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Total number of protein in "GO:0009896" GO term:  240

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AADAC AADAC P22760 Arylacetamide deacetylase chr3 GO:0009896 Not Cancer Driver No 80 0.201 4 0 0.0 0
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0009896 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0009896 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0009896 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0009896 Not Cancer Driver No 34 0.097 18 1 0.056 4
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0009896 Not Cancer Driver No 123 0.137 135 13 0.096 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0009896 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0009896 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0009896 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0009896 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0009896 Not Cancer Driver No 52 0.126 35 4 0.114 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0009896 Not Cancer Driver No 126 0.147 141 15 0.106 11
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0009896 Census Yes 77 0.16 84 9 0.107 2
AMBRA1_ENST00000458649 AMBRA1 Q9C0C7 Activating molecule in BECN1-regulated autophagy protein 1 chr11 GO:0009896 Not Cancer Driver No 173 0.133 788 103 0.131 0
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0009896 Not Cancer Driver No 52 0.113 154 26 0.169 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0009896 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0009896 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0009896 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0009896 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0009896 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0009896 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0009896 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0009896 Census Yes 77 0.098 511 56 0.11 0
ATG2A ATG2A Q2TAZ0 Autophagy-related protein 2 homolog A chr11 GO:0009896 Not Cancer Driver No 228 0.118 887 124 0.14 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009896 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0009896 Not Cancer Driver No 46 0.127 181 24 0.133 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0009896 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0009896 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0009896 Census Yes 30 0.156 39 2 0.051 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0009896 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0009896 Not Cancer Driver No 42 0.212 130 17 0.131 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0009896 Not Cancer Driver No 45 0.1 190 19 0.1 0
BNIP3L BNIP3L O60238 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like chr8 GO:0009896 Not Cancer Driver No 16 0.073 175 14 0.08 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0009896 Census Yes 32 0.203 7 2 0.286 0
C9orf72 C9orf72 Q96LT7 Guanine nucleotide exchange factor C9orf72 chr9 GO:0009896 Not Cancer Driver No 64 0.133 11 0 0.0 0
CALCOCO2_ENST00000258947 CALCOCO2 Q13137 Calcium-binding and coiled-coil domain-containing protein 2 chr17 GO:0009896 Not Cancer Driver No 42 0.094 212 19 0.09 0
CAMKK2 CAMKK2 Q96RR4 Calcium/calmodulin-dependent protein kinase kinase 2 chr12 GO:0009896 Not Cancer Driver No 65 0.111 281 35 0.125 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0009896 Not Cancer Driver No 30 0.169 2 0 0.0 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0009896 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDC20 CDC20 Q12834 Cell division cycle protein 20 homolog chr1 GO:0009896 Not Cancer Driver No 44 0.088 198 15 0.076 0
CDC20B CDC20B Q86Y33 Cell division cycle protein 20 homolog B chr5 GO:0009896 Not Cancer Driver No 99 0.191 152 24 0.158 0
CELF1_ENST00000358597 CELF1 Q92879 CUGBP Elav-like family member 1 chr11 GO:0009896 Not Cancer Driver No 56 0.115 166 17 0.102 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0009896 Not Cancer Driver No 29 0.083 19 0 0.0 1
CNOT1 CNOT1 A5YKK6 CCR4-NOT transcription complex subunit 1 chr16 GO:0009896 Not Cancer Driver No 346 0.146 464 56 0.121 12
CNOT7 CNOT7 Q9UIV1 CCR4-NOT transcription complex subunit 7 chr8 GO:0009896 Not Cancer Driver No 31 0.109 21 1 0.048 0
CNOT8 CNOT8 Q9UFF9 CCR4-NOT transcription complex subunit 8 chr5 GO:0009896 Not Cancer Driver No 30 0.103 6 0 0.0 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0009896 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0009896 Not Cancer Driver No 144 0.186 62 10 0.161 15
DAGLB DAGLB Q8NCG7 Diacylglycerol lipase-beta chr7 GO:0009896 Not Cancer Driver No 69 0.103 37 3 0.081 0
DCN DCN P07585 Decorin chr12 GO:0009896 Not Cancer Driver No 96 0.267 81 26 0.321 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0009896 Not Cancer Driver No 159 0.158 222 39 0.176 0
DIS3L2 DIS3L2 Q8IYB7 DIS3-like exonuclease 2 chr2 GO:0009896 Not Cancer Driver No 114 0.129 264 22 0.083 1
DND1 DND1 Q8IYX4 Dead end protein homolog 1 chr5 GO:0009896 Not Cancer Driver No 23 0.065 36 0 0.0 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0009896 Not Cancer Driver No 86 0.116 260 24 0.092 0
DXO_ENST00000375356 DXO O77932 Decapping and exoribonuclease protein chr6 GO:0009896 Not Cancer Driver No 46 0.116 143 17 0.119 0
EIF4ENIF1 EIF4ENIF1 Q9NRA8 Eukaryotic translation initiation factor 4E transporter chr22 GO:0009896 Not Cancer Driver No 116 0.118 899 101 0.112 0
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0009896 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0009896 Not Cancer Driver No 102 0.223 65 19 0.292 0
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0009896 Not Cancer Driver No 41 0.096 6 1 0.167 0
EXOSC7 EXOSC7 Q15024 Exosome complex component RRP42 chr3 GO:0009896 Not Cancer Driver No 41 0.141 8 1 0.125 0
EXOSC8 EXOSC8 Q96B26 Exosome complex component RRP43 chr13 GO:0009896 Not Cancer Driver No 20 0.072 28 1 0.036 2
EXOSC9_ENST00000243498 EXOSC9 Q06265 Exosome complex component RRP45 chr4 GO:0009896 Not Cancer Driver No 58 0.132 154 18 0.117 1
FABP1 FABP1 P07148 Fatty acid-binding protein, liver chr2 GO:0009896 Not Cancer Driver No 34 0.268 0 0 0.0 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0009896 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0009896 Not Cancer Driver No 68 0.114 120 4 0.033 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0009896 Not Cancer Driver No 37 0.177 109 24 0.22 0
FTO FTO Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO chr16 GO:0009896 Not Cancer Driver No 67 0.133 53 10 0.189 3
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0009896 Not Cancer Driver No 93 0.117 283 35 0.124 0
FYCO1 FYCO1 Q9BQS8 FYVE and coiled-coil domain-containing protein 1 chr3 GO:0009896 Not Cancer Driver No 181 0.122 892 106 0.119 1
FZR1 FZR1 Q9UM11 Fizzy-related protein homolog chr19 GO:0009896 Not Cancer Driver No 74 0.149 184 30 0.163 0
GAPDHS GAPDHS O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific chr19 GO:0009896 Not Cancer Driver No 71 0.174 111 19 0.171 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0009896 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0009896 Not Cancer Driver No 42 0.119 11 0 0.0 1
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0009896 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0009896 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPSM1 GPSM1 Q86YR5 G-protein-signaling modulator 1 chr9 GO:0009896 Not Cancer Driver No 68 0.101 344 35 0.102 0
GRSF1 GRSF1 Q12849 G-rich sequence factor 1 chr4 GO:0009896 Not Cancer Driver No 49 0.102 147 20 0.136 0
GTPBP1 GTPBP1 O00178 GTP-binding protein 1 chr22 GO:0009896 Not Cancer Driver No 75 0.112 263 26 0.099 0
HERPUD1 HERPUD1 Q15011 Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein chr16 GO:0009896 Census Yes 38 0.097 248 17 0.069 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0009896 Census Yes 118 0.143 435 51 0.117 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0009896 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0009896 Not Cancer Driver No 39 0.11 206 19 0.092 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009896 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPB8 HSPB8 Q9UJY1 Heat shock protein beta-8 chr12 GO:0009896 Not Cancer Driver No 40 0.204 130 31 0.238 5
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0009896 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTT HTT P42858 Huntingtin chr4 GO:0009896 Not Cancer Driver No 336 0.107 666 69 0.104 2
IFNG IFNG P01579 Interferon gamma chr12 GO:0009896 Not Cancer Driver No 51 0.307 23 6 0.261 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0009896 Not Cancer Driver No 45 0.231 87 23 0.264 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0009896 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0009896 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0009896 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0009896 Not Cancer Driver No 35 0.165 58 7 0.121 0
INS INS P01308 Insulin chr11 GO:0009896 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0009896 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0009896 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0009896 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0009896 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0009896 Not Cancer Driver No 95 0.105 335 42 0.125 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0009896 Census, Compendium Yes 357 0.263 275 55 0.2 2
KHSRP KHSRP Q92945 Far upstream element-binding protein 2 chr19 GO:0009896 Not Cancer Driver No 84 0.118 684 81 0.118 0
KIAA1324 ELAPOR1 Q6UXG2 Endosome/lysosome-associated apoptosis and autophagy regulator 1 chr1 GO:0009896 Not Cancer Driver No 94 0.093 56 5 0.089 0
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0009896 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0009896 Not Cancer Driver No 46 0.176 16 6 0.375 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0009896 Not Cancer Driver No 119 0.138 63 3 0.048 104
LIN28B LIN28B Q6ZN17 Protein lin-28 homolog B chr6 GO:0009896 Not Cancer Driver No 60 0.24 179 32 0.179 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0009896 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0009896 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRSAM1_ENST00000373322 LRSAM1 Q6UWE0 E3 ubiquitin-protein ligase LRSAM1 chr9 GO:0009896 Not Cancer Driver No 86 0.119 240 30 0.125 1
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0009896 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0009896 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0009896 Not Cancer Driver No 59 0.139 90 8 0.089 0
MARCH2 MARCHF2 Q9P0N8 E3 ubiquitin-protein ligase MARCHF2 chr19 GO:0009896 Not Cancer Driver No 33 0.134 23 5 0.217 0
METTL14 METTL14 Q9HCE5 N6-adenosine-methyltransferase non-catalytic subunit chr4 GO:0009896 Not Cancer Driver No 60 0.132 224 26 0.116 0
METTL16 METTL16 Q86W50 RNA N6-adenosine-methyltransferase METTL16 chr17 GO:0009896 Not Cancer Driver No 55 0.098 172 22 0.128 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0009896 Not Cancer Driver No 74 0.128 274 29 0.106 0
MEX3D MEX3D Q86XN8 RNA-binding protein MEX3D chr19 GO:0009896 Not Cancer Driver No 35 0.054 501 24 0.048 0
MKRN2 MKRN2 Q9H000 E3 ubiquitin-protein ligase makorin-2 chr3 GO:0009896 Not Cancer Driver No 45 0.108 145 16 0.11 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0009896 Not Cancer Driver No 106 0.124 554 66 0.119 0
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0009896 Not Cancer Driver No 48 0.137 47 8 0.17 0
MOV10_ENST00000357443 MOV10 Q9HCE1 Helicase MOV-10 chr1 GO:0009896 Not Cancer Driver No 110 0.11 101 8 0.079 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009896 Census, Compendium Yes 80 0.182 299 46 0.154 0
NANOS1 NANOS1 Q8WY41 Nanos homolog 1 chr10 GO:0009896 Not Cancer Driver No 7 0.024 169 2 0.012 0
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0009896 Not Cancer Driver No 29 0.21 50 11 0.22 0
NANOS3_ENST00000397555 NANOS3 P60323 Nanos homolog 3 chr19 GO:0009896 Not Cancer Driver No 31 0.179 117 25 0.214 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009896 Census, Compendium Yes 228 0.377 402 62 0.154 4
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0009896 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0009896 Not Cancer Driver No 169 0.163 40 4 0.1 15
NRDC_ENST00000352171 NRDC O43847 Nardilysin chr1 GO:0009896 Not Cancer Driver No 162 0.141 253 34 0.134 0
OPTN_ENST00000263036 OPTN Q96CV9 Optineurin chr10 GO:0009896 Not Cancer Driver No 58 0.101 470 51 0.109 6
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0009896 Not Cancer Driver No 51 0.086 14 2 0.143 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0009896 Census, Compendium Yes 100 0.157 317 55 0.174 0
PACSIN3_ENST00000298838 PACSIN3 Q9UKS6 Protein kinase C and casein kinase substrate in neurons protein 3 chr11 GO:0009896 Not Cancer Driver No 52 0.123 290 31 0.107 0
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0009896 Census Yes 25 0.109 43 1 0.023 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0009896 Not Cancer Driver No 11 0.058 30 0 0.0 5
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0009896 Not Cancer Driver No 86 0.124 148 27 0.182 9
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:0009896 Not Cancer Driver No 48 0.118 50 6 0.12 4
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0009896 Not Cancer Driver No 57 0.098 99 13 0.131 23
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0009896 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0009896 Not Cancer Driver No 62 0.147 111 23 0.207 0
PLEKHN1 PLEKHN1 Q494U1 Pleckstrin homology domain-containing family N member 1 chr1 GO:0009896 Not Cancer Driver No 59 0.097 369 37 0.1 0
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0009896 Not Cancer Driver No 49 0.106 192 21 0.109 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0009896 Not Cancer Driver No 75 0.116 202 15 0.074 0
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0009896 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0009896 Not Cancer Driver No 86 0.11 115 10 0.087 2
POLR2G POLR2G P62487 DNA-directed RNA polymerase II subunit RPB7 chr11 GO:0009896 Not Cancer Driver No 15 0.087 15 1 0.067 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0009896 Not Cancer Driver No 63 0.135 68 9 0.132 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009896 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0009896 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009896 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0009896 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0009896 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0009896 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRXL2C PRXL2C Q7RTV5 Peroxiredoxin-like 2C chr9 GO:0009896 Not Cancer Driver No 10 0.044 26 0 0.0 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0009896 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0009896 Not Cancer Driver No 49 0.113 140 25 0.179 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0009896 Not Cancer Driver No 150 0.126 640 77 0.12 3
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0009896 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0009896 Not Cancer Driver No 168 0.121 143 17 0.119 2
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0009896 Not Cancer Driver No 36 0.175 35 5 0.143 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0009896 Not Cancer Driver No 29 0.123 20 3 0.15 0
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0009896 Not Cancer Driver No 158 0.139 796 115 0.144 0
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0009896 Not Cancer Driver No 63 0.14 105 13 0.124 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0009896 Not Cancer Driver No 20 0.146 3 0 0.0 0
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0009896 Not Cancer Driver No 63 0.117 143 20 0.14 0
RNF128 RNF128 Q8TEB7 E3 ubiquitin-protein ligase RNF128 chrX GO:0009896 Not Cancer Driver No 61 0.143 123 15 0.122 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0009896 Not Cancer Driver No 25 0.13 82 15 0.183 0
RNF31 RNF31 Q96EP0 E3 ubiquitin-protein ligase RNF31 chr14 GO:0009896 Not Cancer Driver No 142 0.132 319 45 0.141 0
RNFT1 RNFT1 Q5M7Z0 E3 ubiquitin-protein ligase RNFT1 chr17 GO:0009896 Not Cancer Driver No 37 0.085 117 18 0.154 0
RNFT2_ENST00000392549 RNFT2 Q96EX2 RING finger and transmembrane domain-containing protein 2 chr12 GO:0009896 Not Cancer Driver No 37 0.083 129 10 0.078 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0009896 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0009896 Not Cancer Driver No 145 0.104 732 81 0.111 0
RUFY4_ENST00000344321 RUFY4 Q6ZNE9 RUN and FYVE domain-containing protein 4 chr2 GO:0009896 Not Cancer Driver No 77 0.135 307 51 0.166 0
SCOC SCOC Q9UIL1 Short coiled-coil protein chr4 GO:0009896 Not Cancer Driver No 13 0.082 82 8 0.098 0
SCT SCT P09683 Secretin chr11 GO:0009896 Not Cancer Driver No 4 0.033 71 3 0.042 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0009896 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0009896 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0009896 Not Cancer Driver No 84 0.171 44 4 0.091 0
SGTA SGTA O43765 Small glutamine-rich tetratricopeptide repeat-containing protein alpha chr19 GO:0009896 Not Cancer Driver No 38 0.121 159 23 0.145 0
SH3D19_ENST00000409252 SH3D19 Q5HYK7 SH3 domain-containing protein 19 chr4 GO:0009896 Not Cancer Driver No 86 0.109 526 52 0.099 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0009896 Not Cancer Driver No 41 0.112 82 10 0.122 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009896 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0009896 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIRT6 SIRT6 Q8N6T7 NAD-dependent protein deacylase sirtuin-6 chr19 GO:0009896 Not Cancer Driver No 33 0.093 164 12 0.073 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0009896 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0009896 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC4A4_ENST00000264485 SLC4A4 Q9Y6R1 Electrogenic sodium bicarbonate cotransporter 1 chr4 GO:0009896 Not Cancer Driver No 193 0.179 281 60 0.214 8
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0009896 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0009896 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX18 SNX18 Q96RF0 Sorting nexin-18 chr5 GO:0009896 Not Cancer Driver No 54 0.086 236 7 0.03 0
SNX30 SNX30 Q5VWJ9 Sorting nexin-30 chr9 GO:0009896 Not Cancer Driver No 36 0.082 98 4 0.041 0
SNX33 SNX33 Q8WV41 Sorting nexin-33 chr15 GO:0009896 Not Cancer Driver No 63 0.11 204 18 0.088 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0009896 Not Cancer Driver No 31 0.069 101 5 0.05 0
SNX9 SNX9 Q9Y5X1 Sorting nexin-9 chr6 GO:0009896 Not Cancer Driver No 71 0.119 231 23 0.1 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0009896 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:0009896 Not Cancer Driver No 72 0.128 9 2 0.222 5
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0009896 Not Cancer Driver No 17 0.215 0 0 0.0 0
SUPT5H SUPT5H O00267 Transcription elongation factor SPT5 chr19 GO:0009896 Not Cancer Driver No 165 0.152 572 87 0.152 0
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0009896 Not Cancer Driver No 72 0.092 140 12 0.086 0
TARDBP TARDBP Q13148 TAR DNA-binding protein 43 chr1 GO:0009896 Not Cancer Driver No 51 0.123 202 15 0.074 27
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0009896 Not Cancer Driver No 101 0.139 42 5 0.119 12
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0009896 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM259 TMEM259 Q4ZIN3 Membralin chr19 GO:0009896 Not Cancer Driver No 40 0.065 188 9 0.048 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009896 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0009896 Not Cancer Driver No 48 0.104 229 28 0.122 0
TNRC6A TNRC6A Q8NDV7 Trinucleotide repeat-containing gene 6A protein chr16 GO:0009896 Not Cancer Driver No 284 0.145 1830 265 0.145 0
TNRC6B TNRC6B Q9UPQ9 Trinucleotide repeat-containing gene 6B protein chr22 GO:0009896 Not Cancer Driver No 205 0.112 1735 195 0.112 0
TNRC6C_ENST00000301624 TNRC6C Q9HCJ0 Trinucleotide repeat-containing gene 6C protein chr17 GO:0009896 Not Cancer Driver No 170 0.101 1564 162 0.104 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0009896 Not Cancer Driver No 35 0.101 214 18 0.084 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0009896 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRIM71 TRIM71 Q2Q1W2 E3 ubiquitin-protein ligase TRIM71 chr3 GO:0009896 Not Cancer Driver No 124 0.143 163 21 0.129 2
TSC1 TSC1 Q92574 Hamartin chr9 GO:0009896 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSC2 TSC2 P49815 Tuberin chr16 GO:0009896 Census, Compendium Yes 192 0.106 563 50 0.089 53
TTC5 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0009896 Not Cancer Driver No 65 0.148 151 19 0.126 0
TUT4_ENST00000371544 TUT4 Q5TAX3 Terminal uridylyltransferase 4 chr1 GO:0009896 Not Cancer Driver No 187 0.114 771 102 0.132 0
TUT7 TUT7 Q5VYS8 Terminal uridylyltransferase 7 chr9 GO:0009896 Not Cancer Driver No 159 0.106 659 74 0.112 0
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0009896 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBQLN1 UBQLN1 Q9UMX0 Ubiquilin-1 chr9 GO:0009896 Not Cancer Driver No 64 0.109 543 58 0.107 0
UBQLN2 UBQLN2 Q9UHD9 Ubiquilin-2 chrX GO:0009896 Not Cancer Driver No 82 0.131 581 79 0.136 8
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0009896 Not Cancer Driver No 142 0.135 588 77 0.131 0
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0009896 Not Cancer Driver No 146 0.129 329 36 0.109 0
USP13 USP13 Q92995 Ubiquitin carboxyl-terminal hydrolase 13 chr3 GO:0009896 Not Cancer Driver No 121 0.14 224 42 0.188 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0009896 Not Cancer Driver No 89 0.127 243 28 0.115 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0009896 Not Cancer Driver No 38 0.134 36 4 0.111 0
VPS13D VPS13D Q5THJ4 Intermembrane lipid transfer protein VPS13D chr1 GO:0009896 Not Cancer Driver No 501 0.114 973 118 0.121 8
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0009896 Not Cancer Driver No 52 0.167 135 19 0.141 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0009896 Not Cancer Driver No 106 0.164 571 95 0.166 0
WDR45_ENST00000634944 WDR45 Q9Y484 WD repeat domain phosphoinositide-interacting protein 4 chrX GO:0009896 Compendium Yes 62 0.172 10 1 0.1 0
WIPI1 WIPI1 Q5MNZ9 WD repeat domain phosphoinositide-interacting protein 1 chr17 GO:0009896 Not Cancer Driver No 45 0.101 113 9 0.08 0
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0009896 Not Cancer Driver No 87 0.156 369 46 0.125 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0009896 Not Cancer Driver No 67 0.116 376 44 0.117 0
YTHDF3_ENST00000539294 YTHDF3 Q7Z739 YTH domain-containing family protein 3 chr8 GO:0009896 Not Cancer Driver No 74 0.126 409 51 0.125 0
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0009896 Compendium Yes 151 0.204 433 80 0.185 4
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0009896 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H12D ZC3H12D A2A288 Probable ribonuclease ZC3H12D chr6 GO:0009896 Not Cancer Driver No 48 0.091 314 18 0.057 0
ZC3H18_ENST00000301011 ZC3H18 Q86VM9 Zinc finger CCCH domain-containing protein 18 chr16 GO:0009896 Not Cancer Driver No 139 0.146 929 134 0.144 0
ZC3HAV1 ZC3HAV1 Q7Z2W4 Zinc finger CCCH-type antiviral protein 1 chr7 GO:0009896 Not Cancer Driver No 142 0.157 344 63 0.183 0
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0009896 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0009896 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0009896 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZSWIM8_ENST00000605216 ZSWIM8 A7E2V4 Zinc finger SWIM domain-containing protein 8 chr10 GO:0009896 Not Cancer Driver No 204 0.111 877 103 0.117 0