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Total number of protein in "GO:0009891" GO term:  528

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0009891 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCB10 ABCB10 Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial chr1 GO:0009891 Not Cancer Driver No 103 0.14 47 0 0.0 0
ABCB7_ENST00000373394 ABCB7 O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial chrX GO:0009891 Not Cancer Driver No 117 0.156 79 14 0.177 4
ABCD1 ABCD1 P33897 ATP-binding cassette sub-family D member 1 chrX GO:0009891 Not Cancer Driver No 106 0.142 75 5 0.067 138
ABCD2 ABCD2 Q9UBJ2 ATP-binding cassette sub-family D member 2 chr12 GO:0009891 Not Cancer Driver No 150 0.203 29 4 0.138 0
ABCG1 ABCG1 P45844 ATP-binding cassette sub-family G member 1 chr21 GO:0009891 Not Cancer Driver No 104 0.153 32 5 0.156 0
ABCG4 ABCG4 Q9H172 ATP-binding cassette sub-family G member 4 chr11 GO:0009891 Not Cancer Driver No 122 0.189 29 7 0.241 0
ABHD6 ABHD6 Q9BV23 Monoacylglycerol lipase ABHD6 chr3 GO:0009891 Not Cancer Driver No 38 0.113 11 2 0.182 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0009891 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACSL3 ACSL3 O95573 Fatty acid CoA ligase Acsl3 chr2 GO:0009891 Census, Compendium Yes 89 0.124 47 7 0.149 0
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0009891 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0009891 Compendium Yes 213 0.134 485 47 0.097 0
ADGRF5_ENST00000265417 ADGRF5 Q8IZF2 Adhesion G protein-coupled receptor F5 chr6 GO:0009891 Not Cancer Driver No 255 0.189 53 11 0.208 0
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0009891 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0009891 Not Cancer Driver No 23 0.069 0 0 0.0 0
AGO2 AGO2 Q9UKV8 Protein argonaute-2 chr8 GO:0009891 Not Cancer Driver No 126 0.147 141 15 0.106 11
AGT AGT P01019 Angiotensinogen chr1 GO:0009891 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0009891 Not Cancer Driver No 98 0.27 0 0 0.0 0
AGXT2 AGXT2 Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial chr5 GO:0009891 Not Cancer Driver No 136 0.265 11 5 0.455 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0009891 Not Cancer Driver No 14 0.095 61 6 0.098 0
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0009891 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0009891 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0009891 Census Yes 77 0.16 84 9 0.107 2
ALG10B ALG10B Q5I7T1 Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase chr12 GO:0009891 Not Cancer Driver No 90 0.19 0 0 0.0 0
AMELX_ENST00000380714 AMELX Q99217 Amelogenin, X isoform chrX GO:0009891 Not Cancer Driver No 40 0.209 127 28 0.22 3
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0009891 Not Cancer Driver No 59 0.171 61 12 0.197 0
APLN APLN Q9ULZ1 Apelin chrX GO:0009891 Not Cancer Driver No 8 0.104 51 6 0.118 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0009891 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA4 APOA4 P06727 Apolipoprotein A-IV chr11 GO:0009891 Not Cancer Driver No 77 0.194 298 65 0.218 0
APOA5 APOA5 Q6Q788 Apolipoprotein A-V chr11 GO:0009891 Not Cancer Driver No 51 0.139 178 26 0.146 0
APOC2 APOC2 P02655 Apolipoprotein C-II chr19 GO:0009891 Not Cancer Driver No 8 0.079 14 2 0.143 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0009891 Not Cancer Driver No 25 0.079 124 6 0.048 12
APPL1 APPL1 Q9UKG1 DCC-interacting protein 13-alpha chr3 GO:0009891 Not Cancer Driver No 67 0.094 292 31 0.106 1
AR AR P10275 Androgen receptor chrX GO:0009891 Census, Compendium Yes 196 0.213 443 88 0.199 169
ARFGEF1 ARFGEF1 Q9Y6D6 Brefeldin A-inhibited guanine nucleotide-exchange protein 1 chr8 GO:0009891 Not Cancer Driver No 243 0.131 456 54 0.118 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0009891 Census Yes 77 0.098 511 56 0.11 0
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0009891 Not Cancer Driver No 17 0.152 112 17 0.152 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0009891 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASIP_ENST00000374954 ASIP P42127 Agouti-signaling protein chr20 GO:0009891 Not Cancer Driver No 16 0.121 36 9 0.25 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0009891 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0009891 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0009891 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0009891 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0009891 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATF6B ATF6B Q99941 Cyclic AMP-dependent transcription factor ATF-6 beta chr6 GO:0009891 Not Cancer Driver No 70 0.1 557 59 0.106 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009891 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH8 ATOH8 Q96SQ7 Transcription factor ATOH8 chr2 GO:0009891 Not Cancer Driver No 31 0.097 254 23 0.091 0
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0009891 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0009891 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0009891 Census, Compendium Yes 487 0.195 1672 301 0.18 33
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0009891 Not Cancer Driver No 51 0.148 63 8 0.127 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0009891 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0009891 Not Cancer Driver No 105 0.251 68 25 0.368 0
AVPR1B AVPR1B P47901 Vasopressin V1b receptor chr1 GO:0009891 Not Cancer Driver No 83 0.196 51 5 0.098 0
AZU1 AZU1 P20160 Azurocidin chr19 GO:0009891 Not Cancer Driver No 42 0.167 53 13 0.245 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0009891 Not Cancer Driver No 153 0.103 840 87 0.104 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0009891 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0009891 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0009891 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0009891 Census, Compendium Yes 66 0.124 21 0 0.0 8
BNC1 BNC1 Q01954 Zinc finger protein basonuclin-1 chr15 GO:0009891 Not Cancer Driver No 195 0.196 530 111 0.209 0
BRDT_ENST00000362005 BRDT Q58F21 Bromodomain testis-specific protein chr1 GO:0009891 Not Cancer Driver No 173 0.183 703 121 0.172 0
BRF1 BRF1 Q92994 Transcription factor IIIB 90 kDa subunit chr14 GO:0009891 Not Cancer Driver No 90 0.133 399 45 0.113 4
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0009891 Not Cancer Driver No 14 0.05 103 6 0.058 2
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0009891 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARF CARF Q8N187 Calcium-responsive transcription factor chr2 GO:0009891 Not Cancer Driver No 93 0.128 503 63 0.125 0
CCDC3 CCDC3 Q9BQI4 Coiled-coil domain-containing protein 3 chr10 GO:0009891 Not Cancer Driver No 40 0.148 68 18 0.265 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0009891 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0009891 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0009891 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0009891 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0009891 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0009891 Census, Compendium Yes 50 0.132 0 0 0.0 0
CCT2 CCT2 P78371 T-complex protein 1 subunit beta chr12 GO:0009891 Not Cancer Driver No 63 0.118 46 3 0.065 0
CCT3 CCT3 P49368 T-complex protein 1 subunit gamma chr1 GO:0009891 Not Cancer Driver No 71 0.13 95 12 0.126 0
CCT4 CCT4 P50991 T-complex protein 1 subunit delta chr2 GO:0009891 Not Cancer Driver No 51 0.095 92 2 0.022 0
CCT5 CCT5 P48643 T-complex protein 1 subunit epsilon chr5 GO:0009891 Not Cancer Driver No 83 0.153 72 10 0.139 1
CCT6A CCT6A P40227 T-complex protein 1 subunit zeta chr7 GO:0009891 Not Cancer Driver No 66 0.124 5 1 0.2 0
CCT7 CCT7 Q99832 T-complex protein 1 subunit eta chr2 GO:0009891 Not Cancer Driver No 59 0.109 36 6 0.167 0
CCT8 CCT8 P50990 T-complex protein 1 subunit theta chr21 GO:0009891 Not Cancer Driver No 41 0.075 36 2 0.056 0
CD244 CD244 Q9BZW8 Natural killer cell receptor 2B4 chr1 GO:0009891 Not Cancer Driver No 77 0.208 92 22 0.239 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0009891 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0009891 Census Yes 31 0.105 185 20 0.108 0
CDC7 CDC7 O00311 Cell division cycle 7-related protein kinase chr1 GO:0009891 Not Cancer Driver No 72 0.125 185 24 0.13 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0009891 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0009891 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0009891 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDT1 CDT1 Q9H211 DNA replication factor Cdt1 chr16 GO:0009891 Not Cancer Driver No 60 0.11 377 35 0.093 5
CEBPA CEBPA P49715 CCAAT/enhancer-binding protein alpha chr19 GO:0009891 Census, Compendium Yes 12 0.034 342 12 0.035 1
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0009891 Not Cancer Driver No 3 0.009 276 2 0.007 0
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0009891 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHCHD10_ENST00000484558 CHCHD10 Q8WYQ3 Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial chr22 GO:0009891 Not Cancer Driver No 8 0.056 97 4 0.041 4
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0009891 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0009891 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHP1 CHP1 Q99653 Calcineurin B homologous protein 1 chr15 GO:0009891 Not Cancer Driver No 27 0.138 70 12 0.171 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0009891 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0009891 Not Cancer Driver No 13 0.107 7 0 0.0 0
CIITA_ENST00000324288 CIITA P33076 MHC class II transactivator chr16 GO:0009891 Census, Compendium Yes 195 0.173 318 53 0.167 2
CIZ1_ENST00000634901 CIZ1 Q9ULV3 Cip1-interacting zinc finger protein chr9 GO:0009891 Not Cancer Driver No 93 0.104 708 83 0.117 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0009891 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0009891 Not Cancer Driver No 43 0.174 46 2 0.043 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0009891 Not Cancer Driver No 69 0.154 156 27 0.173 0
CNBP_ENST00000422453 CNBP P62633 CCHC-type zinc finger nucleic acid binding protein chr3 GO:0009891 Census Yes 11 0.062 19 0 0.0 0
CNEP1R1_ENST00000427478 CNEP1R1 Q8N9A8 Nuclear envelope phosphatase-regulatory subunit 1 chr16 GO:0009891 Not Cancer Driver No 8 0.064 0 0 0.0 0
COA3 COA3 Q9Y2R0 Cytochrome c oxidase assembly factor 3 homolog, mitochondrial chr17 GO:0009891 Not Cancer Driver No 4 0.038 57 3 0.053 0
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0009891 Census Yes 25 0.076 277 23 0.083 0
CREB3 CREB3 O43889 Cyclic AMP-responsive element-binding protein 3 chr9 GO:0009891 Not Cancer Driver No 33 0.089 168 11 0.065 0
CREB3L1 CREB3L1 Q96BA8 Cyclic AMP-responsive element-binding protein 3-like protein 1 chr11 GO:0009891 Census Yes 68 0.131 372 50 0.134 0
CREB3L3 CREB3L3 Q68CJ9 Cyclic AMP-responsive element-binding protein 3-like protein 3 chr19 GO:0009891 Not Cancer Driver No 96 0.208 338 67 0.198 1
CREBL2 CREBL2 O60519 cAMP-responsive element-binding protein-like 2 chr12 GO:0009891 Not Cancer Driver No 15 0.125 78 5 0.064 0
CSDE1_ENST00000358528 CSDE1 O75534 Cold shock domain-containing protein E1 chr1 GO:0009891 Not Cancer Driver No 118 0.148 204 29 0.142 0
CTDNEP1_ENST00000318988 CTDNEP1 O95476 CTD nuclear envelope phosphatase 1 chr17 GO:0009891 Not Cancer Driver No 20 0.082 0 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0009891 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009891 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0009891 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP7A1 CYP7A1 P22680 Cytochrome P450 7A1 chr8 GO:0009891 Not Cancer Driver No 109 0.216 48 8 0.167 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0009891 Not Cancer Driver No 144 0.187 680 125 0.184 0
DBF4 DBF4 Q9UBU7 Protein DBF4 homolog A chr7 GO:0009891 Not Cancer Driver No 75 0.111 333 26 0.078 0
DBF4B DBF4B Q8NFT6 Protein DBF4 homolog B chr17 GO:0009891 Not Cancer Driver No 68 0.111 311 22 0.071 0
DDAH1 DDAH1 O94760 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 chr1 GO:0009891 Not Cancer Driver No 28 0.098 44 3 0.068 0
DDAH2_ENST00000375787 DDAH2 O95865 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 chr6 GO:0009891 Not Cancer Driver No 24 0.084 96 6 0.062 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0009891 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0009891 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0009891 Not Cancer Driver No 154 0.159 280 55 0.196 1
DDX21 DDX21 Q9NR30 Nucleolar RNA helicase 2 chr10 GO:0009891 Not Cancer Driver No 72 0.092 342 30 0.088 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0009891 Census, Compendium Yes 133 0.201 301 47 0.156 18
DEK DEK P35659 Protein DEK chr6 GO:0009891 Census Yes 47 0.125 297 41 0.138 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0009891 Not Cancer Driver No 56 0.144 17 2 0.118 0
DHX33 DHX33 Q9H6R0 ATP-dependent RNA helicase DHX33 chr17 GO:0009891 Not Cancer Driver No 53 0.075 125 12 0.096 0
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0009891 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0009891 Compendium Yes 182 0.143 331 42 0.127 0
DKC1 DKC1 O60832 H/ACA ribonucleoprotein complex subunit DKC1 chrX GO:0009891 Not Cancer Driver No 62 0.121 145 29 0.2 24
DLX5 DLX5 P56178 Homeobox protein DLX-5 chr7 GO:0009891 Not Cancer Driver No 71 0.246 223 57 0.256 1
DNAJC3 DNAJC3 Q13217 DnaJ homolog subfamily C member 3 chr13 GO:0009891 Not Cancer Driver No 60 0.119 131 17 0.13 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0009891 Census Yes 138 0.159 270 43 0.159 22
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0009891 Not Cancer Driver No 28 0.071 41 4 0.098 0
DUOXA1_ENST00000560572 DUOXA1 Q1HG43 Dual oxidase maturation factor 1 chr15 GO:0009891 Not Cancer Driver No 40 0.117 38 7 0.184 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 GO:0009891 Not Cancer Driver No 40 0.125 0 0 0.0 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0009891 Not Cancer Driver No 77 0.128 294 39 0.133 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0009891 Not Cancer Driver No 122 0.134 554 70 0.126 0
E2F8_ENST00000250024 E2F8 A0AVK6 Transcription factor E2F8 chr11 GO:0009891 Not Cancer Driver No 132 0.152 582 85 0.146 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0009891 Not Cancer Driver No 37 0.175 97 20 0.206 3
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0009891 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0009891 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK3 EIF2AK3 Q9NZJ5 Eukaryotic translation initiation factor 2-alpha kinase 3 chr2 GO:0009891 Not Cancer Driver No 149 0.134 410 51 0.124 1
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0009891 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S3 EIF2S3 P41091 Eukaryotic translation initiation factor 2 subunit 3 chrX GO:0009891 Not Cancer Driver No 52 0.11 51 7 0.137 1
EIF2S3B EIF2S3B Q2VIR3 Eukaryotic translation initiation factor 2 subunit 3B chr12 GO:0009891 Not Cancer Driver No 16 0.034 53 2 0.038 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0009891 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF5A2 EIF5A2 Q9GZV4 Eukaryotic translation initiation factor 5A-2 chr3 GO:0009891 Not Cancer Driver No 20 0.131 28 4 0.143 0
EIF5AL1 EIF5AL1 Q6IS14 Eukaryotic translation initiation factor 5A-1-like chr10 GO:0009891 Not Cancer Driver No 21 0.136 16 4 0.25 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0009891 Not Cancer Driver No 37 0.24 21 5 0.238 5
ELL ELL P55199 RNA polymerase II elongation factor ELL chr19 GO:0009891 Census, Compendium Yes 67 0.108 446 53 0.119 0
ELOVL5_ENST00000304434 ELOVL5 Q9NYP7 Elongation of very long chain fatty acids protein 5 chr6 GO:0009891 Not Cancer Driver No 34 0.114 25 4 0.16 2
ENDOG ENDOG Q14249 Endonuclease G, mitochondrial chr9 GO:0009891 Not Cancer Driver No 11 0.037 61 1 0.016 0
ENG ENG P17813 Endoglin chr9 GO:0009891 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENO1 ENO1 P06733 Alpha-enolase chr1 GO:0009891 Not Cancer Driver No 51 0.118 21 2 0.095 0
ENPP7 ENPP7 Q6UWV6 Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 chr17 GO:0009891 Not Cancer Driver No 102 0.223 65 19 0.292 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009891 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0009891 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0009891 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0009891 Not Cancer Driver No 211 0.141 829 117 0.141 9
ESRRB_ENST00000512784 ESRRB O95718 Steroid hormone receptor ERR2 chr14 GO:0009891 Not Cancer Driver No 90 0.208 35 7 0.2 4
ETS1_ENST00000319397 ETS1 P14921 Protein C-ets-1 chr11 GO:0009891 Not Cancer Driver No 68 0.154 78 9 0.115 0
F2 F2 P00734 Prothrombin chr11 GO:0009891 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0009891 Not Cancer Driver No 73 0.172 19 2 0.105 0
FABP3 FABP3 P05413 Fatty acid-binding protein, heart chr1 GO:0009891 Not Cancer Driver No 22 0.165 3 0 0.0 0
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0009891 Not Cancer Driver No 74 0.104 30 2 0.067 0
FASTKD3 FASTKD3 Q14CZ7 FAST kinase domain-containing protein 3, mitochondrial chr5 GO:0009891 Not Cancer Driver No 106 0.16 6 1 0.167 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0009891 Not Cancer Driver No 55 0.142 68 7 0.103 0
FCER2 FCER2 P06734 Low affinity immunoglobulin epsilon Fc receptor chr19 GO:0009891 Not Cancer Driver No 41 0.128 130 22 0.169 0
FGF1_ENST00000612258 FGF1 P05230 Fibroblast growth factor 1 chr5 GO:0009891 Not Cancer Driver No 30 0.194 29 2 0.069 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0009891 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR4 FGFR4 P22455 Fibroblast growth factor receptor 4 chr5 GO:0009891 Census, Compendium Yes 113 0.141 162 28 0.173 0
FOS FOS P01100 Protein c-Fos chr14 GO:0009891 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0009891 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0009891 Compendium Yes 70 0.153 258 34 0.132 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0009891 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0009891 Census, Compendium Yes 70 0.104 595 68 0.114 0
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0009891 Not Cancer Driver No 31 0.24 0 0 0.0 1
GATA2_ENST00000487848 GATA2 P23769 Endothelial transcription factor GATA-2 chr3 GO:0009891 Census, Compendium Yes 72 0.15 370 49 0.132 6
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009891 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0009891 Not Cancer Driver No 40 0.101 268 24 0.09 9
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0009891 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCG GCG P01275 Pro-glucagon chr2 GO:0009891 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0009891 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCN1 GCN1 Q92616 eIF-2-alpha kinase activator GCN1 chr12 GO:0009891 Not Cancer Driver No 327 0.122 117 16 0.137 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0009891 Not Cancer Driver No 10 0.049 97 4 0.041 1
GINS1 GINS1 Q14691 DNA replication complex GINS protein PSF1 chr20 GO:0009891 Not Cancer Driver No 21 0.107 18 3 0.167 2
GINS2 GINS2 Q9Y248 DNA replication complex GINS protein PSF2 chr16 GO:0009891 Not Cancer Driver No 19 0.103 38 5 0.132 0
GINS3_ENST00000318129 GINS3 Q9BRX5 DNA replication complex GINS protein PSF3 chr16 GO:0009891 Not Cancer Driver No 36 0.167 14 0 0.0 0
GINS4 GINS4 Q9BRT9 DNA replication complex GINS protein SLD5 chr8 GO:0009891 Not Cancer Driver No 32 0.143 77 14 0.182 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0009891 Not Cancer Driver No 47 0.141 138 17 0.123 0
GNL3 GNL3 Q9BVP2 Guanine nucleotide-binding protein-like 3 chr3 GO:0009891 Not Cancer Driver No 56 0.102 257 21 0.082 0
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0009891 Not Cancer Driver No 115 0.115 854 96 0.112 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0009891 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0009891 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 GO:0009891 Not Cancer Driver No 52 0.105 51 9 0.176 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0009891 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0009891 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0009891 Not Cancer Driver No 88 0.094 190 15 0.079 13
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0009891 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCA1B GUCA1B Q9UMX6 Guanylyl cyclase-activating protein 2 chr6 GO:0009891 Not Cancer Driver No 26 0.13 2 0 0.0 1
GUCA1C GUCA1C O95843 Guanylyl cyclase-activating protein 3 chr3 GO:0009891 Not Cancer Driver No 60 0.287 35 6 0.171 0
GUCA2A GUCA2A Q02747 Guanylin chr1 GO:0009891 Not Cancer Driver No 15 0.13 18 1 0.056 0
GUCA2B GUCA2B Q16661 Guanylate cyclase activator 2B chr1 GO:0009891 Not Cancer Driver No 17 0.152 0 0 0.0 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0009891 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0009891 Not Cancer Driver No 100 0.181 17 7 0.412 0
HBB HBB P68871 Hemoglobin subunit beta chr11 GO:0009891 Not Cancer Driver No 45 0.306 7 2 0.286 5
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0009891 Not Cancer Driver No 46 0.094 145 14 0.097 0
HEATR1 HEATR1 Q9H583 HEAT repeat-containing protein 1 chr1 GO:0009891 Not Cancer Driver No 291 0.136 43 5 0.116 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0009891 Compendium Yes 233 0.32 43 16 0.372 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0009891 Census Yes 118 0.143 435 51 0.117 0
HMBOX1_ENST00000397358 HMBOX1 Q6NT76 Homeobox-containing protein 1 chr8 GO:0009891 Not Cancer Driver No 55 0.131 319 41 0.129 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0009891 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0009891 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0009891 Not Cancer Driver No 77 0.093 504 45 0.089 0
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0009891 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD17B13 HSD17B13 Q7Z5P4 17-beta-hydroxysteroid dehydrogenase 13 chr4 GO:0009891 Not Cancer Driver No 45 0.15 0 0 0.0 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009891 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0009891 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0009891 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0009891 Not Cancer Driver No 73 0.112 282 35 0.124 0
HSPH1_ENST00000320027 HSPH1 Q92598 Heat shock protein 105 kDa chr13 GO:0009891 Not Cancer Driver No 103 0.12 323 42 0.13 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0009891 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0009891 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0009891 Not Cancer Driver No 140 0.306 40 11 0.275 0
ICE1 ICE1 Q9Y2F5 Little elongation complex subunit 1 chr5 GO:0009891 Not Cancer Driver No 360 0.159 1666 265 0.159 0
ICE2 ICE2 Q659A1 Little elongation complex subunit 2 chr15 GO:0009891 Not Cancer Driver No 107 0.109 399 45 0.113 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0009891 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0009891 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0009891 Not Cancer Driver No 24 0.12 49 8 0.163 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0009891 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0009891 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2BP1 IGF2BP1 Q9NZI8 Insulin-like growth factor 2 mRNA-binding protein 1 chr17 GO:0009891 Not Cancer Driver No 141 0.244 298 80 0.268 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0009891 Not Cancer Driver No 39 0.217 44 12 0.273 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0009891 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0009891 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL15_ENST00000320650 IL15 P40933 Interleukin-15 chr4 GO:0009891 Not Cancer Driver No 25 0.154 6 1 0.167 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0009891 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0009891 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL33 IL33 O95760 Interleukin-33 chr9 GO:0009891 Not Cancer Driver No 47 0.174 47 8 0.17 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0009891 Not Cancer Driver No 18 0.118 0 0 0.0 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0009891 Not Cancer Driver No 49 0.153 84 12 0.143 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0009891 Compendium Yes 173 0.111 682 76 0.111 0
INS INS P01308 Insulin chr11 GO:0009891 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0009891 Not Cancer Driver No 190 0.137 280 57 0.204 64
IPPK IPPK Q9H8X2 Inositol-pentakisphosphate 2-kinase chr9 GO:0009891 Not Cancer Driver No 55 0.112 43 3 0.07 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0009891 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0009891 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0009891 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0009891 Not Cancer Driver No 292 0.275 114 26 0.228 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0009891 Census, Compendium Yes 136 0.12 59 5 0.085 5
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0009891 Census, Compendium Yes 167 0.149 63 10 0.159 7
JMJD4 JMJD4 Q9H9V9 2-oxoglutarate and iron-dependent oxygenase JMJD4 chr1 GO:0009891 Not Cancer Driver No 67 0.145 19 5 0.263 0
JUN JUN P05412 Transcription factor Jun chr1 GO:0009891 Census Yes 35 0.106 281 25 0.089 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0009891 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0009891 Not Cancer Driver No 107 0.129 266 27 0.102 0
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0009891 Census, Compendium Yes 357 0.263 275 55 0.2 2
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0009891 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF5 KLF5 Q13887 Krueppel-like factor 5 chr13 GO:0009891 Compendium Yes 77 0.168 366 40 0.109 0
KLRK1 KLRK1 P26718 NKG2-D type II integral membrane protein chr12 GO:0009891 Not Cancer Driver No 38 0.176 0 0 0.0 0
LARP6 LARP6 Q9BRS8 La-related protein 6 chr15 GO:0009891 Not Cancer Driver No 64 0.13 329 48 0.146 0
LARP7_ENST00000344442 LARP7 Q4G0J3 La-related protein 7 chr4 GO:0009891 Not Cancer Driver No 58 0.1 350 44 0.126 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0009891 Compendium Yes 56 0.136 177 29 0.164 0
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0009891 Not Cancer Driver No 119 0.138 63 3 0.048 104
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0009891 Not Cancer Driver No 181 0.259 12 8 0.667 25
LIN28A_ENST00000254231 LIN28A Q9H9Z2 Protein lin-28 homolog A chr1 GO:0009891 Not Cancer Driver No 37 0.177 86 12 0.14 0
LPGAT1 LPGAT1 Q92604 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 chr1 GO:0009891 Not Cancer Driver No 38 0.103 11 0 0.0 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0009891 Not Cancer Driver No 519 0.205 90 17 0.189 23
LYAR_ENST00000452476 LYAR Q9NX58 Cell growth-regulating nucleolar protein chr4 GO:0009891 Not Cancer Driver No 50 0.132 249 31 0.124 0
MAML1 MAML1 Q92585 Mastermind-like protein 1 chr5 GO:0009891 Not Cancer Driver No 102 0.1 1009 102 0.101 0
MAML2 MAML2 Q8IZL2 Mastermind-like protein 2 chr11 GO:0009891 Census, Compendium Yes 146 0.126 1156 146 0.126 0
MAML3 MAML3 Q96JK9 Mastermind-like protein 3 chr4 GO:0009891 Not Cancer Driver No 123 0.108 1119 123 0.11 0
MAP2K3 MAP2K3 P46734 Dual specificity mitogen-activated protein kinase kinase 3 chr17 GO:0009891 Not Cancer Driver No 104 0.3 75 27 0.36 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0009891 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0009891 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0009891 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0009891 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0009891 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0009891 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0009891 Not Cancer Driver No 92 0.113 490 50 0.102 0
MAPKAPK5 MAPKAPK5 Q8IW41 MAP kinase-activated protein kinase 5 chr12 GO:0009891 Not Cancer Driver No 51 0.108 101 12 0.119 0
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0009891 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0009891 Not Cancer Driver No 47 0.145 5 2 0.4 0
MBTPS2 MBTPS2 O43462 Membrane-bound transcription factor site-2 protease chrX GO:0009891 Not Cancer Driver No 63 0.121 16 4 0.25 9
MEPCE MEPCE Q7L2J0 7SK snRNA methylphosphate capping enzyme chr7 GO:0009891 Not Cancer Driver No 76 0.11 446 42 0.094 0
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0009891 Not Cancer Driver No 74 0.128 274 29 0.106 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0009891 Not Cancer Driver No 61 0.112 36 4 0.111 7
MICAL2_ENST00000646065 MICAL2 O94851 [F-actin]-monooxygenase MICAL2 chr11 GO:0009891 Not Cancer Driver No 297 0.152 1191 179 0.15 0
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0009891 Not Cancer Driver No 23 0.126 83 6 0.072 0
MLXIPL MLXIPL Q9NP71 Carbohydrate-responsive element-binding protein chr7 GO:0009891 Not Cancer Driver No 106 0.124 554 66 0.119 0
MMP8 MMP8 P22894 Neutrophil collagenase chr11 GO:0009891 Not Cancer Driver No 73 0.156 115 19 0.165 0
MPV17L2 MPV17L2 Q567V2 Mpv17-like protein 2 chr19 GO:0009891 Not Cancer Driver No 22 0.107 0 0 0.0 0
MRPS27_ENST00000261413 MRPS27 Q92552 28S ribosomal protein S27, mitochondrial chr5 GO:0009891 Not Cancer Driver No 46 0.111 51 7 0.137 0
MRTFA_ENST00000407029 MRTFA Q969V6 Myocardin-related transcription factor A chr22 GO:0009891 Census Yes 131 0.141 843 123 0.146 0
MRTFB MRTFB Q9ULH7 Myocardin-related transcription factor B chr16 GO:0009891 Not Cancer Driver No 124 0.114 1041 116 0.111 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0009891 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0009891 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0009891 Census Yes 40 0.032 1050 19 0.018 0
MYBBP1A_ENST00000254718 MYBBP1A Q9BQG0 Myb-binding protein 1A chr17 GO:0009891 Not Cancer Driver No 144 0.108 463 47 0.102 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009891 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0009891 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0009891 Census Yes 45 0.141 246 33 0.134 0
NAF1 NAF1 Q96HR8 H/ACA ribonucleoprotein complex non-core subunit NAF1 chr4 GO:0009891 Not Cancer Driver No 61 0.123 386 44 0.114 0
NAMPT NAMPT P43490 Nicotinamide phosphoribosyltransferase chr7 GO:0009891 Not Cancer Driver No 50 0.102 27 5 0.185 0
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0009891 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0009891 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCL NCL P19338 Nucleolin chr2 GO:0009891 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA1_ENST00000348332 NCOA1 Q15788 Nuclear receptor coactivator 1 chr2 GO:0009891 Census, Compendium Yes 188 0.13 1217 149 0.122 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0009891 Not Cancer Driver No 94 0.133 72 11 0.153 1
NEK2 NEK2 P51955 Serine/threonine-protein kinase Nek2 chr1 GO:0009891 Not Cancer Driver No 61 0.137 92 19 0.207 0
NEK7 NEK7 Q8TDX7 Serine/threonine-protein kinase Nek7 chr1 GO:0009891 Not Cancer Driver No 35 0.116 23 0 0.0 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009891 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0009891 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0009891 Not Cancer Driver No 57 0.133 172 25 0.145 0
NGRN NGRN Q9NPE2 Neugrin chr15 GO:0009891 Not Cancer Driver No 26 0.089 215 21 0.098 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0009891 Not Cancer Driver No 48 0.148 181 22 0.122 55
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0009891 Not Cancer Driver No 262 0.14 114 19 0.167 0
NLRP12_ENST00000324134 NLRP12 P59046 NACHT, LRR and PYD domains-containing protein 12 chr19 GO:0009891 Not Cancer Driver No 310 0.292 116 43 0.371 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0009891 Not Cancer Driver No 51 0.193 5 1 0.2 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0009891 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOL11 NOL11 Q9H8H0 Nucleolar protein 11 chr17 GO:0009891 Not Cancer Driver No 76 0.106 54 9 0.167 0
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0009891 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0009891 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0009891 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0009891 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0009891 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0009891 Not Cancer Driver No 336 0.168 464 79 0.17 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0009891 Not Cancer Driver No 101 0.179 18 8 0.444 0
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0009891 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0009891 Not Cancer Driver No 90 0.159 218 33 0.151 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0009891 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H2_ENST00000593926 NR1H2 P55055 Oxysterols receptor LXR-beta chr19 GO:0009891 Not Cancer Driver No 56 0.122 179 30 0.168 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0009891 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0009891 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0009891 Not Cancer Driver No 92 0.118 362 37 0.102 12
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0009891 Not Cancer Driver No 85 0.203 23 1 0.043 0
NVL NVL O15381 Nuclear valosin-containing protein-like chr1 GO:0009891 Not Cancer Driver No 90 0.105 267 31 0.116 0
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0009891 Not Cancer Driver No 39 0.097 6 1 0.167 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0009891 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0009891 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0009891 Not Cancer Driver No 50 0.152 10 5 0.5 0
PABPC1 PABPC1 P11940 Polyadenylate-binding protein 1 chr8 GO:0009891 Census, Compendium Yes 100 0.157 317 55 0.174 0
PAIP1 PAIP1 Q9H074 Polyadenylate-binding protein-interacting protein 1 chr5 GO:0009891 Not Cancer Driver No 67 0.14 259 36 0.139 0
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0009891 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAOX PAOX Q6QHF9 Peroxisomal N(1)-acetyl-spermine/spermidine oxidase chr10 GO:0009891 Not Cancer Driver No 70 0.137 29 0 0.0 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0009891 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARM1 PARM1 Q6UWI2 Prostate androgen-regulated mucin-like protein 1 chr4 GO:0009891 Not Cancer Driver No 72 0.232 227 55 0.242 0
PARN PARN O95453 Poly(A)-specific ribonuclease PARN chr16 GO:0009891 Not Cancer Driver No 71 0.111 197 22 0.112 2
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0009891 Not Cancer Driver No 35 0.103 327 33 0.101 0
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0009891 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0009891 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0009891 Census Yes 37 0.154 99 22 0.222 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0009891 Census, Compendium Yes 164 0.148 231 44 0.19 7
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0009891 Not Cancer Driver No 154 0.145 603 93 0.154 1
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0009891 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0009891 Not Cancer Driver No 30 0.103 157 13 0.083 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0009891 Not Cancer Driver No 57 0.098 99 13 0.131 23
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0009891 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKIB_ENST00000368448 PKIB Q9C010 cAMP-dependent protein kinase inhibitor beta chr6 GO:0009891 Not Cancer Driver No 13 0.167 78 13 0.167 0
PKM_ENST00000335181 PKM P14618 Pyruvate kinase PKM chr15 GO:0009891 Not Cancer Driver No 78 0.147 58 13 0.224 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0009891 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0009891 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0009891 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0009891 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLIN5 PLIN5 Q00G26 Perilipin-5 chr19 GO:0009891 Not Cancer Driver No 49 0.106 192 21 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0009891 Not Cancer Driver No 53 0.102 177 23 0.13 4
POLG2 POLG2 Q9UHN1 DNA polymerase subunit gamma-2, mitochondrial chr17 GO:0009891 Not Cancer Driver No 64 0.132 46 4 0.087 3
POMT1 POMT1 Q9Y6A1 Protein O-mannosyl-transferase 1 chr9 GO:0009891 Not Cancer Driver No 75 0.1 55 5 0.091 10
POMT2 POMT2 Q9UKY4 Protein O-mannosyl-transferase 2 chr14 GO:0009891 Not Cancer Driver No 84 0.112 60 3 0.05 15
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0009891 Not Cancer Driver No 62 0.092 93 4 0.043 9
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0009891 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0009891 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0009891 Census Yes 72 0.143 44 4 0.091 3
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0009891 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0009891 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0009891 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0009891 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0009891 Not Cancer Driver No 100 0.118 240 33 0.138 0
PRIM2 PRIM2 P49643 DNA primase large subunit chr6 GO:0009891 Not Cancer Driver No 180 0.354 69 57 0.826 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009891 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009891 Compendium Yes 79 0.117 43 9 0.209 0
PRKCQ PRKCQ Q04759 Protein kinase C theta type chr10 GO:0009891 Not Cancer Driver No 147 0.208 28 9 0.321 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0009891 Compendium Yes 118 0.134 246 34 0.138 0
PRL PRL P01236 Prolactin chr6 GO:0009891 Not Cancer Driver No 49 0.216 22 1 0.045 0
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0009891 Not Cancer Driver No 50 0.135 18 1 0.056 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0009891 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGES3_ENST00000262033 PTGES3 Q15185 Prostaglandin E synthase 3 chr12 GO:0009891 Not Cancer Driver No 11 0.069 52 3 0.058 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0009891 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0009891 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTH1R_ENST00000449590 PTH1R Q03431 Parathyroid hormone/parathyroid hormone-related peptide receptor chr3 GO:0009891 Not Cancer Driver No 86 0.145 124 25 0.202 5
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0009891 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0009891 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTX3 PTX3 P26022 Pentraxin-related protein PTX3 chr3 GO:0009891 Not Cancer Driver No 39 0.102 74 2 0.027 0
PWP1 PWP1 Q13610 Periodic tryptophan protein 1 homolog chr12 GO:0009891 Not Cancer Driver No 51 0.102 186 22 0.118 0
PXYLP1 PXYLP1 Q8TE99 2-phosphoxylose phosphatase 1 chr3 GO:0009891 Not Cancer Driver No 63 0.131 32 13 0.406 0
RAB27A_ENST00000336787 RAB27A P51159 Ras-related protein Rab-27A chr15 GO:0009891 Not Cancer Driver No 25 0.113 15 4 0.267 3
RAB38 RAB38 P57729 Ras-related protein Rab-38 chr11 GO:0009891 Not Cancer Driver No 27 0.128 0 0 0.0 0
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0009891 Not Cancer Driver No 123 0.125 294 32 0.109 2
RAB3GAP2 RAB3GAP2 Q9H2M9 Rab3 GTPase-activating protein non-catalytic subunit chr1 GO:0009891 Not Cancer Driver No 168 0.121 143 17 0.119 2
RAMP1 RAMP1 O60894 Receptor activity-modifying protein 1 chr2 GO:0009891 Not Cancer Driver No 16 0.108 0 0 0.0 0
RASL11A RASL11A Q6T310 Ras-like protein family member 11A chr13 GO:0009891 Not Cancer Driver No 31 0.128 40 6 0.15 0
RBM15 RBM15 Q96T37 RNA-binding protein 15 chr1 GO:0009891 Census, Compendium Yes 118 0.121 686 91 0.133 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0009891 Not Cancer Driver No 49 0.098 151 19 0.126 2
RCC1L RCC1L Q96I51 RCC1-like G exchanging factor-like protein chr7 GO:0009891 Not Cancer Driver No 19 0.041 87 7 0.08 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0009891 Not Cancer Driver No 37 0.185 24 5 0.208 0
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0009891 Not Cancer Driver No 33 0.097 8 0 0.0 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009891 Compendium Yes 75 0.136 400 48 0.12 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0009891 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0009891 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0009891 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0009891 Not Cancer Driver No 38 0.112 20 1 0.05 0
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0009891 Not Cancer Driver No 9 0.066 81 7 0.086 0
RGN RGN Q15493 Regucalcin chrX GO:0009891 Not Cancer Driver No 38 0.127 14 3 0.214 0
RMND1 RMND1 Q9NWS8 Required for meiotic nuclear division protein 1 homolog chr6 GO:0009891 Not Cancer Driver No 46 0.102 83 11 0.133 1
RPS9_ENST00000391752 RPS9 P46781 40S ribosomal protein S9 chr19 GO:0009891 Not Cancer Driver No 23 0.119 34 5 0.147 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0009891 Not Cancer Driver No 176 0.132 241 21 0.087 0
RPUSD3 RPUSD3 Q6P087 Mitochondrial mRNA pseudouridine synthase RPUSD3 chr3 GO:0009891 Not Cancer Driver No 33 0.094 85 5 0.059 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0009891 Not Cancer Driver No 54 0.143 97 15 0.155 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0009891 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX2_ENST00000647337 RUNX2 Q13950 Runt-related transcription factor 2 chr6 GO:0009891 Not Cancer Driver No 83 0.159 447 73 0.163 47
SCAP SCAP Q12770 Sterol regulatory element-binding protein cleavage-activating protein chr3 GO:0009891 Not Cancer Driver No 145 0.113 329 36 0.109 0
SCARB1_ENST00000415380 SCARB1 Q8WTV0 Scavenger receptor class B member 1 chr12 GO:0009891 Not Cancer Driver No 53 0.096 6 1 0.167 0
SERPINB7 SERPINB7 O75635 Serpin B7 chr18 GO:0009891 Not Cancer Driver No 100 0.263 30 8 0.267 0
SERPINF2_ENST00000382061 SERPINF2 P08697 Alpha-2-antiplasmin chr17 GO:0009891 Not Cancer Driver No 62 0.126 112 21 0.188 1
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0009891 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0009891 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SF3B1 SF3B1 O75533 Splicing factor 3B subunit 1 chr2 GO:0009891 Census, Compendium Yes 244 0.187 477 80 0.168 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009891 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT3 SIRT3 Q9NTG7 NAD-dependent protein deacetylase sirtuin-3, mitochondrial chr11 GO:0009891 Not Cancer Driver No 33 0.083 60 2 0.033 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0009891 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0009891 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0009891 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC25A37 SLC25A37 Q9NYZ2 Mitoferrin-1 chr8 GO:0009891 Not Cancer Driver No 45 0.133 68 5 0.074 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0009891 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0009891 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0009891 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC45A3 SLC45A3 Q96JT2 Solute carrier family 45 member 3 chr1 GO:0009891 Census, Compendium Yes 75 0.136 25 6 0.24 0
SLC51B SLC51B Q86UW2 Organic solute transporter subunit beta chr15 GO:0009891 Not Cancer Driver No 9 0.07 58 5 0.086 0
SLC5A3 SLC5A3 P53794 Sodium/myo-inositol cotransporter chr21 GO:0009891 Not Cancer Driver No 81 0.113 73 6 0.082 0
SLC6A9 SLC6A9 P48067 Sodium- and chloride-dependent glycine transporter 1 chr1 GO:0009891 Not Cancer Driver No 102 0.144 65 12 0.185 1
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0009891 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0009891 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0009891 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0009891 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0009891 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMAD9 SMAD9 O15198 Mothers against decapentaplegic homolog 9 chr13 GO:0009891 Not Cancer Driver No 79 0.169 132 14 0.106 1
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0009891 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0009891 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0009891 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0009891 Not Cancer Driver No 82 0.184 216 52 0.241 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0009891 Not Cancer Driver No 21 0.15 107 13 0.121 5
SOAT1 SOAT1 P35610 Sterol O-acyltransferase 1 chr1 GO:0009891 Not Cancer Driver No 73 0.133 49 4 0.082 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0009891 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0009891 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SP1 SP1 P08047 Transcription factor Sp1 chr12 GO:0009891 Not Cancer Driver No 96 0.122 599 71 0.119 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0009891 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0009891 Not Cancer Driver No 46 0.17 187 34 0.182 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0009891 Census Yes 53 0.099 130 11 0.085 1
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0009891 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0009891 Not Cancer Driver No 124 0.109 357 43 0.12 0
SRF SRF P11831 Serum response factor chr6 GO:0009891 Not Cancer Driver No 44 0.087 443 42 0.095 0
SSBP1_ENST00000484178 SSBP1 Q04837 Single-stranded DNA-binding protein, mitochondrial chr7 GO:0009891 Not Cancer Driver No 27 0.182 0 0 0.0 6
STAR STAR P49675 Steroidogenic acute regulatory protein, mitochondrial chr8 GO:0009891 Not Cancer Driver No 45 0.158 85 10 0.118 7
STARD4_ENST00000505803 STARD4 Q96DR4 StAR-related lipid transfer protein 4 chr5 GO:0009891 Not Cancer Driver No 48 0.234 0 0 0.0 0
STAT1 STAT1 P42224 Signal transducer and activator of transcription 1-alpha/beta chr2 GO:0009891 Not Cancer Driver No 131 0.175 144 25 0.174 26
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0009891 Census, Compendium Yes 110 0.143 152 15 0.099 19
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009891 Census, Compendium Yes 75 0.173 135 14 0.104 9
STOML2 STOML2 Q9UJZ1 Stomatin-like protein 2, mitochondrial chr9 GO:0009891 Not Cancer Driver No 40 0.112 117 9 0.077 0
SUCO_ENST00000263688 SUCO Q9UBS9 SUN domain-containing ossification factor chr1 GO:0009891 Not Cancer Driver No 164 0.131 785 99 0.126 0
SVIP SVIP Q8NHG7 Small VCP/p97-interacting protein chr11 GO:0009891 Not Cancer Driver No 16 0.208 77 16 0.208 0
SYNCRIP SYNCRIP O60506 Heterogeneous nuclear ribonucleoprotein Q chr6 GO:0009891 Not Cancer Driver No 93 0.149 285 39 0.137 0
TAZ_ENST00000612460 TAFAZZIN Q16635 Tafazzin chrX GO:0009891 Not Cancer Driver No 33 0.126 12 0 0.0 10
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0009891 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0009891 Census, Compendium Yes 122 0.197 516 93 0.18 0
TCP1 TCP1 P17987 T-complex protein 1 subunit alpha chr6 GO:0009891 Not Cancer Driver No 54 0.097 55 10 0.182 0
TEAD1_ENST00000638666 TEAD1 P28347 Transcriptional enhancer factor TEF-1 chr11 GO:0009891 Not Cancer Driver No 52 0.122 157 24 0.153 1
TENT4A_ENST00000230859 TENT4A Q5XG87 Terminal nucleotidyltransferase 4A chr5 GO:0009891 Not Cancer Driver No 106 0.137 442 43 0.097 0
TERT TERT O14746 Telomerase reverse transcriptase chr5 GO:0009891 Census Yes 110 0.097 212 16 0.075 31
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009891 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0009891 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0009891 Not Cancer Driver No 45 0.109 96 14 0.146 1
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0009891 Not Cancer Driver No 92 0.129 443 66 0.149 1
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0009891 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0009891 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0009891 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0009891 Not Cancer Driver No 141 0.137 35 3 0.086 0
TMEM106A TMEM106A Q96A25 Transmembrane protein 106A chr17 GO:0009891 Not Cancer Driver No 26 0.099 9 1 0.111 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0009891 Census Yes 7 0.159 44 7 0.159 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009891 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0009891 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0009891 Not Cancer Driver No 117 0.1 255 24 0.094 0
TOB1 TOB1 P50616 Protein Tob1 chr17 GO:0009891 Not Cancer Driver No 35 0.101 214 18 0.084 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0009891 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0009891 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0009891 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0009891 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRUB2 TRUB2 O95900 Pseudouridylate synthase TRUB2, mitochondrial chr9 GO:0009891 Not Cancer Driver No 37 0.112 73 7 0.096 0
TYRP1 TYRP1 P17643 5,6-dihydroxyindole-2-carboxylic acid oxidase chr9 GO:0009891 Not Cancer Driver No 81 0.151 87 13 0.149 2
UBTF UBTF P17480 Nucleolar transcription factor 1 chr17 GO:0009891 Not Cancer Driver No 100 0.131 567 77 0.136 1
UCN UCN P55089 Urocortin chr2 GO:0009891 Not Cancer Driver No 7 0.056 61 4 0.066 0
UQCC2 UQCC2 Q9BRT2 Ubiquinol-cytochrome-c reductase complex assembly factor 2 chr6 GO:0009891 Not Cancer Driver No 10 0.079 41 1 0.024 0
USF1 USF1 P22415 Upstream stimulatory factor 1 chr1 GO:0009891 Not Cancer Driver No 52 0.168 271 44 0.162 0
USF2 USF2 Q15853 Upstream stimulatory factor 2 chr19 GO:0009891 Not Cancer Driver No 30 0.087 326 29 0.089 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0009891 Not Cancer Driver No 98 0.119 394 42 0.107 0
UTP15 UTP15 Q8TED0 U3 small nucleolar RNA-associated protein 15 homolog chr5 GO:0009891 Not Cancer Driver No 49 0.095 39 4 0.103 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0009891 Not Cancer Driver No 88 0.109 186 16 0.086 16
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0009891 Not Cancer Driver No 27 0.116 41 7 0.171 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0009891 Not Cancer Driver No 84 0.18 316 57 0.18 1
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0009891 Not Cancer Driver No 68 0.085 99 9 0.091 1
WDR43 WDR43 Q15061 WD repeat-containing protein 43 chr2 GO:0009891 Not Cancer Driver No 57 0.084 216 18 0.083 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:0009891 Not Cancer Driver No 30 0.09 35 3 0.086 0
WDR75 WDR75 Q8IWA0 WD repeat-containing protein 75 chr2 GO:0009891 Not Cancer Driver No 67 0.081 87 7 0.08 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0009891 Not Cancer Driver No 30 0.085 39 4 0.103 4
WRAP53 WRAP53 Q9BUR4 Telomerase Cajal body protein 1 chr17 GO:0009891 Not Cancer Driver No 66 0.12 232 29 0.125 4
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0009891 Not Cancer Driver No 19 0.073 169 9 0.053 0
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0009891 Not Cancer Driver No 87 0.119 118 11 0.093 0
YBX1 YBX1 P67809 Y-box-binding protein 1 chr1 GO:0009891 Not Cancer Driver No 41 0.127 312 41 0.131 0
YBX3 YBX3 P16989 Y-box-binding protein 3 chr12 GO:0009891 Not Cancer Driver No 49 0.132 359 47 0.131 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0009891 Not Cancer Driver No 67 0.116 376 44 0.117 0
ZBTB20 ZBTB20 Q9HC78 Zinc finger and BTB domain-containing protein 20 chr3 GO:0009891 Compendium Yes 151 0.204 433 80 0.185 4
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0009891 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZCCHC13 ZCCHC13 Q8WW36 Zinc finger CCHC domain-containing protein 13 chrX GO:0009891 Not Cancer Driver No 44 0.265 13 5 0.385 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0009891 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZNF143 ZNF143 P52747 Zinc finger protein 143 chr11 GO:0009891 Not Cancer Driver No 67 0.105 425 49 0.115 0
ZNF205_ENST00000382192 ZNF205 O95201 Zinc finger protein 205 chr16 GO:0009891 Not Cancer Driver No 74 0.134 367 49 0.134 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0009891 Not Cancer Driver No 38 0.083 291 27 0.093 0