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Total number of protein in "GO:0009725" GO term:  396

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0009725 Not Cancer Driver No 260 0.176 144 22 0.153 0
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0009725 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0009725 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0009725 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0009725 Not Cancer Driver No 54 0.127 8 1 0.125 0
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0009725 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0009725 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0009725 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0009725 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0009725 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0009725 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0009725 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0009725 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0009725 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0009725 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0009725 Not Cancer Driver No 130 0.279 40 8 0.2 0
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:0009725 Not Cancer Driver No 182 0.119 143 23 0.161 1
AGT AGT P01019 Angiotensinogen chr1 GO:0009725 Not Cancer Driver No 85 0.179 33 10 0.303 1
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0009725 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0009725 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0009725 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0009725 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0009725 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0009725 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0009725 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0009725 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0009725 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0009725 Not Cancer Driver No 80 0.153 184 39 0.212 113
ANG ANG P03950 Angiogenin chr14 GO:0009725 Not Cancer Driver No 19 0.129 36 2 0.056 14
ANGPTL3 ANGPTL3 Q9Y5C1 Angiopoietin-related protein 3 chr1 GO:0009725 Not Cancer Driver No 52 0.113 154 26 0.169 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0009725 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0009725 Not Cancer Driver No 53 0.164 22 4 0.182 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0009725 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0009725 Not Cancer Driver No 1022 0.224 315 72 0.229 3
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0009725 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0009725 Not Cancer Driver No 50 0.155 30 9 0.3 0
AR AR P10275 Androgen receptor chrX GO:0009725 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0009725 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0009725 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0009725 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARPC1B_ENST00000431816 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 GO:0009725 Not Cancer Driver No 37 0.099 34 1 0.029 0
ARSB ARSB P15848 Arylsulfatase B chr5 GO:0009725 Not Cancer Driver No 59 0.111 81 6 0.074 29
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 GO:0009725 Not Cancer Driver No 95 0.151 293 39 0.133 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0009725 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0009725 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0009725 Not Cancer Driver No 66 0.119 23 5 0.217 2
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0009725 Not Cancer Driver No 105 0.251 68 25 0.368 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0009725 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0009725 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0009725 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 GO:0009725 Not Cancer Driver No 47 0.12 23 3 0.13 5
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0009725 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0009725 Census, Compendium Yes 24 0.1 72 5 0.069 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0009725 Not Cancer Driver No 13 0.13 21 2 0.095 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0009725 Not Cancer Driver No 95 0.185 226 51 0.226 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0009725 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0009725 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0009725 Census Yes 174 0.139 397 59 0.149 6
C2 C2 P06681 Complement C2 chr6 GO:0009725 Not Cancer Driver No 120 0.16 120 17 0.142 3
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0009725 Not Cancer Driver No 31 0.091 43 5 0.116 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0009725 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0009725 Not Cancer Driver No 17 0.114 115 10 0.087 3
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0009725 Census Yes 32 0.116 62 5 0.081 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0009725 Census Yes 49 0.118 71 7 0.099 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0009725 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0009725 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0009725 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0009725 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0009725 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0009725 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0009725 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0009725 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0009725 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0009725 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0009725 Not Cancer Driver No 37 0.185 43 4 0.093 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0009725 Not Cancer Driver No 40 0.083 44 2 0.045 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0009725 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0009725 Not Cancer Driver No 23 0.085 230 18 0.078 0
CITED4 CITED4 Q96RK1 Cbp/p300-interacting transactivator 4 chr1 GO:0009725 Not Cancer Driver No 1 0.005 170 1 0.006 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0009725 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0009725 Not Cancer Driver No 40 0.191 0 0 0.0 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0009725 Not Cancer Driver No 183 0.264 217 67 0.309 53
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0009725 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0009725 Census Yes 402 0.274 1182 337 0.285 103
CPN1 CPN1 P15169 Carboxypeptidase N catalytic chain chr10 GO:0009725 Not Cancer Driver No 98 0.214 124 27 0.218 1
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0009725 Not Cancer Driver No 368 0.245 73 22 0.301 140
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0009725 Census Yes 25 0.076 277 23 0.083 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0009725 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0009725 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0009725 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0009725 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRLS1 CRLS1 Q9UJA2 Cardiolipin synthase (CMP-forming) chr20 GO:0009725 Not Cancer Driver No 18 0.06 36 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0009725 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSN1S1 CSN1S1 P47710 Alpha-S1-casein chr4 GO:0009725 Not Cancer Driver No 31 0.168 109 16 0.147 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0009725 Census Yes 126 0.139 268 35 0.131 4
CTSB CTSB P07858 Cathepsin B chr8 GO:0009725 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0009725 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0009725 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0009725 Not Cancer Driver No 54 0.163 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009725 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0009725 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 GO:0009725 Not Cancer Driver No 65 0.2 35 8 0.229 2
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0009725 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0009725 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0009725 Census, Compendium Yes 64 0.185 0 0 0.0 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0009725 Not Cancer Driver No 20 0.086 87 9 0.103 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0009725 Not Cancer Driver No 55 0.107 0 0 0.0 6
DHH DHH O43323 Desert hedgehog protein chr12 GO:0009725 Not Cancer Driver No 36 0.091 57 7 0.123 1
DSG1 DSG1 Q02413 Desmoglein-1 chr18 GO:0009725 Not Cancer Driver No 250 0.238 496 130 0.262 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0009725 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0009725 Not Cancer Driver No 62 0.145 21 6 0.286 2
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0009725 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0009725 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0009725 Not Cancer Driver No 34 0.149 25 6 0.24 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0009725 Not Cancer Driver No 26 0.12 54 6 0.111 0
ENG ENG P17813 Endoglin chr9 GO:0009725 Not Cancer Driver No 60 0.091 114 15 0.132 32
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009725 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0009725 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPO EPO P01588 Erythropoietin chr7 GO:0009725 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0009725 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0009725 Census, Compendium Yes 121 0.203 195 27 0.138 2
F7 F7 P08709 Coagulation factor VII chr13 GO:0009725 Not Cancer Driver No 74 0.159 50 7 0.14 108
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0009725 Not Cancer Driver No 25 0.174 141 24 0.17 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0009725 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0009725 Not Cancer Driver No 54 0.152 0 0 0.0 0
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0009725 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0009725 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0009725 Not Cancer Driver No 84 0.335 97 51 0.526 7
FHL2_ENST00000408995 FHL2 Q14192 Four and a half LIM domains protein 2 chr2 GO:0009725 Not Cancer Driver No 30 0.108 0 0 0.0 0
FIBIN FIBIN Q8TAL6 Fin bud initiation factor homolog chr11 GO:0009725 Not Cancer Driver No 42 0.199 51 12 0.235 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0009725 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOS FOS P01100 Protein c-Fos chr14 GO:0009725 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSB FOSB P53539 Protein FosB chr19 GO:0009725 Not Cancer Driver No 50 0.148 313 44 0.141 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0009725 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0009725 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0009725 Census, Compendium Yes 70 0.104 595 68 0.114 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0009725 Not Cancer Driver No 226 0.325 28 11 0.393 16
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0009725 Not Cancer Driver No 133 0.281 43 14 0.326 2
GAL GAL P22466 Galanin peptides chr11 GO:0009725 Not Cancer Driver No 17 0.138 36 2 0.056 1
GAS2L1_ENST00000621062 GAS2L1 Q99501 GAS2-like protein 1 chr22 GO:0009725 Not Cancer Driver No 76 0.112 474 50 0.105 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0009725 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009725 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0009725 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0009725 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCGR GCGR P47871 Glucagon receptor chr17 GO:0009725 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0009725 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0009725 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0009725 Not Cancer Driver No 32 0.117 31 3 0.097 0
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0009725 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0009725 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0009725 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0009725 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0009725 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLB1 GLB1 P16278 Beta-galactosidase chr3 GO:0009725 Not Cancer Driver No 72 0.106 54 6 0.111 99
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0009725 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0009725 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0009725 Not Cancer Driver No 124 0.224 63 14 0.222 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0009725 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0009725 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:0009725 Not Cancer Driver No 40 0.122 15 1 0.067 14
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0009725 Not Cancer Driver No 56 0.136 35 5 0.143 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0009725 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0009725 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0009725 Not Cancer Driver No 57 0.153 12 0 0.0 0
GPR83 GPR83 Q9NYM4 G-protein coupled receptor 83 chr11 GO:0009725 Not Cancer Driver No 93 0.22 32 10 0.312 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0009725 Not Cancer Driver No 38 0.187 12 1 0.083 0
GSTM3_ENST00000361066 GSTM3 P21266 Glutathione S-transferase Mu 3 chr1 GO:0009725 Not Cancer Driver No 32 0.142 0 0 0.0 0
HAPLN3_ENST00000359595 HAPLN3 Q96S86 Hyaluronan and proteoglycan link protein 3 chr15 GO:0009725 Not Cancer Driver No 61 0.169 31 5 0.161 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0009725 Not Cancer Driver No 103 0.212 446 94 0.211 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0009725 Not Cancer Driver No 37 0.132 226 32 0.142 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0009725 Not Cancer Driver No 92 0.181 29 4 0.138 19
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0009725 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0009725 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0009725 Not Cancer Driver No 35 0.085 339 25 0.074 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0009725 Census, Compendium Yes 37 0.118 205 26 0.127 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0009725 Not Cancer Driver No 60 0.144 12 0 0.0 0
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0009725 Not Cancer Driver No 27 0.067 30 0 0.0 14
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 GO:0009725 Not Cancer Driver No 69 0.185 25 3 0.12 0
HSD3B2_ENST00000369416 HSD3B2 P26439 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 GO:0009725 Not Cancer Driver No 83 0.223 24 9 0.375 28
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009725 Not Cancer Driver No 59 0.112 335 37 0.11 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0009725 Not Cancer Driver No 91 0.233 33 15 0.455 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0009725 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0009725 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0009725 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGFBP7 IGFBP7 Q16270 Insulin-like growth factor-binding protein 7 chr4 GO:0009725 Not Cancer Driver No 22 0.078 100 12 0.12 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0009725 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0009725 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0009725 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0009725 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0009725 Not Cancer Driver No 35 0.165 58 7 0.121 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0009725 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0009725 Not Cancer Driver No 61 0.15 98 5 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0009725 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0009725 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0009725 Not Cancer Driver No 106 0.101 129 18 0.14 3
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0009725 Census, Compendium Yes 136 0.12 59 5 0.085 5
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0009725 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:0009725 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0009725 Not Cancer Driver No 34 0.139 154 24 0.156 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0009725 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 GO:0009725 Not Cancer Driver No 57 0.142 165 19 0.115 0
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0009725 Not Cancer Driver No 43 0.098 28 2 0.071 34
LCN8_ENST00000612714 LCN8 Q6JVE9 Epididymal-specific lipocalin-8 chr9 GO:0009725 Not Cancer Driver No 26 0.149 1 0 0.0 0
LEP LEP P41159 Leptin chr7 GO:0009725 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0009725 Not Cancer Driver No 243 0.209 57 11 0.193 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0009725 Not Cancer Driver No 181 0.259 12 8 0.667 25
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 GO:0009725 Census Yes 35 0.222 14 1 0.071 0
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0009725 Not Cancer Driver No 998 0.214 209 40 0.191 1
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0009725 Census Yes 95 0.186 84 12 0.143 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0009725 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0009725 Not Cancer Driver No 47 0.145 5 2 0.4 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0009725 Not Cancer Driver No 52 0.171 304 52 0.171 0
MC4R MC4R P32245 Melanocortin receptor 4 chr18 GO:0009725 Not Cancer Driver No 57 0.172 2 0 0.0 29
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0009725 Not Cancer Driver No 15 0.105 20 2 0.1 0
ME1 ME1 P48163 NADP-dependent malic enzyme chr6 GO:0009725 Not Cancer Driver No 109 0.191 64 10 0.156 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0009725 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0009725 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0009725 Not Cancer Driver No 54 0.205 47 13 0.277 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0009725 Not Cancer Driver No 25 0.104 207 22 0.106 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0009725 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP19 MMP19 Q99542 Matrix metalloproteinase-19 chr12 GO:0009725 Not Cancer Driver No 94 0.185 98 20 0.204 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0009725 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0009725 Not Cancer Driver No 73 0.071 11 0 0.0 0
MSI1 MSI1 O43347 RNA-binding protein Musashi homolog 1 chr12 GO:0009725 Not Cancer Driver No 45 0.124 133 16 0.12 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0009725 Not Cancer Driver No 68 0.181 64 11 0.172 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009725 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0009725 Census Yes 45 0.141 246 33 0.134 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0009725 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:0009725 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0009725 Not Cancer Driver No 92 0.169 285 39 0.137 12
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009725 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0009725 Not Cancer Driver No 104 0.107 344 38 0.11 0
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0009725 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0009725 Not Cancer Driver No 84 0.308 206 65 0.316 0
NOS1_ENST00000317775 NOS1 P29475 Nitric oxide synthase, brain chr12 GO:0009725 Not Cancer Driver No 405 0.282 342 99 0.289 0
NOS2 NOS2 P35228 Nitric oxide synthase, inducible chr17 GO:0009725 Not Cancer Driver No 207 0.18 201 33 0.164 0
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0009725 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0009725 Census, Compendium Yes 363 0.142 686 87 0.127 3
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0009725 Not Cancer Driver No 229 0.286 429 114 0.266 0
NQO1 NQO1 P15559 NAD(P)H dehydrogenase [quinone] 1 chr16 GO:0009725 Not Cancer Driver No 21 0.077 10 1 0.1 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0009725 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0009725 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0009725 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0009725 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0009725 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0009725 Census Yes 83 0.133 298 37 0.124 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0009725 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0009725 Census, Compendium Yes 249 0.297 57 21 0.368 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0009725 Not Cancer Driver No 22 0.039 52 6 0.115 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0009725 Not Cancer Driver No 117 0.308 18 5 0.278 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0009725 Not Cancer Driver No 80 0.154 39 5 0.128 11
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0009725 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0009725 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0009725 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0009725 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0009725 Not Cancer Driver No 129 0.133 254 37 0.146 0
PAPPA PAPPA Q13219 Pappalysin-1 chr9 GO:0009725 Not Cancer Driver No 370 0.227 239 37 0.155 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0009725 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0009725 Census Yes 84 0.187 291 55 0.189 4
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0009725 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0009725 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0009725 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0009725 Not Cancer Driver No 139 0.185 336 61 0.182 2
PDCD7 PDCD7 Q8N8D1 Programmed cell death protein 7 chr15 GO:0009725 Not Cancer Driver No 47 0.097 275 15 0.055 0
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0009725 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0009725 Not Cancer Driver No 32 0.113 238 23 0.097 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:0009725 Not Cancer Driver No 134 0.119 610 82 0.134 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0009725 Not Cancer Driver No 81 0.172 48 11 0.229 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0009725 Not Cancer Driver No 144 0.192 56 7 0.125 30
PIAS3 PIAS3 Q9Y6X2 E3 SUMO-protein ligase PIAS3 chr1 GO:0009725 Not Cancer Driver No 70 0.111 266 31 0.117 0
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0009725 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0009725 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0009725 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0009725 Not Cancer Driver No 313 0.257 481 104 0.216 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0009725 Not Cancer Driver No 86 0.11 115 10 0.087 2
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0009725 Not Cancer Driver No 50 0.187 198 38 0.192 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0009725 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0009725 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0009725 Not Cancer Driver No 47 0.058 695 35 0.05 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009725 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0009725 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0009725 Census Yes 53 0.151 24 0 0.0 2
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009725 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0009725 Not Cancer Driver No 107 0.145 170 26 0.153 0
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0009725 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0009725 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0009725 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0009725 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0009725 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0009725 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0009725 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0009725 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0009725 Not Cancer Driver No 248 0.172 325 64 0.197 0
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0009725 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0009725 Not Cancer Driver No 20 0.093 14 1 0.071 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0009725 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 GO:0009725 Not Cancer Driver No 57 0.106 218 19 0.087 0
RBM14 RBM14 Q96PK6 RNA-binding protein 14 chr11 GO:0009725 Not Cancer Driver No 99 0.148 350 59 0.169 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0009725 Not Cancer Driver No 71 0.122 297 37 0.125 1
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009725 Compendium Yes 75 0.136 400 48 0.12 0
RERG_ENST00000538313 RERG Q96A58 Ras-related and estrogen-regulated growth inhibitor chr12 GO:0009725 Not Cancer Driver No 42 0.211 39 10 0.256 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0009725 Not Cancer Driver No 142 0.129 868 113 0.13 4
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0009725 Census, Compendium Yes 99 0.513 46 13 0.283 2
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0009725 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0009725 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 GO:0009725 Not Cancer Driver No 21 0.154 13 3 0.231 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0009725 Not Cancer Driver No 45 0.086 226 26 0.115 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0009725 Not Cancer Driver No 12 0.132 14 2 0.143 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0009725 Not Cancer Driver No 31 0.1 259 30 0.116 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0009725 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0009725 Not Cancer Driver No 51 0.122 57 5 0.088 0
SFR1 SFR1 Q86XK3 Swi5-dependent recombination DNA repair protein 1 homolog chr10 GO:0009725 Not Cancer Driver No 21 0.086 109 12 0.11 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0009725 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP4 SFRP4 Q6FHJ7 Secreted frizzled-related protein 4 chr7 GO:0009725 Census Yes 81 0.234 68 22 0.324 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0009725 Census, Compendium Yes 58 0.135 86 16 0.186 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009725 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0009725 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0009725 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0009725 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0009725 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0009725 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC34A2 SLC34A2 O95436 Sodium-dependent phosphate transport protein 2B chr4 GO:0009725 Census Yes 132 0.191 65 15 0.231 1
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0009725 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0009725 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0009725 Not Cancer Driver No 351 0.23 40 9 0.225 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0009725 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0009725 Not Cancer Driver No 59 0.138 2 0 0.0 0
SORD SORD Q00796 Sorbitol dehydrogenase chr15 GO:0009725 Not Cancer Driver No 29 0.081 41 7 0.171 3
SOST SOST Q9BQB4 Sclerostin chr17 GO:0009725 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0009725 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX30 SOX30 O94993 Transcription factor SOX-30 chr5 GO:0009725 Not Cancer Driver No 103 0.137 659 89 0.135 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0009725 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0009725 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0009725 Not Cancer Driver No 48 0.189 0 0 0.0 21
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0009725 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRF SRF P11831 Serum response factor chr6 GO:0009725 Not Cancer Driver No 44 0.087 443 42 0.095 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0009725 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0009725 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0009725 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0009725 Not Cancer Driver No 60 0.165 45 12 0.267 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0009725 Census, Compendium Yes 110 0.143 152 15 0.099 19
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0009725 Not Cancer Driver No 59 0.239 58 12 0.207 0
STEAP2 STEAP2 Q8NFT2 Metalloreductase STEAP2 chr7 GO:0009725 Not Cancer Driver No 68 0.139 1 0 0.0 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009725 Census, Compendium Yes 75 0.173 135 14 0.104 9
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0009725 Not Cancer Driver No 31 0.088 221 22 0.1 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0009725 Not Cancer Driver No 69 0.17 28 2 0.071 0
TAT TAT P17735 Tyrosine aminotransferase chr16 GO:0009725 Not Cancer Driver No 102 0.225 75 21 0.28 1
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0009725 Compendium Yes 61 0.18 285 52 0.182 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009725 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0009725 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0009725 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0009725 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0009725 Not Cancer Driver No 129 0.152 268 41 0.153 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0009725 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0009725 Not Cancer Driver No 188 0.161 320 58 0.181 0
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0009725 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0009725 Not Cancer Driver No 25 0.121 0 0 0.0 0
TIMP2 TIMP2 P16035 Metalloproteinase inhibitor 2 chr17 GO:0009725 Not Cancer Driver No 31 0.141 6 2 0.333 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0009725 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0009725 Not Cancer Driver No 30 0.134 8 2 0.25 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0009725 Not Cancer Driver No 108 0.138 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009725 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11B TNFRSF11B O00300 Tumor necrosis factor receptor superfamily member 11B chr8 GO:0009725 Not Cancer Driver No 79 0.197 17 3 0.176 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0009725 Not Cancer Driver No 28 0.153 1 0 0.0 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0009725 Not Cancer Driver No 59 0.097 140 8 0.057 0
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0009725 Not Cancer Driver No 118 0.241 55 17 0.309 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0009725 Not Cancer Driver No 226 0.188 957 167 0.175 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0009725 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0009725 Census, Compendium Yes 120 0.114 537 61 0.114 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0009725 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 GO:0009725 Not Cancer Driver No 47 0.133 71 13 0.183 0
TSHB_ENST00000369517 TSHB P01222 Thyrotropin subunit beta chr1 GO:0009725 Not Cancer Driver No 34 0.246 0 0 0.0 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0009725 Census Yes 128 0.168 38 9 0.237 39
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0009725 Not Cancer Driver No 5 0.03 1 0 0.0 0
TXN2_ENST00000403313 TXN2 Q99757 Thioredoxin, mitochondrial chr22 GO:0009725 Not Cancer Driver No 22 0.133 34 4 0.118 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0009725 Not Cancer Driver No 61 0.156 77 14 0.182 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0009725 Not Cancer Driver No 22 0.07 41 0 0.0 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0009725 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0009725 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCN UCN P55089 Urocortin chr2 GO:0009725 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0009725 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP3 UCP3 P55916 Mitochondrial uncoupling protein 3 chr11 GO:0009725 Not Cancer Driver No 37 0.119 7 1 0.143 1
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0009725 Not Cancer Driver No 100 0.188 11 2 0.182 55
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:0009725 Not Cancer Driver No 191 0.145 249 29 0.116 0
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0009725 Census, Compendium Yes 122 0.109 602 69 0.115 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0009725 Not Cancer Driver No 26 0.1 102 6 0.059 1
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0009725 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0009725 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0009725 Not Cancer Driver No 55 0.158 11 1 0.091 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0009725 Not Cancer Driver No 19 0.073 169 9 0.053 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0009725 Not Cancer Driver No 51 0.101 489 49 0.1 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0009725 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0009725 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0009725 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0009725 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZNF366 ZNF366 Q8N895 Zinc finger protein 366 chr5 GO:0009725 Not Cancer Driver No 158 0.212 382 85 0.223 0