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Total number of protein in "GO:0009719" GO term:  700

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
A2M A2M P01023 Alpha-2-macroglobulin chr12 GO:0009719 Not Cancer Driver No 260 0.176 144 22 0.153 0
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0009719 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA1 ABCA1 O95477 Phospholipid-transporting ATPase ABCA1 chr9 GO:0009719 Not Cancer Driver No 284 0.126 245 40 0.163 31
ABCA3 ABCA3 Q99758 Phospholipid-transporting ATPase ABCA3 chr16 GO:0009719 Not Cancer Driver No 224 0.131 77 4 0.052 13
ABCB11 ABCB11 O95342 Bile salt export pump chr2 GO:0009719 Not Cancer Driver No 233 0.176 124 24 0.194 21
ABCC1 ABCC1 P33527 Multidrug resistance-associated protein 1 chr16 GO:0009719 Not Cancer Driver No 199 0.13 123 22 0.179 1
ABHD2_ENST00000565973 ABHD2 P08910 Monoacylglycerol lipase ABHD2 chr15 GO:0009719 Not Cancer Driver No 54 0.127 8 1 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0009719 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACAP2 ACAP2 Q15057 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 chr3 GO:0009719 Not Cancer Driver No 97 0.125 287 40 0.139 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0009719 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACOD1 ACOD1 A6NK06 Cis-aconitate decarboxylase chr13 GO:0009719 Not Cancer Driver No 5 0.01 36 0 0.0 0
ACSBG1 ACSBG1 Q96GR2 Long-chain-fatty-acid--CoA ligase ACSBG1 chr15 GO:0009719 Not Cancer Driver No 124 0.171 107 22 0.206 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0009719 Not Cancer Driver No 112 0.299 43 5 0.116 5
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0009719 Not Cancer Driver No 51 0.129 6 2 0.333 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0009719 Census, Compendium Yes 78 0.153 21 8 0.381 8
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0009719 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0009719 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0009719 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0009719 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0009719 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0009719 Not Cancer Driver No 52 0.126 35 4 0.114 0
ADTRP_ENST00000414691 ADTRP Q96IZ2 Androgen-dependent TFPI-regulating protein chr6 GO:0009719 Not Cancer Driver No 41 0.178 2 0 0.0 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0009719 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGL_ENST00000361915 AGL P35573 Glycogen debranching enzyme chr1 GO:0009719 Not Cancer Driver No 182 0.119 143 23 0.161 1
AGT AGT P01019 Angiotensinogen chr1 GO:0009719 Not Cancer Driver No 85 0.179 33 10 0.303 1
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0009719 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIF1 AIF1 P55008 Allograft inflammatory factor 1 chr6 GO:0009719 Not Cancer Driver No 14 0.095 61 6 0.098 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0009719 Not Cancer Driver No 88 0.144 166 22 0.133 11
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0009719 Not Cancer Driver No 383 0.165 1456 240 0.165 0
AKAP8 AKAP8 O43823 A-kinase anchor protein 8 chr19 GO:0009719 Not Cancer Driver No 88 0.127 566 78 0.138 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0009719 Census Yes 474 0.121 2281 268 0.117 1
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0009719 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0009719 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0009719 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0009719 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0009719 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALAD ALAD P13716 Delta-aminolevulinic acid dehydratase chr9 GO:0009719 Not Cancer Driver No 52 0.158 13 3 0.231 5
ALPL ALPL P05186 Alkaline phosphatase, tissue-nonspecific isozyme chr1 GO:0009719 Not Cancer Driver No 80 0.153 184 39 0.212 113
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0009719 Not Cancer Driver No 46 0.093 85 7 0.082 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0009719 Not Cancer Driver No 59 0.171 61 12 0.197 0
ANXA3 ANXA3 P12429 Annexin A3 chr4 GO:0009719 Not Cancer Driver No 53 0.164 22 4 0.182 0
AOC1_ENST00000467291 AOC1 P19801 Amiloride-sensitive amine oxidase [copper-containing] chr7 GO:0009719 Not Cancer Driver No 161 0.214 98 26 0.265 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0009719 Not Cancer Driver No 127 0.102 17 1 0.059 0
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0009719 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0009719 Not Cancer Driver No 146 0.225 455 98 0.215 0
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0009719 Not Cancer Driver No 13 0.13 0 0 0.0 0
APOB APOB P04114 Apolipoprotein B-100 chr2 GO:0009719 Not Cancer Driver No 1022 0.224 315 72 0.229 3
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0009719 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0009719 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0009719 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0009719 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0009719 Not Cancer Driver No 75 0.254 12 0 0.0 0
AR AR P10275 Androgen receptor chrX GO:0009719 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0009719 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0009719 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0009719 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0009719 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARID5A ARID5A Q03989 AT-rich interactive domain-containing protein 5A chr2 GO:0009719 Not Cancer Driver No 64 0.108 373 42 0.113 0
ARPC1B_ENST00000431816 ARPC1B O15143 Actin-related protein 2/3 complex subunit 1B chr7 GO:0009719 Not Cancer Driver No 37 0.099 34 1 0.029 0
ARSB ARSB P15848 Arylsulfatase B chr5 GO:0009719 Not Cancer Driver No 59 0.111 81 6 0.074 29
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0009719 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 GO:0009719 Not Cancer Driver No 95 0.151 293 39 0.133 0
ASS1_ENST00000352480 ASS1 P00966 Argininosuccinate synthase chr9 GO:0009719 Not Cancer Driver No 65 0.158 63 8 0.127 86
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0009719 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0009719 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATP1A3_ENST00000302102 ATP1A3 P13637 Sodium/potassium-transporting ATPase subunit alpha-3 chr19 GO:0009719 Not Cancer Driver No 200 0.197 115 29 0.252 31
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0009719 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0009719 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0009719 Not Cancer Driver No 228 0.152 171 46 0.269 52
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0009719 Not Cancer Driver No 105 0.251 68 25 0.368 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0009719 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0009719 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG4 BAG4 O95429 BAG family molecular chaperone regulator 4 chr8 GO:0009719 Not Cancer Driver No 55 0.12 402 49 0.122 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0009719 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0009719 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCHE BCHE P06276 Cholinesterase chr3 GO:0009719 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCKDHB BCKDHB P21953 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial chr6 GO:0009719 Not Cancer Driver No 47 0.12 23 3 0.13 5
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0009719 Census, Compendium Yes 210 0.251 677 171 0.253 3
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0009719 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0009719 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0009719 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0009719 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0009719 Not Cancer Driver No 45 0.1 190 19 0.1 0
BGLAP BGLAP P02818 Osteocalcin chr1 GO:0009719 Not Cancer Driver No 13 0.13 21 2 0.095 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0009719 Census Yes 153 0.108 667 70 0.105 8
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0009719 Not Cancer Driver No 95 0.185 226 51 0.226 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0009719 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRD8 BRD8 Q9H0E9 Bromodomain-containing protein 8 chr5 GO:0009719 Not Cancer Driver No 189 0.153 934 147 0.157 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0009719 Census Yes 174 0.139 397 59 0.149 6
C2 C2 P06681 Complement C2 chr6 GO:0009719 Not Cancer Driver No 120 0.16 120 17 0.142 3
CAB39 CAB39 Q9Y376 Calcium-binding protein 39 chr2 GO:0009719 Not Cancer Driver No 31 0.091 43 5 0.116 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0009719 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0009719 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0009719 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0009719 Not Cancer Driver No 75 0.125 396 47 0.119 0
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0009719 Not Cancer Driver No 162 0.342 29 9 0.31 0
CALM3_ENST00000596362 CALM3 P0DP25 Calmodulin-3 chr19 GO:0009719 Not Cancer Driver No 17 0.114 115 10 0.087 3
CAMP CAMP P49913 Cathelicidin antimicrobial peptide chr3 GO:0009719 Not Cancer Driver No 25 0.147 48 4 0.083 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0009719 Not Cancer Driver No 81 0.116 46 11 0.239 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0009719 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0009719 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0009719 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0009719 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0009719 Census Yes 49 0.118 71 7 0.099 0
CASQ2 CASQ2 O14958 Calsequestrin-2 chr1 GO:0009719 Not Cancer Driver No 74 0.185 75 16 0.213 4
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0009719 Not Cancer Driver No 304 0.282 189 60 0.317 108
CASTOR1 CASTOR1 Q8WTX7 Cytosolic arginine sensor for mTORC1 subunit 1 chr22 GO:0009719 Not Cancer Driver No 27 0.082 39 5 0.128 0
CASTOR3 CASTOR3 Q8NAP1 Putative protein CASTOR 3 chr7 GO:0009719 Not Cancer Driver No 18 0.11 1 0 0.0 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0009719 Not Cancer Driver No 30 0.169 2 0 0.0 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0009719 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0009719 Not Cancer Driver No 23 0.126 119 18 0.151 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0009719 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCL2 CCL2 P13500 C-C motif chemokine 2 chr17 GO:0009719 Not Cancer Driver No 20 0.202 15 5 0.333 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0009719 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCN2 CCN2 P29279 CCN family member 2 chr6 GO:0009719 Not Cancer Driver No 58 0.166 0 0 0.0 0
CCNA2_ENST00000618014 CCNA2 P20248 Cyclin-A2 chr4 GO:0009719 Not Cancer Driver No 45 0.104 186 19 0.102 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0009719 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0009719 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD36_ENST00000309881 CD36 P16671 Platelet glycoprotein 4 chr7 GO:0009719 Not Cancer Driver No 75 0.159 12 3 0.25 3
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0009719 Not Cancer Driver No 54 0.18 3 1 0.333 0
CD44 CD44 P16070 CD44 antigen chr11 GO:0009719 Not Cancer Driver No 75 0.101 542 60 0.111 0
CD68 CD68 P34810 Macrosialin chr17 GO:0009719 Not Cancer Driver No 26 0.073 192 13 0.068 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0009719 Not Cancer Driver No 28 0.119 0 0 0.0 0
CD9 CD9 P21926 CD9 antigen chr12 GO:0009719 Not Cancer Driver No 22 0.096 0 0 0.0 0
CDC6 CDC6 Q99741 Cell division control protein 6 homolog chr17 GO:0009719 Not Cancer Driver No 57 0.102 170 15 0.088 1
CDH1 CDH1 P12830 Cadherin-1 chr16 GO:0009719 Census, Compendium Yes 150 0.17 400 82 0.205 5
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0009719 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDO1 CDO1 Q16878 Cysteine dioxygenase type 1 chr5 GO:0009719 Not Cancer Driver No 37 0.185 43 4 0.093 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0009719 Not Cancer Driver No 3 0.009 276 2 0.007 0
CES1_ENST00000361503 CES1 P23141 Liver carboxylesterase 1 chr16 GO:0009719 Not Cancer Driver No 138 0.243 41 2 0.049 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0009719 Not Cancer Driver No 40 0.083 44 2 0.045 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0009719 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0009719 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHMP5 CHMP5 Q9NZZ3 Charged multivesicular body protein 5 chr9 GO:0009719 Not Cancer Driver No 24 0.11 195 18 0.092 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0009719 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIB2 CIB2 O75838 Calcium and integrin-binding family member 2 chr15 GO:0009719 Not Cancer Driver No 25 0.134 7 0 0.0 5
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0009719 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0009719 Not Cancer Driver No 23 0.085 230 18 0.078 0
CITED4 CITED4 Q96RK1 Cbp/p300-interacting transactivator 4 chr1 GO:0009719 Not Cancer Driver No 1 0.005 170 1 0.006 0
CLDN1 CLDN1 O95832 Claudin-1 chr3 GO:0009719 Not Cancer Driver No 31 0.147 16 3 0.188 0
CLDN4 CLDN4 O14493 Claudin-4 chr7 GO:0009719 Not Cancer Driver No 40 0.191 0 0 0.0 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0009719 Not Cancer Driver No 183 0.264 217 67 0.309 53
COL16A1 COL16A1 Q07092 Collagen alpha-1(XVI) chain chr1 GO:0009719 Not Cancer Driver No 192 0.12 1381 163 0.118 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0009719 Census, Compendium Yes 247 0.169 1212 214 0.177 148
COL1A2 COL1A2 P08123 Collagen alpha-2(I) chain chr7 GO:0009719 Not Cancer Driver No 372 0.272 1159 329 0.284 83
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0009719 Census Yes 402 0.274 1182 337 0.285 103
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0009719 Not Cancer Driver No 349 0.209 1457 310 0.213 32
COL4A6_ENST00000372216 COL4A6 Q14031 Collagen alpha-6(IV) chain chrX GO:0009719 Not Cancer Driver No 286 0.169 1451 255 0.176 1
COL5A2 COL5A2 P05997 Collagen alpha-2(V) chain chr2 GO:0009719 Not Cancer Driver No 350 0.233 1276 297 0.233 2
COL6A1 COL6A1 P12109 Collagen alpha-1(VI) chain chr21 GO:0009719 Not Cancer Driver No 145 0.141 434 61 0.141 12
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0009719 Not Cancer Driver No 41 0.084 138 10 0.072 0
CPEB1_ENST00000611031 CPEB1 Q9BZB8 Cytoplasmic polyadenylation element-binding protein 1 chr15 GO:0009719 Not Cancer Driver No 90 0.159 226 37 0.164 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0009719 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPEB4 CPEB4 Q17RY0 Cytoplasmic polyadenylation element-binding protein 4 chr5 GO:0009719 Not Cancer Driver No 85 0.117 443 54 0.122 0
CPN1 CPN1 P15169 Carboxypeptidase N catalytic chain chr10 GO:0009719 Not Cancer Driver No 98 0.214 124 27 0.218 1
CPS1_ENST00000233072 CPS1 P31327 Carbamoyl-phosphate synthase [ammonia], mitochondrial chr2 GO:0009719 Not Cancer Driver No 368 0.245 73 22 0.301 140
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0009719 Census Yes 25 0.076 277 23 0.083 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0009719 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0009719 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRHR2_ENST00000471646 CRHR2 Q13324 Corticotropin-releasing factor receptor 2 chr7 GO:0009719 Not Cancer Driver No 79 0.192 0 0 0.0 0
CRK CRK P46108 Adapter molecule crk chr17 GO:0009719 Not Cancer Driver No 30 0.099 197 23 0.117 0
CRLS1 CRLS1 Q9UJA2 Cardiolipin synthase (CMP-forming) chr20 GO:0009719 Not Cancer Driver No 18 0.06 36 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0009719 Not Cancer Driver No 76 0.13 91 5 0.055 0
CSN1S1 CSN1S1 P47710 Alpha-S1-casein chr4 GO:0009719 Not Cancer Driver No 31 0.168 109 16 0.147 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0009719 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSTF2_ENST00000372972 CSTF2 P33240 Cleavage stimulation factor subunit 2 chrX GO:0009719 Not Cancer Driver No 85 0.147 484 72 0.149 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0009719 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0009719 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTSB CTSB P07858 Cathepsin B chr8 GO:0009719 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0009719 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0009719 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSS CTSS P25774 Cathepsin S chr1 GO:0009719 Not Cancer Driver No 54 0.163 0 0 0.0 0
CXCL8 CXCL8 P10145 Interleukin-8 chr4 GO:0009719 Not Cancer Driver No 17 0.172 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009719 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYBB CYBB P04839 Cytochrome b-245 heavy chain chrX GO:0009719 Not Cancer Driver No 109 0.191 11 3 0.273 65
CYC1 CYC1 P08574 Cytochrome c1, heme protein, mitochondrial chr8 GO:0009719 Not Cancer Driver No 65 0.2 35 8 0.229 2
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0009719 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0009719 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYSLTR2_ENST00000614739 CYSLTR2 Q9NS75 Cysteinyl leukotriene receptor 2 chr13 GO:0009719 Census, Compendium Yes 64 0.185 0 0 0.0 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0009719 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0009719 Not Cancer Driver No 131 0.11 681 68 0.1 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0009719 Not Cancer Driver No 98 0.204 5 0 0.0 9
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0009719 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0009719 Not Cancer Driver No 154 0.159 280 55 0.196 1
DEFB124 DEFB124 Q8NES8 Beta-defensin 124 chr20 GO:0009719 Not Cancer Driver No 9 0.127 3 0 0.0 0
DHH DHH O43323 Desert hedgehog protein chr12 GO:0009719 Not Cancer Driver No 36 0.091 57 7 0.123 1
DIAPH1 DIAPH1 O60610 Protein diaphanous homolog 1 chr5 GO:0009719 Not Cancer Driver No 118 0.093 692 57 0.082 1
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0009719 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0009719 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0009719 Census Yes 138 0.159 270 43 0.159 22
DNMT1_ENST00000340748 DNMT1 P26358 DNA (cytosine-5)-methyltransferase 1 chr19 GO:0009719 Not Cancer Driver No 203 0.126 702 78 0.111 4
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0009719 Census, Compendium Yes 194 0.213 371 59 0.159 16
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0009719 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0009719 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSG1 DSG1 Q02413 Desmoglein-1 chr18 GO:0009719 Not Cancer Driver No 250 0.238 496 130 0.262 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0009719 Not Cancer Driver No 112 0.121 112 4 0.036 2
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0009719 Not Cancer Driver No 84 0.457 0 0 0.0 0
DUSP3 DUSP3 P51452 Dual specificity protein phosphatase 3 chr17 GO:0009719 Not Cancer Driver No 21 0.114 4 1 0.25 0
DYNC1LI2 DYNC1LI2 O43237 Cytoplasmic dynein 1 light intermediate chain 2 chr16 GO:0009719 Not Cancer Driver No 43 0.087 211 14 0.066 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0009719 Not Cancer Driver No 49 0.112 272 23 0.085 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0009719 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0009719 Not Cancer Driver No 62 0.145 21 6 0.286 2
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0009719 Not Cancer Driver No 112 0.253 56 19 0.339 6
EEF1A1 EEF1A1 P68104 Elongation factor 1-alpha 1 chr6 GO:0009719 Not Cancer Driver No 109 0.236 100 14 0.14 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0009719 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0009719 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0009719 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0009719 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR3 EGR3 Q06889 Early growth response protein 3 chr8 GO:0009719 Not Cancer Driver No 60 0.155 252 46 0.183 0
EHD1_ENST00000359393 EHD1 Q9H4M9 EH domain-containing protein 1 chr11 GO:0009719 Not Cancer Driver No 72 0.135 90 12 0.133 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0009719 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0009719 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0009719 Not Cancer Driver No 26 0.12 54 6 0.111 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0009719 Not Cancer Driver No 118 0.306 117 34 0.291 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0009719 Not Cancer Driver No 51 0.119 327 34 0.104 0
EME1_ENST00000338165 EME1 Q96AY2 Crossover junction endonuclease EME1 chr17 GO:0009719 Not Cancer Driver No 56 0.098 296 30 0.101 0
ENG ENG P17813 Endoglin chr9 GO:0009719 Not Cancer Driver No 60 0.091 114 15 0.132 32
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009719 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0009719 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA8 EPHA8 P29322 Ephrin type-A receptor 8 chr1 GO:0009719 Not Cancer Driver No 197 0.196 121 17 0.14 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0009719 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPO EPO P01588 Erythropoietin chr7 GO:0009719 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0009719 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0009719 Census, Compendium Yes 428 0.327 323 116 0.359 2
ERRFI1 ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 chr1 GO:0009719 Not Cancer Driver No 55 0.119 297 37 0.125 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0009719 Census, Compendium Yes 121 0.203 195 27 0.138 2
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0009719 Census, Compendium Yes 93 0.13 12 1 0.083 9
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0009719 Census, Compendium Yes 120 0.161 284 44 0.155 11
EZR EZR P15311 Ezrin chr6 GO:0009719 Census Yes 66 0.113 295 35 0.119 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0009719 Not Cancer Driver No 74 0.159 50 7 0.14 108
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0009719 Not Cancer Driver No 25 0.174 141 24 0.17 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0009719 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBN1 FBN1 P35555 Fibrillin-1 chr15 GO:0009719 Not Cancer Driver No 466 0.162 110 16 0.145 360
FBXO32 FBXO32 Q969P5 F-box only protein 32 chr8 GO:0009719 Not Cancer Driver No 54 0.152 0 0 0.0 0
FCER1G FCER1G P30273 High affinity immunoglobulin epsilon receptor subunit gamma chr1 GO:0009719 Not Cancer Driver No 10 0.116 13 2 0.154 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0009719 Census Yes 51 0.165 99 30 0.303 0
FDX1 FDX1 P10109 Adrenodoxin, mitochondrial chr11 GO:0009719 Not Cancer Driver No 12 0.065 61 2 0.033 0
FER FER P16591 Tyrosine-protein kinase Fer chr5 GO:0009719 Not Cancer Driver No 114 0.139 145 21 0.145 0
FGB FGB P02675 Fibrinogen beta chain chr4 GO:0009719 Not Cancer Driver No 89 0.181 143 29 0.203 7
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0009719 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0009719 Not Cancer Driver No 84 0.335 97 51 0.526 7
FIBIN FIBIN Q8TAL6 Fin bud initiation factor homolog chr11 GO:0009719 Not Cancer Driver No 42 0.199 51 12 0.235 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0009719 Census, Compendium Yes 200 0.201 64 27 0.422 0
FOLR1_ENST00000393681 FOLR1 P15328 Folate receptor alpha chr11 GO:0009719 Not Cancer Driver No 41 0.16 13 3 0.231 0
FOLR2 FOLR2 P14207 Folate receptor beta chr11 GO:0009719 Not Cancer Driver No 32 0.125 6 0 0.0 0
FOS FOS P01100 Protein c-Fos chr14 GO:0009719 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSB FOSB P53539 Protein FosB chr19 GO:0009719 Not Cancer Driver No 50 0.148 313 44 0.141 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0009719 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0009719 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0009719 Census, Compendium Yes 70 0.104 595 68 0.114 0
FPR2 FPR2 P25090 N-formyl peptide receptor 2 chr19 GO:0009719 Not Cancer Driver No 96 0.274 26 5 0.192 0
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0009719 Not Cancer Driver No 226 0.325 28 11 0.393 16
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0009719 Not Cancer Driver No 92 0.171 70 13 0.186 0
GABPA_ENST00000400075 GABPA Q06546 GA-binding protein alpha chain chr21 GO:0009719 Not Cancer Driver No 58 0.128 103 8 0.078 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0009719 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0009719 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0009719 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0009719 Not Cancer Driver No 188 0.403 19 13 0.684 11
GAL GAL P22466 Galanin peptides chr11 GO:0009719 Not Cancer Driver No 17 0.138 36 2 0.056 1
GAREM1 GAREM1 Q9H706 GRB2-associated and regulator of MAPK protein 1 chr18 GO:0009719 Not Cancer Driver No 128 0.146 408 50 0.123 0
GAS2L1_ENST00000621062 GAS2L1 Q99501 GAS2-like protein 1 chr22 GO:0009719 Not Cancer Driver No 76 0.112 474 50 0.105 0
GATA1 GATA1 P15976 Erythroid transcription factor chrX GO:0009719 Census, Compendium Yes 68 0.165 242 41 0.169 5
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009719 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0009719 Not Cancer Driver No 57 0.096 476 51 0.107 10
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0009719 Not Cancer Driver No 74 0.138 38 5 0.132 171
GCGR GCGR P47871 Glucagon receptor chr17 GO:0009719 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0009719 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0009719 Not Cancer Driver No 73 0.115 167 18 0.108 3
GCLM GCLM P48507 Glutamate--cysteine ligase regulatory subunit chr1 GO:0009719 Not Cancer Driver No 32 0.117 31 3 0.097 0
GFER GFER P55789 FAD-linked sulfhydryl oxidase ALR chr16 GO:0009719 Not Cancer Driver No 10 0.049 97 4 0.041 1
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0009719 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0009719 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0009719 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0009719 Not Cancer Driver No 85 0.232 4 0 0.0 2
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0009719 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0009719 Not Cancer Driver No 34 0.15 0 0 0.0 46
GLB1 GLB1 P16278 Beta-galactosidase chr3 GO:0009719 Not Cancer Driver No 72 0.106 54 6 0.111 99
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0009719 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0009719 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLP2R GLP2R O95838 Glucagon-like peptide 2 receptor chr17 GO:0009719 Not Cancer Driver No 124 0.224 63 14 0.222 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0009719 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0009719 Not Cancer Driver No 106 0.235 58 14 0.241 0
GNB1_ENST00000378609 GNB1 P62873 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 chr1 GO:0009719 Not Cancer Driver No 45 0.132 24 2 0.083 16
GNG2_ENST00000615906 GNG2 P59768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 chr14 GO:0009719 Not Cancer Driver No 17 0.239 12 3 0.25 0
GNRHR GNRHR P30968 Gonadotropin-releasing hormone receptor chr4 GO:0009719 Not Cancer Driver No 40 0.122 15 1 0.067 14
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0009719 Not Cancer Driver No 41 0.138 72 1 0.014 0
GOT1 GOT1 P17174 Aspartate aminotransferase, cytoplasmic chr10 GO:0009719 Not Cancer Driver No 56 0.136 35 5 0.143 0
GPD1 GPD1 P21695 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic chr12 GO:0009719 Not Cancer Driver No 59 0.169 2 0 0.0 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0009719 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0009719 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPR173 GPR173 Q9NS66 Probable G-protein coupled receptor 173 chrX GO:0009719 Not Cancer Driver No 57 0.153 12 0 0.0 0
GPR83 GPR83 Q9NYM4 G-protein coupled receptor 83 chr11 GO:0009719 Not Cancer Driver No 93 0.22 32 10 0.312 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0009719 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0009719 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0009719 Not Cancer Driver No 312 0.257 323 51 0.158 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0009719 Not Cancer Driver No 56 0.133 146 13 0.089 0
GSTM2 GSTM2 P28161 Glutathione S-transferase Mu 2 chr1 GO:0009719 Not Cancer Driver No 26 0.119 5 0 0.0 0
GSTM3_ENST00000361066 GSTM3 P21266 Glutathione S-transferase Mu 3 chr1 GO:0009719 Not Cancer Driver No 32 0.142 0 0 0.0 0
HAPLN3_ENST00000359595 HAPLN3 Q96S86 Hyaluronan and proteoglycan link protein 3 chr15 GO:0009719 Not Cancer Driver No 61 0.169 31 5 0.161 0
HAS1 HAS1 Q92839 Hyaluronan synthase 1 chr19 GO:0009719 Not Cancer Driver No 115 0.199 9 0 0.0 0
HAS2 HAS2 Q92819 Hyaluronan synthase 2 chr8 GO:0009719 Not Cancer Driver No 100 0.181 17 7 0.412 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0009719 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0009719 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0009719 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0009719 Not Cancer Driver No 187 0.155 631 58 0.092 3
HDAC1 HDAC1 Q13547 Histone deacetylase 1 chr1 GO:0009719 Not Cancer Driver No 47 0.098 135 10 0.074 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0009719 Not Cancer Driver No 46 0.094 145 14 0.097 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0009719 Not Cancer Driver No 37 0.132 226 32 0.142 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0009719 Not Cancer Driver No 92 0.181 29 4 0.138 19
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0009719 Not Cancer Driver No 46 0.16 81 13 0.16 0
HNRNPAB HNRNPAB Q99729 Heterogeneous nuclear ribonucleoprotein A/B chr5 GO:0009719 Not Cancer Driver No 31 0.093 202 11 0.054 0
HNRNPD HNRNPD Q14103 Heterogeneous nuclear ribonucleoprotein D0 chr4 GO:0009719 Not Cancer Driver No 39 0.11 206 19 0.092 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0009719 Not Cancer Driver No 77 0.093 504 45 0.089 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0009719 Not Cancer Driver No 35 0.085 339 25 0.074 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0009719 Census, Compendium Yes 37 0.118 205 26 0.127 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0009719 Not Cancer Driver No 60 0.144 12 0 0.0 0
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0009719 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSD11B2 HSD11B2 P80365 11-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0009719 Not Cancer Driver No 27 0.067 30 0 0.0 14
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 GO:0009719 Not Cancer Driver No 69 0.185 25 3 0.12 0
HSD3B2_ENST00000369416 HSD3B2 P26439 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 GO:0009719 Not Cancer Driver No 83 0.223 24 9 0.375 28
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009719 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSP90B1 HSP90B1 P14625 Endoplasmin chr12 GO:0009719 Not Cancer Driver No 94 0.117 268 35 0.131 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0009719 Not Cancer Driver No 73 0.112 282 35 0.124 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0009719 Not Cancer Driver No 91 0.233 33 15 0.455 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0009719 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0009719 Not Cancer Driver No 52 0.11 8 1 0.125 0
ICAM1 ICAM1 P05362 Intercellular adhesion molecule 1 chr19 GO:0009719 Not Cancer Driver No 61 0.115 251 28 0.112 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0009719 Not Cancer Driver No 20 0.129 17 6 0.353 0
IER2_ENST00000587885 IER2 Q9BTL4 Immediate early response gene 2 protein chr19 GO:0009719 Not Cancer Driver No 16 0.072 178 13 0.073 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0009719 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0009719 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGFBP2 IGFBP2 P18065 Insulin-like growth factor-binding protein 2 chr2 GO:0009719 Not Cancer Driver No 32 0.098 171 24 0.14 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0009719 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGFBP7 IGFBP7 Q16270 Insulin-like growth factor-binding protein 7 chr4 GO:0009719 Not Cancer Driver No 22 0.078 100 12 0.12 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0009719 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0009719 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL22_ENST00000328087 IL22 Q9GZX6 Interleukin-22 chr12 GO:0009719 Not Cancer Driver No 32 0.179 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0009719 Not Cancer Driver No 133 0.161 420 64 0.152 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0009719 Not Cancer Driver No 35 0.165 58 7 0.121 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0009719 Not Cancer Driver No 49 0.153 84 12 0.143 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0009719 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0009719 Not Cancer Driver No 61 0.15 98 5 0.051 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0009719 Not Cancer Driver No 42 0.094 34 2 0.059 7
IPO5_ENST00000490680 IPO5 O00410 Importin-5 chr13 GO:0009719 Not Cancer Driver No 128 0.117 52 3 0.058 0
IQGAP1 IQGAP1 P46940 Ras GTPase-activating-like protein IQGAP1 chr15 GO:0009719 Not Cancer Driver No 183 0.11 351 35 0.1 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0009719 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGA2 ITGA2 P17301 Integrin alpha-2 chr5 GO:0009719 Not Cancer Driver No 166 0.141 26 0 0.0 0
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0009719 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0009719 Not Cancer Driver No 254 0.246 97 27 0.278 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0009719 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0009719 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0009719 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0009719 Not Cancer Driver No 359 0.133 394 57 0.145 1
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0009719 Census, Compendium Yes 136 0.12 59 5 0.085 5
JUN JUN P05412 Transcription factor Jun chr1 GO:0009719 Census Yes 35 0.106 281 25 0.089 0
JUP JUP P14923 Junction plakoglobin chr17 GO:0009719 Not Cancer Driver No 112 0.15 241 37 0.154 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0009719 Not Cancer Driver No 88 0.105 251 17 0.068 0
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0009719 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0009719 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0009719 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0009719 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0009719 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0009719 Not Cancer Driver No 219 0.142 388 58 0.149 0
KIDINS220 KIDINS220 Q9ULH0 Kinase D-interacting substrate of 220 kDa chr2 GO:0009719 Not Cancer Driver No 245 0.138 683 113 0.165 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0009719 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:0009719 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0009719 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLF9 KLF9 Q13886 Krueppel-like factor 9 chr9 GO:0009719 Not Cancer Driver No 34 0.139 154 24 0.156 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0009719 Not Cancer Driver No 90 0.142 50 8 0.16 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0009719 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KNSTRN KNSTRN Q9Y448 Small kinetochore-associated protein chr15 GO:0009719 Census Yes 75 0.237 246 67 0.272 0
KRT19 KRT19 P08727 Keratin, type I cytoskeletal 19 chr17 GO:0009719 Not Cancer Driver No 57 0.142 165 19 0.115 0
LAMTOR1 LAMTOR1 Q6IAA8 Ragulator complex protein LAMTOR1 chr11 GO:0009719 Not Cancer Driver No 13 0.081 96 7 0.073 0
LAMTOR2 LAMTOR2 Q9Y2Q5 Ragulator complex protein LAMTOR2 chr1 GO:0009719 Not Cancer Driver No 12 0.096 0 0 0.0 0
LAMTOR3 LAMTOR3 Q9UHA4 Ragulator complex protein LAMTOR3 chr4 GO:0009719 Not Cancer Driver No 12 0.097 0 0 0.0 0
LAMTOR4 LAMTOR4 Q0VGL1 Ragulator complex protein LAMTOR4 chr7 GO:0009719 Not Cancer Driver No 8 0.081 4 0 0.0 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0009719 Not Cancer Driver No 10 0.11 17 0 0.0 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0009719 Not Cancer Driver No 133 0.113 97 10 0.103 1
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0009719 Not Cancer Driver No 43 0.098 28 2 0.071 34
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0009719 Not Cancer Driver No 119 0.138 63 3 0.048 104
LDOC1 LDOC1 O95751 Protein LDOC1 chrX GO:0009719 Not Cancer Driver No 48 0.329 23 10 0.435 0
LEP LEP P41159 Leptin chr7 GO:0009719 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0009719 Not Cancer Driver No 243 0.209 57 11 0.193 0
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0009719 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHCGR LHCGR P22888 Lutropin-choriogonadotropic hormone receptor chr2 GO:0009719 Not Cancer Driver No 181 0.259 12 8 0.667 25
LMO2_ENST00000395833 LMO2 P25791 Rhombotin-2 chr11 GO:0009719 Census Yes 35 0.222 14 1 0.071 0
LRP1 LRP1 Q07954 Prolow-density lipoprotein receptor-related protein 1 chr12 GO:0009719 Not Cancer Driver No 664 0.146 317 52 0.164 1
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0009719 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0009719 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAGI2 MAGI2 Q86UL8 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 chr7 GO:0009719 Not Cancer Driver No 305 0.21 1086 201 0.185 0
MAOB MAOB P27338 Amine oxidase [flavin-containing] B chrX GO:0009719 Not Cancer Driver No 75 0.144 44 6 0.136 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0009719 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0009719 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0009719 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0009719 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARS MARS1 P56192 Methionine--tRNA ligase, cytoplasmic chr12 GO:0009719 Not Cancer Driver No 91 0.101 151 16 0.106 8
MAS1 MAS1 P04201 Proto-oncogene Mas chr6 GO:0009719 Not Cancer Driver No 47 0.145 5 2 0.4 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0009719 Not Cancer Driver No 52 0.171 304 52 0.171 0
MC4R MC4R P32245 Melanocortin receptor 4 chr18 GO:0009719 Not Cancer Driver No 57 0.172 2 0 0.0 29
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0009719 Not Cancer Driver No 101 0.14 128 22 0.172 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0009719 Not Cancer Driver No 15 0.105 20 2 0.1 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0009719 Census, Compendium Yes 56 0.114 297 37 0.125 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0009719 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0009719 Not Cancer Driver No 92 0.195 408 81 0.199 0
METTL21C METTL21C Q5VZV1 Protein-lysine methyltransferase METTL21C chr13 GO:0009719 Not Cancer Driver No 54 0.205 47 13 0.277 0
MGARP MGARP Q8TDB4 Protein MGARP chr4 GO:0009719 Not Cancer Driver No 25 0.104 207 22 0.106 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:0009719 Not Cancer Driver No 222 0.116 1490 178 0.119 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0009719 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0009719 Not Cancer Driver No 123 0.186 29 6 0.207 2
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0009719 Not Cancer Driver No 68 0.181 64 11 0.172 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0009719 Census, Compendium Yes 379 0.149 296 37 0.125 18
MTRNR2L5 MTRNR2L5 P0CJ72 Humanin-like 5 chr10 GO:0009719 Not Cancer Driver No 1 0.042 0 0 0.0 0
MTSS1L MTSS2 Q765P7 Protein MTSS 2 chr16 GO:0009719 Not Cancer Driver No 62 0.083 582 49 0.084 0
MUS81 MUS81 Q96NY9 Crossover junction endonuclease MUS81 chr11 GO:0009719 Not Cancer Driver No 67 0.122 232 38 0.164 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009719 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0009719 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYOD1 MYOD1 P15172 Myoblast determination protein 1 chr11 GO:0009719 Census Yes 45 0.141 246 33 0.134 0
NCL NCL P19338 Nucleolin chr2 GO:0009719 Not Cancer Driver No 85 0.12 569 68 0.12 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0009719 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NDNF NDNF Q8TB73 Protein NDNF chr4 GO:0009719 Not Cancer Driver No 125 0.22 129 29 0.225 1
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0009719 Not Cancer Driver No 92 0.169 285 39 0.137 12
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0009719 Not Cancer Driver No 62 0.108 153 11 0.072 0
NFE2L2 NFE2L2 Q16236 Nuclear factor erythroid 2-related factor 2 chr2 GO:0009719 Census, Compendium Yes 228 0.377 402 62 0.154 4
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0009719 Not Cancer Driver No 104 0.107 344 38 0.11 0
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0009719 Not Cancer Driver No 57 0.133 172 25 0.145 0
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0009719 Not Cancer Driver No 84 0.308 206 65 0.316 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0009719 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0009719 Not Cancer Driver No 169 0.163 40 4 0.1 15
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0009719 Census, Compendium Yes 363 0.142 686 87 0.127 3
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0009719 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 GO:0009719 Not Cancer Driver No 155 0.121 24 0 0.0 150
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0009719 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0009719 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0009719 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0009719 Not Cancer Driver No 62 0.104 252 24 0.095 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0009719 Not Cancer Driver No 110 0.184 261 38 0.146 0
NR4A3_ENST00000395097 NR4A3 Q92570 Nuclear receptor subfamily 4 group A member 3 chr9 GO:0009719 Census Yes 83 0.133 298 37 0.124 0
NSMF NSMF Q6X4W1 NMDA receptor synaptonuclear signaling and neuronal migration factor chr9 GO:0009719 Not Cancer Driver No 46 0.087 287 19 0.066 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0009719 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0009719 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0009719 Census, Compendium Yes 249 0.297 57 21 0.368 0
OCSTAMP OCSTAMP Q9BR26 Osteoclast stimulatory transmembrane protein chr20 GO:0009719 Not Cancer Driver No 22 0.039 52 6 0.115 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0009719 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0009719 Not Cancer Driver No 107 0.268 58 27 0.466 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0009719 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0009719 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0009719 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0009719 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0009719 Not Cancer Driver No 51 0.086 14 2 0.143 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0009719 Not Cancer Driver No 60 0.161 16 1 0.062 0
P2RY11 P2RY11 Q96G91 P2Y purinoceptor 11 chr19 GO:0009719 Not Cancer Driver No 47 0.126 31 1 0.032 0
P2RY12 P2RY12 Q9H244 P2Y purinoceptor 12 chr3 GO:0009719 Not Cancer Driver No 57 0.167 21 2 0.095 3
P2RY2_ENST00000393596 P2RY2 P41231 P2Y purinoceptor 2 chr11 GO:0009719 Not Cancer Driver No 67 0.178 60 13 0.217 0
P2RY4 P2RY4 P51582 P2Y purinoceptor 4 chrX GO:0009719 Not Cancer Driver No 66 0.181 10 2 0.2 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0009719 Not Cancer Driver No 50 0.152 10 5 0.5 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0009719 Not Cancer Driver No 129 0.133 254 37 0.146 0
PAPPA PAPPA Q13219 Pappalysin-1 chr9 GO:0009719 Not Cancer Driver No 370 0.227 239 37 0.155 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0009719 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0009719 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0009719 Census Yes 84 0.187 291 55 0.189 4
PCK1 PCK1 P35558 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] chr20 GO:0009719 Not Cancer Driver No 142 0.228 110 28 0.255 1
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0009719 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0009719 Not Cancer Driver No 30 0.115 22 3 0.136 1
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0009719 Not Cancer Driver No 139 0.185 336 61 0.182 2
PDCD7 PDCD7 Q8N8D1 Programmed cell death protein 7 chr15 GO:0009719 Not Cancer Driver No 47 0.097 275 15 0.055 0
PDE2A PDE2A O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase chr11 GO:0009719 Not Cancer Driver No 137 0.146 99 7 0.071 0
PDE3A PDE3A Q14432 cGMP-inhibited 3',5'-cyclic phosphodiesterase A chr12 GO:0009719 Not Cancer Driver No 274 0.24 527 114 0.216 6
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0009719 Not Cancer Driver No 119 0.162 363 42 0.116 0
PDE8A_ENST00000394553 PDE8A O60658 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A chr15 GO:0009719 Not Cancer Driver No 78 0.094 187 17 0.091 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0009719 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0009719 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0009719 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0009719 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0009719 Census, Compendium Yes 164 0.148 231 44 0.19 7
PDPK1 PDPK1 O15530 3-phosphoinositide-dependent protein kinase 1 chr16 GO:0009719 Not Cancer Driver No 33 0.059 121 12 0.099 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0009719 Not Cancer Driver No 32 0.113 238 23 0.097 0
PDXP PDXP Q96GD0 Chronophin chr22 GO:0009719 Not Cancer Driver No 14 0.047 38 4 0.105 0
PELP1_ENST00000574876 PELP1 Q8IZL8 Proline-, glutamic acid- and leucine-rich protein 1 chr17 GO:0009719 Not Cancer Driver No 134 0.119 610 82 0.134 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0009719 Not Cancer Driver No 109 0.408 142 62 0.437 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0009719 Not Cancer Driver No 81 0.172 48 11 0.229 0
PHEX PHEX P78562 Phosphate-regulating neutral endopeptidase PHEX chrX GO:0009719 Not Cancer Driver No 144 0.192 56 7 0.125 30
PID1 PID1 Q7Z2X4 PTB-containing, cubilin and LRP1-interacting protein chr2 GO:0009719 Not Cancer Driver No 70 0.28 24 10 0.417 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0009719 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0009719 Not Cancer Driver No 318 0.289 121 39 0.322 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0009719 Not Cancer Driver No 24 0.079 155 12 0.077 1
PKD1L1 PKD1L1 Q8TDX9 Polycystic kidney disease protein 1-like 1 chr7 GO:0009719 Not Cancer Driver No 492 0.173 518 97 0.187 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0009719 Not Cancer Driver No 113 0.117 375 35 0.093 10
PKLR PKLR P30613 Pyruvate kinase PKLR chr1 GO:0009719 Not Cancer Driver No 112 0.195 26 5 0.192 101
PLAT PLAT P00750 Tissue-type plasminogen activator chr8 GO:0009719 Not Cancer Driver No 89 0.158 15 2 0.133 0
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0009719 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLCG1_ENST00000373271 PLCG1 P19174 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 chr20 GO:0009719 Census, Compendium Yes 158 0.122 186 21 0.113 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0009719 Not Cancer Driver No 54 0.112 33 7 0.212 0
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0009719 Not Cancer Driver No 86 0.11 115 10 0.087 2
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0009719 Not Cancer Driver No 50 0.187 198 38 0.192 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0009719 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0009719 Census Yes 72 0.143 44 4 0.091 3
PPARGC1B PPARGC1B Q86YN6 Peroxisome proliferator-activated receptor gamma coactivator 1-beta chr5 GO:0009719 Not Cancer Driver No 125 0.122 845 99 0.117 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0009719 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0009719 Not Cancer Driver No 47 0.058 695 35 0.05 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009719 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAA2 PRKAA2 P54646 5'-AMP-activated protein kinase catalytic subunit alpha-2 chr1 GO:0009719 Not Cancer Driver No 128 0.232 98 26 0.265 0
PRKACA PRKACA P17612 cAMP-dependent protein kinase catalytic subunit alpha chr19 GO:0009719 Census Yes 53 0.151 24 0 0.0 2
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009719 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0009719 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0009719 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRNP PRNP P04156 Major prion protein chr20 GO:0009719 Not Cancer Driver No 36 0.142 115 7 0.061 18
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0009719 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTAFR_ENST00000305392 PTAFR P25105 Platelet-activating factor receptor chr1 GO:0009719 Not Cancer Driver No 42 0.123 0 0 0.0 0
PTGDR PTGDR Q13258 Prostaglandin D2 receptor chr14 GO:0009719 Not Cancer Driver No 74 0.206 14 9 0.643 0
PTGER2 PTGER2 P43116 Prostaglandin E2 receptor EP2 subtype chr14 GO:0009719 Not Cancer Driver No 64 0.179 52 5 0.096 0
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0009719 Not Cancer Driver No 81 0.166 118 17 0.144 0
PTGFR PTGFR P43088 Prostaglandin F2-alpha receptor chr1 GO:0009719 Not Cancer Driver No 105 0.292 2 0 0.0 0
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0009719 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0009719 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0009719 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN12 PTPN12 Q05209 Tyrosine-protein phosphatase non-receptor type 12 chr7 GO:0009719 Not Cancer Driver No 102 0.131 516 60 0.116 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0009719 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPRU PTPRU Q92729 Receptor-type tyrosine-protein phosphatase U chr1 GO:0009719 Not Cancer Driver No 248 0.172 325 64 0.197 0
RAB35 RAB35 Q15286 Ras-related protein Rab-35 chr12 GO:0009719 Not Cancer Driver No 25 0.124 25 2 0.08 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0009719 Not Cancer Driver No 42 0.124 47 5 0.106 3
RANGAP1_ENST00000356244 RANGAP1 P46060 Ran GTPase-activating protein 1 chr22 GO:0009719 Not Cancer Driver No 65 0.111 159 17 0.107 0
RAN_ENST00000392369 RAN P62826 GTP-binding nuclear protein Ran chr12 GO:0009719 Not Cancer Driver No 20 0.093 14 1 0.071 0
RAP1A_ENST00000356415 RAP1A P62834 Ras-related protein Rap-1A chr1 GO:0009719 Not Cancer Driver No 27 0.147 5 0 0.0 0
RAP1B_ENST00000393436 RAP1B P61224 Ras-related protein Rap-1b chr12 GO:0009719 Not Cancer Driver No 26 0.141 14 3 0.214 0
RAP1GAP_ENST00000374765 RAP1GAP P47736 Rap1 GTPase-activating protein 1 chr1 GO:0009719 Not Cancer Driver No 81 0.122 313 39 0.125 0
RAPGEF1_ENST00000372189 RAPGEF1 Q13905 Rap guanine nucleotide exchange factor 1 chr9 GO:0009719 Not Cancer Driver No 158 0.147 589 87 0.148 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0009719 Not Cancer Driver No 216 0.144 803 116 0.144 0
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0009719 Not Cancer Driver No 97 0.105 197 19 0.096 0
RARA RARA P10276 Retinoic acid receptor alpha chr17 GO:0009719 Census, Compendium Yes 70 0.152 167 14 0.084 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 GO:0009719 Not Cancer Driver No 57 0.106 218 19 0.087 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0009719 Not Cancer Driver No 71 0.122 297 37 0.125 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0009719 Not Cancer Driver No 132 0.133 495 71 0.143 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009719 Compendium Yes 75 0.136 400 48 0.12 0
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0009719 Not Cancer Driver No 142 0.129 868 113 0.13 4
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0009719 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0009719 Not Cancer Driver No 63 0.117 143 20 0.14 0
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0009719 Not Cancer Driver No 184 0.136 780 103 0.132 0
ROCK2 ROCK2 O75116 Rho-associated protein kinase 2 chr2 GO:0009719 Not Cancer Driver No 145 0.104 732 81 0.111 0
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0009719 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL27_ENST00000253788 RPL27 P61353 60S ribosomal protein L27 chr17 GO:0009719 Not Cancer Driver No 21 0.154 13 3 0.231 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0009719 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0009719 Not Cancer Driver No 176 0.132 241 21 0.087 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0009719 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0009719 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:0009719 Compendium Yes 29 0.073 61 1 0.016 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0009719 Not Cancer Driver No 42 0.105 83 5 0.06 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0009719 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0009719 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0009719 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SCGB1A1 SCGB1A1 P11684 Uteroglobin chr11 GO:0009719 Not Cancer Driver No 12 0.132 14 2 0.143 0
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0009719 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0009719 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0009719 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0009719 Not Cancer Driver No 129 0.199 57 11 0.193 0
SDC1_ENST00000254351 SDC1 P18827 Syndecan-1 chr2 GO:0009719 Not Cancer Driver No 31 0.1 259 30 0.116 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0009719 Not Cancer Driver No 64 0.17 22 2 0.091 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0009719 Not Cancer Driver No 51 0.122 57 5 0.088 0
SESN1_ENST00000356644 SESN1 Q9Y6P5 Sestrin-1 chr6 GO:0009719 Not Cancer Driver No 45 0.091 48 4 0.083 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0009719 Not Cancer Driver No 74 0.154 147 26 0.177 0
SESN3 SESN3 P58005 Sestrin-3 chr11 GO:0009719 Not Cancer Driver No 84 0.171 44 4 0.091 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0009719 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SFR1 SFR1 Q86XK3 Swi5-dependent recombination DNA repair protein 1 homolog chr10 GO:0009719 Not Cancer Driver No 21 0.086 109 12 0.11 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0009719 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0009719 Census, Compendium Yes 58 0.135 86 16 0.186 0
SH3BP4_ENST00000392011 SH3BP4 Q9P0V3 SH3 domain-binding protein 4 chr2 GO:0009719 Not Cancer Driver No 143 0.148 241 43 0.178 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0009719 Not Cancer Driver No 76 0.216 214 50 0.234 0
SHMT1 SHMT1 P34896 Serine hydroxymethyltransferase, cytosolic chr17 GO:0009719 Not Cancer Driver No 51 0.106 32 7 0.219 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0009719 Compendium Yes 172 0.135 617 73 0.118 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009719 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0009719 Not Cancer Driver No 56 0.144 85 17 0.2 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0009719 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0009719 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0009719 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0009719 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0009719 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC25A33 SLC25A33 Q9BSK2 Solute carrier family 25 member 33 chr1 GO:0009719 Not Cancer Driver No 23 0.072 4 0 0.0 0
SLC26A3 SLC26A3 P40879 Chloride anion exchanger chr7 GO:0009719 Not Cancer Driver No 159 0.208 3 1 0.333 26
SLC26A5 SLC26A5 P58743 Prestin chr7 GO:0009719 Not Cancer Driver No 135 0.181 59 11 0.186 0
SLC26A6 SLC26A6 Q9BXS9 Solute carrier family 26 member 6 chr3 GO:0009719 Not Cancer Driver No 68 0.09 87 13 0.149 0
SLC30A10 SLC30A10 Q6XR72 Zinc transporter 10 chr1 GO:0009719 Not Cancer Driver No 68 0.14 61 10 0.164 2
SLC34A1 SLC34A1 Q06495 Sodium-dependent phosphate transport protein 2A chr5 GO:0009719 Not Cancer Driver No 92 0.144 46 8 0.174 9
SLC34A2 SLC34A2 O95436 Sodium-dependent phosphate transport protein 2B chr4 GO:0009719 Census Yes 132 0.191 65 15 0.231 1
SLC38A9 SLC38A9 Q8NBW4 Sodium-coupled neutral amino acid transporter 9 chr5 GO:0009719 Not Cancer Driver No 57 0.102 33 2 0.061 0
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0009719 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0009719 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC8A1_ENST00000332839 SLC8A1 P32418 Sodium/calcium exchanger 1 chr2 GO:0009719 Not Cancer Driver No 305 0.313 158 48 0.304 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0009719 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0009719 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0009719 Not Cancer Driver No 351 0.23 40 9 0.225 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0009719 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0009719 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0009719 Census, Compendium Yes 200 0.162 717 114 0.159 21
SMPD3 SMPD3 Q9NY59 Sphingomyelin phosphodiesterase 3 chr16 GO:0009719 Not Cancer Driver No 92 0.14 224 29 0.129 0
SMYD3 SMYD3 Q9H7B4 Histone-lysine N-methyltransferase SMYD3 chr1 GO:0009719 Not Cancer Driver No 59 0.138 2 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0009719 Not Cancer Driver No 52 0.194 52 9 0.173 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0009719 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0009719 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0009719 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0009719 Not Cancer Driver No 84 0.157 297 46 0.155 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0009719 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOST SOST Q9BQB4 Sclerostin chr17 GO:0009719 Not Cancer Driver No 30 0.141 90 12 0.133 3
SOX10_ENST00000360880 SOX10 P56693 Transcription factor SOX-10 chr22 GO:0009719 Not Cancer Driver No 66 0.142 421 62 0.147 14
SOX30 SOX30 O94993 Transcription factor SOX-30 chr5 GO:0009719 Not Cancer Driver No 103 0.137 659 89 0.135 0
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0009719 Compendium Yes 86 0.169 495 82 0.166 18
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0009719 Not Cancer Driver No 101 0.11 329 20 0.061 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0009719 Census Yes 53 0.099 130 11 0.085 1
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0009719 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0009719 Not Cancer Driver No 48 0.189 0 0 0.0 21
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0009719 Not Cancer Driver No 127 0.111 528 64 0.121 4
SREBF2 SREBF2 Q12772 Sterol regulatory element-binding protein 2 chr22 GO:0009719 Not Cancer Driver No 124 0.109 357 43 0.12 0
SSH1 SSH1 Q8WYL5 Protein phosphatase Slingshot homolog 1 chr12 GO:0009719 Not Cancer Driver No 129 0.123 658 85 0.129 0
SSTR2 SSTR2 P30874 Somatostatin receptor type 2 chr17 GO:0009719 Not Cancer Driver No 54 0.146 22 7 0.318 0
SSTR3 SSTR3 P32745 Somatostatin receptor type 3 chr22 GO:0009719 Not Cancer Driver No 94 0.225 110 26 0.236 0
SSTR4 SSTR4 P31391 Somatostatin receptor type 4 chr20 GO:0009719 Not Cancer Driver No 129 0.332 39 12 0.308 0
SSTR5 SSTR5 P35346 Somatostatin receptor type 5 chr16 GO:0009719 Not Cancer Driver No 60 0.165 45 12 0.267 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0009719 Census, Compendium Yes 110 0.143 152 15 0.099 19
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0009719 Census, Compendium Yes 93 0.118 144 19 0.132 5
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0009719 Not Cancer Driver No 59 0.239 58 12 0.207 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009719 Census, Compendium Yes 75 0.173 135 14 0.104 9
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0009719 Not Cancer Driver No 34 0.19 122 23 0.189 0
SYAP1 SYAP1 Q96A49 Synapse-associated protein 1 chrX GO:0009719 Not Cancer Driver No 31 0.088 221 22 0.1 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0009719 Census Yes 96 0.151 131 27 0.206 5
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0009719 Not Cancer Driver No 31 0.24 18 4 0.222 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0009719 Not Cancer Driver No 69 0.17 28 2 0.071 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0009719 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAT TAT P17735 Tyrosine aminotransferase chr16 GO:0009719 Not Cancer Driver No 102 0.225 75 21 0.28 1
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0009719 Not Cancer Driver No 35 0.088 197 12 0.061 4
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0009719 Not Cancer Driver No 39 0.207 25 2 0.08 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0009719 Compendium Yes 61 0.18 285 52 0.182 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009719 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0009719 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0009719 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0009719 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0009719 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0009719 Not Cancer Driver No 123 0.179 107 26 0.243 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0009719 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0009719 Not Cancer Driver No 188 0.161 320 58 0.181 0
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0009719 Not Cancer Driver No 87 0.189 113 28 0.248 33
TICAM1 TICAM1 Q8IUC6 TIR domain-containing adapter molecule 1 chr19 GO:0009719 Not Cancer Driver No 92 0.129 443 66 0.149 1
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0009719 Not Cancer Driver No 154 0.127 367 51 0.139 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0009719 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0009719 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0009719 Not Cancer Driver No 99 0.124 1 0 0.0 0
TMEM107_ENST00000437139 TMEM107 Q6UX40 Transmembrane protein 107 chr17 GO:0009719 Not Cancer Driver No 12 0.086 0 0 0.0 1
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0009719 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM38A TMEM38A Q9H6F2 Trimeric intracellular cation channel type A chr19 GO:0009719 Not Cancer Driver No 54 0.181 43 10 0.233 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0009719 Not Cancer Driver No 47 0.162 37 7 0.189 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009719 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11B TNFRSF11B O00300 Tumor necrosis factor receptor superfamily member 11B chr8 GO:0009719 Not Cancer Driver No 79 0.197 17 3 0.176 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0009719 Not Cancer Driver No 28 0.153 1 0 0.0 0
TOMM70 TOMM70 O94826 Mitochondrial import receptor subunit TOM70 chr3 GO:0009719 Not Cancer Driver No 59 0.097 140 8 0.057 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0009719 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPH2 TPH2 Q8IWU9 Tryptophan 5-hydroxylase 2 chr12 GO:0009719 Not Cancer Driver No 118 0.241 55 17 0.309 1
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0009719 Census Yes 311 0.132 1990 266 0.134 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0009719 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRERF1_ENST00000372922 TRERF1 Q96PN7 Transcriptional-regulating factor 1 chr6 GO:0009719 Not Cancer Driver No 226 0.188 957 167 0.175 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0009719 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM24 TRIM24 O15164 Transcription intermediary factor 1-alpha chr7 GO:0009719 Census, Compendium Yes 120 0.114 537 61 0.114 0
TRIM25 TRIM25 Q14258 E3 ubiquitin/ISG15 ligase TRIM25 chr17 GO:0009719 Not Cancer Driver No 59 0.094 225 20 0.089 0
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0009719 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM63 TRIM63 Q969Q1 E3 ubiquitin-protein ligase TRIM63 chr1 GO:0009719 Not Cancer Driver No 47 0.133 71 13 0.183 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0009719 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0009719 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0009719 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSHB_ENST00000369517 TSHB P01222 Thyrotropin subunit beta chr1 GO:0009719 Not Cancer Driver No 34 0.246 0 0 0.0 0
TSHR TSHR P16473 Thyrotropin receptor chr14 GO:0009719 Census Yes 128 0.168 38 9 0.237 39
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0009719 Not Cancer Driver No 5 0.03 1 0 0.0 0
TXNIP TXNIP Q9H3M7 Thioredoxin-interacting protein chr1 GO:0009719 Not Cancer Driver No 61 0.156 77 14 0.182 0
TYMS TYMS P04818 Thymidylate synthase chr18 GO:0009719 Not Cancer Driver No 22 0.07 41 0 0.0 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0009719 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0009719 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBR1 UBR1 Q8IWV7 E3 ubiquitin-protein ligase UBR1 chr15 GO:0009719 Not Cancer Driver No 170 0.097 165 15 0.091 18
UBR2 UBR2 Q8IWV8 E3 ubiquitin-protein ligase UBR2 chr6 GO:0009719 Not Cancer Driver No 172 0.098 228 30 0.132 0
UCN UCN P55089 Urocortin chr2 GO:0009719 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0009719 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP3 UCP3 P55916 Mitochondrial uncoupling protein 3 chr11 GO:0009719 Not Cancer Driver No 37 0.119 7 1 0.143 1
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0009719 Not Cancer Driver No 100 0.188 11 2 0.182 55
UMODL1_ENST00000408910 UMODL1 Q5DID0 Uromodulin-like 1 chr21 GO:0009719 Not Cancer Driver No 191 0.145 249 29 0.116 0
UROS_ENST00000368786 UROS P10746 Uroporphyrinogen-III synthase chr10 GO:0009719 Not Cancer Driver No 34 0.128 7 0 0.0 21
USP8 USP8 P40818 Ubiquitin carboxyl-terminal hydrolase 8 chr15 GO:0009719 Census, Compendium Yes 122 0.109 602 69 0.115 0
VCAM1 VCAM1 P19320 Vascular cell adhesion protein 1 chr1 GO:0009719 Not Cancer Driver No 188 0.254 110 28 0.255 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0009719 Not Cancer Driver No 124 0.15 222 38 0.171 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0009719 Not Cancer Driver No 84 0.18 316 57 0.18 1
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0009719 Not Cancer Driver No 63 0.113 445 49 0.11 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0009719 Not Cancer Driver No 26 0.1 102 6 0.059 1
WNT10B WNT10B O00744 Protein Wnt-10b chr12 GO:0009719 Not Cancer Driver No 56 0.144 84 16 0.19 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0009719 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0009719 Not Cancer Driver No 55 0.158 11 1 0.091 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0009719 Not Cancer Driver No 19 0.073 169 9 0.053 0
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0009719 Not Cancer Driver No 213 0.125 577 65 0.113 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0009719 Not Cancer Driver No 51 0.101 489 49 0.1 0
YES1_ENST00000314574 YES1 P07947 Tyrosine-protein kinase Yes chr18 GO:0009719 Not Cancer Driver No 65 0.12 62 10 0.161 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0009719 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0009719 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZFP36 ZFP36 P26651 mRNA decay activator protein ZFP36 chr19 GO:0009719 Not Cancer Driver No 43 0.132 262 34 0.13 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0009719 Compendium Yes 57 0.169 212 30 0.142 0
ZFP36L2 ZFP36L2 P47974 mRNA decay activator protein ZFP36L2 chr2 GO:0009719 Not Cancer Driver No 73 0.148 324 45 0.139 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0009719 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF366 ZNF366 Q8N895 Zinc finger protein 366 chr5 GO:0009719 Not Cancer Driver No 158 0.212 382 85 0.223 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0009719 Not Cancer Driver No 38 0.083 291 27 0.093 0