Total number of protein in "GO:0010950" GO term: 60
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADRM1 | ADRM1 | Q16186 | Proteasomal ubiquitin receptor ADRM1 | chr20 | GO:0010950 | Not Cancer Driver | No | 49 | 0.12 | 296 | 40 | 0.135 | 0 |
| AGER_ENST00000375076 | AGER | Q15109 | Advanced glycosylation end product-specific receptor | chr6 | GO:0010950 | Not Cancer Driver | No | 31 | 0.077 | 297 | 21 | 0.071 | 0 |
| AKIRIN2 | AKIRIN2 | Q53H80 | Akirin-2 | chr6 | GO:0010950 | Not Cancer Driver | No | 21 | 0.103 | 119 | 11 | 0.092 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0010950 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| APH1A | APH1A | Q96BI3 | Gamma-secretase subunit APH-1A | chr1 | GO:0010950 | Not Cancer Driver | No | 32 | 0.121 | 0 | 0 | 0.0 | 0 |
| APH1B | APH1B | Q8WW43 | Gamma-secretase subunit APH-1B | chr15 | GO:0010950 | Not Cancer Driver | No | 21 | 0.082 | 0 | 0 | 0.0 | 0 |
| ASPH | ASPH | Q12797 | Aspartyl/asparaginyl beta-hydroxylase | chr8 | GO:0010950 | Not Cancer Driver | No | 109 | 0.144 | 373 | 53 | 0.142 | 1 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0010950 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0010950 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0010950 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0010950 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0010950 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0010950 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CIDEB | CIDEB | Q9UHD4 | Cell death activator CIDE-B | chr14 | GO:0010950 | Not Cancer Driver | No | 19 | 0.087 | 23 | 1 | 0.043 | 0 |
| CR1_ENST00000367053 | CR1 | P17927 | Complement receptor type 1 | chr1 | GO:0010950 | Compendium | Yes | 383 | 0.188 | 151 | 42 | 0.278 | 0 |
| CYCS_ENST00000409409 | CYCS | P99999 | Cytochrome c | chr7 | GO:0010950 | Not Cancer Driver | No | 12 | 0.114 | 19 | 3 | 0.158 | 1 |
| CYFIP2 | CYFIP2 | Q96F07 | Cytoplasmic FMR1-interacting protein 2 | chr5 | GO:0010950 | Not Cancer Driver | No | 211 | 0.165 | 86 | 11 | 0.128 | 3 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0010950 | Not Cancer Driver | No | 62 | 0.259 | 54 | 8 | 0.148 | 1 |
| EFNA1 | EFNA1 | P20827 | Ephrin-A1 | chr1 | GO:0010950 | Not Cancer Driver | No | 29 | 0.141 | 46 | 5 | 0.109 | 0 |
| EFNA3 | EFNA3 | P52797 | Ephrin-A3 | chr1 | GO:0010950 | Not Cancer Driver | No | 24 | 0.101 | 31 | 11 | 0.355 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0010950 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0010950 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FAS | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0010950 | Census, Compendium | Yes | 55 | 0.164 | 62 | 18 | 0.29 | 22 |
| GRIN2A_ENST00000330684 | GRIN2A | Q12879 | Glutamate receptor ionotropic, NMDA 2A | chr16 | GO:0010950 | Census, Compendium | Yes | 528 | 0.361 | 506 | 207 | 0.409 | 31 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0010950 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0010950 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | GO:0010950 | Not Cancer Driver | No | 155 | 0.197 | 419 | 90 | 0.215 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0010950 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| LGALS9 | LGALS9 | O00182 | Galectin-9 | chr17 | GO:0010950 | Not Cancer Driver | No | 54 | 0.152 | 65 | 16 | 0.246 | 0 |
| LGMN_ENST00000334869 | LGMN | Q99538 | Legumain | chr14 | GO:0010950 | Not Cancer Driver | No | 57 | 0.132 | 112 | 19 | 0.17 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0010950 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MBP_ENST00000580402 | MBP | P02686 | Myelin basic protein | chr18 | GO:0010950 | Not Cancer Driver | No | 52 | 0.171 | 304 | 52 | 0.171 | 0 |
| NCSTN | NCSTN | Q92542 | Nicastrin | chr1 | GO:0010950 | Not Cancer Driver | No | 94 | 0.133 | 72 | 11 | 0.153 | 1 |
| NLRC4_ENST00000360906 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0010950 | Not Cancer Driver | No | 205 | 0.2 | 15 | 2 | 0.133 | 3 |
| NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0010950 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
| PERP | PERP | Q96FX8 | p53 apoptosis effector related to PMP-22 | chr6 | GO:0010950 | Not Cancer Driver | No | 28 | 0.145 | 0 | 0 | 0.0 | 1 |
| PICALM | PICALM | Q13492 | Phosphatidylinositol-binding clathrin assembly protein | chr11 | GO:0010950 | Census | Yes | 89 | 0.137 | 320 | 42 | 0.131 | 0 |
| PRELID1 | PRELID1 | Q9Y255 | PRELI domain-containing protein 1, mitochondrial | chr5 | GO:0010950 | Not Cancer Driver | No | 21 | 0.096 | 44 | 2 | 0.045 | 0 |
| PRR7_ENST00000502922 | PRR7 | Q8TB68 | Proline-rich protein 7 | chr5 | GO:0010950 | Not Cancer Driver | No | 10 | 0.036 | 199 | 6 | 0.03 | 0 |
| PSENEN_ENST00000222266 | PSENEN | Q9NZ42 | Gamma-secretase subunit PEN-2 | chr19 | GO:0010950 | Not Cancer Driver | No | 17 | 0.168 | 0 | 0 | 0.0 | 0 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | GO:0010950 | Not Cancer Driver | No | 23 | 0.074 | 67 | 6 | 0.09 | 0 |
| PSME1_ENST00000206451 | PSME1 | Q06323 | Proteasome activator complex subunit 1 | chr14 | GO:0010950 | Not Cancer Driver | No | 20 | 0.08 | 80 | 8 | 0.1 | 0 |
| PSME2 | PSME2 | Q9UL46 | Proteasome activator complex subunit 2 | chr14 | GO:0010950 | Not Cancer Driver | No | 32 | 0.134 | 39 | 3 | 0.077 | 0 |
| PSME3_ENST00000590720 | PSME3 | P61289 | Proteasome activator complex subunit 3 | chr17 | GO:0010950 | Not Cancer Driver | No | 20 | 0.079 | 25 | 5 | 0.2 | 0 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0010950 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RFPL1 | RFPL1 | O75677 | Ret finger protein-like 1 | chr22 | GO:0010950 | Not Cancer Driver | No | 73 | 0.23 | 28 | 5 | 0.179 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0010950 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| ROCK2 | ROCK2 | O75116 | Rho-associated protein kinase 2 | chr2 | GO:0010950 | Not Cancer Driver | No | 145 | 0.104 | 732 | 81 | 0.111 | 0 |
| RPS3_ENST00000527446 | RPS3 | P23396 | 40S ribosomal protein S3 | chr11 | GO:0010950 | Not Cancer Driver | No | 22 | 0.091 | 48 | 4 | 0.083 | 0 |
| SEMG1 | SEMG1 | P04279 | Semenogelin-1 | chr20 | GO:0010950 | Not Cancer Driver | No | 101 | 0.219 | 442 | 98 | 0.222 | 0 |
| SEMG2 | SEMG2 | Q02383 | Semenogelin-2 | chr20 | GO:0010950 | Not Cancer Driver | No | 147 | 0.253 | 561 | 145 | 0.258 | 0 |
| SERPINB3 | SERPINB3 | P29508 | Serpin B3 | chr18 | GO:0010950 | Not Cancer Driver | No | 142 | 0.364 | 47 | 28 | 0.596 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0010950 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0010950 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| ST18 | ST18 | O60284 | Suppression of tumorigenicity 18 protein | chr8 | GO:0010950 | Not Cancer Driver | No | 330 | 0.315 | 820 | 282 | 0.344 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0010950 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| TBC1D10A_ENST00000215790 | TBC1D10A | Q9BXI6 | TBC1 domain family member 10A | chr22 | GO:0010950 | Not Cancer Driver | No | 72 | 0.142 | 209 | 26 | 0.124 | 0 |
| TFAP4 | TFAP4 | Q01664 | Transcription factor AP-4 | chr16 | GO:0010950 | Compendium | Yes | 61 | 0.18 | 285 | 52 | 0.182 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0010950 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| VSIR | VSIR | Q9H7M9 | V-type immunoglobulin domain-containing suppressor of T-cell activation | chr10 | GO:0010950 | Not Cancer Driver | No | 52 | 0.167 | 135 | 19 | 0.141 | 0 |