALA RALA P11233 Ras-related protein Ral-A chr7 GO:0019899 Not Cancer Driver No 34 0.165 34 3 0.088 5
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0019899 Not Cancer Driver No 36 0.175 35 5 0.143 0
RANBP9 RANBP9 Q96S59 Ran-binding protein 9 chr6 GO:0019899 Not Cancer Driver No 73 0.1 413 30 0.073 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0019899 Census, Compendium Yes 70 0.152 167 14 0.084 0
RCOR1 RCOR1 Q9UKL0 REST corepressor 1 chr14 GO:0019899 Not Cancer Driver No 47 0.097 324 28 0.086 0
RCOR2 RCOR2 Q8IZ40 REST corepressor 2 chr11 GO:0019899 Not Cancer Driver No 57 0.109 369 35 0.095 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0019899 Not Cancer Driver No 71 0.122 297 37 0.125 1
RELA RELA Q04206 Transcription factor p65 chr11 GO:0019899 Compendium Yes 75 0.136 400 48 0.12 0
RESF1 RESF1 Q9HCM1 Retroelement silencing factor 1 chr12 GO:0019899 Not Cancer Driver No 217 0.124 1528 185 0.121 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0019899 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0019899 Not Cancer Driver No 38 0.112 20 1 0.05 0
RHBDD2 RHBDD2 Q6NTF9 Rhomboid domain-containing protein 2 chr7 GO:0019899 Not Cancer Driver No 48 0.132 120 23 0.192 0
RIOK3 RIOK3 O14730 Serine/threonine-protein kinase RIO3 chr18 GO:0019899 Not Cancer Driver No 58 0.112 225 21 0.093 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0019899 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF125 RNF125 Q96EQ8 E3 ubiquitin-protein ligase RNF125 chr18 GO:0019899 Not Cancer Driver No 35 0.151 26 1 0.038 3
RNF13_ENST00000392894 RNF13 O43567 E3 ubiquitin-protein ligase RNF13 chr3 GO:0019899 Not Cancer Driver No 45 0.118 107 17 0.159 2
RNF14 RNF14 Q9UBS8 E3 ubiquitin-protein ligase RNF14 chr5 GO:0019899 Not Cancer Driver No 52 0.11 40 8 0.2 0
RNF144A RNF144A P50876 E3 ubiquitin-protein ligase RNF144A chr2 GO:0019899 Not Cancer Driver No 63 0.216 0 0 0.0 0
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0019899 Not Cancer Driver No 32 0.106 4 1 0.25 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 GO:0019899 Not Cancer Driver No 80 0.135 190 26 0.137 0
RNF19A RNF19A Q9NV58 E3 ubiquitin-protein ligase RNF19A chr8 GO:0019899 Not Cancer Driver No 112 0.134 387 55 0.142 0
RNF19B RNF19B Q6ZMZ0 E3 ubiquitin-protein ligase RNF19B chr1 GO:0019899 Not Cancer Driver No 58 0.079 344 24 0.07 0
RNF217 RNF217 Q8TC41 E3 ubiquitin-protein ligase RNF217 chr6 GO:0019899 Not Cancer Driver No 70 0.129 203 13 0.064 0
RNF40 RNF40 O75150 E3 ubiquitin-protein ligase BRE1B chr16 GO:0019899 Not Cancer Driver No 132 0.132 645 80 0.124 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0019899 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0019899 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPS19BP1 RPS19BP1 Q86WX3 Active regulator of SIRT1 chr22 GO:0019899 Not Cancer Driver No 5 0.037 112 5 0.045 0
RPS2 RPS2 P15880 40S ribosomal protein S2 chr16 GO:0019899 Not Cancer Driver No 34 0.116 85 14 0.165 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0019899 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0019899 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRN3 RRN3 Q9NYV6 RNA polymerase I-specific transcription initiation factor RRN3 chr16 GO:0019899 Not Cancer Driver No 66 0.101 115 15 0.13 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0019899 Not Cancer Driver No 144 0.118 474 64 0.135 14
RTF1 RTF1 Q92541 RNA polymerase-associated protein RTF1 homolog chr15 GO:0019899 Not Cancer Driver No 83 0.117 568 67 0.118 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0019899 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0019899 Not Cancer Driver No 62 0.134 100 13 0.13 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0019899 Compendium Yes 90 0.195 184 26 0.141 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0019899 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S100A1 S100A1 P23297 Protein S100-A1 chr1 GO:0019899 Not Cancer Driver No 13 0.138 9 0 0.0 0
SAE1 SAE1 Q9UBE0 SUMO-activating enzyme subunit 1 chr19 GO:0019899 Not Cancer Driver No 39 0.113 90 6 0.067 0
SARS_ENST00000234677 SARS1 P49591 Serine--tRNA ligase, cytoplasmic chr1 GO:0019899 Not Cancer Driver No 56 0.109 83 4 0.048 1
SART3 SART3 Q15020 Squamous cell carcinoma antigen recognized by T-cells 3 chr12 GO:0019899 Not Cancer Driver No 101 0.105 404 45 0.111 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0019899 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCAF1 SCAF1 Q9H7N4 Splicing factor, arginine/serine-rich 19 chr19 GO:0019899 Not Cancer Driver No 135 0.103 1307 134 0.103 0
SCAF4 SCAF4 O95104 SR-related and CTD-associated factor 4 chr21 GO:0019899 Not Cancer Driver No 162 0.141 938 132 0.141 0
SCAF8_ENST00000367178 SCAF8 Q9UPN6 SR-related and CTD-associated factor 8 chr6 GO:0019899 Not Cancer Driver No 155 0.122 939 118 0.126 0
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 GO:0019899 Not Cancer Driver No 61 0.128 13 3 0.231 1
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0019899 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCNM1 SCNM1 Q9BWG6 Sodium channel modifier 1 chr1 GO:0019899 Not Cancer Driver No 31 0.135 172 23 0.134 0
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0019899 Census, Compendium Yes 34 0.172 110 25 0.227 0
SDF2L1 SDF2L1 Q9HCN8 Stromal cell-derived factor 2-like protein 1 chr22 GO:0019899 Not Cancer Driver No 16 0.072 130 9 0.069 0
SELE SELE P16581 E-selectin chr1 GO:0019899 Not Cancer Driver No 137 0.225 12 0 0.0 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0019899 Not Cancer Driver No 7 0.037 122 6 0.049 0
SERPINA5_ENST00000554276 SERPINA5 P05154 Plasma serine protease inhibitor chr14 GO:0019899 Not Cancer Driver No 103 0.254 24 17 0.708 0
SERPINB12_ENST00000269491 SERPINB12 Q96P63 Serpin B12 chr18 GO:0019899 Not Cancer Driver No 82 0.202 21 6 0.286 0
SERPINB4 SERPINB4 P48594 Serpin B4 chr18 GO:0019899 Not Cancer Driver No 120 0.308 48 18 0.375 0
SETMAR SETMAR Q53H47 Histone-lysine N-methyltransferase SETMAR chr3 GO:0019899 Not Cancer Driver No 62 0.091 154 12 0.078 0
SH2B1 SH2B1 Q9NRF2 SH2B adapter protein 1 chr16 GO:0019899 Not Cancer Driver No 98 0.13 612 84 0.137 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0019899 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHC1_ENST00000368445 SHC1 P29353 SHC-transforming protein 1 chr1 GO:0019899 Not Cancer Driver No 84 0.144 397 58 0.146 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0019899 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0019899 Not Cancer Driver No 48 0.148 68 3 0.044 0
SIAH3 SIAH3 Q8IW03 Seven in absentia homolog 3 chr13 GO:0019899 Not Cancer Driver No 60 0.223 51 9 0.176 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0019899 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0019899 Not Cancer Driver No 56 0.144 85 17 0.2 0
SLC26A9_ENST00000367135 SLC26A9 Q7LBE3 Solute carrier family 26 member 9 chr1 GO:0019899 Not Cancer Driver No 163 0.206 86 18 0.209 0
SLC27A2 SLC27A2 O14975 Very long-chain acyl-CoA synthetase chr15 GO:0019899 Not Cancer Driver No 95 0.153 4 0 0.0 0
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0019899 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC4A2 SLC4A2 P04920 Anion exchange protein 2 chr7 GO:0019899 Not Cancer Driver No 150 0.121 509 62 0.122 0
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0019899 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0019899 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0019899 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLN_ENST00000525934 SLN O00631 Sarcolipin chr11 GO:0019899 Not Cancer Driver No 8 0.258 0 0 0.0 0
SLPI SLPI P03973 Antileukoproteinase chr20 GO:0019899 Not Cancer Driver No 20 0.152 0 0 0.0 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0019899 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0019899 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0019899 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0019899 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0019899 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMG5 SMG5 Q9UPR3 Nonsense-mediated mRNA decay factor SMG5 chr1 GO:0019899 Not Cancer Driver No 132 0.13 295 51 0.173 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0019899 Not Cancer Driver No 166 0.117 751 97 0.129 0
SMG7_ENST00000347615 SMG7 Q92540 Nonsense-mediated mRNA decay factor SMG7 chr1 GO:0019899 Not Cancer Driver No 134 0.118 664 82 0.123 0
SNRPD3 SNRPD3 P62318 Small nuclear ribonucleoprotein Sm D3 chr22 GO:0019899 Not Cancer Driver No 20 0.159 43 13 0.302 0
SNTA1 SNTA1 Q13424 Alpha-1-syntrophin chr20 GO:0019899 Not Cancer Driver No 43 0.085 238 14 0.059 2
SNU13_ENST00000355257 SNU13 P55769 NHP2-like protein 1 chr22 GO:0019899 Not Cancer Driver No 17 0.133 2 0 0.0 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0019899 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX10_ENST00000396376 SNX10 Q9Y5X0 Sorting nexin-10 chr7 GO:0019899 Not Cancer Driver No 24 0.119 52 8 0.154 4
SNX12 SNX12 Q9UMY4 Sorting nexin-12 chrX GO:0019899 Not Cancer Driver No 22 0.136 28 4 0.143 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0019899 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0019899 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORT1 SORT1 Q99523 Sortilin chr1 GO:0019899 Not Cancer Driver No 69 0.083 110 2 0.018 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0019899 Compendium Yes 86 0.169 495 82 0.166 18
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0019899 Not Cancer Driver No 96 0.122 599 71 0.119 0
SP7 SP7 Q8TDD2 Transcription factor Sp7 chr12 GO:0019899 Not Cancer Driver No 63 0.146 332 44 0.133 0
SPAG9 SPAG9 O60271 C-Jun-amino-terminal kinase-interacting protein 4 chr17 GO:0019899 Not Cancer Driver No 128 0.097 841 81 0.096 0
SPATA2_ENST00000289431 SPATA2 Q9UM82 Spermatogenesis-associated protein 2 chr20 GO:0019899 Not Cancer Driver No 70 0.135 235 39 0.166 0
SPDL1 SPDL1 Q96EA4 Protein Spindly chr5 GO:0019899 Not Cancer Driver No 75 0.124 342 43 0.126 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0019899 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPTY2D1 SPTY2D1 Q68D10 Protein SPT2 homolog chr11 GO:0019899 Not Cancer Driver No 94 0.137 670 89 0.133 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0019899 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0019899 Census Yes 53 0.099 130 11 0.085 1
SRSF1 SRSF1 Q07955 Serine/arginine-rich splicing factor 1 chr17 GO:0019899 Not Cancer Driver No 41 0.165 198 34 0.172 0
SRSF2 SRSF2 Q01130 Serine/arginine-rich splicing factor 2 chr17 GO:0019899 Census, Compendium Yes 38 0.172 219 38 0.174 0
SRSF3_ENST00000620941 SRSF3 P84103 Serine/arginine-rich splicing factor 3 chr6 GO:0019899 Census Yes 31 0.189 125 27 0.216 0
SRSF5_ENST00000557154 SRSF5 Q13243 Serine/arginine-rich splicing factor 5 chr14 GO:0019899 Not Cancer Driver No 50 0.184 189 40 0.212 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0019899 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0019899 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0019899 Not Cancer Driver No 68 0.119 486 54 0.111 0
STBD1 STBD1 O95210 Starch-binding domain-containing protein 1 chr4 GO:0019899 Not Cancer Driver No 47 0.131 229 31 0.135 0
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0019899 Not Cancer Driver No 71 0.235 112 29 0.259 0
STK38 STK38 Q15208 Serine/threonine-protein kinase 38 chr6 GO:0019899 Not Cancer Driver No 57 0.123 77 6 0.078 0
STRN STRN O43815 Striatin chr2 GO:0019899 Census, Compendium Yes 97 0.124 348 43 0.124 0
STRN3 STRN3 Q13033 Striatin-3 chr14 GO:0019899 Not Cancer Driver No 93 0.117 366 42 0.115 0
STRN4_ENST00000263280 STRN4 Q9NRL3 Striatin-4 chr19 GO:0019899 Not Cancer Driver No 84 0.112 407 40 0.098 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0019899 Not Cancer Driver No 35 0.116 112 14 0.125 12
STXBP1_ENST00000373299 STXBP1 P61764 Syntaxin-binding protein 1 chr9 GO:0019899 Not Cancer Driver No 97 0.163 111 23 0.207 18
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 GO:0019899 Not Cancer Driver No 35 0.107 249 28 0.112 0
SUMO1_ENST00000392245 SUMO1 P63165 Small ubiquitin-related modifier 1 chr2 GO:0019899 Not Cancer Driver No 10 0.099 76 7 0.092 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:0019899 Not Cancer Driver No 165 0.152 572 87 0.152 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0019899 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0019899 Census Yes 96 0.151 131 27 0.206 5
SYNE1 SYNE1 Q8NF91 Nesprin-1 chr6 GO:0019899 Not Cancer Driver No 1694 0.193 2530 530 0.209 2
SYVN1 SYVN1 Q86TM6 E3 ubiquitin-protein ligase synoviolin chr11 GO:0019899 Not Cancer Driver No 63 0.102 284 32 0.113 0
TAB1 TAB1 Q15750 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chr22 GO:0019899 Not Cancer Driver No 81 0.161 232 34 0.147 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0019899 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF7 TAF7 Q15545 Transcription initiation factor TFIID subunit 7 chr5 GO:0019899 Not Cancer Driver No 40 0.115 258 31 0.12 0
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0019899 Not Cancer Driver No 25 0.095 203 19 0.094 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0019899 Census Yes 54 0.163 305 53 0.174 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0019899 Not Cancer Driver No 191 0.155 666 102 0.153 0
TARBP2 TARBP2 Q15633 RISC-loading complex subunit TARBP2 chr12 GO:0019899 Not Cancer Driver No 45 0.123 203 22 0.108 0
TBP TBP P20226 TATA-box-binding protein chr6 GO:0019899 Not Cancer Driver No 40 0.118 164 14 0.085 0
TCF3 TCF3 P15923 Transcription factor E2-alpha chr19 GO:0019899 Census Yes 52 0.08 649 52 0.08 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0019899 Compendium Yes 68 0.082 102 6 0.059 5
TDG TDG Q13569 G/T mismatch-specific thymine DNA glycosylase chr12 GO:0019899 Not Cancer Driver No 75 0.183 185 31 0.168 0
TEP1 TEP1 Q99973 Telomerase protein component 1 chr14 GO:0019899 Not Cancer Driver No 332 0.126 396 67 0.169 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0019899 Not Cancer Driver No 33 0.061 361 20 0.055 0
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0019899 Not Cancer Driver No 127 0.244 284 84 0.296 0
TFEB_ENST00000403298 TFEB P19484 Transcription factor EB chr6 GO:0019899 Census Yes 58 0.122 429 47 0.11 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0019899 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0019899 Census, Compendium Yes 106 0.187 60 16 0.267 25
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0019899 Not Cancer Driver No 61 0.116 149 21 0.141 38
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0019899 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0019899 Not Cancer Driver No 28 0.127 80 6 0.075 0
TMBIM6_ENST00000549385 TMBIM6 P55061 Bax inhibitor 1 chr12 GO:0019899 Not Cancer Driver No 16 0.068 3 0 0.0 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 GO:0019899 Not Cancer Driver No 31 0.113 56 4 0.071 1
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0019899 Census Yes 7 0.159 44 7 0.159 0
TMTC4_ENST00000376234 TMTC4 Q5T4D3 Protein O-mannosyl-transferase TMTC4 chr13 GO:0019899 Not Cancer Driver No 105 0.142 0 0 0.0 0
TNIP1_ENST00000522226 TNIP1 Q15025 TNFAIP3-interacting protein 1 chr5 GO:0019899 Not Cancer Driver No 85 0.134 625 83 0.133 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0019899 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0019899 Not Cancer Driver No 117 0.1 255 24 0.094 0
TOLLIP TOLLIP Q9H0E2 Toll-interacting protein chr11 GO:0019899 Not Cancer Driver No 38 0.139 81 12 0.148 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0019899 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0019899 Not Cancer Driver No 154 0.095 543 46 0.085 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0019899 Not Cancer Driver No 149 0.143 795 105 0.132 0
TOR1AIP1_ENST00000606911 TOR1AIP1 Q5JTV8 Torsin-1A-interacting protein 1 chr1 GO:0019899 Not Cancer Driver No 71 0.122 401 44 0.11 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0019899 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0019899 Census Yes 311 0.132 1990 266 0.134 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0019899 Not Cancer Driver No 26 0.083 74 5 0.068 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 GO:0019899 Not Cancer Driver No 51 0.123 63 9 0.143 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0019899 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0019899 Compendium Yes 61 0.107 101 9 0.089 1
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0019899 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 GO:0019899 Not Cancer Driver No 61 0.11 59 5 0.085 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0019899 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0019899 Not Cancer Driver No 86 0.462 129 67 0.519 0
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0019899 Not Cancer Driver No 47 0.126 91 5 0.055 0
TRIB2 TRIB2 Q92519 Tribbles homolog 2 chr2 GO:0019899 Not Cancer Driver No 64 0.187 43 5 0.116 0
TRIB3_ENST00000217233 TRIB3 Q96RU7 Tribbles homolog 3 chr20 GO:0019899 Not Cancer Driver No 65 0.182 114 24 0.211 0
TRIM68 TRIM68 Q6AZZ1 E3 ubiquitin-protein ligase TRIM68 chr11 GO:0019899 Not Cancer Driver No 74 0.153 37 7 0.189 0
TRIM72 TRIM72 Q6ZMU5 Tripartite motif-containing protein 72 chr16 GO:0019899 Not Cancer Driver No 54 0.113 69 14 0.203 0
TRIP4 TRIP4 Q15650 Activating signal cointegrator 1 chr15 GO:0019899 Not Cancer Driver No 71 0.122 176 27 0.153 0
TRPC1 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0019899 Not Cancer Driver No 143 0.18 52 11 0.212 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0019899 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0019899 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSPAN10_ENST00000611590 TSPAN10 Q9H1Z9 Tetraspanin-10 chr17 GO:0019899 Not Cancer Driver No 29 0.082 81 6 0.074 0
TSPAN14_ENST00000372156 TSPAN14 Q8NG11 Tetraspanin-14 chr10 GO:0019899 Not Cancer Driver No 38 0.141 0 0 0.0 0
TSPAN15 TSPAN15 O95858 Tetraspanin-15 chr10 GO:0019899 Not Cancer Driver No 29 0.099 0 0 0.0 0
TSPAN17_ENST00000515708 TSPAN17 Q96FV3 Tetraspanin-17 chr5 GO:0019899 Not Cancer Driver No 23 0.085 0 0 0.0 0
TSPAN33 TSPAN33 Q86UF1 Tetraspanin-33 chr7 GO:0019899 Not Cancer Driver No 26 0.092 0 0 0.0 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 GO:0019899 Not Cancer Driver No 49 0.183 0 0 0.0 0
TSPYL1 TSPYL1 Q9H0U9 Testis-specific Y-encoded-like protein 1 chr6 GO:0019899 Not Cancer Driver No 48 0.11 239 31 0.13 0
TTN_ENST00000615779 TTN Q8WZ42 Titin chr2 GO:0019899 Not Cancer Driver No 7917 0.23 12926 2861 0.221 10
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 GO:0019899 Not Cancer Driver No 66 0.149 218 29 0.133 0
TUT1_ENST00000476907 TUT1 Q9H6E5 Speckle targeted PIP5K1A-regulated poly(A) polymerase chr11 GO:0019899 Not Cancer Driver No 97 0.111 410 50 0.122 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0019899 Not Cancer Driver No 34 0.097 59 8 0.136 0
U2AF2 U2AF2 P26368 Splicing factor U2AF 65 kDa subunit chr19 GO:0019899 Compendium Yes 78 0.164 191 28 0.147 0
UBA2 UBA2 Q9UBT2 SUMO-activating enzyme subunit 2 chr19 GO:0019899 Not Cancer Driver No 84 0.131 219 33 0.151 0
UBE2I UBE2I P63279 SUMO-conjugating enzyme UBC9 chr16 GO:0019899 Not Cancer Driver No 16 0.101 16 3 0.188 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0019899 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3D UBE3D Q7Z6J8 E3 ubiquitin-protein ligase E3D chr6 GO:0019899 Not Cancer Driver No 51 0.131 9 3 0.333 0
UBE4B UBE4B O95155 Ubiquitin conjugation factor E4 B chr1 GO:0019899 Not Cancer Driver No 158 0.121 434 49 0.113 0
UBXN1_ENST00000301935 UBXN1 Q04323 UBX domain-containing protein 1 chr11 GO:0019899 Not Cancer Driver No 35 0.118 271 33 0.122 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0019899 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT1A10 UGT1A10 Q9HAW8 UDP-glucuronosyltransferase 1A10 chr2 GO:0019899 Not Cancer Driver No 114 0.215 11 2 0.182 0
UGT1A3 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0019899 Not Cancer Driver No 98 0.184 11 2 0.182 0
UGT1A4 UGT1A4 P22310 UDP-glucuronosyltransferase 1A4 chr2 GO:0019899 Not Cancer Driver No 99 0.185 11 2 0.182 0
UGT1A6 UGT1A6 P19224 UDP-glucuronosyltransferase 1-6 chr2 GO:0019899 Not Cancer Driver No 96 0.18 11 2 0.182 0
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 GO:0019899 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A8 UGT1A8 Q9HAW9 UDP-glucuronosyltransferase 1A8 chr2 GO:0019899 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A9 UGT1A9 O60656 UDP-glucuronosyltransferase 1A9 chr2 GO:0019899 Not Cancer Driver No 121 0.228 11 2 0.182 0
UHMK1 UHMK1 Q8TAS1 Serine/threonine-protein kinase Kist chr1 GO:0019899 Not Cancer Driver No 42 0.1 14 2 0.143 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0019899 Not Cancer Driver No 52 0.168 271 44 0.162 0
USP22 USP22 Q9UPT9 Ubiquitin carboxyl-terminal hydrolase 22 chr17 GO:0019899 Not Cancer Driver No 64 0.122 50 1 0.02 0
USP25_ENST00000285679 USP25 Q9UHP3 Ubiquitin carboxyl-terminal hydrolase 25 chr21 GO:0019899 Not Cancer Driver No 135 0.128 354 55 0.155 0
VAPB VAPB O95292 Vesicle-associated membrane protein-associated protein B/C chr20 GO:0019899 Not Cancer Driver No 16 0.066 138 8 0.058 3
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0019899 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPKMT VCPKMT Q9H867 Protein N-lysine methyltransferase METTL21D chr14 GO:0019899 Not Cancer Driver No 24 0.105 5 0 0.0 0
VHL VHL P40337 von Hippel-Lindau disease tumor suppressor chr3 GO:0019899 Census, Compendium Yes 142 0.667 117 36 0.308 133
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0019899 Not Cancer Driver No 52 0.167 135 19 0.141 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0019899 Census, Compendium Yes 75 0.149 400 55 0.138 30
WDR70 WDR70 Q9NW82 WD repeat-containing protein 70 chr5 GO:0019899 Not Cancer Driver No 97 0.148 363 57 0.157 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 GO:0019899 Not Cancer Driver No 60 0.096 288 33 0.115 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0019899 Not Cancer Driver No 105 0.118 203 10 0.049 39
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0019899 Not Cancer Driver No 79 0.191 108 9 0.083 3
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0019899 Not Cancer Driver No 89 0.179 55 6 0.109 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0019899 Not Cancer Driver No 85 0.134 426 53 0.124 1
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0019899 Not Cancer Driver No 65 0.12 62 10 0.161 0
YWHAB_ENST00000353703 YWHAB P31946 14-3-3 protein beta/alpha chr20 GO:0019899 Not Cancer Driver No 22 0.089 109 4 0.037 0
YWHAE YWHAE P62258 14-3-3 protein epsilon chr17 GO:0019899 Census Yes 32 0.125 41 3 0.073 0
YWHAG YWHAG P61981 14-3-3 protein gamma chr7 GO:0019899 Not Cancer Driver No 26 0.105 77 9 0.117 2
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0019899 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0019899 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZFHX3_ENST00000268489 ZFHX3 Q15911 Zinc finger homeobox protein 3 chr16 GO:0019899 Census, Compendium Yes 501 0.135 2555 337 0.132 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0019899 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZMYM2_ENST00000382871 ZMYM2 Q9UBW7 Zinc finger MYM-type protein 2 chr13 GO:0019899 Census Yes 144 0.105 583 68 0.117 0
ZNF346_ENST00000358149 ZNF346 Q9UL40 Zinc finger protein 346 chr5 GO:0019899 Not Cancer Driver No 29 0.099 175 17 0.097 0
ZNHIT6 ZNHIT6 Q9NWK9 Box C/D snoRNA protein 1 chr1 GO:0019899 Not Cancer Driver No 50 0.106 206 22 0.107 0
ZP1 ZP1 P60852 Zona pellucida sperm-binding protein 1 chr11 GO:0019899 Not Cancer Driver No 83 0.13 155 28 0.181 0
ZP2 ZP2 Q05996 Zona pellucida sperm-binding protein 2 chr16 GO:0019899 Not Cancer Driver No 129 0.173 65 14 0.215 0
ZP3 ZP3 P21754 Zona pellucida sperm-binding protein 3 chr7 GO:0019899 Not Cancer Driver No 55 0.13 56 11 0.196 1
ZP4 ZP4 Q12836 Zona pellucida sperm-binding protein 4 chr1 GO:0019899 Not Cancer Driver No 189 0.35 46 15 0.326 0