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Total number of protein in "GO:0018107" GO term:  73

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0018107 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0018107 Census, Compendium Yes 78 0.153 21 8 0.381 8
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0018107 Census, Compendium Yes 108 0.225 158 24 0.152 4
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0018107 Not Cancer Driver No 65 0.129 451 58 0.129 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0018107 Census, Compendium Yes 24 0.1 72 5 0.069 0
CAD CAD P27708 CAD protein chr2 GO:0018107 Not Cancer Driver No 287 0.129 368 52 0.141 1
CAMK2A_ENST00000348628 CAMK2A Q9UQM7 Calcium/calmodulin-dependent protein kinase type II subunit alpha chr5 GO:0018107 Not Cancer Driver No 83 0.174 62 10 0.161 7
CAMK2D_ENST00000342666 CAMK2D Q13557 Calcium/calmodulin-dependent protein kinase type II subunit delta chr4 GO:0018107 Not Cancer Driver No 57 0.114 84 10 0.119 0
CDC42BPA_ENST00000334218 CDC42BPA Q5VT25 Serine/threonine-protein kinase MRCK alpha chr1 GO:0018107 Not Cancer Driver No 215 0.124 717 80 0.112 0
CDC42BPB CDC42BPB Q9Y5S2 Serine/threonine-protein kinase MRCK beta chr14 GO:0018107 Not Cancer Driver No 185 0.108 696 92 0.132 0
CDC42BPG CDC42BPG Q6DT37 Serine/threonine-protein kinase MRCK gamma chr11 GO:0018107 Not Cancer Driver No 166 0.107 736 79 0.107 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0018107 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK10 CDK10 Q15131 Cyclin-dependent kinase 10 chr16 GO:0018107 Not Cancer Driver No 42 0.117 30 4 0.133 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0018107 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0018107 Not Cancer Driver No 35 0.114 103 16 0.155 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0018107 Not Cancer Driver No 58 0.122 86 16 0.186 0
CIT_ENST00000261833 CIT O14578 Citron Rho-interacting kinase chr12 GO:0018107 Not Cancer Driver No 284 0.14 1017 160 0.157 3
CLK1_ENST00000321356 CLK1 P49759 Dual specificity protein kinase CLK1 chr2 GO:0018107 Not Cancer Driver No 64 0.132 131 21 0.16 0
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0018107 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0018107 Not Cancer Driver No 43 0.123 13 1 0.077 0
CSNK2A3 CSNK2A3 Q8NEV1 Casein kinase II subunit alpha 3 chr11 GO:0018107 Not Cancer Driver No 66 0.169 75 10 0.133 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0018107 Not Cancer Driver No 20 0.093 19 0 0.0 4
DCAF1 DCAF1 Q9Y4B6 DDB1- and CUL4-associated factor 1 chr3 GO:0018107 Not Cancer Driver No 128 0.085 495 44 0.089 0
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0018107 Not Cancer Driver No 135 0.177 447 73 0.163 0
DYRK1B_ENST00000323039 DYRK1B Q9Y463 Dual specificity tyrosine-phosphorylation-regulated kinase 1B chr19 GO:0018107 Not Cancer Driver No 77 0.122 319 38 0.119 2
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0018107 Not Cancer Driver No 77 0.128 294 39 0.133 0
DYRK3 DYRK3 O43781 Dual specificity tyrosine-phosphorylation-regulated kinase 3 chr1 GO:0018107 Not Cancer Driver No 87 0.148 193 20 0.104 0
DYRK4_ENST00000010132 DYRK4 Q9NR20 Dual specificity tyrosine-phosphorylation-regulated kinase 4 chr12 GO:0018107 Not Cancer Driver No 111 0.213 178 33 0.185 0
GRK2 GRK2 P25098 Beta-adrenergic receptor kinase 1 chr11 GO:0018107 Not Cancer Driver No 77 0.112 87 8 0.092 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0018107 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0018107 Not Cancer Driver No 56 0.133 146 13 0.089 0
HASPIN HASPIN Q8TF76 Serine/threonine-protein kinase haspin chr17 GO:0018107 Not Cancer Driver No 87 0.109 373 36 0.097 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0018107 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0018107 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0018107 Not Cancer Driver No 128 0.105 559 51 0.091 0
HIPK4 HIPK4 Q8NE63 Homeodomain-interacting protein kinase 4 chr19 GO:0018107 Not Cancer Driver No 87 0.141 258 23 0.089 0
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 GO:0018107 Not Cancer Driver No 211 0.14 1018 141 0.139 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0018107 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0018107 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0018107 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0018107 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0018107 Not Cancer Driver No 64 0.15 94 9 0.096 0
MARK2 MARK2 Q7KZI7 Serine/threonine-protein kinase MARK2 chr11 GO:0018107 Compendium Yes 124 0.157 445 70 0.157 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0018107 Census, Compendium Yes 379 0.149 296 37 0.125 18
MYLK2 MYLK2 Q9H1R3 Myosin light chain kinase 2, skeletal/cardiac muscle chr20 GO:0018107 Not Cancer Driver No 118 0.198 277 64 0.231 2
NLK NLK Q9UBE8 Serine/threonine-protein kinase NLK chr17 GO:0018107 Not Cancer Driver No 54 0.102 152 20 0.132 0
OXSR1 OXSR1 O95747 Serine/threonine-protein kinase OSR1 chr3 GO:0018107 Not Cancer Driver No 69 0.131 208 29 0.139 0
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0018107 Not Cancer Driver No 33 0.059 121 12 0.099 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0018107 Not Cancer Driver No 120 0.127 459 54 0.118 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0018107 Census Yes 53 0.151 24 0 0.0 2
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0018107 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0018107 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0018107 Compendium Yes 79 0.117 43 9 0.209 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0018107 Census Yes 201 0.22 189 33 0.175 2
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0018107 Compendium Yes 118 0.134 246 34 0.138 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0018107 Not Cancer Driver No 538 0.13 421 61 0.145 2
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0018107 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0018107 Not Cancer Driver No 145 0.104 732 81 0.111 0
SBK1 SBK1 Q52WX2 Serine/threonine-protein kinase SBK1 chr16 GO:0018107 Not Cancer Driver No 41 0.097 139 6 0.043 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0018107 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0018107 Not Cancer Driver No 64 0.117 182 19 0.104 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0018107 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0018107 Not Cancer Driver No 101 0.139 42 5 0.119 12
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0018107 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0018107 Census, Compendium Yes 106 0.187 60 16 0.267 25
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0018107 Not Cancer Driver No 163 0.123 480 59 0.123 0
TSSK4_ENST00000287913 TSSK4 Q6SA08 Testis-specific serine/threonine-protein kinase 4 chr14 GO:0018107 Not Cancer Driver No 29 0.088 8 1 0.125 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0018107 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0018107 Not Cancer Driver No 136 0.159 352 46 0.131 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0018107 Not Cancer Driver No 142 0.135 588 77 0.131 0
VRK1 VRK1 Q99986 Serine/threonine-protein kinase VRK1 chr14 GO:0018107 Not Cancer Driver No 52 0.131 80 9 0.113 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0018107 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNK3_ENST00000375159 WNK3 Q9BYP7 Serine/threonine-protein kinase WNK3 chrX GO:0018107 Not Cancer Driver No 281 0.156 1281 200 0.156 0