Filter in search result
Please select a valid state.

Total number of protein in "GO:0010638" GO term:  418

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0010638 Not Cancer Driver No 56 0.109 361 38 0.105 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0010638 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0010638 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACTN2_ENST00000366578 ACTN2 P35609 Alpha-actinin-2 chr1 GO:0010638 Not Cancer Driver No 227 0.254 131 29 0.221 9
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 GO:0010638 Not Cancer Driver No 82 0.155 6 3 0.5 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0010638 Not Cancer Driver No 52 0.126 35 4 0.114 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0010638 Census Yes 474 0.121 2281 268 0.117 1
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0010638 Census Yes 77 0.16 84 9 0.107 2
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0010638 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANAPC11_ENST00000579978 ANAPC11 Q9NYG5 Anaphase-promoting complex subunit 11 chr17 GO:0010638 Not Cancer Driver No 7 0.083 0 0 0.0 0
ANAPC4_ENST00000315368 ANAPC4 Q9UJX5 Anaphase-promoting complex subunit 4 chr4 GO:0010638 Not Cancer Driver No 70 0.087 54 1 0.019 0
ANAPC5 ANAPC5 Q9UJX4 Anaphase-promoting complex subunit 5 chr12 GO:0010638 Not Cancer Driver No 94 0.125 41 4 0.098 0
ANKRD53 ANKRD53 Q8N9V6 Ankyrin repeat domain-containing protein 53 chr2 GO:0010638 Not Cancer Driver No 57 0.108 252 21 0.083 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0010638 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA2_ENST00000396024 ANXA2 P07355 Annexin A2 chr15 GO:0010638 Not Cancer Driver No 49 0.145 20 4 0.2 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0010638 Not Cancer Driver No 28 0.105 131 8 0.061 3
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0010638 Census, Compendium Yes 255 0.17 409 58 0.142 0
ARHGEF10L ARHGEF10L Q9HCE6 Rho guanine nucleotide exchange factor 10-like protein chr1 GO:0010638 Census, Compendium Yes 155 0.121 431 47 0.109 0
ARHGEF10_ENST00000398564 ARHGEF10 O15013 Rho guanine nucleotide exchange factor 10 chr8 GO:0010638 Census, Compendium Yes 175 0.128 586 78 0.133 1
ARHGEF15 ARHGEF15 O94989 Rho guanine nucleotide exchange factor 15 chr17 GO:0010638 Not Cancer Driver No 156 0.185 536 97 0.181 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0010638 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARL2 ARL2 P36404 ADP-ribosylation factor-like protein 2 chr11 GO:0010638 Not Cancer Driver No 19 0.103 0 0 0.0 1
ARL3 ARL3 P36405 ADP-ribosylation factor-like protein 3 chr10 GO:0010638 Not Cancer Driver No 16 0.088 0 0 0.0 2
ASAP1 ASAP1 Q9ULH1 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 chr8 GO:0010638 Not Cancer Driver No 183 0.162 584 108 0.185 0
ATF7IP2_ENST00000356427 ATF7IP2 Q5U623 Activating transcription factor 7-interacting protein 2 chr16 GO:0010638 Not Cancer Driver No 89 0.13 456 66 0.145 0
ATF7IP_ENST00000540793 ATF7IP Q6VMQ6 Activating transcription factor 7-interacting protein 1 chr12 GO:0010638 Compendium Yes 160 0.126 1136 139 0.122 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 GO:0010638 Not Cancer Driver No 228 0.118 887 124 0.14 0
ATL3 ATL3 Q6DD88 Atlastin-3 chr11 GO:0010638 Not Cancer Driver No 43 0.079 57 5 0.088 1
ATMIN ATMIN O43313 ATM interactor chr16 GO:0010638 Not Cancer Driver No 85 0.103 466 40 0.086 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0010638 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP5IF1 ATP5IF1 Q9UII2 ATPase inhibitor, mitochondrial chr1 GO:0010638 Not Cancer Driver No 8 0.075 85 7 0.082 0
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0010638 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0010638 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0010638 Not Cancer Driver No 36 0.089 178 21 0.118 0
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0010638 Not Cancer Driver No 51 0.148 63 8 0.127 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0010638 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0010638 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0010638 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAIAP2L1 BAIAP2L1 Q9UHR4 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 chr7 GO:0010638 Not Cancer Driver No 76 0.149 293 42 0.143 0
BAIAP2L2 BAIAP2L2 Q6UXY1 Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 chr22 GO:0010638 Not Cancer Driver No 41 0.078 338 24 0.071 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0010638 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0010638 Not Cancer Driver No 20 0.077 253 20 0.079 0
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0010638 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0010638 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0010638 Not Cancer Driver No 42 0.212 130 17 0.131 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0010638 Not Cancer Driver No 45 0.1 190 19 0.1 0
BHMG1 MEIOSIN C9JSJ3 Meiosis initiator protein chr19 GO:0010638 Not Cancer Driver No 0 0.0 498 0 0.0 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0010638 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIK BIK Q13323 Bcl-2-interacting killer chr22 GO:0010638 Not Cancer Driver No 16 0.1 21 4 0.19 0
BMF_ENST00000561360 BMF Q96LC9 Bcl-2-modifying factor chr15 GO:0010638 Not Cancer Driver No 22 0.12 94 9 0.096 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0010638 Not Cancer Driver No 88 0.208 87 13 0.149 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0010638 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRK1 BRK1 Q8WUW1 Protein BRICK1 chr3 GO:0010638 Not Cancer Driver No 7 0.093 14 1 0.071 0
C2CD5_ENST00000333957 C2CD5 Q86YS7 C2 domain-containing protein 5 chr12 GO:0010638 Not Cancer Driver No 136 0.136 250 40 0.16 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 GO:0010638 Not Cancer Driver No 42 0.094 212 19 0.09 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0010638 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0010638 Not Cancer Driver No 45 0.129 95 7 0.074 0
CARMIL1 CARMIL1 Q5VZK9 F-actin-uncapping protein LRRC16A chr6 GO:0010638 Not Cancer Driver No 171 0.125 537 87 0.162 0
CARMIL2 CARMIL2 Q6F5E8 Capping protein, Arp2/3 and myosin-I linker protein 2 chr16 GO:0010638 Not Cancer Driver No 154 0.107 669 75 0.112 4
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0010638 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0010638 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL27 CCL27 Q9Y4X3 C-C motif chemokine 27 chr9 GO:0010638 Not Cancer Driver No 15 0.134 0 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0010638 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCP110 CCP110 O43303 Centriolar coiled-coil protein of 110 kDa chr16 GO:0010638 Not Cancer Driver No 94 0.093 679 61 0.09 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0010638 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0010638 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0010638 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0010638 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0010638 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0010638 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0010638 Not Cancer Driver No 41 0.075 36 2 0.056 0
CD47 CD47 Q08722 Leukocyte surface antigen CD47 chr3 GO:0010638 Not Cancer Driver No 37 0.115 0 0 0.0 0
CDC16_ENST00000356221 CDC16 Q13042 Cell division cycle protein 16 homolog chr13 GO:0010638 Not Cancer Driver No 68 0.11 54 7 0.13 0
CDC23 CDC23 Q9UJX2 Cell division cycle protein 23 homolog chr5 GO:0010638 Not Cancer Driver No 57 0.095 45 6 0.133 0
CDC27_ENST00000066544 CDC27 P30260 Cell division cycle protein 27 homolog chr17 GO:0010638 Not Cancer Driver No 179 0.217 289 75 0.26 0
CDC42_ENST00000344548 CDC42 P60953 Cell division control protein 42 homolog chr1 GO:0010638 Not Cancer Driver No 39 0.204 23 2 0.087 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0010638 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0010638 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0010638 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0010638 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0010638 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0010638 Not Cancer Driver No 60 0.11 377 35 0.093 5
CENPJ CENPJ Q9HC77 Centromere protein J chr13 GO:0010638 Not Cancer Driver No 176 0.132 1176 158 0.134 1
CEP120 CEP120 Q8N960 Centrosomal protein of 120 kDa chr5 GO:0010638 Not Cancer Driver No 102 0.103 448 52 0.116 1
CEP135 CEP135 Q66GS9 Centrosomal protein of 135 kDa chr4 GO:0010638 Not Cancer Driver No 127 0.111 690 72 0.104 0
CEP295 CEP295 Q9C0D2 Centrosomal protein of 295 kDa chr11 GO:0010638 Not Cancer Driver No 115 0.044 2026 87 0.043 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0010638 Not Cancer Driver No 29 0.083 19 0 0.0 1
CFL2_ENST00000341223 CFL2 Q9Y281 Cofilin-2 chr14 GO:0010638 Not Cancer Driver No 25 0.151 0 0 0.0 1
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0010638 Not Cancer Driver No 8 0.056 97 4 0.041 4
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0010638 Not Cancer Driver No 19 0.087 23 1 0.043 0
CKAP5 CKAP5 Q14008 Cytoskeleton-associated protein 5 chr11 GO:0010638 Not Cancer Driver No 198 0.097 634 64 0.101 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0010638 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLIP1 CLIP1 P30622 CAP-Gly domain-containing linker protein 1 chr12 GO:0010638 Census, Compendium Yes 184 0.128 1194 136 0.114 0
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0010638 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT2 CNOT2 Q9NZN8 CCR4-NOT transcription complex subunit 2 chr12 GO:0010638 Not Cancer Driver No 84 0.156 354 66 0.186 0
CNOT6L CNOT6L Q96LI5 CCR4-NOT transcription complex subunit 6-like chr4 GO:0010638 Not Cancer Driver No 58 0.105 37 3 0.081 0
CNOT6_ENST00000261951 CNOT6 Q9ULM6 CCR4-NOT transcription complex subunit 6 chr5 GO:0010638 Not Cancer Driver No 65 0.117 66 4 0.061 0
CROCC CROCC Q5TZA2 Rootletin chr1 GO:0010638 Not Cancer Driver No 254 0.126 1583 184 0.116 0
CSF2 CSF2 P04141 Granulocyte-macrophage colony-stimulating factor chr5 GO:0010638 Not Cancer Driver No 11 0.076 34 3 0.088 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0010638 Not Cancer Driver No 20 0.097 7 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0010638 Census, Compendium Yes 415 0.531 288 301 1.045 14
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0010638 Census, Compendium Yes 123 0.16 167 23 0.138 3
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0010638 Not Cancer Driver No 66 0.166 259 44 0.17 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0010638 Not Cancer Driver No 46 0.037 96 0 0.0 0
DCN DCN P07585 Decorin chr12 GO:0010638 Not Cancer Driver No 96 0.267 81 26 0.321 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0010638 Census Yes 172 0.135 817 111 0.136 11
DDHD1 DDHD1 Q8NEL9 Phospholipase DDHD1 chr14 GO:0010638 Not Cancer Driver No 120 0.133 393 40 0.102 0
DDHD2_ENST00000520272 DDHD2 O94830 Phospholipase DDHD2 chr8 GO:0010638 Not Cancer Driver No 95 0.134 169 25 0.148 1
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0010638 Not Cancer Driver No 154 0.159 280 55 0.196 1
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0010638 Not Cancer Driver No 159 0.158 222 39 0.176 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0010638 Not Cancer Driver No 62 0.121 145 29 0.2 24
DLGAP5 DLGAP5 Q15398 Disks large-associated protein 5 chr14 GO:0010638 Not Cancer Driver No 84 0.099 676 70 0.104 0
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0010638 Not Cancer Driver No 60 0.161 282 47 0.167 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0010638 Not Cancer Driver No 67 0.091 212 23 0.108 7
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0010638 Not Cancer Driver No 203 0.126 702 78 0.111 4
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0010638 Not Cancer Driver No 10 0.024 197 3 0.015 0
DRG1 DRG1 Q9Y295 Developmentally-regulated GTP-binding protein 1 chr22 GO:0010638 Not Cancer Driver No 35 0.095 31 0 0.0 0
DSTN DSTN P60981 Destrin chr20 GO:0010638 Not Cancer Driver No 18 0.109 0 0 0.0 0
DYNC1H1 DYNC1H1 Q14204 Cytoplasmic dynein 1 heavy chain 1 chr14 GO:0010638 Not Cancer Driver No 505 0.109 495 62 0.125 21
DZIP1_ENST00000376829 DZIP1 Q86YF9 Cilium assembly protein DZIP1 chr13 GO:0010638 Not Cancer Driver No 143 0.165 523 92 0.176 2
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0010638 Not Cancer Driver No 37 0.175 97 20 0.206 3
ENTR1 ENTR1 Q96C92 Endosome-associated-trafficking regulator 1 chr9 GO:0010638 Not Cancer Driver No 64 0.147 267 38 0.142 0
EPHA1 EPHA1 P21709 Ephrin type-A receptor 1 chr7 GO:0010638 Not Cancer Driver No 147 0.151 211 38 0.18 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0010638 Not Cancer Driver No 42 0.141 105 14 0.133 1
ESPL1 ESPL1 Q14674 Separin chr12 GO:0010638 Not Cancer Driver No 211 0.1 380 39 0.103 0
EVL_ENST00000402714 EVL Q9UI08 Ena/VASP-like protein chr14 GO:0010638 Not Cancer Driver No 42 0.101 335 37 0.11 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0010638 Not Cancer Driver No 55 0.139 7 2 0.286 0
FAM162A FAM162A Q96A26 Protein FAM162A chr3 GO:0010638 Not Cancer Driver No 18 0.117 53 8 0.151 0
FAM208A_ENST00000355628 TASOR Q9UK61 Protein TASOR chr3 GO:0010638 Not Cancer Driver No 150 0.09 776 68 0.088 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0010638 Not Cancer Driver No 55 0.142 68 7 0.103 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0010638 Not Cancer Driver No 75 0.144 243 38 0.156 1
FCHSD2 FCHSD2 O94868 F-BAR and double SH3 domains protein 2 chr11 GO:0010638 Not Cancer Driver No 61 0.082 391 30 0.077 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0010638 Census Yes 35 0.092 111 11 0.099 0
FERMT2_ENST00000395631 FERMT2 Q96AC1 Fermitin family homolog 2 chr14 GO:0010638 Not Cancer Driver No 71 0.104 101 10 0.099 0
FES FES P07332 Tyrosine-protein kinase Fes/Fps chr15 GO:0010638 Census Yes 103 0.125 245 34 0.139 0
FHOD1 FHOD1 Q9Y613 FH1/FH2 domain-containing protein 1 chr16 GO:0010638 Not Cancer Driver No 151 0.13 575 82 0.143 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0010638 Not Cancer Driver No 25 0.164 6 0 0.0 0
FMN1 FMN1 Q68DA7 Formin-1 chr15 GO:0010638 Not Cancer Driver No 117 0.082 983 67 0.068 0
FSCN1 FSCN1 Q16658 Fascin chr7 GO:0010638 Not Cancer Driver No 58 0.118 81 5 0.062 0
FUZ FUZ Q9BT04 Protein fuzzy homolog chr19 GO:0010638 Not Cancer Driver No 38 0.091 43 4 0.093 0
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 GO:0010638 Not Cancer Driver No 181 0.122 892 106 0.119 1
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0010638 Not Cancer Driver No 85 0.182 352 65 0.185 0
G3BP2_ENST00000395719 G3BP2 Q9UN86 Ras GTPase-activating protein-binding protein 2 chr4 GO:0010638 Not Cancer Driver No 64 0.133 384 53 0.138 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0010638 Not Cancer Driver No 67 0.088 434 42 0.097 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0010638 Not Cancer Driver No 56 0.102 257 21 0.082 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0010638 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0010638 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPSM2_ENST00000642355 GPSM2 P81274 G-protein-signaling modulator 2 chr1 GO:0010638 Not Cancer Driver No 79 0.115 240 21 0.087 0
GRN GRN P28799 Progranulin chr17 GO:0010638 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0010638 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0010638 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSN GSN P06396 Gelsolin chr9 GO:0010638 Not Cancer Driver No 76 0.097 316 28 0.089 2
GTF2H2_ENST00000330280 GTF2H2 Q13888 General transcription factor IIH subunit 2 chr5 GO:0010638 Not Cancer Driver No 7 0.018 43 1 0.023 0
GZMB GZMB P10144 Granzyme B chr14 GO:0010638 Not Cancer Driver No 49 0.198 103 23 0.223 0
H2AFY MACROH2A1 O75367 Core histone macro-H2A.1 chr5 GO:0010638 Not Cancer Driver No 46 0.124 125 19 0.152 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0010638 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0010638 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCK_ENST00000534862 HCK P08631 Tyrosine-protein kinase HCK chr20 GO:0010638 Not Cancer Driver No 112 0.213 124 25 0.202 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0010638 Not Cancer Driver No 103 0.212 446 94 0.211 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0010638 Census Yes 118 0.143 435 51 0.117 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0010638 Not Cancer Driver No 94 0.088 524 34 0.065 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0010638 Not Cancer Driver No 55 0.131 319 41 0.129 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0010638 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPA2B1 HNRNPA2B1 P22626 Heterogeneous nuclear ribonucleoproteins A2/B1 chr7 GO:0010638 Census, Compendium Yes 68 0.193 255 41 0.161 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0010638 Not Cancer Driver No 39 0.11 206 19 0.092 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0010638 Census, Compendium Yes 107 0.566 16 4 0.25 18
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0010638 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0010638 Not Cancer Driver No 15 0.023 200 5 0.025 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0010638 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0010638 Not Cancer Driver No 336 0.107 666 69 0.104 2
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0010638 Not Cancer Driver No 20 0.129 17 6 0.353 0
IL5 IL5 P05113 Interleukin-5 chr5 GO:0010638 Not Cancer Driver No 13 0.097 0 0 0.0 0
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0010638 Not Cancer Driver No 9 0.05 45 1 0.022 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0010638 Not Cancer Driver No 26 0.13 58 11 0.19 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 GO:0010638 Not Cancer Driver No 70 0.107 179 24 0.134 3
KCTD17 KCTD17 Q8N5Z5 BTB/POZ domain-containing protein KCTD17 chr22 GO:0010638 Not Cancer Driver No 23 0.072 187 14 0.075 1
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0010638 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIAA1211 CRACD Q6ZU35 Capping protein-inhibiting regulator of actin dynamics chr4 GO:0010638 Not Cancer Driver No 245 0.199 1210 241 0.199 0
KIAA1324 ELAPOR1 Q6UXG2 Endosome/lysosome-associated apoptosis and autophagy regulator 1 chr1 GO:0010638 Not Cancer Driver No 94 0.093 56 5 0.089 0
LCP1 LCP1 P13796 Plastin-2 chr13 GO:0010638 Census Yes 99 0.158 73 11 0.151 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0010638 Not Cancer Driver No 134 0.147 63 10 0.159 2
LIMCH1_ENST00000313860 LIMCH1 Q9UPQ0 LIM and calponin homology domains-containing protein 1 chr4 GO:0010638 Not Cancer Driver No 177 0.163 880 140 0.159 0
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0010638 Not Cancer Driver No 110 0.17 170 30 0.176 0
LMAN1 LMAN1 P49257 Protein ERGIC-53 chr18 GO:0010638 Not Cancer Driver No 63 0.124 222 25 0.113 1
LNPK_ENST00000272748 LNPK Q9C0E8 Endoplasmic reticulum junction formation protein lunapark chr2 GO:0010638 Not Cancer Driver No 62 0.145 257 43 0.167 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0010638 Not Cancer Driver No 79 0.217 21 6 0.286 0
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0010638 Not Cancer Driver No 86 0.119 240 30 0.125 1
MAD2L1BP_ENST00000372171 MAD2L1BP Q15013 MAD2L1-binding protein chr6 GO:0010638 Not Cancer Driver No 26 0.095 55 7 0.127 0
MAGEL2 MAGEL2 Q9UJ55 MAGE-like protein 2 chr15 GO:0010638 Not Cancer Driver No 178 0.143 1010 118 0.117 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0010638 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0010638 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0010638 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0010638 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0010638 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0010638 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0010638 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0010638 Not Cancer Driver No 59 0.139 90 8 0.089 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0010638 Not Cancer Driver No 51 0.108 101 12 0.119 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0010638 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0010638 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARCH5 MARCHF5 Q9NX47 E3 ubiquitin-protein ligase MARCHF5 chr10 GO:0010638 Not Cancer Driver No 27 0.097 0 0 0.0 0
MARK4 MARK4 Q96L34 MAP/microtubule affinity-regulating kinase 4 chr19 GO:0010638 Not Cancer Driver No 94 0.125 403 46 0.114 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0010638 Not Cancer Driver No 41 0.117 13 0 0.0 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0010638 Not Cancer Driver No 75 0.154 483 74 0.153 46
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0010638 Census, Compendium Yes 226 0.163 62 15 0.242 19
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 GO:0010638 Not Cancer Driver No 59 0.173 264 47 0.178 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0010638 Not Cancer Driver No 25 0.104 207 22 0.106 0
MIEF1_ENST00000404569 MIEF1 Q9NQG6 Mitochondrial dynamics protein MID51 chr22 GO:0010638 Not Cancer Driver No 65 0.14 94 9 0.096 0
MIEF2_ENST00000323019 MIEF2 Q96C03 Mitochondrial dynamics protein MID49 chr17 GO:0010638 Not Cancer Driver No 43 0.095 89 9 0.101 0
MLLT11 MLLT11 Q13015 Protein AF1q chr1 GO:0010638 Census Yes 15 0.167 18 5 0.278 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0010638 Not Cancer Driver No 129 0.182 124 26 0.21 0
MNS1 MNS1 Q8NEH6 Meiosis-specific nuclear structural protein 1 chr15 GO:0010638 Not Cancer Driver No 47 0.095 327 32 0.098 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0010638 Not Cancer Driver No 48 0.137 47 8 0.17 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 GO:0010638 Not Cancer Driver No 125 0.121 523 69 0.132 16
MPHOSPH8 MPHOSPH8 Q99549 M-phase phosphoprotein 8 chr13 GO:0010638 Not Cancer Driver No 105 0.122 523 66 0.126 0
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0010638 Not Cancer Driver No 84 0.119 292 35 0.12 1
MSN MSN P26038 Moesin chrX GO:0010638 Census, Compendium Yes 108 0.187 286 56 0.196 1
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0010638 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0010638 Not Cancer Driver No 27 0.101 168 14 0.083 4
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0010638 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTSS1_ENST00000518547 MTSS1 O43312 Protein MTSS 1 chr8 GO:0010638 Not Cancer Driver No 107 0.142 584 86 0.147 0
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0010638 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYLK3 MYLK3 Q32MK0 Myosin light chain kinase 3 chr16 GO:0010638 Not Cancer Driver No 163 0.199 469 83 0.177 0
MYOC MYOC Q99972 Myocilin chr1 GO:0010638 Not Cancer Driver No 92 0.183 196 43 0.219 58
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0010638 Not Cancer Driver No 25 0.118 125 17 0.136 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0010638 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0010638 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NBN NBN O60934 Nibrin chr8 GO:0010638 Census Yes 90 0.119 417 54 0.129 1
NCAPD2 NCAPD2 Q15021 Condensin complex subunit 1 chr12 GO:0010638 Not Cancer Driver No 124 0.089 345 35 0.101 0
NCAPG NCAPG Q9BPX3 Condensin complex subunit 3 chr4 GO:0010638 Not Cancer Driver No 85 0.084 154 13 0.084 0
NCAPH NCAPH Q15003 Condensin complex subunit 2 chr2 GO:0010638 Not Cancer Driver No 97 0.131 465 60 0.129 1
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0010638 Not Cancer Driver No 129 0.114 44 3 0.068 0
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0010638 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0010638 Not Cancer Driver No 35 0.116 23 0 0.0 0
NES NES P48681 Nestin chr1 GO:0010638 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NF2 NF2 P35240 Merlin chr22 GO:0010638 Census, Compendium Yes 69 0.116 252 26 0.103 16
NIN NIN Q8N4C6 Ninein chr14 GO:0010638 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NMT1_ENST00000258960 NMT1 P30419 Glycylpeptide N-tetradecanoyltransferase 1 chr17 GO:0010638 Not Cancer Driver No 62 0.125 169 22 0.13 0
NPM2_ENST00000518119 NPM2 Q86SE8 Nucleoplasmin-2 chr8 GO:0010638 Not Cancer Driver No 25 0.117 165 21 0.127 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0010638 Compendium Yes 146 0.158 211 31 0.147 0
NSMCE2_ENST00000522563 NSMCE2 Q96MF7 E3 SUMO-protein ligase NSE2 chr8 GO:0010638 Not Cancer Driver No 30 0.121 119 12 0.101 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0010638 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0010638 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0010638 Census, Compendium Yes 234 0.111 1864 203 0.109 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0010638 Not Cancer Driver No 76 0.146 377 56 0.149 1
OCLN OCLN Q16625 Occludin chr5 GO:0010638 Not Cancer Driver No 54 0.103 244 21 0.086 1
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0010638 Not Cancer Driver No 46 0.309 48 14 0.292 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0010638 Not Cancer Driver No 83 0.103 386 39 0.101 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0010638 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAN2_ENST00000548043 PAN2 Q504Q3 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 chr12 GO:0010638 Not Cancer Driver No 139 0.116 78 10 0.128 0
PAN3 PAN3 Q58A45 PAN2-PAN3 deadenylation complex subunit PAN3 chr13 GO:0010638 Not Cancer Driver No 104 0.117 323 35 0.108 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0010638 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0010638 Not Cancer Driver No 71 0.111 197 22 0.112 2
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 GO:0010638 Not Cancer Driver No 15 0.12 91 7 0.077 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0010638 Not Cancer Driver No 85 0.098 272 22 0.081 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0010638 Not Cancer Driver No 14 0.047 38 4 0.105 0
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0010638 Not Cancer Driver No 16 0.114 7 1 0.143 3
PFN2 PFN2 P35080 Profilin-2 chr3 GO:0010638 Not Cancer Driver No 20 0.143 0 0 0.0 0
PFN3 PFN3 P60673 Profilin-3 chr5 GO:0010638 Not Cancer Driver No 8 0.058 0 0 0.0 0
PGAM5 PGAM5 Q96HS1 Serine/threonine-protein phosphatase PGAM5, mitochondrial chr12 GO:0010638 Not Cancer Driver No 32 0.111 102 12 0.118 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0010638 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0010638 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0010638 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIWIL2_ENST00000454009 PIWIL2 Q8TC59 Piwi-like protein 2 chr8 GO:0010638 Not Cancer Driver No 138 0.142 232 38 0.164 0
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0010638 Not Cancer Driver No 13 0.167 78 13 0.167 0
PLA2G5 PLA2G5 P39877 Phospholipase A2 group V chr1 GO:0010638 Not Cancer Driver No 24 0.174 0 0 0.0 2
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0010638 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0010638 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0010638 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLD6 PLD6 Q8N2A8 Mitochondrial cardiolipin hydrolase chr17 GO:0010638 Not Cancer Driver No 27 0.107 24 6 0.25 0
PLEK PLEK P08567 Pleckstrin chr2 GO:0010638 Not Cancer Driver No 81 0.231 39 9 0.231 0
PLK4 PLK4 O00444 Serine/threonine-protein kinase PLK4 chr4 GO:0010638 Not Cancer Driver No 102 0.105 451 45 0.1 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0010638 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0010638 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0010638 Not Cancer Driver No 53 0.102 177 23 0.13 4
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0010638 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0010638 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPHLN1_ENST00000610488 PPHLN1 Q8NEY8 Periphilin-1 chr12 GO:0010638 Not Cancer Driver No 64 0.14 447 62 0.139 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0010638 Not Cancer Driver No 19 0.092 43 4 0.093 0
PPM1E PPM1E Q8WY54 Protein phosphatase 1E chr17 GO:0010638 Not Cancer Driver No 114 0.151 384 53 0.138 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0010638 Not Cancer Driver No 53 0.117 242 24 0.099 0
PPP1R10 PPP1R10 Q96QC0 Serine/threonine-protein phosphatase 1 regulatory subunit 10 chr6 GO:0010638 Not Cancer Driver No 114 0.121 798 100 0.125 0
PPP1R35 PPP1R35 Q8TAP8 Protein phosphatase 1 regulatory subunit 35 chr7 GO:0010638 Not Cancer Driver No 19 0.075 207 15 0.072 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0010638 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM7_ENST00000449207 PRDM7 Q9NQW5 Histone-lysine N-methyltransferase PRDM7 chr16 GO:0010638 Not Cancer Driver No 62 0.126 280 26 0.093 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0010638 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0010638 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0010638 Not Cancer Driver No 110 0.237 78 15 0.192 31
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0010638 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0010638 Not Cancer Driver No 45 0.132 268 32 0.119 7
PSRC1_ENST00000409138 PSRC1 Q6PGN9 Proline/serine-rich coiled-coil protein 1 chr1 GO:0010638 Not Cancer Driver No 30 0.083 361 30 0.083 0
PXN_ENST00000228307 PXN P49023 Paxillin chr12 GO:0010638 Not Cancer Driver No 62 0.105 341 24 0.07 0
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0010638 Not Cancer Driver No 16 0.082 39 4 0.103 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0010638 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0010638 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0010638 Census, Compendium Yes 66 0.344 2 1 0.5 6
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0010638 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0010638 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0010638 Not Cancer Driver No 46 0.131 335 43 0.128 0
RALA RALA P11233 Ras-related protein Ral-A chr7 GO:0010638 Not Cancer Driver No 34 0.165 34 3 0.088 5
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0010638 Not Cancer Driver No 36 0.175 35 5 0.143 0
RALBP1 RALBP1 Q15311 RalA-binding protein 1 chr18 GO:0010638 Not Cancer Driver No 65 0.099 381 46 0.121 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0010638 Not Cancer Driver No 97 0.105 197 19 0.096 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0010638 Census, Compendium Yes 140 0.151 282 32 0.113 22
RESF1 RESF1 Q9HCM1 Retroelement silencing factor 1 chr12 GO:0010638 Not Cancer Driver No 217 0.124 1528 185 0.121 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0010638 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0010638 Census, Compendium Yes 99 0.513 46 13 0.283 2
RHOC_ENST00000369642 RHOC P08134 Rho-related GTP-binding protein RhoC chr1 GO:0010638 Not Cancer Driver No 30 0.155 53 7 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0010638 Not Cancer Driver No 145 0.104 732 81 0.111 0
RP1 RP1 P56715 Oxygen-regulated protein 1 chr8 GO:0010638 Not Cancer Driver No 737 0.342 1215 441 0.363 6
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0010638 Not Cancer Driver No 22 0.091 48 4 0.083 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0010638 Not Cancer Driver No 144 0.118 474 64 0.135 14
S100A10 S100A10 P60903 Protein S100-A10 chr1 GO:0010638 Not Cancer Driver No 11 0.113 3 1 0.333 0
SASS6 SASS6 Q6UVJ0 Spindle assembly abnormal protein 6 homolog chr1 GO:0010638 Not Cancer Driver No 82 0.125 331 37 0.112 1
SAXO1 SAXO1 Q8IYX7 Stabilizer of axonemal microtubules 1 chr9 GO:0010638 Not Cancer Driver No 63 0.133 249 35 0.141 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0010638 Not Cancer Driver No 100 0.14 170 35 0.206 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0010638 Not Cancer Driver No 31 0.1 259 30 0.116 0
SDC4 SDC4 P31431 Syndecan-4 chr20 GO:0010638 Census, Compendium Yes 34 0.172 110 25 0.227 0
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0010638 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0010638 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEPT7_ENST00000350320 SEPTIN7 Q16181 Septin-7 chr7 GO:0010638 Not Cancer Driver No 49 0.112 200 21 0.105 0
SEPT9 SEPTIN9 Q9UHD8 Septin-9 chr17 GO:0010638 Not Cancer Driver No 84 0.143 332 50 0.151 2
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0010638 Not Cancer Driver No 62 0.126 112 21 0.188 1
SETDB1 SETDB1 Q15047 Histone-lysine N-methyltransferase SETDB1 chr1 GO:0010638 Census, Compendium Yes 184 0.143 597 77 0.129 0
SETDB2 SETDB2 Q96T68 Histone-lysine N-methyltransferase SETDB2 chr13 GO:0010638 Not Cancer Driver No 70 0.097 253 26 0.103 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0010638 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0010638 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0010638 Not Cancer Driver No 41 0.112 82 10 0.122 0
SHCBP1L SHCBP1L Q9BZQ2 Testicular spindle-associated protein SHCBP1L chr1 GO:0010638 Not Cancer Driver No 95 0.145 150 14 0.093 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0010638 Compendium Yes 172 0.135 617 73 0.118 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0010638 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0010638 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLAIN1_ENST00000466548 SLAIN1 Q8ND83 SLAIN motif-containing protein 1 chr13 GO:0010638 Not Cancer Driver No 62 0.109 485 58 0.12 0
SLAIN2 SLAIN2 Q9P270 SLAIN motif-containing protein 2 chr4 GO:0010638 Not Cancer Driver No 62 0.107 562 60 0.107 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0010638 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0010638 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0010638 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0010638 Not Cancer Driver No 112 0.095 725 76 0.105 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0010638 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0010638 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0010638 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMC2 SMC2 O95347 Structural maintenance of chromosomes protein 2 chr9 GO:0010638 Not Cancer Driver No 145 0.121 573 88 0.154 0
SMC4_ENST00000344722 SMC4 Q9NTJ3 Structural maintenance of chromosomes protein 4 chr3 GO:0010638 Not Cancer Driver No 175 0.136 539 55 0.102 0
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0010638 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0010638 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0010638 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX18 SNX18 Q96RF0 Sorting nexin-18 chr5 GO:0010638 Not Cancer Driver No 54 0.086 236 7 0.03 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 GO:0010638 Not Cancer Driver No 36 0.082 98 4 0.041 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0010638 Not Cancer Driver No 31 0.069 101 5 0.05 0
SORBS3 SORBS3 O60504 Vinexin chr8 GO:0010638 Not Cancer Driver No 62 0.092 577 56 0.097 0
SPAG5 SPAG5 Q96R06 Sperm-associated antigen 5 chr17 GO:0010638 Not Cancer Driver No 136 0.114 636 83 0.131 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:0010638 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPIRE1 SPIRE1 Q08AE8 Protein spire homolog 1 chr18 GO:0010638 Not Cancer Driver No 78 0.103 414 48 0.116 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0010638 Census Yes 53 0.099 130 11 0.085 1
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0010638 Not Cancer Driver No 27 0.182 0 0 0.0 6
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0010638 Not Cancer Driver No 66 0.224 103 18 0.175 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 GO:0010638 Census, Compendium Yes 147 0.114 735 85 0.116 1
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0010638 Not Cancer Driver No 34 0.19 122 23 0.189 0
STRA8 STRA8 Q7Z7C7 Stimulated by retinoic acid gene 8 protein homolog chr7 GO:0010638 Not Cancer Driver No 45 0.136 105 15 0.143 0
STX18 STX18 Q9P2W9 Syntaxin-18 chr4 GO:0010638 Not Cancer Driver No 28 0.084 174 15 0.086 0
SURF4 SURF4 O15260 Surfeit locus protein 4 chr9 GO:0010638 Not Cancer Driver No 29 0.108 0 0 0.0 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0010638 Not Cancer Driver No 44 0.075 271 18 0.066 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0010638 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNPO SYNPO Q8N3V7 Synaptopodin chr5 GO:0010638 Not Cancer Driver No 103 0.111 918 102 0.111 0
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0010638 Not Cancer Driver No 103 0.105 950 99 0.104 0
SYNPO2_ENST00000429713 SYNPO2 Q9UMS6 Synaptopodin-2 chr4 GO:0010638 Not Cancer Driver No 240 0.22 978 219 0.224 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0010638 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT9 SYT9 Q86SS6 Synaptotagmin-9 chr11 GO:0010638 Not Cancer Driver No 120 0.244 148 42 0.284 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0010638 Not Cancer Driver No 69 0.17 28 2 0.071 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0010638 Census Yes 54 0.163 305 53 0.174 0
TAPT1 TAPT1 Q6NXT6 Transmembrane anterior posterior transformation protein 1 homolog chr4 GO:0010638 Not Cancer Driver No 47 0.083 131 12 0.092 1
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0010638 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0010638 Not Cancer Driver No 219 0.195 126 22 0.175 10
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0010638 Not Cancer Driver No 33 0.061 361 20 0.055 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0010638 Not Cancer Driver No 63 0.101 339 35 0.103 0
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0010638 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0010638 Not Cancer Driver No 86 0.171 23 3 0.13 15
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 GO:0010638 Not Cancer Driver No 16 0.068 22 2 0.091 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0010638 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFSF10 TNFSF10 P50591 Tumor necrosis factor ligand superfamily member 10 chr3 GO:0010638 Not Cancer Driver No 43 0.153 61 7 0.115 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0010638 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0010638 Not Cancer Driver No 117 0.1 255 24 0.094 0
TOGARAM1_ENST00000361577 TOGARAM1 Q9Y4F4 TOG array regulator of axonemal microtubules protein 1 chr14 GO:0010638 Not Cancer Driver No 230 0.134 703 101 0.144 3
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0010638 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPM1_ENST00000403994 TPM1 P09493 Tropomyosin alpha-1 chain chr15 GO:0010638 Not Cancer Driver No 33 0.116 234 29 0.124 8
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0010638 Census Yes 311 0.132 1990 266 0.134 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0010638 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRIM27 TRIM27 P14373 Zinc finger protein RFP chr6 GO:0010638 Census Yes 59 0.115 87 11 0.126 0
TRIM28 TRIM28 Q13263 Transcription intermediary factor 1-beta chr19 GO:0010638 Not Cancer Driver No 87 0.104 430 41 0.095 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0010638 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSC1 TSC1 Q92574 Hamartin chr9 GO:0010638 Census, Compendium Yes 135 0.116 732 78 0.107 11
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0010638 Not Cancer Driver No 13 0.086 68 6 0.088 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0010638 Not Cancer Driver No 142 0.135 588 77 0.131 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0010638 Not Cancer Driver No 89 0.127 243 28 0.115 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0010638 Not Cancer Driver No 38 0.134 36 4 0.111 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0010638 Not Cancer Driver No 124 0.15 222 38 0.171 0
VPS13D VPS13D Q5THJ4 Intermembrane lipid transfer protein VPS13D chr1 GO:0010638 Not Cancer Driver No 501 0.114 973 118 0.121 8
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0010638 Not Cancer Driver No 68 0.085 99 9 0.091 1
VPS4B VPS4B O75351 Vacuolar protein sorting-associated protein 4B chr18 GO:0010638 Not Cancer Driver No 52 0.117 195 22 0.113 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0010638 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0010638 Not Cancer Driver No 63 0.113 445 49 0.11 0
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0010638 Not Cancer Driver No 61 0.122 400 43 0.107 0
WASF3 WASF3 Q9UPY6 Wiskott-Aldrich syndrome protein family member 3 chr13 GO:0010638 Not Cancer Driver No 108 0.215 386 84 0.218 0
WASHC2C_ENST00000374362 WASHC2C Q9Y4E1 WASH complex subunit 2C chr10 GO:0010638 Not Cancer Driver No 90 0.068 1204 89 0.074 0
WASL WASL O00401 Neural Wiskott-Aldrich syndrome protein chr7 GO:0010638 Not Cancer Driver No 72 0.143 394 57 0.145 0
WDR1 WDR1 O75083 WD repeat-containing protein 1 chr4 GO:0010638 Not Cancer Driver No 66 0.109 30 7 0.233 2
WDR45_ENST00000634944 WDR45 Q9Y484 WD repeat domain phosphoinositide-interacting protein 4 chrX GO:0010638 Compendium Yes 62 0.172 10 1 0.1 0
WHAMM WHAMM Q8TF30 WASP homolog-associated protein with actin, membranes and microtubules chr15 GO:0010638 Not Cancer Driver No 59 0.073 399 38 0.095 0
WIPI1 WIPI1 Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 chr17 GO:0010638 Not Cancer Driver No 45 0.101 113 9 0.08 0
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0010638 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0010638 Not Cancer Driver No 30 0.085 39 4 0.103 4
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0010638 Not Cancer Driver No 66 0.174 0 0 0.0 2
WRAP73 WRAP73 Q9P2S5 WD repeat-containing protein WRAP73 chr1 GO:0010638 Not Cancer Driver No 50 0.109 5 0 0.0 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0010638 Not Cancer Driver No 87 0.119 118 11 0.093 0
ZDHHC6 ZDHHC6 Q9H6R6 Palmitoyltransferase ZDHHC6 chr10 GO:0010638 Not Cancer Driver No 43 0.104 11 3 0.273 0
ZMYND10 ZMYND10 O75800 Zinc finger MYND domain-containing protein 10 chr3 GO:0010638 Not Cancer Driver No 40 0.091 38 6 0.158 5
ZNF205_ENST00000382192 ZNF205 O95201 Zinc finger protein 205 chr16 GO:0010638 Not Cancer Driver No 74 0.134 367 49 0.134 0
ZNF304_ENST00000391705 ZNF304 Q9HCX3 Zinc finger protein 304 chr19 GO:0010638 Not Cancer Driver No 126 0.191 54 12 0.222 0